CN1096865C

CN1096865C - Chinese patent drug-Yibao for treating diabetes

Info

Publication number: CN1096865C
Application number: CN99119548A
Authority: CN
Inventors: 庞树梅; 刘淑珍
Original assignee: JULONG INST OF DIABETES SHANXI
Current assignee: JULONG INST OF DIABETES SHANXI
Priority date: 1999-09-03
Filing date: 1999-09-03
Publication date: 2002-12-25
Anticipated expiration: 2019-09-03
Also published as: CN1248470A

Abstract

The present invention discloses a Chinese patent medicine for curing diabetes, which is an oral Chinese patent medicine prepared from 11 Chinese medicine materials of Chinese magnoliavine fruit, rhizoma anemarrhenae, rehmannia root, Chinese yam, red sage root, cornus fruit, ophiopogon root, astragalus root, Chinese gall, coptis root and snakegourd root. By the wide view of the prescription, the Chinese patent medicine has the functions of enriching yin, clearing away heat, promoting fluid production, allaying thirst, promoting blood circulation and removing blood stasis, which is in accordance with recognition on the pathogenic mechanism of diabetes of traditional Chinese medicine. The present invention has the advantages of treatment of both manifestations and root causes of diseases, obvious clinical therapeutic effect, high effective rate and no toxic or side effect.

Description

A kind of Chinese patent medicine for the treatment of diabetes---pancreas treasured

The present invention relates to a kind of medicine for the treatment of diabetes, specifically is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.

Diabetes are the doctor trained in Western medicine name of disease, and the traditional Chinese medical science is called diabetes, and domestic sickness rate is about 1%, and the trend that increases is year by year arranged, and case fatality rate is only second to malignant tumor and cardiovascular diseases, is to jeopardize the third-largest disease of human life.Though the medicine of western medical treatment primary disease is a lot of at present, curative effect is not consolidated, and side effect is big, and for a long time with producing antibody, biological activity reduces as insulin, and dosage increases, and produces hyperinsulinemia, impels microangiopathies to take place and development; The Chinese patent medicine that some treatment diabetes are also arranged, but because effect is not fairly obvious, and the patient still has to depend on some Western medicine, as " insulin ", generally speaking diabetes are diseases of a kind of refractory.

Purpose of the present invention aims to provide the Chinese patent medicine of the little treatment diabetes of a kind of good effect and toxic and side effects.

Solution of the present invention is based on motherland's medical science to diabetes and pathogenetic understanding of complication and Therapeutic Principle, achieve with reference to modern pharmacological research, from motherland's medical treasure-house, filter out nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, the Chinese herbal medicine of blood circulation promoting and blood stasis dispelling is made oral Chinese patent medicine by traditional Chinese medical science prescription theory.

Chinese patent medicine of the present invention is made (consumption is a weight portion) by following traditional Chinese medicine raw:

Fructus Schisandrae Chinensis 8-12 part Rhizoma Anemarrhenae 8-12 part Radix Rehmanniae 8-12 part Rhizoma Dioscoreae 8-12 part

Radix Salviae Miltiorrhizae 8-12 part Fructus Corni 8-12 part 12-18 Radix Ophiopogonis part Radix Astragali 12-18 part

Galla Chinensis 12-18 part Rhizoma Coptidis 12-18 part Radix Trichosanthis 12-18 part

Above-mentioned Chinese medicine raw materials by weight proportion is made oral Chinese patent medicine.

The optimum weight proportioning of Chinese patent medicine of the present invention is:

10 parts of 10 portions of Rhizoma Dioscoreaes of 10 portions of Radix Rehmanniae of 10 parts of Rhizoma Anemarrhenaes of Fructus Schisandrae Chinensis

15 parts of 10 parts of Fructus Corni of Radix Salviae Miltiorrhizae, 15 parts of Radixs Astragali, 10 parts of Radix Ophiopogonis

15 parts of 15 parts of Radix Trichosanthis of 15 portions of Rhizoma Coptidis of Galla Chinensis

Above-mentioned Chinese medicine raw materials by weight proportion is made the oral Chinese patent medicine of capsule formulation.

The inventor thinks that diabetes are many because of eating and drinking without temperance, the plot imbalance, have few desires excessively due to, its clinical main performance is the dryness of the lung, gastric heat is suffered from a deficiency of the kidney, hot vehement impairment of YIN, the deficiency of YIN is scorching, therefore should be with nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, blood circulation promoting and blood stasis dispelling are the principles of formulating prescriptions.

The Rhizoma Anemarrhenae, Radix Rehmanniae, Radix Trichosanthis, Radix Ophiopogonis, Fructus Schisandrae Chinensis have the YIN supplementing and fluids increasing effect in the side, wherein also have hypoglycemic activity Radix Ophiopogonis; Rhizoma Coptidis has clearly rushes down, middle Jiao, the effect of reducing phlegm and internal heat; Rhizoma Dioscoreae strengthening the spleen the moon; The Fructus Corni essence of reinforcing the kidney; The Galla Chinensis pathogenic fire reducing of astringing the lung; The Radix Astragali, Radix Trichosanthis, Radix Ophiopogonis supplementing QI for promoting the production of body fluid; Radix Salviae Miltiorrhizae is a drug for invigorating blood circulation and eliminating stasis, and hypoglycemic activity is arranged.

Make a general survey of full side, the cooperation of ten Herba indigoferae Pseudotinctoriae is played nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, the effect of blood circulation promoting and blood stasis dispelling.

For showing that Chinese patent medicine of the present invention is to the treatment of diabetes effect, the present invention is through the clinical observation of 310 routine systems, I type 10 examples wherein, II type 300 examples, age of onset reckling 8 years old, the maximum 72 years old, medical history (discovery diabetes) first quarter moon-22 year, man's 209 examples, women 101 examples, its curative effect statistical result is as follows: after treating before the treatment of contrast symptom and blood glucose value before and after table 1 type i diabetes is treated

Not having has disease to alleviate disease no change disease to increase the weight of

(INS stops using) (INS decrement) (the INS amount is the same) " three-many-one-little " 35500 eye-blurreds 35140 fatigue and weaks 35500 constipation 62110 four limbs fiber crops pain 35320 hidrosis 53210 edema 71100 blood glucose values increase 0862 0INS and treat 35131 notes: 1, blood sugar detection adopts Japanese cassette rapid blood sugar instrument to measure, and the diabetes diagnosis standard adopts the WHO diagnostic criteria.

2,2 examples are not fed back so do not give statistics.

3, " asymptomatic " refers to treat asymptomatic person with before the present invention through insulin (INS).

4, " three-many-one-little " refers to polyphagia polydipsia polyuria, loses weight.Down together.Treatment back effective percentage before contrast symptom and the blood glucose value treatment before and after the treatment of table 2 type ii diabetes

There is (symptom) disease to alleviate disease no change disease and increases the weight of (%)

(INS stops using) (INS decrement) (the INS amount is the same) " three-many-one-little " 242 242 00 100 eye-blurreds 272 236 36 0 86.76 fatigue and weaks 248 246 20 99.19 constipation 86 80 60 93.02 four limbs fiber crops pain 152 140 12 0 92.11 blood sugar and/or 310 281 29 0 90.65 urine sugar values increase

Show that from above-mentioned clinical statistics data the present invention is to the control hyperglycemia, it is obvious to alleviate many symptoms of patient and complication effect, especially type i diabetes patient Shang Ke is had certain effect, the good medicine of a kind of treatment diabetes of can yet be regarded as.

The present invention has following advantage:

1, to select natural Chinese medicinal herb for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation, and nontoxic to human body.

2, the present invention need not decoct taking convenience.

3, treating both the principal and secondary aspects of a disease of the present invention, clinical efficacy is remarkable, and effective percentage reaches 90.65%.

Embodiment 1:

Raw material of Chinese medicine and the weight proportion of making this Chinese patent medicine are:

Fructus Schisandrae Chinensis 10kg Rhizoma Anemarrhenae 10kg Radix Rehmanniae 10kg Rhizoma Dioscoreae 10kg

Radix Salviae Miltiorrhizae 10kg Fructus Corni 10kg 15kg Radix Ophiopogonis Radix Astragali 15kg

Galla Chinensis 15kg Rhizoma Coptidis 15kg Radix Trichosanthis 15kg

Manufacture method: earlier will above-mentioned ten simply Chinese medicine to choose the decontamination choosing clean, oven dry is ground into fine powder, sieves, abundant mixing gets final product in the 0.3g capsule of again medicated powder being packed into.With cobalt 60 radiation sterilizations,, can make in the capsule 2-3 and preserve well with favorable moth-proof or fungus growth.

Function with cure mainly: QI invigorating, promote the production of body fluid, yin nourishing is quenched the thirst.

Usage and consumption: oral, one time 5,3 times on the one.

Storage: sealing, put shady and cool place.

Embodiment 2:

Fructus Schisandrae Chinensis 8kg Rhizoma Anemarrhenae 8kg Radix Rehmanniae 8kg Rhizoma Dioscoreae 8kg

Radix Salviae Miltiorrhizae 8kg Fructus Corni 8kg 12kg Radix Ophiopogonis Radix Astragali 12kg

Galla Chinensis 12kg Rhizoma Coptidis 12kg Radix Trichosanthis 12kg

Embodiment 3:

Fructus Schisandrae Chinensis 12kg Rhizoma Anemarrhenae 12kg Radix Rehmanniae 12kg Rhizoma Dioscoreae 12kg

Radix Salviae Miltiorrhizae 12kg Fructus Corni 12kg 18kg Radix Ophiopogonis Radix Astragali 18kg

Galla Chinensis 18kg Rhizoma Coptidis 18kg Radix Trichosanthis 18kg

Claims

1, a kind of Chinese patent medicine for the treatment of diabetes is characterized in that: raw material of Chinese medicine and the weight proportion of making this Chinese patent medicine are:

2, the Chinese patent medicine of treatment diabetes according to claim 1 is characterized in that: described raw material of Chinese medicine weight proportion is: