CN1679892A - Oral liquid for treating cancer and preparation thereof - Google Patents
Oral liquid for treating cancer and preparation thereof Download PDFInfo
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- CN1679892A CN1679892A CN 200510017313 CN200510017313A CN1679892A CN 1679892 A CN1679892 A CN 1679892A CN 200510017313 CN200510017313 CN 200510017313 CN 200510017313 A CN200510017313 A CN 200510017313A CN 1679892 A CN1679892 A CN 1679892A
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Abstract
A Chinese medicine in the form of oral liquid for treating cancers is prepared from 17 Chinese-medicinal materials including honeysuckly flower, oyster shell, safflower, oldenlandia, etc. Its preparing process is also disclosed.
Description
One, technical field
The present invention relates to a kind of oral liquid and production method thereof of treatment cancer of clinical practice.
Two, background technology
Cancer is a kind of common frdquently encountered disease, relates to whole systemic disease, and the healing difficulty is big, and people's healthy and life security in serious harm.At present, the medicine of treatment cancer is a lot, but effect is not good enough, and its fundamental cause is to catch at all, with symptomatic treatment.Cancer says medically that therefrom it forms not outer vital QI being weakened and pathogen being violent, and is weakened body resistance then anti-evil low, becomes the body of susceptible, and the domination of pathogen then comprises poison Shengs, expectorant knot, blood stasis and the knot of materialize is poly-, and the position internal organs difference that its knot gathers forms various cancerous protuberances; Return its occurrence cause, many because chronic dietary does not save disorder of emotion, excessive impairment caused by overstrain, or experience external evil poison, cause the body imbalance between YIN and YANG, function is unusual, thereby the stagnation of QI, blood stasis, dyspepsia, wet poly-, a series of pathological changes such as expectorant is tied, the gathering of evil poison occur, finally forms cancerous protuberance.The generation of cancerous protuberance is just in various external paathogenic factors, and long term is in human body, and body can not eliminate the influence of these paathogenic factors and the qi depression to blood stasis that takes place, the phlegm-damp cohesion, and evil poison pents up, zang-fu disharmony.Therefore, the rule of treatment of controlling cancer set upright outward, eliminating evil two big rules.Chinese medicine and pharmacy is a big treasure-house, has the unique effects of the various difficult diseases of treatment, and rich in natural resources is arranged.So, can utilize the principle of Chinese materia medica, formulate out a kind of effective cancer curing medicine?
Three, summary of the invention
At above-mentioned situation, the present invention's purpose just provides a kind of oral liquid (claiming cancer to disappear again) and production method thereof for the treatment of cancer, effectively solve the treatment for cancer problem, the technical scheme of its solution is, according to pathogenesis of cancer reason and the Chinese medicine and pharmacy principle of curing the disease, oral liquid adopts Herba Aristolochiae Mollissimae, Flos Lonicerae, Poria, Concha Ostreae, Flos Carthami, Herba Hedyotidis Diffusae, Bulbus Fritillariae Thunbergii, rhizoma sparganic, Caulis Spatholobi, Rhizoma Curcumae, Herba Scutellariae Barbatae, Herba Salviae Chinensis, Radix Salviae Miltiorrhizae, Radix Ilicis Pubescentis, Cordyceps, Grifola frondosa, breaking trachytectum of glossy ganoderma powder and fermentation liquid are made, its production method is, by the Chinese medicine processing requirement, the Herba Aristolochiae Mollissimae that has cooked, Flos Lonicerae, Poria, Concha Ostreae, Flos Carthami, Herba Hedyotidis Diffusae, Bulbus Fritillariae Thunbergii, rhizoma sparganic, Caulis Spatholobi, Rhizoma Curcumae, Herba Scutellariae Barbatae, Herba Salviae Chinensis, Radix Salviae Miltiorrhizae, Radix Ilicis Pubescentis, after Cordyceps is inserted and is soaked in the water, decoction filtering gets decocting liquid, place water to soak Grifola frondosa and breaking trachytectum of glossy ganoderma powder simultaneously, get filtrate, merge two filtrates, cooling back adding fermentation liquid mixing leaves standstill and gets final product, prescription of the present invention is scientific and reasonable, production method is simple, take effective, have no adverse reaction, absorb soon, mouthfeel is good, and the patient easily accepts, its popularization is taken, and must bring glad tidings for the cancer patient.
Four, the specific embodiment
Below in conjunction with concrete condition and embodiment the specific embodiment of the present invention is elaborated.
Provided by prescription, oral liquid of the present invention is to be made by by weight Herba Aristolochiae Mollissimae 27-33 part, Flos Lonicerae 27-33 part, Poria 27-33 part, Concha Ostreae 35-45 part, Flos Carthami 27-33 part, Herba Hedyotidis Diffusae 55-65 part, Bulbus Fritillariae Thunbergii 45-54 part, rhizoma sparganic 18-22 part, Caulis Spatholobi 27-33 part, Rhizoma Curcumae 27-33 part, Herba Scutellariae Barbatae 45-54 part, Herba Salviae Chinensis 45-54 part, Radix Salviae Miltiorrhizae 18-22 part, Radix Ilicis Pubescentis 13-17 part, Cordyceps 5-7 part, Grifola frondosa 250-350 part, breaking trachytectum of glossy ganoderma powder 250-350 part and water inventory 7000-8000 part and fermentation liquid.
Its best oral liquid is made by following component: Herba Aristolochiae Mollissimae 30g (g promptly restrains, and is as follows), Flos Lonicerae 30g, Poria 30g, Concha Ostreae 40g, Flos Carthami 30g, Herba Hedyotidis Diffusae 60g, Bulbus Fritillariae Thunbergii 50g, rhizoma sparganic 20g, Caulis Spatholobi 30g, Rhizoma Curcumae 30g, Herba Scutellariae Barbatae 50g, Herba Salviae Chinensis 50g, Radix Salviae Miltiorrhizae 20g, Radix Ilicis Pubescentis 15 g, Cordyceps 6g, Grifola frondosa 300g, breaking trachytectum of glossy ganoderma powder 300g, water inventory 7800ml (milliliter) and fermentation liquid are made.
Its production method is, to cook by weight by the Chinese medicine processing requirement: Herba Aristolochiae Mollissimae 27-33 part, Flos Lonicerae 27-33 part, Poria 27-33 part, Concha Ostreae 35-45 part, Flos Carthami 27-33 part, Herba Hedyotidis Diffusae 55-65 part, Bulbus Fritillariae Thunbergii 45-54 part, rhizoma sparganic 18-22 part, Caulis Spatholobi 27-33 part, Rhizoma Curcumae 27-33 part, Herba Scutellariae Barbatae 45-54 part, Herba Salviae Chinensis 45-54 part, Radix Salviae Miltiorrhizae 18-22 part, Radix Ilicis Pubescentis 13-17 part, Cordyceps 5-7 part is pulverized and is evenly immersed in 2600-3200 part water, soaked 18-24 hour down at 25-30 ℃, back slow fire boiling 1.5-2 hour is fried boiling, the elimination medicinal residues, drug filtrate in getting, standby, simultaneously with Grifola frondosa 250-350 part, the mixing of breaking trachytectum of glossy ganoderma powder 250-350 part places and adds water 4400-4800 part in the container, soaked 24 hours down at 24-28 ℃, mix with above-mentioned middle drug filtrate, after the cooling, add fermentation liquid, the accent pH value is 6.2-6.6, after the filtration, filling and sealing leaves standstill and got final product in 18-24 hour.
To make a dosage is example, its production method is: Herba Aristolochiae Mollissimae 30g, the Flos Lonicerae 30g, Poria 30g, Concha Ostreae 40g, Flos Carthami 30g, Herba Hedyotidis Diffusae 60g, Bulbus Fritillariae Thunbergii 50g, rhizoma sparganic 20g, Caulis Spatholobi 30g, Rhizoma Curcumae 30g, Herba Scutellariae Barbatae 50g, Herba Salviae Chinensis 50g, Radix Salviae Miltiorrhizae 20g, Radix Ilicis Pubescentis 15g, the Cordyceps 6g that cook are pulverized and evenly insert in the 3000ml water, under 28 ℃, soaked 20 hours, back slow fire boiling 1.5 hours is fried boiling, the elimination medicinal residues get filtrate for later use; Simultaneously Grifola frondosa 300g and breaking trachytectum of glossy ganoderma powder 300g are placed 4800ml water, soaked 24 hours down, merge evenly with above-mentioned middle drug filtrate at 26 ℃, adding fermentation liquid accent pH value is 6.5, behind the mistake 400 order filters (as filter screen), and fill, sealing, cultivation got final product in 24 hours under 26 ℃.
Above-mentioned said fermentation liquid is the leaven by weight ratio: water is 6-12: 100 are mixed and made into, 6-12: 100 is that every 6-12g leaven adds entry 100ml (leaven: water=6-12: 100).Leaven can adopt emulsifying agent, inferior her yeast, Wei Er to rein in yeast, Ke Naman yeast.Its function of fermentation liquid is: the one, transfer pH value, and control acid-base value in the production process, making pH value is 6.2-6.6; The 2nd, putting has Fermentation in the medicinal liquid, is beneficial to the absorption of medicine and takes the raising curative effect.
In said medicine, select Herba Aristolochiae Mollissimae, Flos Lonicerae, Poria, Concha Ostreae, Flos Carthami, Herba Hedyotidis Diffusae, Bulbus Fritillariae Thunbergii, rhizoma sparganic heat-clearing and toxic substances removing for use, regulating QI and lowering the adverseness, anticancer, antiinflammatory, antibiotic, antiviral, anti-frightened, diuresis, nourishing, analgesia, antitussive, resolving depression, blood pressure lowering, blood fat reducing, quicken the intestines and stomach smooth muscle wriggling, facilitating digestion absorbs, raise immunity; Select Caulis Spatholobi, Rhizoma Curcumae, Herba Scutellariae Barbatae, Herba Salviae Chinensis, Radix Salviae Miltiorrhizae, Radix Ilicis Pubescentis, Cordyceps replenishing QI to invigorate the spleen for use, nourishing YIN and supplementing blood, warming the kidney to invigorate YANG, YIN nourishing and the production of body fluid promoting is regulated the blood oxygen demand, anti-radiation, blood flow increasing, spasmolytic peacefulness, blood circulation promoting and blood stasis dispelling; Grifola frondosa is nutritious, and medical value is very high, and building body has very strong immunity to tumor; The breaking trachytectum of glossy ganoderma powder is that the powder that the breaking cellular wall of its spore is made has good medical value in the Ganoderma training is grown; The leaven invigorating the stomach and promoting digestion is beneficial to drug absorption, instant effect, and full component interacts, the broken resistance of blood stasis dispelling, hard masses softening and resolving, strong health, the purpose of efficient fast scooter treatment cancer.Clinical practice is also just so:
(1) standard of selection case
All symptoms with various cancer patients all can be used as the treatment target of selecting case.
(2) diagnostic criteria
Press the clinical research guideline of the new Chinese medicine treatment primary hepatocarcinoma of health ministry formulation in 1993 and establish Chinese and western medicine diagnostic criteria and test case standard.
(3) therapeutic scheme
Each oral 150ml, three times on the one, after ante cibum all can, oral dose must not be less than 400ml on 1st, was no more than 500ml at most, 30 days is a course of treatment, generally serveing on three courses of treatment can take effect or obviously take effect, remission is even complete obiteration.
(4) treatment evaluation criteria
Press the evaluation criteria execution that Ministry of Public Health is formulated.
Produce effects: symptom is alleviated fully or is disappeared, and reaches life cycle more than 5 years.
Effectively: symptom is partly alleviated, and life cycle is more than 6 months.
Invalid: symptom does not have any improvement, and the trend of deterioration is arranged, even the short time is promptly dead.
(5) statistical procedures
Physical data: with breast carcinoma, pulmonary carcinoma, hepatocarcinoma is that treatment target carries out observation of curative effect.
Case 180 examples, separating tests group and matched group, test group 100 examples, matched group 80 examples, each 50 example of test group men and women, each 40 example of matched group men and women, minimum 16 years old of age, maximum 65 years old, two groups of state of an illness basically identicals, the course of disease is the shortest 3 months, and is the longest 3 years, and test group is obeyed oral liquid of the present invention on request, matched group clothes fluorouracil+vincristine+cyclophosphamide, two groups of statistical procedures p＞0.05, but comparative had, concrete condition such as following table:
1, controls back life cycle
| Life cycle | 6 months | 1 year | 2 years | 3 years | 4 years | 5 years | More than 5 years |
| Test group (people) | ???1 | ????5 | ????17 | ????27 | ????19 | ????10 | ????21 |
| Matched group (people) | ???4 | ????14 | ????15 | ????22 | ????14 | ????6 | ????5 |
2, the focus index is improved situation
| Situation | Alleviate fully | Part is alleviated | Stable | |||||
| Test group (people) | ??50 | ??50％ | ??30 | ??30％ | ??19 | ??19％ | ????1 | ????1％ |
| Matched group (people) | ??2 | ??2.5％ | ??48 | ??60％ | ??26 | ??32.5％ | ????4 | ????5％ |
By The above results as can be seen, through treatment, take oral liquid of the present invention mean survival time (MST) more than 3.5 years, matched group is 2.5 years, the two has significant difference, focus is improved, and obey oral liquid of the present invention 50% conditions of patients is alleviated fully, and matched group has only 2.5% patient to alleviate fully, aspect relief of symptoms, oral liquid of the present invention has absolute advantage, alleviates patient's misery greatly, prolongs life span.
Case 1, a patients with lung cancer high fever, sensation of oppression over the chest with shortness of breath, cough with blood-flecked phlegm, inappetence, chest films showed left side hilus pulumonis has diameter 3cm similar round lump, through taking oral liquid of the present invention, pain relief after 15 days, the burning benzonatate subtracts, and diet increases, and body temperature is not high, the activity of getting up, continuous taking 3 months checks that through the CT sheet cancerous protuberance disappears.
Case 2, a liver cancer patient, heating repeatedly, hepatalgia, radioisotope scan, hepatomegaly, occupying lesion of right lobe, the visible 3cm of the CT sheet * irregular shade in 4cm size edge is diagnosed as hepatocarcinoma through liver puncture, and tongue is greasy in vain, thready and stringy pulse, with using oral liquid treatment of the present invention, 15 days pain reliefs, body temperature is normal, the CT examination cancerous protuberance is contracted to 1.0cm * 1.2cm after taking medicine 60 days, and the CT examination cancerous protuberance disappears after taking medicine 110 days.
Case 3, a papillary carcinoma patient, right breast is sagging, and the breast colour of skin is like Pericarpium Citri tangerinae, retracted nipple, atrophy has the crack, and red color visible granulation stone in the crack, B ultrasonic show mammary gland tumor 21 * 6 * 5.5cm; lesion examining is a cancer, the pale tongue no fur, and thready and weak pulse without strength is with taking oral liquid of the present invention; spirit is good after 18 days, has rosy cheeks moderate pulse and strong; the light red no fur of body of the tongue, appetite heighten, and scratchy causalgia disappears; the lump deliquescing is dwindled, and mammary gland tumor disappears after taking medicine 90 days, and breast restores substantially.
In a word, being shown by above-mentioned situation that oral liquid of the present invention has unique curative effect to the treatment cancer, succeed in developing, is to the creationary contribution of Chinese medicine and pharmacy, for the big treasure-house of Chinese medicine and pharmacy has increased new wonderful work, must bring benefit to the mankind.
Claims (6)
1, a kind of oral liquid for the treatment of cancer, it is characterized in that, be to be made by by weight Herba Aristolochiae Mollissimae 27-33 part, Flos Lonicerae 27-33 part, Poria 27-33 part, Concha Ostreae 35-45 part, Flos Carthami 27-33 part, Herba Hedyotidis Diffusae 55-65 part, Bulbus Fritillariae Thunbergii 45-54 part, rhizoma sparganic 18-22 part, Caulis Spatholobi 27-33 part, Rhizoma Curcumae 27-33 part, Herba Scutellariae Barbatae 45-54 part, Herba Salviae Chinensis 45-54 part, Radix Salviae Miltiorrhizae 18-22 part, Radix Ilicis Pubescentis 13-17 part, Cordyceps 5-7 part, Grifola frondosa 250-350 part, breaking trachytectum of glossy ganoderma powder 250-350 part and water inventory 7000-8000 part and fermentation liquid.
2, the oral liquid of treatment cancer according to claim 1, it is characterized in that, be to be made by said Herba Aristolochiae Mollissimae 30g, Flos Lonicerae 30g, Poria 30g, Concha Ostreae 40g, Flos Carthami 30g, Herba Hedyotidis Diffusae 60g, Bulbus Fritillariae Thunbergii 50g, rhizoma sparganic 20g, Caulis Spatholobi 30g, Rhizoma Curcumae 30g, Herba Scutellariae Barbatae 50g, Herba Salviae Chinensis 50g, Radix Salviae Miltiorrhizae 20g, Radix Ilicis Pubescentis 15g, Cordyceps 6g, Grifola frondosa 300g, breaking trachytectum of glossy ganoderma powder 300g, water inventory 7800ml and fermentation liquid.
3, the oral liquid of treatment cancer according to claim 1 and 2 is characterized in that, said fermentation liquid is the leaven by weight ratio: water is 6-12: 100 are mixed and made into.
4, the oral liquid of treatment cancer according to claim 3 is characterized in that, said leaven is that emulsifying agent, inferior her yeast, Wei Er are reined in yeast, Ke Naman yeast.
5, realize the production method of the oral liquid of the described treatment cancer of claim 1, it is characterized in that, it is to have cooked by weight by the Chinese medicine processing requirement: Herba Aristolochiae Mollissimae 27-33 part, Flos Lonicerae 27-33 part, Poria 27-33 part, Concha Ostreae 35-45 part, Flos Carthami 27-33 part, Herba Hedyotidis Diffusae 55-65 part, Bulbus Fritillariae Thunbergii 45-54 part, rhizoma sparganic 18-22 part, Caulis Spatholobi 27-33 part, Rhizoma Curcumae 27-33 part, Herba Scutellariae Barbatae 45-54 part, Herba Salviae Chinensis 45-54 part, Radix Salviae Miltiorrhizae 18-22 part, Radix Ilicis Pubescentis 13-17 part, Cordyceps 5-7 part is pulverized and is evenly immersed in 2600-3200 part water, soaked 18-24 hour down at 25-30 ℃, back slow fire boiling 1.5-2 hour is fried boiling, the elimination medicinal residues, drug filtrate in getting, standby, simultaneously with Grifola frondosa 250-350 part, the mixing of breaking trachytectum of glossy ganoderma powder 250-350 part places and adds water 4400-4800 part in the container, soaked 24 hours down at 24-28 ℃, mix with above-mentioned middle drug filtrate, after the cooling, add fermentation liquid, the accent pH value is 6.2-6.6, and after the filtration, filling and sealing left standstill 18-24 hour.
6, the production method of the oral liquid of treatment cancer according to claim 4, it is characterized in that, be that Herba Aristolochiae Mollissimae 30g, Flos Lonicerae 30g, Poria 30g, Concha Ostreae 40g, Flos Carthami 30g, Herba Hedyotidis Diffusae 60g, Bulbus Fritillariae Thunbergii 50g, rhizoma sparganic 20g, Caulis Spatholobi 30g, Rhizoma Curcumae 30g, Herba Scutellariae Barbatae 50g, Herba Salviae Chinensis 50g, Radix Salviae Miltiorrhizae 20g, Radix Ilicis Pubescentis 15g, the Cordyceps 6g that will cook pulverizes and evenly insert in the 3000ml water, under 28 ℃, soaked 20 hours, back slow fire boiling 1.5 hours is fried boiling, the elimination medicinal residues get filtrate for later use; Simultaneously Grifola frondosa 300g and breaking trachytectum of glossy ganoderma powder 300g are placed 4800ml water, soaked 24 hours down at 26 ℃, with above-mentioned in drug filtrate merge evenly, adding fermentation liquid, to transfer pH value be 6.5, cross 400 order filters after, fill, sealing was cultivated 24 hours down at 26 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100173139A CN100493586C (en) | 2005-01-12 | 2005-01-12 | Oral liquid for treating breast cancer, liver cancer or lung caner, and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100173139A CN100493586C (en) | 2005-01-12 | 2005-01-12 | Oral liquid for treating breast cancer, liver cancer or lung caner, and preparation thereof |
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| Publication Number | Publication Date |
|---|---|
| CN1679892A true CN1679892A (en) | 2005-10-12 |
| CN100493586C CN100493586C (en) | 2009-06-03 |
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| CNB2005100173139A Expired - Fee Related CN100493586C (en) | 2005-01-12 | 2005-01-12 | Oral liquid for treating breast cancer, liver cancer or lung caner, and preparation thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101134080B (en) * | 2006-08-30 | 2011-09-07 | 瑞普（天津）生物药业有限公司 | Compound traditional Chinese powder medicine for treating acute mastitis for cows |
| CN102498946A (en) * | 2011-11-03 | 2012-06-20 | 杨毅 | New technology for fermenting glossy ganoderma spores by edible and medicinal fungi biologically |
| CN105412500A (en) * | 2015-12-10 | 2016-03-23 | 葛莉 | Nursing traditional Chinese medicine combination for preventing relapse of postoperative breast cancer and preparation method thereof |
| CN105902865A (en) * | 2016-06-12 | 2016-08-31 | 潘纪红 | Traditional Chinese medicine preparation for treating tumors and preparation method thereof |
| CN107753819A (en) * | 2017-12-01 | 2018-03-06 | 广州市白云区天芳化妆品厂 | Prevent Chinese medicine composition and preparation method thereof of breast cancer with purposes and include its medicine |
| CN109123642A (en) * | 2018-09-27 | 2019-01-04 | 蔡勤 | With the integration of drinking and medicinal herbs food of zero injury repair gene therapy cancer |
-
2005
- 2005-01-12 CN CNB2005100173139A patent/CN100493586C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101134080B (en) * | 2006-08-30 | 2011-09-07 | 瑞普（天津）生物药业有限公司 | Compound traditional Chinese powder medicine for treating acute mastitis for cows |
| CN102498946A (en) * | 2011-11-03 | 2012-06-20 | 杨毅 | New technology for fermenting glossy ganoderma spores by edible and medicinal fungi biologically |
| CN105412500A (en) * | 2015-12-10 | 2016-03-23 | 葛莉 | Nursing traditional Chinese medicine combination for preventing relapse of postoperative breast cancer and preparation method thereof |
| CN105902865A (en) * | 2016-06-12 | 2016-08-31 | 潘纪红 | Traditional Chinese medicine preparation for treating tumors and preparation method thereof |
| CN107753819A (en) * | 2017-12-01 | 2018-03-06 | 广州市白云区天芳化妆品厂 | Prevent Chinese medicine composition and preparation method thereof of breast cancer with purposes and include its medicine |
| CN109123642A (en) * | 2018-09-27 | 2019-01-04 | 蔡勤 | With the integration of drinking and medicinal herbs food of zero injury repair gene therapy cancer |
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| Publication number | Publication date |
|---|---|
| CN100493586C (en) | 2009-06-03 |
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