CN109820785A - A kind of dewrinkling spot-eliminating whitening cream and preparation method thereof - Google Patents
A kind of dewrinkling spot-eliminating whitening cream and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a kind of dewrinkling spot-eliminating whitening cream and preparation method thereof, the raw material including following parts by weight: 16-20 parts of david poplar barks, 0.5-2 parts of peach blossoms, 2-4 parts of shelled pumpkin seeds, 0.5-2 parts of yulan magnolia, 0.5-2 portions of lavenders, 4-8 parts of coarse teas, 3-6 parts of propolis, 2-4 parts of persimmon leafs, 1-4 parts of Fructus Forsythiaes, 4-6 portions of Radix Glycyrrhizaes.Dewrinkling spot-eliminating whitening cream prepared by the present invention has many advantages, such as crease-resistant, dispelling stain, whitening bright color, smooth skin, solves the problems, such as that prior art products have a single function, are irritating to the skin.
Description
Technical field
The present invention relates to Skin whitening care cosmetics more particularly to a kind of dewrinkling spot-eliminating whitening cream and preparation method thereof.
Background technique
When skin declines to the protective capacities of body, regulating power, it may appear that the appearances such as color, color, form, texture
The change of integral status is embodied in and wrinkle occurs, form color spot, pigmentation, pachylosis etc..Color spot and pigmentation
The common problem of skin of face, the reason of pigmentation and color spot formation complicated multiplicity, as endocrine disorder, environmental pollution,
Ultraviolet light irradiation etc., while these reasons can also make skin elasticity and consolidation decline to form wrinkle.This outer skin lacks day
It is improper often to nurse or nurse, it is also possible to will cause that skin is obscure coarse, and body can not be discharged in time by being metabolized unsmooth skin bottom rubbish
Outside, accelerate the formation of pigmentation, color spot and wrinkle.Therefore, we it is necessary to skin do nursing suitably raise.
By adding various whitening spot-removing substances in cosmetics color spot is mitigated or eliminated, to reach whitening in people
The effect of nti-freckle.Whitening and freckle-removing product also brings many hidden dangers while bringing people's U.S..Whitening spot-removing earlier
Contain mercury and mercuric compounds or quinhydrones in product, since toxicity, irritation are larger, disabled addition is used.Currently on the market often
Whitening spot-removing ingredient includes arbutin, kojic acid, vitamin C and its derivative, is also deposited while generating whitening spot-removing effect
It is irritating to the skin effect in certain disadvantages, such as arbutin, user's impression of sensitive skin becomes apparent；Kojic acid has light
Sensibility is easy failure under highly concentrated acidic environment.Be added usually in cosmetics tartaric acid, tocopherol, vitamin E etc. at
Point, the crease-resistant function of Lai Zengjia cosmetics, but these ingredients are oxidized easily, to lose crease-resistant function.In existing product
The rare cosmetics that can have both dewrinkling spot-eliminating white-skinned face function and will not cause any harm to skin.
Metabolism is adjusted in natural plants active constituent rich in, promotes skin cell proliferation, has anti-oxidant
And remove free radical the effects of, gradually development and application in cosmetic field.Suitable active constituent is added in cosmetics
Subtle improvement result can be generated to skin, has the characteristics that without side-effects, significant effect, can be permeated by skin surface
To skin inner layer, fundamental issue is solved.
Summary of the invention
Therefore, for the above content, the present invention provides a kind of dewrinkling spot-eliminating whitening cream and preparation method thereof, solves existing skill
Art product function is single, the problem of being irritating to the skin.
In order to achieve the above objectives, the present invention is achieved by the following technical solutions: a kind of dewrinkling spot-eliminating whitening cream, including
The raw material of following parts by weight: 16-20 parts of david poplar barks, 0.5-2 parts of peach blossoms, 2-4 parts of shelled pumpkin seeds, 0.5-2 parts of yulan magnolia, 0.5-
2 portions of lavenders, 4-8 parts of coarse teas, 3-6 parts of propolis, 2-4 parts of persimmon leafs, 1-4 parts of Fructus Forsythiaes, 4-6 portions of Radix Glycyrrhizaes.
A further improvement is that: the raw material including following parts by weight: 18 parts of david poplar barks, 1 part of peach blossom, 3 parts of shelled pumpkin seeds,
1 part of yulan magnolia, 0.5 portion of lavender, 6 parts of coarse teas, 4.5 parts of propolis, 3 parts of persimmon leafs, 2.5 parts of Fructus Forsythiaes, 5 portions of Radix Glycyrrhizaes.
A further improvement is that: the step of preparation, is as follows:
(1) each raw material cleaned, dried, weighed and poured into micronizer by weight and crush；
(2) smashed raw material is sieved by 100-150 mesh screen, and the underproof raw material that is sieved continues to crush；
(3) the qualified each raw material of sieving pours into container after mixing, and 80% ethanol solution, the raw material and ethyl alcohol of mixing is added
The weight ratio of solution is then 1:15~20 are surpassed in 40-45 DEG C of immersion 40-60min under conditions of 70-80 DEG C of temperature
Sound wave extracts 1.5-2.5h, ultrasonic power 250-350W；
(4) it is filtered after ultrasonic wave extraction, obtains filtrate；
(5) filtrate for obtaining above-mentioned steps is condensed into paste mixture；
(6) it sterilizes, be distributed into canister.
Containing organic compounds such as kaempferia galamga acid, coumarin, trifolins in peach blossom, energy dredging the channel expands tip capillary
Blood villous themeda improves blood circulation, promotes skin-nourishing and oxygen supply, moisturizes the skin.Peach blossom also contains vitamin B1, vitamin B2, dimension
Multivitamins and the microelements such as raw element C, vitamin E, can prevent melanin chronic deposition in skin, can effectively eliminate
The chloasma of body surface, freckle, blackspot.In addition, peach blossom is rich in vegetable protein and a variety of amino acid in free state, it is easy by skin
Skin absorbs, beneficial to prevention and treatment dry skin, coarse and wrinkle etc..
The nutritional ingredients such as shelled pumpkin seed amino acid rich in, vitamin C, vitamin E and natural oil, these substances
Delicate skin can be nourished, delay skin aging can also inhibit pigment to accumulate, lighten the stain skin whitening.Shelled pumpkin seed may be used also
To enhance the antiallergy ability of skin, alleviates the skins such as dry skin and itch because of caused by skin allergy or infection and ask
Topic can allow the skin of people to keep a kind of normal and health state.
David poplar bark has the wind-dispelling row stasis of blood, controls wandering arthritis, tinea pedis, flutters damage hemostasis, pregnant dysentery, toothache, aphtha and other effects.It closes
It is on the books in the beauty functions Gu of david poplar bark, waxgourd seed benevolence, peach blossom, david poplar bark are mashed, grind into powder is mixed well, and is added
Enter honey to stir evenly, be made into the ball such as lichee size, long-term consumption has the effect of light spots and whitening, reference " legendary god of farming's book on Chinese herbal medicine
Through " in words are as follows: " long term usage it, face such as pattern."
Yulan magnolia can not only swelling and pain relieving, promoting blood circulation, beneficial lung, additionally it is possible to and it boosts metabolism, improves the sensibility of skin,
Skin whitening makes to have rosy cheeks, radiant, skin smooth is fine and smooth, delays senescence.The active matter that yulan magnolia contains can be rapid
Skin deep layer is permeated, cell moisture and nutriment are supplemented, hence it is evident that smooths smooth cut, lightens the stain, cellular energy is provided, accelerate blood
Liquid circulation, excludes skin waste toxins, can be used as cosmetic material use.
Lavender not only has ornamental value, but also is widely used in beauty, aromatotherapy, health care, medicine and other fields
On.Lavender is known as the good reputation of " balm " because of its safety and versatility.Lavender can be purple by reducing
The direct injury of UV radiation removes free radical, increases skin oxidation resistance, increases fibroblastic vigor, inhibiting to lead
The approach such as the protein expression of Apoptosis are caused to have the function that delay skin aging.The irradiation of excessive ultraviolet light can damage skin and
Skin barrier, and then lead to skin aging, there is color spot, wrinkle, pigmentation etc..Lavender can reduce skin to purple
The absorption intensity of UV radiation, delaying skin aging.Skin aging is a complicated process, with dry skin, pruritus, rouge
Property dermatitis of overflowing etc. has the connection in teiology.Effective active composition linalool in lavender has good anti-inflammatory effect, and
And the expression of proinflammatory inflammation factor can be inhibited.Studies have shown that linalool to Escherichia coli, staphylococcus aureus, hay bacillus,
The inhibitory effect of the bacteriums such as Pseudomonas aeruginosa is good.Contain higher superoxide dismutase (SOD) in Lavender, it can maximum limit
The free radical of degree removed in skin, blocks free radical to damage caused by skin histology, while having again to tyrosinase bright
The effects of aobvious inhibiting effect, thus can reduce cutaneous pigmentation, eliminates wrinkle of skin and senile plaque, delay skin aging.
Polyphenols rich in, collectively referred to as tea polyphenols in coarse tea extract mainly include flavanol compound, pattern
Glycoside, flavonols and phenolic acid class etc..Tea polyphenols have very strong inoxidizability and physiological activity, are the removings of human free radical
Agent.Research has shown that 1 milligram of tea polyphenols removing is equivalent to 9 microgram superoxides to the efficiency of the harmful excessive free radicals of human organism
Mutase (SOD), is much higher than other allied substances.Tea polyphenols have a blocking peroxidatic reaction of lipid, the effect of scavenging capacity enzyme,
To have anti-aging effect.The anti-aging effects of tea polyphenols are 18 times stronger than vitamin E.Tea polyphenols, which remove, has antioxidation
Outside, also there is bacteriostasis, such as have inhibiting effect to staphylococcus, Escherichia coli, hay bacillus.Tea polyphenols are water-soluble objects
Matter, the greasy of face can be removed by being washed one's face with it, restrain pore, had disinfection, sterilizing, resisting age of skin, reduced the purple in daylight
Damage and other effects of the UV radiation to skin.Tea polyphenols can stop ultraviolet light and remove the free radical of ultraviolet induction, thus
The normal function for protecting melanocyte, inhibits the formation of melanin.Inhibition is generated to lipid oxidation simultaneously, it is heavy to mitigate pigment
?.
Contain flavonoids in propolis, terpenoid substance, to various bacteria, fungi, the microorganisms such as virus have very strong suppression
System and killing effect and surprising anti-inflammatory effects.The flavonoids and cinnamic acid derivative and vitamin E that contain in propolis, dimension
Raw element C, vitamin A and trace elements of selenium, zinc, all have antioxidation.These substances are preventing cell senescence, mutation, color
Plain calm and color spot formation, excluding toxin etc. has fine effect, is rich in beeswax, pollen, resin and perfume (or spice) in propolis
The ingredients such as essential oil, wherein beeswax can prevent subcutaneous tissue hardening, keep skin elasticity, prevention and reduce wrinkle, and pollen can promote
Into skin metabolism, improve skin nutrition situation, the vigor of enhancing skin and to the resistance of extraneous poor environment, resin energy
Promote the synthesis of collagen and elastin laminin and dermal tissue can be activated, and essential oil can control fat secretion, remove blackhead
Acne are prevented and are lightened the stain.
Extractive from leaves of persimmon contain flavonoids, terpene, Coumarins, phytosterol, organic acid, fatty acid, vitamin and
The multiple compounds such as a variety of amino acid.Extractive from leaves of persimmon can maintain the eubolism of skin and musculature, resist free radical
Attack, so that the replacement of collagen is gone on smoothly, avoids skin from occurring wrinkle too early.Tyrosinase overacfivity is color spot etc.
Pigmented main reason, extractive from leaves of persimmon can hydrolyze the peptide bond of tyrosinase, to thoroughly inhibit the work of tyrosinase
Property, avoid color spot from being further formed.Extractive from leaves of persimmon can penetrate melanocyte film and in conjunction with nucleus, block melanin
Source of nutrition, with skin metabolism, melanin gradually will be decomposed and be disappeared.Phytosterol in persimmon extract is to skin
Skin has very high permeability, can keep skin surface moisture content, promotes skin metabolism, inhibits scytitis, can anti-day
The effect of shining erythema, skin aging.
Rutin, Hyperoside in forsythia suspense extraction containing high level, forsythin, oleanolic acid, ursolic acid, flavones
Class, procyanidine and tannin isoreactivity ingredient, have and remove superoxide radical, and the effect inhibited tyrosinase activity maintains machine
The good states of physiologic function of body can obviously desalinate the spot and wrinkle of face, play the role of crease-resistant anti-aging.Fructus Forsythiae
Extract is to typhoid bacillus, paratyphosum Bacterium, Escherichia coli, shigella dysenteriae, corynebacterium diphtheriae, comma bacillus, staphylococcus, hammer
Bacterium etc. has very strong inhibiting effect.
The principle active component of Radix Glycyrrhizae is triterpenoid and flavone compound, licoflavone can inhibit tyrosinase and
The activity of Dopa pigment tautomerase, to effectively inhibit the generation of melanin, whitening effect is preferable, action temperature and
Safe without toxic side effect.Licoflavone to bacteriums such as Escherichia coli, Bifidobacterium, Pseudomonas aeruginosa, staphylococcus aureuses and
The fungies such as aspergillus niger, aspergillus oryzae, bread mold, Mucor, Paecilomyces varioti have very strong inhibiting effect.
By using preceding solution, the beneficial effects of the present invention are:
Dewrinkling spot-eliminating whitening cream made of the present invention is tended to smear out and is absorbed, and improves skin texture, and smooth skin resists
Wrinkle, brighten, the effect of light spot it is obvious.On the basis of sufficiently having studied each raw material effect, and eliminate any raw material it
Between restriction or checking relation in five elements or it is incompatible a possibility that, the preferred type and weight proportion of raw material out makes phase interaction the effect of between various raw materials
With, mutually promote, preferably to play respective effect.Main active of the invention is extracted from natural plants,
It is safe and non-stimulating, it has no toxic side effect, epidermis, skin corium, subcutaneous tissue of the active constituent through facial skin permeation, activation is carefully
Born of the same parents inhibit the activity of tyrosinase, and melanin is inhibited to be formed, and improve chromatophore updating ability, reduce pigment deposition, promote color
Plain cell detachment enhances the autoimmunity of cell, improves metabolic function, improves skin self supporting capacity.In raw material
A variety of active ingredients there is natural fungistatic effect, such as tea polyphenols, flavones, linalool have bacterium, fungi apparent
Inhibiting effect can serve as the natural antiseptic agent in skin care item, and compared to addition chemical preservative, effect is more mild, pacifies
Entirely.The antioxidant mechanism of active constituent is different, for example, flavone compound can extra free radical in catching machine body,
And stable resonant structure blocking oxide is formed in itself；Vitamin C then can act on remaining oxygen in consumption system with oxygen, these
Substance with different antioxygenic properties is used cooperatively, and can be restored mutually, be regenerated oxidation-resistant active ingredient, and is different
For antioxidant after anti-oxidant, the free radical of generation, which can interact, produces new phenolic compound, continues to play anti-oxidant
Effect is shown generally as antioxidant effect enhancing.Tea polyphenols can be between the organic acid of no antioxidant activity, fatty acid
Hydrogen bond association forms big and stable hydrogen donor, improves the antioxidant activity of tea polyphenols.Tea polyphenols can be sent out with active oxygen species
Raw redox reaction, generates phenoxyl radicals, and vitamin C can restore phenoxyl radicals, and tea polyphenols is promoted to regenerate,
The two generates synergistic effect, slows down the loss of tea polyphenols.Dewrinkling spot-eliminating skin whitener made of various raw materials are reasonably combined can rise
To synergistic effect, crease-resistant, whitening, freckle effect are strong, have taken into account product the effect of property and safety well, have been not necessarily to
Chemical preservative is added, certain active constituents in raw material can play the role of antibacterial corrosion-resistant, while from melanin production
And the overall process of metabolism carries out comprehensive whitening spot-removing, is not easy to rebound.
Specific embodiment
Carry out the embodiment that the present invention will be described in detail below with reference to specific embodiment, how skill is applied to the present invention whereby
Art means solve technical problem, and the realization process for reaching technical effect can fully understand and implement.
Unless otherwise specified, the conventional hand that technological means employed in embodiment is well known to those skilled in the art
Section, used reagent and product are also available commercial.The source of agents useful for same, trade name and it is necessary to list it
Constituent person is indicated on the first occurrence.
Embodiment one
A kind of dewrinkling spot-eliminating whitening cream, the raw material including following parts by weight: 16 parts of david poplar barks, 0.5 part of peach blossom, 2 parts it is white
Shelled melon seed, 0.5 part of yulan magnolia, 2 portions of lavenders, 4 parts of coarse teas, 3 parts of propolis, 2 parts of persimmon leafs, 1 part of Fructus Forsythiae, 4 portions of Radix Glycyrrhizaes.
The step of preparation of the dewrinkling spot-eliminating whitening cream, is as follows:
(1) each raw material cleaned, dried, weighed and poured into micronizer by weight and crush；
(2) smashed raw material is sieved by 100 mesh screens, and the underproof raw material that is sieved continues to crush；
(3) the qualified each raw material of sieving pours into container after mixing, and 80% ethanol solution, the raw material and ethyl alcohol of mixing is added
The weight ratio of solution is 1:15, and in 40 DEG C of immersion 60min, ultrasonic wave extraction 1.5h is then carried out under conditions of temperature 70 C,
Ultrasonic power is 350W；
(4) it is filtered after ultrasonic wave extraction, obtains filtrate；
(5) filtrate for obtaining above-mentioned steps is condensed into paste mixture；
(6) it sterilizes, be distributed into canister.
Embodiment two
A kind of dewrinkling spot-eliminating whitening cream, the raw material including following parts by weight: 18 parts of david poplar barks, 1 part of peach blossom, 3 portions of white melons
Sub- benevolence, 1 part of yulan magnolia, 0.5 portion of lavender, 6 parts of coarse teas, 4.5 parts of propolis, 3 parts of persimmon leafs, 2.5 parts of Fructus Forsythiaes, 5 portions of Radix Glycyrrhizaes.
The step of preparation of the dewrinkling spot-eliminating whitening cream, is as follows:
(1) each raw material cleaned, dried, weighed and poured into micronizer by weight and crush；
(2) smashed raw material is sieved by 120 mesh screens, and the underproof raw material that is sieved continues to crush；
(3) the qualified each raw material of sieving pours into container after mixing, and 80% ethanol solution, the raw material and ethyl alcohol of mixing is added
The weight ratio of solution is 1:17, and in 42 DEG C of immersion 50min, ultrasonic wave extraction 2h is then carried out under conditions of 75 DEG C of temperature, is surpassed
Acoustic power is 300W；
(4) it is filtered after ultrasonic wave extraction, obtains filtrate；
(5) filtrate for obtaining above-mentioned steps is condensed into paste mixture；
(6) it sterilizes, be distributed into canister.
Embodiment three
A kind of dewrinkling spot-eliminating whitening cream, it is characterised in that: the raw material including following parts by weight: 20 parts of david poplar barks, 2 portions of peaches
Flower, 4 parts of shelled pumpkin seeds, 2 parts of yulan magnolia, 1 portion of lavender, 8 parts of coarse teas, 6 parts of propolis, 4 parts of persimmon leafs, 4 parts of Fructus Forsythiaes, 6 portions of Radix Glycyrrhizaes.
The step of preparation of the dewrinkling spot-eliminating whitening cream, is as follows:
(1) each raw material cleaned, dried, weighed and poured into micronizer by weight and crush；
(2) smashed raw material is sieved by 150 mesh screens, and the underproof raw material that is sieved continues to crush；
(3) the qualified each raw material of sieving pours into container after mixing, and 80% ethanol solution, the raw material and ethyl alcohol of mixing is added
The weight ratio of solution is 1:20, and in 45 DEG C of immersion 40min, ultrasonic wave extraction 2.5h is then carried out under conditions of 80 DEG C of temperature,
Ultrasonic power is 250W；
(4) it is filtered after ultrasonic wave extraction, obtains filtrate；
(5) filtrate for obtaining above-mentioned steps is condensed into paste mixture；
(6) it sterilizes, be distributed into canister.
Product effect assessment
(1) trial target: dewrinkling spot-eliminating whitening cream prepared by embodiment 1-3
(2) tested crowd and grouping: 200 faces have microgroove, certain position wrinkles are obvious, have color spot, the colour of skin obscure and
Skin health, the female subjects of no skin disease allergies 35~60 years old, are randomly divided into 4 groups, every group of 50 people.
(3) application method: after each group subject cleans face, suitable product is smeared in face, gently massage is until complete
Hypersorption is respectively used continuously 8 weeks using once sooner or later, tracks and records and have no adverse reaction in use process.
(4) clinical efficacy assessment effect evaluation method: is carried out by subject's naked eyes visual evaluation and professional to weigh
Amount.Feedback result after subject's Evaluation product 8 weeks is shown in Table 1-3.Spot-removal function assessment and standards of grading: it is required before assessment every time
Interior (21 DEG C ± 1 DEG C of temperature, humidity 45% ± 5%) the rest 30min of subject in constant temperature and humidity, indoor light condition guarantor
Hold it is consistent, the 4th week after using preceding and use, each follow-up in the 8th week it is primary, each follow-up selects same position to be used as and tests target portion
Position judges color spot by the variation of the color spot shade and area of subject's face appointed part before and after observation product use
Improved degree.Spot-removal function clinical assessment the results are shown in Table 4.
Spot-removal function standards of grading: 0=color and/or area without improvement or are deteriorated；1=has slight improvement, and color is a little
Thin out and/or area subsides less than 30%；2=moderate improves, and color has thin out and/or area to subside more than or equal to 30%,
Less than 60%；The more apparent improvement of 3=, color is more apparent thin out and/or area subsides more than or equal to 60%, less than 90%；4=
It is obviously improved or improves completely, color is more apparent thin out and/or area subsides more than or equal to 90%.Wherein scoring is 1,2,3
Divide and is considered as effectively；4 points of scoring, is considered as clinical cure.
1 embodiment 1 of table prepares the feedback conclusive table on probation of product
2 embodiment 2 of table prepares the feedback conclusive table on probation of product
3 embodiment 3 of table prepares the feedback conclusive table on probation of product
4 spot-removal function clinical assessment result of table
By table 1 to table 3 it is known that subject indicates after being used continuously the dewrinkling spot-eliminating whitening cream 8 weeks, color on the face
Spot, wrinkle significantly reduce, and dewrinkling spot-eliminating effect is good, and there are also the effects of whitening bright color, and the salubrious, light using rear skin
It is sliding, adhere to that using effect becomes apparent from for a long time, using subject feedback's evaluation after 8 weeks better than the Feedback Evaluation after using 4 weeks.Together
When subject in there is no an example the adverse reactions such as skin allergy, red and swollen phenomenon occur.As shown in Table 4, it using after product 4 weeks, dispels
Spot effective percentage reaches 82% or more；After 8 weeks, effective percentage reaches 96% or more.
The foregoing descriptions are merely the embodiment using this origination techniques content, any those skilled in the art use this wound
Make done modifications and changes, all belong to the scope of the patents of this creation opinion, and is not limited to those disclosed embodiments.
Claims (3)
1. a kind of dewrinkling spot-eliminating whitening cream, it is characterised in that: the raw material including following parts by weight: 16-20 parts of david poplar barks, 0.5-
2 parts of peach blossoms, 2-4 parts of shelled pumpkin seeds, 0.5-2 parts of yulan magnolia, 0.5-2 portions of lavenders, 4-8 parts of coarse teas, 3-6 parts of propolis, 2-4 parts
Persimmon leaf, 1-4 part Fructus Forsythiae, 4-6 portions of Radix Glycyrrhizaes.
2. a kind of dewrinkling spot-eliminating whitening cream according to claim 1, it is characterised in that: the raw material including following parts by weight:
18 parts of david poplar barks, 1 part of peach blossom, 3 parts of shelled pumpkin seeds, 1 part of yulan magnolia, 0.5 portion of lavender, 6 parts of coarse teas, 4.5 parts of propolis, 3
Part persimmon leaf, 2.5 parts of Fructus Forsythiaes, 5 portions of Radix Glycyrrhizaes.
3. the preparation method of -2 described in any item dewrinkling spot-eliminating whitening creams according to claim 1, it is characterised in that: the step of preparation
It is rapid as follows:
(1) each raw material cleaned, dried, weighed and poured into micronizer by weight and crush；
(2) smashed raw material is sieved by 100-150 mesh screen, and the underproof raw material that is sieved continues to crush；
(3) the qualified each raw material of sieving pours into container after mixing, and 80% ethanol solution, the raw material and ethanol solution of mixing is added
Weight ratio be then 1:15~20 in 40-45 DEG C of immersion 40-60min carry out ultrasonic wave under conditions of 70-80 DEG C of temperature
Extract 1.5-2.5h, ultrasonic power 250-350W；
(4) it is filtered after ultrasonic wave extraction, obtains filtrate；
(5) filtrate for obtaining above-mentioned steps is condensed into paste mixture；
(6) it sterilizes, be distributed into canister.
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Application publication date: 20190531 |
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| RJ01 | Rejection of invention patent application after publication |