CN106420459A - Ginseng water live essence, preparation method thereof and facial mask containing same - Google Patents
Ginseng water live essence, preparation method thereof and facial mask containing same Download PDFInfo
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- CN106420459A CN106420459A CN201610886189.8A CN201610886189A CN106420459A CN 106420459 A CN106420459 A CN 106420459A CN 201610886189 A CN201610886189 A CN 201610886189A CN 106420459 A CN106420459 A CN 106420459A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0203—Solvent extraction of solids with a supercritical fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
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Abstract
The invention provides a ginseng water live essence and a preparation method thereof and also relates to a facial mask containing the ginseng water live essence and application of the ginseng water live essence to the production of an anti-wrinkle preparation. The ginseng water live essence comprises a ginseng root extract serving as a skin conditioning agent, a ginseng tissue culture, panaxoside, a sunflower extract, a hydrolyzed soybean fine powder and rosa centifolia flower extract, a moisturizing agent, a thickening agent and water. The ginseng water live essence can effectively prevent and eliminate wrinkles, meanwhile is suitable for neutral skin, dry skin and oily skin and extremely low in allergic possibility and surprisingly can effectively increase collagens, thereby being obvious in skin care effect, huge in market potential and wide in application prospect.
Description
Technical field
The invention belongs to cosmetic field, be related to a kind of facial treatment essence liquid, more particularly, to a kind of Radix Ginseng water live essence and
Its preparation method, additionally relates to a kind of facial film of essence of living containing this Radix Ginseng water, and this Radix Ginseng water essence alive is being given birth to
Produce the application in smoothing wrinkle preparation.
Background technology
Constantly progressive abundant with material life with social economy, cosmetics, especially skin-care cosmetics become
One of modern indispensable articles for daily use.It is known that the species of commercially available skin-care cosmetics and function are various, example
As, have moisturizing, whitening, moisturizing, oil-control, defying age, Glycerin, pore refining, blackhead of dispelling, speckle dispelling, disappear fat the effects such as.Its
In, the effect of facial treatment essence liquid (essence) is especially pronounced, and especially the female that likes to be beautiful even more firmly got by the facial film containing facial treatment essence liquid
The favor of scholar；Generally, facial treatment essence liquid contains trace element, collagen protein, serum, natural plant extract etc., therefore, its
There is the functions such as anti-aging, crease-resistant, moisturizing, whitening, despeckle.
However, commercially available facial treatment essence liquid tends not to be simultaneously adapted to neutral skin, dry skin and oily skin
Different crowd uses, and wherein portioned product also has the inapparent defect of wrinkle improvement effect, or even presence causes user mistake
The deleterious effects such as quick.
Research shows, because Radix Ginseng contains ginsenoside, panaxatriol, several mineral materials and vitamin, its comprehensive effect
There is anti-cholesterol, the blood circulation of promotion subcutaneous capillary, increase the nutrition supply of skin, prevent arteriosclerosis etc. from making
With so the effect of delay skin aging can be played；And, contained trace mineral can also adjust moisture of skin in Radix Ginseng
Balance, prevent xerosis cutiss be dehydrated, increase skin elasticity, so can give play to holding skin bright and clean tender, prevent or reduce
The effect of wrinkle of skin.
Therefore, currently a large amount of cosmetics research staff are being devoted to effectively utilizes ginseng product or its extract, to
Combine with other suitable ingredients and make brand-new essence so that this essence is simultaneously adapted to neutral skin, dryness
Skin and oily skin, wrinkle improvement effect is obvious, and it is extremely low that allergy probability is down to.
In prior art, Chinese patent CN102988199A discloses a kind of skin-tendering and anti-allergic essence, and it is by 1,3- dihydroxy
The raw materials such as base butane, propylene glycol, pyrrolidone sodium carboxylate, glycyrrhizic acid diformazan, Sargassum polysaccharides, watermiscible vitamin E are heated, newborn
Change the operations such as stirring, cooling to be prepared from；However, this skin-tendering and anti-allergic essence primarily serves the effect of moist moisturizing skin, and
Can not effective smoothing wrinkle, moreover, antiallergic effect that it possesses is added anti-allergic agent and is realized by extra, and this is certain
Production cost is increased in degree, and if also prove to remove this anti-allergic agent from another angle, remaining ingredient is to a certain degree
Upper presence leads to the risk of user allergy.
And for example, Chinese patent CN104758225A provides a kind of essence and preparation method thereof, and this essence mainly wraps
Contain：Margarita powder, Margarita extract, Glycyrrhiza glabra L. aqueous solution, hydrolysis conchiolin, Semen Pisi sativi extract, glycerol, acryloyldimethyl
Taurine ammonium/VP copolymer, xanthan gum and hyaluronate sodium etc..However, effect of this essence is mainly whitening Glycerin,
Do not have the performance of efficient smoothing wrinkle yet.
At present, the essence product of effectively utilizes Radix Ginseng or its extract is not uncommon for.For example, Chinese patent application
CN104758207A, wherein just employs Radix Ginseng extract, and achieves and significantly improve black eye, improves microcirculation, moisturizing
The outstanding effect of performance of keeping humidity；However, the technical scheme that this application is provided is due to the selection of compatibility material, both do not possessed notable
Wrinkle improvement effect, cannot guarantee that allergy probability is down to extremely low.For example, Chinese patent application CN104083641A discloses one
Plant the herbal essence of transdermal treatments, however, wherein comprising the kinds of traditional Chinese medicines such as Radix Ginseng, Rhizoma Gastrodiae, Scorpio, Flos Carthami, Rhizoma Chuanxiong, important
To medicinal therapeutic effect, substantially belong to a kind of medicine preparation, rather than the brand-new facial treatment essence liquid of desired acquisition.
Content of the invention
In order to overcome shortcomings and deficiencies present in above-mentioned prior art, the present invention is intended to provide a kind of shield of brand-new formula
So that this essence is simultaneously adapted to neutral skin, dry skin and oily skin, wrinkle improvement effect substantially, and makes skin essence
Allergy probability be down to extremely low.For this reason, in addition inventor's matching reason divides using ginseng tissue culture, Radix Ginseng root extract and
From the panaxoside monomer mixture obtaining, and selected other skin conditioning agents carry out compatibility, simultaneously using suitable moisturizing
Agent and thickening agent, to being prepared the Radix Ginseng water work essence of effect is significant by specific proportioning.
Therefore, a first aspect of the present invention, there is provided a kind of Radix Ginseng water is lived essence, its comprise by mass percentage with
Lower component：
Preferably, described Radix Ginseng water essence alive comprises following components by mass percentage：
What deserves to be explained is, the title of above-mentioned each component is international cosmetic raw material name (INCI) Chinese translation, is
Avoid ambiguity, now list each group and divide corresponding English name as follows：Water AQUA, Radix Ginseng root extract PANAX
GINSENG ROOT EXTRACT, ginseng tissue culture PANAX GINSENG TISSUE CULTURE, fourth two
Alcohol BUTYLENE GLYCOL, glycerol GLYCERIN, hyaluronate sodium SODIUM HYALURONATE, Radix Ginseng
Saponin GINSENOSIDES, Flos Helianthi extract HELIANTHUS ANNUUS (SUNFLOWER) FLOWER
EXTRACT, hydrolyzed soy fine powder HYDROLYZED SOY FLOUR, Rosa centifolia L flower extract ROSA
CENTIFOLIA FLOWER EXTRACT, 1,2- pentanediol PENTYLENE GLYCOL, xanthan gum XANTHAN
GUM.And, wherein, Radix Ginseng root extract, ginseng tissue culture, ginsenoside, Flos Helianthi extract, hydrolyzed soy are thin
, all as skin conditioning agent, butanediol, glycerol, hyaluronate sodium and 1,2- pentanediol are all as guarantor for powder and Rosa centifolia L flower extract
Humectant, xanthan gum is as thickening agent, and water is as solvent.
In the essence it is further preferred that described Radix Ginseng water is lived, the water as solvent is the pure water of electrical conductivity≤2 μ S/cm,
And this pure electrical conductivity of water records at room temperature.
It is further preferred that living in essence in described Radix Ginseng water, described Radix Ginseng root extract, the culture of described ginseng tissue
Thing and described ginsenoside are derived from any one or more Radix Ginseng following independently of one another：Radix Ginseng, suncured white ginseng root, Radix Ginseng Rubra, Radix Ginseng,
Wild ginseng, Park Ginseng, Transplant Wild Ginseng, Korean Ginseng, Radix Panacis Quinquefolii.
It is further preferred that living in essence in described Radix Ginseng water, described Radix Ginseng root extract, described Flos Helianthi extract
At least one in thing and described Rosa centifolia L flower extract is by supercritical CO2Fluids extraction obtains.It is known that CO2Safety,
Nontoxic, cheap and easy to get, and supercritical CO2The diffusion coefficient with similar gas and the dissolving power being provided simultaneously with liquid, surface is opened
Power is zero it is thus possible to penetrate into rapidly among Radix Ginseng root, Flos Helianthi and Rosa centifolia L flower, its elite of high efficiency extraction, and no
The residual of hazardous solvent；Therefore, whole extraction process efficiency high, extract obtained (extract) very high purity, pure natural, nothing are appointed
What chemical contamination.
It is further preferred that living in essence in described Radix Ginseng water, described butanediol is BDO.Due to butanediol
There are isomerss, therefore, alternately, described butanediol can also be 1,2- butanediol, 2,3-butanediol, 1,3- fourth two
Alcohol, or BDO and 1,2- butanediol, 2,3-butanediol, the mixture of 1,3 butylene glycol.
It is further preferred that living in essence in described Radix Ginseng water, described ginsenoside includes：Rg1、Re、Rf、Rb1、
Rc、Rb2、Rb3、Rd、Rh2.Wherein, ginsenoside Rg1 can rapid recovery fatigue, slow down aging, also have stimulating central nervous system,
The effect of suppression platelet aggregation, vasodilator and blood pressure lowering；Ginsenoside Re can raise plasma corticosterone concentration, have simultaneously
Effect expansion of blood vessels；Ginsenoside Rf can make the intestinal contraction that acetylcholine causes weaken, and has decreased heart rate and Bipolar blood
Pressure acts on, and also has certain hemolytic activity；Ginsenoside Rb1 can increase synthesis and the release of acetylcholine, improves memory
Power；PanaxosideRb2 has reduction intracellular Ca2+, antioxidation, removes interior free yl and improves myocardial ischemia reperfusion injury
Deng effect；Ginsenoside Rc is close with ginsenoside Rb1, Rb2 pharmacological action, and ginsenoside Rc, Rb1, Rb2 are used in mixed way
Also have and necessarily stabilize effect；Ginsenoside Rb3 can strengthen myocardial function, blood circulation promoting, protection human autoimmune system
System；Ginsenoside Rd belongs to a kind of scarce ginsenoside, and its pharmacologically active is higher, be not only able to blood circulation promoting additionally it is possible to
Remove free radical, possess radioprotective effect to a certain extent；Ginsenoside Rh 2 can be effective against fatigue.Additionally, being worth saying
Bright, listed above it is the panaxoside monomer preferably using, it is of course possible to according to ginseng raw material's in actual production
The difference of different or extract part and select other panaxoside monomers.
Above-mentioned Radix Ginseng water work essence, can use on direct convenience ground, can act also as one of raw materials of cosmetics such as facial film；On
State Radix Ginseng water essence alive and be simultaneously adapted to neutral skin, dry skin and oily skin, also show that it has by experiment aobvious
, any allergic phenomena in a large amount of triers in the effect smoothing away wrinkles writing, and is confirmed by detection chemical examination, this Radix Ginseng
The probability that water essence alive becomes anaphylactogen is extremely low.And, above-mentioned Radix Ginseng water lives essence using easily, in cleaning skin
Afterwards, take and be coated on face in right amount, gently pat and can absorb.
Additionally, during trier uses, inventor is found surprisingly that, above-mentioned Radix Ginseng water essence alive also additionally has
Promote the effect of increased collagen, this makes skin more whitening, the smooth and high resilience of trier, some women is tried out
The skin of person is more ruddy tender and lovely.
A kind of a second aspect of the present invention, there is provided the preparation side of the essence alive of Radix Ginseng water described in first aspect present invention
Method, comprises the following steps：
(1) accurately weigh each component by mass percentage；Wherein, all vessel used are weighed, equipment all answers prior warp
Cross strict cleaning and sterilizing；After weighing each material, the emulsifying pot after cleaning and sterilizing can be directly added into it is also possible to first temporarily be contained in
In different vessel；
(2) add the water accurately weighing, hyaluronate sodium, butanediol, glycerol and xanthan gum in emulsifying pot, be sufficiently stirred for
And heat, make emulsifying kettle temperature rise to 85-90 DEG C, then insulated and stirred more than 30 minutes, in order to be incubated froth breaking；
(3) open cooling circulating water, continue stirring, make emulsifying kettle temperature drop to 40-48 DEG C, preferably drop to 45
DEG C, it is subsequently adding the Radix Ginseng root extract accurately weighing, ginseng tissue culture, ginsenoside, Flos Helianthi extract, hydrolysis
Soybean fine powder, Rosa centifolia L flower extract and 1,2- pentanediol, stir；
(4) stirring be cooled to emulsifying kettle temperature be less than 38 DEG C after, preferably stirring be cooled to emulsifying kettle temperature be equal to 37
After DEG C, stop stirring, discharging.Additionally, in this step (4), it should take sample censorship after stirring cooling, to detect that product is
No qualified, just can discharging after detection is qualified.And, the product of gained is described Radix Ginseng water work elite after this step (4) discharging
Liquid, will be centrally located interior in standing, need further quality testing；Detect further qualified after, as needed, can be by it
Raw material as other cosmetics transports to other factories, or, as end product, subsequent implementation fill, packaging, spray
Code, if sampling observation is qualified, finished product is put in storage.
A third aspect of the present invention, additionally provides a kind of facial film, and it contains the essence alive of Radix Ginseng water described in first aspect present invention
Magnificent liquid.The facial film being provided is not limited to its objective for implementation or functional effect, as long as it contains described in first aspect present invention
Radix Ginseng water work essence, just becomes the facial film described in third aspect present invention.
Finally, a fourth aspect of the present invention, additionally provides Radix Ginseng water described in first aspect present invention and lives essence in production
Application in smoothing wrinkle preparation.
In sum, Radix Ginseng water provided by the present invention essence alive is not only able to effectively prevent, smoothes away wrinkles, and fits simultaneously
Together in neutral skin, dry skin and oily skin and allergy probability is extremely low, and, can effectively increase unexpectedly glue
Former albumen, thus having significant skin effect, its market potential is huge, has a extensive future.Additionally, it is provided by the present invention
Radix Ginseng water live essence preparation method simple to operate it is easy to industrialization large-scale production；Facial film provided by the present invention is same
There is the property of described Radix Ginseng water essence alive and corresponding effect, Radix Ginseng water provided by the present invention essence alive removes in production
Application in wrinkle preparation, also can play the effect of whitening despeckle, moisturizing smoothing wrinkle to the skin of user.
Brief description
Fig. 1 uses the skin microgram before and after Radix Ginseng water of the present invention essence alive for trier, shows crows-feet
Removal situation with wing of nose stricture of vagina；Wherein, D0 is shown that using front skin microgram, and D28 is shown that persistently using 28 days
Skin microgram afterwards；
Fig. 2 is collagen protein fluorescent labeling figure inside and outside Skin Cell, wherein：A is matched group, is shown that not using this
The Skin Cell of bright described Radix Ginseng water work essence；B is experimental group, is shown that persistently employing Radix Ginseng water of the present invention lives
Skin Cell after 1 month for the essence；C is also experimental group, is shown that persistently to employ Radix Ginseng water work elite of the present invention
Skin Cell after 3 months for the liquid；
Fig. 3 is the gross mass block diagram (ng/10 of contained collagen protein in every 1,000,000 Skin Cells counting6Cells),
Wherein, A is matched group, shows total containing collagen protein in the Skin Cell of essence of not lived using Radix Ginseng water of the present invention
Quality；B is experimental group, shows persistently to employ Radix Ginseng water of the present invention and live and contains in Skin Cell after 1 month for the essence
The gross mass of collagen protein；C is also experimental group, shows that persistently employing Radix Ginseng water of the present invention lived essence after 3 months
Skin Cell in containing collagen protein gross mass；
Fig. 4 is the preparation method flow chart of Radix Ginseng water of the present invention essence alive, and wherein, A phase is：Water, hyaluronic acid
Sodium, butanediol, glycerol and xanthan gum, B phase is：Radix Ginseng root extract, ginseng tissue culture, ginsenoside, Flos Helianthi carry
Take thing, hydrolyzed soy fine powder, Rosa centifolia L flower extract and 1,2- pentanediol.
Specific embodiment
With reference to specific embodiment, the present invention is further elaborated, but the present invention is not limited to following embodiment party
Formula.
First aspect, there is provided a kind of Radix Ginseng water work essence, it comprises following components by mass percentage：
In a preferred embodiment, described Radix Ginseng water essence alive comprises following components by mass percentage：
In a further preferred embodiment, described water is the pure water of electrical conductivity≤2 μ S/cm.
In a further preferred embodiment, described Radix Ginseng root extract, described ginseng tissue culture with described
Ginsenoside is derived from any one or more Radix Ginseng following independently of one another：Radix Ginseng, suncured white ginseng root, Radix Ginseng Rubra, Radix Ginseng, wild ginseng,
Park Ginseng, Transplant Wild Ginseng, Korean Ginseng, Radix Panacis Quinquefolii.
In a further preferred embodiment, described Radix Ginseng root extract, described Flos Helianthi extract and described
At least one in Rosa centifolia L flower extract is by supercritical CO2Fluids extraction obtains.
In a further preferred embodiment, described butanediol is BDO.
In a further preferred embodiment, described ginsenoside includes：Rg1、Re、Rf、Rb1、Rc、Rb2、Rb3、
Rd、Rh2.
A kind of second aspect, there is provided the preparation method of the essence alive of the Radix Ginseng water described in first aspect, walks including following
Suddenly：
(1) accurately weigh each component by mass percentage；
(2) add the water accurately weighing, hyaluronate sodium, butanediol, glycerol and xanthan gum in emulsifying pot, be sufficiently stirred for
And heat, make emulsifying kettle temperature rise to 85-90 DEG C, then insulated and stirred more than 30 minutes；
(3) open cooling circulating water, continue stirring, make emulsifying kettle temperature drop to 40-48 DEG C, be subsequently adding accurate title
The Radix Ginseng root extract that takes, ginseng tissue culture, ginsenoside, Flos Helianthi extract, hydrolyzed soy fine powder, Rosa centifolia L flower
Extract and 1,2- pentanediol, stir；
(4) stirring be cooled to emulsifying kettle temperature be less than 38 DEG C after, stop stirring, discharging.
The third aspect, additionally provides a kind of facial film, and it contains the Radix Ginseng water work essence described in first aspect.
Fourth aspect, additionally provides Radix Ginseng water described in first aspect and lives application in producing smoothing wrinkle preparation for the essence.
Embodiment 1
Radix Ginseng water work essence, the mass percent of wherein each component are prepared using preparation method flow process as shown in Figure 4
For：
Wherein, pure water conductivity ＜ 1 μ S/cm；Radix Ginseng root extract, Flos Helianthi extract and Rosa centifolia L flower extract are equal
By supercritical CO2Fluids extraction obtains；Radix Ginseng root extract is derived from Radix Ginseng Rubra, wild ginseng and Korean Ginseng；Ginseng tissue culture
From Radix Ginseng, suncured white ginseng root, Radix Ginseng Rubra, Radix Ginseng and wild ginseng；Ginsenoside is derived from Radix Ginseng Rubra, Radix Ginseng, wild ginseng, Park Ginseng, shifting
SHANSHEN, Korean Ginseng and Radix Panacis Quinquefolii, and include：Rg1、Re、Rf、Rb1、Rc、Rb2、Rb3、Rd、Rh2.
Concrete steps include：
(1) accurately weigh each component by mass percentage；Wherein, all vessel used, equipment all warps in advance are weighed
Cross strict cleaning and sterilizing；After weighing each material, first temporarily it is contained in different vessel；
(2) add the pure water accurately weighing, hyaluronate sodium, BDO, glycerol and xanthan gum in emulsifying pot, fill
Divide and stir and heat, make emulsifying kettle temperature rise to 85-90 DEG C, then insulated and stirred 50 minutes；
(3) open cooling circulating water, continue stirring, make emulsifying kettle temperature drop to 45 DEG C, be subsequently adding and accurately weigh
Radix Ginseng root extract, ginseng tissue culture, ginsenoside, Flos Helianthi extract, hydrolyzed soy fine powder, Rosa centifolia L flower carry
Take thing and 1,2- pentanediol, stir；
(4) stirring is cooled to after emulsifying kettle temperature is less than 38 DEG C, stops stirring, takes sample censorship, to detect that product is
No qualified, after detection is qualified, discharging.
Embodiment 2
Radix Ginseng water work essence, the mass percent of wherein each component are prepared using preparation method flow process as shown in Figure 4
For：
Wherein, pure water conductivity=2 μ S/cm；Flos Helianthi extract and Rosa centifolia L flower extract are by supercritical CO2Stream
Body extraction obtains；Radix Ginseng root extract is derived from Radix Ginseng, suncured white ginseng root, Park Ginseng, Transplant Wild Ginseng；Ginseng tissue culture is derived from sun-dried
Ginseng and wild ginseng；Ginsenoside is derived from Radix Ginseng Rubra, wild ginseng, Park Ginseng, Radix Ginseng, Korean Ginseng and Radix Panacis Quinquefolii, and includes：Rg1、Re、
Rf、Rb1、Rc、Rb2、Rb3、Rd、Rh2.
Concrete steps include：
(1) accurately weigh each component by mass percentage；Wherein, all vessel used, equipment all warps in advance are weighed
Cross strict cleaning and sterilizing；After weighing each material, first temporarily it is contained in different vessel；
(2) add the pure water accurately weighing, hyaluronate sodium, 1,3 butylene glycol, glycerol and xanthan gum in emulsifying pot, fill
Divide and stir and heat, make emulsifying kettle temperature rise to 85-90 DEG C, then insulated and stirred 40 minutes；
(3) open cooling circulating water, continue stirring, make emulsifying kettle temperature drop to 40 DEG C, be subsequently adding and accurately weigh
Radix Ginseng root extract, ginseng tissue culture, ginsenoside, Flos Helianthi extract, hydrolyzed soy fine powder, Rosa centifolia L flower carry
Take thing and 1,2- pentanediol, stir；
(4) stirring is cooled to after emulsifying kettle temperature is less than 37 DEG C, stops stirring, takes sample censorship, to detect that product is
No qualified, after detection is qualified, discharging.
Embodiment 3
Radix Ginseng water work essence, the mass percent of wherein each component are prepared using preparation method flow process as shown in Figure 4
For：
Wherein, pure water conductivity ＜ 0.9 μ S/cm；Radix Ginseng root extract is by supercritical CO2Fluids extraction obtains；Radix Ginseng
Root extract is derived from Korean Ginseng；Ginseng tissue culture is derived from Radix Ginseng, suncured white ginseng root, Radix Ginseng Rubra and wild ginseng；Ginsenoside is derived from
Radix Ginseng Rubra, Radix Ginseng, wild ginseng, Park Ginseng and Radix Panacis Quinquefolii, and include：Rg1、Re、Rf、Rb1、Rc、Rb2、Rb3、Rd、Rh2.
Concrete steps include：
(1) accurately weigh each component by mass percentage；Wherein, all vessel used, equipment all warps in advance are weighed
Cross strict cleaning and sterilizing；After weighing each material respectively, according to the following steps, it is directly added in the emulsifying pot after cleaning and sterilizing；
(2) pure water accurately weighing, hyaluronate sodium, 1,4- butanediol, 2,3- butanediol, 1,3- are added in emulsifying pot
Butanediol, glycerol and xanthan gum, are sufficiently stirred for and heat, and make emulsifying kettle temperature rise to 85-90 DEG C, then insulated and stirred 35
Minute；
(3) open cooling circulating water, continue stirring, make emulsifying kettle temperature drop to 45 DEG C, be subsequently adding and accurately weigh
Radix Ginseng root extract, ginseng tissue culture, ginsenoside, Flos Helianthi extract, hydrolyzed soy fine powder, Rosa centifolia L flower carry
Take thing and 1,2- pentanediol, stir；
(4) stirring is cooled to after emulsifying kettle temperature is less than 36 DEG C, stops stirring, takes sample censorship, to detect that product is
No qualified, after detection is qualified, discharging.
Additionally, inventor is carried out to the Radix Ginseng water work essence obtained by embodiment 1～3 according further to about specification and standard
Multiple batches of complete examination, wherein, inspection project is with method as shown in table 1 below：
The photosensitive index of table 1, hygienic chemistry index and microbiological indicator inspection project and method
Wherein, assay is as shown in table 2 below～4：
(1) photosensitive index
Character：This product material body is brownish red transparency liquid, abnormal smells from the patient delicate fragrance.
The photosensitive index test result of table 2
(2) hygienic chemistry index
Table 3 hygienic chemistry index test result
| Sequence number | Inspection project | Index | Testing result |
| 1 | Hydrargyrum | ≤1mg/Kg | Qualified |
| 2 | Lead (in terms of lead) | ≤40mg/Kg | Qualified |
| 3 | Arsenic (in terms of arsenic) | ≤10mg/Kg | Qualified |
| 4 | pH | 4.0-8.5 | 6.05 |
(3) microbiological indicator
Table 4 microbiological indicator assay
| Sequence number | Inspection project | Index | Testing result |
| 1 | Total plate count | ≤1000CFU/g | ＜ 10CFU/g |
| 2 | Yeast and mold sum | ≤100CFU/g | ＜ 10CFU/g |
| 3 | Colibacillus of excrement | Must not detect | Do not detect |
| 4 | Staphylococcus aureuses | Must not detect | Do not detect |
| 5 | Pseudomonas aeruginosa | Must not detect | Do not detect |
Additionally, one has crows-feet and uses the Radix Ginseng water obtained by embodiment 1 with the random women trier of wing of nose stricture of vagina
Essence alive, the daily morning and evening, after washing one's face, takes and is coated on face in right amount, gently pat；Fig. 1 is the skin microgram of her face,
Wherein, D0 is shown that using front skin microgram, and D28 is shown that persistently using the skin microgram after 28 days；From Fig. 1
In can clearly indicate out, persistently live after essence 28 days using this Radix Ginseng water, crows-feet is all significantly reduced with wing of nose stricture of vagina, phase
The skin answering position is than using front more smooth.
Further, inventor is unexpectedly conducive to the shadow that collagen protein increases to Radix Ginseng water of the present invention work essence
Sound has carried out related experiment：60 close for the skin of 50-65 one full year of life triers are divided into 3 groups, wherein, A is matched group,
Do not use this Radix Ginseng water work essence, detected after 1 month；B is experimental group, persistently using this Radix Ginseng water work essence 1
Month, detected 1 month date of expiry of the period；C is also experimental group, and use time is longer, that is, persistently using this Radix Ginseng water work elite
Liquid 3 months, was detected 3 months dates of expiry of the period.Invention is entered to the collagen protein inside and outside Skin Cell using fluorescent marker method
Go labelling, its testing result is as shown in Figure 2；Therefrom it can clearly be observed that collagen inside and outside Skin Cell in experimental group C
Albumen at most, illustrates over a period to come, and more for a long time using this Radix Ginseng water work essence, collagen protein is more.
Then, inventor also have detected above control group A, in every 1,000,000 Skin Cells in experimental group B, experimental group C
The gross mass of contained collagen protein, and it is depicted as block diagram.As shown in Figure 3 it is seen that every 1,000,000 Skin Cells in experimental group B
In every 1,000,000 Skin Cells in the total mass ratio control group A of interior contained collagen protein, the gross mass of contained collagen protein is high about
20%, and every 1,000,000 in the total mass ratio control group A of contained collagen protein in every 1,000,000 Skin Cells in experimental group C
In Skin Cell, the gross mass of contained collagen protein is high by about 66%；Thus, equally confirm conclusions, that is, in the regular period
Interior, the time using this Radix Ginseng water essence alive is longer, and Skin Cell just can be made to obtain more collagen protein.This exceeds to anticipate
The experimental result of material is probably that Radix Ginseng water of the present invention is lived the synergistic result of multiple skin conditioning agent in essence.
Above the specific embodiment of the present invention is described in detail, but it has been intended only as example, the present invention has not limited
It is formed on particular embodiments described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and
Substitute also all among scope of the invention.Therefore, the impartial conversion made without departing from the spirit and scope of the invention and
Modification, all should cover within the scope of the invention.
Claims (10)
1. a kind of Radix Ginseng water live essence it is characterised in that described Radix Ginseng water is lived essence comprise by mass percentage following
Component：
2. Radix Ginseng water according to claim 1 is lived, and it is characterised in that described Radix Ginseng water is lived, essence presses quality hundred to essence
Divide and comprise following components than meter：
3. Radix Ginseng water according to claim 1 and 2 lives essence it is characterised in that described water is electrical conductivity≤2 μ S/cm
Pure water.
4. Radix Ginseng water according to claim 1 and 2 lives essence it is characterised in that described Radix Ginseng root extract, described people
Ginseng tissue culture and described ginsenoside are derived from any one or more Radix Ginseng following independently of one another：Radix Ginseng, suncured white ginseng root, red
Ginseng, Radix Ginseng, wild ginseng, Park Ginseng, Transplant Wild Ginseng, Korean Ginseng, Radix Panacis Quinquefolii.
5. Radix Ginseng water according to claim 1 and 2 live essence it is characterised in that described Radix Ginseng root extract, described to
At least one in day sunflower extract and described Rosa centifolia L flower extract is by supercritical CO2Fluids extraction obtains.
6. Radix Ginseng water according to claim 1 and 2 lives essence it is characterised in that described butanediol is BDO.
7. Radix Ginseng water according to claim 1 and 2 lives essence it is characterised in that described ginsenoside includes：Rg1、
Re、Rf、Rb1、Rc、Rb2、Rb3、Rd、Rh2.
8. a kind of Radix Ginseng water according to any one of claim 1～7 live essence preparation method it is characterised in that
Comprise the following steps：
(1) accurately weigh each component by mass percentage；
(2) add the water accurately weighing, hyaluronate sodium, butanediol, glycerol and xanthan gum in emulsifying pot, be sufficiently stirred for and add
Heat, makes emulsifying kettle temperature rise to 85-90 DEG C, then insulated and stirred more than 30 minutes；
(3) open cooling circulating water, continue stirring, make the emulsifying kettle temperature drop to 40-48 DEG C, be subsequently adding and accurately weigh
Radix Ginseng root extract, ginseng tissue culture, ginsenoside, Flos Helianthi extract, hydrolyzed soy fine powder, Rosa centifolia L flower extract
Thing and 1,2- pentanediol, stir；
(4) stirring be cooled to emulsifying kettle temperature be less than 38 DEG C after, stop stirring, discharging.
9. a kind of facial film is it is characterised in that the Radix Ginseng water that described facial film contains any one of with good grounds claim 1～7 is lived
Essence.
10. application in producing smoothing wrinkle preparation for the essence alive of the Radix Ginseng water according to any one of claim 1～7.
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| CN109998948A (en) * | 2017-12-29 | 2019-07-12 | 辽宁上药好护士健康科技有限公司 | A kind of preparation method of red ginseng sleep mask |
| CN111388398A (en) * | 2020-04-13 | 2020-07-10 | 佛山秘码中医馆有限公司 | Chinese herbal medicine liquid for increasing skin barrier function |
| CN112334205A (en) * | 2018-06-21 | 2021-02-05 | Gs 加德士 | Solvent composition for extracting natural substance |
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| CN112334205B (en) * | 2018-06-21 | 2022-09-06 | Gs 加德士 | Solvent composition for extracting natural substance |
| CN111388398A (en) * | 2020-04-13 | 2020-07-10 | 佛山秘码中医馆有限公司 | Chinese herbal medicine liquid for increasing skin barrier function |
| CN112675091A (en) * | 2021-01-07 | 2021-04-20 | 阙仁传 | Skin stop-motion liquid and preparation method thereof |
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| CN106420459B (en) | 2019-09-20 |
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