CN109674705A

CN109674705A - A kind of skin care item for improveing skin condition

Info

Publication number: CN109674705A
Application number: CN201910121036.8A
Authority: CN
Inventors: 王琳琳; 王丽丽
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-02-19
Filing date: 2019-02-19
Publication date: 2019-04-26

Abstract

The present invention provides a kind of skin care item for improveing skin condition, include component as follows by mass percentage: skin cream matrix is 25%~45%, kudzu root extract 10%, oligopeptides -1 are 2%, remaining is deionized water, the skin care item are made of oligopeptides -1 and Radix Puerariae, are had the function of proliferation, are repaired, is anti-ageing；It is not simple moisturizing or supplement hormone, but the hormonal parent of activation -- body of gland, the hormone for allowing glandular secretion that human body is suitble to need, excite itself self-regeneration and cosmetology function, product is pure natural simultaneously, to body fanout free region, it is suitble to various skin quality, the present invention is without ethics defect and safe and feasible.

Description

A kind of skin care item for improveing skin condition

Technical field

The present invention relates to beauty and skin care field more particularly to a kind of skin care item for improveing skin condition.

Background technique

Skin care has become a Men Xuewen in the modern times, and people are no longer blindly gone shopping by skin problem puzzlement and buy variousization Cosmetic is tried, but outputs prescription by dermatologist, provides targetedly skin care suggestion.As people are to the pursuit day of health The surging high speed development with dermatology of benefit, the medicine skin care item with greater security and validity have become irresistible One trend.

Dry skin, damage or aging are a kind of common phenomenons, will be greatly reduced the quality of life of a people, even Lead to various skin diseases.Skin-protection product moisturizing breaks dry skin circulation.Although there is abundant evidence that using Mild facial cleanser and milky lotion is beneficial, but many researchs before are only limitted to the effect of single facial cleanser or milky lotion.

Summary of the invention

It is an object of the invention in view of the above shortcomings of the prior art, provide a kind of skin care for improveing skin condition Product can promote new life, reparation and the anti-aging of cell.

To achieve the above object, present invention employs following technical solutions:

The present invention provides a kind of skin care item for improveing skin condition, include component as follows by mass percentage: profit Skin frost matrix is 25%~45%, kudzu root extract 10%, oligopeptides -1 are 2%, remaining is deionized water.

Further, the skin cream matrix includes following component by mass percentage: moisturizer is 12%~20%, Emulsifier is 1%~5% and grease is 12%~20%.

Further, the moisturizer includes glycerol, propylene glycol, glycine betaine and hyaluronic acid；The emulsifier includes alkyl Glucosides, glycerin monostearate, hydrolecithin；The grease includes vaseline, olive oil, mineral oil, vitamin E oil.

Further, the kudzu root extract includes following component by mass percentage: daidzein 2%-5%, greatly Beans glucoside is 5%-10%, Puerarin is 10%-20% and Puerarin -7- xyloside is 8%-10%.

Further, the oligopeptides -1 includes following extraction step:

1) it extracts；

2) it separates；

3) in vitro culture；

4) oligopeptides -1 is separated using chromatography；

5) high performance liquid chromatography is identified.

Further, following steps are taken in the preparation of skin care item:

I 85 degree of mixings after) proportionally mixing the skin cream matrix, the kudzu root extract and deionized water, so Adjust pH value to 6~8 afterwards；

II it) is added after oligopeptides -1 mixes and obtains finished product.

The invention has the benefit that the skin care item are made of oligopeptides -1 and Radix Puerariae, there is proliferation (to promote the new of cell It is raw), repair and (repair damaged cell), the effect of anti-ageing (delaying cell aging)；Be not simple moisturizing or supplement hormone, and It is the hormonal parent of activation -- body of gland, the hormone for allowing glandular secretion that human body is suitble to need excites the self-regeneration of itself And cosmetology function, while product is pure natural, to body fanout free region, is suitble to various skin quality, and the present invention is without ethics defect and safety can Row.

Detailed description of the invention

Fig. 1 is the structural schematic diagram of oligopeptides -1；

Fig. 2 is to be not coated with the skin repair picture of the damage group of anything after 14 days；

Fig. 3 is the skin repair picture of Tu great Bao skin cream group after 14 days；

Fig. 4 is to apply the skin repair picture of the skin care item group after 14 days；

Fig. 5 is the schematic diagram of collagen expression.

Specific embodiment

In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right The present invention is further elaborated.It should be appreciated that described herein, specific examples are only used to explain the present invention, not For limiting the present invention.

A kind of skin care item for improveing skin condition, include component as follows by mass percentage: skin cream matrix is 25%~45%, kudzu root extract 10%, oligopeptides -1 such as Fig. 1 is 2%, remaining is deionized water.

Conventional skin cream matrix is improved, is added to core component oligopeptides -1 and kudzu root extract, and can be by the shield The product cut size of skin product is less than the liquid crystal state of 30nm.

The skin cream matrix includes following component by mass percentage: moisturizer is 12%~20%, emulsifier It is 12%~20% for 1%~5% and grease.

The moisturizer includes glycerol, propylene glycol, glycine betaine and hyaluronic acid；The emulsifier includes alkyl glycosides, list Tristerin, hydrolecithin；The grease includes vaseline, olive oil, mineral oil, vitamin E oil.

The kudzu root extract includes following component by mass percentage: daidzein 2%-5%, daidzin are 5%-10%, Puerarin are 10%-20% and Puerarin -7- xyloside is 8%-10%.

The oligopeptides -1 includes following extraction step:

1) it extracts；

2) it separates；

3) in vitro culture；

4) oligopeptides -1 is separated using chromatography；

5) high performance liquid chromatography is identified.

Following steps are taken in the preparation of skin care item:

II it) is added after oligopeptides -1 mixes and obtains finished product.

Embodiment one

It is heating after 25% skin cream matrix, 10% kudzu root extract and deionized water mix by mass percent It is mixed to 85 degree, then adjusts pH value to 6~8, obtain finished product after being eventually adding 2% mixing of oligopeptides -1.

Embodiment two

It is heating after 35% skin cream matrix, 10% kudzu root extract and deionized water mix by mass percent It is mixed to 85 degree, then adjusts pH value 6~8, obtain finished product after being eventually adding 2% mixing of oligopeptides -1.

Embodiment three

It is heating after 45% skin cream matrix, 10% kudzu root extract and deionized water mix by mass percent It is mixed to 85 degree, then adjusts pH value 6~8, obtain finished product after being eventually adding 2% mixing of oligopeptides -1.

Experimental method

Step 1: take 6~8 week old Female nude mices, aseptically, respectively cut on sole with scalpel about 1cm × The full thickness skin of 1cm size, defect point smear big precious skin cream and the skin care item respectively, are divided into three groups: damage group, damage+big Precious skin cream group, the damage+skin care item group.Skin repair situation is observed after two weeks.

Step 2: taking 24 week old Female nude mices, aseptically, big precious skin cream and shield are smeared ageing skin respectively Skin product are divided into three groups: normal group, big precious skin cream group, the skin care item group.Skin histology is taken to carry out western blot after a week Detection, observation collagen generate situation.

Test result

Wherein, Fig. 2 is to be not coated with the skin repair picture of the damage group of anything after 14 days；Fig. 3 is Tu great after 14 days The skin repair picture of precious skin cream group；Fig. 4 is to apply the skin repair picture of the skin care item group after 14 days.

Treatment discovery is carried out to damage mouse, skin care item treatment group mouse wound reply situation is best, followed by big treasured Skin cream group illustrates that the skin care item are more more advantageous in terms of promoting skin repair than conventional skin cream.

As shown in figure 5, A is collagen I, B is collagen II, and C Actin, D are check plot, and E is the skin care item Area, F are great Bao skin cream area.

Different treatment discoveries are carried out to mouse aging, compared to less treatment group, after the skin care item and big precious skin cream treatment Collagen is significantly promoted to express, and relatively large precious skin cream treatment group, to collagen expressing promoting after skin care item treatment It is the most significant into acting on.

Embodiments of the present invention above described embodiment only expresses, the description thereof is more specific and detailed, but can not Therefore limitations on the scope of the patent of the present invention are interpreted as.It should be pointed out that for those of ordinary skill in the art, Without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection model of the invention It encloses.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.

Claims

1. a kind of skin care item for improveing skin condition, it is characterised in that: include component as follows by mass percentage: skin cream Matrix is 25%~45%, kudzu root extract 10%, oligopeptides -1 are 2%, remaining is deionized water.

2. a kind of skin care item for improveing skin condition according to claim 1, it is characterised in that: the skin cream matrix packet Include following component by mass percentage: moisturizer is 12%~20%, emulsifier is 1%~5% and grease be 12%~ 20%.

3. a kind of skin care item for improveing skin condition according to claim 2, it is characterised in that: the moisturizer includes sweet Oil, propylene glycol, glycine betaine and hyaluronic acid；The emulsifier includes alkyl glycosides, glycerin monostearate, hydrolecithin； The grease includes vaseline, olive oil, mineral oil, vitamin E oil.

4. a kind of skin care item for improveing skin condition according to claim 1, it is characterised in that: the kudzu root extract packet Include following component by mass percentage: daidzein 2%-5%, daidzin 5%-10%, Puerarin 10%-20% It is 8%-10% with Puerarin -7- xyloside.

5. a kind of skin care item for improveing skin condition according to claim 1, which is characterized in that the oligopeptides -1 includes such as Lower extraction step:

1) it extracts；

2) it separates；

3) in vitro culture；

4) oligopeptides -1 is separated using chromatography；

5) high performance liquid chromatography is identified.

6. a kind of skin care item for improveing skin condition according to claim 1, which is characterized in that the preparation of skin care item is taken Following steps:

I 85 degree of mixings, are then adjusted after) proportionally mixing the skin cream matrix, the kudzu root extract and deionized water PH value is to 6~8；

II it) is added after oligopeptides -1 mixes and obtains finished product.