CN109662311A - Ferment and its preparation method and application with function of relaxing bowel - Google Patents
Ferment and its preparation method and application with function of relaxing bowel Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/10—Laxatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The invention discloses a kind of ferment and its preparation method and application with function of relaxing bowel, the ferment extracts fermentation by the raw material and complex microorganism of following parts by weight and is made: 25-68 parts of draft Chinese medicine, 32-76 parts and ingredient 5.8-7.9 parts of fruit, the additive amount of complex microorganism is 0.08-0.15 times of raw material gross weight, draft Chinese medicine is sea-buckthorn, cordate houttuynia, rhizoma polygonati, one of radish seed and pueraria lobata are a variety of, fruit is apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, one of pineapple and blackcurrant are a variety of, ingredient is Hy drolyzed Skin Powder, the mixture of pumpkin and oligofructose, complex microorganism is acetic acid bacteria, one of lactic acid bacteria and saccharomycete are a variety of.Ferment provided by the present invention can improve intestinal flora, and bowel relaxing functions improve mouthfeel；Its raw material is easy to get, and required equipment is simple, and technique is controllable, and actual promotional value is important.
Description
Technical field
The invention belongs to functional food science and technology fields, and in particular to a kind of ferment with function of relaxing bowel
And its preparation method and application.
Background technique
With the quickening of modern life rhythm and the change of dietary structure, dietary fiber etc. promotes the food of intestines peristalsis
The factors such as intake is reduced, and high protein diet intake is excessive, and physical training is reduced in addition, and life stress is excessive so that constipation by
Gradually become one of the common disease for enabling modern perplex, disease incidence is in the trend being stepped up, and has seriously affected the life of people
Bioplasm amount and life security.
The constipation of omnibus survey studies have shown that shows apparent ascendant trend with the increase at age, and China is old
The developing state of total amount expansion, increment speed-raising is presented in population size, with the arrival in aging of population epoch, China's constipation crowd
More expand.The problem of actively resolving constipation, can not only make the elderly from the hardship of constipation, increase the life matter of the elderly
Amount, moreover it is possible to the generation of constipation related disease is reduced, it is significant.
The teiology and Pathological Physiology of constipation be still it is unknown, it is a kind of complicated symptom that clinic is common, mainly
Refer to that defecation frequency is reduced, feces volume is reduced, excrement is dry and hard, defecation is hard, defecation is not clean feel, there is no satisfied happy sense after defecation
Etc..Constipation patient is usually also with symptoms such as insomnia, dreaminess, agitation, depression and anxiety.
Currently, different according to the cause of disease of constipation, therapeutic scheme has general life treatment, drug therapy, biofeedback instruction
Experienced and operative treatment.General life treatment be by adjusting life style, adjusting mentality is gradually recovered defecation with suitable movement
Smoothly state, can fundamentally mitigation capability constipation；Therapeutic scheme is divided into external preparation and oral preparations, enema
It is exactly a kind of common external application purgatives, short-term relief symptom can be played the role of, symptom, which still has, after deactivating even aggravates, and controls
Mark does not effect a permanent cure, and oral preparations are generally by the permeability for changing enteron aisle or use some irritating plant cathartics, such as big
Huang, folium sennae etc. achieve the purpose that defecation, but the problems such as having the side effect for capturing catharsis, easily causing smooth amyotrophia more, add
Constipation again.Biofeedback training or operative treatment spininess are to serious organic constipation patient, such as serious obstinate Colonic transit
Dysfunction type constipation patient.
The narrow definition of ferment is enzyme, and it is indispensable with cell activity that enzyme is that human body sustains life, it is also cell weight
The constituent wanted.The internal movable number of ferment decides the health status of people, " ferment how many, life is with regard to how many ".
In fact, ferment as a kind of functional food oneself through in Japan and China Taiwan fashionable decades, it is with fresh
Vegetable and fruit etc. be raw material, the fermentation through microorganism produce a large amount of enzyme, amino acid, microelement, bacterium two second generations
It thanks to the multiple nutritional components such as object, the digestion and absorption function of human body, resistance building etc. can be enhanced.
Up to the present, there is not yet in relation to draft Chinese medicine, fruit, Hy drolyzed Skin Powder, pumpkin and oligofructose
Deng the extracted fermentation of joint after application in relax bowel and defecation, alleviation or treatment constipation report.
Summary of the invention
The purpose of the present invention is overcome the deficiencies of the prior art and provide a kind of ferment with function of relaxing bowel.
It is a further object of the present invention to provide the preparation methods of the ferment object.
It is yet another object of the invention to provide the applications of the ferment.
A kind of ferment with function of relaxing bowel provided by the invention, by the raw material and complex microorganism of following parts by weight
Fermentation is extracted to be made: 25-68 parts of draft Chinese medicine, 32-76 parts and ingredient 5.8-7.9 parts of fruit, the addition of the complex microorganism
Amount is 0.08-0.15 times of the raw material gross weight.
Specifically, the draft Chinese medicine is one of sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata or a variety of.
Specifically, the fruit is apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, pineapple and black
One of gallon is a variety of.
Specifically, the ingredient is the mixture of Hy drolyzed Skin Powder, pumpkin and oligofructose.
Specifically, the complex microorganism is one of acetic acid bacteria, lactic acid bacteria and saccharomycete or a variety of.
Further, in the ferment provided by the present invention with function of relaxing bowel, the complex microorganism is vinegar
The mixture of sour bacterium, lactic acid bacteria and saccharomycete, the acetic acid bacteria is acetic acid bacteria Acetobacter sp BNCC336433, described
Lactic acid bacteria is one of lactobacillus acidophilus, the dry bacterium of bifid, Lactobacillus casei, lactobacillus plantarum, and the saccharomycete is preservation volume
Number health Probiomplex SA-12 type Saccharomyces cerevisiae is praised for 2018351 saccharomycete one hundred of CCTCC NO:M
One hundred good health Probiomplex SA-12 type, the additive amount of the complex microorganism are the 0.09-0.13 of the raw material gross weight
Times.
Preferably, the vinegar in the ferment provided by the present invention with function of relaxing bowel, in the complex microorganism
The mass ratio of sour bacterium, lactic acid bacteria and saccharomycete is (0.86-1.05): (0.95-1.18): (1.15-1.28).
Still further, hydrolyzing glue in the ingredient in the ferment provided by the present invention with function of relaxing bowel
The mass ratio of former albumen powder, pumpkin and oligofructose is (1.18-1.42): (0.75-1.06): (7.27-9.05).
Further, the ferment provided by the present invention with function of relaxing bowel, by following parts by weight raw material with
Complex microorganism extracts fermentation and is made: 35-59 parts of draft Chinese medicine, 43-65 parts and ingredient 6.2-7.8 parts of fruit.
Specifically, the draft Chinese medicine is the mixture of sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata.
Specifically, the fruit is apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, pineapple and black
The mixture of gallon.
Further, the ferment provided by the present invention with function of relaxing bowel, by following parts by weight raw material with
Complex microorganism extracts fermentation and is made: 46-54 parts of draft Chinese medicine, 48-56 parts and ingredient 6.6-7.5 parts of fruit, described compound micro-
The additive amount of biology is 0.098-0.124 times of the raw material gross weight.
Specifically, in the draft Chinese medicine, sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata mass ratio be (0.58-
0.76):(1.15-1.38):(2.19-3.05):(1.57-1.86): (1.27-2.05)。
Specifically, in the fruit, apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, pineapple with it is black
The mass ratio of gallon is (3.38-4.62): (0.85-1.24): (1.27-2.15): (1.75-1.98): (2.27-3.25):
(0.75-1.36):(1.29-2.05): (2.25-2.86):(1.27-2.05)。
Specifically, in the ingredient, the mass ratio of Hy drolyzed Skin Powder, pumpkin and oligofructose is (1.25-
1.40):(0.82-1.02):(7.35-8.85)。
Specifically, the complex microorganism is the mixture of acetic acid bacteria, lactic acid bacteria and saccharomycete, and the acetic acid bacteria, cream
The mass ratio of sour bacterium and saccharomycete is (0.88-1.05): (0.95-1.15): (1.18-1.25).
In the above-mentioned technical solutions, in the ferment provided by the present invention with function of relaxing bowel, in the ingredient
In, the molecular weight of the Hy drolyzed Skin Powder is 500-15000 dalton, and protein content >=90wt%.
Preferably, in the above-mentioned technical solutions, in the ferment provided by the present invention with function of relaxing bowel, in institute
It states in ingredient, content >=90wt% of DP 2-8 in the oligofructose.
Further, in the above-mentioned technical solutions, in the ferment provided by the present invention with function of relaxing bowel, institute
Stating the viable bacteria concentration in complex microorganism is 5 × 108-6.8×1012 cfu/g。
Preferably, in the above-mentioned technical solutions, described in the ferment provided by the present invention with function of relaxing bowel
Viable bacteria concentration in complex microorganism is 7.5 × 109-8.8×1011cfu/g。
The present invention provides the preparation methods of the above-mentioned ferment with function of relaxing bowel, include the following steps:
S1, draft Chinese medicine is weighed according to the ratio, and the water of described 8-12 times of weight of draft Chinese medicine is added, impregnate 40-120min,
After boiling 60-180min, decoction liquor of leaching, filter residue adds the boiling boiling 60- of described 8-12 times of weight of draft Chinese medicine
180min, the secondary decoction liquor of leaching merge decoction liquor and obtain Chinese medicine extract；
S2, fresh clean fruit is weighed according to the ratio, carry out smashing processing respectively, homogenize process is carried out after mixing, adjust
PH value is 6.0-6.8, and fruit slurry is made；
S3, ingredient and complex microorganism are weighed in proportion, by fruit slurry, ingredient and composite microbial obtained by step S2
Object is added in Chinese medicine extract obtained by step S1 simultaneously, and mixing is fermented at 30-35 DEG C, until pol in fermentation liquid
It terminates fermentation when lower than 8.5g/L, filters, after being concentrated and sterilizing to obtain the final product.
In the above-mentioned technical solutions, described to boil to be decocted slowly using mild fire in step S1.
In the above-mentioned technical solutions, in step S3, the fermentation time is 16-160h.
In the above-mentioned technical solutions, in step S3, the multiple of the concentration is 2-4 times.
In the above-mentioned technical solutions, in step S3, the sterilizing is ultra high temperature short time sterilization.
Preferably, in the above-mentioned technical solutions, in step S3, the sterilizing is the 2-8s that sterilizes at 115-125 DEG C.
The present invention also provides the ferment that above-mentioned ferment or above-mentioned preparation method are prepared to prepare relax bowel and defecation, alleviate
Or the application in the treatment food of constipation, drug or health care product.
Ferment with function of relaxing bowel of the invention can increase or reduce according to corresponding ratio in production, such as big
Large-scale production can by kilogram or as unit of ton, small-scale production can also in grams, and weight can increase or reduce,
But the raw material weight proportioning of soup processed constant rate between each composition.
There is the present invention ferment of function of relaxing bowel to have the advantages that
(1) present invention is with apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, pineapple and blackcurrant etc.
Fruit, the draft Chinese medicine such as sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata, while add Hy drolyzed Skin Powder, pumpkin and
Oligofructose is as ingredient, through compound microorganism ferments such as acetic acid bacteria, lactic acid bacteria and saccharomycete, and combines and decocts extractive technique,
Obtained ferment improves intestinal flora, and bowel relaxing functions improve raw material nutrient utilization, improves mouthfeel；
(2) the ferment edible safety provided by the present invention with function of relaxing bowel is reliable, takes quickly, mouthfeel is suitable
In, it is easy to carry, and have distinctive fragrance, it is good to take experience effect；
(3) raw material of the ferment provided by the present invention with function of relaxing bowel is easy to get, condition needed for preparing and equipment
Simply, simple process is controllable, has highly important actual promotional value.
Specific embodiment
With reference to embodiment, the embodiment of the present invention is furthur described in detail.Following embodiment is used for
Illustrate the present invention, but be not limited to protection scope of the present invention, protection scope of the present invention is subject to claims.
Unless otherwise specified, experiment reagent used in the embodiment of the present invention and material etc. are commercially available, if not having
Body indicates, the conventional means that technological means used in the embodiment of the present invention is well known to the skilled person.
Raw materials used source in the embodiment of the present invention and comparative example:
Fruit used is commercially available fresh fruit；
Draft Chinese medicine used is commercial product；
Hy drolyzed Skin Powder, pumpkin and oligofructose (content of DP2-8 is 92.5 wt%) used are commercially available production
Product.
In complex microorganism used, the acetic acid bacteria is that (number is commercially available acetic acid bacteria Acetobacter sp
BNCC336433, viable bacteria concentration 8.2 × 109cfu/g)；The lactic acid bacteria be commercially available lactobacillus acidophilus (viable bacteria concentration 7.8 ×
1010Cfu/g), the dry bacterium of bifid (viable bacteria concentration 8.2 × 1010Cfu/g), Lactobacillus casei (viable bacteria concentration 8.8 × 1010cfu/
G), lactobacillus plantarum (viable bacteria concentration 7.5 × 1010One of cfu/g)；The saccharomycete is that deposit number is CCTCC NO:M
2018351 saccharomycete one hundred praise one hundred Jia Kang of health Probiomplex SA-12 type Saccharomyces cerevisiae
Probiomplex SA-12 type, the saccharomycete were preserved in China typical culture collection center on 06 06th, 2018
(abbreviation CCTCC；Address: Wuhan, China, Wuhan University；Postcode: 430072), viable bacteria concentration is 8.5 × 1010cfu/g。
In preparation process of the present invention, unless otherwise specified, used means are this field conventional technology.
A kind of ferment with function of relaxing bowel of embodiment 1
1, raw material proportioning:
Draft Chinese medicine includes:
13 parts of sea-buckthorn, 8 parts of cordate houttuynia, 12 parts of radish seed and 10 parts of pueraria lobata；
Fruit includes:
4 parts of apple, 8 parts of blood orange, 2 parts of Cranberry, 5 parts of white grape, 9 parts of pineapple and 5 parts of blackcurrant；
Ingredient includes:
0.879 part of Hy drolyzed Skin Powder, 0.621 part of pumpkin and 5.801 parts of oligofructose；
Complex microorganism includes:
3.5 parts and 4.8 parts of saccharomycete of acetic acid bacteria.
2, preparation method:
S1, draft Chinese medicine is weighed according to the ratio, and the water of 10 times of weight of draft Chinese medicine is added, 90min is impregnated, using text
Fiery slow pan-fried, after boiling 120min, decoction liquor of leaching, filter residue adds the water of 10 times of weight of draft Chinese medicine, using text
It is fiery slow pan-fried, 120min is boiled, the secondary decoction liquor of leaching merges decoction liquor and obtains Chinese medicine extract；
S2, fresh clean fruit is weighed according to the ratio, carry out smashing processing respectively, homogenize process is carried out after mixing, adjust
PH value is 6.0-6.8, and fruit slurry is made；
S3, ingredient and complex microorganism are weighed in proportion, by fruit slurry, ingredient and composite microbial obtained by step S2
Object is added in Chinese medicine extract obtained by step S1 simultaneously, and mixing, ferment 64-96h at 30-35 DEG C, until fermentation liquid
Middle pol be lower than 8.5g/L when terminate fermentation, filtering, concentration 3 times after, and at 118 DEG C sterilize 3s after to obtain the final product.
A kind of ferment with function of relaxing bowel of embodiment 2
1, raw material proportioning:
Draft Chinese medicine includes:
4.28 parts of sea-buckthorn, 8.37 parts of cordate houttuynia, 16.87 parts of rhizoma polygonati, 11.40 parts of radish seed and 11.07 parts of pueraria lobata；
Fruit includes:
11.48 parts of apple, blood orange 3.19 parts, 5.69 parts of blueberry, 5.43 parts of Cranberry, 8.36 parts of red grape, white grape
2.78 parts, 5.39 parts of red pomegranate, 7.24 parts of pineapple and 5.45 parts of blackcurrant；
Ingredient includes:
0.905 part of Hy drolyzed Skin Powder, 0.645 part of pumpkin and 5.651 parts of oligofructose；
Complex microorganism includes:
4.47 parts and 4.94 parts of saccharomycete of the dry bacterium of 3.75 parts of acetic acid bacteria, bifid.
2, preparation method:
S1, draft Chinese medicine is weighed according to the ratio, and the water of 10 times of weight of draft Chinese medicine is added, 90min is impregnated, using text
Fiery slow pan-fried, after boiling 150min, decoction liquor of leaching, filter residue adds the water of 10 times of weight of draft Chinese medicine, using text
It is fiery slow pan-fried, 150min is boiled, the secondary decoction liquor of leaching merges decoction liquor and obtains Chinese medicine extract；
S2, fresh clean fruit is weighed according to the ratio, carry out smashing processing respectively, homogenize process is carried out after mixing, adjust
PH value is 6.0-6.8, and fruit slurry is made；
S3, ingredient and complex microorganism are weighed in proportion, by fruit slurry, ingredient and composite microbial obtained by step S2
Object is added in Chinese medicine extract obtained by step S1 simultaneously, and mixing, ferment 64-128h at 30-35 DEG C, until fermentation liquid
Middle pol be lower than 8.5g/L when terminate fermentation, filtering, concentration 4 times after, and at 124 DEG C sterilize 2s after to obtain the final product.
A kind of ferment with function of relaxing bowel of embodiment 3
1, raw material proportioning:
Draft Chinese medicine includes:
6.08 parts of sea-buckthorn, 11.34 parts of cordate houttuynia, 14.27 parts of rhizoma polygonati, 8.48 parts of radish seed and 4.98 parts of pueraria lobata；
Fruit includes:
7.58 parts of apple, blood orange 5.37 parts, 8.42 parts of blueberry, 3.79 parts of Cranberry, 6.36 parts of red grape, white grape
7.18 parts, 6.14 parts of red pomegranate, 5.24 parts of pineapple and 8.92 parts of blackcurrant；
Ingredient includes:
1.205 parts of Hy drolyzed Skin Powder, 0.942 part of pumpkin and 5.253 parts of oligofructose；
Complex microorganism includes:
5.93 parts and 7.24 parts of saccharomycete of acetic acid bacteria.
2, preparation method:
S1, draft Chinese medicine is weighed according to the ratio, and the water of 10 times of weight of draft Chinese medicine is added, 90min is impregnated, using text
Fiery slow pan-fried, after boiling 120min, decoction liquor of leaching, filter residue adds the water of 10 times of weight of draft Chinese medicine, using text
It is fiery slow pan-fried, 120min is boiled, the secondary decoction liquor of leaching merges decoction liquor and obtains Chinese medicine extract；
S2, fresh clean fruit is weighed according to the ratio, carry out smashing processing respectively, homogenize process is carried out after mixing, adjust
PH value is 6.0-6.8, and fruit slurry is made；
S3, ingredient and complex microorganism are weighed in proportion, by fruit slurry, ingredient and composite microbial obtained by step S2
Object is added in Chinese medicine extract obtained by step S1 simultaneously, and mixing, ferment 64-96h at 30-35 DEG C, until fermentation liquid
Middle pol be lower than 8.5g/L when terminate fermentation, filtering, concentration 3 times after, and at 118 DEG C sterilize 3s after to obtain the final product.
A kind of ferment with function of relaxing bowel of embodiment 4
1, raw material proportioning:
Draft Chinese medicine includes:
15.34 parts of sea-buckthorn, 18.06 parts of cordate houttuynia, 6.45 parts of radish seed and 25.15 parts of pueraria lobata；
Fruit includes:
12.38 parts of apple, blood orange 9.34 parts, 11.16 parts of Cranberry, 9.67 parts of white grape, 8.54 parts of red pomegranate, pineapple
9.44 parts and 8.47 parts of blackcurrant；
Ingredient includes:
1.485 parts of Hy drolyzed Skin Powder, 2.257 parts of pumpkin and 3.458 parts of oligofructose；
Complex microorganism includes:
7.37 parts of saccharomycete.
2, preparation method:
S1, draft Chinese medicine is weighed according to the ratio, and the water of 10 times of weight of draft Chinese medicine is added, 90min is impregnated, using text
Fiery slow pan-fried, after boiling 150min, decoction liquor of leaching, filter residue adds the water of 10 times of weight of draft Chinese medicine, using text
It is fiery slow pan-fried, 150min is boiled, the secondary decoction liquor of leaching merges decoction liquor and obtains Chinese medicine extract；
S2, fresh clean fruit is weighed according to the ratio, carry out smashing processing respectively, homogenize process is carried out after mixing, adjust
PH value is 6.0-6.8, and fruit slurry is made；
S3, ingredient and complex microorganism are weighed in proportion, by fruit slurry, ingredient and composite microbial obtained by step S2
Object is added in Chinese medicine extract obtained by step S1 simultaneously, and mixing, ferment 64-128h at 30-35 DEG C, until fermentation liquid
Middle pol be lower than 8.5g/L when terminate fermentation, filtering, concentration 4 times after, and at 124 DEG C sterilize 2s after to obtain the final product.
A kind of ferment with function of relaxing bowel of comparative example 1
1, raw material proportioning:
Draft Chinese medicine includes:
4.28 parts of sea-buckthorn, 8.37 parts of cordate houttuynia, 15.98 parts of rhizoma polygonati, 11.52 parts of radish seed and 10.98 parts of pueraria lobata；
Fruit includes:
11.37 parts of apple, blood orange 3.24 parts, 5.69 parts of blueberry, 5.57 parts of Cranberry, 8.36 parts of red grape, white grape
2.84 parts, 5.39 parts of red pomegranate, 7.19 parts of pineapple and 5.55 parts of blackcurrant；
Ingredient includes:
0.905 part of Hy drolyzed Skin Powder, 0.645 part of pumpkin and 5.651 parts of oligofructose；
Complex microorganism includes:
6.98 parts of 6.15 parts of acetic acid bacteria and the dry bacterium of bifid.
2, preparation method:
S1, draft Chinese medicine is weighed according to the ratio, and the water of 10 times of weight of draft Chinese medicine is added, 90min is impregnated, using text
Fiery slow pan-fried, after boiling 150min, decoction liquor of leaching, filter residue adds the water of 10 times of weight of draft Chinese medicine, using text
It is fiery slow pan-fried, 150min is boiled, the secondary decoction liquor of leaching merges decoction liquor and obtains Chinese medicine extract；
S2, fresh clean fruit is weighed according to the ratio, carry out smashing processing respectively, homogenize process is carried out after mixing, adjust
PH value is 6.0-6.8, and fruit slurry is made；
S3, ingredient and complex microorganism are weighed in proportion, by fruit slurry, ingredient and composite microbial obtained by step S2
Object is added in Chinese medicine extract obtained by step S1 simultaneously, and mixing, ferment 64-128h at 30-35 DEG C, until fermentation liquid
Middle pol be lower than 8.5g/L when terminate fermentation, filtering, concentration 4 times after, and at 124 DEG C sterilize 2s after to obtain the final product.
The human experiment of experimental example ferment relax bowel and defecation is tested
1, test method:
Selection 80 suffer from the patient of constipation, observe the curative effect of ferment of the present invention.
Diagnostic criteria: 3 persons are less than within stool one week, without organic constipation person and habitual constipation person.
Subject is randomly divided into 5 groups, every group of 16 people are grouped situation are as follows:
Group 1: ferment prepared by stomach-filling embodiment 1；
Group 2: ferment prepared by stomach-filling embodiment 2；
Group 3: ferment prepared by stomach-filling embodiment 3；
Group 4: ferment prepared by stomach-filling embodiment 4；
Group 5: ferment prepared by stomach-filling comparative example 1；
Group 1-5 is taken twice daily, and each 120m1 takes 7 days after being diluted with warm water.
It is consistent before diet and amount of exercise and experiment between experiment periods, indices are tested in test-meal to be started and terminate
When respectively test it is primary.
2, observation index:
2.1 efficiency indexes: inquiring and record to subject daily, while recording before subject takes given the test agent
6 days and experiment when the case where；Record the variation of subject's test-meal front and back defecation frequency.
2.2 defecation conditions: according to difficult defecation degree (abdominal pain or anus burn feeling, bearing down, sense of discomfort, whether just frequency
But difficult defecation and measure the symptoms such as few) be divided into one to level Four, count integrated value.
Level-one (0 point): defecation is normal；
Second level (1 point): only bearing down, sense of discomfort；
Three-level (2 points): bearing down, sense of discomfort are obvious, or have just frequency but difficult defecation and measure less, less abdominal pain or anus occur
Door burn feeling；
Level Four (3 points): often there is abdominal pain or anus burn feeling, influence defecation.
2.3 excrement states: it is divided into one to three-level according to Bristol fecal character classification.
Level-one (0 point): smooth and soft as sausage or snake；As sausage, there is slight crack on surface；Soft agglomerate, some limbus
(being easily drained)；
Second level (1 point): sausage shape, but have agglomerate；Loose bulk, edge roughness, as slimy excrement；
Three-level (2 points): the hard group of separation, as fruit stone (should not be discharged).
3, test result
Each group case curative effect comparison result see the table below shown in 1.
1 each group case efficacy result comparison sheet of table
By above-mentioned 1 result of table it is found that the ferment relax bowel and defecation effect of group 1-4 is shown as significantly, effect most preferably organizes 2,
Group 1 is suitable with 3 effects of group, and better than group 4, and ferment effect prepared by organizing 5 is poor.
In conclusion the embodiment of the present invention is with apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, spinach
The fruit such as trailing plants and blackcurrant, the draft Chinese medicine such as sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata, while adding Hydrolyzed Collagen
Powder, pumpkin and oligofructose are as ingredient, through compound microorganism ferments such as acetic acid bacteria, lactic acid bacteria and saccharomycete, and combine and decoct
Extractive technique is boiled, obtained ferment improves intestinal flora, and bowel relaxing functions improve raw material nutrient utilization, improves mouthfeel；This
Ferment edible safety provided by inventive embodiments with function of relaxing bowel is reliable, takes quickly, mouthfeel is moderate, convenient for taking
Band, and have distinctive fragrance, it is good to take experience effect；With the ferment of function of relaxing bowel provided by the embodiment of the present invention
Raw material be easy to get, prepare needed for condition and equipment it is simple, simple process is controllable, have highly important actual promotional value.
Although above the present invention is described in detail with a general description of the specific embodiments,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, fall within the scope of the claimed invention without departing from theon the basis of the spirit of the present invention.
Claims (10)
1. a kind of ferment with function of relaxing bowel, which is characterized in that mentioned by the raw material and complex microorganism of following parts by weight
Fermentation is taken to be made: 25-68 parts of draft Chinese medicine, 32-76 parts and ingredient 5.8-7.9 parts of fruit, the additive amount of the complex microorganism
It is 0.08-0.15 times of the raw material gross weight；
The draft Chinese medicine is one of sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata or a variety of；
The fruit is one of apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, pineapple and blackcurrant
Or it is a variety of；
The ingredient is the mixture of Hy drolyzed Skin Powder, pumpkin and oligofructose；
The complex microorganism is one of acetic acid bacteria, lactic acid bacteria and saccharomycete or a variety of.
2. the ferment according to claim 1 with function of relaxing bowel, which is characterized in that the complex microorganism is vinegar
The mixture of sour bacterium, lactic acid bacteria and saccharomycete, the acetic acid bacteria is acetic acid bacteria Acetobacter sp BNCC336433, described
Lactic acid bacteria is one of lactobacillus acidophilus, the dry bacterium of bifid, Lactobacillus casei, lactobacillus plantarum, and the saccharomycete is preservation volume
Number health Probiomplex SA-12 type Saccharomyces cerevisiae is praised for 2018351 saccharomycete one hundred of CCTCC NO:M
One hundred good health Probiomplex SA-12 type, the additive amount of the complex microorganism are the 0.09-0.13 of the raw material gross weight
Times；Preferably, the mass ratio of the acetic acid bacteria, lactic acid bacteria and saccharomycete is (0.86-1.05): (0.95-1.18): (1.15-
1.28)。
3. the ferment according to claim 1 or 2 with function of relaxing bowel, which is characterized in that in the ingredient, hydrolysis
The mass ratio of collagen protein powder, pumpkin and oligofructose is (1.18-1.42): (0.75-1.06): (7.27-9.05).
4. the ferment according to claim 1-3 with function of relaxing bowel, which is characterized in that by following weight
Part raw material and complex microorganism extract fermentation and be made: 35-59 part of draft Chinese medicine, 43-65 parts of fruit with ingredient 6.2-7.8 parts；
The draft Chinese medicine is the mixture of sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata；
The fruit is the mixing of apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, pineapple and blackcurrant
Object.
5. the ferment according to claim 4 with function of relaxing bowel, which is characterized in that by the raw material of following parts by weight
It extracts fermentation with complex microorganism to be made: 46-54 parts of draft Chinese medicine, 48-56 parts and ingredient 6.6-7.5 parts of fruit, described compound
The additive amount of microorganism is 0.098-0.124 times of the raw material gross weight；
In the draft Chinese medicine, sea-buckthorn, cordate houttuynia, rhizoma polygonati, radish seed and pueraria lobata mass ratio be (0.58-0.76): (1.15-
1.38):(2.19-3.05):(1.57-1.86):(1.27-2.05)；
In the fruit, apple, blood orange, blueberry, Cranberry, red grape, white grape, red pomegranate, the quality of pineapple and blackcurrant
Than for (3.38-4.62): (0.85-1.24): (1.27-2.15): (1.75-1.98): (2.27-3.25): (0.75-1.36):
(1.29-2.05):(2.25-2.86):(1.27-2.05)；
In the ingredient, the mass ratio of Hy drolyzed Skin Powder, pumpkin and oligofructose is (1.25-1.40): (0.82-
1.02):(7.35-8.85)；
The complex microorganism is the mixture of acetic acid bacteria, lactic acid bacteria and saccharomycete, and the acetic acid bacteria, lactic acid bacteria and saccharomycete
Mass ratio be (0.88-1.05): (0.95-1.15): (1.18-1.25).
6. the ferment according to claim 1-5 with function of relaxing bowel, which is characterized in that in the ingredient
In,
The molecular weight of the Hy drolyzed Skin Powder is 500-15000 dalton, and protein content >=90wt%；
And/or in the oligofructose DP 2-8 content >=90wt%.
7. the ferment according to claim 1-6 with function of relaxing bowel, which is characterized in that described compound micro-
Viable bacteria concentration in biology is 5 × 108-6.8×1012Cfu/g, preferably 7.5 × 109-8.8×1011cfu/g。
8. a kind of preparation method of the ferment described in any one of claim 1-6 with function of relaxing bowel, which is characterized in that packet
Include following steps:
S1, draft Chinese medicine is weighed according to the ratio, and the water of described 8-12 times of weight of draft Chinese medicine is added, impregnate 40-120min, boil
After 60-180min, decoction liquor of leaching, filter residue adds the boiling boiling 60-180min of described 8-12 times of weight of draft Chinese medicine,
The secondary decoction liquor of leaching merges decoction liquor and obtains Chinese medicine extract；
S2, fresh clean fruit is weighed according to the ratio, carry out smashing processing respectively, homogenize process is carried out after mixing, adjust pH value
For 6.0-6.8, fruit slurry is made；
S3, ingredient and complex microorganism are weighed in proportion, fruit slurry, ingredient and complex microorganism obtained by step S2 is same
When be added in Chinese medicine extract obtained by step S1, mix, ferment at 30-35 DEG C, until fermentation liquid in pol be lower than
It terminates fermentation when 8.5g/L, filters, after being concentrated and sterilizing to obtain the final product.
9. the preparation method of the ferment according to claim 8 with function of relaxing bowel, which is characterized in that
It is described to boil to be decocted slowly using mild fire in step S1；
And/or in step S3, the fermentation time is 16-160h；
And/or in step S3, the multiple of the concentration is 2-4 times；
And/or in step S3, the sterilizing is ultra high temperature short time sterilization, and preferably sterilize at 115-125 DEG C 2-8s.
What 10. the described in any item ferment of claim 1-7 or the described in any item preparation methods of claim 8-9 were prepared
Application of the ferment in preparation relax bowel and defecation, the food of alleviation or treatment constipation, drug or health care product.
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| CN110025501A (en) * | 2019-05-13 | 2019-07-19 | 武汉森澜生物科技有限公司 | The composition and its preparation method and application to keep the skin wet for skin |
| CN110973547A (en) * | 2019-12-20 | 2020-04-10 | 湖南橘色科技有限责任公司 | Rhizoma polygonati enzyme jelly and preparation method thereof |
| CN113017082A (en) * | 2021-03-16 | 2021-06-25 | 蜡笔小新（福建）食品工业有限公司 | Magma ferment beverage convenient to human absorption and preparation facilities thereof |
| WO2024055983A1 (en) * | 2022-09-14 | 2024-03-21 | 南京纽邦生物科技有限公司 | Composition of pumpkin seed protein and use thereof |
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| CN107125745A (en) * | 2017-06-30 | 2017-09-05 | 张萌 | Adjust ferment of gut flora and bowel relaxing functions and preparation method thereof |
| CN108783431A (en) * | 2018-06-04 | 2018-11-13 | 江苏万能生物科技有限公司 | A kind of fruit ferment and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106174179A (en) * | 2016-07-11 | 2016-12-07 | 佛山市朗达信息科技有限公司 | There is the enzyme composition of effect of relaxing bowel, ferment effervescent granule and preparation method |
| CN107125745A (en) * | 2017-06-30 | 2017-09-05 | 张萌 | Adjust ferment of gut flora and bowel relaxing functions and preparation method thereof |
| CN108783431A (en) * | 2018-06-04 | 2018-11-13 | 江苏万能生物科技有限公司 | A kind of fruit ferment and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110025501A (en) * | 2019-05-13 | 2019-07-19 | 武汉森澜生物科技有限公司 | The composition and its preparation method and application to keep the skin wet for skin |
| CN110025501B (en) * | 2019-05-13 | 2022-01-18 | 武汉森澜生物科技有限公司 | Composition for supplementing moisture to skin and preparation method and application thereof |
| CN110973547A (en) * | 2019-12-20 | 2020-04-10 | 湖南橘色科技有限责任公司 | Rhizoma polygonati enzyme jelly and preparation method thereof |
| CN113017082A (en) * | 2021-03-16 | 2021-06-25 | 蜡笔小新（福建）食品工业有限公司 | Magma ferment beverage convenient to human absorption and preparation facilities thereof |
| WO2024055983A1 (en) * | 2022-09-14 | 2024-03-21 | 南京纽邦生物科技有限公司 | Composition of pumpkin seed protein and use thereof |
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Application publication date: 20190423 |