CN1149097C

CN1149097C - Chinese patent medicine for curing diabetes

Info

Publication number: CN1149097C
Application number: CNB021099383A
Authority: CN
Inventors: 李常荣
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-01-23
Filing date: 2002-01-23
Publication date: 2004-05-12
Anticipated expiration: 2022-01-23
Also published as: CN1364632A

Abstract

The present invention discloses a Chinese patent medicine for curing diabetes. Eighteen Chinese medicinal herbs, such as radix adenophorae, pueraria root, trichosanthes powder, anemarrhenae, scrophularia root, coptis, scutellaria root, red sage root, rehmannia root, Chinese yam, pulp of a dogwood fruit, cortex moutan, gypsum, schisandra, astragalus root, prepared rhizome of rehmannia, lilyturf root, gardenia, etc., are used as raw materials to make the Chinese patent medicine for oral application. The eighteen Chinese medicinal herbs are properly matched with accurate dosage to jointly have the effects of nourishing Yin, clearing heat, relieving restlessness, purging pathogenic fire, expelling toxin, quenching thirst and conditioning internal organs, and conform to the principle of the Chinese medicine for curing the diabetes. The present invention cures both manifestation and root cause of the diabetes and has the advantages of conspicuous curative effect and no toxic side effect.

Description

A kind of Chinese patent medicine for the treatment of diabetes

One, technical field

The present invention relates to a kind of medicine for the treatment of diabetes, relating in particular to a kind of is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.

Two, background technology

Diabetes are common diseases of serious harm human health, and the traditional Chinese medical science is called diabetes, are because a kind of chronic progressive disease that the endocrine metabolism dysfunction is caused.Insulin lacks relatively or definitely in the blood flow of diabetics, causes sugar, fat, protein metabolism disorder, thereby causes the rising of hyperglycemia, hyperlipidemia and blood viscosity, extensively microangiopathies of the whole body can occur at middle and advanced stage.The sickness rate of present domestic diabetics is about 1%, and annual speed with 0.003% increases, and case fatality rate is only second to malignant tumor and cardiovascular diseases, is the third-largest disease that jeopardizes human life's health.

At present the medicine of western medical treatment diabetes is a lot, but its curative effect do not consolidate, and side effect is big, the insulin of using always as people has been used many can produce antibody, biological activity is reduced, if dosage increases, can produce hyperinsulinemia, impel microangiopathies to take place and development; The Chinese patent medicine that some treatment diabetes are also arranged, but because effect is not fairly obvious, the patient still has to rely on some Western medicine, as insulin, and some dosage form of Chinese patent medicine such as electuary, honeyed pill are not suitable for diabetics and use, reason is must sugaring just can impel the disintegrate of medicine grain in the electuary, then contains Mel in the honeyed pill.

Three, summary of the invention

Purpose of the present invention aims to provide the Chinese patent medicine of the little treatment diabetes of a kind of good effect and toxic and side effects.

Solution of the present invention is based on motherland's medical science to diabetes and pathogenetic understanding of complication and Therapeutic Principle, achieve with reference to modern pharmacological research, from motherland's medicine treasure-house, filter out that nourishing YIN and clearing away heat relieving restlessness, pathogenic fire purging toxin expelling are quenched the thirst, the Chinese herbal medicine of conditioning viscera function, make oral Chinese patent medicine by traditional Chinese medical science prescription theory.

Chinese patent medicine of the present invention is made (consumption is a weight portion) by following traditional Chinese medicine raw:

Radix Adenophorae (Radix Glehniae) 10-35 Radix Puerariae 15-25 Radix Trichosanthis 15-25 Rhizoma Anemarrhenae 15-25

Radix Scrophulariae 25-35 Rhizoma Coptidis 15-20 Radix Scutellariae 10-20 Radix Salviae Miltiorrhizae 10-20

Radix Rehmanniae 10-25 Rhizoma Dioscoreae 10-20 Fructus Corni 10-20 Cortex Moutan 10-20

Gypsum Fibrosum 15-25 Fructus Schisandrae Chinensis 10-20 Radix Astragali 20-35 Radix Rehmanniae Preparata 25-35

Radix Ophiopogonis 10-20 Fructus Gardeniae 15-20

Above-mentioned Chinese medicine raw materials by weight proportion is made oral Chinese patent medicine.

Formula optimization weight (part) ratio range of preparation Chinese patent medicine of the present invention is:

Radix Adenophorae (Radix Glehniae) 15-30 Radix Puerariae 15-20 Radix Trichosanthis 15-20 Rhizoma Anemarrhenae 15-20

Radix Scrophulariae 25-30 Rhizoma Coptidis 15-20 Radix Scutellariae 15-20 Radix Salviae Miltiorrhizae 10-15

Radix Rehmanniae 15-20 Rhizoma Dioscoreae 10-15 Fructus Corni 10-15 Cortex Moutan 10-15

Gypsum Fibrosum 15-20 Fructus Schisandrae Chinensis 10-15 Radix Astragali 25-30 Radix Rehmanniae Preparata 25-30

Radix Ophiopogonis 10-15 Fructus Gardeniae 15-20

The optimum weight of Chinese patent medicine of the present invention (part) proportioning is:

Radix Adenophorae (Radix Glehniae) 23 Radix Puerariaes 18 Radix Trichosanthis 18 Rhizoma Anemarrhenaes 18

Radix Scrophulariae 28 Rhizoma Coptidis 18 Radix Scutellariaes 18 Radix Salviae Miltiorrhizaes 13

The Radix Rehmanniae 18 Rhizoma Dioscoreaes 13 Fructus Corni 13 Cortex Moutans 13

Sub 13 Radixs Astragali, 28 Radix Rehmanniaes Preparata 28 of Gypsum Fibrosum 18 flavors

Radix Ophiopogonis 13 Fructus Gardeniae 18

Above-mentioned Chinese medicine raw materials by weight proportion is made the oral Chinese patent medicine of powder or capsule formulation.

Manufacture method: earlier above-mentioned 18 flavor Chinese medicines are chosen the decontamination choosing only, oven dry is ground into fine powder, sieves, and fully mixing promptly gets powder, with cobalt 60 radiation sterilizations, with favorable moth-proof or fungus growth.Promptly get capsule formulation during powder incapsulated.

Function with cure mainly: the nourishing YIN and clearing away heat relieving restlessness, the pathogenic fire purging toxin expelling quenches the thirst, the conditioning viscera function.

Cure mainly I, type ii diabetes.

Usage and consumption: oral, a 6g, 3 times on the one

Storage: put the sealing of shady and cool place and preserve

The inventor think diabetes be the deficiency of YIN, scorching due to, reach QI and blood with enriching yin boost qi unobstructed so we reuse Radix Adenophorae (Radix Glehniae), the Radix Astragali, Radix Scrophulariae, Radix Rehmanniae Preparata, YIN and YANG balancing; With the passing of time the deficiency of YIN gives birth to heat, the intenseness of heat impairment of body fluid, and body fluid deficiency is empty few, it is scorching and born fluid makes penis be able to nutrition so moisten with Radix Puerariae, Radix Trichosanthis, the Rhizoma Anemarrhenae, the Radix Rehmanniae, Fructus Schisandrae Chinensis; Add with Rhizoma Coptidis, Radix Scutellariae, Gypsum Fibrosum, clear its internal organs deficiency-heat of Fructus Gardeniae, heat is not just being hindered; " qi as the commander of blood, blood being the mother of qi ", the deficiency of vital energy promote unable and blood stasis, the meridian dredging with mending Radix Salviae Miltiorrhizae, Cortex Moutan, Rhizoma Dioscoreae, Fructus Corni, Radix Ophiopogonis its void.

Make a general survey of full side, our compatibility is proper, and dosage is accurate, follows traditional Chinese medical science traditional theory, and each medicine of distinguishing the flavor of cooperates and to play jointly that nourishing YIN and clearing away heat relieving restlessness, pathogenic fire purging toxin expelling are quenched the thirst, the effect of conditioning viscera function, meets the Therapeutic Principle of the traditional Chinese medical science to primary disease.

For showing that Chinese patent medicine of the present invention is to the treatment of diabetes effect, with Chinese patent medicine of the present invention 260 routine diabeticss are carried out system's clinical observation, wherein I type 12 examples, II type 248 examples, 12 years old of age of onset minimum, maximum 75 years old, medical history (diabetes are made a definite diagnosis by hospital) first quarter moon-30 year, male's 210 examples, women's 50 examples, its curative effect statistical result is as follows:

Table 1 clinical efficacy

Contrast before and after the treatment of table 2 type i diabetes

Project		Before the treatment		After the treatment
		Before the treatment		After the treatment			Asymptomatic	Symptom is arranged	Disease alleviates (INS stops using)	Disease no change (INS decrement)	Disease is increased the weight of (the INS amount is the same)
		Symptom	Three-many-one-little	3	5	6	Asymptomatic	Symptom is arranged	Disease alleviates (INS stops using)	Disease no change (INS decrement)		0	0
Blurred vision	3		Three-many-one-little	3	5	6	5	9	4	0		0	0
Blurred vision	3		Fatigue and weak	2	6	5	5	9	4	0	0	0
Constipation	6		Fatigue and weak	2	6	5	3	6	3	0	0	0
Constipation	6		Extremity fiber crops pain	3	2	2	3	6	3	0	2	0
Hyperhidrosis	5		Extremity fiber crops pain	3	2	2	3	5	1	0	2	0
Hyperhidrosis	5		Edema	7	1	2	3	5	1	0	0	0
Blood glucose increases	0		Edema	7	1	2	8	9	2	0	0	0
Blood glucose increases	0		The INS treatment		6	9	8	9	2	0	1	3	1

Annotate: 1, blood sugar detection adopts U.S.'s cassette liquid crystal display rapid blood sugar instrument to measure, and the diabetes diagnosis standard adopts the WHO diagnostic criteria.

2, " asymptomatic " refers to treat asymptomatic person with before the present invention through insulin (INS).

3, " three-many-one-little " refers to polydipsia, polyphagia, polyuria, loses weight.

Contrast before and after the treatment of table 3 type ii diabetes

Symptom and blood glucose	Before the treatment	After the treatment
	Before the treatment	After the treatment				Symptom is arranged	Disease alleviates	No change	Sx	Effective percentage
	Three-many-one-little	248	248	0	0	Symptom is arranged	Disease alleviates	No change	Sx	Effective percentage	100
Blurred vision	Three-many-one-little	248	248	0	0	216	210	6	0	97.1	100
Blurred vision	Fatigue and weak	248	246	2	0	216	210	6	0	97.1	99.1
Constipation	Fatigue and weak	248	246	2	0	102	90	12	0	89.7	99.1
Constipation	Numb limbs and tense tendons	163	158	5	0	102	90	12	0	89.7	90.3
Blood glucose value	Numb limbs and tense tendons	163	158	5	0	248	241	7	0	91.5	90.3

Show that from above-mentioned clinical statistics data the present invention is to the control hyperglycemia, the many complication that alleviate the patient have obvious effects, are a kind of good medicine of treatment diabetes.

The present invention has following advantage:

1, to select natural Chinese medicinal herb for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation.Utilize the comprehensive function treatment diabetes of the Chinese medicine of respectively distinguishing the flavor of, nontoxic to human body.

2, the present invention need not decoct taking convenience.

3, contain abundant water-soluble fibre in the medicament of the present invention, content of cellulose reaches 5%-20%, can promote gastrointestinal emptying, reduces sugar, fat absorption, helps blood glucose and reduces.Also contain abundant choline material and tanshinone material in this medicament, the tanshinone material can blood fat reducing, and blood viscosity lowering promotes microcirculation, increases the insulinemia infusate flow, helps the synthetic and secretion of insulin.

Four, the specific embodiment

Embodiment 1:

The raw material of Chinese medicine and the weight proportion that prepare this Chinese patent medicine are:

Radix Adenophorae (Radix Glehniae) 10kg Radix Puerariae 15kg Radix Trichosanthis 15kg Rhizoma Anemarrhenae 15kg

Radix Scrophulariae 25kg Rhizoma Coptidis 15kg Radix Scutellariae 10kg Radix Salviae Miltiorrhizae 10kg

Radix Rehmanniae 10kg Rhizoma Dioscoreae 10kg Fructus Corni 10kg Cortex Moutan 10kg

Gypsum Fibrosum 15kg Fructus Schisandrae Chinensis 10kg Radix Astragali 20kg Radix Rehmanniae Preparata 25kg

Radix Ophiopogonis 10kg Fructus Gardeniae 15kg

Embodiment 2:

Radix Adenophorae (Radix Glehniae) 35kg Radix Puerariae 25kg Radix Trichosanthis 25kg Rhizoma Anemarrhenae 25kg

Radix Scrophulariae 35kg Rhizoma Coptidis 20kg Radix Scutellariae 20kg Radix Salviae Miltiorrhizae 20kg

Radix Rehmanniae 25kg Rhizoma Dioscoreae 20kg Fructus Corni 20kg Cortex Moutan 20kg

Gypsum Fibrosum 25kg Fructus Schisandrae Chinensis 20kg Radix Astragali 35kg Radix Rehmanniae Preparata 35kg

Radix Ophiopogonis 20kg Fructus Gardeniae 20kg

Embodiment 3:

Gypsum Fibrosum 18 Fructus Schisandrae Chinensis 13 Radixs Astragali 28 Radix Rehmanniaes Preparata 28

Radix Ophiopogonis 13 Fructus Gardeniae 18

Claims

1, a kind of Chinese patent medicine for the treatment of diabetes is characterized in that: raw material of Chinese medicine and the weight proportion of making this Chinese patent medicine are:

Radix Ophiopogonis 10-20 Fructus Gardeniae 15-20

2, the Chinese patent medicine of treatment diabetes according to claim 1 is characterized in that: the weight proportion of described raw material of Chinese medicine is:

Radix Ophiopogonis 10-15 Fructus Gardeniae 15-20

3, the Chinese patent medicine of treatment diabetes according to claim 1 is characterized in that: the weight proportion of described raw material of Chinese medicine is:

Radix Ophiopogonis 13 Fructus Gardeniae 18