CN109700880A - A kind of infantile cough's syrup and preparation method thereof - Google Patents
A kind of infantile cough's syrup and preparation method thereof Download PDFInfo
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Abstract
The present invention discloses a kind of infantile cough's syrup and preparation method, this formula composition and number are as follows: infantile cough's syrup is made in 1~2 part of eucalyptus leaf extract, 2~4 parts of houttuynia extract, 1~4 part of faint scent leaf extract, 2~5 parts of peppermint leaf extract, 0.1~0.2 part of benzoic acid, 30~50 parts of molasses, 5~10 parts of loquat-leaf extract.Infantile cough's syrup of the invention, various composition comprehensive function simultaneously, makes patient can be with Symptomatic medicine, with strong points, treatment time is short, significant in efficacy, infantile cough's syrup of the invention further enriches herbal species, and infantile cough's syrup preparation is convenient, cheap.
Description
Technical field
The present invention relates to a kind of cough syrup, in particular to a kind of infantile cough's syrup and preparation method.
Background technique
Infantile cough is a kind of defensive allocinesis, can prevent foreign-body aspiration, prevent the accumulation of bronchial secretion,
It removes secretion and avoids respiratory tract secondary infection.Any cause of disease causes respiratory tract Acute and chronic inflammation that can cause to cough.According to disease
Journey can be divided into acute cough, subacute cough and chronic cough: 1, acute cough: refer to that the course of disease less than 2 weeks, is more common in breathing
Road or lower respiratory tract infection cause and asthma in acute attack;2, subacute cough: refer to the course of disease be greater than 2 weeks and less than 4 weeks,
Bacterial sinusitis and asthma are found in addition to respiratory tract infection;3, chronic cough: cough symptom is lasting > it is known as chronic cough within 4 weeks
It coughs.
Wherein, infantile cough due to common cold is the cough as caused by exogenous disease ailment said due to cold or exposure, is affected by the cold by body, caused by Lung Qi obstraction
Cough, clinical visible cough is low voice speaking, and pharynx is itched, and aversion to cold is lossless, and urgency is very then breathed heavily in headache or fever.Treat infantile cough's at present
Cough syrup is very more, and existing cough syrup has palliative, and some leads to drug valence using expensive ingredient
Lattice are high, some manufacture craft very complicateds, and it is crucial that existing P-Cymene be generally used for treating it is various types of
Cough, and not individually in infantile cough due to common cold, curative effect is excessively broad, causes the ingredient of formula various in a jumble, to real
The specific aim of the cause of disease is low, and uncertain therapeutic efficacy is cut, slow effect, these P-Cymenes have slight infantile cough due to common cold certain
Curative effect, but when encountering the heavier situation of the state of an illness, its effect is just not obvious, and therapeutic effect is poor.
Therefore, Symptomatic medicine how is realized, with strong points, treatment time is short, and it is significant in efficacy, and prepare convenient, price
Infantile cough's syrup of cheap treatment infantile cough due to common cold is technical problem urgently to be resolved in the industry.
Eucalyptus leaf extract presses the leaf of (Eucalyptusglobulus Labill.) as raw material using myrtle indigo plant
It extracts, contains volatile oil, principal component is eucalyptol, australene, α-phellandrene etc. in oil.It is living with physiology such as antibacterial, eliminating the phlegm, decompressions
Property.Food, chemical industry, medicine, environment, in terms of have extensive purposes.Eucalyptus leaf extract can reduce animal blood pressure,
Antihypertensive effect is due to caused by release histamine, and decompression effective component may be a kind of tannin.Gallic acid is in vitro to grape
Coccus, pneumococcus, Escherichia coli, shigella dysenteriae etc. have obvious inhibiting effect, and infected by influenza also has certain inhibiting effect.Eucalyptus
Leaf oil in vitro can still kill Trichomonas vaginalis.The eucalyptus oil that Eucalyptus globulus Labill leaf proposes has certain treating tuberculosis effect, and sucking can be used for
Treat respiratory tract infection.Eucalyptus globulus Labill leaf preserved material and eucalyptus oil can be used as inhalant for breathe be illness, especially upper respiratory tract sense
Dye;There are a phlegm-dispelling functions after chronic bronchitis clothes, both oral administration or may be inhaled when asthma.Eucalyptus oil and Eucalyptus globulus Labill leaf preserved material are still used
In certain skin diseases, and as the surface of a wound, ulcer, fistula irrigation.Have after eucalyptus oil leaf is for oral administration and drive hookworm effect, tannic acid has gently
Convergence is spent, volatile oil has wind dispelling effect, and volatile oil is absorbed from alimentary canal, partially by respiratory excretion.In addition, eucalyptus oil
The still antalgesic as deodorant and neuralgia patient.
Cordate houttuynia (Houttuynia Cordata Thumb.) also known as heartleaf houttuynia, Cen grass, root of picking up the ears, smelly raw meat grass etc. are three
The herb of Bai Cao section heartleaf houttuynia platymiscium, is herbaceos perennial, because its cauline leaf rub with the hands it is broken after have a fish like smell, therefore named cordate houttuynia.Often
It is grown in the shade hillside, village side ridge, in riverside small stream side and wetland thick grass.Cordate houttuynia protein rich in, fatty carbon water
Compound, calcium, phosphorus, iron and VC, VP, VB1, VB6, VE and dietary fiber abundant, in addition, cordate houttuynia also has clearly
Leaching, detumescence row's gland and the effect for enhancing body's immunity are gushed in heat, removing toxic substances, anti-inflammatory, antibacterial, antiviral, diuresis.Cordate houttuynia quilt
Health ministry is formally determined as " being both food and drug ", it has also become the medicinal, health care of one kind and edible value are more
Edible resource.
Pistacia weinmannifolia (scientific name: Pistacia weinmannifoliaJ. Poisson ex Franch.) Anacardiaceae shrub or
Dungarunga;Ye Keti aromatic oil, civil common leaf grind powder system " perfume ".Leaf and bark hyoscine, have eliminating inflammation and expelling toxin, astringing to arrest diarrhea it
Effect.
Dried peppermint leaf is the leaf of plant peppermint, and taste is refrigerant, with luxuriant lotus leaf, jintan grass, rising Yang grass, Bu He title it is thin
Lotus, mainly compositions containing peppermint oil, menthol and menthones, isomenthone, Rosmarinic acid etc..It can be with stomach invigorating wind-dispelling, eliminating the phlegm, benefit
Gallbladder, anti-spasm improve sense Mao fever, throat, swelling and pain, and eliminate headache, toothache, nausea sense.
Loguat leaf (scientific name: Eriobotrya japonica Thunb.) is the leaf of rosaceous plant loquat.Containing volatilization
Oil, main component are that nerolidol (Nerolidol) and fanesol (Farnesol) still has α and beta pinene, amphene, laurel
Alkene, to P-cymene, linalool, ylangene, α and β farnesene, camphor, nerol, Geraniol, α-pilgerol,
Elemol, cis- β, γ-hexenol and linalool oxide also contain amygdalin (Amygdalin), ursolic acid, oleanolic acid,
The such as tartaric acid, citric acid, malic acid, tannin, vitamin B and vitamin C also contain D-sorbite (Sorbitol).There is clearing lung-heat to stop
Cough, stomach function regulating diuresis, the effect of quenching the thirst.
Molasses are the byproducts of sugar industry, are sticky one kind, dark brown, in semifluid object, group origin cause of formation sugaring is former
Material, processing conditions it is different and variant, sucrose and reduced sugar account for 30%~50%, with the sugar materials such as sugarcane and beet sugaring about produce
Molasses more than 3% sugar material out.Molasses yield is biggish beet molasses, cane molasses, a grape molasses, and yield is lesser to be had and turn
Change molasses and refinery molasses.It is mainly used as the substrate or base-material of the fermented products such as yeast, monosodium glutamate, organic acid.It also is used as certain
The raw material and animal feed of food.The main component of molasses is carbohydrate, and cane molasses about 24%-36% containing sucrose, other sugar are about
12%-24%;Carbohydrate contained by beet molasses is almost all sucrose, about as many as 47%.Furthermore also containing 3%-4%'s in nitrogen-free extracts
Soluble colloid, predominantly xylane, araban and pectin etc..The content of mineral substances of molasses is higher, about 8%-10%, but
Calcium, phosphorus content be not high, and cane molasses are higher than beet molasses again.Potassium, chlorine, sodium, content of magnesium are high in mineral element, therefore molasses have
Laxative qualits.General molasses vitamin content is low, but pantothenic acid content is higher in cane molasses, reaches 37mg/kg.Molasses can be used to pre-
Cough caused by anti-, treatment and improvement cough symptom, especially inflammation of upper respiratory tract.
A kind of aqueous Chinese medicine plaster for external application for treating infantile cough is disclosed in patent CN105125984B, can effectively be solved
The problem of traditional patch drugloading rate is low, the continuous action time is short, allergy easy to children, the technical solution solved is, by following
The material medicine of poidometer is made: bulbus fritillariae cirrhosae 30-40g, tuber of stemona 30-40g, campanulaceae 30-40g, RADIX PEUCEDANI 20-30g, the tuber of pinellia
20-30g, honeysuckle 20-30g, calculus bovis factitius 0.6-0.8g and borneol 0.5-0.8g, compatibility of the present invention is reasonable, curative for effect, with
Child skin compatibility is good, and no allergic phenomena, drugloading rate is big, and water content is high, is conducive to drug percutaneous skin Transdermal absorption, makes work
Skill is simple and easy, and materials are environmentally protective, is the innovation on the Traditional Chinese medicine plaster for treat infantile cough.
A kind of Chinese medicine for treating cough is disclosed in patent CN103301334B.Chinese medicine proportion is as follows: with bitter citrus immature flower 1-2
Part, 4-6 parts of lip vanilla, 1 part of decumbent corydalis tuber, 3-6 parts of duck gizzard-membrane, 3-5 parts of japanese cryptotaenia root, 4-6 parts of suona horn flower, 7-9 parts of wild chervil, high eyebrow
1-3 parts of rose, 5-7 parts of dawrf mallow root, 2-4 parts of sorghum rice bran, 2-4 parts of Radix Glycyrrhizae, 3-5 parts of almond, 8-10 parts of radix bupleuri, radish
5-7 parts sub-, 15-30 parts of Chinese yam, 10-12 parts of Poria cocos, 2-4 parts of cortex cinnamomi, 3-5 parts of Cortex Magnoliae Officinalis, 9-11 parts of loguat leaf, 4-6 parts of schizonepeta, tangerine
5-7 parts of stalk.Chinese Herbs of the invention are significant, securely and reliably, take simply, have good therapeutic effect to cough.
In patent CN102813803B, a kind of Chinese medicine using arisaema cum bile treatment infantile cough, each raw material group are disclosed
Point weight proportion are as follows: the weight proportion of its each raw material component are as follows: Snakegourd Fruit frost 13-17, lily 1-5, almond 8-12, Radix Polygalae 4-8,
Perillaseed 8-12, mustard seed 4-8, tendril-leaved fritillary bulb 13-17, scaly holly root 1-5, lepidium seed 8-12, vegetable seeds 4-8, mouse-ear 8-12, gekko 4-8, gallbladder
Southern Star 4-8, mandarin orange 13-17, desmodium triquetrum 1-5.The arisaema cum bile that the present invention reuses has effects that clearing away fire and eliminating phlegm, removing heat from lung and relieving asthma, right
Have in treatment infantile cough and help well, Chinese medicine of the present invention has the advantages that control symptom is rapid, curative for effect, nontoxic pair
Effect.
In patent CN101036719B, disclose a kind of syrup and preparation method thereof for treating infantile cough, it be by
Liquid extract of liquorice 50-400ml, Platycodon glaucus fluidextract 10-60ml, ammonium chloride 2-20g, orange peel tincture 10-40ml and sucrose 200-500g,
Made of sodium benzoate 3-7g.
Above-mentioned patent is to prepare a kind of Chinese medicine for treating infantile cough or syrup lotion with Chinese medicine compounding, generally existing small
Youngster's palatability is poor, be not easy to take, oxidation preventive content is higher, higher cost, is formulated that more complex and synergy is general to be lacked
Point.
Summary of the invention
The main object of the present invention is to provide a kind of infantile cough's syrup, it is intended to realize one kind can with Symptomatic medicine, be directed to
Property it is strong, quick, cooperate with, be curative for effect and significant, preparation is convenient, children's cough of cheap treatment infantile cough due to common cold
It coughs syrup.
A kind of infantile cough's syrup of the present invention and preparation method thereof, the formula composition of infantile cough's syrup and part
Number are as follows: 1~2 part of eucalyptus leaf extract, 2~4 parts of houttuynia extract, 1~4 part of faint scent leaf extract, peppermint leaf extract 2
~5 parts, 0.1~0.2 part of benzoic acid, 30~50 parts of molasses, 5~10 parts of loquat-leaf extract.
A kind of preparation method of infantile cough's syrup of the present invention, includes the following steps:
(1) first eucalyptus leaf extract, houttuynia extract, faint scent leaf extract, peppermint leaf extract and loguat leaf are extracted
It stirs evenly, is placed in 5~10 DEG C of freezer spare after being filtered after refrigerating 24~48h after object mixing;
(2) lead to 105~120 DEG C of sterilizings of steam after heating molasses in high-pressure sterilizing pot, keep the temperature 0.5~1.5h, heat preservation terminates
It is refiltered after 0~3 DEG C of 10~20min of standing of ice bath rear spare;
(3) by above-mentioned steps 1) mixture be added step 2 molasses in, after 2000~5000r/min homogeneous, 5~10min to
With;
(4) by above-mentioned steps 3) 200~500r/min of mixed liquor stir and be slowly added into benzoic acid mix after can be prepared into one
Kind infantile cough's syrup.
Heretofore described eucalyptus leaf extract is extracted with following methods:
(1) investment Universalpulverizer is crushed to 30~50 mesh after cleaning eucalyptus leaves;
(2) crushed material is placed in extractor, the water of 15~30 times of crushed material quality is added, adjusting and extracting pressure tank is 0.1
~0.2MPa, temperature are 65~75 DEG C, after extracting 1h~2h, stand 12h;
(3) by above-mentioned steps 2) extracting solution obtains filtered fluid by 120~160 mesh filter screens in extractor;
(4) the 1/3~1/4 of volume is concentrated the filtrate to, can be obtained eucalyptus leaf extract.
Heretofore described houttuynia extract, faint scent leaf extract, peppermint leaf extract and loquat-leaf extract
With the extracting method of eucalyptus leaf extract.
Heretofore described eucalyptus leaves are the eucalyptus leaves extracted after essential oil.
The function that heretofore described eucalyptus leaf extract has expelling wind to resolve the exterior, clearing heat and detoxicating, phlegm-eliminiating and qi-regulating, desinsection antipruritic
Effect.
Heretofore described molasses are one of beet molasses, cane molasses, grape molasses or mixture.
Heretofore described molasses are obtained with following methods:
(1) a certain amount of molasses are taken, brix is 20~30 ° of Bx, 10~20 times of water of addition stir after being heated to 70~80 DEG C after diluting
Mix 5~15min;
(2) supernatant is taken to can be obtained the present invention after 3000~5000r/min is centrifuged 5~15min in molasses after above-mentioned dilution
The molasses.
Heretofore described molasses contain amino acid, glycoconjugate, pigment, pectin, minerals etc., and compounding prepares syrup tool
There is the characteristics of palatability is good, do not precipitate, trophism.
Infantile cough's syrup of the invention, has the advantage that
(1) eucalyptus leaf extract, houttuynia extract, faint scent leaf extract and peppermint leaf extract all have eliminating inflammation and expelling toxin,
The effect of astringing to arrest diarrhea;Loquat-leaf extract has the effect of antiviral activity, antibacterial, clearing lung and relieving cough, stomach function regulating diuresis, it can be achieved that more
Kind effective ingredient coordination with the synthesis effect;
(2) molasses contain multiple components, and compounding, which prepares syrup, has the characteristics that palatability is good, does not precipitate, trophism;
(3) molasses can be used to cough caused by preventing, treating and improving cough symptom, especially inflammation of upper respiratory tract in the present invention
It coughs.
(4) raw material is all from natural plant raw material in the present invention, without any toxicity and side effects, highly-safe;
(5) present invention efficiently uses a variety of wastes, such as molasses, eucalyptus leaves, loguat leaf, realizes waste high value added utilization;
(6) because eucalyptus leaf extract and faint scent leaf extract have bactericidal bacteriostasis, therefore antioxidant uses in the present invention
It measures few compared with similar product;
(7) raw material is easy to get and utilizes part waste resource in the present invention, and cost is cheap compared with similar product.
Specific embodiment
It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not intended to limit the present invention.
Embodiment 1
A kind of infantile cough's syrup described in the present embodiment and preparation method thereof, the formula composition and number of infantile cough's syrup
Are as follows: 1 part of eucalyptus leaf extract, 2 parts of houttuynia extract, 1 part of faint scent leaf extract, 2 parts of peppermint leaf extract, benzoic acid
0.1 part, 30 parts, 5 parts of loquat-leaf extract of molasses (beet molasses, cane molasses, grape molasses, mass ratio 1:1:1).
A kind of preparation method of infantile cough's syrup, includes the following steps: described in the present embodiment
(1) first eucalyptus leaf extract, houttuynia extract, faint scent leaf extract, peppermint leaf extract and loguat leaf are extracted
It stirs evenly, is placed in 5 DEG C of freezer spare after refrigerating for 24 hours filtering afterwards after object mixing;
(2) lead to 105 DEG C of sterilizings of steam after heating molasses in high-pressure sterilizing pot, keep the temperature 1.5h, heat preservation terminates 0 DEG C of ice bath standing
It is refiltered after 10min rear spare;
(3) by above-mentioned steps 1) mixture is added in step 2 molasses, and it is stand-by after 2000r/min homogeneous 10min;
(4) by above-mentioned steps 3) mixed liquor 200r/min stir and be slowly added into benzoic acid mix after can be prepared into a kind of children
Cough syrup.
Embodiment 2
A kind of infantile cough's syrup described in the present embodiment and preparation method thereof, the formula composition and number of infantile cough's syrup
Are as follows: 2 parts of eucalyptus leaf extract, 4 parts of houttuynia extract, 4 parts of faint scent leaf extract, 5 parts of peppermint leaf extract, benzoic acid
0.2 part, 50 parts of molasses (beet molasses), 10 parts of loquat-leaf extract.
A kind of preparation method of infantile cough's syrup, includes the following steps: described in the present embodiment
(1) first eucalyptus leaf extract, houttuynia extract, faint scent leaf extract, peppermint leaf extract and loguat leaf are extracted
It stirs evenly, is placed in 10 DEG C of freezer spare after being filtered after refrigerating 48h after object mixing;
(2) lead to 120 DEG C of sterilizings of steam after heating molasses in high-pressure sterilizing pot, keep the temperature 0.5h, heat preservation terminates 3 DEG C of ice bath standings
It is refiltered after 20min rear spare;
(3) by above-mentioned steps 1) mixture is added in step 2 molasses, and it is stand-by after 5000r/min homogeneous 5min;
(4) by above-mentioned steps 3) mixed liquor 500r/min stir and be slowly added into benzoic acid mix after can be prepared into a kind of children
Cough syrup.
Embodiment 3
A kind of infantile cough's syrup described in the present embodiment and preparation method thereof, the formula composition and number of infantile cough's syrup
Are as follows: 1.5 parts of eucalyptus leaf extract, 3 parts of houttuynia extract, 3 parts of faint scent leaf extract, 3 parts of peppermint leaf extract, benzoic acid
0.13 part, 40 parts of molasses (cane molasses), 8 parts of loquat-leaf extract.
A kind of preparation method of infantile cough's syrup, includes the following steps: described in the present embodiment
(1) first eucalyptus leaf extract, houttuynia extract, faint scent leaf extract, peppermint leaf extract and loguat leaf are extracted
It stirs evenly, is placed in 8 DEG C of freezer spare after being filtered after refrigerating 36h after object mixing;
(2) lead to 110 DEG C of sterilizings of steam after heating molasses in high-pressure sterilizing pot, keep the temperature 1.0h, heat preservation terminates 2 DEG C of ice bath standings
It is refiltered after 15min rear spare;
(3) by above-mentioned steps 1) mixture is added in step 2 molasses, and it is stand-by after 3000r/min homogeneous 8min;
(4) by above-mentioned steps 3) mixed liquor 350r/min stir and be slowly added into benzoic acid mix after can be prepared into a kind of children
Cough syrup.
Embodiment 4
A kind of infantile cough's syrup described in the present embodiment and preparation method thereof, the formula composition and number of infantile cough's syrup
Are as follows: 2 parts of eucalyptus leaf extract, 3 parts of houttuynia extract, 1 part of faint scent leaf extract, 4 parts of peppermint leaf extract, benzoic acid
0.2 part, 45 parts, 6 parts of loquat-leaf extract of molasses (beet molasses, cane molasses, mass ratio 1:2).
A kind of preparation method of infantile cough's syrup, includes the following steps: described in the present embodiment
(1) first eucalyptus leaf extract, houttuynia extract, faint scent leaf extract, peppermint leaf extract and loguat leaf are extracted
It stirs evenly, is placed in 6 DEG C of freezer spare after being filtered after refrigerating 25h after object mixing;
(2) lead to 105 DEG C of sterilizings of steam after heating molasses in high-pressure sterilizing pot, keep the temperature 0.5h, heat preservation terminates 1 DEG C of ice bath standing
It is refiltered after 10min rear spare;
(3) by above-mentioned steps 1) mixture is added in step 2 molasses, and it is stand-by after 4000r/min homogeneous 5min;
(4) by above-mentioned steps 3) mixed liquor 400r/min stir and be slowly added into benzoic acid mix after can be prepared into a kind of children
Cough syrup.
Eucalyptus leaf extract described in foregoing invention Examples 1 to 4 is extracted with following methods:
(1) investment Universalpulverizer is crushed to 30 mesh after cleaning eucalyptus leaves;
(2) crushed material is placed in extractor, is added the water of 15 times of crushed material quality, adjust extract pressure tank be 0.1MPa,
Temperature is 55 DEG C, after extracting 1h, stands 12h;
(3) by above-mentioned steps 2) extracting solution obtains filtered fluid by 80 mesh filter screens in extractor;
(4) the 1/3 of volume is concentrated the filtrate to, can be obtained eucalyptus leaf extract.
Houttuynia extract described in foregoing invention Examples 1 to 4, faint scent leaf extract, peppermint leaf extract and
Extracting method of the loquat-leaf extract with eucalyptus leaf extract.
Molasses described in foregoing invention Examples 1 to 4 are obtained with following methods:
(1) a certain amount of molasses are taken, brix is 25 ° of Bx, 15 times of water of addition stir 10min after being heated to 70 DEG C after diluting;
(2) supernatant is taken to can be obtained sugar of the present invention after 4000r/min is centrifuged 10min in molasses after above-mentioned dilution
Honey.
Infantile cough's syrup of the invention when in use, takes orally, 1ml of child within six months, and six months extremely less than
2ml of one full year of life child, 2~4ml of one-year-old to five years old child, 3 times a day.
In order to verify the curative effect of infantile cough's syrup of the present invention, case test is done, curative effect judging standard: cured as symptom
It completely disappears, takes effect and disappear substantially for cardinal symptom, invalid is not change with before treatment.Test situation is to look for six group 50 respectively
In name patient, male 25 is female 25,5 years old maximum, and 1 years old minimum, wherein two groups of control group, use 999 P-Cymenes respectively
(control group 1) and sunflower P-Cymene (control group 2) carry out check experiment, and control group dosage is same embodiment, use 5
Result such as the following table 1 after~7 days:
Embodiment | It cures | It takes effect | In vain | Efficient (%) |
Embodiment 1 | 26 | 16 | 8 | 84% |
Embodiment 2 | 33 | 15 | 2 | 96% |
Embodiment 3 | 29 | 14 | 7 | 86% |
Embodiment 4 | 30 | 15 | 5 | 90% |
Control group 1 | 26 | 15 | 9 | 82% |
Control group 2 | 23 | 15 | 12 | 76% |
As shown in Table 1, the effective percentage in Examples 1 to 4 is 84% or more: and 26 are cured in control group 1,15 are cured, is seen
Effect 41, no effect 9, cure rate 52%, effective percentage 82%;23 are cured in control group 2, are cured 15, are taken effect 38, invalid 12
Example, cure rate 46%, effective percentage 76%;In short, the cure rate and effective percentage of Examples 1 to 4 are above control group 1 and 2, it was demonstrated that should
Combination drug syrup concertedness is higher, and drug effect is good, can be used for treating cold in children cough, and without any side effects use is pacified
Entirely.
Claims (6)
1. a kind of infantile cough's syrup and preparation method thereof, which is characterized in that the formula composition of infantile cough's syrup and part
Number are as follows: 1~2 part of eucalyptus leaf extract, 2~4 parts of houttuynia extract, 1~4 part of faint scent leaf extract, peppermint leaf extract 2
~5 parts, 0.1~0.2 part of benzoic acid, 30~50 parts of molasses, 5~10 parts of loquat-leaf extract.
2. a kind of preparation method of infantile cough's syrup, which comprises the steps of:
(1) first eucalyptus leaf extract, houttuynia extract, faint scent leaf extract, peppermint leaf extract and loguat leaf are extracted
It stirs evenly, is placed in 5~10 DEG C of freezer spare after being filtered after refrigerating 24~48h after object mixing;
(2) lead to 105~120 DEG C of sterilizings of steam after heating molasses in high-pressure sterilizing pot, keep the temperature 0.5~1.5h, heat preservation terminates
It is refiltered after 0~3 DEG C of 10~20min of standing of ice bath rear spare;
(3) by above-mentioned steps 1) mixture be added step 2 molasses in, after 2000~5000r/min homogeneous, 5~10min to
With;
(4) by above-mentioned steps 3) 200~500r/min of mixed liquor stir and be slowly added into benzoic acid mix after can be prepared into one
Kind infantile cough's syrup.
3. a kind of infantile cough's syrup according to claim 2 and preparation method thereof, which is characterized in that the eucalyptus
Leaf extract is extracted with following methods:
(1) investment Universalpulverizer is crushed to 30~50 mesh after cleaning eucalyptus leaves;
(2) crushed material is placed in extractor, the water of 15~30 times of crushed material quality is added, adjusting and extracting pressure tank is 0.1
~0.2MPa, temperature are 65~75 DEG C, after extracting 1h~2h, stand 12h;
(3) by above-mentioned steps 2) extracting solution obtains filtered fluid by 120~160 mesh filter screens in extractor;
(4) the 1/3~1/4 of volume is concentrated the filtrate to, can be obtained eucalyptus leaf extract.
4. a kind of infantile cough's syrup according to claim 3 and preparation method thereof, which is characterized in that the eucalyptus
Leaf can be replaced cordate houttuynia, faint scent leaf, dried peppermint leaf, loguat leaf.
5. a kind of infantile cough's syrup according to claim 2 and preparation method thereof, which is characterized in that the molasses
For one of beet molasses, cane molasses, grape molasses or mixture.
6. a kind of infantile cough's syrup according to claim 2 and preparation method thereof, which is characterized in that the molasses
It is to be obtained with following methods:
(1) a certain amount of molasses are taken, brix is 20~30 ° of Bx, 10~20 times of water of addition stir after being heated to 70~80 DEG C after diluting
Mix 5~15min;
(2) supernatant is taken to can be obtained the present invention after 3000~5000r/min is centrifuged 5~15min in molasses after above-mentioned dilution
The molasses.
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CN (1) | CN109700880A (en) |
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2019
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Application publication date: 20190503 |