CN101444614B - Pharmaceutical composition with fat burning and firming effect and preparation method thereof - Google Patents

Pharmaceutical composition with fat burning and firming effect and preparation method thereof Download PDF

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Publication number
CN101444614B
CN101444614B CN2008102470186A CN200810247018A CN101444614B CN 101444614 B CN101444614 B CN 101444614B CN 2008102470186 A CN2008102470186 A CN 2008102470186A CN 200810247018 A CN200810247018 A CN 200810247018A CN 101444614 B CN101444614 B CN 101444614B
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weight portion
pharmaceutical composition
weight
crude drug
vitamin
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CN2008102470186A
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CN101444614A (en
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宫守汪
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Abstract

The invention discloses a pharmaceutical composition with fat burning and firming effect and a preparation method thereof. The bulk drugs comprise Chinese yam, China root greenbrier rhizome, curcuma, cattail pollen, lotus leaf, pseudo-ginseng, pangolin and vitamin B. The pharmaceutical composition can be prepared into does types which can be accepted clinically by adding pharmaceutically conventional auxiliary materials according to the conventional process. The pharmaceutical composition has the biologic far infrared function, and has the effects of burning and dissolving adipocytokine, adipocytokine saggy skin, mitigating the ageing of skin, removing eye pouch, and removing wrinkles, can enable human body to enhance the cellular metabolism, and can cause the skin to enhance the capability for resisting exogenous factor. The pharmaceutical composition has obvious treatment effects on adiposis, eye punch sagging, acanthosis nigricans and other diseases.

Description

Has pharmaceutical composition of fat burning and firming effect and preparation method thereof
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition and preparation method thereof with fat burning and firming effect.
Background technology
Obesity is a kind of modern civilization disease, because the raising of people's living standard and unreasonable and some other factor of nutrition, obese people presents the trend that rises year by year in worldwide.At present, there are 1,200,000,000 obesity patients in the world, and the obesity sickness rate of American-European developed country is up to more than 40%, and China's incidence of obesity is also increasing rapidly, and some areas reach more than 30%.Obesity not only influences attractive in appearancely, is more classified as one of three human big diseases because of its dangers to health by current medical circle.How to cure obesity, become a global difficult problem together.
Obesity is the disease that is caused by the h and E reciprocal action, is due to the fatty tissue excessive savings in vivo.The lipogenesis increase is the material base of causeing fat.Common method of weight-reducing has weight-reducing by dieting method, weight reduction with drugs method.The weight-reducing by dieting rule as, with the low heat value food meal, or Semi-Starvation, the general description and quantity that all limits feed owing to limited feed, does not guarantee eutrophic needs, can make the people weak, anorexia, health is affected.Pharmacotherapy generally is to have certain effect at first, and is not lasting, also can accompany by the restriction feed, though said method has fat-reducing effect, but not lasting, can rebound fat-reducing again, bounce-back again after the fat-reducing again.Also have a kind of diarrhoea method, by diarrhoea the people is lost weight, go to bits, World Health Organization (WHO) proposes the fat-reducing principle and should be not weak, not anorexia, three conditions of not suffering from diarrhoea, and above-mentioned method of weight-reducing does not all reach this condition.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition with fat burning and firming effect, another object of the present invention is to provide this preparation of drug combination method.
The present invention is achieved through the following technical solutions:
The crude drug of pharmaceutical composition of the present invention consists of:
Rhizoma Dioscoreae 10-30 weight portion Poria 10-40 weight portion Rhizoma Curcumae Longae 5-25 weight portion
Pollen Typhae 10-30 weight portion Folium Nelumbinis 5-25 weight portion Radix Notoginseng 10-40 weight portion
Squama Manis 15-55 weight portion vitamin B 2.5-7.5 weight portion.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Rhizoma Dioscoreae 20 weight portion Porias 25 weight portion Rhizoma Curcumae Longaes 15 weight portions
Pollen Typhae 20 weight portion Folium Nelumbinis 15 weight portion Radix Notoginsengs 25 weight portions
Squama Manis 35 weight portion vitamin Bs 5 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Rhizoma Dioscoreae 28 weight portion Porias 15 weight portion Rhizoma Curcumae Longaes 22 weight portions
Pollen Typhae 12 weight portion Folium Nelumbinis 22 weight portion Radix Notoginsengs 15 weight portions
Squama Manis 50 weight portion vitamin Bs 3 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Rhizoma Dioscoreae 12 weight portion Porias 35 weight portion Rhizoma Curcumae Longaes 9 weight portions
Pollen Typhae 28 weight portion Folium Nelumbinis 9 weight portion Radix Notoginsengs 35 weight portions
Squama Manis 20 weight portion vitamin Bs 7 weight portions.
Preparation of drug combination method of the present invention is:
With the crude drug drying and sterilizing, beat powder to 1000 order, add the 50-70 degree Chinese liquor dilution of crude drug powder 2-4 times of weight, promptly get pharmaceutical composition of the present invention.
Preparation of drug combination method of the present invention is preferably:
With the crude drug drying and sterilizing, beat powder to 1000 order, add 60 degree Chinese liquor dilutions of crude drug powder 3 times of weight, promptly get pharmaceutical composition of the present invention.
Pharmaceutical composition of the present invention is made clinical acceptable forms according to the conventional adjuvant that common process adds pharmaceutically, as medicated wine, powder, emplastrum, ointment, ointment, pill, tablet, capsule or granule etc.
Pharmaceutical composition of the present invention has biological far-infrared functional, and the burning dissolved fat factor is shunk sagging skin, alleviates skin aging, and the effect of the eye pouch of dispelling, wrinkle removal stricture of vagina can make the human body cell metabolism strengthen, and makes skin strengthen the ability of resisting exopathogen.For treatment obesity, eye leukorrhagia hang down, sick effect such as black sour jujube skin is remarkable.
Following experimental example and embodiment are used to further specify but are not limited to the present invention:
Medicine composite for curing obesity 100 routine clinical observations of the present invention
One, physical data
100 routine patients all are the outpatient, wherein male 25 examples, and women 75 examples, the oldest 54 years old, minimum 15 years old, the course of disease had 3 examples in the longest 11 years, 43 examples was arranged in the shortest 2 years, and the vertical disease of eye leukorrhagia has 36 examples, and acanthosis nigricans disease has 9 examples etc.; Produce effects 82 examples wherein, effective 18 examples, invalid 0 example.
Two, diagnostic criteria
The tcm diagnosis standard: because of function disorder Metabolic disorder causes rubbish to pile up in vivo, Excessive Intake consumes and to cause heat too much to store in vivo very little to form fat, and what exceeded body weight is called obesity more than 20%.
Three, criterion of therapeutical effect
Produce effects: lose weight more than the 3kg, abdominal circumference reduces more than the 6cm, and skin wrinkle and relaxed state obviously improve, and it is normal that skin recovers.
Effectively: lose weight 1.5kg-3kg or abdominal circumference reduce 3cm-6cm, and skin wrinkle and relaxed state improve, and it is normal that skin recovers substantially.
Invalid: the not enough 1.5kg that loses weight, skin wrinkle and relaxed state do not have improvement.
Four, Therapeutic Method
Medicine is formed: Rhizoma Dioscoreae 20g, Poria 25g, Rhizoma Curcumae Longae 15g, Pollen Typhae 20g, Folium Nelumbinis 15g, Radix Notoginseng 25g, Squama Manis 35g, vitamin B 5g.
Preparation method: with the crude drug drying and sterilizing, beat powder to 1000 order, add 60 degree Chinese liquor dilutions of crude drug powder 3 times of weight, promptly.
Using method: be coated with fat place outward, once a day, each 5-15 gram is coated the back massage.
Five, therapeutic outcome
To sum up, medicine composite for curing obesity 100 examples of the present invention, produce effects 82 examples, effective 15 examples, invalid 3 examples.Obvious effective rate is 82%, and effective percentage is 18%, total effective rate 100%.
Six, model case
Case 1: Zhai *, the woman, 23 years old, obesity, two eye pouch sagging (athero), two upper arm skin are slightly black, 186.5 jin of its body weight, 1.65 meters waistline 3.1 chis of height, through use the embodiment of the invention 1 medicine after three months skin change normal, the convergence of eye band, waistline is received to 2.3 chis, does not have bounce-back over 2 years, and end-body heavily is 130 jin.
Case 2: meter * *, woman, 43 years old, 167.5 jin of body weight, waist and lower abdomen skin pine are rushed down sagging, and two eye pouch are sagging, upper arm and thigh skin are slightly black, 167.5 jin of its body weight, 1.61 meters of heights, medicine through using the embodiment of the invention 2 after three months skin gloss flexible, dark skin changes normal, and the convergence of eye band is normal, and the lower abdomen dermostenosis is no longer sagging, body weight reduces to 120 jin, nothing bounce-back in 2 years four months so far.
Following embodiment all can realize the effect of above-mentioned experimental example:
The specific embodiment
Embodiment 1:
Rhizoma Dioscoreae 20kg Poria 25kg Rhizoma Curcumae Longae 15kg
Pollen Typhae 20kg Folium Nelumbinis 15kg Radix Notoginseng 25kg
Squama Manis 35kg vitamin B 5kg;
With the said medicine drying and sterilizing, beat powder to 1000 order, add 60 degree Chinese liquor dilutions of crude drug powder 3 times of weight, promptly get medicated wine.Once a day, each 5-15 gram is coated with fat place outward, coats the back massage.
Embodiment 2:
Rhizoma Dioscoreae 28kg Poria 15kg Rhizoma Curcumae Longae 22kg
Pollen Typhae 12kg Folium Nelumbinis 22kg Radix Notoginseng 15kg
Squama Manis 50kg vitamin B 3kg;
Get the above-mentioned raw materials medicine, make powder according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 3:
Rhizoma Dioscoreae 12kg Poria 35kg Rhizoma Curcumae Longae 9kg
Pollen Typhae 28kg Folium Nelumbinis 9kg Radix Notoginseng 35kg
Squama Manis 20kg vitamin B 7kg;
Get the above-mentioned raw materials medicine, make emplastrum according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 4:
Rhizoma Dioscoreae 20kg Poria 25kg Rhizoma Curcumae Longae 15kg
Pollen Typhae 20kg Folium Nelumbinis 15kg Radix Notoginseng 25kg
Squama Manis 35kg vitamin B 5kg;
Get the above-mentioned raw materials medicine, make capsule according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 5:
Rhizoma Dioscoreae 28kg Poria 15kg Rhizoma Curcumae Longae 22kg
Pollen Typhae 12kg Folium Nelumbinis 22kg Radix Notoginseng 15kg
Squama Manis 50kg vitamin B 3kg;
Get the above-mentioned raw materials medicine, make granule according to the conventional adjuvant that common process adds pharmaceutically.

Claims (9)

1. pharmaceutical composition with fat burning and firming effect is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Dioscoreae 10-30 weight portion Poria 10-40 weight portion Rhizoma Curcumae Longae 5-25 weight portion
Pollen Typhae 10-30 weight portion Folium Nelumbinis 5-25 weight portion Radix Notoginseng 10-40 weight portion
Squama Manis 15-55 weight portion vitamin B 2.5-7.5 weight portion.
2. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Dioscoreae 20 weight portion Porias 25 weight portion Rhizoma Curcumae Longaes 15 weight portions
Pollen Typhae 20 weight portion Folium Nelumbinis 15 weight portion Radix Notoginsengs 25 weight portions
Squama Manis 35 weight portion vitamin Bs 5 weight portions.
3. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Dioscoreae 28 weight portion Porias 15 weight portion Rhizoma Curcumae Longaes 22 weight portions
Pollen Typhae 12 weight portion Folium Nelumbinis 22 weight portion Radix Notoginsengs 15 weight portions
Squama Manis 50 weight portion vitamin Bs 3 weight portions.
4. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Dioscoreae 12 weight portion Porias 35 weight portion Rhizoma Curcumae Longaes 9 weight portions
Pollen Typhae 28 weight portion Folium Nelumbinis 9 weight portion Radix Notoginsengs 35 weight portions
Squama Manis 20 weight portion vitamin Bs 7 weight portions.
5. as claim 1,2,3 or 4 arbitrary described pharmaceutical compositions, it is characterized in that this pharmaceutical composition makes the dosage form of clinical acceptance according to the conventional adjuvant that common process adds pharmaceutically.
6. pharmaceutical composition as claimed in claim 5 is characterized in that described dosage form is: medicated wine, powder, emplastrum, ointment, ointment, pill, tablet, capsule or granule.
7. as claim 1,2,3 or 4 arbitrary described preparation of drug combination methods, it is characterized in that this method is: with the crude drug drying and sterilizing, beat powder to 1000 order, add the 50-70 degree Chinese liquor dilution of crude drug powder 2-4 times of weight, promptly get pharmaceutical composition of the present invention.
8. preparation of drug combination method as claimed in claim 7 is characterized in that this method is: with the crude drug drying and sterilizing, beat powder to 1000 order, add 60 degree Chinese liquor dilutions of crude drug powder 3 times of weight, promptly get pharmaceutical composition of the present invention.
As claim 1,2,3 or 4 arbitrary described pharmaceutical compositions preparation treatment obesity, eye leukorrhagia hang down or the medicine of black sour jujube skin in application.
CN2008102470186A 2008-12-31 2008-12-31 Pharmaceutical composition with fat burning and firming effect and preparation method thereof Expired - Fee Related CN101444614B (en)

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Application Number Priority Date Filing Date Title
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106474017A (en) * 2016-12-20 2017-03-08 韦罡 A kind of spring flower condensed cream and its application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1101842A (en) * 1993-10-20 1995-04-26 裴坤苓 Health oral liquid for weight loss
CN1424102A (en) * 2002-12-27 2003-06-18 王�琦 Chinese medicine preparation for weight-off and reducing fat
CN1738633A (en) * 2002-12-27 2006-02-22 韩国韩医学研究院 Anti-obesity ingretients from medicinal plants and their composittion

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1101842A (en) * 1993-10-20 1995-04-26 裴坤苓 Health oral liquid for weight loss
CN1424102A (en) * 2002-12-27 2003-06-18 王�琦 Chinese medicine preparation for weight-off and reducing fat
CN1738633A (en) * 2002-12-27 2006-02-22 韩国韩医学研究院 Anti-obesity ingretients from medicinal plants and their composittion

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