CN109893589A - A kind of pure plant drug composition for Weight-reducing and lipid-lowering - Google Patents
A kind of pure plant drug composition for Weight-reducing and lipid-lowering Download PDFInfo
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- CN109893589A CN109893589A CN201910306859.8A CN201910306859A CN109893589A CN 109893589 A CN109893589 A CN 109893589A CN 201910306859 A CN201910306859 A CN 201910306859A CN 109893589 A CN109893589 A CN 109893589A
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Abstract
The invention discloses a kind of pure plant drug compositions for Weight-reducing and lipid-lowering, consist of the following components in percentage by weight: aloe extract (aloe-emodin 95%) 1-11%;Green-tea extract (tea polyphenols 98%) 4-14%;Rhizoma Smilacis Glabrae extract (10:1) 9-19%;Radix Adenophorae (Radix Glehniae) extract (10:1) 9-19%;Chinese yam medicament extract (10:1) 12-22%;CAOJUEMING extract (10:1) 6-16%;Senna P.E (10:1) 1-11%;Fruit fermentation ferment (pawpaw, pineapple, apple, pears) 18-28%.Its primary efficacy of the prescription that the present invention is formed is: appetite-suppressing, increases excretion, boosts metabolism, and reduces fat and accumulates in vivo, promotes body fat combustion process.Safety leniently cleans digestive system, facilitates the immune function for maintaining health, provides the infusion of daily critical nutrients.Significant in efficacy to treatment simple obesity, pure natural without side-effects, effect is true, safety, effectively.
Description
Technical field
The present invention relates to health medicine technical field, specially a kind of pure plant medicine for Weight-reducing and lipid-lowering is combined
Object.
Background technique
Western medicine obesity has two classes:
The first kind is the slimming drugs for the maincenter that mainly acts on, such as increasing central nervous system norepinephrine and 5- hydroxyl color
Drug-sibutramine (Sibutramiiie) of amine, it is by inhibiting nervous centralis norepinephrine and serotonin again
It absorbs to reduce appetite, metabolic rate is improved, to achieve the purpose that weight-reducing.Sibutramine can reduce the 5-8% of original body mass, but
The side effect of the medicine is obvious, such as insomnia, dry, constipation, blood pressure and heart rate slightly increase.
Second class is the slimming drugs for mainly acting on periphery, namely reduces the drug of absorption of nutrient ingredients, such as orlistat
(0rlistat trade name Xenical) reduces the absorption of about 1/3 fat of enteron aisle, to reach by inhibiting intestinal fat enzyme
The purpose of weight-reducing.But the side effect of the medicine be incontinence of faces and oil sample just, long-term use may cause liposoluble vitamin to be inhaled
It receives and reduces.
These Western medicine are taken for a long time, there is very big risk.Sibutramine has disabled at present.
Chinese medicine about inhibiting fat and lose weight have long history, the mechanism of traditional Chinese medicine capable of reducing weight be by plant certain
A little ingredients, fat-reducing slimming, relax bowel and defecation, some plant components, which have, to be promoted fat saponification and reduces serum cholesterol and decompression
Effect, traditional Chinese medicine defatting are also approved because of the features such as having no toxic side effect.
Summary of the invention
The purpose of the present invention is to provide a kind of pure plant drug compositions for Weight-reducing and lipid-lowering, to solve above-mentioned back
The problem of being proposed in scape technology, the purpose of the present invention is overcoming Western medicine diet products toxicity height, side effect big, from natural plants
Effective component extracting, it is without side-effects, overcome the adverse reactions such as generated hunger, diarrhea, out of strength, dizzy in weight loss procedures,
Fat extra in vivo is reduced, to achieve the effect that relax bowel and defecation, Weight-reducing and lipid-lowering.
To achieve the above object, the invention provides the following technical scheme: a kind of pure plant medicine for Weight-reducing and lipid-lowering
Composition consists of the following components in percentage by weight:
Aloe extract (aloe-emodin 95%) 1-11%
Green-tea extract (tea polyphenols 98%) 4-14%
Rhizoma Smilacis Glabrae extract (10:1) 9-19%
Radix Adenophorae (Radix Glehniae) extract (10:1) 9-19%
Chinese yam medicament extract (10:1) 12-22%
CAOJUEMING extract (10:1) 6-16%
Senna P.E (10:1) 1-11%
Fruit fermentation ferment (pawpaw, pineapple, apple, pears) 18-28%.
Preferably, the effective component of the aloe extract is aloe-emodin, and wherein the content of aloe-emodin is not
Lower than 95%.
Preferably, the effective component of the green-tea extract is tea polyphenols, and wherein the content of tea polyphenols is not less than 98%.
Preferably, the Rhizoma Smilacis Glabrae extract, Radix Adenophorae (Radix Glehniae) extract, Chinese yam medicament extract, CAOJUEMING extract, folium sennae
Extract is all made of 10 parts of natural plant raw materials and obtains 1 part of extract by extraction.
Preferably, the raw material of fruit fermentation ferment is pawpaw, pineapple, apple, one of pears or a variety of.
Preferably, the dosage form of the pure plant drug composition product for Weight-reducing and lipid-lowering be tablet, wafer,
Granule, lozenge.
Preferably, the pure plant drug composition and pharmaceutically acceptable carrier system for Weight-reducing and lipid-lowering
At the acceptable carrier can be in diluent, lubricant, adhesive, disintegrating agent, sweetener, stabilizer, preservative etc.
One or more kinds of mixtures.
Pure plant Weight-reducing and lipid-lowering health medicine of the present invention, mainly uses aloe extract, green-tea extract, and smilax mentions
Take object, Radix Adenophorae (Radix Glehniae) extract, Chinese yam medicament extract, CAOJUEMING extract, Senna P.E, fruit fermentation ferment (pawpaw, spinach
Trailing plants, apple, pears).It can be made into tablet or capsule, dose is adult 3*300 milligrams daily, early, middle and late daily respectively to take one
Grain (300 milligrams/every).
Compared with prior art, the beneficial effects of the present invention are: prescription its primary efficacy that the present invention is formed is: inhibiting food
It is intended to, increases excretion, boost metabolism, reduce fat and accumulate in vivo, promote body fat combustion process.Safety is leniently
Digestive system is cleaned, facilitates the immune function for maintaining health, the infusion of daily critical nutrients is provided.It is pure natural to make without pair
With effect is true, safety, effectively.
The pharmacological property of drug in inventive formulation is as follows:
Aloe extract has effects that stomach invigorating and laxative, is primarily due to aloe and contains Barbaloin, aloearbonaside, aloe miaow
The effective components such as tincture, have the function of stomach invigorating and laxative, play and improve a poor appetite and large intestine laxative action.Barbaloin is containing anthracene
The derivative of quinone glycocide.Aloe-emodin is released in enteron aisle with digestion promoting function, plays the effect under irritation is rushed down, it is main
Site of action is wanted to have apparent therapeutic effect to a variety of constipation in large intestine.
Effective component tea polyphenols in green-tea extract can be substantially reduced the serum total cholesterol of hyperlipidemia, glycerol three
Rouge, low density lipoprotein cholesterol content, while having the function of recovery and protection function of vascular endothelium.The reducing blood lipid of tea polyphenols
Effect is also one of the main reason for tealeaves can make overweight people's weight-reducing not rebound.
Rhizoma Smilacis Glabrae extract has removing toxic substances, dehumidifying, easing joint movement effect.The root of straight ladybell has the function of adjusting immunologic balance.
Chinese yam medicament extract has reinforcing spleen and kidney, supports the effect of lung, antidiarrheal, arrest sweating.Modern science analysis, Chinese yam rhizome
Maximum feature is containing a large amount of mucin.Mucin is a kind of mixture of proteinpolysaccharide, has special guarantor to human body
Strong effect, can prevent fatty depositing on angiocarpy, keep blood vessel elasticity, and atherosclerosis is prevented to occur to early;It can reduce
Subcutaneous fat deposits;It can prevent the atrophy of connective tissue, the generation of the collagen diseases such as prevention rheumatoid arthritis, chorionitis.Its institute
The dopamine contained has expansion blood vessel, improves sanguimotor critical function, which occupies critical positions in the treatment.
Cassia occidentalis namely cassia seed, extract active constituent are rheum emodin (emodin), Chrysophanol
(chrysophanol), Physcion (physcion), obtusin (obtusin), obtusin (obtusifolin) and
Its glucoside.Cassia seed has the effect of relax bowel and defecation, lipid-loweringing improving eyesight, and clinic is chiefly used in treating constipation and hyperlipidemia, hypertension;
It clears liver and improve vision, sharp water defaecation has laxative action.CAOJUEMING extract effect: decompression, reducing blood lipid, antibacterial, weight-reducing.
Active constituent in Senna P.E is Sennosides, which is converted in colon by microorganism another
Kind substance Rhein anthrone, the effect of the substance advanta are stimulation Colonic Activities, accelerate enterocinesia and improve to digest, increase fluid
Secretion.The laxative effective of Sennosides and its active metabolite Rhein anthrone are considered can inhibit suction of the large intestine to water and electrolyte
It receives, to increase the volume and pressure of intestinal contents.Senna P.E effect: laxative, lipid-loweringing, weight-reducing.
Fruit fermentation ferment (pawpaw, pineapple, apple, pears) has promotion cell metabolism, and gut purge catharsis and toxin expelling subtracts
The effect of fertile lipid-loweringing purifies blood, maintains acid-base property constitution.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
Embodiment 1
A kind of pure plant drug composition for Weight-reducing and lipid-lowering, consists of the following components in percentage by weight:
Aloe extract (aloe-emodin 95%) 1-11%
Green-tea extract (tea polyphenols 98%) 4-14%
Rhizoma Smilacis Glabrae extract (10:1) 9-19%
Radix Adenophorae (Radix Glehniae) extract (10:1) 9-19%
Chinese yam medicament extract (10:1) 12-22%
CAOJUEMING extract (10:1) 6-16%
Senna P.E (10:1) 1-11%
Fruit fermentation ferment (pawpaw, pineapple, apple, pears) 18-28%.
Note: 10:1 i.e. 10 part natural plant raw material obtains 1 part of extract by extraction.
Technique preparation step is as follows:
Above-mentioned powdered extract raw material crosses 80 meshes, extracting screen underflow, trough type mixing machine is then added will through ultraviolet disinfection
Granular material is stirred, and gained mixed powder adds wetting agent (ethyl alcohol), disintegrating agent (starch agent), adhesive (cane sugar powder) to be made
Then softwood is added oscillating granulator for moist powder and required particle is made, adding Fluidbedgranulatingdrier will be wet
The dry whole grain of grain, controls midbody particle moisture 3%.Mixing particle stiffened fatty acid magnesium after gained is dry is made lubricant and (is added
Amount: 0.5%), to increase material fluidity, adding V type high efficient mixer mixed material, then uses rotary tablet machine
By granular material, various shape tablet is made in tabletting, and slice weight determines that at 500 milligrams, control tablet weight variation is passed through ± 10%
Product is obtained after coating.
Embodiment 2
A kind of pure plant drug composition for Weight-reducing and lipid-lowering, consists of the following components in percentage by weight:
Aloe extract (aloe-emodin 95%) 1-11%
Green-tea extract (tea polyphenols 98%) 4-14%
Rhizoma Smilacis Glabrae extract (10:1) 9-19%
Radix Adenophorae (Radix Glehniae) extract (10:1) 9-19%
Chinese yam medicament extract (10:1) 12-22%
CAOJUEMING extract (10:1) 6-16%
Senna P.E (10:1) 1-11%
Fruit fermentation ferment (pawpaw, pineapple, apple, pears) 18-28%.
Note: 10:1 i.e. 10 part natural plant raw material obtains 1 part of extract by extraction.
Technique preparation step is as follows:
By mentioned component drying, ultraviolet disinfection, 80 meshes are crossed, then trough type mixing machine is added by powder in extracting screen underflow
Material is stirred, and auxiliary material magnesium stearate lubricant is added (additional amount: 0.5%), to increase mixing mobility, to be uniformly mixed.Then
Pulverulent mixture material is added in capsule filling machine and makes the capsule that every quality is 300 milligrams, control capsule loading amount is poor
It is different ± 10%.
Embodiment 3
The clinical test of botanical medicine composite preparation of the present invention:
1. diagnostic criteria
Obesity (Obesity) refers to that body fat accumulation excessively and to the physical condition that health adversely affects, may be led
Cause reduced lifetime and various health problems.Fat standard is often used body-mass index (BMI) Lai Hengliang, i.e., (public with weight
Jin) divided by square of height (meter), it is normal in the world
Measure the fat or thin degree of human body and whether Jian Kang a standard.When the weight pair for needing to compare and analyze a people
When the health effect brought by the people of different height, BMI value is a neutrality and reliable index.Westerner thinks BMI
Greater than 30kg/m2It is as fat, 30kg/m is arrived between 252Between then to be overweight.China uses more stringent standard, normal model
Enclosing is 18.5-23.9, and 24-27.9 just belongs to overweight, and 28 or more be exactly fat.For children, BMI diagnostic criteria
It has any different with adult, slightly lower.
2. criterion of therapeutical effect
Effective: weight loss 3KG or more or abdominal circumference reduce 6cm or more.
Effective: weight loss 1.5KG-3KG or abdominal circumference reduce 3cm-6cm.
Invalid: weight loss reduces less than 1.5KG or abdominal circumference less than 3cm.
3. treatment method
It is obesity patient 120 that inventor collects after diagnosing, wherein male 50, female 70;Age 18-65 years old, disease
Journey 1-10.
Instructions of taking: the oral capsule preparation as obtained by above-described embodiment 2.3 capsules are taken daily, daily
It is early, middle and late respectively to take a capsule, with warm water swallowable capsule, 30 days courses for the treatment of.
4. treatment results
Table 1: Grenzen der Adipositasbehandlung clinical trials condition
Treatment results:
Medicine composite for curing obesity disease 120 of the present invention known to table 1, effective 94, effective 23, in vain
3, obvious effective rate 78%, effective percentage is 19%, total effective rate 97%.
Clinical case:
1. patient A, male, 25 years old, height 168cm, 85 kilograms of (BMI:30.1kg/m of weight2)。
Symptoms: body fat accumulates in abdomen, buttocks, and lower limb are fat, and shortness of breath skelagia when movable often has feeling of fatigue,
Honey stomach, sweet tooth etc..By taking the pure plant drug composition of Weight-reducing and lipid-lowering, after 3 months, weight is kept to 60
Kilogram, other symptoms disappear.
2. patient B, male, 46 years old, height 178cm, 120 kilograms of (BMI:37.9kg/m of weight2).It does not advise for a long time
The work and rest of rule, diet heat is higher, is on the drink, and is negligent of moving, and very big problem also occurs in health.Symptoms:
Nervous dizzy, normal cold perspiration, tired powerless, appetite increases, weight abruptly increase, takes action restricted.By the pure day for taking Weight-reducing and lipid-lowering
Right plant drug composition, weight reduces to 78 kilograms after 3 months.
3. patient C, male, 55 years old, height 171cm, 78 kilograms of (BMI:26.7kg/m of weight2).In operating pressure
Weight abruptly increase before 2 years, drinks beyond one's capacity often in the case where big, the thermophilic meat or fish of diet and detest element, gradually form abdominal distension, it is tired heavy.
By taking the pure plant drug composition of Weight-reducing and lipid-lowering, after 3 months, weight is kept to 68 kilograms.
4. patient D, female, 27 years old, height 168cm, 86 kilograms of (BMI:30.5kg/m of weight2), medication 3
Weight reduces to 74 kilograms after a month, reduces 12 kilograms, and abdomen and waist upper-arm circumference are obviously shown in thin, and readme duration of medication need not section
Food, has no adverse reaction.
5. patient E, female, 33 years old, height 160cm, 72 kilograms of (BMI:28.1kg/m of weight2).Postpartum, fertile fat
It is constantly deposited in abdomen, body gradually increases fat, restricted, spiritlessness and weakness of taking action.By the pure plant medicine for taking Weight-reducing and lipid-lowering
Composition, after 3 months, weight is kept to 56 kilograms, and with a slim and graceful figure, freely, livelihood restoration is normal for activity.
Clinical observation is summarized: the invention medicine composite for curing simple obesity 120, is controlled within severe 1-3 months
More, weight, body fat content and waistline, hip circumference are reduced, total effective rate 97%.The plant drug composition can improve people
Body metabolism, effectively cleaning stomach, reach Weight-reducing and lipid-lowering curative effect.Internal superabundant fats can be dissolved after medication, adjust Digestive
System.Blood routine and blood biochemical measurement result and blood pressure are in normal range (NR), spirit, sleep, diet shape before and after subject
Condition is good.Do not find that the drug has apparent adverse reaction during medication.Experiments have shown that invention treatment simple obesity is treated
Effect is significant, has no toxic side effect, and pharmaceutical composition of the present invention uses safe and effective.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (7)
1. a kind of pure plant drug composition for Weight-reducing and lipid-lowering, which is characterized in that by following components in percentage by weight
Composition:
Aloe extract (aloe-emodin 95%) 1-11%
Green-tea extract (tea polyphenols 98%) 4-14%
Rhizoma Smilacis Glabrae extract (10:1) 9-19%
Radix Adenophorae (Radix Glehniae) extract (10:1) 9-19%
Chinese yam medicament extract (10:1) 12-22%
CAOJUEMING extract (10:1) 6-16%
Senna P.E (10:1) 1-11%
Fruit fermentation ferment (pawpaw, pineapple, apple, pears) 18-28%.
2. a kind of pure plant drug composition for Weight-reducing and lipid-lowering according to claim 1, which is characterized in that described
Aloe extract effective component be aloe-emodin, wherein the content of aloe-emodin be not less than 95%.
3. a kind of pure plant drug composition for Weight-reducing and lipid-lowering according to claim 1, which is characterized in that described
Green-tea extract effective component be tea polyphenols, wherein the content of tea polyphenols be not less than 98%.
4. a kind of pure plant drug composition for Weight-reducing and lipid-lowering according to claim 1, which is characterized in that described
Rhizoma Smilacis Glabrae extract, Radix Adenophorae (Radix Glehniae) extract, Chinese yam medicament extract, CAOJUEMING extract, rush down leaf extract be all made of 10 parts it is natural
Plant material obtains 1 part of extract by extraction.
5. a kind of pure plant drug composition for Weight-reducing and lipid-lowering according to claim 1, which is characterized in that described
Fruit fermentation ferment be pawpaw, pineapple, apple, one of pears or a variety of.
6. a kind of pure plant drug composition for Weight-reducing and lipid-lowering according to claim 1, which is characterized in that described
The dosage form of the pure plant drug composition product for Weight-reducing and lipid-lowering be tablet, wafer, granule, lozenge.
7. a kind of pure plant drug composition for Weight-reducing and lipid-lowering according to claim 1, which is characterized in that described
The pure plant drug composition for Weight-reducing and lipid-lowering be made with pharmaceutically acceptable carrier, the acceptable carrier can
To be one of diluent, lubricant, adhesive, disintegrating agent, sweetener, stabilizer, preservative etc. or more than one is mixed
Close object.
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