CN109843301B - 用于递送治疗剂的含金属硅酸盐的多孔硅材料 - Google Patents

用于递送治疗剂的含金属硅酸盐的多孔硅材料 Download PDF

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CN109843301B
CN109843301B CN201780037192.5A CN201780037192A CN109843301B CN 109843301 B CN109843301 B CN 109843301B CN 201780037192 A CN201780037192 A CN 201780037192A CN 109843301 B CN109843301 B CN 109843301B
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composition
porous silicon
therapeutic agent
agent
silicon material
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Chinese (zh)
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CN109843301A (zh
Inventor
迈克尔·J·赛勒
康珍英
朱珍明
埃米莉·安格林
埃斯特尔·科恩
马修·斯卡拉克
桑吉塔·巴蒂亚
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Spinnaker Biosciences Inc
Massachusetts Institute of Technology
University of California San Diego UCSD
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Spinnaker Biosciences Inc
Massachusetts Institute of Technology
University of California San Diego UCSD
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
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CN201780037192.5A 2016-04-14 2017-04-14 用于递送治疗剂的含金属硅酸盐的多孔硅材料 Active CN109843301B (zh)

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CN202210547670.XA CN114949250A (zh) 2016-04-14 2017-04-14 用于递送治疗剂的组合物、药物组合物、制备方法以及用途

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US201662322782P 2016-04-14 2016-04-14
US62/322,782 2016-04-14
PCT/US2017/027772 WO2017181115A1 (en) 2016-04-14 2017-04-14 Porous silicon materials comprising a metal silicate for delivery of therapeutic agents

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CN202210547670.XA Pending CN114949250A (zh) 2016-04-14 2017-04-14 用于递送治疗剂的组合物、药物组合物、制备方法以及用途

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US (1) US20210177770A1 (cg-RX-API-DMAC7.html)
EP (1) EP3442540A4 (cg-RX-API-DMAC7.html)
JP (3) JP7093955B2 (cg-RX-API-DMAC7.html)
CN (2) CN109843301B (cg-RX-API-DMAC7.html)
AU (2) AU2017250300B2 (cg-RX-API-DMAC7.html)
CA (1) CA3021001A1 (cg-RX-API-DMAC7.html)
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JP7320303B2 (ja) * 2019-02-22 2023-08-03 レモネックス インコーポレイテッド 免疫活性もしくは癌の予防または治療用の医薬組成物
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CN116570721A (zh) * 2023-02-06 2023-08-11 四川农业大学 一种t-705@msn-rvg脑内药物递送载体及其制备方法
CN116510003B (zh) * 2023-06-20 2023-10-20 中国人民解放军军事科学院军事医学研究院 一种负载鼠疫菌rF1-V10蛋白的锰基纳米颗粒疫苗及其在抗鼠疫菌中的应用
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