CN109876042A - A kind of Chinese traditional medicine composition and preparation method thereof for treating verruca plana - Google Patents

A kind of Chinese traditional medicine composition and preparation method thereof for treating verruca plana Download PDF

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CN109876042A
CN109876042A CN201910331903.0A CN201910331903A CN109876042A CN 109876042 A CN109876042 A CN 109876042A CN 201910331903 A CN201910331903 A CN 201910331903A CN 109876042 A CN109876042 A CN 109876042A
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powder
parts
tincture
coptis
medicine composition
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李卫平
李书红
米明
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Abstract

The invention discloses a kind of Chinese traditional medicine composition and preparation method thereof for treating verruca plana, the Chinese traditional medicine composition includes tincture and powder, and the formula of the tincture is as follows by weight: 25-35 parts of psoralea corylifolia, 3-10 parts of the coptis, 50-70 parts of 75% ethyl alcohol;The powder is 15-20 parts of borax of finely ground 120 mesh of mistake.Tincture of the present invention, powder are applied in combination, have it is clearing heat and detoxicating, antipruritic except wart the effect of, external curing enables drug to quickly infiltrate into below the epidermis, eliminates virus, removes old complaint, thoroughly cures verruca plana.Product of the present invention combination is unique, and according to clinical verification, treatment cycle is short, cheap, has no adverse reaction and any toxic side effect, and without puncturing wart, no pain can be used as the preferred Chinese materia medica preparation for the treatment of verruca plana.

Description

A kind of Chinese traditional medicine composition and preparation method thereof for treating verruca plana
Technical field
The present invention is to belong to prepared slices of Chinese crude drugs preparation technique field, especially a kind of Chinese traditional medicine composition and its system for treating verruca plana Preparation Method.
Background technique
Verruca plana (Flat Wart) is a kind of virus dermatopathy, is the viral neoplasm grown on the skin.It Pathogen is to be caused by papillomavirus HPV3 and HPV5 infection, this is a kind of DNA virus, people as verruca vulgaris It is its unique host, host cell is skin and mucomembranous epithelial cell, and virus is present in acantholysis cell, and can promote cell Active proliferation forms excipuliform skin vegetations.Verruca plana Chinese medicine claims " verruca plana ", it is believed that this disease is evil by affection of exogenous wind-heat poison, fights in skin And give birth to, the stagnated fire of internal cause irritability or anger are got angry, and liver-yang hyperactivity fire is dry, and skin is not flourish, and then qi depression to blood stasis phlegm coagulates caused by skin disease long.
Verruca plana be dermatology's common frdquently encountered disease, patient generally without sense of discomfort, occasionally have it is micro- itch, the course of disease is slow, sustainable more Year, some patientss can voluntarily improve.Disease time is longer, verruca plana serious pigmentation more easy to form.Verruca plana is sent out well In teenager, there is certain infectiousness, can be infected by close contact.Mainly by immediate contagion, but can also lead to Pollutant, such as needle, brush, towel indirect infection are crossed, in addition, wound is also to cause an important factor for infecting, immunity of organisms Low people is easy to infect verruca plana.Predilection site is face, the back of the hand and forearm etc., and fash feature is normal color of the leather, light red Color or the filbert flat papule for being higher by skin surface, dispersion or Assembled distribution, it is soft, top is smooth, its shape such as rice Grain is big to mung bean greatly, and for round or the flat protuberance of polygonal papule, surface is smooth, and boundary understands, it is seen that after scratching Autoinoculation phenomenon --- fash is arranged along scratch in beading, is substantive neoplasm.Modern medical studies have confirmed that it is all by Disease can lead to canceration caused by " human papilloma virus " infection, wherein with " epidermodysplasia verruciformis " canceration rate Highest, " condyloma acuminatum " take second place, and " verruca plana " canceration rate ranked third.
Western medicine there is no the drug of effectively radical cure verruca plana at present, and treating the common method of verruca plana, to be that physiotherapy includes cold Ointment and the oral traditional Chinese medicine such as jelly and laser therapy, injection hormone, oral antiviral medicament, external application dimension a acid, physiotherapy pair Skin has compared with strong stimulation, is easy scar, is easy recurrence.That there are therapeutic process is long for other methods, and effect is unobvious, costly The problems such as, biggish psychology and ailing pressure are caused to patient.Verruca plana develops to the danger for having canceration in advanced stage, patient's fervent phase It comes out to a kind of curative effect affirmative, Chinese materia medica preparation cheap, convenient to take.
Summary of the invention
Goal of the invention of the invention is to provide a kind of therapeutic process short, cheap, easy to use, can effectively eradicate flat The Chinese traditional medicine composition of flat wart.
The invention mainly includes being made by Raw material processing of the prepared slices of Chinese crude drugs, the Chinese traditional medicine composition include tincture and The formula of powder, the tincture is as follows by weight: 25-35 parts of psoralea corylifolia, 3-10 parts of the coptis, 50-70 parts of 75% ethyl alcohol;It is described Powder is 15-20 parts of borax of finely ground mistake 120 sieve.
Psoralea corylifolia, the coptis and the borax that the present invention uses is prepared slices of Chinese crude drugs grade raw materials.
Preparation method of the invention includes the following steps:
(1), psoralea corylifolia, the coptis for selecting high-quality, standardized processing prepared slices of Chinese crude drugs grade, accurately weigh psoralea corylifolia by prescribed dose 25-35 parts, 3-10 parts of the coptis;
(2), weighted psoralea corylifolia, the coptis are dried or is dried;
(3), the psoralea corylifolia after drying, the coptis are put into high speed medicinal material pulverizer, are ground into the medicinal powder of 120 mesh or more;
(4), psoralea corylifolia, coptis medicinal powder are poured into 50-70 parts of 75% ethyl alcohol, tincture are made, be sealed 10 days it is spare;
(5), finely ground by 15-20 parts of borax, 120 meshes are crossed, powder is made;
(6), tincture, powder are individually packed.
Step (6) of the present invention is specifically: with ultraviolet radiator by tincture, powder radiation sterilization, aseptically by tincture It is packaged into 80ml/ bottles of tincture, the powder of 15 grams/packet, forms tincture and powder combination, it is spare.
Side's solution of the present invention is as follows:
Psoralea corylifolia: acrid flavour, hardship, it is warm-natured.Return kidney, the spleen channel.Warming kidney and enhancing yang, receives gas antidiarrheal.For impotence and seminal emission, waist and knee crymodynia, kidney Void is breathed heavily, and is used for curing vitiligo, the card such as alopecia areata outside.
The coptis: bitter, it is cold in nature;Return heart, liver, gallbladder, stomach, large intestine channel;With heat-clearing and damp-drying drug, the effect of purging fire for removing toxin.It cures mainly When row heat toxin, typhoid fever, excess heat be vexed, feeling of fullness is vomitted inverse, bacillary dysentery, heat rush down abdominal pain, lung knot by, spit, be defeated in battle, lower blood, quench one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, ascarid The burning hot wound of parasitosis, pertussis, abscess of throat, acute conjunctivitis, aphtha, skin sore, eczema, soup.
Borax: it is sweet in flavor, salty, it is cool in nature, it attaches to the lung and stomach meridians.Have effects that clearing heat and detoxicating, detumescence anti-corrosion, clearing lung and eliminating phlegm, is used for Abscess of throat, aphthae, red eye, swell pain, ocular, phlegm-heat cough etc..
The present invention treats principle: Chinese medicine composition uses natural traditional Chinese medicine for raw material, with clearing heat and detoxicating, the flat superfluous wart that disappears, disappears Swollen hemostasis is principle, each dialectical compatibility of drug in component: psoralea corylifolia has good antitumor, anti-oxidant, antibacterial, anti-inflammatory, anti-suppression Effect that is strongly fragrant, adjusting estrogen level, the body's immunity that stops blooding, significantly increases, can be used for treating verruca plana, be main ingredient, yellow Company has the effects that antibacterial, anti-oxidant, anti-inflammatory, antitumor, Adjust-blood lipid, is adjuvant.2 medicines share, and play antibacterial anti-inflammatory altogether, put down and go to live in the household of one's in-laws on getting married The effect of wart that disappears stops blooding.Borax is clearing heat and detoxicating, anti-corrosion of reducing swelling, and cooperation psoralea corylifolia, the coptis enhance the work of clearing heat and detoxicating, the flat superfluous wart that disappears With borax powder external application friction wart, tincture, powder are worked along both lines, and are promoted wart rapid regression, are shortened treatment time.
Specifically used method of the present invention: tincture, powder are applied in combination, daily with tincture smear wart, one day 4-6 times, to After drug local absorption, it is sprinkled upon wart surface with powder daily, is gently rubbed 2-3 minutes every time, without puncturing wart skin, one It is 2-4 times.10 days as a treatment course.
The present invention is a kind of Chinese traditional medicine composition for treating verruca plana, belongs to external preparation, and easy to use, advantage is as follows:
1, the present invention use natural Chinese medicinal herb for raw material, tincture is made, powder is applied in combination, and first uses tincture clearing heat and detoxicating, after It is rubbed using powder and puts down the superfluous wart that disappears, worked along both lines, wart rapid regression can be promoted, shorten treatment time, effect is good, without bad Reaction and any toxic side effect.
2, the present invention, using no pain, avoids ointment pollution clothes without puncturing wart skin for local topical, Physiotherapy, injection treatment pain, the side effects such as oral medicine Time of Administration length, allergy irritating to stomach, easy to use, patient Compliance is good.
3, according to clinical verification, treatment cycle is short for product of the present invention, better than treatment method effect traditional at present, overcomes biography It rules to treat and is easy recurrence, stays scar, course for the treatment of length, costly disadvantage.
4, product of the present invention is cheap, and preparation process is relatively simple, is readily produced and promotes.
Specific embodiment
In order to better understand and implement the present invention, the present invention is further illustrated combined with specific embodiments below.
Embodiment 1
25 parts of prepared slices of Chinese crude drugs psoralea corylifolia, 5 parts of the coptis are weighed, dries or dries, the prepared slices of Chinese crude drugs after drying are put into high speed medicinal material It is ground into the medicinal powder of 120 mesh or more in pulverizer, the medicinal powder crushed is poured into 50 part of 75% ethanol solution, tincture is made Be sealed 10 days it is spare.15 parts of borax are weighed, finely ground, powder is made in 120 sieves excessively.Tincture, powder are shone with ultraviolet radiator It penetrates, sterilize, aseptically, be packaged into 80ml/ bottles of tincture, the powder of 15 grams/packet respectively, form tincture and powder combination It is spare.
Embodiment 2
30 parts of prepared slices of Chinese crude drugs psoralea corylifolia, 5 parts of the coptis are weighed, dries or dries, the prepared slices of Chinese crude drugs after drying are put into high speed medicinal material It is ground into the medicinal powder of 120 mesh or more in pulverizer, the medicinal powder crushed is poured into 60 part of 75% ethanol solution, tincture is made Be sealed 10 days it is spare.18 parts of borax are weighed, finely ground, powder is made in 120 meshes excessively.Tincture, powder are shone with ultraviolet radiator It penetrates, sterilize, aseptically, be packaged into 90ml/ bottles of tincture, the powder of 18 grams/packet respectively, form tincture and powder group It closes spare.
Embodiment 3
25 parts of prepared slices of Chinese crude drugs psoralea corylifolia, 3 parts of the coptis are weighed, dries or dries, the prepared slices of Chinese crude drugs after drying are put into high speed medicinal material It is ground into the medicinal powder of 120 mesh or more in pulverizer, the medicinal powder crushed is poured into 50 part of 75% ethanol solution, tincture is made Be sealed 10 days it is spare.12 parts of borax are weighed, finely ground, powder is made in 120 meshes excessively.Tincture, powder are shone with ultraviolet radiator It penetrates, sterilize, aseptically, be packaged into 80ml/ bottles of tincture, the powder of 12 grams/packet respectively, form tincture and powder combination It is spare.
The present invention is to be combined using said herbal medicine and given patient's external application, first clearing heat and detoxicating using tincture, the flat superfluous wart that disappears, after make With the flat superfluous wart that disappears of powder friction, works along both lines, wart rapid regression can be promoted, achieve the purpose that effectively to eradicate verruca plana.Now will 60 clinical observation experiment performance summaries are as follows:
1, clinical data: in 60 patients of this group, male 37, women 23;It is the oldest 55 years old, 12 years old minimum;The course of disease is most 60 days short, longest 7 years, majority was within 4 years.
2, diagnosis basis:
It is in rice at skin lesion with reference to " the judgement foundation of verruca plana " according to the regulation of " People's Republic of China's traditional Chinese medicine industry standard " For grain to the flat papule of sorghum grain size, surface is smooth, isolated to be dispersed in, and khaki or normal skin color or micro- itches;It is mainly in Exposure portion, such as face, the back of the hand;There is the characteristics of oneself inoculation, it is seen that isomorphic effect;It is apt to occur in teenager;Histopathology inspection Look into: spinous layer of epidermis is plump, papillomatous hyperplasia and hyperkeratinization, with parakeratosis.
3, criterion of therapeutical effect:
Recovery from illness: superfluous body subsides completely, or leaves momentary pigment spot, rear to restore skin true qualities, observes three months no relapse.
Effective: superfluous 60% or more body recession, the state of an illness is controlled.
It is invalid: to have no change using 2 weeks or more superfluous bodies, nothing is clearly better.
4, specific case:
Case one, patient Mr. Wang, female, 18 years old.1 year front left of patient starts to grow some perlarious parcels successively on hand, not bitterly Do not itch, identical as skin color, oneself has no effect using Compound Dexamethasone Acetate, is verruca plana by hospital diagnosis.Using of the invention real The traditional Chinese medicine composition for treating of example 1 is applied, wart is smeared with tincture daily and after drug local absorption, uses powder daily four times a day It is sprinkled upon wart surface, is gently rubbed 2 minutes every time, without puncturing wart skin, two times a day.10 days as a treatment course.Treatment ten After it, the obvious atrophy of pearl shape wart.After 30 days, pearl shape wart is calmed down substantially, and epidermis restores smooth, pigment gradually It is calm obvious thin out.Using 40 days, epidermis was smooth as before, substantially returned to healthy skin state.
Case two, patient Lee, male, 27 years old.There is in the grain of rice to the flat mound of jowar grain size right hand the back of the hand before patient 4 years Rash, surface is smooth, in flakes streak distribution, and pale red is micro- to itch.Using the traditional Chinese medicine composition for treating of the embodiment of the present invention 2, daily Wart is smeared with tincture and after drug local absorption, is sprinkled upon wart surface with powder daily four times a day, gently rubs 3 every time Minute, without puncturing wart skin, three times a day.10 days as a treatment course.After treating a course for the treatment of, pearl shape wart is obvious Atrophy is thoroughly cured after three courses for the treatment of, and clinical symptoms completely disappear, one Nian Weifu of Effect of follow-up visit by telephone.
Case three, patient Lee, male, 18 years old, both hands the back of the hand had in the grain of rice to the jowar grain flat papule of size, surface light Sliding, isolated to be dispersed in, normal skin tone is micro- to itch.Using the traditional Chinese medicine composition for treating of the embodiment of the present invention 1, wart is smeared with tincture daily Body after drug local absorption, is sprinkled upon wart surface with powder daily four times a day, gently rubs 3 minutes every time, without puncturing Wart skin, three times a day.10 days as a treatment course.After treating a course for the treatment of, effect is very good, cures after 3 courses for the treatment of, clinical Symptom completely disappears, and Effect of follow-up visit by telephone half a year does not recur.
Example IV, patient Mr. Wang, female, 43 years old, verruca plana was grown at both hands back, is in streak distribution, is seriously affected Hand is beautiful, and western medicines in treatment for many years, cannot be eradicated.Using the traditional Chinese medicine composition for treating of the embodiment of the present invention 2, tincture is used daily Agent smears wart and after drug local absorption, is sprinkled upon wart surface with powder daily six times a day, gently rubs 3 minutes every time, Without puncturing wart skin, four times a day.10 days as a treatment course.Using 10 days, verruca plana started to become smaller, and continued to use the hair Bright preparation, the atrophy of both hands verruca plana, skin surface calm down after 2 months, substantially return to healthy skin state.Follow-up after 3 years, not It recurs again.
Case five, patient it is high certain, female, 14 years old.Left hand arm starts to grow successively some perlarious small before patient 1 year Packet, pink, oneself has no effect using externally-applied ointment, is verruca plana by hospital diagnosis.Use the embodiment of the present invention 3 Traditional Chinese medicine composition for treating smears wart with tincture daily and after drug local absorption, is sprinkled upon wart with powder daily four times a day Surface gently rubs 3 minutes, without puncturing wart skin, two times a day every time.10 days as a treatment course.It is precious after treatment ten days The obvious atrophy of pearl wart.After 20 days, pearl shape wart is calmed down substantially, substantially returns to healthy skin state, follow-up It does not recur.
Embodiment six, patient Xiao, female, 23 years old, verruca plana was grown at left hand back, be in 2 streak distributions, take orally in Medicine, externally-applied ointment treatment for many years, cannot eradicate.Using the traditional Chinese medicine composition for treating of the embodiment of the present invention 2, applied daily with tincture Wart is smeared, six times a day, after drug local absorption, is sprinkled upon wart surface with powder daily, gently rubs 3 minutes, does not have to every time Wart skin is punctured, four times a day.10 days as a treatment course.Using 10 days, verruca plana started to become smaller, and continued to use the invention system Agent, the atrophy of both hands verruca plana, skin surface calm down after 2 months, substantially return to healthy skin state.Follow-up after 1 year, it is not multiple again Hair.
5, treatment results:
Collect 60 verruca plana patients, the age 12-55 years old, course of disease 1-7, male 37, women 23;It is the oldest It is 55 years old, 12 years old minimum;The course of disease is most 60 days short, and longest 7 years, majority was within 4 years.All 60 patients fully recover 46, and effective 13 Example, invalid 1, total effective rate 98.3%.Reasonable recipe of the present invention, compatibility is rigorous, as can be seen from the above data, the present invention There is significant curative effect and easy to use to verruca plana, approved by numerous verruca plana patients.
It should be noted last that: the above embodiments are only used to illustrate and not limit the technical solutions of the present invention, although ginseng It is described the invention in detail according to above-described embodiment, it will be apparent to an ordinarily skilled person in the art that: it still can be to this Invention is modified or replaced equivalently, without departing from the spirit or scope of the invention, or any substitutions, It is intended to be within the scope of the claims of the invention.

Claims (4)

1. a kind of Chinese traditional medicine composition for treating verruca plana, it is characterised in that: the Chinese traditional medicine composition includes tincture and powder, the tincture Formula it is as follows by weight: 25-35 parts of psoralea corylifolia, 3-10 parts of the coptis, 50-70 parts of 75% ethyl alcohol;The powder is finely ground mistake 15-20 parts of the borax of 120 meshes.
2. Chinese traditional medicine composition according to claim 1, it is characterised in that: the psoralea corylifolia, the coptis and borax are the prepared slices of Chinese crude drugs Grade raw material.
3. the preparation method of Chinese traditional medicine composition as described in claim 1, it is characterised in that include the following steps:
(1), psoralea corylifolia, the coptis for selecting high-quality, standardized processing prepared slices of Chinese crude drugs grade, accurately weigh psoralea corylifolia by prescribed dose 25-35 parts, 3-10 parts of the coptis;
(2), weighted psoralea corylifolia, the coptis are dried or is dried;
(3), the psoralea corylifolia after drying, the coptis are put into high speed medicinal material pulverizer, are ground into the medicinal powder of 120 mesh or more;
(4), psoralea corylifolia, coptis medicinal powder are poured into 50-70 parts of 75% ethyl alcohol, tincture are made, be sealed 10 days it is spare;
(5), finely ground by 15-20 parts of borax, 120 meshes are crossed, powder is made;
(6), tincture, powder are individually packed.
4. preparation method according to claim 3, it is characterised in that: step (6) tincture, powder is individually packed is: in nothing Tincture is distributed into the bottled of 80ml under the conditions of bacterium, powder is distributed into 15-20 grams of packaging.
CN201910331903.0A 2019-04-24 2019-04-24 A kind of Chinese traditional medicine composition and preparation method thereof for treating verruca plana Pending CN109876042A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758427A (en) * 2015-04-07 2015-07-08 邢继霞 Traditional Chinese medicine preparation for plane warts due to stagnation of heat-toxin and production method of traditional Chinese medicine preparation
CN107648553A (en) * 2017-09-25 2018-02-02 汪杰峰 Treat the Chinese medicine and preparation technology of flat wart

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758427A (en) * 2015-04-07 2015-07-08 邢继霞 Traditional Chinese medicine preparation for plane warts due to stagnation of heat-toxin and production method of traditional Chinese medicine preparation
CN107648553A (en) * 2017-09-25 2018-02-02 汪杰峰 Treat the Chinese medicine and preparation technology of flat wart

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