CN101890145B - Medicament for treating diabetes and preparation thereof - Google Patents

Medicament for treating diabetes and preparation thereof Download PDF

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CN101890145B
CN101890145B CN2010102329551A CN201010232955A CN101890145B CN 101890145 B CN101890145 B CN 101890145B CN 2010102329551 A CN2010102329551 A CN 2010102329551A CN 201010232955 A CN201010232955 A CN 201010232955A CN 101890145 B CN101890145 B CN 101890145B
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radix
medicine
root
diabetes
medicament
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CN101890145A (en
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杜爱芝
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Abstract

The invention discloses a medicament for treating diabetes and a preparation method thereof. In the invention, bupleurum, turmeric root tuber, immature bitter orange, scrophularia, dwarf lilyturf tuber, heterophylly falsestarwort root, honeysuckle, dahurian patrinia herb, spreading hedyotis herb, salvia miltiorrhiza bunge, finger citron, yam, chicken's gizzard-membrane, pollen, root of rehmannia,liquoric root and other traditional Chinese herbal medicines are used as raw materials; the mixed raw materials are decocted over a slow fire repeatedly; and the decoctions are mixed and prepared into oral liquid. The medicament can offer comprehensive treatment by soothing liver, regulating vital energy, nourishing yin and yang, inviting body fluid, promoting blood circulation, removing blood stasis, clearing heat, detoxicating, tonifying spleen and the like, and can reduce blood sugar, improve glycometabolism and balance the functions of all organs effectively to achieve a quick, stable andlight-side effect blood sugar reducing effect.

Description

A kind of medicine for the treatment of diabetes and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of diabetes, particularly a kind of is the medicine of the treatment diabetes of feedstock production with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Background technology
Diabetes are a kind of common metabolic diseases, divide constitutional and Secondary cases.The former has genetic predisposition by great majority, and basic pathology physiology is absolute and relative, and hypoinsulinism and pancreas rise the plain active caused metabolism disorder that raises of sugar.It is characterized by hyperglycemia, urine disease, glucose tolerance attenuating and insulin discharges unusual.Clinical in early days can be asymptomatic, to the symptom phase polydipsia, polyphagia, polyuria are just arranged, the symptom such as weak of becoming thin.The easy concurrent cardiovascular and cerebrovascular disease of patients on long-term, diseases such as kidney, eye, nerve, ketoacidosis can take place in severe patient.
In recent years, along with the traditional Chinese medical science deepening continuously to the sick understanding of sugar, people begin to pay attention to the effect of the pyretic toxicity deficiency of YIN in diabetes, Chinese medicine has the viewpoint of " the evil poison of containing meaning ", the pyretic toxicity of interior life often betides on the miscellaneous diseases caused by endogenous pathogens basis, because people's living standard improves constantly the improvement of life style and dietary structure, modern's mental pressure is big in addition, causes irritability stasis, the living heat of stagnated QI transforming into fire more.Smoking, drink, polyphagia, delicious food, savoury, all give birth to pyretic toxicity or expectorant and become silted up and accumulate and pathomechanism that the silt pyretic toxicity is mingled with mutually.
The many Western medicine of current treatment diabetes all have in various degree side effect such as damage to gastrointestinal tract and Liver and kidney.The application of insulin reaches in daily life also many inconvenience when going out.I observe and explore, and according to the pathogenesis of diabetes in the traditional Chinese medical science, reinforce natural Chinese medicinal herb, with comprehensive treatments such as liver-smoothing, qi-regulating, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, the YIN nourishing of establishing the yang function, spleen invigorating, have obtained curative effect preferably.
Summary of the invention
The medicine that the purpose of this invention is to provide a kind of effective treatment diabetes, this medicine is taking convenience not only, and prescription is unique, good effect, side effect is little, can remove patient's misery.
The preparation method that this medicine is provided is an another object of the present invention.
Medicine of the present invention is to be made by the raw material of following mass ratio:
Figure GSB00000546680400021
Preparation method of the present invention is:
The clear water that Radix Bupleuri, Radix Curcumae, Fructus Aurantii Immaturus, Radix Scrophulariae, Radix Ophiopogonis, Radix Pseudostellariae, Flos Lonicerae, Herba Patriniae, Herba Hedyotidis Diffusae, Radix Salviae Miltiorrhizae, Fructus Citri Sarcodactylis, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, pollen, the Radix Rehmanniae, Radix Glycyrrhizae is added the 80-100 weight portion, 0.5-1.5 at a simmer hour, fry in shallow oil repeatedly three times, three filtrates are mixed, every 500ml is one bag, makes oral liquid and is finished product.
Usage: one bag of every day, (medicine) being taken before meal is used sooner or later.
The pharmacology of each medicine of the present invention is:
The Radix Bupleuri liver-smoothing, qi-regulating; Radix Curcumae promoting QI circulation for relieving depression, stasis-dispelling and pain-killing, promoting the circulation of QI and reducing phlegm, can make body fluid demutation in menstrual period; Fructus Aurantii Immaturus, Fructus Citri Sarcodactylis, Rhizoma Dioscoreae strengthening the spleen to promote digestion; Radix Scrophulariae, pollen for tonifying-Yin promote the production of body fluid; Radix Ophiopogonis, Radix Pseudostellariae, Radix Rehmanniae yin nourishing, the lung moistening and production of body fluid promoting; Flos Lonicerae, Herba Patriniae, Herba Hedyotidis Diffusae heat-clearing and toxic substances removing; Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, inhibition platelet aggregation improve blood viscosity; Radix Glycyrrhizae and medicine detoxifcation.
Through Drug therapy 162 examples of the present invention, wherein male 101 examples, women 61 examples, age 49-67 year, 54.2 years old mean age, the course of disease 1 thoughtful 10 years, average 6.2 years.Through taking this medicine, polydipsia, polyphagia, polyuria, the Signs complete obiteration such as weak of becoming thin, blood glucose is normal.Total effective rate 96.4%.
Beneficial effect
This medicine is by liver-smoothing, qi-regulating, YIN nourishing establish the yang function promote the production of body fluid, Comprehensive Treatments such as blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing and spleen invigorating, effectively blood sugar lowering improves carbohydrate metabolism, makes each internal organs function equilibrium of human body, thereby reaches fast, stablizes, the extremely light hypoglycemic effect of side effect.
The specific embodiment
The invention will be further described below in conjunction with embodiment, but do not constitute any limitation of the invention.
Prepare raw material according to following weight:
Get Radix Bupleuri 10kg, Radix Curcumae 10kg, Fructus Aurantii Immaturus 10kg, Radix Scrophulariae 10kg, Radix Ophiopogonis 10kg, Radix Pseudostellariae 15kg, Flos Lonicerae 10kg, Herba Patriniae 20kg, Herba Hedyotidis Diffusae 20kg, Radix Salviae Miltiorrhizae 20kg, Fructus Citri Sarcodactylis 10kg, Rhizoma Dioscoreae 15kg, Endothelium Corneum Gigeriae Galli 10kg, pollen 20kg, Radix Rehmanniae 20kg, Radix Glycyrrhizae 3kg.
With the clear water of above-mentioned all medicine adding 800kg, 0.5-1.5 at a simmer hour, fry in shallow oil repeatedly three times, three filtrates are mixed, every 500ml is one bag, makes oral liquid, encapsulation cold preservation is finished product.
Usage: one bag of every day, (medicine) being taken before meal is used sooner or later.
Embodiment 1: king elder generation, man, 60 years old, Changzi County Qing Feng people from village, polydipsia, polyphagia polyuria.Fell ill 3 years and accompany violently dizzy, can not walk 3 days.Live Changzhi and Ji hospitalize on August 10th, 2009.Be diagnosed as type ii diabetes companion cerebellum large tracts of land infarction after being admitted to hospital.While in hospital gives subcutaneous injection insulinize, and effect is not good enough, and fasting glucose fluctuates about 10g/l always, post-prandial glycemia 15g/l.After leaving hospital, add Chinese herbal medicine after one week, blood glucose is promptly reduced to normal range, and the mental status is good.In 5 weeks of after treatment, above-mentioned symptom disappears fully, and is existing alive.Blood glucose maintains normal range always, and little cerebral infarction also returns to one's perfect health, and Ambulatory Activity is normal.
Embodiment 2: Bao Zhengxiang, woman, 60 years old, Changzi County Dongguo people from village.In calendar year 2001 because of polydipsia, polyphagia, polyuria, thin, the extremity tip numbness of body.Examine in the People's Hospital, Changzi County and to be type ii diabetes, first oral western medicine treatment is not good enough.After add Chinese herbal medicine, respond well.1 week, back blood glucose was reduced to normally, and again 4 weeks of after treatment, above-mentioned uncomfortable Signs complete obiteration shows body and is good for, and can be competent at all normal housework.
Embodiment 3: Bao Zhengtang, man, 56 years old, Changzi County Bao Zhuan people from village.Be diagnosed as type ii diabetes (Changzhi City peace hospital and the People's Hospital, Changzi County) in March, 2002, first oral western medicine treatment 1 month, effect is not good enough, and the oral Chinese herbal medicine in back is respond well.1 all blood glucose is reduced to normally, the complete obiteration of diabetes Signs, and existing body is strong, can be competent at all farm work.
Embodiment 4: Wang Junde, man, 48 years old, Changzi County Jiao Li people from village.Because of thin weak, the numb limbs and tense tendons of polydipsia, polyphagia, polyuria, body half a year.Go to a doctor in the People's Hospital, Changzi County on May 10th, 2010, sugar (on an empty stomach) 33.5g/l has a blood test, received patient's hospitalization at that time, I refuse to be in hospital, and outpatient service gave western medicine 3 days, and effect is not good enough, after adding Chinese herbal medicine, fasting glucose is reduced to 11.5g/l, and polydipsia, polyphagia, polyuria are obviously alleviated, and is existing still in treatment is followed up a case by regular visits to.
Case history statistics: all cases all derive from the calendar year 2001 type ii diabetes collected year May of February-2010 and diabetes disease that takes place frequently, and amount to 162 examples, wherein male 101 examples, women 61 examples, age 49-67 year, 54.2 years old mean age, the course of disease 1 thoughtful 10 years, average 6.2 years.Above-mentioned case all meets country's AD/WHO diabetes diagnosis standard in 1997.Now be divided into 2 groups at random, that is: (the treatment group adds Chinese herbal medicine for treatment group and matched group; Matched group list western medicine) criterion of cure, polydipsia, polyphagia, polyuria, the Signs complete obiteration such as weak of becoming thin, blood glucose is normal.
Two groups of diabetes 2 all curative effect comparision tables
Figure GSB00000546680400041
By the treatment of above synopsis, add oral Chinese herbal medicine after, curative effect and untoward reaction all obviously are better than the western medicine group.After above-mentioned case all treated for two weeks, after treatment 2 again---and in 3 weeks, blood glucose and clinical symptoms all maintain normal range, and relapse rate is less.

Claims (2)

1. medicine for the treatment of diabetes, it is characterized in that: this medicine is to be made by the raw material of following mass ratio:
Figure FSB00000546680300011
2. according to the preparation method of the medicine of the described treatment diabetes of claim 1, it is characterized in that: this medicine is the clear water that Radix Bupleuri, Radix Curcumae, Fructus Aurantii Immaturus, Radix Scrophulariae, Radix Ophiopogonis, Radix Pseudostellariae, Flos Lonicerae, Herba Patriniae, Herba Hedyotidis Diffusae, Radix Salviae Miltiorrhizae, Fructus Citri Sarcodactylis, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, pollen, the Radix Rehmanniae, Radix Glycyrrhizae is added the 80-100 weight portion, 0.5-1.5 at a simmer hour, fry in shallow oil repeatedly three times, three filtrates are mixed, every 500ml is one bag, makes oral liquid and is finished product.
CN2010102329551A 2010-07-19 2010-07-19 Medicament for treating diabetes and preparation thereof Expired - Fee Related CN101890145B (en)

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CN104225377A (en) * 2014-08-23 2014-12-24 蒋保珍 Traditional Chinese medicine composition for treating liver-qi stasis type diabetes and application of traditional Chinese medicine composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1376495A (en) * 2002-01-31 2002-10-30 刘惠生 Chinese medicine for treating diabetes and its complication
CN1634174A (en) * 2003-12-29 2005-07-06 林明兴 Chinese traditional medicine for treating diabetes
CN101095913A (en) * 2007-07-05 2008-01-02 北京艺信堂医药研究所 Chinese medicine preparation for treating diabetes cholecystitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1376495A (en) * 2002-01-31 2002-10-30 刘惠生 Chinese medicine for treating diabetes and its complication
CN1634174A (en) * 2003-12-29 2005-07-06 林明兴 Chinese traditional medicine for treating diabetes
CN101095913A (en) * 2007-07-05 2008-01-02 北京艺信堂医药研究所 Chinese medicine preparation for treating diabetes cholecystitis

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