CN101926353A - Disinfectant in field of food and preparation method - Google Patents
Disinfectant in field of food and preparation method Download PDFInfo
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- CN101926353A CN101926353A CN2010102194963A CN201010219496A CN101926353A CN 101926353 A CN101926353 A CN 101926353A CN 2010102194963 A CN2010102194963 A CN 2010102194963A CN 201010219496 A CN201010219496 A CN 201010219496A CN 101926353 A CN101926353 A CN 101926353A
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Abstract
The invention provides a disinfectant in the field of food and a preparation method. The disinfectant is endowed with high bactericidal bioactivity through the superiority complementation of cationic active matters guanidines and long-chain quaternary ammonium salts which have different structures and properties and the cross composite design of fatty alcohol, an active agent and a chelant, simultaneously has the advantages of high stability, safety and environmental protection and is mainly applied to the disinfection and cleaning of the surfaces of fruits, vegetables and common objects in food processing, food equipment, environment and family life.
Description
Technical field
The present invention relates at food processing industry as dairy industry, beer, beverage environment and equipment, fruit and vegetable, the furniture disinfecting cleaning treatment technology of body surface and individual family, the scientific quantitative analysis combination of the safe environment protection type sterilization component that main employing is newer in the world and other auxiliary element, produce sterilization biologically active efficiently, use high multiple dilution back, material and preparation environmental friendliness, have safe and reliable bactericidal effect and hygiene characteristics at good stability.
Background technology
Along with the fast development of food processing industry and the raising day by day of living standards of the people, antiseptic hygiene work is also universal day by day, and various requirement and standard are also in continuous improve.Sell current domestic and international market and the foodstuff disinfectant of use mainly is 84 class disinfectants, its main component is the clorox active matter, the problem of this disinfectant maximum is a poor stability, shelf life of products 3-12 month, to Food Oxidation decolouring sex change, excitant is arranged and in environment or food, chemical reaction takes place to the metal heavy corrosion with to human skin, produce organochlorine such as chloroform and confirmed it is the inducement that causes tumour by medical experiment, development in future trend is that 84 disinfectants that contain the clorox class are finally withdrawn from the market certainly; The peroxide disinfectant, the bactericidal activity height, but maximum problem is a poor stability, the people is stimulated by force, to the metal protection height; Quaternary ammonium salt such as chlorhexidine acetate, the safety of gluconic acid Chlorhexidine are good, but solvability is little in the water, biologically active is poor, it is low effect disinfectants, when especially dilution is used, can not satisfy the needs of disinfecting, therefore develop a kind of safety and environmental protection sterilization combination, good water solubility, the disinfectant that still has higher bactericidal activity under the diluting condition is the needs of era development.
Summary of the invention
A main purpose of the present invention provides disinfectant in field of food and preparation method
For achieving the above object, the present invention adopts following design:
Disinfectant in field of food and preparation method
Adopt liquid formulation, this thimerosal comprises following composition and weight portion proportioning: guanidine compound 0-10 part; Surfactant 0-8 part; Quaternary ammonium salt cationic compound 2-10 part; Intercalating agent 0-1 part; Aliphatic alcohols 0-10 part; Deionized water 30-90 part.The state of this disinfectant is colourless or light yellow transparent liquid, and pH value of solution is at 5.5-7.5.After preparation is finished, can use (disinfectant stock solution: water), after the dilution proportion according to (1: 50)-(1: 300), be applied to the sterilization and the cleaning of food processing equipment, packaging material, gourd, fruit and vegetable surface and general body surface.
Guanidine class chemical combination comprises among the present invention: guanidine hydrochloride, guanidine carbonate, phosphoguanidine, poly (hexamethylene) hydrochloride, hexamethylene, poly hexamethylene biguanide phosphate, poly hexamethylene biguanide carbonate.
Surfactant comprises: one or more in polyvinyl alcohol 400, polyvinyl alcohol 600, alkyl glycoside (alkyl carbon number 8-10), CAB, empgen BB, fatty alcohol-polyoxyethylene ether (AEO3), fatty alcohol-polyoxyethylene ether (AEO9), polysorbas20, polysorbate60, the Tween 80, and as active auxiliary element.
The quaternary ammonium salt cationic compound comprises: the two dodecyl chlorination ammoniums of benzalkonium bromide, benzalkonium chloride, dimethyl, dimethyl double hexadecyl ammonium chloride, dodecyl dimethyl ethylbenzene oxygen ethyl ammonium bromide, the two certain herbaceous plants with big flowers ammonium chlorides of dimethyl, the two certain herbaceous plants with big flowers base of dimethyl ammonium bromide, the two certain herbaceous plants with big flowers base of dimethyl ammonium carbonate, the two tetradecyl ammonium chlorides of dimethyl,, in the benzethonium chloride one or more, as fungicide active ingredient.
Aliphatic alcohols comprises: ethanol, propyl alcohol, isopropyl alcohol, propane diols, glycerine, butanols, 1, one or more in the 3-butanediol are as solvent and synergist.
Intercalating agent comprises: one or more in ethylenediamine tetra-acetic acid, disodium ethylene diamine tetraacetate, tetrasodium ethylenediamine tetraacetate, ethylenediamine tetra-acetic acid potassium sodium, B,EDTA, amino trimethylene methyl acid phosphate five sodium, and as the synergy auxiliary material.
Preparation main method of the present invention and step are as follows:
1, earlier by after the weighing of 30-90 part deionized water it being joined reactor.
2, stirring joins the intercalating agent of 0-1 part in the reactor down, and stirring heats up also is controlled at 30 ℃-70 ℃.
3, the bioactive agent composition that adds metering 0-8 part while stirring.
4, the 0-10 part aliphatic alcohols that adds metering while stirring, fully stirring is uniformly dispersed it fully.
5 add the biguanide compound of metering while stirring.
5,3-10 part quaternary ammonium salt cationic compound of the accurate metering of adding while stirring dissolves it fully and is uniformly dispersed.
6, backflow 10-20min.
7, when 25 ℃ of solution temperatures, adopt acidometer accurately to monitor, and the pH value of regulator solution is between 5.5-7.5.
8, final products are colourless or light yellow transparent liquid.
Embodiment
Each component in the following embodiment of the invention all is weight portions
Embodiment 1
2 parts of fatty alcohol-polyoxyethylene ether (AEO9)
0.05 part of disodium ethylene diamine tetraacetate
6 parts of propane diols
2 parts of hexamethylene
5 parts of the two certain herbaceous plants with big flowers ammonium chlorides of dimethyl
85 parts of deionized waters
Take by weighing 85 parts of deionized waters, be injected in the reactor, under agitation, add 0.05 part of disodium ethylene diamine tetraacetate, temperature control is at 30 ℃-60 ℃, after dissolving is finished, add fatty alcohol-polyoxyethylene ether (AEO9) 2 parts, add 6 parts of propane diols, add 5 parts of the two certain herbaceous plants with big flowers ammonium chlorides of dimethyl, refluxed 20 minutes, and when 25 ℃ of solution temperatures, adopt acidometer accurately to monitor, and the pH value of regulator solution was between 5.0-7.5.Backflow 10-20 minute, obtain the colourless liquid product of clear.Water carries out operational processes as 50 times, 100 times, 300 times to sterilization objects according to different dilution proportion according to different application targets.
Embodiment 2
Take by weighing 80 parts of deionized waters, be injected in the reactor, under agitation, add 0.3 part of tetrasodium ethylenediamine tetraacetate, temperature control after dissolving is finished, adds 3 parts of CAB at 35 ℃-50 ℃, add 5 parts of glycerine, 3 parts of poly (hexamethylene) hydrochlorides add 5 parts of dodecyl dimethyl ammonium chlorides, reflux 20 minutes, when 25 ℃ of solution temperatures, adopt acidometer accurately to monitor, and the pH value of regulator solution is between 5.0-7.5.Backflow 10-20 minute, obtain the colourless liquid product of clear.
Embodiment 3
6 parts of the two certain herbaceous plants with big flowers ammonium chlorides of dimethyl
0.1 part of disodium ethylene diamine tetraacetate
6 parts of propane diols
3 parts of fatty alcohol-polyoxyethylene ether (AEO9)
3 parts of hexamethylene
82 parts of deionized waters
Take by weighing 82 parts of deionized waters, be injected in the reactor, under agitation, add 0.1 part of disodium ethylene diamine tetraacetate, temperature control after dissolving is finished, adds fatty alcohol-polyoxyethylene ether (AEO9) 3 parts at 30 ℃-40 ℃, add 6 parts of propane diols, 3 parts of hexamethylene add 6 parts of the two certain herbaceous plants with big flowers ammonium chlorides of dimethyl, reflux 20 minutes, when 25 ℃ of solution temperatures, adopt acidometer accurately to monitor, and the pH value of regulator solution is between 5.5-7.5.Backflow 10-20 minute, obtain the colourless liquid product of clear.The said goods is used with deionized water or running water dilution back again, (disinfectant stock solution: water), after the dilution proportion according to (1: 50), (1: 100), (1: 300), as the sterilization and the cleaning of food, gourd, fruit and vegetable and general body surface.
This disinfectant of table 1 is to cucumber surface disinfection simulated field experimental result
Experimental strain: Escherichia coli 8099 Military Medical Science Institutes-the 11st generations
2002 editions 2.1.2.9 of test basis " Ministry of Public Health's disinfection technology standard ", assay proves: 100 times of dilutions of disinfectant of the present invention, effect 10min kills logarithm＞3.00 to surface each time of the Escherichia coli test of the fresh cucumber of artificial contamination.
100 times of dilution acute oral toxicity tests of table 2 disinfectant of the present invention result
According to " Ministry of Public Health's disinfection technology standard " 2002 editions 2.3.1 acute oral toxicity tests, the disinfectant male and female chmice acute per os median lethal dose value of the present invention＞5000mg/kg b.wt that tries belongs to actual nontoxic level.
Require suggestion and U.S. FDA, the login of EPA compound according to ministry of Health of China about the catalogue that can be used safely in food service industry disinfectant raw material, the used all material of disinfectant of the present invention belongs to the row of catalogue, reaching this requires the product could be in the food production sector application, simultaneously, verified design philosophy of the present invention and target according to tests such as above large number of biological, Disinfection, physics, toxicitys: under the dilute with water condition, can effectively be applied to the food production environment,, the sterilization and the hygiene of food processing equipment surface and vegetable and fruit etc.
Summary of the present invention:
1, adopt the raw material of safety and environmental protection, capable of being fast degraded at nature to human nonhazardous and stimulation, belong to environmentally friendly product, can reach the sterilization that is applied in food production equipment and the safety and sanitation rank of cleaning, general disinfectant can't be accomplished.
2, active component adopts the innovative design of dicationic compounds, both sterilization biologically active deficiencies have separately been remedied, formed again simultaneously more powerful synergy, strengthened biologically active, thereby having formed the wide characteristics of fungicidal spectrum, this is that the present invention compares the advantage that possesses skills with the disinfectant of other single bactericidal active constituent. The modular design of preferred surfactant and fatty alcohol and cation activity combination have formed the whole innovation system of complementary sterilizing cleaning.
3, the active component of sterilization good stability in this preparation system, more than shelf-life 24-36 month, active component is not degraded, and is not easy to change, and reliable and stable characteristic also is better than other like product.
Claims (7)
1. disinfectant in field of food and preparation method is characterized in that it contains following component in weight portion: guanidine compound 0-10 part; Surfactant 0-8 part; Quaternary ammonium salt cationic compound 2-10 part; Intercalating agent 0-1 part; Aliphatic alcohols 0-10 part; Deionized water 30-90 part.The state of this disinfectant is colourless or light yellow transparent liquid, and pH value of solution is at 5.5-7.5.
2. it is characterized in that according to the described disinfectant in field of food of claim that described guanidine class chemical combination is guanidine hydrochloride, guanidine carbonate, phosphoguanidine, poly (hexamethylene) hydrochloride, hexamethylene, poly hexamethylene biguanide phosphate, poly hexamethylene biguanide carbonate.
3. it is characterized in that according to the described disinfectant in field of food of claim that described surfactant is one or more in polyvinyl alcohol 400, polyvinyl alcohol 600, alkyl glycoside (alkyl carbon number 8-10), CAB, empgen BB, fatty alcohol-polyoxyethylene ether (AEO3), fatty alcohol-polyoxyethylene ether (AEO9), polysorbas20, polysorbate60, the Tween 80.
4. it is characterized in that according to the described disinfectant in field of food of claim, described quaternary ammonium salt cationic compound be the two dodecyl chlorination ammoniums of benzalkonium bromide, benzalkonium chloride, dimethyl, dimethyl double hexadecyl ammonium chloride, dodecyl dimethyl ethylbenzene oxygen ethyl ammonium bromide, the two certain herbaceous plants with big flowers ammonium chlorides of dimethyl, the two certain herbaceous plants with big flowers base of dimethyl ammonium bromide, the two certain herbaceous plants with big flowers base of dimethyl ammonium carbonate, the two tetradecyl ammonium chlorides of dimethyl,, in the benzethonium chloride one or more.
5. it is characterized in that according to the described disinfectant in field of food of claim 1 that described intercalating agent is one or more in ethylenediamine tetra-acetic acid, disodium ethylene diamine tetraacetate, tetrasodium ethylenediamine tetraacetate, ethylenediamine tetra-acetic acid potassium sodium, B,EDTA, amino trimethylene methyl acid phosphate five sodium.
6. according to the described disinfectant in field of food of claim 1, it is characterized in that described aliphatic alcohols is ethanol, propyl alcohol, isopropyl alcohol, propane diols, glycerine, butanols, 1, one or more in the 3-butanediol.
7. can dilute the disinfectant preparation method who uses by high multiple according to claim 1 is described, it is characterized in that this method comprises the steps:
Earlier by after the weighing of 30-90 part deionized water it being joined reactor; Intercalating agent with 0-1 part under stirring joins in the reactor, and stirring heats up also is controlled at 30 ℃-70 ℃; The bioactive agent composition that adds metering 0-8 part while stirring; The 0-10 part aliphatic alcohols that adds metering while stirring, fully stirring is uniformly dispersed it fully; The biguanide compound that adds metering while stirring; Adding while stirring accurately 3-10 part quaternary ammonium salt cationic compound of metering is dissolved it fully and is uniformly dispersed; Backflow 10-20min.When 25 ℃ of solution temperatures, adopt acidometer accurately to monitor, and the pH value of regulator solution is between 5.5-7.5.Final products are colourless or light yellow transparent liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2010102194963A CN101926353A (en) | 2010-07-07 | 2010-07-07 | Disinfectant in field of food and preparation method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102194963A CN101926353A (en) | 2010-07-07 | 2010-07-07 | Disinfectant in field of food and preparation method |
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| CN101926353A true CN101926353A (en) | 2010-12-29 |
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| CN2010102194963A Pending CN101926353A (en) | 2010-07-07 | 2010-07-07 | Disinfectant in field of food and preparation method |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103805371A (en) * | 2014-02-28 | 2014-05-21 | 中国水产科学研究院淡水渔业研究中心 | Scavenging agent for sludge on surfaces of aquatic plants in aquaculture pond |
| CN104521959A (en) * | 2014-12-23 | 2015-04-22 | 广东环凯微生物科技有限公司 | Novel disinfectant prepared from quaternary ammonium salt and alcohol |
| CN104604923A (en) * | 2014-12-31 | 2015-05-13 | 莫海仪 | Novel solid sterilizing and disinfecting material, and preparation and application thereof |
| CN106035361A (en) * | 2016-05-23 | 2016-10-26 | 中国人民武装警察部队总医院 | Compound quaternary ammonium salt disinfection solution, and preparation method and application thereof |
| CN106857659A (en) * | 2017-04-01 | 2017-06-20 | 江西凝盛生物科技有限公司 | A kind of thing table thimerosal of asepsis environment-protecting and preparation method thereof |
| CN109722352A (en) * | 2018-12-21 | 2019-05-07 | 中国农业大学 | Remove combined type cleaning agent, the method and system of biofilm |
| CN109777639A (en) * | 2019-02-22 | 2019-05-21 | 江苏今日卫生用品有限公司 | It is a kind of for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene and preparation method thereof |
| CN111418586A (en) * | 2020-04-10 | 2020-07-17 | 上海美浮特生物科技有限公司 | Fruit and vegetable disinfectant and preparation method thereof |
| CN113261559A (en) * | 2021-05-31 | 2021-08-17 | 山东消博士消毒科技股份有限公司 | Low-temperature quaternary ammonium salt disinfectant and preparation method thereof |
| CN113293063A (en) * | 2021-03-17 | 2021-08-24 | 陕西中医药大学 | Food pathogenic bacteria disinfection cleaning agent |
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| CN1785565A (en) * | 2005-11-09 | 2006-06-14 | 高丹 | Metal shaping method based on local constrained electrochemistry |
| CN101684435A (en) * | 2008-09-28 | 2010-03-31 | 福建恒安集团有限公司 | Sterilization hand washing solution |
| CN101731257A (en) * | 2008-11-24 | 2010-06-16 | 兰州益生化工有限公司 | Novel polyhexamethylene guanidine compound disinfectant and preparation method |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103805371A (en) * | 2014-02-28 | 2014-05-21 | 中国水产科学研究院淡水渔业研究中心 | Scavenging agent for sludge on surfaces of aquatic plants in aquaculture pond |
| CN104521959A (en) * | 2014-12-23 | 2015-04-22 | 广东环凯微生物科技有限公司 | Novel disinfectant prepared from quaternary ammonium salt and alcohol |
| CN104521959B (en) * | 2014-12-23 | 2016-09-28 | 广东环凯微生物科技有限公司 | A kind of disinfectant solution utilizing quaternary ammonium salt and alcohol to prepare |
| CN104604923A (en) * | 2014-12-31 | 2015-05-13 | 莫海仪 | Novel solid sterilizing and disinfecting material, and preparation and application thereof |
| CN106035361A (en) * | 2016-05-23 | 2016-10-26 | 中国人民武装警察部队总医院 | Compound quaternary ammonium salt disinfection solution, and preparation method and application thereof |
| CN106857659A (en) * | 2017-04-01 | 2017-06-20 | 江西凝盛生物科技有限公司 | A kind of thing table thimerosal of asepsis environment-protecting and preparation method thereof |
| CN109722352A (en) * | 2018-12-21 | 2019-05-07 | 中国农业大学 | Remove combined type cleaning agent, the method and system of biofilm |
| CN109777639A (en) * | 2019-02-22 | 2019-05-21 | 江苏今日卫生用品有限公司 | It is a kind of for air-conditioning and the disinfection of general object hard surface and the preparation of hygiene and preparation method thereof |
| CN109777639B (en) * | 2019-02-22 | 2021-11-16 | 江苏今日卫生用品有限公司 | Preparation for disinfecting and cleaning hard surface of air conditioner and general objects and preparation method thereof |
| CN111418586A (en) * | 2020-04-10 | 2020-07-17 | 上海美浮特生物科技有限公司 | Fruit and vegetable disinfectant and preparation method thereof |
| CN113293063A (en) * | 2021-03-17 | 2021-08-24 | 陕西中医药大学 | Food pathogenic bacteria disinfection cleaning agent |
| CN113261559A (en) * | 2021-05-31 | 2021-08-17 | 山东消博士消毒科技股份有限公司 | Low-temperature quaternary ammonium salt disinfectant and preparation method thereof |
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Application publication date: 20101229 |