CN109862882A - 用于治疗皮肤真菌感染的方法和组合物 - Google Patents

用于治疗皮肤真菌感染的方法和组合物 Download PDF

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Publication number
CN109862882A
CN109862882A CN201780066597.1A CN201780066597A CN109862882A CN 109862882 A CN109862882 A CN 109862882A CN 201780066597 A CN201780066597 A CN 201780066597A CN 109862882 A CN109862882 A CN 109862882A
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CN
China
Prior art keywords
solution
antifungal agent
antiperspirant
treatment
terbinafine
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Pending
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CN201780066597.1A
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Chinese (zh)
Inventor
卡尔·F·尚巴赫
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26Aluminium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41921,2,3-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216Solid or semisolid forms
    • A61K8/022Powders; Compacted Powders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/87Application Devices; Containers; Packaging

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
CN201780066597.1A 2016-08-29 2017-08-22 用于治疗皮肤真菌感染的方法和组合物 Pending CN109862882A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662380787P 2016-08-29 2016-08-29
US62/380787 2016-08-29
PCT/US2017/047971 WO2018044621A1 (en) 2016-08-29 2017-08-22 Methods and compositions for treating cutaneous fungal infections

Publications (1)

Publication Number Publication Date
CN109862882A true CN109862882A (zh) 2019-06-07

Family

ID=59799468

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780066597.1A Pending CN109862882A (zh) 2016-08-29 2017-08-22 用于治疗皮肤真菌感染的方法和组合物

Country Status (8)

Country Link
US (1) US10251822B2 (https=)
EP (1) EP3503874A1 (https=)
JP (1) JP2019526631A (https=)
CN (1) CN109862882A (https=)
AU (1) AU2017320876B2 (https=)
CA (1) CA3034839A1 (https=)
MX (1) MX382357B (https=)
WO (1) WO2018044621A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111450128A (zh) * 2020-06-01 2020-07-28 王刚建 一种用于治疗脚气的药物

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10993890B2 (en) * 2018-03-15 2021-05-04 Pelli Skin Co., Llc Antifungal solution and foot wipe
KR102217617B1 (ko) * 2020-08-14 2021-02-19 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물
JPWO2022149300A1 (https=) * 2021-01-08 2022-07-14
KR20240069718A (ko) 2021-09-17 2024-05-20 모찌다 세이야쿠 가부시끼가이샤 액취 방지용 조성물
US20230414537A1 (en) * 2022-06-21 2023-12-28 Taro Pharmaceutical Industries Ltd. Topical naftifine compositions

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1024501A (en) * 1962-02-21 1966-03-30 Hardman & Holden Ltd Improvements relating to aerosol preparations
US4083954A (en) * 1975-04-04 1978-04-11 Kao Soap Co., Ltd. Aerosol composition
US5143718A (en) * 1987-09-15 1992-09-01 Riemann Trading Aps Antiperspirant composition
US5468473A (en) * 1994-02-09 1995-11-21 Innova Products, Inc. Antiperspirant for hands and feet
US20050238672A1 (en) * 2004-04-27 2005-10-27 Nimni Marcel E Antifungal drug delivery
WO2007039533A2 (en) * 2005-09-29 2007-04-12 Novartis Ag Antifungal composition
US20100056430A1 (en) * 2008-08-27 2010-03-04 Arnold Lester Treatment and Method for Eliminating or Reducing Foot Odor
EP2191828A1 (en) * 2007-09-05 2010-06-02 Pola Pharma Inc. Antifungal pharmaceutical composition
WO2010086732A1 (en) * 2009-01-30 2010-08-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Stable compositions for nail and skin treatment
US20120061267A1 (en) * 2010-09-14 2012-03-15 Sally Villalobos MediTowel Anti-Fungal Wipe
US20120114574A1 (en) * 2009-01-30 2012-05-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions for nail and skin treatment
RU2567036C1 (ru) * 2014-10-28 2015-10-27 Государственное бюджетное учреждение Республики Башкортостан "Научно-исследовательский технологический институт гербицидов и регуляторов роста растений с опытно-экспериментальным производством Академии наук Республики Башкортостан" Средство ухода за кожей, обладающее антифунгальными свойствами (варианты)

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JPS5824511A (ja) * 1981-07-17 1983-02-14 クラウス・リ−マン・アンド・カンパニ−・エイピ−エス 制汗用キツトとそのアプリケ−タ
US4551330A (en) * 1983-06-30 1985-11-05 Helene Curtis Industries, Inc. Skin and hair conditioner compositions and conditioning method
US7201914B2 (en) * 2002-05-17 2007-04-10 Xantech Pharmaceuticals, Inc. Combination antiperspirant and antimicrobial composition
JP2004351632A (ja) * 2003-05-27 2004-12-16 Meisei Sansho Kk 薬液含浸シート
US20060003654A1 (en) * 2004-06-30 2006-01-05 Lostocco Michael R Dispersible alcohol/cleaning wipes via topical or wet-end application of acrylamide or vinylamide/amine polymers
KR20060009093A (ko) * 2004-07-20 2006-01-31 송재신 염산 테르비나핀을 함유하는 분말 에어로졸 조성물
JP2007091643A (ja) * 2005-09-29 2007-04-12 Nippon Nohyaku Co Ltd 医療用抗白癬菌剤
WO2014134394A1 (en) * 2013-02-28 2014-09-04 Precision Dermatology, Inc. Topical formulations of corticosteroids with enhanced bioavailability
AR097959A1 (es) * 2013-10-09 2016-04-20 Riemann Trading Aps Composición antitranspirante
JP6975516B2 (ja) * 2014-06-30 2021-12-01 ロート製薬株式会社 外用組成物、化粧料、経皮吸収促進用組成物、外用組成物における有効成分の経皮吸収性を高める方法、経皮投与型医薬及び点眼用組成物

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1024501A (en) * 1962-02-21 1966-03-30 Hardman & Holden Ltd Improvements relating to aerosol preparations
US4083954A (en) * 1975-04-04 1978-04-11 Kao Soap Co., Ltd. Aerosol composition
US5143718A (en) * 1987-09-15 1992-09-01 Riemann Trading Aps Antiperspirant composition
US5468473A (en) * 1994-02-09 1995-11-21 Innova Products, Inc. Antiperspirant for hands and feet
US20050238672A1 (en) * 2004-04-27 2005-10-27 Nimni Marcel E Antifungal drug delivery
WO2007039533A2 (en) * 2005-09-29 2007-04-12 Novartis Ag Antifungal composition
EP2191828A1 (en) * 2007-09-05 2010-06-02 Pola Pharma Inc. Antifungal pharmaceutical composition
US20100056430A1 (en) * 2008-08-27 2010-03-04 Arnold Lester Treatment and Method for Eliminating or Reducing Foot Odor
WO2010086732A1 (en) * 2009-01-30 2010-08-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Stable compositions for nail and skin treatment
US20120114574A1 (en) * 2009-01-30 2012-05-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions for nail and skin treatment
US20120061267A1 (en) * 2010-09-14 2012-03-15 Sally Villalobos MediTowel Anti-Fungal Wipe
RU2567036C1 (ru) * 2014-10-28 2015-10-27 Государственное бюджетное учреждение Республики Башкортостан "Научно-исследовательский технологический институт гербицидов и регуляторов роста растений с опытно-экспериментальным производством Академии наук Республики Башкортостан" Средство ухода за кожей, обладающее антифунгальными свойствами (варианты)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111450128A (zh) * 2020-06-01 2020-07-28 王刚建 一种用于治疗脚气的药物

Also Published As

Publication number Publication date
AU2017320876A1 (en) 2019-03-07
EP3503874A1 (en) 2019-07-03
CA3034839A1 (en) 2018-03-08
MX382357B (es) 2025-03-13
US10251822B2 (en) 2019-04-09
US20180055745A1 (en) 2018-03-01
WO2018044621A1 (en) 2018-03-08
JP2019526631A (ja) 2019-09-19
MX2019002047A (es) 2019-10-04
AU2017320876B2 (en) 2022-07-07

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