JP7249080B2 - 可逆的に修飾されたオリゴヌクレオチドを含む組成物及びその使用 - Google Patents

可逆的に修飾されたオリゴヌクレオチドを含む組成物及びその使用 Download PDF

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JP7249080B2
JP7249080B2 JP2019508973A JP2019508973A JP7249080B2 JP 7249080 B2 JP7249080 B2 JP 7249080B2 JP 2019508973 A JP2019508973 A JP 2019508973A JP 2019508973 A JP2019508973 A JP 2019508973A JP 7249080 B2 JP7249080 B2 JP 7249080B2
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glutathione
formula
substituted
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oligonucleotide
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JP2019526555A (ja
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ウェイミン ワン
ベンカタ クリシュナマーシー
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Dicerna Pharmaceuticals Inc
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JP2019508973A 2016-08-23 2017-08-23 可逆的に修飾されたオリゴヌクレオチドを含む組成物及びその使用 Active JP7249080B2 (ja)

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PCT/US2017/048239 WO2018039364A1 (en) 2016-08-23 2017-08-23 Compositions comprising reversibly modified oligonucleotides and uses thereof

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CN (2) CN109890207B (https=)
AU (2) AU2017315670B2 (https=)
CA (1) CA3032165C (https=)
IL (2) IL264685B (https=)
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KR102350647B1 (ko) * 2016-09-02 2022-01-14 다이서나 파마수이티컬, 인크. 4'-포스페이트 유사체 및 이를 포함하는 올리고뉴클레오타이드
EP3697423A4 (en) 2018-01-05 2021-08-11 Dicerna Pharmaceuticals, Inc. REDUCED EXPRESSION OF BETA-CATENIN AND IDO TO POTENTIALIZE IMMUNOTHERAPY
WO2019143621A1 (en) 2018-01-16 2019-07-25 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting aldh2 expression
CA3135402A1 (en) 2019-04-04 2020-10-08 Dicerna Pharmaceuticals, Inc. Compositions and methods for inhibiting gene expression in the central nervous system
EP4116422A4 (en) * 2020-03-03 2024-03-20 Nexmos Co., Ltd. Dna aptamer specifically binding to glutathione and use thereof
IL300283A (en) 2020-08-04 2023-04-01 Dicerna Pharmaceuticals Inc Systemic administration of oligonucleotides
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