CN1159054C - Tongfuzhixie preparation - Google Patents
Tongfuzhixie preparation Download PDFInfo
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- CN1159054C CN1159054C CNB021154651A CN02115465A CN1159054C CN 1159054 C CN1159054 C CN 1159054C CN B021154651 A CNB021154651 A CN B021154651A CN 02115465 A CN02115465 A CN 02115465A CN 1159054 C CN1159054 C CN 1159054C
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Abstract
The present invention relates to a preparation for promoting catharsis and stopping diarrhea, which belongs to Chinese patent medicine for stopping diarrhea. The preparation for promoting catharsis and stopping diarrhea comprises a catharsis preparation and an anti-diarrhes preparation, which must be used cooperatively and are respectively prepared from a new formula comprising croton frost, raw rhubarb, stir-frying radish seed, ledebouriella root, coptis, roasting nutmeg, tangshen, stir-frying largehead atractylodes rhizome, etc. The catharsis preparation is used for promoting catharsis and eliminating pathogenic factors so as to eliminate the cause of diseases, the anti-diarrhes preparation is used for strengthening health and regulating organs so as to consolidate curative effects, and the two kinds of preparations enable the preparation for promoting catharsis and stopping diarrhea to have best curative effects by utilizing the two kinds of preparations cooperatively. The preparation for promoting catharsis and stopping diarrhea solves the problem that the existing medicine for treating chronic diarrhea does not have ideal curative effects. An effective rate is 100%, a cure rate is 83%, and the preparation for promoting catharsis and stopping diarrhea has unexpected effects on the treatment of chronic diarrhea.
Description
Technical field
The present invention relates to a kind of treatment diarrheal medicine, particularly relating to a kind of is the Chinese patent medicine of the treatment chronic diarrhea of feedstock production with the vegetable Chinese herbal medicine.
Background technology
Chronic diarrhea is a kind of common clinical, frequently-occurring disease.Cause that the diarrheal reason is a lot, the heresy of diseases caused by exogenous pathogenic factor cold-damp is invaded the intestines and stomach; The summertime heat-damp in summer injures gastrointestinal; Or stop blocking gastrointestinal in the eating and drinking without temperance, dyspepsia; With the passing of time acute chronic enteritis, bacterial enteritis, delay show effect or the like repeatedly.This course of disease is long, the lighter's some months, and weight person's many decades has had a strong impact on the healthy and work life of patient's body.Western medical treatment adopts antiinflammatory, astringent or styptic treatment for spontaneous sweating class medicine more, as bactrim, norfloxacin, metronidazole, rifampicin, Compound Diphenoxylate, CICANG etc.Its short term effect still can, but after the drug withdrawal disease recidivist is a lot of once more, and side effect is big.Chinese traditional treatment adopts method such as lightly ooze spleen invigorating, warming YANG, kidney tonifying, help digestion, as adopting SHENLING BAISHU SAN, Spleen Invigorating and Intestine Tonifying Pill, Fuzi Lizhong Wan, SISHEN WAN, lenitive pill etc.Its effect is good than Western medicine, and side effect is little, is not very good but still exist curative effect, and treatment time is long, and patient such as can not adhere at drawback.
Summary of the invention
Purpose of the present invention is exactly in order to provide a kind of late result good, the pure Chinese medicinal preparation that cure rate is high.
Tongfuzhixie preparation of the present invention comprises the purging FU-organs agent and the diarrhea two parts that must share, and all is raw material with the Chinese herbal medicine.Wherein the purging FU-organs agent mainly be with the Semen Crotonis Pulveratum be raw material routinely formulation method be prepared into Chinese patent medicine; Diarrhea is with the following materials of weight proportions Chinese patent medicine that is prepared into of formulation method routinely:
Radix Saposhnikoviae 2-8 part Rhizoma Coptidis 3-7 part
Rhizoma Zingiberis 3-7 part Nutmeg 3-8 part
Radix Codonopsis 5-12 part Rhizoma Atractylodis Macrocephalae (parched) 5-10 part
Poria 5-10 part Radix Paeoniae Alba (parched) 5-12 part
Rhizoma dioscoreae (parched) 5-15 part Pericarpium Citri Reticulatae 2-8 part
The present invention can also add Radix Et Rhizoma Rhei, Rhizoma Zingiberis, Semen Raphani (parched) in the purging FU-organs agent, then the weight proportion of each raw material is at this moment:
The purging FU-organs agent:
Semen Crotonis Pulveratum 0.3-1.8 part Rhizoma Zingiberis 0.7-2.0 part
Radix Et Rhizoma Rhei 0.5-1.5 part Semen Raphani (parched) 0.2-0.8 part
Diarrhea: the weight proportion of each raw material is same as aforementioned.
Preparing medicine preferred weight ratio range of the present invention is:
The purging FU-organs agent:
Semen Crotonis Pulveratum 0.5-1.0 part Rhizoma Zingiberis 1.0-1.5 part
Radix Et Rhizoma Rhei 0.5-1.0 part Semen Raphani (parched) 0.4-0.6 part
Diarrhea:
Radix Saposhnikoviae 5-7 part Rhizoma Coptidis 4-6 part
Rhizoma Zingiberis 4-6 part Nutmeg 5-7 part
Radix Codonopsis 6-10 part Rhizoma Atractylodis Macrocephalae (parched) 6-9 part
Poria 6-8 part Radix Paeoniae Alba (parched) 7-10 part
Rhizoma dioscoreae (parched) 6-10 part Pericarpium Citri Reticulatae 4-6 part
The optimum weight proportioning of medicament of the present invention is:
The purging FU-organs agent:
1.2 parts of 1.7 portions of Rhizoma Zingiberiss of Semen Crotonis Pulveratum
0.5 part of 1.5 parts of Semen Raphani (parched) of Radix Et Rhizoma Rhei
Diarrhea:
5 parts of 5 portions of Rhizoma Zingiberiss of 5 portions of Rhizoma Coptidis of Radix Saposhnikoviae
9 parts of 10 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 8 parts of Radix Codonopsis of Nutmeg
14 parts of 12 parts of Rhizoma dioscoreae (parched)s of 8 parts of Radix Paeoniae Alba (parched)s of Poria
6 parts of Pericarpium Citri Reticulataes
Tongfuzhixie preparation of the present invention formulation method is routinely made multiple dosage forms such as powder, electuary, capsule, oral liquid, honeyed pill, the watered pill.
In the present invention's prescription, also available Fructus Crotonis replaces Semen Crotonis Pulveratum, but used in amounts converts.
The present invention attacks by pathogenic factor with the purging FU-organs agent earlier, and vital QI recovered after pathogens eliminated just meets the aim of " interior warp " " the six hollow viscera must keep its unobstructed ".And then the diarrhea made from air making-up and spleen enlivening, the astringent or styptic treatment for spontaneous sweating class medicine of yang invigorating.Because two parts medicine share, uncharm earlier, after set upright, the barrier of benefiting has mutually substantially exceeded the curative effect of present used diarrhea, and the chronic diarrhea cure rate is improved greatly, accelerates healing speed.As taking precautions against flood harm, though only by impound certain flooding action is arranged, effect is also not obvious, the measure that neither effect a radical cure.Have only dredging river (being equivalent to the eliminating evil effect of purging FU-organs agent purging FU-organs), in time built flood dam (being equivalent to the diarrhea effect), just can receive the effect of rapid healing and radical cure.The present invention's novelty of filling a prescription is attacked heresy under rushing down with logical cathartic earlier, adds to consolidate with diarrhea to deal with problems arising from an accident again, and has first opened the beginning for the treatment of the used medicine of chronic diarrhea, has obtained beyond thought effect.
Drug use method of the present invention:
Earlier use the purging FU-organs agent, wait to rush down times for five to six times after, reuse diarrhea of the present invention.The purging FU-organs agent was a course of treatment in per 15 days, and obey once per course of treatment, warm water delivery service, and diarrhea was a course of treatment in per 15 days, day clothes two to three times, warm water delivery service, stool containing pus and blood person prohibits clothes.
For showing the effect of Drug therapy chronic diarrhea of the present invention, the present invention has selected traditional Chinese medical science gastrointestinal training to show effect repeatedly more than February, and the patient of eliminating tumor, liver, gallbladder, pancreas disease totally 120 examples carries out system's clinical observation, wherein male 83 examples, woman's 37 examples, reckling 16 years old, the maximum 73 years old, and select the suitable chronic diarrhea patient of medical history, the state of an illness, age, sex 30 examples to be matched group simultaneously, wherein male 19 examples, woman's 11 examples, reckling 19 years old, the maximum 70 years old.
Therapeutic Method:
Test group: first quarter moon before treatment, other diarrhea of stopping using are taken medicine of the present invention.Instructions of taking: earlier use the purging FU-organs agent, wait to rush down times for five to six times after, reuse diarrhea of the present invention.The purging FU-organs agent is a capsule, every heavy 0.3 gram, and per 15 days is a course of treatment, and obey once (2) per course of treatment, and warm water delivery service, diarrhea are powder, 10 grams/time, day clothes 2-3 time, warm water delivery service, 15 days is a course of treatment.Matched group: clothes Spleen Invigorating and Intestine Tonifying Pill (market is on sale), each 6-9 gram, every day 2 times, the course of treatment is identical with test group.
Criterion of therapeutical effect
Criterion of therapeutical effect is drafted in diagnostic criteria with reference to chronic diarrhea in the People's Health Publisher publishes, Chen Haozhu is edited " internal medicine ".Recovery from illness: clinical symptom disappearance, enteroscopy recover normal, follow up a case by regular visits to and do not recur half a year.Produce effects: times of defecation is normal, and double disease disappears substantially, meets times of defecation such as polyphagia, cold, the surfeit delicious food of drink by chance and increases, and enteroscopy is normal substantially.Take a turn for the better: just time obviously minimizing, the intestinal mirror is still seen intestinal mucosa mild hyperaemia edema.Invalid: suffer from diarrhoea as before, double disease still exists, and the intestinal mirror does not have change.
Clinical test results is as showing:
Two groups Comparison of therapeutic
The total routine number of group is cured the total significant figure (%) of (%) produce effects (%) improvement (%) invalid (%)
120 people, 100 people (83) 15 people (125) 5 people (4.5) 0 people 120 people (100) are organized in treatment
Matched group 30 people 3 people (10) 10 people (33.3) 15 people (50) 2 people (6.7) 28 people (93.3)
X
2Check, two groups are compared P ∠ 0.01
Test statistics shows that medicine of the present invention is done therapeutic test to 120 chronic diarrhea patients, obtains cure rate 83%, and total effective rate reaches 100%, apparently higher than matched group.
The specific embodiment
Embodiment 1
The preparation of purging FU-organs agent: get Semen Crotonis Pulveratum 30 gram, after 60C ° of cold drying, be crushed to 80 orders, routinely formulation method make capsule the purging FU-organs capsule.
Diarrhea takes by weighing raw material by following proportioning:
6 kilograms of 6 kilograms of Rhizoma Zingiberiss of 2.5 kilograms of Rhizoma Coptidis of Radix Saposhnikoviae
5 kilograms of 12 kilograms of Rhizoma Atractylodis Macrocephalae (parched)s of 3.5 kilograms of Radix Codonopsis of Nutmeg
15 kilograms of 5.6 kilograms of Rhizoma dioscoreae (parched)s of 6 kilograms of Radix Paeoniae Alba (parched)s of Poria
3 kilograms of Pericarpium Citri Reticulataes
Wherein, with the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Dioscoreae difference parching to brown, Semen Myristicae is simmered fuel-displaced (each embodiment all carries out this kind processing) with face.
More than the cold drying respectively of each medicine, pulverize the back and mix, prepare the honeyed pill method routinely and be prepared into the honeyed pill dosage form.
Embodiment 2
Purging FU-organs agent preparation method:
Get Semen Crotonis Pulveratum 5 gram, Radix Et Rhizoma Rhei 8 grams, Rhizoma Zingiberis 10 grams, Semen Raphani (parched) 4 grams (Semen Raphani is put into iron pan and fries to fragrance, and is as follows).Surplus medicine after the Semen Raphani fried and the cold drying mixed pulverize, controlling the water circulation ball method is prepared into watered pill routinely.
The preparation method of diarrhea:
Take by weighing 8 kilograms of Radix Saposhnikoviaes, 5 kilograms of Rhizoma Coptidis, 4.5 kilograms of Rhizoma Zingiberiss, 5 kilograms of Nutmegs, 5 kilograms of Radix Codonopsis, 8 kilograms of Rhizoma Atractylodis Macrocephalae (parched)s, 10 kilograms of Poria, 12 kilograms of Radix Paeoniae Alba (parched)s, 6 kilograms of Rhizoma dioscoreae (parched)s, 7 kilograms of Pericarpium Citri Reticulataes.More than each medicine after low temperature is done bath, mixing, pulverizing, prepare the electuary method routinely and be prepared into electuary.
Embodiment 3
Purging FU-organs agent preparation method: get Semen Crotonis Pulveratum 17 grams, Radix Et Rhizoma Rhei 15 grams, Rhizoma Zingiberis 12 grams, Semen Raphani (parched) 5 grams, formulation method is prepared into capsule routinely.
The preparation of diarrhea:
Get 5 kilograms of Radix Saposhnikoviaes, 5 kilograms of Rhizoma Coptidis, 5 kilograms of Rhizoma Zingiberiss, 8 kilograms of Nutmegs, 10 kilograms of Radix Codonopsis, 9 kilograms of Rhizoma Atractylodis Macrocephalae (parched)s, 8 kilograms of Poria, 12 kilograms of Radix Paeoniae Alba (parched)s, 14 kilograms of Rhizoma dioscoreae (parched)s, 6 kilograms of Pericarpium Citri Reticulataes, formulation method is prepared into powder routinely.
Claims (4)
1, a kind of Tongfuzhixie preparation is characterized in that partly being made up of the purging FU-organs agent that must share and diarrhea two:
A, purging FU-organs agent are to be raw material with the Semen Crotonis Pulveratum or to be the primary raw material Chinese patent medicine that is prepared into of formulation method routinely with the Semen Crotonis Pulveratum;
B, diarrhea are by the following weight proportion raw material Chinese patent medicine that is prepared into of formulation method routinely:
Radix Saposhnikoviae 2-8 part Rhizoma Coptidis 3-7 part
Rhizoma Zingiberis 3-7 part Nutmeg 3-8 part
Radix Codonopsis 5-12 part Rhizoma Atractylodis Macrocephalae (parched) 5-10 part
Poria 5-10 part Radix Paeoniae Alba (parched) 5-12 part
Rhizoma dioscoreae (parched) 5-15 part Pericarpium Citri Reticulatae 2-8 part.
2, Tongfuzhixie preparation according to claim 1 is characterized in that purging FU-organs agent raw material also comprises Radix Et Rhizoma Rhei, Rhizoma Zingiberis and Semen Raphani (parched), and its raw material weight proportioning is:
Semen Crotonis Pulveratum 0.3-1.8 part Rhizoma Zingiberis 0.7-2.0 part
Radix Et Rhizoma Rhei 0.5-1.5 part Semen Raphani (parched) 0.2-0.8 part.
3, Tongfuzhixie preparation according to claim 2, wherein the weight proportion of each raw material is:
A, purging FU-organs agent:
Semen Crotonis Pulveratum 0.5-1.0 part Rhizoma Zingiberis 1.0-1.5 part
Radix Et Rhizoma Rhei 0.5-1.0 part Semen Raphani (parched) 0.4-0.6 part
B, diarrhea:
Radix Saposhnikoviae 5-7 part Rhizoma Coptidis 4-6 part
Rhizoma Zingiberis 4-6 part Nutmeg 5-7 part
Radix Codonopsis 6-10 part Rhizoma Atractylodis Macrocephalae (parched) 6-9 part
Poria 6-8 part Radix Paeoniae Alba (parched) 7-10 part
Rhizoma dioscoreae (parched) 6-10 part Pericarpium Citri Reticulatae 4-6 part.
4, Tongfuzhixie preparation according to claim 2, wherein the weight proportion of each raw material is:
A, purging FU-organs agent:
1.2 parts of 1.7 portions of Rhizoma Zingiberiss of Semen Crotonis Pulveratum
0.5 part of 1.5 parts of Semen Raphani (parched) of Radix Et Rhizoma Rhei
B, diarrhea:
5 parts of 5 portions of Rhizoma Coptidis of Radix Saposhnikoviae
8 parts of 5 parts of Nutmegs of Rhizoma Zingiberis
9 parts of 10 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Radix Codonopsis
12 parts of 8 parts of Radix Paeoniae Alba (parched)s of Poria
6 parts of 14 parts of Pericarpium Citri Reticulataes of Rhizoma dioscoreae (parched).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021154651A CN1159054C (en) | 2002-01-22 | 2002-01-22 | Tongfuzhixie preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021154651A CN1159054C (en) | 2002-01-22 | 2002-01-22 | Tongfuzhixie preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1367013A CN1367013A (en) | 2002-09-04 |
| CN1159054C true CN1159054C (en) | 2004-07-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021154651A Expired - Fee Related CN1159054C (en) | 2002-01-22 | 2002-01-22 | Tongfuzhixie preparation |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2241318B1 (en) | 2006-05-01 | 2012-12-19 | Napo Pharmaceuticals, Inc. | Method for treatment of constipation-predominant irritable bowel syndrome |
| CN1899435B (en) * | 2006-07-07 | 2010-09-22 | 唐麟 | Miao medicine powder for stopping diarrhea |
| CN105287683A (en) * | 2015-12-01 | 2016-02-03 | 蓬溪发联农牧有限公司 | Pharmaceutical composition for preventing and treating flatulence and diarrhea of rabbit and preparation and application of pharmaceutical composition |
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| CN1367013A (en) | 2002-09-04 |
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Granted publication date: 20040728 Termination date: 20100222 |