KR102530513B1 - 가역적으로 변형된 올리고뉴클레오티드를 포함하는 조성물 및 그의 용도 - Google Patents

가역적으로 변형된 올리고뉴클레오티드를 포함하는 조성물 및 그의 용도 Download PDF

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KR102530513B1
KR102530513B1 KR1020197007856A KR20197007856A KR102530513B1 KR 102530513 B1 KR102530513 B1 KR 102530513B1 KR 1020197007856 A KR1020197007856 A KR 1020197007856A KR 20197007856 A KR20197007856 A KR 20197007856A KR 102530513 B1 KR102530513 B1 KR 102530513B1
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glutathione
delete delete
sensitive
oligonucleotide
substituted
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KR20190040033A (ko
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웨이민 왕
벤카타 크리쉬나무르티
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다이서나 파마수이티컬, 인크.
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KR1020197007856A 2016-08-23 2017-08-23 가역적으로 변형된 올리고뉴클레오티드를 포함하는 조성물 및 그의 용도 Active KR102530513B1 (ko)

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US201662378635P 2016-08-23 2016-08-23
US62/378,635 2016-08-23
PCT/US2017/048239 WO2018039364A1 (en) 2016-08-23 2017-08-23 Compositions comprising reversibly modified oligonucleotides and uses thereof

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KR20190040033A KR20190040033A (ko) 2019-04-16
KR102530513B1 true KR102530513B1 (ko) 2023-05-08

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US (2) US11390642B2 (https=)
EP (1) EP3503730B1 (https=)
JP (2) JP7249080B2 (https=)
KR (1) KR102530513B1 (https=)
CN (2) CN109890207B (https=)
AU (2) AU2017315670B2 (https=)
CA (1) CA3032165C (https=)
IL (2) IL264685B (https=)
MX (2) MX2019002075A (https=)
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KR102350647B1 (ko) * 2016-09-02 2022-01-14 다이서나 파마수이티컬, 인크. 4'-포스페이트 유사체 및 이를 포함하는 올리고뉴클레오타이드
EP3697423A4 (en) 2018-01-05 2021-08-11 Dicerna Pharmaceuticals, Inc. REDUCED EXPRESSION OF BETA-CATENIN AND IDO TO POTENTIALIZE IMMUNOTHERAPY
WO2019143621A1 (en) 2018-01-16 2019-07-25 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting aldh2 expression
CA3135402A1 (en) 2019-04-04 2020-10-08 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting gene expression in the central nervous system
EP4116422A4 (en) * 2020-03-03 2024-03-20 Nexmos Co., Ltd. Dna aptamer specifically binding to glutathione and use thereof
IL300283A (en) 2020-08-04 2023-04-01 Dicerna Pharmaceuticals Inc Systemic administration of oligonucleotides
IL301940A (en) 2020-10-08 2023-06-01 Dicerna Pharmaceuticals Inc Selective delivery of oligonucleotides to glial cells
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