CN1370585A - Compound traditional Chinese medicine preparation for treating type 2 diabetes - Google Patents
Compound traditional Chinese medicine preparation for treating type 2 diabetes Download PDFInfo
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- CN1370585A CN1370585A CN02107203A CN02107203A CN1370585A CN 1370585 A CN1370585 A CN 1370585A CN 02107203 A CN02107203 A CN 02107203A CN 02107203 A CN02107203 A CN 02107203A CN 1370585 A CN1370585 A CN 1370585A
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Abstract
The invention discloses a compound traditional Chinese medicine preparation for treating type 2 diabetes, which is prepared into pills, powder and other dosage forms by taking natural traditional Chinese medicines such as kudzu root, Mongolian snakegourd root, swordlike atractylodes rhizome, figwort root, raw astragalus root, common yam rhizome, gypsum, cassia bark, prepared aconite, winged euonymus twig, Chinese polyphaga, Chinese taxillus twig, silkworm cocoon, stir-fried pangolin scales, leech, dragon blood, chinaroot greenbrier rhizome, common anemarrhena rhizome, fiveleaf gynostemma herb, rehmannia root, dwarf lilyturf tuber, red paeony root, Chinese wolfberry root-bark, prepared rhubarb and the like as raw materials. The invention has unique formula, low price and obvious treatment effect.
Description
Technical field
The present invention relates to a kind of is the Chinese patent medicine that raw material is made with the animals and plants Chinese crude drug, and specifically a kind of Chinese traditional compound medicine for the treatment of type 2 diabetes mellitus the invention still further relates to the preparation method of said preparation.
Background technology
Diabetes are a kind of common endocrine one metabolism diseases, are chronic progressive external and lifelong participation.It is characterized by beta Cell of islet dysfunction and insulin resistant.Wherein insulin resistant is the emphasis difficult problem of medical circle.The diabetes treatment by western medicine taking convenience, instant effect, shortcoming is can not be lasting, and certain toxic and side effects is arranged.The Chinese medicine effect is lasting, and toxic and side effects is little, mainly acts on islets of langerhans, promotes the β cell function, and enhancing body is to the sensitivity of insulin, insulin resistant material in the antagonist.
Summary of the invention
The object of the present invention is to provide a kind of blood sugar lowering that has, stablize blood glucose, strengthen the beta Cell of islet function, suppress insulin resistant, change blood dense, sticking, poly-, stagnant, the stasis of blood, block up, malicious state, prevent and treat complication, promote the Chinese traditional compound medicine of the treatment type 2 diabetes mellitus of sugar, fat, proteinic homergy.
Another object of the present invention provides the preparation method of said preparation.
Solution of the present invention is to be diagnosed as foundation with doctor trained in Western medicine, takes as the leading factor with tcm theory, seeks out the cross point of Chinese and western medicine.Huangdi's Internal Classics points out that " dirty crisp " is the key of primary disease, only could fall ill on the basis of " dirty crisp ", and modern medicine is thought because the β cell function reaches insulin resistant unusually.The wisdom flame that up-to-date theory and ancient record are being burnt same.
According at all times to the diabetes cause of disease, pathology and clinical understanding, the raise funds clinical experience in year surplus in the of 20 and folk remedy, successive dynasties empirical formula, state of Chinese medicine in Japan etc., the applicant creatively proposes dialectical combination and executes and control this traditional Chinese medical science new approaches, sum up and make and dialectically combine general and indivedual therapeutic schemes of taking into account mutually with differential diagnosis of diseases.It is fit to Most patients and adapts to special case, collection Replenishing QI and nourishing YIN, clearing heat and moistening dryness, the removing toxic substances of invigorating blood circulation, the kidney warming consolidating semen, Yin Yang balancing one.
Preparation of the present invention is the medicament of being made by the material medicine of following weight proportioning: root of kudzu vine 5-15 root of Chinese trichosanthes 5-15 rhizoma atractylodis 5-15 radix scrophulariae 5-15 gives birth to Radix Astragali 5-15 Chinese yam 5-15 gypsum 30-90 Chinese cassia tree 3-10 RADIX ACONITILATERALIS PREPARATA 3-10 Ramulus euonymi 15-45 ground beetle 5-15 parasitic loranthus 5-15 silk cocoon 20-60 stir-baked SQUAMA MANITIS 5-15 leech 5-15 dragon's blood 5-15 chinaroot greenbrier 15-45 wind-weed 5-15 gynostemma pentaphylla 15-45 dried rhizome of rehmannia 5-15 5-15 tuber of dwarf lilyturf radix paeoniae rubrathe 5-15 root bark of Chinese wolf-berry 5-15 rhubarb 5-15
The preferred weight composition of raw materials of preparation of the present invention (consumption is weight portion) ratio range is: root of kudzu vine 10-15 root of Chinese trichosanthes 10-15 rhizoma atractylodis 10-15 radix scrophulariae 10-15 gives birth to Radix Astragali 10-15 Chinese yam 10-15 gypsum 45-90 Chinese cassia tree 5-10 RADIX ACONITILATERALIS PREPARATA 5-10 Ramulus euonymi 30-45 ground beetle 10-15 parasitic loranthus 10-15 silk cocoon 40-60 stir-baked SQUAMA MANITIS 10-15 leech 10-15 dragon's blood 10-15 chinaroot greenbrier 30-45 wind-weed 10-15 gynostemma pentaphylla 30-45 dried rhizome of rehmannia 10-15 10-15 tuber of dwarf lilyturf radix paeoniae rubrathe 10-15 root bark of Chinese wolf-berry 10-15 rhubarb 10-15
The optimum feed stock prescription of preparation of the present invention (consumption is a weight portion) proportioning is: Radix Puerariae 10 Radix Trichosanthis 10 Rhizoma Atractylodis 10 Radix Scrophulariaes 10 Radix Astragali 10 Rhizoma Dioscoreaes 10 Gypsum Fibrosum 45 Cortex Cinnamomis 5 RADIX ACONITILATERALIS PREPARATA 5 Ramulus Euonymis 30 Eupolyphaga Seu Steleophagas 10 Herba Taxillis 10 Bombyx bombycis 40 stir-baked SQUAMA MANITISs 10 Hirudos 10 Sanguis Draxonis 10 Rhizoma Smilacis Chinensiss 30 Rhizoma Anemarrhenaes 10 Herb Gynostemmae Pentaphylli 30 Radix Rehmanniae 10 Radix Paeoniae Rubra, 10 Cortex Lycii, 10 Radix Ophiopogonis 10 Radix et Rhizoma Rhei (processed) 10
The preparation method that above-mentioned described each component is made preparation of the present invention is:
With the medicine in the composition of raw materials (except that Gypsum Fibrosum) with drying after the flushing with clean water, get Radix Puerariae,
Radix Trichosanthis, Rhizoma Atractylodis, Radix Scrophulariae, Radix Astragali, Rhizoma Dioscoreae, Cortex Cinnamomi, RADIX ACONITILATERALIS PREPARATA, Eupolyphaga Seu Steleophaga,
Herba Taxilli, stir-baked SQUAMA MANITIS, Hirudo, Sanguis Draxonis, the Rhizoma Anemarrhenae, the Radix Rehmanniae, Radix Ophiopogonis, Radix Paeoniae Rubra, bone
Skin, Radix et Rhizoma Rhei (processed), processing powder are broken into 120 order fineness powders;
2. get Gypsum Fibrosum, Bombyx bombycis adds 3 liters of calculating of water by every kilogram, decocts 30 minutes, taking liquid stays
Deposit;
3. get Ramulus Euonymi, Rhizoma Smilacis Chinensis, Herb Gynostemmae Pentaphylli and decoct 30 with the decoction liquor of above-mentioned Gypsum Fibrosum, Bombyx bombycis is common
Taking liquid is retained after minute;
4. get Chinese medicinal powder that operation 1 makes and be mixed and made into water pill with the decoction liquor of operation 3 Chinese medicines
Agent behind the drying and sterilizing, makes pill, is called glycosuria and fries in shallow oil pill.
Behind the above-mentioned drying and sterilizing, also can make said dosage form on powder, tablet or any pharmaceutics.
Instructions of taking: every day 3 times, each 6 grams generally need be taken medicine more than 3 months continuously.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1. the present invention selects that natural moving to plant medical material be raw material for use; Each component meets tcm theory, meets the pharmaceutical control law regulation.The present invention uses combination that medicine is executed and controls, and is used for the treatment of type 2 diabetes mellitus, and is nontoxic to human body.
2. the present invention can blood glucose steady in a long-term.According to Diabetes mellitus--chronic lifelong participation, its treatment is crucial must blood glucose steady in a long-term, and emphasis of the present invention promptly stablize blood glucose, and its effect is slowly lasting, overcomes the Western medicine i.e. effect of taking medicine, the outbreak phenomenon repeatedly that drug withdrawal blood glucose rises again.
3. the present invention can prevent and treat the complication of diabetes.Strengthen the beta Cell of islet function, the antagonism insulin resistant improves blood environment, removes harmful substance, makes the rare balance of blood, and microcirculation is unimpeded, reduces glycolated hemoglobin, thereby effectively prevents and treats complication such as the heart, brain, kidney, eye, blood vessel, nerve.
4. the present invention can improve diabetes patient's " three-many-one-little " symptom and other symptom, removes harmful substance in the intestinal, makes internal organs gas unimpeded, strengthens functions of expelling toxin.
5. the present invention still can blood fat reducing, improves fat, protein metabolism effect.It is cheap (surplus every month 100 yuan), and general patient all can bear.
For showing medicine of the present invention to the treatment of diabetes effect, the present invention has carried out the clinical observation of 252 routine systems, and selects medical history, the state of an illness, age, sex and the former suitable diabetics of method 61 examples of controlling to be matched group.
Concrete scheme:
1. object and method
1.1 object
252 examples are the outpatient, male's 131 examples wherein, women's 121 examples, age 26-83 year, 64.2 ± 7.8 years old mean age.Inclusion criteria: according to the standard of WHO1985 formulation, and with reference to the authoritative research method of DCCT and UKPDS two big worlds.
1.2 administrated method
Take the glycosuria of making the court and fry in shallow oil pill, every day 3 times, each 6 grams generally need be taken medicine more than 3 months continuously.
1.3 observational technique
Clinical symptoms: observe xerostomia, polydipsia, polyphagia, polyuria, become thin, lassitude and weak, constipation with dry stool, diarrhoea, tongue fur pulse condition etc.
Complication: observe myocardial ischemia, arrhythmia, cataract and retinopathy, cerebral blood supply insufficiency and cerebral infarction, nephropathy, gastroparalysis, foot gangrene, diabetes bulla, multiple furuncle and phyma, intractable skin pruritus, peripheral neuritis, sexual impotence etc.
Biochemical analysis: according to general international standard, adopt short-cut method, measure on an empty stomach and post-prandial glycemia, glucose in urine, partly patient glycolated hemoglobin and insulin function are measured.For a clinical simple and practical scheme and the China's national situation of providing is provided, promptly most of rural area diabetics is limited by objective condition, so the biochemical analysis aspect still is weak, remains progressively perfect.
1.4 observation of curative effect
Clinical symptoms: produce effects--symptom all disappears.Effectively--symptom disappears substantially.
Invalid--symptom does not have change.
Blood glucose is observed: produce effects--glucostasis is in good level.Effectively--glycemic control exists
General state or blood glucose decline scope are more than 5mmol/L.Invalid--blood glucose continues
Raise.
2. result
2.1 the improvement of overall clinical symptoms
The overall disease efficacy analysis of table 1
| Total case | Produce effects | Effectively | Invalid | Effectively total | |
| Case load | 252 | ?199 | 47 | 6 | 246 |
| Percentage rate (%) | 100 | ?78.97 | 18.65 | 2.38 | 97.62 |
2.2 individual event disease curative effect
Table 2 individual event disease efficacy analysis
| Disease | Total routine number | Produce effects | Effectively | Invalid | Total effectively (%) |
| Xerostomia | 247 | ?198 | ?44 | ?5 | ?242(97.98) |
| Polydipsia | 183 | ?161 | ?22 | ?0 | ?183(100) |
| Polyphagia | 223 | ?167 | ?53 | ?3 | ?220(98.65) |
| Polyuria | 121 | ?109 | ?10 | ?2 | ?119(98.35) |
| Become thin | 214 | ?168 | ?43 | ?3 | ?211(98.56) |
| Constipation with dry stool | 146 | ?124 | ?22 | ?0 | ?146(100) |
| Diarrhoea | 17 | ?14 | ?3 | ?0 | ?17(100) |
| Constipation diarrhoea alternately | 6 | ?3 | ?3 | ?0 | ?6(100) |
| Weak | 204 | ?158 | ?43 | ?3 | ?201(98.53) |
2.3 blood sugar test situation
The analysis of table 3 blood glucose condition
| Total case | Produce effects | Effectively | Invalid | Effectively total | |
| Case load | 252 | ?208 | ?40 | ?4 | ?248 |
| Percentage rate (%) | 100 | ?82.54 | ?15.87 | ?1.59 | ?98.41 |
2.4 complication is improved situation, 252 routine patients have complication 213 people's number of times, total effective 186
People's number of times, total effective rate 87.32%, prove glycosuria fry in shallow oil pill improve aspect the complication effective.
Table 4 diabetic complication improves status analysis
2.5 matched group relatively
| Complication | Case load | Alleviate | Disappear | Do not have and change | Total significant figure (%) |
| Cataract | 35 | ?23 | ?0 | ?12 | ?23.(65.71) |
| Retinopathy | 8 | ?4 | ?1 | ?3 | ?5(62.5) |
| Cerebral ischemia | 9 | ?9 | ?0 | ?0 | ?9(100) |
| Cerebral infarction | 6 | ?5 | ?0 | ?1 | ?5(83.33) |
| Myocardial ischemia | 26 | ?16 | ?6 | ?4 | ?22(84.62) |
| Arrhythmia | 24 | ?11 | ?9 | ?4 | ?20(83.33) |
| Nephropathy | 4 | ?3 | ?0 | ?1 | ?3(75) |
| Gastroparalysis | 18 | ?0 | ?18 | ?0 | ?18(100) |
| Foot gangrene | 5 | ?0 | ?5 | ?0 | ?5(100) |
| The diabetes bulla | 12 | ?0 | ?12 | ?0 | ?12(100) |
| Multiple furuncle and phyma | 9 | ?0 | ?9 | ?0 | ?9(100) |
| Skin pruritus | 32 | ?8 | ?24 | ?0 | ?32(100) |
| Peripheral neuritis | 17 | ?11 | ?4 | ?2 | ?15(94.12) |
| Sexual impotence | 8 | ?4 | ?2 | ?2 | ?6(75) |
If matched group and the treatment of this group are observed, matched group adopts Chinese medicine and therapies such as Western medicine or diet motion from the outpatient service random collecting.The blood glucose heave amplitude that need to prove matched group is big, and complication is more Zao and weigh than this group.
This group of table 5 compares with the matched group curative effect
2.6 untoward reaction
| Case load | Produce effects (%) | Effectively (%) | Invalid (%) | Total effectively (%) | |
| Glycosuria is fried in shallow oil the ball group | 252 | ?208(82.54) | 40(15.87) | 4(1.59) | 248(98.41) |
| Matched group | 61 | ?18.(29.51) | 31(50.82) | 12(19.67) | 49(80.32) |
252 examples are fried in shallow oil in the pill therapeutic process with glycosuria, and 6 examples of suffering from diarrhoea (account for 2.38%), behind symptomatic treatment, disappears; Abdominal distention 12 examples (accounting for 4.7%), untreated, 1-2 spontaneous remission after week does not influence treatment.
The specific embodiment
Embodiment 1:
Press following proportioning weighting raw materials thing (kilogram): Radix Puerariae 10 Radix Trichosanthis 10 Rhizoma Atractylodis 10 Radix Scrophulariaes 10 Radix Astragali 10 Rhizoma Dioscoreaes 10 Gypsum Fibrosum 45 Cortex Cinnamomis 5 RADIX ACONITILATERALIS PREPARATA 5 Ramulus Euonymis 30 Eupolyphaga Seu Steleophagas 10 Herba Taxillis 10 Bombyx bombycis 40 stir-baked SQUAMA MANITISs 10 Hirudos 10 Sanguis Draxonis 10 Rhizoma Smilacis Chinensiss 30 Rhizoma Anemarrhenaes 10 Herb Gynostemmae Pentaphylli 30 Radix Rehmanniae 10 Radix Paeoniae Rubra, 10 Cortex Lycii, 10 Radix Ophiopogonis 10 Radix et Rhizoma Rhei (processed) 10
With said medicine (except that Gypsum Fibrosum) with drying after the flushing with clean water; Get Radix Puerariae, Radix Trichosanthis, Rhizoma Atractylodis, Radix Scrophulariae, Radix Astragali, Rhizoma Dioscoreae, Cortex Cinnamomi, RADIX ACONITILATERALIS PREPARATA, Eupolyphaga Seu Steleophaga, Herba Taxilli, stir-baked SQUAMA MANITIS, Hirudo, Sanguis Draxonis, the Rhizoma Anemarrhenae, the Radix Rehmanniae, Radix Ophiopogonis, Radix Paeoniae Rubra, Cortex Lycii, Radix et Rhizoma Rhei (processed) processing powder and be broken into 120 order fineness powder; Get Gypsum Fibrosum, Bombyx bombycis, add 255 liters in water, decocted 30 minutes, taking liquid is retained; Getting the common taking liquid that decocts after 30 minutes of decoction liquor that Ramulus Euonymi, Rhizoma Smilacis Chinensis, Herb Gynostemmae Pentaphylli use retains; Get Chinese medicinal powder and be mixed and made into the water pill agent with the decoction liquor of Chinese medicine, the about 5mm of pill diameter, behind the drying and sterilizing glycosuria fry in shallow oil pill.
Embodiment 2:
Press following proportioning weighting raw materials thing (kilogram): Radix Puerariae 5 Radix Trichosanthis 5 Rhizoma Atractylodis 5 Radix Scrophulariaes 5 Radix Astragali 5 Rhizoma Dioscoreaes 5 Gypsum Fibrosum 30 Cortex Cinnamomis 3 RADIX ACONITILATERALIS PREPARATA 3 Ramulus Euonymis 15 Eupolyphaga Seu Steleophagas 5 Herba Taxillis 5 Bombyx bombycis 20 stir-baked SQUAMA MANITISs 5 Hirudos 5 Sanguis Draxonis 5 Rhizoma Smilacis Chinensiss 15 Rhizoma Anemarrhenaes 5 Herb Gynostemmae Pentaphylli 15 Radix Rehmanniae 5 Radix Paeoniae Rubra, 5 Cortex Lycii, 5 Radix Ophiopogonis 5 Radix et Rhizoma Rhei (processed) 5
With said medicine (except that Gypsum Fibrosum) with drying after the flushing with clean water; Get Radix Puerariae, Radix Trichosanthis, Rhizoma Atractylodis, Radix Scrophulariae, Radix Astragali, Rhizoma Dioscoreae, Cortex Cinnamomi, RADIX ACONITILATERALIS PREPARATA, Eupolyphaga Seu Steleophaga, Herba Taxilli, stir-baked SQUAMA MANITIS, Hirudo, Sanguis Draxonis, the Rhizoma Anemarrhenae, the Radix Rehmanniae, Radix Ophiopogonis, Cortex Lycii, Radix et Rhizoma Rhei (processed) processing powder and be broken into 120 order fineness powder; Get Gypsum Fibrosum, Bombyx bombycis, add 150 liters in water, decocted 30 minutes, taking liquid is retained; Getting the common taking liquid that decocts after 30 minutes of decoction liquor that Ramulus Euonymi, Rhizoma Smilacis Chinensis, Herb Gynostemmae Pentaphylli use retains; Get Chinese medicinal powder and be mixed and made into the water pill agent with the decoction liquor of Chinese medicine, the about 5mm of pill diameter, behind the drying and sterilizing glycosuria fry in shallow oil pill.
Embodiment 3: Radix Puerariae 15 Radix Trichosanthis 15 Rhizoma Atractylodis 15 Radix Scrophulariaes 15 Radix Astragali 15 Rhizoma Dioscoreaes 15 Gypsum Fibrosum 90 Cortex Cinnamomis 10 RADIX ACONITILATERALIS PREPARATA 10 Ramulus Euonymis 45 Eupolyphaga Seu Steleophagas 15 Herba Taxillis 15 Bombyx bombycis 60 stir-baked SQUAMA MANITISs 15 Hirudos 15 Sanguis Draxonis 15 Rhizoma Smilacis Chinensiss 45 Rhizoma Anemarrhenaes 15 Herb Gynostemmae Pentaphylli 45 Radix Rehmanniae 15 Radix Paeoniae Rubra, 15 Cortex Lycii, 15 Radix Ophiopogonis 15 Radix et Rhizoma Rhei (processed) 15
With said medicine (except that Gypsum Fibrosum) with drying after the flushing with clean water; Get Radix Puerariae, Radix Trichosanthis, Rhizoma Atractylodis, Radix Scrophulariae, Radix Astragali, Rhizoma Dioscoreae, Cortex Cinnamomi, RADIX ACONITILATERALIS PREPARATA, Eupolyphaga Seu Steleophaga, Herba Taxilli, stir-baked SQUAMA MANITIS, Hirudo, Sanguis Draxonis, the Rhizoma Anemarrhenae, the Radix Rehmanniae, Radix Ophiopogonis, Radix Paeoniae Rubra, Cortex Lycii, Radix et Rhizoma Rhei (processed) processing powder and be broken into 120 order fineness powder; Get Gypsum Fibrosum, Bombyx bombycis, add 450 liters in water.Decocted 30 minutes, taking liquid is retained; Getting the common taking liquid that decocts after 30 minutes of decoction liquor that Ramulus Euonymi, Rhizoma Smilacis Chinensis, Herb Gynostemmae Pentaphylli use retains; Get Chinese medicinal powder and be mixed and made into the water pill agent with the decoction liquor of Chinese medicine, the about 5mm of pill diameter, behind the drying and sterilizing glycosuria fry in shallow oil pill.Model case:
Case one: Huang Shujuan, woman, 76 years old, diabetes 5 years, because of blood glucose continues not fall at certain hospital's department of endocrinology hospitalization, leaving hospital, back insulin injection 24u/ day, three usefulness were surplus, because of local skin allergy is sought treatment by Chinese herbs, fry in shallow oil oral each 6 grams of pill with glycosuria, every day three times, and gradual slow subtracts insulin dosage, inactive insulin after treatment in 3 months, follow up a case by regular visits to 5 years blood glucose and be stabilized in normal level always, glucose in urine continues negative, and overall health of patients is good.
Case two: Zhu Weiping, the woman, 56 years old, because of the polydipsia prescription on individual diagnosis of becoming thin, 5 post-prandial glycemia are all about 15.2mmol/L, do not obey Western medicine, fry in shallow oil pill after January, post-prandial glycemia 7.6mmol/L through the clothes glycosuria, after take glycosuria for a long time and fry in shallow oil pill, followed up a case by regular visits to 3 years, blood glucose is stabilized in normal level always, and no complication takes place.
Claims (6)
1, a kind of Chinese traditional compound medicine for the treatment of type 2 diabetes mellitus is characterized in that it is the medicament of being made by the following raw materials by weight proportions thing:
Radix Puerariae 5-15 Radix Trichosanthis 5-15 Rhizoma Atractylodis 5-15 Radix Scrophulariae 5-15 Radix Astragali 5-15
Rhizoma Dioscoreae 5-15 Gypsum Fibrosum 30-90 Cortex Cinnamomi 3-10 RADIX ACONITILATERALIS PREPARATA 3-10 Ramulus Euonymi 15-45
Eupolyphaga Seu Steleophaga 5-15 Herba Taxilli 5-15 Bombyx bombycis 20-60 stir-baked SQUAMA MANITIS 5-15 Hirudo 5-15
Sanguis Draxonis 5-15 Rhizoma Smilacis Chinensis 15-45 Rhizoma Anemarrhenae 5-15 Herb Gynostemmae Pentaphylli 15-45 Radix Rehmanniae 5-15
Radix Ophiopogonis 5-15 Radix Paeoniae Rubra 5-15 Cortex Lycii 5-15 Radix et Rhizoma Rhei (processed) 5-15
2,, it is characterized in that preferred feedstock weight proportion scope of the present invention is according to the described a kind of Chinese traditional compound medicine for the treatment of type 2 diabetes mellitus of claim 1:
Radix Puerariae 10-15 Radix Trichosanthis 10-15 Rhizoma Atractylodis 10-15 Radix Scrophulariae 10-15 Radix Astragali 10-15
Rhizoma Dioscoreae 10-15 Gypsum Fibrosum 45-90 Cortex Cinnamomi 5-10 RADIX ACONITILATERALIS PREPARATA 5-10 Ramulus Euonymi 30-45
Eupolyphaga Seu Steleophaga 10-15 Herba Taxilli 10-15 Bombyx bombycis 40-60 stir-baked SQUAMA MANITIS 10-15 Hirudo 10-15
Sanguis Draxonis 10-15 Rhizoma Smilacis Chinensis 30-45 Rhizoma Anemarrhenae 10-15 Herb Gynostemmae Pentaphylli 30-45 Radix Rehmanniae 10-15
Radix Ophiopogonis 10-15 Radix Paeoniae Rubra 10-15 Cortex Lycii 10-15 Radix et Rhizoma Rhei (processed) 10-15
3,, it is characterized in that optimum feed stock weight proportion of the present invention is according to the described a kind of Chinese traditional compound medicine for the treatment of type 2 diabetes mellitus of claim 1:
Radix Puerariae 10 Radix Trichosanthis 10 Rhizoma Atractylodis 10 Radix Scrophulariaes 10 Radix Astragali 10 Rhizoma Dioscoreaes 10
Gypsum Fibrosum 45 Cortex Cinnamomis 5 RADIX ACONITILATERALIS PREPARATA 5 Ramulus Euonymis 30 Eupolyphaga Seu Steleophagas 10 Herba Taxillis 10
Bombyx bombycis 40 stir-baked SQUAMA MANITISs 10 Hirudos 10 Sanguis Draxonis 10 Rhizoma Smilacis Chinensiss 30 Rhizoma Anemarrhenaes 10
Herb Gynostemmae Pentaphylli 30 Radix Rehmanniae 10 Radix Paeoniae Rubra, 10 Cortex Lycii, 10 Radix Ophiopogonis 10 Radix et Rhizoma Rhei (processed) 10
4,, it is characterized in that described medicament is a said dosage form on any pharmaceutics according to claim 1 or 2 or 3 described a kind of Chinese traditional compound medicines for the treatment of type 2 diabetes mellitus.
5, according to the described a kind of Chinese traditional compound medicine for the treatment of type 2 diabetes mellitus of claim 4, it is characterized in that described medicament is a pill.
6, the described a kind of preparation method for the treatment of the Chinese traditional compound medicine of type 2 diabetes mellitus of claim 5 is characterized in that:
1) with the medicine in the composition of raw materials, except that Gypsum Fibrosum, with drying after the flushing with clean water, get Radix Puerariae, Radix Trichosanthis, Rhizoma Atractylodis, Radix Scrophulariae, Radix Astragali, Rhizoma Dioscoreae, Cortex Cinnamomi, RADIX ACONITILATERALIS PREPARATA, Eupolyphaga Seu Steleophaga, Herba Taxilli, stir-baked SQUAMA MANITIS, Hirudo, Sanguis Draxonis, the Rhizoma Anemarrhenae, the Radix Rehmanniae, Radix Ophiopogonis, Radix Paeoniae Rubra, Cortex Lycii, Radix et Rhizoma Rhei (processed), processing powder is broken into 120 order fineness powders;
2) get Gypsum Fibrosum, Bombyx bombycis adds 3 liters of calculating of water by every kilogram, decocts 30 minutes, taking liquid is retained;
3) getting Ramulus Euonymi, Rhizoma Smilacis Chinensis, Herb Gynostemmae Pentaphylli retains with the common taking liquid that decocts after 30 minutes of the decoction liquor of above-mentioned Gypsum Fibrosum, Bombyx bombycis;
4) get operation 1) Chinese medicinal powder made is with operation 3) decoction liquor of Chinese medicine is mixed and made into the water pill agent, behind the drying and sterilizing, makes pill.
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| CN100364601C (en) * | 2004-10-10 | 2008-01-30 | 魏群利 | Chinese traditional medicine composition for treating diabetic nephropathy |
| CN100379441C (en) * | 2005-12-20 | 2008-04-09 | 湖南九典制药有限公司 | Sugar downbearing network vessel freeing Chinese medicinal preparation |
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| CN101623389B (en) * | 2009-07-30 | 2011-05-18 | 南京中医药大学 | Drug for curing diabetes and preparation method thereof |
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| CN104013915A (en) * | 2014-06-19 | 2014-09-03 | 张晓利 | Traditional Chinese medicine for treating glycuresis and preparation method thereof |
| CN104382022A (en) * | 2014-11-03 | 2015-03-04 | 安徽含眉生态茶叶有限公司 | Health drink containing gynostemma pentaphyllum |
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