CN109777639A - It is a kind of for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene and preparation method thereof - Google Patents
It is a kind of for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene and preparation method thereof, including, in terms of mass fraction, 0.2~5 part of quaternary ammonium salt cationic compound, 0.01~2 part of guanidine compound, 0.1~1 part of intercalating agent, 5~18 parts of fatty alcohols, 2~10 parts of activating agent, remainder are water.The present invention by cation activity object guanidine and quaternary ammonium salt active factors combination after, formed have complementary advantages the effect of and fatty alcohol, activating agent, chelating agent intersection composite design, formed multiple activities because of subsystem, the fast wide sterilization spectrum of sterilization speed is easy to use；Corrosion inhibition for metal ability is strong, and product and technology is enable preferably to apply disinfection and hygiene in the public places such as family, hospital, hotel air-conditioning, food processing equipment, general body surface.
Description
Technical field
The invention belongs to disinfecting detergent technical fields, and in particular to one kind is used for air-conditioning and general object hard surface
Disinfection and the preparation of hygiene and preparation method thereof.
Background technique
The air-conditioning of family, public environment, workshop, research department, farm etc. becomes increasingly popular, and is crowd using frequent
Intensive communication area and germ, virus, dust silted land populated regions, easily cause to hand between the mankind and other animals
Fork infection, epidemic disease are spread unchecked.The fungicide active ingredient of current air-conditioning and general surface disinfection agent is usually simple
DP300, PCMX, quaternary ammonium salt, alcohols or guanidine active component, prepared preparation fungicidal spectrum is narrow, with germs and viruses
Variation development, drug resistance is obvious, and bactericidal activity is insufficient, and when preparation practical application needs longer sterilizing time, and product is caused to make
Used time can not accomplish it is convenient and efficient, with the common people and entire society's consumption life level increasingly improve and generate to hygiene and health
Product proposes the requirements at the higher level that effect is used for product, and currently marketed product and technology are actually not achieved again
This objective demand.
To change current relatively backward product development technology and applying design level, air-conditioning of new generation and general object are developed
Body surface disinfectant realizes the best effect of product, using more convenient, is that this field needs to make up the defect of existing product
The technical issues of solution.
Summary of the invention
The purpose of this section is to summarize some aspects of the embodiment of the present invention and briefly introduce some preferable implementations
Example.It may do a little simplified or be omitted to avoid our department is made in this section and the description of the application and the title of the invention
Point, the purpose of abstract of description and denomination of invention it is fuzzy, and this simplification or omit and cannot be used for limiting the scope of the invention.
In view of above-mentioned technological deficiency, the present invention is proposed.
Therefore, as one aspect of the present invention, the present invention overcomes the deficiencies in the prior art, provides a kind of use
In air-conditioning and the disinfection of general object hard surface and the preparation of hygiene.
In order to solve the above technical problems, the present invention provides the following technical scheme that a kind of hard for air-conditioning and general object
The preparation of surface sterilization and hygiene comprising, quaternary ammonium salt cationic compound, guanidine compound, intercalating agent, fatty alcohol
Class, activating agent, water；
Wherein, in terms of mass fraction, 0.2~5 part of quaternary ammonium salt cationic compound, 0.01~2 part of guanidine compound, chelating
0.1~1 part of agent, 5~18 parts of fatty alcohols, 2~10 parts of activating agent, remainder are water；
The quaternary ammonium salt cationic compound includes: dimethyl double lauryl ammonium chlorides, dodecyl dimethyl ethylbenzene
The double certain herbaceous plants with big flowers ammonium chlorides of oxygen ethyl phosphonium bromide ammonium, dimethyl, the double certain herbaceous plants with big flowers base ammonium bromides of dimethyl, the double certain herbaceous plants with big flowers base ammonium carbonates of dimethyl, diethyl
Double dodecyl ammonium carbonates, dimethyl double tetradecyl ammonium chloride, dimethyl double hexadecyl ammonium chloride, benzethonium chlorides, benzyl rope
One or more of bromine ammonium.
It is excellent as one kind of the present invention for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene
Select scheme: the guanidine compound includes: spreading out for the derivative of poly hexamethylene biguanide or its salt, polyhexamethylene list guanidine or its salt
Biology is one such or several.
It is excellent as one kind of the present invention for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene
Select scheme: the activating agent includes: alkyl glycosides, propyl betaine, empgen BB, fatty alcohol polyoxyethylene ether, oxygen
Change one or more of cocamidopropyl propyl amide amine, polyvinyl alcohol 400, polyvinyl alcohol 600.
It is excellent as one kind of the present invention for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene
Select scheme: the fatty alcohols includes: ethyl alcohol, ethylene glycol, propyl alcohol, isopropanol, propylene glycol, glycerine, butanol, 1,3-BDO
One or more of.
It is excellent as one kind of the present invention for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene
Select scheme: the intercalating agent includes: ethylenediamine tetra-acetic acid, disodium ethylene diamine tetraacetate, tetrasodium ethylenediamine tetraacetate, ethylenediamine tetraacetic
One or more of potassium acetate sodium, B,EDTA, five sodium of aminotrimethylene phosphoric acid.
It is excellent as one kind of the present invention for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene
It selects scheme: further including, pigment and/or essence；In terms of mass fraction, 0~1 part of pigment, 0~1 part of essence.
As another aspect of the present invention, the present invention overcomes the deficiencies in the prior art, provides described in preparation
For air-conditioning and the disinfection of general object hard surface and the method for the preparation of hygiene.
In order to solve the above technical problems, the present invention provides the following technical scheme that described is used for air-conditioning and general object
The method of the preparation of hard surface disinfection and hygiene comprising,
Add water to reaction kettle；
Intercalating agent is added in reaction kettle under stirring, stirring heats up and controls at 30 DEG C~70 DEG C；
The bioactive agent composition is added；
The fatty alcohols is added, being sufficiently stirred is completely dispersed it uniformly；
It the guanidine compound is added is sufficiently stirred and make it completely dissolved；
The quaternary ammonium salt cationic compound is added to make it completely dissolved and be uniformly dispersed, flow back 10~20min；
Acidometer accurate measurements are used at 25 DEG C of solution temperature, and adjust the pH value of solution between 5.0~8.0；
Water is added, stirs evenly, flow back 10~20min.
As preparation of the present invention for air-conditioning and the disinfection of general object hard surface and the side of the preparation of hygiene
A kind of preferred embodiment of method: further including, and essence and/or pigment is added.
Beneficial effects of the present invention: the present invention passes through the cation activity object of two kinds of different structures and property: guanidine and season
Ammonium salt class active factors combination, have complementary advantages and fatty alcohol, activating agent, chelating agent intersection composite design, form multiple work
Sex factor synergy system makes it generate excellent sterilization bioactivity, preferable corrosion inhibition for metal ability, while the stability of preparation mentions
Non-stimulated, safety and environmental protection high, nontoxic to the human body, can expand application field, make it more easily in public affairs such as family, hospital, hotels
The disinfection of place air-conditioning, food processing equipment, environment and general body surface and hygiene use altogether.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, right combined with specific embodiments below
A specific embodiment of the invention is described in detail.
In the following description, numerous specific details are set forth in order to facilitate a full understanding of the present invention, but the present invention can be with
Implemented using other than the one described here other way, those skilled in the art can be without prejudice to intension of the present invention
In the case of do similar popularization, therefore the present invention is not limited by the specific embodiments disclosed below.
Secondly, " one embodiment " or " embodiment " referred to herein, which refers to, may be included at least one realization side of the invention
A particular feature, structure, or characteristic in formula." in one embodiment " that different places occur in the present specification not refers both to
The same embodiment, nor the individual or selective embodiment mutually exclusive with other embodiments.
Thimerosal of the present invention includes following ingredient and weight: 0.2~5 part of quaternary ammonium salt cationic compound, guanidine
0.01~2 part of compound, 0.1~1 part of intercalating agent, 5~18 parts of fatty alcohols, 2~10 parts of activating agent, remainder are water.The disinfection
State of the agent when pigment is not added is colourless or light yellow transparent liquid, and pH value of solution is 5~8.It, can be using each after the completion of preparation
The disinfection and cleaning of the general body surface such as class air-conditioning, furniture, clothing, floor, bathroom, raising pets environment；
Quaternary ammonium salt cationic compound includes: dimethyl double lauryl ammonium chlorides, dodecyl dimethyl ethylbenzene oxygen second
The double certain herbaceous plants with big flowers ammonium chlorides of base ammonium bromide, dimethyl, the double certain herbaceous plants with big flowers base ammonium bromides of dimethyl, the double certain herbaceous plants with big flowers base ammonium carbonates of dimethyl, diethyl double ten
Dialkyl group ammonium carbonate, dimethyl double tetradecyl ammonium chloride, dimethyl double hexadecyl ammonium chloride, benzethonium chloride, benzyl rope bromine ammoniums
One or more of, as active constituent.
Guanidine compound includes the derivative of the derivative of poly hexamethylene biguanide or its salt, polyhexamethylene list guanidine or its salt
It is one such or several, as active constituent.
Activating agent includes: alkyl glycosides (alkyl carbon number 8~10), propyl betaine, empgen BB, poly alkyl alcohol
Ethylene oxide ether (AEO3), fatty alcohol polyoxyethylene ether (AEO9), oxidation cocamidopropyl propyl amide amine (CAO30), polyvinyl alcohol 400,
The mixture of one or more of polyvinyl alcohol 600, as active auxiliary element.
Fatty alcohols include: ethyl alcohol, ethylene glycol, propyl alcohol, isopropanol, propylene glycol, glycerine, butanol, in 1,3-BDO
One or more kinds of mixtures, as solvent and synergist.
Intercalating agent includes: ethylenediamine tetra-acetic acid, disodium ethylene diamine tetraacetate, tetrasodium ethylenediamine tetraacetate, ethylenediamine tetrem
One or more mixtures of sour potassium sodium, B,EDTA, five sodium of aminotrimethylene phosphoric acid, it is auxiliary as synergy
Help material.
Embodiment 1:
In terms of mass fraction, 16 parts of deionized water are weighed, is injected into reactor, under stiring, ethylenediamine tetrem is added
0.2 part of acid disodium, temperature control is at 40 DEG C, after the completion of dissolution, is added 4 parts of fatty alcohol polyoxyethylene ether (AEO9), propylene glycol 11 is added
Part, it constantly is being added with stirring 0.20 part of poly hexamethylene biguanide, until it is completely dissolved, 5 parts of benzethonium chloride of addition flows back
20 minutes, acidometer accurate measurements are used at 25 DEG C of solution temperature, and adjust the pH value of solution between 5.0~7.5.It is added
64 parts of remaining deionized water, 1 part of pigment, stirs evenly by 1 part of essence, flows back 20 minutes, obtains the colourless liquid of clear
Product.
The different dosage form such as aerosol, spray, emulsion can be prepared into according to different use purposes.
Embodiment 2:
In terms of mass fraction, 20 parts of deionized water are weighed, is injected into reaction kettle, under stiring, ethylenediamine tetrem is added
0.2 part of acid, temperature control is at 35 DEG C, after the completion of dissolution, is added (600) 3 parts of polyvinyl alcohol, is added 12 parts of glycerine, is constantly stirring
2 parts of ammonium carbonate of lower addition polyhexamethylene list guanidine is mixed, until it is completely dissolved, dodecyl dimethyl ethylbenzene oxygen bromic ether is added
Change 4 parts of ammonium, flow back 20 minutes, acidometer accurate measurements are used at 25 DEG C of solution temperature, and adjust the pH value of solution 5.0~
Between 7.5.60 parts of remaining deionized water is added, 1 part of essence, 1 part of pigment, stirs evenly, flows back 10 minutes, it is saturating to obtain clarification
Bright colourless liquid.
The different preparation type such as aerosol, spray, emulsion can be prepared into according to different use purposes.
Embodiment 3:
1, in terms of mass fraction, reaction kettle first is added to by 85 parts of deionized water.
2,0.1 part of EDTA4Na intercalating agent is added in reaction kettle under stirring, stirring heats up and controls at 70 DEG C.
3, the CAO30 bioactive agent composition of 5 parts of metering is added while stirring.
4,5 parts of glycerine of metering are added while stirring, being sufficiently stirred is completely dispersed it uniformly.
5, the 0.01 part of hexamethylene compound accurately measured is added while stirring and is sufficiently stirred makes it
It is completely dissolved.
6, the double myristyl carbonic acid quaternized ammoniums of the 0.2 part of diethyl accurately measured are added while stirring to make it completely dissolved
Be uniformly dispersed.Flow back 15min.
7, acidometer accurate measurements are used at 25 DEG C of solution temperature, and adjust the pH value of solution between 5.0~7.0.
8,0.4 part of fragrance and 0.6 part of pigment and 20 parts of remaining deionized water is added, and stirs evenly, flows back
15min.Final products are colourless or brown yellow transparent liquid.
Embodiment 4:
1, in terms of mass fraction, reaction kettle first is added to by 20 parts of deionized water.
2,0.1 part of EDTA4Na intercalating agent is added in reaction kettle under stirring, stirring heats up and controls at 41 DEG C.
3, the CAO30 bioactive agent composition of 5 parts of metering is added while stirring.
4,5 parts of glycerine of metering are added while stirring, being sufficiently stirred is completely dispersed it uniformly.
5, the 0.01 part of hexamethylene compound accurately measured is added while stirring and is sufficiently stirred makes it
It is completely dissolved.
6, the double myristyl carbonic acid quaternized ammoniums of the 0.2 part of diethyl accurately measured are added while stirring to make it completely dissolved
Be uniformly dispersed.Flow back 15min.
7, acidometer accurate measurements are used at 25 DEG C of solution temperature, and adjust the pH value of solution between 5.0~7.0.
8,0.4 part of fragrance and 0.6 part of pigment and 60 parts of remaining deionized water is added, and stirs evenly, flows back
15min.Final products are colourless or brown yellow transparent liquid.
The killing logarithm that quaternary ammonium salt of the present invention combines to indicator bacteria with guanidine active factors is shown in Table 1.The active constituent of table 1
It combines corresponding different tests active component and 2 is shown in Table to rate of metal corrosion test data R value.Non- guanidine and quaternary ammonium salt or guanidine with
The indicator bacteria of sterilizing rate screening test after non-quaternary ammonium salt active factors combination kills logarithm and is shown in Table 3.
1 guanidine active factors of table combine the killing logarithm comparative analysis to indicator bacteria with all kinds of active factors
1, according to 2002 editions suspension method quantitative disinfecting tests of Ministry of Public Health's disinfection technology standard；
2, time of contact t=1min；
3, other components are the deionized waters of same ratio.
As can be known from the above table, the active factors compatibility group of quaternary ammonium salt or addition other the bactericidal activity factors and guanidine is not added
After conjunction, then by its bactericidal activity of verification experimental verification deficiency and national standard is not achieved；Preferred quaternary ammonium salt and suitable guanidine or guanidine
Excellent sterilization bioactivity can be generated after salt combination；With 1 hydrophilic radical and more in double-chain quaternary ammonium salt class disinfectant structure
A hydrophobic grouping has relatively good water solubility and dissolution and penetrating power to organic matter, possesses good reduction solution table
The ability of face tension also has the detrimental effect for resisting anion active ability, hard water, albumen organic matter etc., furthermore its foam
Also seldom.It is not only water-soluble fabulous and do not widened antimicrobial spectrum also while maintaining good bactericidal effect by water quality impact.
Quaternary ammonium salt, guanidine and its salt are positively charged after hydrolyzing in water, are adsorbed in antimicrobial surface, form ion micelle, gradually penetrate into thin
The lipoid layer and albumin layer of cytoplasm make cellular content exosmose to change permeability of cell membranes, lead to cell death.Together
When solidify cell protein again, make bacterium biological enzyme and its structural proteins denaturation, destroy the metabolism of microorganism and make endochylema egg
White, after birth precipitating, bacterium are unable to normal existence, finally kill microorganism.The related suspension method killing of health ministry is caused a disease micro-
Biological standard be large intestine, Pseudomonas aeruginosa kill logarithm have to be larger than 5；Bai Nian can determine whether qualification after being greater than 4.
The corresponding different tests active component of table 2 is to rate of metal corrosion test data R value
1, foundation: " disinfection technology standard " (version in 2002) 2.2.4 is detected.
2, detect material: carbon steel (specification is shown in GB 700-65)；Copper (specification is shown in GB 2060-80)；(specification is shown in GB to aluminium
1173-74)；Stainless steel (specification is shown in GB 1220-75).Sheet metal immerses the closed immersion 72Hrs of solution, to sheet metal
After reason and weighing, rate of corrosion is calculated.
3, the no corrosion of national standard R < 0.0100；The mild corrosion of 0.0100 < R < 0.100；The moderate of 0.100 < R < 1.00
Corrosion；The corrosion of the severe of R > 1.00.
The non-guanidine of table 3 combined with quaternary ammonium salt or guanidine with non-quaternary ammonium salt active factors after killing logarithm
1 according to 2002 editions suspension method quantitative disinfecting tests of Ministry of Public Health's disinfection technology standard；
Time of contact t=1min；
2. other components are identical deionized waters.
As can be known from the above table, it does not add guanidine or the other bactericidal activity factors of addition is combined with quaternary ammonium salt；Or addition is new
Activating agent and guanidine active component, test result shows that composition bactericidal activity is insufficient and national standard is not achieved；Examination
Testing data proves preferred guanidine and preferred a part of quaternary ammonium salt and can generate excellent sterilization work in reasonable ratio compatibility
Property.
The different activating agent of table 4 influences data analysis to the killing logarithm that quaternary ammonium salt is combined with guanidine active factors
As can be known from the above table, it does not add table work or the other different tables of addition is living to guanidine and quaternary ammonium salt bactericide active factors
Combination has significant impact, will cause bactericidal activity deficiency and national standard is not achieved, the reason is that part table work may be to sun
The functional group of ionic surfactant and entire molecule have absorption or even package action, seriously restrict and fettered bactericidal activity because
The bactericidal activity of son；What preferred table was lived generates excellent sterilization bioactivity to guanidine and quaternary ammonium salt active factors group credit union；Machine
Reason may be the suitable table work of addition can be generated with the chemical structure of sterilization factors it is complementary combined with effect, on the one hand make
Dissolution dispersibility enhancing in the water of sterilization factors, followed by suitable table work can promote sterilization factors in the suction of cell surface
Attached infiltration and the promotion of transparency are conducive to sterilization factors and attack the expansion of the organ inside pathogenic bacteria and influence the
Three aspect tables appropriateness living is not only water-soluble added with the side effect for resisting organic matters such as anion active agent, hard water, albumen etc.
Enhancing and not by water quality impact, the sterilization test suspension method national standard that the Ministry of Public Health formulates be large intestine, green pus kills logarithm must
5 must be greater than；It is qualified that Bai Nian is greater than 4 judgements.
5 alcohol of table, chelating agent kill the test data of logarithm to quaternary ammonium salt and guanidine active factors combined effect
By to biguanides quaternary ammonium salt active component and biguanides non-quaternary ammonium salt isoreactivity combined system contrast design, then lead to
Cross add the components such as different table work, alcohols, chelating agent intersect actual tests measure its bioactivity and without addition table it is living or
It adds other table work and combines contrast design with the bactericidal activity of guanidine and quaternary ammonium salt etc., then sentenced by the experimental study of system
Fixed: bactericidal activity is insufficient and national standard is not achieved；Preferred table is living to generate excellent sterilization life to guanidine and quaternary ammonium salt group credit union
Object activity；Mechanism may be addition the suitable table work of compatibility can with the chemical structure of sterilization factors have it is complementary combined with imitate
It answers, on the one hand enhances the dissolution dispersibility in the water of sterilization factors, while on the other hand, suitable table work can promote to sterilize
The factor is conducive to sterilization factors to pathogenic bacteria in the adsorption and permeation of cell surface and promotion to bacterial cell membrane transparency
The expansion of internal structure tissue is attacked.Third aspect mechanism may be table appropriateness living added with resisting anion active agent, hard
The side effect of the organic matters such as water, albumen etc., not only water-soluble and liposoluble dispersibility enhances and not by the whole function of water quality impact
The promotion of effect；Chelating agent and preferred table it is living cationic active agent can be combined into bactericidal activity height corrosion inhibiting ability obtains simultaneously
Stablize and reinforce, mechanism is that the auxiliary molecules in solution can form book film on surfaces such as metals, influences the generation of polarization phenomena, can
The corrosion of metal material can be prevented again to control the microbial reproduction of body surface for a long time, this is also the new hair that we test
It is existing；Calcium and magnesium plasma can be complexed in chelating agent to a certain extent, generate inhibiting effect to the bioactivity of bacterial enzyme, assist simultaneously
Sterilization factors are helped to enhance bactericidal effect, this is also the new discovery by a large number of experiments.
The corresponding test group antiseptic solution of 6 laboratory's technique of table preparation is to rate of metal corrosion test data R value
As can be known from the above table, addition poly hexamethylene biguanide it is appropriate and with double long chain quaternaries, surfactant and auxiliary
The combination of the appropriate ratio of preparation, rate of metal corrosion reduce, and can produce the corrosion inhibiting ability of excellent metal.
7 preferred composition preparation of table is to surface disinfection test result
According to Ministry of Public Health's disinfectant technical specification, bactericidal effect time t:1min.
The scoring of 8 pairs of the table stimulate the reaction of family's rabbit skin one time
By to the stimulate the reaction data analysis of family's rabbit skin, this this disinfecting and there is no any thorn to family's rabbit skin
Swash property.
Toxicology inspection result:
1, sample LD oral to female mice50(95% fiducial limit) is 4300 (2950-6260) mg/kgb.wt., belongs to low toxicity
Grade；Sample LD oral to male mice50(95% fiducial limit) is 5840 (4300-7940) mg/kgb.wt., the true nontoxic grade in border；
2,5 times of highest application strength solution male and female mouse oral LD50Value is all larger than 5000mg/kgb.wt., and true border is nontoxic
Grade；
3, mice bone marrow micronucleus:
The tested metering of male and female mouse respectively reaches 2150 and 2929mg/kgb.wt, and it is thermophilic to mouse bone marrow cells more not detect sample
It incarnadines cell and causes micronucleus effect.
The present invention is combined by the cation activity object guanidine and quaternary ammonium salt active factors of two kinds of different structures and property,
Have complementary advantages and fatty alcohol, activating agent, chelating agent intersection composite design, form the multiple activities factor and synergy system, make
It generates excellent sterilization bioactivity, corrosion inhibition for metal ability, at the same stability improves, toxicity reduces, it is safe to the human body it is reliable,
To natural environmental protection, product and technology are mainly used in the public places such as family, hospital, hotel air-conditioning, food processing equipment, environment
With the disinfection and hygiene of general body surface.
Composition stoste has efficient bioactivity, has height to Gram-negative and Gram-positive pathogenic bacterium and fungi
Effect, microbiological test show wide sterilization spectrum and the fast bioactivity feature of killing rate, 1 minute realizations quick sterilization, to user
Shortcut function service is provided, this effect is considerably beyond similar product；Liquid product can be prepared into spray, aerosol, cream
Agent, true solution system show the actual effect used, convenience and high-efficiency and economic advantages of the invention.
All material uses the raw material of most safety and environmental protection, evil non-toxic to humans and stimulation, capable of being fast degraded in nature, belongs to
In environmentally friendly product, can be directly applied to family, hospital's air-conditioning, food manufacturing apparatus surface, furniture disinfection and
Clean safety and sanitation rank, general disinfectant can not accomplish that effect is also incomparable.
The innovative design intersected using the high quaternary ammonium cation chemical combination object of most advanced environmental safety and biguanide compound,
The respective bioactivity deficiency of the two is compensated for, test result produces powerful synergy, enhances bioactivity, thus
The characteristics of foring wide sterilization spectrum, and have efficiently to fungi, this is the disinfectant of the present invention with other single bactericidal active constituents
Compared to the advantage with technology.Simultaneously by intersecting the preparation system of compatibility, test result has been confirmed to corrosion inhibition for metal ability
Reinforce, shows the very low final effect of the rate of corrosion after preparation impregnates various metals sample.Preferred surfactant and rouge
Fat alcohol active component design with quaternary ammonium salt cationic and guanidine active component, form complement each other, synergistic sterilization
The overall effect that the multiple activities of cleaning and anti-corrosion of metal combine, forms the preparation system of innovation.
Furthermore system of the present invention can remove clothing electrostatic, and soft dress material does not have oxidative decoloration denaturation to dress material；It is right
Metal protection is atomic, non-stimulated to application on human skin, can not only machine-wash but also can hand-wash it is how both effectiveness, but also because this disinfectant can
With kill cause a disease it is white read fungi, effectively remove pathogen transmission medium, not will cause cross-infection, use process is than other similar productions
Product more secure and reliable.
The active constituent of invention formulation sterilization stability in this preparation system is good, and the shelf-life 24~36 months or more,
It is non-degradable, not easy to change, technology of the reliable and stable characteristic for being conducive to long-term preservation and transport also superior to other similar products.
It should be noted that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to preferable
Embodiment describes the invention in detail, those skilled in the art should understand that, it can be to technology of the invention
Scheme is modified or replaced equivalently, and without departing from the spirit and scope of the technical solution of the present invention, should all be covered in this hair
In bright scope of the claims.
Claims (8)
1. it is a kind of for air-conditioning and general object hard surface disinfection and hygiene preparation, it is characterised in that: including quaternary ammonium salt
Cationic compound, guanidine compound, intercalating agent, fatty alcohols, activating agent, water；
Wherein, in terms of mass fraction, 0.2~5 part of quaternary ammonium salt cationic compound, 0.01~2 part of guanidine compound, intercalating agent
0.1~1 part, 5~18 parts of fatty alcohols, 2~10 parts of activating agent, remainder are water；
The quaternary ammonium salt cationic compound includes: dimethyl double lauryl ammonium chlorides, dodecyl dimethyl ethylbenzene oxygen second
The double certain herbaceous plants with big flowers ammonium chlorides of base ammonium bromide, dimethyl, the double certain herbaceous plants with big flowers base ammonium bromides of dimethyl, the double certain herbaceous plants with big flowers base ammonium carbonates of dimethyl, diethyl double ten
Dialkyl group ammonium carbonate, dimethyl double tetradecyl ammonium chloride, dimethyl double hexadecyl ammonium chloride, benzethonium chloride, benzyl rope bromine ammoniums
One or more of.
2. existing as described in claim 1 for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene, feature
In: the guanidine compound includes: the derivative of the derivative of poly hexamethylene biguanide or its salt, polyhexamethylene list guanidine or its salt
It is one such or several.
3. as claimed in claim 1 or 2 for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene, feature
Be: the activating agent includes: alkyl glycosides, propyl betaine, empgen BB, fatty alcohol polyoxyethylene ether, oxidation
One or more of cocamidopropyl propyl amide amine, polyvinyl alcohol 400, polyvinyl alcohol 600.
4. as claimed in claim 1 or 2 for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene, feature
Be: the fatty alcohols include: ethyl alcohol, ethylene glycol, propyl alcohol, isopropanol, propylene glycol, glycerine, butanol, in 1,3-BDO
One or more.
5. as claimed in claim 1 or 2 for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene, feature
Be: the intercalating agent includes: ethylenediamine tetra-acetic acid, disodium ethylene diamine tetraacetate, tetrasodium ethylenediamine tetraacetate, ethylenediamine tetrem
One or more of sour potassium sodium, B,EDTA, five sodium of aminotrimethylene phosphoric acid.
6. as claimed in claim 1 or 2 for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene, feature
It is: further includes, pigment and/or essence；In terms of mass fraction, 0~1 part of pigment, 0~1 part of essence.
7. preparing the described in any item systems for being used for air-conditioning and the disinfection of general object hard surface and hygiene of claim 1~6
The method of agent, it is characterised in that: including,
Add water to reaction kettle；
Intercalating agent is added in reaction kettle under stirring, stirring heats up and controls at 30 DEG C~70 DEG C；
The bioactive agent composition is added；
The fatty alcohols is added, being sufficiently stirred is completely dispersed it uniformly；
It the guanidine compound is added is sufficiently stirred and make it completely dissolved；
The quaternary ammonium salt cationic compound is added to make it completely dissolved and be uniformly dispersed, flow back 10~20min；
Acidometer accurate measurements are used at 25 DEG C of solution temperature, and adjust the pH value of solution between 5.0~8.0；
Water is added, stirs evenly, flow back 10~20min.
8. the method for preparing the preparation as claimed in claim 7 for being used for air-conditioning and the disinfection of general object hard surface and hygiene,
It is characterized by also including be added essence and/or pigment.
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| CN201910130947.7A CN109777639B (en) | 2019-02-22 | 2019-02-22 | Preparation for disinfecting and cleaning hard surface of air conditioner and general objects and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111073772A (en) * | 2019-12-17 | 2020-04-28 | 河南绿澳化工科技有限公司 | Air conditioner cleaning agent and preparation method thereof |
| CN111493073A (en) * | 2020-05-28 | 2020-08-07 | 李学军 | Surface disinfection film covering agent and preparation method thereof |
| CN111642512A (en) * | 2020-03-12 | 2020-09-11 | 天天向上(宁波)医疗科技有限公司 | High-efficiency disinfectant and preparation method and use method thereof |
| CN111771886A (en) * | 2020-08-20 | 2020-10-16 | 开平市美康泉生物科技有限公司 | Double-long-chain compound quaternary ammonium salt disinfectant for indoor and air-conditioning ventilation systems |
| CN113136040A (en) * | 2021-05-08 | 2021-07-20 | 中国科学院华南植物园 | Cationic starch gel and preparation method and application thereof |
| CN114246180A (en) * | 2020-09-24 | 2022-03-29 | 湖南五指峰生化有限公司 | Foam cleaning disinfectant and preparation method thereof |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6762162B1 (en) * | 2003-06-18 | 2004-07-13 | S. C. Johnson & Son, Inc. | Disinfecting cationic polymer cleaner comprising an acrylate cationic polymer |
| WO2006005108A1 (en) * | 2004-07-09 | 2006-01-19 | Nanosonics Pty Limited | Method and composition for high level disinfection employing quaternary ammonium compounds |
| CN101812383A (en) * | 2010-05-20 | 2010-08-25 | 北京绿伞化学股份有限公司 | Disinfecting detergent and preparation method thereof |
| CN101926353A (en) * | 2010-07-07 | 2010-12-29 | 高旭 | Disinfectant in field of food and preparation method |
| CN101933512A (en) * | 2010-07-05 | 2011-01-05 | 高旭 | Disinfectant capable of being used with high dilution multiples, preparation method and application |
| CN102015986A (en) * | 2008-03-16 | 2011-04-13 | 阿尔托斯医疗有限公司 | Cleaning, sanitising and sterilising preparations |
| CN102302033A (en) * | 2011-07-12 | 2012-01-04 | 覃终 | Preparation and application of compounded disinfection atomization agent |
| CN103013687A (en) * | 2012-12-24 | 2013-04-03 | 中国船舶重工集团公司第七一八研究所 | Foam cleaning disinfectant and preparation method thereof |
| CN109169653A (en) * | 2018-10-24 | 2019-01-11 | 湖北荷普药业股份有限公司 | A kind of cation composite disinfectant and its application |
-
2019
- 2019-02-22 CN CN201910130947.7A patent/CN109777639B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6762162B1 (en) * | 2003-06-18 | 2004-07-13 | S. C. Johnson & Son, Inc. | Disinfecting cationic polymer cleaner comprising an acrylate cationic polymer |
| WO2006005108A1 (en) * | 2004-07-09 | 2006-01-19 | Nanosonics Pty Limited | Method and composition for high level disinfection employing quaternary ammonium compounds |
| CN102015986A (en) * | 2008-03-16 | 2011-04-13 | 阿尔托斯医疗有限公司 | Cleaning, sanitising and sterilising preparations |
| CN101812383A (en) * | 2010-05-20 | 2010-08-25 | 北京绿伞化学股份有限公司 | Disinfecting detergent and preparation method thereof |
| CN101933512A (en) * | 2010-07-05 | 2011-01-05 | 高旭 | Disinfectant capable of being used with high dilution multiples, preparation method and application |
| CN101926353A (en) * | 2010-07-07 | 2010-12-29 | 高旭 | Disinfectant in field of food and preparation method |
| CN102302033A (en) * | 2011-07-12 | 2012-01-04 | 覃终 | Preparation and application of compounded disinfection atomization agent |
| CN103013687A (en) * | 2012-12-24 | 2013-04-03 | 中国船舶重工集团公司第七一八研究所 | Foam cleaning disinfectant and preparation method thereof |
| CN109169653A (en) * | 2018-10-24 | 2019-01-11 | 湖北荷普药业股份有限公司 | A kind of cation composite disinfectant and its application |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111073772A (en) * | 2019-12-17 | 2020-04-28 | 河南绿澳化工科技有限公司 | Air conditioner cleaning agent and preparation method thereof |
| CN111642512A (en) * | 2020-03-12 | 2020-09-11 | 天天向上(宁波)医疗科技有限公司 | High-efficiency disinfectant and preparation method and use method thereof |
| CN111493073A (en) * | 2020-05-28 | 2020-08-07 | 李学军 | Surface disinfection film covering agent and preparation method thereof |
| CN111771886A (en) * | 2020-08-20 | 2020-10-16 | 开平市美康泉生物科技有限公司 | Double-long-chain compound quaternary ammonium salt disinfectant for indoor and air-conditioning ventilation systems |
| CN114246180A (en) * | 2020-09-24 | 2022-03-29 | 湖南五指峰生化有限公司 | Foam cleaning disinfectant and preparation method thereof |
| CN113136040A (en) * | 2021-05-08 | 2021-07-20 | 中国科学院华南植物园 | Cationic starch gel and preparation method and application thereof |
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