KR102530513B1 - 가역적으로 변형된 올리고뉴클레오티드를 포함하는 조성물 및 그의 용도 - Google Patents
가역적으로 변형된 올리고뉴클레오티드를 포함하는 조성물 및 그의 용도 Download PDFInfo
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- KR102530513B1 KR102530513B1 KR1020197007856A KR20197007856A KR102530513B1 KR 102530513 B1 KR102530513 B1 KR 102530513B1 KR 1020197007856 A KR1020197007856 A KR 1020197007856A KR 20197007856 A KR20197007856 A KR 20197007856A KR 102530513 B1 KR102530513 B1 KR 102530513B1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662378635P | 2016-08-23 | 2016-08-23 | |
| US62/378,635 | 2016-08-23 | ||
| PCT/US2017/048239 WO2018039364A1 (en) | 2016-08-23 | 2017-08-23 | Compositions comprising reversibly modified oligonucleotides and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190040033A KR20190040033A (ko) | 2019-04-16 |
| KR102530513B1 true KR102530513B1 (ko) | 2023-05-08 |
Family
ID=61245366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197007856A Active KR102530513B1 (ko) | 2016-08-23 | 2017-08-23 | 가역적으로 변형된 올리고뉴클레오티드를 포함하는 조성물 및 그의 용도 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11390642B2 (https=) |
| EP (1) | EP3503730B1 (https=) |
| JP (2) | JP7249080B2 (https=) |
| KR (1) | KR102530513B1 (https=) |
| CN (2) | CN109890207B (https=) |
| AU (2) | AU2017315670B2 (https=) |
| CA (1) | CA3032165C (https=) |
| IL (2) | IL264685B (https=) |
| MX (2) | MX2019002075A (https=) |
| WO (1) | WO2018039364A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE059718T2 (hu) * | 2016-09-02 | 2022-12-28 | Dicerna Pharmaceuticals Inc | 4'-foszfát analógok és azokat tartalmazó oligonukleotidok |
| US11813280B2 (en) | 2018-01-05 | 2023-11-14 | Dicerna Pharmaceuticals, Inc. | Reducing beta-catenin and IDO expression to potentiate immunotherapy |
| KR20200109311A (ko) | 2018-01-16 | 2020-09-22 | 다이서나 파마수이티컬, 인크. | Aldh2 발현을 억제하기 위한 조성물 및 방법 |
| BR112021019793A2 (pt) | 2019-04-04 | 2021-12-07 | Dicerna Pharmaceuticals Inc | Composições e métodos para inibir expressão de gene no sistema nervoso central |
| WO2021177657A1 (ko) * | 2020-03-03 | 2021-09-10 | 주식회사 넥스모스 | 글루타치온에 특이적으로 결합하는 dna 압타머 및 그의 용도 |
| KR20230061389A (ko) | 2020-08-04 | 2023-05-08 | 다이서나 파마수이티컬, 인크. | 올리고뉴클레오티드의 전신 전달 |
| EP4225919A1 (en) | 2020-10-08 | 2023-08-16 | Dicerna Pharmaceuticals, Inc. | Selective delivery of oligonucleotides to glial cells |
| EP4271695A2 (en) * | 2020-12-31 | 2023-11-08 | Alnylam Pharmaceuticals, Inc. | 2'-modified nucleoside based oligonucleotide prodrugs |
| CA3209418A1 (en) | 2021-04-14 | 2022-10-20 | Utsav SAXENA | Compositions and methods for modulating pnpla3 expression |
| US12465647B2 (en) | 2021-08-05 | 2025-11-11 | Sanegene Bio Usa Inc. | 1′-alkyl modified ribose derivatives and methods of use |
| EP4405368A1 (en) | 2021-09-22 | 2024-07-31 | Sanegene Bio USA Inc. | 2'-alkyl or 3'- alkyl modified ribose derivatives for use in the in-vivo delivery of oligonucleotides |
| US20230105319A1 (en) * | 2021-09-24 | 2023-04-06 | Crispr Therapeutics Ag | PRODRUG INCORPORATED sgRNA SYNTHESIS |
| EP4413015A1 (en) | 2021-10-05 | 2024-08-14 | Sanegene Bio USA Inc. | Polyhydroxylated cyclopentane derivatives and methods of use |
| JP2024543195A (ja) | 2021-12-01 | 2024-11-19 | ディセルナ ファーマシューティカルズ インコーポレイテッド | Apoc3発現を調節するための組成物及び方法 |
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| WO2015032968A1 (en) | 2013-09-09 | 2015-03-12 | University Of Vienna | Antisense oligonucleotides with improved pharmacokinetic properties |
| WO2015069932A1 (en) | 2013-11-06 | 2015-05-14 | Solstice Biologics, Ltd. | Polynucleotide constructs having disulfide groups |
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| JP7249080B2 (ja) | 2023-03-30 |
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| EP3503730C0 (en) | 2023-09-27 |
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| MX2021014769A (es) | 2022-01-18 |
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| AU2017315670B2 (en) | 2022-03-17 |
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| AU2017315670A1 (en) | 2019-02-14 |
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