CN109646521A - A kind of menstruction regulating and pain relieving red date-walnut drink - Google Patents

A kind of menstruction regulating and pain relieving red date-walnut drink Download PDF

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Publication number
CN109646521A
CN109646521A CN201910154673.5A CN201910154673A CN109646521A CN 109646521 A CN109646521 A CN 109646521A CN 201910154673 A CN201910154673 A CN 201910154673A CN 109646521 A CN109646521 A CN 109646521A
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parts
hours
walnut
added
pain relieving
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李长明
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Weifang Shumei Biotechnology Co Ltd
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Weifang Shumei Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a kind of menstruction regulating and pain relieving red date-walnut drinks.The raw material of the menstruction regulating and pain relieving red date-walnut drink is in parts by mass, comprising: 4-6 parts of walnut, 4-6 parts of jujube, 15-20 parts of motherwort, 8-10 parts of Radix Salviae Miltiorrhizae, 8-10 parts of Radix Angelicae Sinensis, 8-10 parts of safflower, 8-10 parts of radix rehmanniae preparata, 8-10 parts of China rose, 4-6 parts of semen sojae atricolor, it is brown sugar 8-10 parts old, 4-6 parts of ferine honey.The preparation that the present invention passes through reasonable compatibility and science, the menstruction regulating and pain relieving red date-walnut drink being prepared adjusts endocrine disorder, solve menstruation postponement, blood stasis, amount less, palace cold, color be dark, dysmenorrhea, premenstrual swollen breasts, paramenia, pregnancy are difficult, pregnant preceding menstruation regulating, supports the problems such as palace, warm palace, with activating microcirculation and removing stasis medicinal, delay menopause and other effects, facilitate production and post-abortion miscellaneous disease and uterus maintenance, has a vast market foreground.

Description

A kind of menstruction regulating and pain relieving red date-walnut drink
Technical field
The present invention relates to field of food, and in particular to a kind of menstruction regulating and pain relieving red date-walnut drink.
Background technique
Today's society, with the acceleration of people's life rhythm, living environment constantly change, and subhealth group increasingly increases, The health problem of the public is also more and more prominent.Menstruation is the physiological phenomenon that women is necessarily undergone, and healthy women is average to be had throughout one's life 400 menstruations, the women more than eighty per cant will receive the puzzlement of dysmenorrhea.Dysmenorrhea has been modern female most pain in the neck feelings, almost 50 or more percent women is suffering from dysmenorrhea, with natural environment, the change of social environment, and operating pressure, emotional change, Psychological pressure, the diet disorder for resulting in many female friend's physiological periods such as irregular, causes many people's dysmenorrheas, serious person It but will cause infertile.
Dysmenorrhea is one of most common gynaecology's symptom, refers to before and after passing through or lower abdominal pain, falling inflation occurs in the menstrual period, with The soreness of waist or other uncomfortable, serious symptom influence quality of life persons.Dysmenorrhea is divided into primary dysmenorrhea and secondary two class, primary pain Referred to dysmenorrhea of the reproductive organs without organic disease, account for 90% or more dysmenorrhea, the occurrence cause of primary dysmenorrhea is complex, main It to fall off with the excessively preceding retroversioflexion in hypoplasia of uterus, uterus, endometrium bulk, menses outflow is obstructed and forefront in menstrual blood Parathyrine increase etc. is related, is furthermore also influenced by spirit, neural factors.It is " dysmenorrhea ", or " dysmenorrhea " that Chinese medicine, which is also known as this disease,. Its etiology and pathogenesis is that QI-blood circulation is unsmooth.Clinical syndrome differentiation is often divided into qi depression to blood stasis, cold-dampness stagnates, deficiency of yang endogenous cold, deficient qi and blood, liver Five card types of kidney deficiency;Acquired dysmenorrhea refers to the dysmenorrhea as caused by pelvic cavity organic disease.Cardinal symptom is with the menstrual cycle Regular attacks with underbelly pain, can be with the symptoms such as nausea,vomiting,diarrhea, dizziness, out of strength, complexion is whitened, is gone out when serious Cold sweat.Therefore, Chinese medicine is developed to prevent and treat the pain that dysmenorrhea reduces women.
Currently, in the market treat dysmenorrhea drug or more, the dosage form for having Chinese medicine, Western medicine etc. different, have it is oral, The different form of therapy such as built-in.Treating dysmenorrhea should be few as far as possible with or without narcotic-based painkillers object, generates to avoid human body anti- Pharmacological property and additive.Western medicine dysmenorrhea is palliative based on calmness to relieve pain, and side effect is bigger, but also meeting Drug dependence is generated, palliative, dietetic regulation effect is slow, and difficulty becomes effective.If a kind of menstruction regulating and pain relieving jujube walnut can be developed Dew, temporary solution are effected a permanent cure again, must can obtain the favor of vast dysmenorrhea patient.
Summary of the invention
In view of the above-mentioned deficiencies in the prior art, the present invention provides a kind of menstruction regulating and pain relieving red date-walnut drinks.
A kind of raw material of menstruction regulating and pain relieving jujube is in parts by mass, comprising: 4-6 parts of walnut, 4-6 parts of jujube, motherwort 15-20 Part, 8-10 parts of Radix Salviae Miltiorrhizae, 8-10 parts of Radix Angelicae Sinensis, 8-10 parts of safflower, 8-10 parts of radix rehmanniae preparata, 8-10 parts of China rose, 4-6 parts of semen sojae atricolor, old brown sugar 8-10 parts, 4-6 parts of ferine honey.
Preferably, the raw material of the menstruction regulating and pain relieving jujube is in parts by mass, comprising: 4-6 parts of walnut, 4-6 parts of jujube, benefit are female 15-20 parts careless, 8-10 parts of Radix Salviae Miltiorrhizae, 8-10 parts of Radix Angelicae Sinensis, 8-10 parts of safflower, 8-10 parts of radix rehmanniae preparata, 8-10 parts of China rose, 4-6 parts of semen sojae atricolor, Old brown sugar 8-10 parts, 4-6 parts of ferine honey, 0.5-1.5 parts of complex polysaccharide composition.
The complex polysaccharide composition includes one of laminarin, polysaccharide from Dunaliella salina, laver amylose or a variety of.
Preferably, the complex polysaccharide composition is by laminarin, polysaccharide from Dunaliella salina, laver amylose (1-5) in mass ratio: (1-5): (1-5) mixing.
The laminarin the preparation method comprises the following steps:
Kelp is cleaned to be placed at 55-60 DEG C and dry, pulverize by I, obtains pretreated raw material;Pretreated raw material is set Yu Shuizhong impregnates 2-6 hours, obtains soak, after water-bath is heated to the 20-40% of soak volume at 85-95 DEG C, is added The 3-6wt% solution of trichloroacetic acid of the 20-40% of soak volume stands 12-16 hours at 2-5 DEG C, centrifugation, on gained The ethyl alcohol of 1-3 times of supernatant quality is added in clear liquid, stirs evenly, is centrifuged, is precipitated after removing supernatant, water dissolution is added Afterwards, vacuum freeze drying is handled, and obtains Thick many candies;
The water of 5-15 times of Thick many candies quality is added into above-mentioned Thick many candies by II, dialyses 60-120 hours at 2-5 DEG C, often 6-12h changes a water, acquired solution through vacuum freeze drying to get.
The preparation method of the polysaccharide from Dunaliella salina and the preparation method of the laminarin are essentially identical, only replace with kelp Salt algae.
The preparation method of the laver amylose and the preparation method of the laminarin are essentially identical, only replace with kelp Seaweed.
The manufacture craft of the menstruction regulating and pain relieving red date-walnut drink, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, is mixed Material, mixture is put into reaction pot, and 5-15 times of mixture quality of water is added, is placed at 25-35 DEG C and impregnates 2-5 hours, take The raw material of immersion treatment is obtained after out;
The raw material of immersion treatment, complex polysaccharide composition are placed in reaction pot by II, and the material quality 5- of immersion treatment is added 15 times of water is placed at 95-98 DEG C and decocts 1-4 hours, and filtering obtains first time decoction liquor and material residue, then to will be in material residue The water of 5-15 times of material residue quality is added, continues to be placed in decocting 1-4 hours at 95-98 DEG C, obtains the second decoction liquor, merges for the first time Decoction liquor and the second decoction liquor are stood, filtering, and old brown sugar is then added into gained filtered fluid, and mixing is placed at 85-95 DEG C Relative density 1.21-1.25 is boiled, it is cooling, ferine honey is added after being cooled to 40-55 DEG C, mixes, cooling, canned, packaging, To obtain the final product.
Preferably, the manufacture craft of the menstruction regulating and pain relieving red date-walnut drink, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, is mixed Material is placed in progress supersonic airstream broken wall treatment at subzero 8 DEG C of subzero 10-, after being crushed to 200-600 mesh, subzero after taking-up Supersonic airstream broken wall treatment is carried out at subzero 8 DEG C of 10-, after being crushed to 200-600 mesh, is freezed 1-3 hours, then thaw 3-6 Hour, it then freezes 1-3 hours, finally defrosting 3-6 hours, obtains raw material powder;
Raw material powder, complex polysaccharide composition are placed in reaction pot by II, and the water of 5-15 times of raw material powder quality is added, sets Decocted 1-4 hours at 95-98 DEG C, filter, obtain first time decoction liquor and material residue, then to will in material residue be added material residue quality 5-15 times of water continues to be placed in decocting 1-4 hours at 95-98 DEG C, obtains the second decoction liquor, merges first time decoction liquor and second Decoction liquor is stood, filtering, and old brown sugar is then added into gained filtered fluid, and mixing is placed at 85-95 DEG C and boils to relatively close Spend 1.21-1.25, it is cooling, ferine honey is added after being cooled to 40-55 DEG C, mixes, it is cooling, it is canned, packaging to get.
It is highly preferred that the manufacture craft of the menstruction regulating and pain relieving red date-walnut drink, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, is mixed Material is placed at progress supersonic airstream broken wall treatment at subzero 8 DEG C of subzero 10-, after being crushed to 200-600 mesh, zero after taking-up Supersonic airstream broken wall treatment is carried out at subzero 8 DEG C of lower 10-, after being crushed to 200-600 mesh, is freezed 1-3 hours, then thaw 3- It 6 hours, then freezes 1-3 hours, finally defrosting 3-6 hours, obtains raw material powder;
Raw material powder, complex polysaccharide composition are placed in reaction pot by II, and 5-15 times of material quality of immersion treatment is added Water is placed at 95-98 DEG C and decocts 1-4 hours, and centrifugation obtains first time decoction liquor and precipitating, then adds in precipitating gained The water for entering to precipitate 5-15 times of quality continues to be placed in decocting 1-4 hours at 95-98 DEG C, obtains the second decoction liquor, merges and decocts for the first time Boil liquid and the second decoction liquor, stand, centrifugation, old brown sugar is then added into gained supernatant, be first placed in after mixing 85-95 DEG C, 1-5h is concentrated under conditions of being 0.05-0.07MPa in absolute pressure, is then placed in 55-65 DEG C, absolute pressure 0.05-0.07MPa Under conditions of be concentrated into relative density be 1.03-1.10, be finally placed in 50-70 DEG C of infrared drier and be concentrated into relative density For 1.20-1.25, ferine honey is added after being cooled to 40-55 DEG C, mixes, it is cooling, it is canned, packaging to get.
Preferably, in the manufacture craft for stating menstruction regulating and pain relieving red date-walnut drink, the cryogenic temperature control in the step I exists Subzero 170 DEG C -100 DEG C subzero, thaw point is controlled at 20-35 DEG C.
By adopting the above-described technical solution, compared with prior art, the present invention has the following advantages: the present invention with Motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, walnut, jujube, radix rehmanniae preparata, semen sojae atricolor, old brown sugar, ferine honey are raw material, By the preparation of reasonable compatibility and science, the menstruction regulating and pain relieving red date-walnut drink being prepared is adjusting endocrine disorder, is solving Menstruation postponement, blood stasis, amount are less, palace cold, color are dark, dysmenorrhea, premenstrual swollen breasts, paramenia, pregnancy difficulty, pregnant preceding menstruation regulating, support Palace, warm palace etc., have a good effects, and can activating microcirculation and removing stasis medicinal, delay menopause, additionally aid production and post-abortion miscellaneous disease and son Palace, which is supported, waits shield, has a vast market foreground.
Specific embodiment
Foregoing invention content of the invention is described in further detail With reference to embodiment, but should not be incited somebody to action This range for being interpreted as the above-mentioned theme of the present invention is only limitted to following embodiments.
Each raw material and equipment introduction in embodiment:
Motherwort, Classification system: Leonurus artemisia (Laur.) S.Y.Hu F plants for Labiatae mother wort Co., Ltd is sold purchased from the great Chinese medicine of Bozhou City Sai Er in object, place of production Anhui.
Radix Salviae Miltiorrhizae, Classification system: Salvia miltiorrhiza Bge. is the dry root and root of Lamiaceae plant Radix Salviae Miltiorrhizae Co., Ltd is sold purchased from the great Chinese medicine of Bozhou City Sai Er in stem, place of production Shandong.
Radix Angelicae Sinensis, Classification system: Angelica pubescens Maxim.f.biserrata Shan et Yuan is umbrella The dry root of shape section plant Angelica pubescens, place of production Gansu are purchased from Chengdu moral sounds electronic commercial affairs Co., Ltd.
Safflower, Classification system: Carthamus tinctorius L. produces for the tubular flower that composite family safflower plant is dry Ground Xinjiang, the great Chinese medicine of Bozhou City Sai Er sell Co., Ltd.
China rose, Classification system: Rosa chinensis Jacq. is the dry flower of rosaceous plant Chinese rose, place of production river North is purchased from the mill Anguo City Yu Yan Chinese medicine Co., Ltd.
Walnut, Classification system: Juglans regia L., is Juglandaceae walnut, and kind kernel walnut is purchased from Shan Xi Wangfeng Agricultural Products Trade Co., Ltd.
Jujube, Classification system: Ziziphus jujuba Mill.var.inermis (Bunge) Rehd. is Rhamnaceae jujube The dry mature fruit of platymiscium jujube, kind Ruoqiang ash jujube are purchased from Linyi Yang Min commerce and trade Co., Ltd.
Radix rehmanniae preparata, Classification system: Rehmannia glutinosa is the root tuber of scrophulariaceae rehmannia glutinosa plant, place of production Guangdong, purchase Medicinal material row is begged from Bozhou City man.
Semen sojae atricolor, Classification system: Glycinemax (L.) merr, is the black seeds of legume soybean, and kind Luzhou City is black Beans are purchased from Hefei Zheng Guang Agricultural Products Trade Co., Ltd.
Old brown sugar is purchased from Lincang Jun Wo Biotechnology Co., Ltd.
Ferine honey, honey category are honey of various flowers, are purchased from the city Luo Yang, the garden Jian Feng bee product shop, Chan river reach.
Kelp, Classification system: Laminaria japonica, is Laminariaceae kelp platymiscium, and place of production Fujian is purchased from Fujian Save three husky fishery Co., Ltds.
Salt algae, Classification system: Dunaliella salina, is Chlorophyceae Yan Zao section plant, and place of production Liaoning is purchased from Dalian Feng Yuan bait Co., Ltd.
Seaweed, Classification system: Porphyra, is Rhodophyceae Bangiales section plant, and place of production Jiangsu is purple purchased from the good reputation in Lianyun Harbour Dish processes Co., Ltd.
Supersonic jet mill uses the YQ100 type supersonic gas of Shanghai Sai Shan powder machinery Manufacturing Co., Ltd production Flow pulverizer.
Medium and short-wave infrared drying machine is STC type medium and short-wave infrared drying equipment, limited purchased from the infrared science and technology of Qin state Sheng Taike Company.
Reaction pot is WKT-50 type Chinese medicine reaction pot, is purchased from Shandong absolute sincerity medicine equipment manufacturing Co., Ltd.(can steam, boil, Extraction, concentrated traditional Chinese medicine)
Centrifugation apparatus founds the LD4-8 type low speed centrifuge of centrifuge Co., Ltd offer using system in Beijing Jing.
Bag filter, material are cellulose, and diameter 7.5mm flattens width 12mm, molecular cut off 8000Da, model For MD12, it is purchased from Nanjing Sen Beijia Biotechnology Co., Ltd.
Vacuum freeze is FD-100S type vacuum freeze drier, purchased from the limited public affairs of the good instrument science and technology of Beijing Hui Cheng Department.
Embodiment 1
A kind of menstruction regulating and pain relieving red date-walnut drink is made of following mass parts raw materials: 5 parts of walnut, 5 parts of jujube, motherwort 18 Part, 9 parts of Radix Salviae Miltiorrhizae, 9 parts of Radix Angelicae Sinensis, 9 parts of safflower, 9 parts of radix rehmanniae preparata, 9 parts of China rose, 5 parts of semen sojae atricolor, 9 parts of old brown sugar, 5 parts of ferine honey.
The manufacture craft of the menstruction regulating and pain relieving red date-walnut drink, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, is mixed Mixture, is then put into reaction pot by material, and 8 times of mixture quality of distilled water is added, is placed at 25 DEG C and impregnates 3 hours, take The raw material of immersion treatment is obtained after out;
The raw material of immersion treatment is placed in reaction pot by II, and 8 times of material quality of distilled water of immersion treatment is added, is placed in Decocted 2 hours at 95 DEG C, after 400 mesh filter-cloth filterings, obtain first time decoction liquor and material residue, then to will in material residue be added material The distilled water that 8 times of slag amount continues to be placed in decocting 2 hours at 95 DEG C, obtains the second decoction liquor, merges first time decoction liquor and the Two decoction liquors are placed at 25 DEG C and stand 12 hours, after 400 mesh filter-cloth filterings, old brown sugar is then added into gained filtered fluid, 30min is stirred under conditions of 20 DEG C, 200r/min, being placed in tanning at 85 DEG C and arriving relative density is 1.25, it is cooling, it is cooled to 50 Ferine honey is added after DEG C, stirs 30min under conditions of 60 DEG C, 200r/min, is cooled to 20 DEG C, it is canned, packaging to get.
Embodiment 2
A kind of menstruction regulating and pain relieving red date-walnut drink is made of following mass parts raw materials: 5 parts of walnut, 5 parts of jujube, motherwort 18 Part, is answered at 9 parts of Radix Salviae Miltiorrhizae, 9 parts of Radix Angelicae Sinensis, 9 parts of safflower, 9 parts of radix rehmanniae preparata, 9 parts of China rose, 5 parts of semen sojae atricolor, 9 parts of old brown sugar, 5 parts of ferine honey Close 0.6 part of polysaccharide composition.
The complex polysaccharide is mixed by laminarin, polysaccharide from Dunaliella salina, laver amylose by the mass ratio of 1:1:1.
The laminarin the preparation method comprises the following steps:
I, which cleans kelp, is placed on drying 5 hours at 55 DEG C, is crushed to 40 mesh, obtains pretreated raw material;With pretreatment The pretreated raw material of distilled water immersion 2 hours of 10 times of quality of raw material, obtain soak, water-bath is heated to impregnating at 90 DEG C After the 30% of liquid product, 30% 6wt% solution of trichloroacetic acid of soak volume is added, 12 hours are stood at 4 DEG C, 4 DEG C, be centrifugated 30min under conditions of 2500r/min, 1.5 times of supernatant quality of ethyl alcohol is added into gained supernatant, 20 DEG C, stir 30min under conditions of 200r/min, stand 12 hours at 4 DEG C, continue under conditions of 4 DEG C, 2500r/min It is centrifugated 30min, is precipitated after removing supernatant, the distilled water dissolution of 1.5 times of quality of precipitating is added, then carries out vacuum Freeze-drying process, the condition of vacuum freeze drying are that control material thickness is 10mm, set pre-freezing temperature as subzero 40 DEG C, when Sample temperature is kept for 2 hours after dropping to set temperature, sets sublimation temperature as 10 DEG C, resolution temperature is 35 DEG C, and absolute pressure is 30Pa, dry 30h, obtains Thick many candies;
5 times of Thick many candies quality of distilled water is added into above-mentioned Thick many candies by II, stirs under conditions of 20 DEG C, 200r/min After mixing 30min, in the bag filter that is loaded on, entire bag filter is totally immersed into distilled water, is dialysed 60 hours at 4 DEG C, every 12h Primary distilled water is changed, acquired solution carries out vacuum freeze drying, and the condition of vacuum freeze drying is control material thickness 8mm, if Determining pre-freezing temperature is subzero 20 DEG C, when holding 1.5 is small after sample temperature drops to -20 DEG C, sets sublimation temperature as 12 DEG C, parses Temperature is 34 DEG C, absolute pressure 30Pa, dry 24 hours to get.
The preparation method of the polysaccharide from Dunaliella salina and the preparation method of the laminarin are essentially identical, only replace with kelp Salt algae.
The preparation method of the laver amylose and the preparation method of the laminarin are essentially identical, only replace with kelp Seaweed.
The manufacture craft of the menstruction regulating and pain relieving red date-walnut drink, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, is mixed Mixture, is then put into reaction pot by material, and 8 times of mixture quality of distilled water is added, is placed at 25 DEG C and impregnates 3 hours, obtain To the raw material of immersion treatment;
The raw material of immersion treatment, complex polysaccharide composition are placed in reaction pot by II, and the material quality 8 of immersion treatment is added Distilled water again, is placed at 95 DEG C and decocts 2 hours, after 400 mesh filter-cloth filterings, obtain first time decoction liquor and material residue, then To by the distilled water of 8 times of material residue quality of addition in material residue, continue to be placed in decocting 2 hours at 95 DEG C, obtain the second decoction liquor, merges First time decoction liquor and the second decoction liquor are placed at 25 DEG C and stand 12 hours, after 400 mesh filter-cloth filterings, then to gained mistake Old brown sugar is added in filtrate, stirs 30min under conditions of 20 DEG C, 200r/min, being placed at 85 DEG C tanning to relative density is 1.25, it is cooling, ferine honey is added after being cooled to 50 DEG C, stirs 30min under conditions of 60 DEG C, 200r/min, is cooled to 20 DEG C, it is canned, packaging to get.
Embodiment 3
Substantially the same manner as Example 2, difference is only in that: the complex polysaccharide is by laminarin, polysaccharide from Dunaliella salina by 1:1's Mass ratio mixing.
Embodiment 4
Substantially the same manner as Example 2, difference is only in that: the complex polysaccharide is by polysaccharide from Dunaliella salina, laver amylose by 1:1's Mass ratio mixing.
Embodiment 5
Substantially the same manner as Example 2, difference is only in that: the complex polysaccharide is by laminarin, laver amylose by 1:1's Mass ratio mixing.
Embodiment 6
Substantially the same manner as Example 2, difference is only in that: the manufacture craft of the menstruction regulating and pain relieving red date-walnut drink, including Following step:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, is mixed Material is placed in subzero 10 DEG C, carries out supersonic airstream broken wall treatment under conditions of 1400r/min, 200 mesh is crushed to, then zero 1h is freezed at lower 170 DEG C, is subsequently placed at 25 DEG C and places 6h, then 1h is freezed at subzero 170 DEG C again, is finally placed at 25 DEG C 6h is placed, raw material powder is obtained;
Raw material powder, complex polysaccharide composition are placed in reaction pot by II, and 8 times of raw material powder quality of distilled water is added, sets It is decocted 2 hours at 95 DEG C, is centrifugated 30min under conditions of 20 DEG C, 2500r/min, obtain first time decoction liquor and sunk It forms sediment, the distilled water of 8 times of quality of precipitating is then added in precipitating gained, continues to be placed in decocting 2 hours at 95 DEG C, obtains second Decoction liquor merges first time decoction liquor and the second decoction liquor, is placed at 25 DEG C and stands 12 hours, in 20 DEG C, the item of 2500r/min Continue to be centrifugated 30min under part, old brown sugar is then added into gained supernatant, is stirred under conditions of 20 DEG C, 200r/min Mix 30min, be placed at 85 DEG C tanning to relative density be 1.25, it is cooling, ferine honey is added after being cooled to 50 DEG C, 60 DEG C, Stir 30min under conditions of 200r/min, be cooled to 20 DEG C, it is canned, packaging to get.
Embodiment 7
Substantially the same manner as Example 2, difference is only in that: the manufacture craft of the menstruction regulating and pain relieving red date-walnut drink, including Following step:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, is mixed Material is placed in subzero 10 DEG C, carries out supersonic airstream broken wall treatment under conditions of 1400r/min, 200 mesh is crushed to, then zero 1h is freezed at lower 170 DEG C, is subsequently placed at 25 DEG C and places 6h, then 1h is freezed at subzero 170 DEG C again, is finally placed at 25 DEG C 6h is placed, raw material powder is obtained;
Raw material powder, complex polysaccharide composition are placed in reaction pot by II, and 8 times of raw material powder quality of distilled water is added, sets It is decocted 2 hours at 95 DEG C, is centrifugated 30min under conditions of 20 DEG C, 2500r/min, obtain first time decoction liquor and sunk It forms sediment, the distilled water of 8 times of quality of precipitating is then added in precipitating gained, continues to be placed in decocting 2 hours at 95 DEG C, obtains second Decoction liquor merges first time decoction liquor and the second decoction liquor, is placed at 25 DEG C and stands 12 hours, in 20 DEG C, the item of 2500r/min Continue to be centrifugated 30min under part, old brown sugar is then added into gained supernatant, is stirred under conditions of 20 DEG C, 200r/min Mix 30min, be first placed in 90 DEG C, absolute pressure be 0.05MPa under conditions of 2h is concentrated, be then placed in 55 DEG C, absolute pressure be It is 1.05 that relative density is concentrated under conditions of 0.05MPa, is finally placed in 70 DEG C of infrared drier, the infrared drier Power be 1125W, wind speed 4.5m/s, dry to relative density is 1.25, ferine honey is added after being cooled to 50 DEG C, 20 DEG C, stir 30min under conditions of 200r/min, be cooled to 20 DEG C, canned, packaging.
Test case 1
Antioxidant effect test: referring in Luo Shengyong " anti-senile medicine cream delaying senility function and its Mechanism Study " 1.4 sections Test method detects the antioxidant effect of menstruction regulating and pain relieving red date-walnut drink of the present invention.Specific experiment method: this test case SPF grade ICR mouse (be purchased from Zhejiang University of Traditional Chinese Medicine animal experiment study center) of the selection weight in 20 ± 2g, half male and half female, 8 groups are randomly divided into, every group of 10 mouse, the 1st group is blank group, the physiological saline of daily stomach-filling 0.5mL, the filling daily of 2-8 group The menstruction regulating and pain relieving red date-walnut drink of the present invention of stomach 0.5mL after continuous 3 weeks, after last stomach-filling 1h, takes blood in animal eyeball and locates Dead animal measures SOD, GSH-Px content and activity in serum, compares each group and blank group test result, pass through statistical analysis Method obtains P < 0.05, shows that sample average difference has statistical significance, specific test result is shown in Table 1.
Table 1: antioxidant effect test result table
Group SOD/(U/mL) GSH-Px/(U/mL)
Blank group 391.55 239.40
Embodiment 1 434.21 260.46
Embodiment 2 537.49 322.01
Embodiment 3 460.71 276.09
Embodiment 4 450.81 281.51
Embodiment 5 456.55 283.38
Embodiment 6 575.88 345.76
Embodiment 7 614.27 368.63
By test result it is found that complex polysaccharide composition is mixed by laminarin, polysaccharide from Dunaliella salina, laver amylose in embodiment 2 It closes, antioxidant effect better than embodiment 3-5, (appointed by laminarin, polysaccharide from Dunaliella salina, laver amylose by complex polysaccharide composition Anticipate two kinds and form) and it is not added with the embodiment 1 of complex polysaccharide composition.
Test case 2
Influence to primary dysmenorrhea model mice: menstruction regulating and pain relieving red date-walnut drink of the present invention is investigated to primary dysmenorrhea mould The influence of type mouse.
Specific experiment method: this test case chooses weight in the ICR mouse of the female unpregnancy of 20 ± 2g, and SPF grades (are purchased from Zhejiang River university of TCM animal experiment study center), 8 groups are randomly divided into, every group of 10 mouse, the 1st group is model control group, daily The physiological saline of stomach-filling 0.5g, the menstruction regulating and pain relieving red date-walnut drink of the present invention of the daily stomach-filling 0.5g of 2-8 group, continuous gavage 6 days Afterwards;It gives the diethylstilbestrol of every mouse subcutaneous injection 0.2mg/kg simultaneously on day 4, after the last administration 30min, injects contracting palace Element refers to reference to 1.5 sections experiment in Wu Li " Paeoniflorin, albiflorin act on the spasmolysis and analgesia of primary dysmenorrhea model mice " Detection method is marked, records and calculates after injection that incubation period and the writhing number of writhing occur for the first time for mouse in 40min.Compare each Group and model control group test result, obtain P < 0.05 by statistical analysis method, show that sample average difference has statistics Meaning, specific test result are shown in Table 2.
Table 2: the influence to primary dysmenorrhea model mice
Group Incubation period/min Writhing number
Model control group 3.9 40
Embodiment 1 4.3 36
Embodiment 2 5.6 27
Embodiment 3 4.7 29
Embodiment 4 5.0 32
Embodiment 5 4.9 30
Embodiment 6 7.2 22
Embodiment 7 8.4 19
By test result it is found that the menstruction regulating and pain relieving red date-walnut drink obtained using manufacture craft in embodiment 6, relative to reality For applying example 2, the prolongation of latency of writhing occurs for mouse, and the number that writhing response occurs also is reduced;And embodiment 7 is used to make Make menstruction regulating and pain relieving red date-walnut drink, further extends mouse and the incubation period of writhing occurs and reduces writhing number occurs.
Test case 3
Analgesic evaluation: 12-30 years old female volunteers are chosen, are randomly divided into 7 groups, every group of 10 people, volunteer there should be dysmenorrhea Symptom, Yu Yuejing the last week, Yu Yuejing the last week start to menstruation after coming three days, and it is red to take menstruction regulating and pain relieving of the present invention respectively Jujube walnut drink, is taken twice daily, and once takes 10g, continuously takes three menstrual cycles, and every using effect total score is 5 points: 5 points are best result, are indicated very well, very satisfied;4 points are preferable;3 points are that can receive;3 points the following are bad, cannot receive. Compare each group test result, P < 0.05 obtained by statistical analysis method, shows that sample average difference has statistical significance, Specific test result is shown in Table 3.
Table 3: analgesic evaluation test result table
By test result it is found that menstruction regulating and pain relieving red date-walnut drink of the present invention has preferable activating microcirculation and removing stasis medicinal, enriches blood, relieves pain Effect.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore The equivalent or simple change that all principles described according to the invention patent design are done, is included in the scope of protection of the patent of the present invention It is interior;Those skilled in the art can make various modifications or additions to the described embodiments Or be substituted in a similar manner, without departing from structure of the invention or beyond the scope defined by this claim, It is within the scope of protection of the invention.

Claims (8)

1. a kind of menstruction regulating and pain relieving red date-walnut drink, which is characterized in that its raw material is in parts by mass, comprising: 4-6 parts of walnut, jujube 4-6 parts, 15-20 parts of motherwort, 8-10 parts of Radix Salviae Miltiorrhizae, 8-10 parts of Radix Angelicae Sinensis, 8-10 parts of safflower, 8-10 parts of radix rehmanniae preparata, 8-10 parts of China rose, 4-6 parts of semen sojae atricolor, it is brown sugar 8-10 parts old, 4-6 parts of ferine honey.
2. a kind of menstruction regulating and pain relieving red date-walnut drink, which is characterized in that its raw material is in parts by mass, comprising: 4-6 parts of walnut, jujube 4-6 parts, 15-20 parts of motherwort, 8-10 parts of Radix Salviae Miltiorrhizae, 8-10 parts of Radix Angelicae Sinensis, 8-10 parts of safflower, 8-10 parts of radix rehmanniae preparata, 8-10 parts of China rose, 4-6 parts of semen sojae atricolor, brown sugar 8-10 parts old, 4-6 parts of ferine honey, 0.5-1.5 parts of complex polysaccharide composition.
3. menstruction regulating and pain relieving red date-walnut drink as claimed in claim 2, which is characterized in that the complex polysaccharide composition includes kelp One of polysaccharide, polysaccharide from Dunaliella salina, laver amylose are a variety of.
4. menstruction regulating and pain relieving red date-walnut drink as claimed in claim 3, which is characterized in that the laminarin the preparation method comprises the following steps:
Kelp is cleaned to be placed at 55-60 DEG C and dry, pulverize by I, obtains pretreated raw material;Pretreated raw material is placed in water Middle immersion 2-6 hours, obtains soak, after water-bath is heated to the 20-40% of soak volume at 85-95 DEG C, is added and impregnates The 3-6wt% solution of trichloroacetic acid of the 20-40% of liquid product, stands 12-16 hours at 2-5 DEG C, is centrifuged, to gained supernatant The middle ethyl alcohol that 1-3 times of supernatant quality is added, stirs evenly, and is centrifuged, and is precipitated after removing supernatant, after water dissolution is added, Vacuum freeze drying processing, obtains Thick many candies;
The water of 5-15 times of Thick many candies quality is added into above-mentioned Thick many candies by II, dialyses 60-120 hours at 2-5 DEG C, every 6-12h Change a water, acquired solution through vacuum freeze drying to get.
5. menstruction regulating and pain relieving red date-walnut drink as claimed in claim 2, which is characterized in that the system of the menstruction regulating and pain relieving red date-walnut drink Make technique, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, obtains mixture, Mixture is put into reaction pot, 5-15 times of mixture quality of water is added, is placed at 25-35 DEG C and impregnates 2-5 hours, after taking-up Obtain the raw material of immersion treatment;
The raw material of immersion treatment, complex polysaccharide composition are placed in reaction pot by II, and 5-15 times of material quality of immersion treatment is added Water, be placed at 95-98 DEG C and decoct 1-4 hours, filter, obtain first time decoction liquor and material residue, then to will be added in material residue The water of 5-15 times of material residue quality continues to be placed in decocting 1-4 hours at 95-98 DEG C, obtains the second decoction liquor, merges and decocts for the first time Liquid and the second decoction liquor are stood, filtering, and old brown sugar is then added into gained filtered fluid, and mixing, which is placed at 85-95 DEG C, to be boiled It is cooling to relative density 1.21-1.25, ferine honey is added after being cooled to 40-55 DEG C, mixes, cooling, canned, packaging, i.e., ?.
6. menstruction regulating and pain relieving red date-walnut drink as claimed in claim 2, which is characterized in that the system of the menstruction regulating and pain relieving red date-walnut drink Make technique, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, obtains mixture, It is placed in progress supersonic airstream broken wall treatment at subzero 8 DEG C of subzero 10-, after being crushed to 200-600 mesh, freezing 1-3 hours, then It defrosting 3-6 hours, then freezes 1-3 hours, finally defrosting 3-6 hours, obtains raw material powder;
Raw material powder, complex polysaccharide composition are placed in reaction pot by II, and the water of 5-15 times of raw material powder quality is added, is placed in 95- It is decocted 1-4 hours at 98 DEG C, is centrifuged, obtains first time decoction liquor and precipitating, precipitating quality is then added in precipitating gained 5-15 times of water continues to be placed in decocting 1-4 hours at 95-98 DEG C, obtains the second decoction liquor, merges first time decoction liquor and second Decoction liquor is stood, centrifugation, and old brown sugar is then added into gained supernatant, and mixing is placed at 85-95 DEG C and boils to relatively close Spend 1.21-1.25, it is cooling, ferine honey is added after being cooled to 40-55 DEG C, mixes, it is cooling, it is canned, packaging to get.
7. menstruction regulating and pain relieving red date-walnut drink as claimed in claim 2, which is characterized in that the system of the menstruction regulating and pain relieving red date-walnut drink Make technique, includes the following steps:
I, first mixes walnut, jujube, motherwort, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, China rose, semen sojae atricolor, obtains mixture, It is placed in progress supersonic airstream broken wall treatment at subzero 8 DEG C of subzero 10-, after being crushed to 200-600 mesh, freezing 1-3 hours, then It defrosting 3-6 hours, then freezes 1-3 hours, finally defrosting 3-6 hours, obtains raw material powder;
Raw material powder, complex polysaccharide composition are placed in reaction pot by II, and the water of 5-15 times of raw material powder quality is added, is placed in 95- It is decocted 1-4 hours at 98 DEG C, is centrifuged, obtains first time decoction liquor and precipitating, precipitating quality is then added in precipitating gained 5-15 times of water continues to be placed in decocting 1-4 hours at 95-98 DEG C, obtains the second decoction liquor, merges first time decoction liquor and second Decoction liquor, stand, centrifugation, old brown sugar is then added into gained supernatant, be first placed in after mixing 85-95 DEG C, absolute pressure be 1-5h is concentrated under conditions of 0.05-0.07MPa, be then placed in 55-65 DEG C, absolute pressure be 0.05-0.07MPa under conditions of it is dense Being reduced to relative density is 1.03-1.10, and being finally placed in 50-70 DEG C of infrared drier and being concentrated into relative density is 1.20- 1.25, ferine honey is added after being cooled to 40-55 DEG C, mixes, it is cooling, it is canned, packaging to get.
8. menstruction regulating and pain relieving red date-walnut drink as claimed in claims 6 or 7, which is characterized in that the menstruction regulating and pain relieving red date-walnut drink Manufacture craft in, the control of cryogenic temperature in the step I subzero 170 DEG C-it is 100 DEG C subzero, thaw point is controlled in 20- 35℃。
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Application publication date: 20190419