CN109939040A - A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection - Google Patents
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection Download PDFInfo
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Abstract
The invention discloses a kind of Traditional Chinese medicinal hand lotions and preparation method thereof of pre- preventing germs infection; it is raw material that the Traditional Chinese medicinal hand lotion, which is by Chinese medicine composition extract and lauryl sodium sulfate, deionized water, lauroyl propylhomoserin sodium, Cocoamidopropyl betaine, potassium sorbate, citric acid, oil and fat of sacha inchi, essential oil, is aided with suitable auxiliary material and is prepared；It include following component: angelica extract, Herba Andrographitis alcohol extract, philippine flemingia root water extract, leatherleaf mahonia, single side needle water extract, cherokee rose root, Caulis Spatholobi, Radix Codonopsis water extract in the Chinese medicine composition extract；Inhibiting bacteria and diminishing inflammation Traditional Chinese medicinal hand lotion viscosity of the present invention is good, and foaming characteristic is good, strong detergency, it is good to rinse performance, and have inhibiting bacteria and diminishing inflammation effect, the pre- preventing germs infection of energy, and can nursing skin；The preparation method of Traditional Chinese medicinal hand lotion of the present invention is easy to operate, is with a wide range of applications.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, a kind of Traditional Chinese medicinal hand lotion more particularly, to pre- preventing germs infection and its
Preparation method.
Background technique
Promotion with people's living standard and the enhancing to health consciousness, China resident to the demand of hand cleanser not
It is disconnected to increase.Currently, hand cleanser has become the necessary article of people's daily life, product category is increasing, and progressively towards
Environmentally protective, functionalization, specially to change, the direction of seriation is developed.It is required in addition to the existing brand production in market meets general cleaning
Product outside, market product shows following several big types one after another: fragrance, natural, functional, special Xiang Huasi major class.But it is existing
The not creative quality for improving product of commercially available hand cleanser, hand cleanser has a single function, with chemical formulation class hand cleanser
In the majority, chemical formulation hand cleanser residual is strong, injures skin.
Currently, the type of germ is more, propagate fastly, many infectious diseases are caused by germ, especially winter, room ventilation
Effect is bad, and the spread speed of germ is especially fast, and especially the elderly, the chance of children's disease carrying germ are more, and germ infects
Enter the in the majority of respiratory tract by hand.
Therefore, consumer remained further need for one kind can pre- preventing germs infection and washability is good, faint scent, nontoxic secondary makees
Natural hand cleanser, during daily cleaning, energy inhibiting bacteria and diminishing inflammation prevents bacterial virus from invading body, prevents the hair of disease
It is raw.
In view of the above-mentioned problems, applicant Zhuzhou Qianjin Pharmacy Co., Ltd develops, one kind is environmentally protective, naturally may be used
It degrades, washing effect is good, inhibiting bacteria and diminishing inflammation, pre- preventing germs infection Traditional Chinese medicinal hand lotion.
Summary of the invention
The technical problem to be solved by the present invention is to for hand cleanser in the prior art do not have it is environmentally protective, do not have it is antibacterial
Anti-inflammatory, cannot pre- preventing germs infection the effect of, and the technical deficiency that using effect is bad, providing a kind of has inhibiting bacteria and diminishing inflammation, energy
The Traditional Chinese medicinal hand lotion of pre- preventing germs infection, solve hand cleanser in the prior art do not have it is environmentally protective, do not have inhibiting bacteria and diminishing inflammation,
Cannot pre- preventing germs infection the effect of, and the problem that using effect is bad.
Another technical problems to be solved of the present invention are to provide the preparation method of above-mentioned Traditional Chinese medicinal hand lotion.
The purpose of the present invention is achieved by the following technical programs:
A kind of Traditional Chinese medicinal hand lotion of pre- preventing germs infection is provided, the Traditional Chinese medicinal hand lotion is by Chinese medicine composition extract and ten
Sodium dialkyl sulfate, deionized water, lauroyl propylhomoserin sodium, Cocoamidopropyl betaine, potassium sorbate, citric acid, U.S. rattan
Fruit oil, essential oil are raw material, are aided with suitable auxiliary material and are prepared, the Chinese medicine composition extract includes following composition:
Angelica extract, Herba Andrographitis alcohol extract, philippine flemingia root water extract, leatherleaf mahonia, single side needle water extract, cherokee rose root, Caulis Spatholobi, Radix Codonopsis water
Extract.
Further, the Traditional Chinese medicinal hand lotion includes the raw material of following mass parts: 2~8 parts of Chinese medicine composition extract, ten
5~10 parts of sodium dialkyl sulfate, 60~75 parts of deionized water, 5~10 parts of lauroyl propylhomoserin sodium, Cocoamidopropyl betaine
5~10 parts, 1~2 part of potassium sorbate, 1~5 part of citric acid, 2~6 parts of oil and fat of sacha inchi, 0.1~0.5 part of essential oil.
Preferably, the Traditional Chinese medicinal hand lotion includes the raw material of following mass parts: 2~6 parts of Chinese medicine composition extract, 12
5~8 parts of sodium alkyl sulfate, 60~70 parts of deionized water, 5~8 parts of lauroyl propylhomoserin sodium, Cocoamidopropyl betaine 5~8
Part, 1~2 part of potassium sorbate, 1~3 part of citric acid, 4~5 parts of oil and fat of sacha inchi, 0.1~0.5 part of essential oil.
Preferably, the Traditional Chinese medicinal hand lotion includes the raw material of following mass parts: 4 parts of Chinese medicine composition extract, dodecane
6 parts of base sodium sulphate, 70 parts of deionized water, 6 parts of lauroyl propylhomoserin sodium, 6 parts of Cocoamidopropyl betaine, potassium sorbate 1.5
Part, 2 parts of citric acid, 4 parts of oil and fat of sacha inchi, 0.5 part of essential oil.
Further, the Chinese medicine composition extract includes the ingredient of following mass parts: 8~10 parts of angelica extract,
8~10 parts of Herba Andrographitis alcohol extract, 12~18 parts of philippine flemingia root water extract, leatherleaf mahonia, 20~30 parts of single side needle water extract, cherokee rose root,
35~45 parts of Caulis Spatholobi, Radix Codonopsis water extract.
Preferably, the Chinese medicine composition extract includes the ingredient of following mass parts: 9 parts of angelica extract, Herba Andrographitis
9 parts of alcohol extract, 16 parts of philippine flemingia root water extract, leatherleaf mahonia, 25 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi, Radix Codonopsis water extract 41
Part.
Further, the leatherleaf mahonia, in single side needle water extract, the mass ratio of each ingredient are as follows: 14~18:8~10, it is described
During cherokee rose root, Caulis Spatholobi, Radix Codonopsis water extract, the mass ratio of each ingredient are as follows: 14~18:14~18:8~10.
Preferably, the leatherleaf mahonia, in single side needle water extract, the mass ratio of each ingredient is 16:9, the cherokee rose root, chicken blood
During rattan, Radix Codonopsis water extract, the mass ratio of each ingredient are as follows: 16:16:9.
Preferably, the citric acid is the citric acid being added after deionized water dissolving, and the mass concentration of the citric acid is
20~40%.
Preferably, the mass concentration of the citric acid is 30%.
Further, the Traditional Chinese medicinal hand lotion preparation method the following steps are included:
S1. the preparation of Chinese medicine composition extract, it is described preparation the following steps are included:
S11. clear cream is made with 70~85% ethanol percolation in the Radix Angelicae Sinensis for choosing formula ratio, obtains angelica extract, filter residue
It is spare；
S12. the Herba Andrographitis for choosing formula ratio is extracted with 70~85% alcohol reflux, recycles ethyl alcohol, and filtrate is condensed into clearly
Cream, obtains Andrographis Paniculata, and filter residue is spare；
S13. the philippine flemingia root for choosing formula ratio is decocted 2 times with water, and each water consumption is 4~10 times of philippine flemingia root weight, is decocted
Boiling the time is 2~4 hours, filters collecting decoction, and filtration, relative density is 1.08~1.12 when filtrate is concentrated into 80 DEG C, obtains thousand
Jin pulls out water extract；
S14. leatherleaf mahonia, the single side needle for choosing formula ratio in proportion, are decocted 2 times with water, and water consumption is two taste Chinese medicine gross weights
8~10 times of amounts of amount, decocting time are 2~3 hours, and collecting decoction, filtration, relative density is 1.08 when filtrate is concentrated into 80 DEG C
~1.12, obtain leatherleaf mahonia, single side needle water extract；
S15. cherokee rose root, Caulis Spatholobi, the Radix Codonopsis for choosing formula ratio in proportion, are decocted 2 times with water, add three taste Chinese medicines for the first time
The water of 4~10 times of total weight amounts, the dregs of a decoction after extracting for the first time add the resulting Radix Angelicae Sinensis of S11, S12, the Herba Andrographitis dregs of a decoction to decoct 2 together
Hour, amount of water is 4~10 times of amounts of traditional Chinese medicine of the five flavours total weight, and collecting decoction filters, and filtrate merges concentration, obtains cherokee rose root, chicken
Blood rattan, Radix Codonopsis water extract；
S16. above-mentioned five kinds of extracts mixed in proportion, be watered dissolution, make the water content 20~35% of extract, i.e.,
Obtain Chinese medicine composition extract.
S2. the preparation of Traditional Chinese medicinal hand lotion, it is described preparation the following steps are included:
S21. lauryl sodium sulfate, deionized water are proportionally added into, are heated to 60~80 DEG C, stir evenly, until complete
It is complete miscible；
S22. lauroyl propylhomoserin sodium, Cocoamidopropyl betaine are proportionally added into S21 products therefrom, at a slow speed
It stirs evenly, stops heating, placement is cooled to 40~50 DEG C, is proportionally added into Chinese medicine composition extract, the sorb of S1 preparation
Sour potassium stirs to clarify；
S23. citric acid is dissolved in deionized water, the citric acid that mass concentration is 20~40% is configured to, to S22 institute
After obtaining product cooling, citric acid is added by formula rate, is stirring evenly and then adding into oil and fat of sacha inchi, it is sufficiently molten to all substances
After solution, essential oil is added dropwise, stirs evenly at a slow speed to get hand cleanser of the present invention.
The invention has the following advantages:
1, the Chinese medicine composition extract in product of the present invention and the mutual compatibility of other compositions, optimum organization, so that preparation
Product viscosity it is good, foaming characteristic is good, strong detergency, rinse performance is good, wash after can nursing skin, and have inhibiting bacteria and diminishing inflammation, pre-
The effect of preventing germs infection.
2, main inhibiting bacteria and diminishing inflammation ingredient in product of the present invention is Chinese medicine composition extract, and inventor's Accurate Analysis should
Main component and its interaction in composition material, Radix Angelicae Sinensis are extracted using ethanol percolation, greatly protect Radix Angelicae Sinensis
In effective component, Herba Andrographitis using alcohol reflux extract, inhibiting bacteria and diminishing inflammation effective component andrographolide therein and dehydration wear
Heart lotus lactone can extract to the greatest extent, and the independent water of philippine flemingia root mentions, main inhibiting bacteria and diminishing inflammation ingredient genistin and dyestuff
Lignin quickly, can be extracted adequately, and leatherleaf mahonia, the combination of single side needle are extracted, other three kinds of medicinal materials combinations are extracted so that respectively at
/ mutually synergy, an antibacterial, antiphlogistic activity significantly increases, with other compositions compatible use in hand cleanser, can both resist
Bacterium anti-inflammatory, when product use, have cleaning, comfortable, health-care and skin-care effect again.
3, the raw material in the present invention is natural materials or extracts from Chinese medicine, is not added with synthesis chemical component, uses
When soft touch, washability is good, and to skin without any stimulation, including hand injury skin can be used, using in injury
It, can not only be to wound inhibiting bacteria and diminishing inflammation, moreover it is possible to wound be promoted to heal as early as possible when on skin.
Meanwhile after this product use, there are natural Chinese medicine faint scent for hand, then cooperate with the essential oil of addition, so that product
Fragrance more faint scent it is pleasant.
4, traditional Chinese medicine composition extract liquid of the present invention and hand cleanser long shelf-life, stability is high, and inhibiting bacteria and diminishing inflammation effect is held
Long, it cannot be only used in hand cleanser, it may also be used in other cleaning products.
5, the raw material that product of the present invention uses is easy to get, and preparation method is easy, environmentally protective, is suitable for large-scale production,
It has a good application prospect.
6, tests prove that, product of the present invention, the significant effect in inhibiting bacteria and diminishing inflammation effect.
Specific embodiment
Further illustrate the present invention below in conjunction with specific embodiment, but embodiment the present invention is not done it is any type of
It limits.Unless stated otherwise, the present invention uses reagent, method and apparatus is the art conventional reagents, method and apparatus.
Unless stated otherwise, following embodiment agents useful for same and material are commercially available.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection of embodiment 1
(1) be formulated: in raw material include following mass component: 4 parts of Chinese medicine composition extract, 6 parts of lauryl sodium sulfate,
70 parts of deionized water, 6 parts of lauroyl propylhomoserin sodium, 6 parts of Cocoamidopropyl betaine, 1.5 parts of potassium sorbate, 2 parts of citric acid,
4 parts of oil and fat of sacha inchi, 0.5 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: angelica extract 9
Part, 9 parts of Herba Andrographitis alcohol extract, 16 parts of philippine flemingia root water extract, leatherleaf mahonia, 25 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi, party
41 parts of water extract of ginseng；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 16:9, the gold cherry
Root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 16:16:9, and the citric acid is after deionized water dissolving is added
Citric acid.
(2) preparation method:
S1. the preparation of Chinese medicine composition extract, it is described preparation the following steps are included:
S11. clear cream is made with 80% ethanol percolation in the Radix Angelicae Sinensis for choosing formula ratio, obtains angelica extract, filter residue is spare；
S12. the Herba Andrographitis for choosing formula ratio is extracted with 80% alcohol reflux, recycles ethyl alcohol, and filtrate is condensed into clear cream,
Andrographis Paniculata is obtained, filter residue is spare；
S13. the philippine flemingia root for choosing formula ratio is decocted 2 times with water, and each water consumption is 8 times of philippine flemingia root weight, when decoction
Between be 3 hours, filter collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~1.12, obtain philippine flemingia root water and mention
Object；
S14. leatherleaf mahonia, the single side needle for choosing formula ratio in proportion, are decocted 2 times with water, and water consumption is two taste Chinese medicine gross weights
Amount 9 times amount, decocting time be 2.5 hours, collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~
1.12, obtain leatherleaf mahonia, single side needle water extract；
S15. cherokee rose root, Caulis Spatholobi, the Radix Codonopsis for choosing formula ratio in proportion, are decocted 2 times with water, add three taste Chinese medicines for the first time
The water of 8 times of total weight amounts, the dregs of a decoction after extracting for the first time add that the resulting Radix Angelicae Sinensis of S11, S12, that the Herba Andrographitis dregs of a decoction decoct 2 together is small
When, amount of water is 8 times of traditional Chinese medicine of the five flavours total weight amounts, collecting decoction, filtration, and filtrate merges concentration, obtain cherokee rose root, Caulis Spatholobi,
Radix Codonopsis water extract；
S16. above-mentioned five kinds of extracts mixed in proportion, be watered dissolution, make the water content 30% of extract to get in
Drug composition extract.
S2. the preparation of Traditional Chinese medicinal hand lotion, it is described preparation the following steps are included:
S21. lauryl sodium sulfate, deionized water are proportionally added into, are heated to 70 DEG C, stir evenly, until completely mixed
It is molten；
S22. lauroyl propylhomoserin sodium, Cocoamidopropyl betaine are proportionally added into S21 products therefrom, at a slow speed
It stirs evenly, stops heating, placement is cooled to 45 DEG C, is proportionally added into Chinese medicine composition extract, the potassium sorbate of S1 preparation
It stirs to clarify；
S23. citric acid is dissolved in deionized water, is configured to the citric acid that mass concentration is 30%, to be produced obtained by S22
After object is cooling, citric acid is added by formula rate, is stirring evenly and then adding into oil and fat of sacha inchi, sufficiently dissolves it to all substances
Afterwards, essential oil is added dropwise, stirs evenly at a slow speed to get hand cleanser of the present invention.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection of embodiment 2
(1) be formulated: in raw material include following mass component: 2 parts of Chinese medicine composition extract, 5 parts of lauryl sodium sulfate,
60 parts of deionized water, 10 parts of lauroyl propylhomoserin sodium, 10 parts of Cocoamidopropyl betaine, 2 parts of potassium sorbate, 5 parts of citric acid,
5.9 parts of oil and fat of sacha inchi, 0.1 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: angelica extract
8 parts, 8 parts of Herba Andrographitis alcohol extract, 12 parts of philippine flemingia root water extract, leatherleaf mahonia, 30 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi, party
42 parts of water extract of ginseng；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 14:10, the gold cherry
Root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 14:14:8, and the citric acid is after deionized water dissolving is added
Citric acid.
(2) preparation method:
S1. the preparation of Chinese medicine composition extract, it is described preparation the following steps are included:
S11. clear cream is made with 70% ethanol percolation in the Radix Angelicae Sinensis for choosing formula ratio, obtains angelica extract, filter residue is spare；
S12. the Herba Andrographitis for choosing formula ratio is extracted with 70% alcohol reflux, recycles ethyl alcohol, and filtrate is condensed into clear cream,
Andrographis Paniculata is obtained, filter residue is spare；
S13. the philippine flemingia root for choosing formula ratio is decocted 2 times with water, and each water consumption is 4 times of philippine flemingia root weight, when decoction
Between be 4 hours, filter collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~1.12, obtain philippine flemingia root water and mention
Object；
S14. leatherleaf mahonia, the single side needle for choosing formula ratio in proportion, are decocted 2 times with water, and water consumption is two taste Chinese medicine gross weights
8 times of amounts of amount, decocting time are 3 hours, and collecting decoction, filtration, relative density is 1.08~1.12 when filtrate is concentrated into 80 DEG C,
Obtain leatherleaf mahonia, single side needle water extract；
S15. cherokee rose root, Caulis Spatholobi, the Radix Codonopsis for choosing formula ratio in proportion, are decocted 2 times with water, add three taste Chinese medicines for the first time
The water of 4 times of total weight amounts, the dregs of a decoction after extracting for the first time add that the resulting Radix Angelicae Sinensis of S11, S12, that the Herba Andrographitis dregs of a decoction decoct 2 together is small
When, amount of water is 4 times of traditional Chinese medicine of the five flavours total weight amounts, collecting decoction, filtration, and filtrate merges concentration, obtain cherokee rose root, Caulis Spatholobi,
Radix Codonopsis water extract；
S16. above-mentioned five kinds of extracts mixed in proportion, be watered dissolution, make the water content 20% of extract to get in
Drug composition extract.
S2. the preparation of Traditional Chinese medicinal hand lotion, it is described preparation the following steps are included:
S21. lauryl sodium sulfate, deionized water are proportionally added into, are heated to 60 DEG C, stir evenly, until completely mixed
It is molten；
S22. lauroyl propylhomoserin sodium, Cocoamidopropyl betaine are proportionally added into S21 products therefrom, at a slow speed
It stirs evenly, stops heating, placement is cooled to 40 DEG C, is proportionally added into Chinese medicine composition extract, the potassium sorbate of S1 preparation
It stirs to clarify；
S23. citric acid is dissolved in deionized water, is configured to the citric acid that mass concentration is 20%, to be produced obtained by S22
After object is cooling, citric acid is added by formula rate, is stirring evenly and then adding into oil and fat of sacha inchi, sufficiently dissolves it to all substances
Afterwards, essential oil is added dropwise, stirs evenly at a slow speed to get hand cleanser of the present invention.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection of embodiment 3
(1) be formulated: in raw material include following mass component: 6 parts of Chinese medicine composition extract, 8 parts of lauryl sodium sulfate,
60 parts of deionized water, 10 parts of lauroyl propylhomoserin sodium, 10 parts of Cocoamidopropyl betaine, 2 parts of potassium sorbate, 1 part of citric acid,
2.5 parts of oil and fat of sacha inchi, 0.5 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: angelica extract
10 parts, 10 parts of Herba Andrographitis alcohol extract, 18 parts of philippine flemingia root water extract, leatherleaf mahonia, 20 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi,
42 parts of Radix Codonopsis water extract；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 18:8, the gold
Cherry root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 14:18:10, and the citric acid is that deionization is added is water-soluble
Citric acid after solution.
(2) preparation method:
S1. the preparation of Chinese medicine composition extract, it is described preparation the following steps are included:
S11. clear cream is made with 85% ethanol percolation in the Radix Angelicae Sinensis for choosing formula ratio, obtains angelica extract, filter residue is spare；
S12. the Herba Andrographitis for choosing formula ratio is extracted with 85% alcohol reflux, recycles ethyl alcohol, and filtrate is condensed into clear cream,
Andrographis Paniculata is obtained, filter residue is spare；
S13. the philippine flemingia root for choosing formula ratio is decocted 2 times with water, and each water consumption is 10 times of philippine flemingia root weight, when decoction
Between be 2 hours, filter collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~1.12, obtain philippine flemingia root water and mention
Object；
S14. leatherleaf mahonia, the single side needle for choosing formula ratio in proportion, are decocted 2 times with water, and water consumption is two taste Chinese medicine gross weights
Amount 10 times amount, decocting time be 2 hours, collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~
1.12, obtain leatherleaf mahonia, single side needle water extract；
S15. cherokee rose root, Caulis Spatholobi, the Radix Codonopsis for choosing formula ratio in proportion, are decocted 2 times with water, add three taste Chinese medicines for the first time
The water of 10 times of total weight amounts, the dregs of a decoction after extracting for the first time add that the resulting Radix Angelicae Sinensis of S11, S12, that the Herba Andrographitis dregs of a decoction decoct 2 together is small
When, amount of water is 10 times of traditional Chinese medicine of the five flavours total weight amounts, collecting decoction, filtration, and filtrate merges concentration, obtain cherokee rose root, Caulis Spatholobi,
Radix Codonopsis water extract；
S16. above-mentioned five kinds of extracts mixed in proportion, be watered dissolution, make the water content 35% of extract to get in
Drug composition extract.
S2. the preparation of Traditional Chinese medicinal hand lotion, it is described preparation the following steps are included:
S21. lauryl sodium sulfate, deionized water are proportionally added into, are heated to 80 DEG C, stir evenly, until completely mixed
It is molten；
S22. lauroyl propylhomoserin sodium, Cocoamidopropyl betaine are proportionally added into S21 products therefrom, at a slow speed
It stirs evenly, stops heating, placement is cooled to 50 DEG C, is proportionally added into Chinese medicine composition extract, the potassium sorbate of S1 preparation
It stirs to clarify；
S23. citric acid is dissolved in deionized water, is configured to the citric acid that mass concentration is 40%, to be produced obtained by S22
After object is cooling, citric acid is added by formula rate, is stirring evenly and then adding into oil and fat of sacha inchi, sufficiently dissolves it to all substances
Afterwards, essential oil is added dropwise, stirs evenly at a slow speed to get hand cleanser of the present invention.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection of embodiment 4
(1) it is formulated: including following mass component: 8 parts of Chinese medicine composition extract, lauryl sodium sulfate 10 in raw material
Part, 60 parts of deionized water, 5 parts of lauroyl propylhomoserin sodium, 8 parts of Cocoamidopropyl betaine, 1 part of potassium sorbate, citric acid 3
Part, 4.9 parts of oil and fat of sacha inchi, 0.1 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: Radix Angelicae Sinensis mentions
Take 8 parts of object, 10 parts of Herba Andrographitis alcohol extract, 18 parts of philippine flemingia root water extract, leatherleaf mahonia, 29 parts of single side needle water extract, cherokee rose root, chicken blood
35 parts of rattan, Radix Codonopsis water extract；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 18:10, institute
State cherokee rose root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 18:14:8, and the citric acid is that deionized water is added
Dissolved citric acid.
(2) preparation method:
S1. the preparation of Chinese medicine composition extract, it is described preparation the following steps are included:
S11. clear cream is made with 75% ethanol percolation in the Radix Angelicae Sinensis for choosing formula ratio, obtains angelica extract, filter residue is spare；
S12. the Herba Andrographitis for choosing formula ratio is extracted with 75% alcohol reflux, recycles ethyl alcohol, and filtrate is condensed into clear cream,
Andrographis Paniculata is obtained, filter residue is spare；
S13. the philippine flemingia root for choosing formula ratio is decocted 2 times with water, and each water consumption is 6 times of philippine flemingia root weight, when decoction
Between be 2 hours, filter collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~1.12, obtain philippine flemingia root water and mention
Object；
S14. leatherleaf mahonia, the single side needle for choosing formula ratio in proportion, are decocted 2 times with water, and water consumption is two taste Chinese medicine gross weights
9 times of amounts of amount, decocting time are 3 hours, and collecting decoction, filtration, relative density is 1.08~1.12 when filtrate is concentrated into 80 DEG C,
Obtain leatherleaf mahonia, single side needle water extract；
S15. cherokee rose root, Caulis Spatholobi, the Radix Codonopsis for choosing formula ratio in proportion, are decocted 2 times with water, add three taste Chinese medicines for the first time
The water of 6 times of total weight amounts, the dregs of a decoction after extracting for the first time add that the resulting Radix Angelicae Sinensis of S11, S12, that the Herba Andrographitis dregs of a decoction decoct 2 together is small
When, amount of water is 6 times of traditional Chinese medicine of the five flavours total weight amounts, collecting decoction, filtration, and filtrate merges concentration, obtain cherokee rose root, Caulis Spatholobi,
Radix Codonopsis water extract；
S16. above-mentioned five kinds of extracts mixed in proportion, be watered dissolution, make the water content 25% of extract to get in
Drug composition extract.
S2. the preparation of Traditional Chinese medicinal hand lotion, it is described preparation the following steps are included:
S21. lauryl sodium sulfate, deionized water are proportionally added into, are heated to 65 DEG C, stir evenly, until completely mixed
It is molten；
S22. lauroyl propylhomoserin sodium, Cocoamidopropyl betaine are proportionally added into S21 products therefrom, at a slow speed
It stirs evenly, stops heating, placement is cooled to 45 DEG C, is proportionally added into Chinese medicine composition extract, the potassium sorbate of S1 preparation
It stirs to clarify；
S23. citric acid is dissolved in deionized water, is configured to the citric acid that mass concentration is 35%, to be produced obtained by S22
After object is cooling, citric acid is added by formula rate, is stirring evenly and then adding into oil and fat of sacha inchi, sufficiently dissolves it to all substances
Afterwards, essential oil is added dropwise, stirs evenly at a slow speed to get hand cleanser of the present invention.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection of embodiment 5
(1) it is formulated: including following mass component: 2 parts of Chinese medicine composition extract, lauryl sodium sulfate 5.8 in raw material
Part, 75 parts of deionized water, 8 parts of lauroyl propylhomoserin sodium, 5 parts of Cocoamidopropyl betaine, 1 part of potassium sorbate, citric acid 1
Part, 2 parts of oil and fat of sacha inchi, 0.2 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: Radix Angelicae Sinensis extracts
10 parts of object, 10 parts of Herba Andrographitis alcohol extract, 15 parts of philippine flemingia root water extract, leatherleaf mahonia, 20 parts of single side needle water extract, cherokee rose root, chicken blood
45 parts of rattan, Radix Codonopsis water extract；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 15:9, described
Cherokee rose root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 15:15:9, and the citric acid is that deionization is added is water-soluble
Citric acid after solution.
(2) preparation method: with embodiment 1.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing virus infection of embodiment 6
(1) be formulated: in raw material include following mass component: 8 parts of Chinese medicine composition extract, 5 parts of lauryl sodium sulfate,
65 parts of deionized water, 5 parts of lauroyl propylhomoserin sodium, 5 parts of Cocoamidopropyl betaine, 2.7 parts of potassium sorbate, 3 parts of citric acid,
6 parts of oil and fat of sacha inchi, 0.3 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: angelica extract 8
Part, 9 parts of Herba Andrographitis alcohol extract, 16 parts of philippine flemingia root water extract, leatherleaf mahonia, 25 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi, party
42 parts of water extract of ginseng；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 17:8, the gold cherry
Root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 17:16:9, and the citric acid is after deionized water dissolving is added
Citric acid.
(2) preparation method: with embodiment 1.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection of embodiment 7
(1) be formulated: in raw material include following mass component: 4 parts of Chinese medicine composition extract, 6 parts of lauryl sodium sulfate,
70 parts of deionized water, 6 parts of lauroyl propylhomoserin sodium, 6 parts of Cocoamidopropyl betaine, 1.5 parts of potassium sorbate, 1 part of citric acid,
5 parts of oil and fat of sacha inchi, 0.5 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: angelica extract 9
Part, 9 parts of Herba Andrographitis alcohol extract, 16 parts of philippine flemingia root water extract, leatherleaf mahonia, 21 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi, party
45 parts of water extract of ginseng；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 14:8, the gold cherry
Root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 14:14:10, and the citric acid is that deionized water dissolving is added
Citric acid afterwards.
(2) preparation method: with embodiment 1.
A kind of Traditional Chinese medicinal hand lotion and preparation method thereof of pre- preventing germs infection of embodiment 8
(1) be formulated: in raw material include following mass component: 4 parts of Chinese medicine composition extract, 6 parts of lauryl sodium sulfate,
70 parts of deionized water, 6 parts of lauroyl propylhomoserin sodium, 6 parts of Cocoamidopropyl betaine, 1.5 parts of potassium sorbate, 2 parts of citric acid,
4 parts of oil and fat of sacha inchi, 0.5 part of essential oil；The mass parts of each ingredient in the Chinese medicine composition extract are as follows: angelica extract 9
Part, 9 parts of Herba Andrographitis alcohol extract, 16 parts of philippine flemingia root water extract, leatherleaf mahonia, 25 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi, party
41 parts of water extract of ginseng；In the leatherleaf mahonia, single side needle water extract, the mass ratio of leatherleaf mahonia and single side needle is 16:9, the gold cherry
Root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient is 16:16:9, and the citric acid is after deionized water dissolving is added
Citric acid；The angelica extract, Herba Andrographitis alcohol extract, the extraction of philippine flemingia root water are to buy commercial product, the leatherleaf mahonia,
The extraction of single side needle water is the commercially available leatherleaf mahonia water extract of purchase, single side needle water extract, then is deployed in proportion, the cherokee rose root,
Caulis Spatholobi, Radix Codonopsis water extract be the commercially available cherokee rose root water extract of purchase, Aqueous Extracts From Caulis Spatholobi, Radix Codonopsis water extract deploy in proportion again and
At.
(2) preparation method:
S1. the preparation of Chinese medicine composition extract, it is described preparation the following steps are included:
S11. leatherleaf mahonia water extract, single side needle water extract are chosen in proportion, are deployed into leatherleaf mahonia, single side needle mixing water mentions
Object, it is spare；
S12. cherokee rose root water extract, Aqueous Extracts From Caulis Spatholobi, Radix Codonopsis water extract are chosen in proportion, are deployed into cherokee rose root, chicken blood
Rattan, Radix Codonopsis mixing water extract, it is spare；
S13. the water extract that will be deployed in S11 and S12, in proportion with angelica extract, Herba Andrographitis alcohol extract, philippine flemingia root water
Extract allotment, is made Chinese medicine composition extract, makes its water content 30%.
S2. the preparation method of Traditional Chinese medicinal hand lotion: with embodiment 1
The experiment of 9 microbiological indicator of experimental example
Microbial indicators detected is carried out to the hand cleanser that the preparation method of Examples 1 to 8 obtains, according to the country of hand cleanser
Standard GB 19877.1-2005 is measured.It the results are shown in Table 1.
The microorganism detection index number of 1 different experiments group hand cleanser of table
| Total plate count, CFU/g | Excrement colibacillus group | |
| Embodiment 1 | 17 | 0 |
| Embodiment 2 | 19 | 0 |
| Embodiment 3 | 20 | 0 |
| Embodiment 4 | 19 | 0 |
| Embodiment 5 | 21 | 0 |
| Embodiment 6 | 20 | 0 |
| Embodiment 7 | 23 | 0 |
| Embodiment 8 | 49 | 0 |
From above-mentioned table data can be seen that inhibiting bacteria and diminishing inflammation hand cleanser of the present invention microorganism detection content it is extremely low,
The content of microorganisms of significantly larger than national standard, embodiment 8 is slightly above Examples 1 to 7, may be with Chinese traditional medicine composition in embodiment 8
Raw material in object is that purchase commercial product is related.
The experiment on probation of 10 product effect of experimental example
On December 20th, 2016 sample is deployed according to the method for the embodiment of the present invention 1, embodiment 4, embodiment 8, is in addition purchased
On the market fast-selling a hand cleanser group as a comparison case is bought, fragrance is carried out to experimental group sample, rear skin comfort degree is washed and touches
Rope experiment.Select 100 consumers to form evaluation group as evaluating member, it is desirable that evaluating member before evaluation hand without it is injured,
Without decortication situation, collection evaluation form is for statistical analysis, as a result see the table below 2:
The fragrance of 2 different experiments group hand cleanser of table and wash rear Comfort Evaluation
User's result on trial shows: hand cleanser products pleasant aroma of the present invention, washes rear skin comfort, and effect is better than comparative example
Group.
11 skin irritation test of experimental example
By taking inhibiting bacteria and diminishing inflammation hand cleanser prepared by the method for Examples 1 to 8 as an example, inhibiting bacteria and diminishing inflammation hand cleanser is observed to skin
Irritation and allergic reaction provide reference to evaluate its safety.
(1) skin irritation test is carried out using rabbit, divides intact skin group and damage skin group, for 24 hours by rabbit before test
Back backbone diamond wool shaves off, and is kept in contact respectively with hand cleanser prepared by the embodiment of the present invention 1~8 with rabbit skin and mucosa
After 1d, continuous 7d, whether there is or not the stimulate the reactions such as erythema, oedema for observation skin.
(2) skin allergy experiment is carried out using cavy, weekly the hand cleanser with the preparation of the embodiment of the present invention 1~8 and cavy
Skin and mucosa is kept in contact 2 times, contacts 4h or more every time, continuous 3 weeks, whether there is or not the allergic reactions such as erythema, oedema for observation skin.
Experimental result:
The intact skin and damaged skin of rabbit, remove after being intended for single use or be used for multiple times for 24 hours, respectively at 1,24,48,
72h observation, is showed no erythema and oedema, and stimulate the reaction mean scores are < 0.5, nonirritant.
In guinea pig skin allergic experiment, does not occur the cutaneous anaphylaxises such as the obvious erythema of skin, oedema and other are systemic
Allergic reaction.
Therefore, inhibiting bacteria and diminishing inflammation hand cleanser of the invention will not cause irritation anti-rabbit intact skin and damage skin
It answers, to guinea pig skin without allergic reaction, there is good cutaneous safety.
12 bacteriostatic experiment of experimental example
Body is carried out to the inhibiting bacteria and diminishing inflammation hand cleanser and commercially available common hand cleanser (control group) of the method preparation of Examples 1 to 8
Outer bacteriostatic test.
1. materials and methods
The 0.03mol/L phosphate buffer (PBS) of the preparation of 1.1 bacteria suspensions peptone containing 10g/L, will be golden yellow
Fresh cultured object inclined-plane lawn is washed for 24 hours for staphylococcus (ATCC6538), Escherichia coli (8099), Pseudomonas aeruginosa (ATCC9027)
Under, then diluted with PBS and be made into bacteria suspension.
1.2 bacteriostatic tests choose inhibiting bacteria and diminishing inflammation hand cleanser ingredient (8 groups of example 1 group~embodiment) of the present invention, it is commercially available not
Hand cleanser (control group) containing antipathogenic composition.Qualitative filter paper is made to the disk of diameter 5mm, after pressuresteam sterilization is handled,
120 DEG C of dry 2h are set, it is spare.It takes the filter paper handled well to be put into sterilized petri dishes (4 one folded), about 20 μ l is added dropwise respectively and respectively wash
Hand liquid stoste is to filter paper, and as test print, negative control print is added dropwise 20 μ l sterile distilled waters, dries spare.With sterile
Cotton swab dips above-mentioned test bacteria suspension and is uniformly applied to nutrient agar planar surface respectively, sets drying at room temperature 5min.
Test print is placed on microbiological contamination plate, each plate is placed with 4 test prints and 1 negative control print totally 5.Each print
At a distance of 25mm or more between center, the periphery with plate tests 1 plate at a distance of 15mm or more every time.After being placed with, 37 DEG C are set
Incubator 16~18h of culture, observation is as a result, measure the diameter (including patch) of antibacterial ring size, and record measurement data.Experiment repeats 3
It is secondary.Inhibition zone diameter > 7mm person has been judged to bacteriostasis, and≤7mm person is judged to no bacteriostasis, and 3 repetition tests, which reach, suppression
Bacterium exercising result person, is judged to qualification.Negative control group should be generated without antibacterial ring size, and otherwise test is invalid.
2 results
2.1 bacteriostatic tests are from bacteriostatic test result (table 3) as can be seen that hand cleanser stoste example 1 group~reality of the present invention
Applying 8 groups of example has certain inhibiting effect to Escherichia coli, staphylococcus aureus and Pseudomonas aeruginosa, and wherein example 1 group is washed
Hand liquid fungistatic effect is best, and 8 groups of hand cleanser fungistatic effects of embodiment are poor, and control group hand cleanser to 3 kinds of bacteriums without antibacterial effect
Fruit.
Bacteriostatic diameter (mm) of the 3 different experiments group hand cleanser of table to different bacterium
The result shows that: the hand cleanser of the embodiment of the present invention 1~8 has preferable bacteriostatic activity, washing compared to the control group
Hand liquid has significant advantage.
The experiment of 13 clinical use of experimental example
Using the inhibiting bacteria and diminishing inflammation hand cleanser of embodiment 1,4,8 as experimental material, as a control group with commercially available common hand cleanser, choosing
Selecting hand has adult totally 200 people, the age-based layer of slight wound to be randomly divided into 4 groups, and every group of 50 people are cleaned 5 times with swab stick daily,
After 3 days, detects inhibiting bacteria and diminishing inflammation hand cleanser provided by the invention and unite to the anti-inflammatory situation of wound, and to its experimental result
Meter.It the results are shown in Table 4.
Anti-inflammatory situation of the 4 different experiments group hand cleanser of table to wound location
As the result is shown: having 15 in control group using there is stimulate the reaction after the product of control group, and wound is occurred
Stimulation do not occur for phenomenon of festering (account for total number of persons 30%), embodiment 1, embodiment 4 and wound festers reaction in embodiment 8.
As it can be seen that inhibiting bacteria and diminishing inflammation hand cleanser provided by the invention to wound skin without any irritation and side effect, and have anti-inflammatory effects.
Detailed process equipment and processing step of the invention that the present invention is explained by the above embodiments, those skilled in the art
Member is not it should be appreciated that the present invention is limited by above-described embodiment, and the above embodiments and description only describe the present invention
Principle, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, this is to this field
It is it will be apparent that these changes and improvements all fall within the protetion scope of the claimed invention for technical staff.
Claims (10)
1. a kind of Traditional Chinese medicinal hand lotion of pre- preventing germs infection, which is characterized in that the Traditional Chinese medicinal hand lotion is extracted by Chinese medicine composition
Object and lauryl sodium sulfate, deionized water, lauroyl propylhomoserin sodium, Cocoamidopropyl betaine, potassium sorbate, lemon
Acid, oil and fat of sacha inchi, essential oil are raw material, are aided with suitable auxiliary material and are prepared；Include in the Chinese medicine composition extract
Following component: angelica extract, Herba Andrographitis alcohol extract, philippine flemingia root water extract, leatherleaf mahonia, single side needle water extract, cherokee rose root, chicken blood
Rattan, Radix Codonopsis water extract.
2. Traditional Chinese medicinal hand lotion according to claim 1, which is characterized in that the Traditional Chinese medicinal hand lotion includes following mass parts
Raw material: 2~8 parts of Chinese medicine composition extract, 5~10 parts of lauryl sodium sulfate, 60~75 parts of deionized water, lauroyl ammonia
5~10 parts of sour sodium, 5~10 parts of Cocoamidopropyl betaine, 1~2 part of potassium sorbate, 1~5 part of citric acid, oil and fat of sacha inchi 2~
6 parts, 0.1~0.5 part of essential oil.
3. Traditional Chinese medicinal hand lotion according to claim 2, which is characterized in that the Traditional Chinese medicinal hand lotion includes following mass parts
Raw material: 2~6 parts of Chinese medicine composition extract, 5~8 parts of lauryl sodium sulfate, 60~70 parts of deionized water, lauroyl ammonia
5~8 parts of sour sodium, 5~8 parts of Cocoamidopropyl betaine, 1~2 part of potassium sorbate, 1~3 part of citric acid, oil and fat of sacha inchi 4~5
Part, 0.1~0.5 part of essential oil.
4. Traditional Chinese medicinal hand lotion according to claim 2, which is characterized in that the Traditional Chinese medicinal hand lotion includes following mass parts
Raw material: 4 parts of Chinese medicine composition extract, 6 parts of lauryl sodium sulfate, 70 parts of deionized water, 6 parts of lauroyl propylhomoserin sodium, coconut palm
6 parts of oleamide propyl betaine, 1.5 parts of potassium sorbate, 2 parts of citric acid, 4 parts of oil and fat of sacha inchi, 0.5 part of essential oil.
5. Traditional Chinese medicinal hand lotion according to any one of claims 1 to 4, which is characterized in that the Chinese medicine composition extract packet
Include the ingredient of following mass parts: 8~10 parts of angelica extract, 8~10 parts of Herba Andrographitis alcohol extract, philippine flemingia root water extract 12~18
Part, leatherleaf mahonia, 20~30 parts of single side needle water extract, cherokee rose root, Caulis Spatholobi, 35~45 parts of Radix Codonopsis water extract.
6. Traditional Chinese medicinal hand lotion according to claim 5, which is characterized in that the Chinese medicine composition extract includes following matter
The ingredient of amount part: 9 parts of angelica extract, 9 parts of Herba Andrographitis alcohol extract, 16 parts of philippine flemingia root water extract, leatherleaf mahonia, single side needle water extract
25 parts, cherokee rose root, Caulis Spatholobi, 41 parts of Radix Codonopsis water extract.
7. Traditional Chinese medicinal hand lotion according to claim 5, which is characterized in that in the leatherleaf mahonia, single side needle water extract, respectively at
Point mass ratio are as follows: 14~18:8~10, the cherokee rose root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient are as follows: 14
~18:14~18:8~10.
8. Traditional Chinese medicinal hand lotion according to claim 5, which is characterized in that in the leatherleaf mahonia, single side needle water extract, respectively at
Point mass ratio be 16:9, the cherokee rose root, Caulis Spatholobi, in Radix Codonopsis water extract, the mass ratio of each ingredient are as follows: 16:16:9.
9. according to claim 1~4,6~8 any Traditional Chinese medicinal hand lotion, which is characterized in that the citric acid is to be added to go
The dissolved citric acid of ionized water, the mass concentration of the citric acid are 20~40%；The mass concentration of the citric acid is preferably
30%。
10. according to claim 1~4,6~8 any Traditional Chinese medicinal hand lotion, which is characterized in that the Traditional Chinese medicinal hand lotion
Preparation method the following steps are included:
S1. the preparation of Chinese medicine composition extract, it is described preparation the following steps are included:
S11. clear cream is made with 70~85% ethanol percolation in the Radix Angelicae Sinensis for choosing formula ratio, obtains angelica extract, filter residue is spare；
S12. the Herba Andrographitis for choosing formula ratio is extracted with 70~85% alcohol reflux, recycles ethyl alcohol, and filtrate is condensed into clear cream, obtains
Andrographis Paniculata, filter residue are spare；
S13. the philippine flemingia root for choosing formula ratio is decocted 2 times with water, and each water consumption is 4~10 times of philippine flemingia root weight, when decoction
Between be 2~4 hours, filter collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~1.12, obtain philippine flemingia root
Water extract；
S14. leatherleaf mahonia, the single side needle for choosing formula ratio in proportion, are decocted 2 times with water, and water consumption is the 8 of two taste Chinese medicine total weights
~10 times amount, decocting time be 2~3 hours, collecting decoction, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.08~
1.12, obtain leatherleaf mahonia, single side needle water extract；
S15. cherokee rose root, Caulis Spatholobi, the Radix Codonopsis for choosing formula ratio in proportion, are decocted 2 times with water, add three taste Chinese medicine gross weights for the first time
The water of 4~10 times of amounts of amount, the dregs of a decoction after extracting for the first time add that the resulting Radix Angelicae Sinensis of S11, S12, that the Herba Andrographitis dregs of a decoction decoct 2 together is small
When, amount of water is 4~10 times of amounts of traditional Chinese medicine of the five flavours total weight, and collecting decoction, filtration, filtrate, which merges, to be concentrated, and obtains cherokee rose root, chicken blood
Rattan, Radix Codonopsis water extract；
S16. above-mentioned five kinds of extracts mixed in proportion, be watered dissolution, make the water content 20~35% of extract to get in
Drug composition extract；
S2. the preparation of Traditional Chinese medicinal hand lotion, it is described preparation the following steps are included:
S21. lauryl sodium sulfate, deionized water are proportionally added into, are heated to 60~80 DEG C, stir evenly, until completely mixed
It is molten；
S22. lauroyl propylhomoserin sodium, Cocoamidopropyl betaine are proportionally added into S21 products therefrom, are mixed slowly
Uniformly, stop heating, placement is cooled to 40~50 DEG C, is proportionally added into Chinese medicine composition extract, the potassium sorbate of S1 preparation
It stirs to clarify；
S23. citric acid is dissolved in deionized water, is configured to the citric acid that mass concentration is 20~40%, to be produced obtained by S22
After object is cooling, citric acid is added by formula rate, is stirring evenly and then adding into oil and fat of sacha inchi, sufficiently dissolves it to all substances
Afterwards, essential oil is added dropwise, stirs evenly at a slow speed to get hand cleanser of the present invention.
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| CN113318021A (en) * | 2021-05-26 | 2021-08-31 | 建昌帮药业有限公司 | Hand sanitizer |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113318021A (en) * | 2021-05-26 | 2021-08-31 | 建昌帮药业有限公司 | Hand sanitizer |
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