CN109952316A - 一种能够特异性地结合pd-1的抗体及其功能片段 - Google Patents
一种能够特异性地结合pd-1的抗体及其功能片段 Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
一种能够特异性地结合PD‑1的抗体及其功能片段,所述抗体或其功能片段包括PD‑1嵌合抗体及其功能片段及PD‑1人源化抗体及其功能片段。
Description
PCT国内申请,说明书已公开。
Claims (15)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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CN2016108270991 | 2016-09-14 | ||
CN201610827099 | 2016-09-14 | ||
PCT/CN2017/101082 WO2018050027A1 (zh) | 2016-09-14 | 2017-09-08 | 一种能够特异性地结合pd-1的抗体及其功能片段 |
Publications (1)
Publication Number | Publication Date |
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CN109952316A true CN109952316A (zh) | 2019-06-28 |
Family
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CN201780056736.2A Withdrawn CN109952316A (zh) | 2016-09-14 | 2017-09-08 | 一种能够特异性地结合pd-1的抗体及其功能片段 |
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EP (1) | EP3514177B1 (zh) |
JP (2) | JP7164528B2 (zh) |
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CN (1) | CN109952316A (zh) |
AU (1) | AU2017328309B2 (zh) |
BR (1) | BR112019004995A2 (zh) |
CA (1) | CA3036912C (zh) |
CL (1) | CL2019000658A1 (zh) |
CO (1) | CO2019002369A2 (zh) |
DO (1) | DOP2019000064A (zh) |
EA (1) | EA201990672A1 (zh) |
EC (1) | ECSP19018327A (zh) |
IL (1) | IL265333A (zh) |
MX (1) | MX2019002969A (zh) |
MY (1) | MY189618A (zh) |
PE (1) | PE20191076A1 (zh) |
PH (1) | PH12019500552A1 (zh) |
TN (1) | TN2019000081A1 (zh) |
WO (1) | WO2018050027A1 (zh) |
ZA (1) | ZA201902120B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022148414A1 (zh) * | 2021-01-08 | 2022-07-14 | 北京韩美药品有限公司 | 特异性结合pd-l1的抗体及其抗原结合片段 |
Families Citing this family (9)
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EP3370769A4 (en) | 2015-11-03 | 2019-05-22 | Janssen Biotech, Inc. | SPECIFIC TO TIM-3 BINDING ANTIBODIES AND THEIR USE |
MY189018A (en) | 2015-11-18 | 2022-01-19 | Merck Sharp & Dohme | Pd1 and/or lag3 binders |
EA201990672A1 (ru) * | 2016-09-14 | 2019-08-30 | Бэйцзин Ханми Фарм. Ко., Лтд. | Антитела, специфически связывающиеся с pd-1, и их функциональные фрагменты |
JP7079171B2 (ja) | 2017-08-03 | 2022-06-01 | アムジエン・インコーポレーテツド | インターロイキン-21ムテイン及び治療方法 |
JOP20200172A1 (ar) | 2018-01-12 | 2020-07-12 | Amgen Inc | الأجسام المضادة لـ pd-1 وطرق العلاج |
US11408840B2 (en) * | 2018-06-28 | 2022-08-09 | Just-Evotec Biologics, Inc. | High throughput interrogation of physiochemical properties of a protein |
CN115364209A (zh) * | 2021-05-20 | 2022-11-22 | 上海君实生物医药科技股份有限公司 | 抗pd-1抗体联合化疗治疗食管癌的用途 |
CN116687933A (zh) * | 2022-02-28 | 2023-09-05 | 中国科学院上海药物研究所 | 甲氨蝶呤及其药物组合物在肿瘤免疫治疗中的用途 |
WO2024054418A1 (en) * | 2022-09-08 | 2024-03-14 | Cugene Inc. | Sequence optimization of a pd1 blocking antibody |
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- 2017-09-08 EP EP17850229.0A patent/EP3514177B1/en active Active
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2021
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CN105566496A (zh) * | 2015-11-26 | 2016-05-11 | 大庆东竺明生物技术有限公司 | 阻断人程序性死亡因子1(pd-1)功能的单克隆抗体及其编码基因和应用 |
Cited By (1)
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WO2022148414A1 (zh) * | 2021-01-08 | 2022-07-14 | 北京韩美药品有限公司 | 特异性结合pd-l1的抗体及其抗原结合片段 |
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