CN109890207B - 包含可逆修饰的寡核苷酸的组合物及其用途 - Google Patents
包含可逆修饰的寡核苷酸的组合物及其用途 Download PDFInfo
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210479298.3A CN114891053A (zh) | 2016-08-23 | 2017-08-23 | 包含可逆修饰的寡核苷酸的组合物及其用途 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662378635P | 2016-08-23 | 2016-08-23 | |
| US62/378635 | 2016-08-23 | ||
| PCT/US2017/048239 WO2018039364A1 (en) | 2016-08-23 | 2017-08-23 | Compositions comprising reversibly modified oligonucleotides and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210479298.3A Division CN114891053A (zh) | 2016-08-23 | 2017-08-23 | 包含可逆修饰的寡核苷酸的组合物及其用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109890207A CN109890207A (zh) | 2019-06-14 |
| CN109890207B true CN109890207B (zh) | 2022-05-27 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780065632.8A Active CN109890207B (zh) | 2016-08-23 | 2017-08-23 | 包含可逆修饰的寡核苷酸的组合物及其用途 |
| CN202210479298.3A Withdrawn CN114891053A (zh) | 2016-08-23 | 2017-08-23 | 包含可逆修饰的寡核苷酸的组合物及其用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210479298.3A Withdrawn CN114891053A (zh) | 2016-08-23 | 2017-08-23 | 包含可逆修饰的寡核苷酸的组合物及其用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11390642B2 (https=) |
| EP (1) | EP3503730B1 (https=) |
| JP (2) | JP7249080B2 (https=) |
| KR (1) | KR102530513B1 (https=) |
| CN (2) | CN109890207B (https=) |
| AU (2) | AU2017315670B2 (https=) |
| CA (1) | CA3032165C (https=) |
| IL (2) | IL264685B (https=) |
| MX (2) | MX2019002075A (https=) |
| WO (1) | WO2018039364A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102350647B1 (ko) * | 2016-09-02 | 2022-01-14 | 다이서나 파마수이티컬, 인크. | 4'-포스페이트 유사체 및 이를 포함하는 올리고뉴클레오타이드 |
| EP3697423A4 (en) | 2018-01-05 | 2021-08-11 | Dicerna Pharmaceuticals, Inc. | REDUCED EXPRESSION OF BETA-CATENIN AND IDO TO POTENTIALIZE IMMUNOTHERAPY |
| WO2019143621A1 (en) | 2018-01-16 | 2019-07-25 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for inhibiting aldh2 expression |
| CA3135402A1 (en) | 2019-04-04 | 2020-10-08 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for inhibiting gene expression in the central nervous system |
| EP4116422A4 (en) * | 2020-03-03 | 2024-03-20 | Nexmos Co., Ltd. | Dna aptamer specifically binding to glutathione and use thereof |
| IL300283A (en) | 2020-08-04 | 2023-04-01 | Dicerna Pharmaceuticals Inc | Systemic administration of oligonucleotides |
| IL301940A (en) | 2020-10-08 | 2023-06-01 | Dicerna Pharmaceuticals Inc | Selective delivery of oligonucleotides to glial cells |
| EP4271695A2 (en) * | 2020-12-31 | 2023-11-08 | Alnylam Pharmaceuticals, Inc. | 2'-modified nucleoside based oligonucleotide prodrugs |
| US12084662B2 (en) | 2021-04-14 | 2024-09-10 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for modulating PNPLA3 expression |
| AU2022324471A1 (en) | 2021-08-05 | 2024-02-15 | Sanegene Bio Usa Inc. | 1'-alkyl modified ribose derivatives and methods of use |
| EP4405368A1 (en) | 2021-09-22 | 2024-07-31 | Sanegene Bio USA Inc. | 2'-alkyl or 3'- alkyl modified ribose derivatives for use in the in-vivo delivery of oligonucleotides |
| WO2023047338A1 (en) * | 2021-09-24 | 2023-03-30 | Crispr Therapeutics Ag | PRODRUG INCORPORATED sgRNA SYNTHESIS |
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| US11390642B2 (en) | 2022-07-19 |
| KR20190040033A (ko) | 2019-04-16 |
| US20230101227A1 (en) | 2023-03-30 |
| CA3032165A1 (en) | 2018-03-01 |
| IL295212A (en) | 2022-10-01 |
| AU2017315670A1 (en) | 2019-02-14 |
| JP2019526555A (ja) | 2019-09-19 |
| AU2017315670B2 (en) | 2022-03-17 |
| EP3503730C0 (en) | 2023-09-27 |
| US12037358B2 (en) | 2024-07-16 |
| NZ750307A (en) | 2021-11-26 |
| MX2019002075A (es) | 2019-07-01 |
| AU2022204225A1 (en) | 2022-07-07 |
| EP3503730A1 (en) | 2019-07-03 |
| IL264685B (en) | 2022-09-01 |
| KR102530513B1 (ko) | 2023-05-08 |
| US20190177355A1 (en) | 2019-06-13 |
| JP7249080B2 (ja) | 2023-03-30 |
| CN109890207A (zh) | 2019-06-14 |
| IL264685A (https=) | 2019-03-31 |
| MX2021014769A (es) | 2022-01-18 |
| CN114891053A (zh) | 2022-08-12 |
| EP3503730A4 (en) | 2020-09-23 |
| WO2018039364A1 (en) | 2018-03-01 |
| EP3503730B1 (en) | 2023-09-27 |
| CA3032165C (en) | 2023-05-16 |
| JP2022106928A (ja) | 2022-07-20 |
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