CN109662939A - A kind of newborn composition of chest enlarge U.S., chest enlarge breast cream and preparation method thereof - Google Patents
A kind of newborn composition of chest enlarge U.S., chest enlarge breast cream and preparation method thereof Download PDFInfo
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- CN109662939A CN109662939A CN201910164888.5A CN201910164888A CN109662939A CN 109662939 A CN109662939 A CN 109662939A CN 201910164888 A CN201910164888 A CN 201910164888A CN 109662939 A CN109662939 A CN 109662939A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Abstract
The embodiment of the invention discloses a kind of newborn compositions of chest enlarge U.S., chest enlarge breast cream and preparation method thereof, belong to cosmetic technical field.The newborn composition of chest enlarge U.S. includes the component of following parts by weight: Thailand white high 25-50 parts of (PUERARIA MIRIFICA) root extract, 18-30 parts of oat (AVRNA SATIVA) beta glucan, 10-20 parts of Tujue rose (ROSA DAMASCENA) caul-fat, 5-15 parts of sturgeon roe sauce extract.The above substance carries out compounding through specific proportion and generates synergistic effect, adjusting endocrine function in vivo can be played, dredging the channel, activate mammary glandular cell, develop mammary fat cell itself again, achieve the purpose that treat the proliferation of mammary gland, chest enlarge U.S. cream, has the advantages that significant effect, safety is without any side effects and does not rebound.
Description
Technical field
The present embodiments relate to cosmetic technical fields, and in particular to a kind of chest enlarge U.S. newborn composition, chest enlarge breast cream
And preparation method thereof.
Background technique
Breast is the secondary sex characters of women, is known as " life of woman " in foreign countries, no matter pre-marital or all weighed very much after marriage
Depending on, breast is flat less than normal or the sagging beautiful curve that can not only destroy women of relaxation, the physical and mental health of women can be also seriously affected, cream
Room is flat less than normal or the relax nutritious material want of sagging main cause or nutriment proportional imbalance, wearing brassiere do not conform to
Reason, does not get enough athletic exercise, endocrine disorder etc., leads to skin of breast relaxation, and fat mass is reduced, and connective tissue tension is unbalance, and mammary gland stops
Only development or atrophy.
The women of breast augmentation was required suddenly to increase in recent years, although it is rich to there is now the methods of operation, drug, electronics physics breast strengthening apparatus
Cream, but since the factors such as its safety, reliability allow many women to hang back.
With the quickening pace of modern life, the disease incidence of the proliferation of mammary gland is in rising trend in recent years.The proliferation of mammary gland refers to mammary gland
Epithelium and proliferation of fibrous tissue, the retrogression pathological changes and progressive connective tissue of breast tissue conduit and newborn leaflet in structure
Growth, using breast pain and lump as main clinical manifestation, and as cyclically-varying is presented in menstrual cycle or mood swing,
Its main feature is that the course of disease is long, make slow progress, it is easy to recur, and canceration easily occurs for the severe proliferation of mammary gland, the atypical proliferation of mammary gland, suffers from
The probability of breast cancer is higher by 2 times of normal healthy women.The pathogenic factor of the proliferation of mammary gland includes that endocrine hormone lacks of proper care, is spiritual tight
, the excited and bad life habits often staying up late, have not enough sleep etc..The disease disease incidence was in and rose year by year in recent years
Trend, the age also increasingly becomes younger.There is the different degrees of proliferation of mammary gland there are about the women of 70-80% according to investigations, it is common
25-45 years old women.The disease has equally seriously affected women physical and mental health.
The proliferation of mammary gland is based on hormone for oral administration and operative treatment at present, but operation can only cut off local patholoic change, not release
Forming factors, other positions can still occur or continued growth；Though hormone replacement therapy can alleviate clinical symptoms in the short time, not
It can fundamentally adjust endocrine function, take for a long time and be easy to aggravate endocrine disturbance instead, and generate serious side effects and simultaneously
Disease is sent out, so not being able to satisfy clinical needs.
Therefore, healthy and beautiful chest has great significance to the body and physical and mental health of women.
Summary of the invention
For this purpose, the embodiment of the present invention provides a kind of newborn composition of chest enlarge U.S., chest enlarge breast cream and preparation method thereof, the combination
Object can play adjusting endocrine function in vivo, and dredging the channel activates mammary glandular cell, sends out mammary fat cell itself again
It educates, achievees the purpose that treat the proliferation of mammary gland, chest enlarge U.S. cream, with significant effect, safety is without any side effects and does not rebound excellent
Point.
To achieve the goals above, the embodiment of the present invention provides the following technical solutions:
In the first aspect of embodiments of the present invention, a kind of newborn composition of chest enlarge U.S., including following weight are provided
The component of number: Thailand white high 25-50 parts of (PUERARIA MIRIFICA) root extract, oat (AVRNA SATIVA) β-
18-30 parts of glucan, 10-20 parts of Tujue rose (ROSA DAMASCENA) caul-fat, 5-15 parts of sturgeon roe sauce extract.
Further, the component including following parts by weight: white high (PUERARIA MIRIFICA) root extract of Thailand
30-40 parts, 22-25 parts of oat (AVRNA SATIVA) beta glucan, Tujue rose (ROSA DAMASCENA) caul-fat 15-20
Part, 5-10 parts of sturgeon roe sauce extract.
In the second aspect of embodiments of the present invention, provides the above-mentioned newborn composition of chest enlarge U.S. and produced in chest enlarge U.S. cream
Application in product, the chest enlarge U.S. milk product includes lotion and cream.
In the third aspect of embodiments of the present invention, a kind of chest enlarge breast cream is provided, the chest enlarge breast cream is pressed
Weight percent meter includes the above-mentioned newborn composition 6-24% of chest enlarge U.S., glycine betaine 1-8%, Sodium Hyaluronate 1-6%, biology sugar
- 1 1-6% of glue, moisturizer 2-10%, thickener 2-8%, surplus are deionized water.
Further, the chest enlarge breast cream include by weight percentage the newborn composition 12-18% of above-mentioned chest enlarge U.S.,
Glycine betaine 2-5%, Sodium Hyaluronate 2-4%, -1 2-4% of biological carbohydrate gum, moisturizer 2-6%, thickener 4-8%, surplus are to go
Ionized water.
Further, the moisturizer is selected from one of glycerol, 1,3-BDO, propylene glycol, sorbierite or a variety of.
Further, the thickener is selected from carbomer sodium, rilanit special, Sodium Polyacrylate, hydroxy-ethyl acrylate/the third
One of alkene acyl dimethyltaurine sodium copolymer is a variety of.
Further, the chest enlarge breast cream further includes the preservative that weight percentage is 0.2-0.5%.
Further, the preservative is selected from grapefruit seed extract, Flos Lonicerae extractive solution, Folium Artemisiae Argyi extract, shaddock fruit and mentions
Take one of object or a variety of.
The preservative that the present invention selects is the natural plant extracts with antiseptic and inhibiting bacteria function effect, more safely and effectively.
In the fourth aspect of embodiments of the present invention, a kind of preparation method of above-mentioned chest enlarge breast cream is provided,
It the described method comprises the following steps:
1) each component is weighed by weight percentage；
2) deionized water, glycine betaine, Sodium Hyaluronate, biological carbohydrate gum -1 and moisturizer are added into water phase pot, sufficiently stirs
It mixes and heats, water phase kettle temperature keeps the temperature 10-15 minutes after rising to 85-90 DEG C；
3) Thailand white high (PUERARIA MIRIFICA) root extract, oat (AVRNA are added into oily phase pot
SATIVA) beta glucan, Tujue rose (ROSA DAMASCENA) caul-fat, sturgeon roe sauce extract and thickener, are sufficiently stirred
And heat, oily phase kettle temperature keeps the temperature 10-15 minutes after rising to 80-85 DEG C；
4) material in oily phase pot is added in water phase pot, homogeneous stirring is until form uniform lotion；
5) cooling water is added under stirring condition, after lotion is cooled to 35-40 DEG C, stops stirring, discharging；
6) filling, packaging.
White high (PUERARIA MIRIFICA) root extract of Thailand: different containing white high in the white high extract of Thailand
Flavones, it is the phytoestrogen of natural safety, has the function of moisturizing the skin, restores skin elasticity, can also promote to play
Support and the breast of plastotype effect around basal cell growth allow chest to promote the development again of adipose tissue and ligament
Portion is more compact flexible；The women low for estrogen secretion, white high isoflavones enter in vivo after can with estrogen by
Body combines, and plays weak estrogen action, and can promote its new old generation with inducing endocrine, effective stimulus mammary glandular cell and tissue
Thank to speed quickening；In addition, it is white height an isoflavones enter human body, effectively can also improve and distribute whole body everywhere fat stream
It is dynamic, promote fat to vacillate to around breast, carries out the filling and accumulation of chest enlarge.
Oat (AVRNA SATIVA) beta glucan: having a very outstanding anti-aging properties, tightening that can be instant and
Soften fine wrinkles, improves dermatoglyph degree.Unique 1,3 with Isosorbide-5-Nitrae straight-chain molecular structure, Transdermal absorption performance is good, can make
For the release carrier of active ingredient.With long-term efficient moisture-retention performance, skin can be assigned and moisten smooth sense of touch such as silk.Also
The immune function of skin can be significantly improved, enhancing improves the ability that skin resists environmental stimuli to skin sparing, promotes wound
Scar color is desalinated in healing.
Tujue rose (ROSA DAMASCENA) caul-fat: being commonly called as Rosa Damascana, can adjust female incretion, nourishes uterus,
Alleviate dysmenorrhea, improves frigidity and climacteric is uncomfortable.Especially there is good beautifying skin-protection function, outer desalination spot is supported within energy
Point promotes melanin to decompose, and improves dry skin, restores skin elasticity, and women is allowed to possess healthy flesh pale, full of elasticity
Skin is the volatile oil of optimum female health.
Sturgeon roe sauce extract: protein, nucleic acid, water soluble vitamin V are rich inC、VB1、VB2、VB3, minerals etc., it is thin
Born of the same parents' structure is similar with human skin structure, is easily absorbed by the skin, and can accelerate the synthesis of collagen, increases skin elasticity, prevents
Skin aging.Sturgeon roe sauce extract can be obtained commercially, can also extract to obtain using existing method.
Glycine betaine: being typically considered the intermediate product of life entity metabolism, and methyl group provider participates in synthetic methionine,
Be otherwise known as trimethylglycine simultaneously, is a kind of natural edible amino acid, and effect is better than ammonia popular on the market
Base acid.Glycine betaine or the natural moisture absorption factor, strong hygroscopicity can provide large quantity of moisture for skin, enable skin moment light
It is sliding wet.Glycine betaine is the vitamin with bioactivity form, the formation for protein, and DNA is repaired, the active right and wrong of enzyme
It is often important, there is brilliant osmotic pressure adjustment effect, stability, water-soluble and moisture retention is high, neutralizes pH value, antianaphylaxis.
Sodium Hyaluronate: 1, moisture-keeping function, moisture-keeping function is Sodium Hyaluronate most important effect in cosmetics, with it
He compares moisturizer, and influence of the relative humidity of ambient enviroment to its moisture retention is smaller；2, trophism, Sodium Hyaluronate are skins
The intrinsic biological substance of skin, exogenous Sodium Hyaluronate are to the endogenic supplement of skin.Lesser Sodium Hyaluronate can seep
Enter skin epidermis, promote the supply of skin-nourishing and the excretion of waste, to prevent skin aging, plays beauty and beauty treatment is made
With.
Biological carbohydrate gum -1 is a kind of linear biological polysaccharide (> 106Dalton), have and is protected immediately with long-acting moisturizing
Wet effect brings skin sense soft, that silk is sliding, pleasant for skin.Be a kind of novel moisturizer in cosmetic industry, anti-wrinkle agent,
Skin repair agent and skin sense regulator.
The embodiment of the present invention has the advantages that
The present invention is with Thailand white high (PUERARIA MIRIFICA) root extract, oat (AVRNA SATIVA) β-Portugal
Glycan, Tujue rose (ROSA DAMASCENA) caul-fat, sturgeon roe sauce extract are functional component, wherein Tujue rose (ROSA
DAMASCENA) caul-fat can adjust female incretion, make channel-stimulating, and qi and blood is logical to be adjusted, and accelerate to improve internal microcirculation；Thailand
White height (PUERARIA MIRIFICA) root extract is capable of providing safe plant female hormone substance, discharges pituitary
Hormone acts on ovary, and feedback activates mammary glandular cell, promotes mammary development；Oat (AVRNA SATIVA) beta glucan energy
Enough tightenings and softening fine wrinkles, improve skin consolidation, while also significantly improving the immune function of skin, skin is protected in enhancing
Shield；Sturgeon roe sauce extract can accelerate the synthesis of collagen, increase skin elasticity, and the above substance is carried out through specific proportion
Compounding generates synergistic effect, can play adjusting endocrine function in vivo, and dredging the channel activates mammary glandular cell, makes dug fat
Fat cell itself is developed again, achievees the purpose that treat the proliferation of mammary gland, the U.S. cream of chest enlarge, has significant effect, safety without any secondary work
With and the advantages of do not rebound.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book is understood other advantages and efficacy of the present invention easily, it is clear that described embodiment is the present invention one
Section Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not doing
Every other embodiment obtained under the premise of creative work out, shall fall within the protection scope of the present invention.
This part carries out general description to the material and test method that arrive used in present invention test.Although being
It realizes many materials used in the object of the invention and operating method is it is known in the art that still the present invention still uses up herein
It may detailed description.It will be apparent to those skilled in the art that within a context, if not specified, material therefor of the present invention and behaviour
It is well known in the art as method.
White high (PUERARIA MIRIFICA) root extract of Thailand is purchased from Guangxi Kai Tai Biotechnology Co., Ltd；Swallow
Wheat (AVRNA SATIVA) beta glucan is purchased from Guangzhou Yu Tai Chemical Industry Science Co., Ltd；Tujue rose (ROSA DAMASCENA)
Caul-fat is purchased from Foshan Sheng Yi Biotechnology Co., Ltd；Sturgeon roe sauce extract is purchased from Xi'an You Shuo Biotechnology Co., Ltd.
Embodiment 1
The chest enlarge breast cream of the present embodiment includes: by weight percentage
Thailand white high (PUERARIA MIRIFICA) root extract 11%, oat (AVRNA SATIVA) beta glucan
7%, Tujue rose (ROSA DAMASCENA) caul-fat 3%, sturgeon roe sauce extract 3%, glycine betaine 4.2%, Sodium Hyaluronate
4.5%, biological carbohydrate gum -1 2%, glycerol 4%, 1,3 butylene glycol 4%, carbomer sodium 6.2%, deionized water 51.1%.
Preparation method includes the following steps:
1) each component is weighed by weight percentage；
2) deionized water, glycine betaine, Sodium Hyaluronate, biological carbohydrate gum -1 and moisturizer are added into water phase pot, sufficiently stirs
It mixes and heats, water phase kettle temperature keeps the temperature 12 minutes after rising to 85 DEG C；
3) Thailand white high (PUERARIA MIRIFICA) root extract, oat (AVRNA are added into oily phase pot
SATIVA) beta glucan, Tujue rose (ROSA DAMASCENA) caul-fat, sturgeon roe sauce extract and thickener, are sufficiently stirred
And heat, oily phase kettle temperature keeps the temperature 10 minutes after rising to 80 DEG C；
4) material in oily phase pot is added in water phase pot, homogeneous stirring is until form uniform lotion；
5) cooling water is added under stirring condition, after lotion is cooled to 35 DEG C, stops stirring, discharging；
6) filling, packaging.
Embodiment 2
The chest enlarge breast cream of the present embodiment includes: by weight percentage
Thailand white high (PUERARIA MIRIFICA) root extract 4.7%, oat (AVRNA SATIVA) beta glucan
4.7%, Tujue rose (ROSA DAMASCENA) caul-fat 2.8%, sturgeon roe sauce extract 1%, glycine betaine 7.2%, hyalomitome
Sour sodium 5.7%, biological carbohydrate gum -1 3.2%, propylene glycol 4%, carbomer sodium 1%, rilanit special 1%, deionized water
64.7%.
The preparation method is the same as that of Example 1 for the chest enlarge breast cream of the present embodiment.
Embodiment 3
The chest enlarge breast cream of the present embodiment includes: by weight percentage
White high (PUERARIA MIRIFICA) root extract 10.5% of Thailand, the oat β-Portugal (AVRNA SATIVA) are poly-
Sugared 6.3%, Tujue rose (ROSA DAMASCENA) caul-fat 4.2%, sturgeon roe sauce extract 1%, glycine betaine 3%, hyalomitome
Sour sodium 4%, biological carbohydrate gum -1 5%, glycerol 4%, sorbierite 6%, Sodium Polyacrylate 2.8%, deionized water 53.2%.
The preparation method is the same as that of Example 1 for the chest enlarge breast cream of the present embodiment.
Embodiment 4
The chest enlarge breast cream of the present embodiment includes: by weight percentage
Thailand white high (PUERARIA MIRIFICA) root extract 6.5%, oat (AVRNA SATIVA) beta glucan
5%, Tujue rose (ROSA DAMASCENA) caul-fat 2.5%, sturgeon roe sauce extract 2.5%, glycine betaine 8%, hyaluronic acid
Sodium 5%, biological carbohydrate gum -1 4.7%, 1,3 butylene glycol 2%, carbomer sodium 4%, rilanit special 3.8%, deionized water
56%.
The preparation method is the same as that of Example 1 for the chest enlarge breast cream of the present embodiment.
Embodiment 5
The chest enlarge breast cream of the present embodiment includes: by weight percentage
Thailand white high (PUERARIA MIRIFICA) root extract 10%, oat (AVRNA SATIVA) beta glucan
4.5%, Tujue rose (ROSA DAMASCENA) caul-fat 3.4%, sturgeon roe sauce extract 2.2%, glycine betaine 5.7%, transparent
Matter acid sodium 2.6%, biological carbohydrate gum -1 5.8%, 1,3 butylene glycol 3%, propylene glycol 3%, rilanit special 2%, acrylic acid hydroxyl second
Ester/sodium acryloyldimethyl taurate copolymers 2.5%, deionized water 55.3%.
The preparation method is the same as that of Example 1 for the chest enlarge breast cream of the present embodiment.
Comparative example 1
The chest enlarge breast cream of this comparative example and the difference of embodiment 1 be only that, Tujue rose (ROSA in embodiment 1
DAMASCENA) caul-fat is substituted for white high (PUERARIA MIRIFICA) root extract of Thailand of equivalent, i.e. this comparative example
The effect of chest enlarge breast cream, ingredient included: Thailand's white high (PUERARIA MIRIFICA) root extract 14%, oat (AVRNA
SATIVA) beta glucan 7%, sturgeon roe sauce extract 3%.
Comparative example 2
The chest enlarge breast cream of this comparative example and the difference of embodiment 1 are only that: white high of the Thailand in embodiment 1
(PUERARIA MIRIFICA) root extract is substituted for Tujue rose (ROSA DAMASCENA) caul-fat of equivalent, i.e. this comparison
Example chest enlarge breast cream the effect of ingredient include: oat (AVRNA SATIVA) beta glucan 7%, Tujue rose (ROSA
DAMASCENA) caul-fat 14%, sturgeon roe sauce extract 3%.
Test case
1, the sense organ and physical and chemical index of the chest enlarge breast cream of the embodiment of the present invention are tested
Appearance: wiping of materialsing is in visual observations under temperature and non-direct sunlight indoors on skin.
Fragrance: materialsing, and is identified with smell.
PH: by the measurement of method specified in GB/T 13531.1 (dilution method).
It is heat-resisting: the culture dish for filling sample to be placed in 40 DEG C of constant incubator, taken out afterwards for 24 hours, restore to room temperature to see
Whether examine has layering or obvious Traits change.
It is cold-resistant: the culture dish for filling sample being placed in -8 DEG C of refrigerator, is taken out afterwards for 24 hours, restores to room temperature to see whether
There are layering or obvious Traits change.
The organoleptic indicator of chest enlarge breast cream made from the embodiment of the present invention and physical and chemical index test result are shown in Table 1.
1 organoleptic indicator of table and physical and chemical index test result
The sense organ and physical and chemical index of the chest enlarge breast cream of the embodiment of the present invention meet China moisturizing cream professional standard GB/
The requirement of T 1857-2013, product characteristics are stablized.
2, the sanitary index of the chest enlarge breast cream of the embodiment of the present invention is examined
The sanitary index inspection result of the chest enlarge breast cream of the embodiment of the present invention is shown in Table 2.
2 sanitary index inspection result of table
| Inspection project | Inspection result |
| Total plate count/(CFU/g) | It is not detected |
| Yeast and mold sum/(CFU/g) | It is not detected |
| Class coliform/(a/g) | It is not detected |
| Staphylococcus aureus/(a/g) | It is not detected |
| Pseudomonas aeruginosa/(a/g) | It is not detected |
| Lead/(mg/kg) | It is not detected |
| Mercury/(mg/kg) | It is not detected |
| Arsenic/(mg/kg) | It is not detected |
The chest enlarge breast cream of the embodiment of the present invention meets the regulation of " cosmetics health specification ".
3, the safety and skin irritation of the chest enlarge breast cream of the embodiment of the present invention are tested
New Zealand's kind rabbit 10 [SCXK (capital) 2005-0003, weight 1.5-2Kg] is chosen, tests first 24 hours to every
The back backbone two sides of rabbit carry out depilation processing, the left and right each 3cm × 3cm of unhairing range.Using skin auto control side
The chest enlarge breast cream about 3g of the embodiment of the present invention 1 is smeared in formula, the left spinal area of every rabbit, smears daily 1 time, continuous 14 days, right
Upper spinal area is with no treatment as control.Situations such as daily observation applies skin and compares the erythema and oedema at position, as a result sees
Table 3.
3 two groups of erythema of table and oedema result compare
The chest enlarge breast cream safety of the embodiment of the present invention is without skin irritation.
4, chest enlarge breast cream the effect of property of the embodiment of the present invention is evaluated
1 general information
245 all out-patients are risen with chest pain before and after flat less than normal, the sagging and menstruation that relaxes of breast, and mammary gland is not
Logical, the proliferation of mammary gland is chief complaint, and is divided into treatment 1-5 group and control 1-2 group, the age of two groups of patients, marriage and childbirth by random digits table
The general information comparing differences such as situation, breast type are not statistically significant (P > 0.05), are comparable, the money of two groups of cases
Material, which compares, is shown in Table 4, table 5.
4 two groups of ages of table, marriage and childbirth situation and treatment fore udder type compare
Compare before 5 two groups of treatments of table with symptom
2 treatment methods
1-5 group is treated respectively using chest enlarge breast cream made from embodiment 1-5, application method: cleaning chest and hot compress 3-5
Minute, squeeze out the amount of 1 yuan of coin-size, gently warm up heat and be uniformly applied to two sides chest skin, it then follows from bottom to top, by outer and
Interior gimmick is looped to be massaged into and be fully absorbed, and every thoracotomy massage time was preferred with 5-10 minutes, daily to use once, and 3 months
It is as a treatment course.
1-2 group is compareed respectively using chest enlarge breast cream made from comparative example 1-2, and application method is same as above.
3 curative effect determinate standards
Breast augmentation the standard of curative effect evaluation: bust increases or breast above mentions 5cm the above are special efficacys；The above are effective by 3cm；1cm
The above person is effective；1cm or less person is invalid.
Proliferation of mammary gland the standard of curative effect evaluation: lump disappears, and cream pain disappears, and does not recur after being discontinued 3 months for special efficacy；Lump contracting
Small by 1/2 or more, it is effective that cream pain, which disappears,；Mass reduction 1/3, it is effective that cream pain, which mitigates,；Lump is unchanged or increases, and pain is without slow
Solution is invalid.
4 results
By the treatment of 1 course for the treatment of, two groups of patient treatment outcomes are relatively shown in Table 6.
Table 6
Cardinal symptom and sign change comparison sheet 7 after the two treatment.
Table 7
The result shows that: the chest enlarge breast cream of 1-5 of the embodiment of the present invention changes in chest enlarge and the treatment proliferation of mammary gland and with symptom
The effect of kind aspect is substantially better than the product of comparative example 1-2.Special efficacy, effective and effective patient in treatment 1-5 group are grown
Up to the follow-up of one-year age, not yet there are chest rebound feelings after stopping using the chest enlarge breast cream of the embodiment of the present invention in patient
Condition, and do not find that adverse reaction occurs in patient.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (10)
1. a kind of newborn composition of chest enlarge U.S., which is characterized in that the component including following parts by weight: white high of Thailand
25-50 parts of (PUERARIA MIRIFICA) root extract, 18-30 parts of oat (AVRNA SATIVA) beta glucan, Tujue rose
10-20 parts of (ROSA DAMASCENA) caul-fat, 5-15 parts of sturgeon roe sauce extract.
2. the newborn composition of chest enlarge U.S. according to claim 1, which is characterized in that the component including following parts by weight: safe
White high 30-40 parts of (PUERARIA MIRIFICA) root extract of state, 22-25 parts of oat (AVRNA SATIVA) beta glucan,
15-20 parts of Tujue rose (ROSA DAMASCENA) caul-fat, 5-10 parts of sturgeon roe sauce extract.
3. a kind of application of newborn composition of chest enlarge U.S. of any of claims 1 or 2 in chest enlarge U.S. milk product, which is characterized in that
The chest enlarge U.S. milk product includes lotion and cream.
4. a kind of chest enlarge breast cream, which is characterized in that the chest enlarge breast cream includes claims 1 or 2 by weight percentage
The U.S. newborn composition 6-24% of the chest enlarge, glycine betaine 1-8%, Sodium Hyaluronate 1-6%, -1 1-6% of biological carbohydrate gum, moisturizing
Agent 2-10%, thickener 2-8%, surplus are deionized water.
5. chest enlarge breast cream according to claim 4, which is characterized in that the chest enlarge breast cream wraps by weight percentage
Include the newborn composition 12-18% of chest enlarge U.S. of any of claims 1 or 2, glycine betaine 2-5%, Sodium Hyaluronate 2-4%, biology sugar
- 1 2-4% of glue, moisturizer 2-6%, thickener 4-8%, surplus are deionized water.
6. chest enlarge breast cream according to claim 4, which is characterized in that the moisturizer be selected from glycerol, 1,3-BDO,
One of propylene glycol, sorbierite are a variety of.
7. chest enlarge breast cream according to claim 4, which is characterized in that the thickener is selected from carbomer sodium, hydrogenation castor
One of sesame oil, Sodium Polyacrylate, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers are a variety of.
8. chest enlarge breast cream according to claim 4, which is characterized in that the chest enlarge breast cream further includes that weight percent contains
Amount is the preservative of 0.2-0.5%.
9. chest enlarge breast cream according to claim 8, which is characterized in that the preservative be selected from grapefruit seed extract,
One of Flos Lonicerae extractive solution, Folium Artemisiae Argyi extract, Fructus Citri grandis extract are a variety of.
10. a kind of preparation method of chest enlarge breast cream as claimed in claim 4, which is characterized in that the method includes following steps
It is rapid:
1) each component is weighed by weight percentage；
2) deionized water, glycine betaine, Sodium Hyaluronate, biological carbohydrate gum -1 and moisturizer are added into water phase pot, is sufficiently stirred simultaneously
Heating, water phase kettle temperature keep the temperature 10-15 minutes after rising to 85-90 DEG C；
3) Thailand white high (PUERARIA MIRIFICA) root extract, oat (AVRNA SATIVA) are added into oily phase pot
Beta glucan, Tujue rose (ROSA DAMASCENA) caul-fat, sturgeon roe sauce extract and thickener, are sufficiently stirred and heat,
Oily phase kettle temperature keeps the temperature 10-15 minutes after rising to 80-85 DEG C；
4) material in oily phase pot is added in water phase pot, homogeneous stirring is until form uniform lotion；
5) cooling water is added under stirring condition, after lotion is cooled to 35-40 DEG C, stops stirring, discharging；
6) filling, packaging.
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| CN201910164888.5A CN109662939A (en) | 2019-03-05 | 2019-03-05 | A kind of newborn composition of chest enlarge U.S., chest enlarge breast cream and preparation method thereof |
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| CN201910164888.5A CN109662939A (en) | 2019-03-05 | 2019-03-05 | A kind of newborn composition of chest enlarge U.S., chest enlarge breast cream and preparation method thereof |
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| CN114767818A (en) * | 2022-05-18 | 2022-07-22 | 百臻堂国际贸易有限公司 | External composition with breast enlargement and female breast lobular hyperplasia improvement functions |
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Application publication date: 20190423 |