CN109601993A - 一种补肾益气养血安神滋补膏及其制备工艺 - Google Patents
一种补肾益气养血安神滋补膏及其制备工艺 Download PDFInfo
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Abstract
本发明公开了一种补肾益气养血安神滋补膏及其制备工艺,主要包括一下原料:甘草、人参、枣仁、红枣、莲米、百合、龙眼肉、牡蛎、雪莲、山药、生姜、蜂蜜、黄秋葵、杜仲雄花、诺丽果、黑豆、蛹虫草、阿胶、蓝莓、枸杞子、地龙蛋白、沙棘。上述原料经过合理配比,使药物中各种有效成分相互配合,采用纯中药组方,不添加任何化学药物,制作工艺中采用红外线烘烤技术,在消灭病菌的同时使得药物中的有效化学成分充分释放,改善人体微循环,更易于人体吸收,补肾益气效果更好。
Description
技术领域
本发明涉及保健食品领域,尤其涉及一种补肾益气养血安神滋补膏及其制备工艺。
背景技术
随着现代生活水平的不断发展,人们所面临的压力也越来越大,从而导致身体机能出现一系列的问题,中医基础理论指出:肾位于腰部,脊柱两侧,左右各一,其主要功能是藏精,主人体生长、发育与生殖。肾虚的症状:肾阳虚的症状为腰酸、四肢发冷、畏寒,甚至还有水肿,为“寒”的症状,性功能不好也会导致肾阳虚;肾阴虚的症状为“热”,主要有腰酸、燥热、盗汗、虚汗、头晕、耳鸣等。现代科学证明,当人发生肾虚时,无论肾阴虚还是肾阳虚,都会导致人的免疫能力的降低,有更多的证据表明,肾虚发生时,肾脏的免疫能力降低,而肾脏的微循环系统亦会发生阻塞,肾络呈现不通。
针对肾虚、气血不足的现象,人们大多会采用喝中药的方式进行调理,但是中药汤一般只是经过煎煮,口感苦涩,难以下咽;现如今市面上出现了一些中药膏,但是这些中药膏仅仅通过简单的熬制、冷却等工艺加工而成,配料中的有效成分不能充分释放,不利于人体的吸收,疗效不明显;同时一些中药膏还加入了某些化学药剂,具有毒副作用。
发明内容
为解决上述问题,本发明提出一种补肾益气养血安神滋补膏及其制备工艺。
为实现本发明目的,采用的技术方案是:
一种补肾益气养血安神滋补膏,原材料按照如下份数比组成:甘草8-12份、人参3-5份、枣仁4-7份、红枣6-10份、莲米2-5份、百合0.5-2份、龙眼肉7-10份、牡蛎3-5份、雪莲1-3份、山药1-3份、生姜2-3份、蜂蜜3-4份、黄秋葵4-6份、杜仲雄花1-4份、诺丽果3-5份、黑豆4-7份、蛹虫草3-5份、阿胶13-17份、蓝莓4-5份、枸杞子2-4份、地龙蛋白2-4份、沙棘2-3份。
优选的,制备方法如下:
(1)取甘草、人参、龙眼肉进行灭菌处理;
(2)将雪莲、百合、莲米、牡蛎用红外线烘烤,360W焙烤6min;
(3)将蛹虫草进行干燥处理,干燥后蛹虫草含水量为(5±1)%,干燥完成后粉碎过160目筛制成蛹虫草粉;
(4)将甘草、人参、龙眼肉、雪莲、百合、莲米、牡蛎与8倍质量的水进行加热煎煮,煎煮时间为2-3h,取上清液备用;
(5)将步骤(3)中的蛹虫草粉与步骤(4)中煎煮得到的上清液在69-75℃条件下搅拌,混合均匀,得到初配液;
(6)将步骤(5)中的初配液与处理干净的山药、生姜、黄秋葵、杜仲雄花、诺丽果、黑豆、蓝莓、枸杞子、沙棘以及9倍质量的水进行加热煎煮4-5h,浓缩成相对密度为2.6-2.8的粘稠液;
(7)将阿胶、地龙蛋白进行粉碎处理,过200目筛制成混合粉;
(8)将步骤(6)得到的粘稠液、步骤(7)中的阿胶、地龙蛋白混合粉以及蜂蜜混合,搅拌均匀成膏状。
优选的,所述步骤(3)蛹虫草进行干燥处理的温度为60-85℃。
优选的,所述步骤(4)中将加热煎煮温度为120-125℃。
本发明的有益效果如下:
1.本发明是按照“君臣佐使”的原则,对组方配伍中的化学成分、药理作用、功能效果、常用剂量进行了合理配比,甘草中含有甘草甜素、甘草次酸、甘草醇、异甘草醇、香豆素、生物碱等多种有效成分,味甘、性平,有补脾益气调和诸药的功能;人参含有人参皂甙、挥发油、有机酸及酯类、含氮化合物、甾醇及其甙类、腺苷转化酶、L-天冬氨酸酶、β-淀粉酶、蔗糖转化酶,味甘微寒,主补五脏;龙眼肉性甘、温,可补益心脾、养血安神,用于治疗气血不足,心悸怔忡,健忘失眠,血虚萎黄等症;从蛹虫草中活性成分包括腺虫草素、腺嘌呤、腺苷、肌苷、胸腺嘧啶、次黄嘌呤等;本发明合理搭配使药物中各种有效成分相互配合,滋补肝肾,益气养血,可有效解决肝肾不足引起的神疲乏力,头昏耳鸣,腰膝酸软,夜尿频多。具有调理月经痛经、祛斑防皱、治疗便秘、美容养颜功效,补肾益气效果更好。
2、对蛹虫草进行干燥处理时,干燥温度为60-85℃,最终含水量为(5±1)%,此时蛹虫草中含有的超氧化歧化酶的热稳定性较高,在含水量为(5±1)%时,超氧化歧化酶的酶活性比较稳定;同时,激发蛹虫草中的纤维蛋白溶解酶的最大活性,吸收各种物质的效率更高,更易于人体吸收。
3、采用纯中药组方,不添加任何化学药物,对人体没有毒副作用。
4、制作工艺中采用红外线烘烤技术,在消灭病菌的同时引起分子共振,使表面水分迅速挥发,使得雪莲、百合、莲米、牡蛎内外湿度梯度增大,有效巩固黄酮类化合物、萜类及其衍生物、豆甾烷醇、β-谷甾醇、牛蒡苷元等物质的结构,避免在后续混合过程中被破坏,而降低补肾益气功效;同时可抑制自由基的生成,阻断自由基对机体的过氧化作用,增强清除超氧阴离子自由基和抗NADH过氧化物酶氧化的能力,从而增强美容养颜功效。
5、对诺丽果加热煎煮时为4-5h,此时诺丽果中的赛洛宁会与人体内的蛋白质结合,生成复合胺,复合胺在人体血液中发挥重要作用,促进细胞再生,并且可以令体内受损的细胞及组织重新活跃起来,改善体质,益气补血。
具体实施方式
下面将结合具体实施例对本发明的技术方案进行清楚、完整地描述。
实施例1:
一种补肾益气养血安神滋补膏,原材料按照如下份数比组成:甘草9份、人参4份、枣仁5份、红枣8份、莲米4份、百合0.5份、龙眼肉8份、牡蛎4份、雪莲2份、山药1.5份、生姜2份、蜂蜜4份、黄秋葵6份、杜仲雄花3份、诺丽果4份、黑豆4份、蛹虫草4份、阿胶14份、蓝莓4份、枸杞子2份、地龙蛋白4份、沙棘3份。
补肾益气养血安神滋补膏的制备方法如下:
(1)取甘草、人参、龙眼肉进行灭菌处理;
(2)将雪莲、百合、莲米、牡蛎用红外线烘烤,360W焙烤6min;
(3)将蛹虫草进行干燥处理,温度为60℃,干燥完成后粉碎过160目筛制成蛹虫草粉,蛹虫草含水量为4%;
(4)将甘草、人参、龙眼肉、雪莲、百合、莲米、牡蛎与8倍质量的水进行加热煎煮,加热煎煮温度为120℃煎煮时间为2h,取上清液备用;
(5)将步骤(3)中的蛹虫草粉与步骤(4)中煎煮得到的上清液在70℃条件下搅拌,混合均匀,得到初配液;
(6)将步骤(5)中的初配液与处理干净的山药、生姜、黄秋葵、杜仲雄花、诺丽果、黑豆、蓝莓、枸杞子、沙棘以及9倍质量的水进行加热煎煮4h,浓缩成相对密度为2.6的粘稠液;
(7)将阿胶、地龙蛋白进行粉碎处理,过200目筛制成混合粉;
(8)将步骤(6)得到的粘稠液、步骤(7)中的阿胶、地龙蛋白混合粉以及蜂蜜混合,搅拌均匀成膏状。
实施例2:
一种补肾益气养血安神滋补膏,原材料按照如下份数比组成:甘草11份、人参3份、枣仁4份、红枣10份、莲米2份、百合0.5份、龙眼肉8份、牡蛎3份、雪莲3份、山药1.5份、生姜2份、蜂蜜3份、黄秋葵6份、杜仲雄花2份、诺丽果4份、黑豆4份、蛹虫草4份、阿胶16份、蓝莓4份、枸杞子3份、地龙蛋白2份、沙棘2份。
补肾益气养血安神滋补膏的制备方法如下:
(1)取甘草、人参、龙眼肉进行灭菌处理;
(2)将雪莲、百合、莲米、牡蛎用红外线烘烤,360W焙烤6min;
(3)将蛹虫草进行干燥处理,温度为70℃,干燥完成后粉碎过160目筛制成蛹虫草粉,蛹虫草含水量为5%;
(4)将甘草、人参、龙眼肉、雪莲、百合、莲米、牡蛎与8倍质量的水进行加热煎煮,加热煎煮温度为123℃煎煮时间为2.5h,取上清液备用;
(5)将步骤(3)中的蛹虫草粉与步骤(4)中煎煮得到的上清液在73℃条件下搅拌,混合均匀,得到初配液;
(6)将步骤(5)中的初配液与处理干净的山药、生姜、黄秋葵、杜仲雄花、诺丽果、黑豆、蓝莓、枸杞子、沙棘以及9倍质量的水进行加热煎煮4.5h,浓缩成相对密度为2.7的粘稠液;
(7)将阿胶、地龙蛋白进行粉碎处理,过200目筛制成混合粉;
(8)将步骤(6)得到的粘稠液、步骤(7)中的阿胶、地龙蛋白混合粉以及蜂蜜混合,搅拌均匀成膏状。
实施例3:
一种补肾益气养血安神滋补膏,原材料按照如下份数比组成:
甘草10份、人参3份、枣仁7份、红枣6份、莲米3份、百合1份、龙眼肉10份、牡蛎4份、雪莲2份、山药2.5份、生姜2份、蜂蜜4份、黄秋葵5份、杜仲雄花3份、诺丽果3份、黑豆5份、蛹虫草3份、阿胶13份、蓝莓4份、枸杞子2份、地龙蛋白4份、沙棘3份。
补肾益气养血安神滋补膏的制备方法如下:
(1)取甘草、人参、龙眼肉进行灭菌处理;
(2)将雪莲、百合、莲米、牡蛎用红外线烘烤,360W焙烤6min;
(3)将蛹虫草进行干燥处理,温度为85℃,干燥完成后粉碎过160目筛制成蛹虫草粉,蛹虫草含水量6%;
(4)将甘草、人参、龙眼肉、雪莲、百合、莲米、牡蛎与8倍质量的水进行加热煎煮,加热煎煮温度为125℃煎煮时间为3h,取上清液备用;
(5)将步骤(3)中的蛹虫草粉与步骤(4)中煎煮得到的上清液在75℃条件下搅拌,混合均匀,得到初配液;
(6)将步骤(5)中的初配液与处理干净的山药、生姜、黄秋葵、杜仲雄花、诺丽果、黑豆、蓝莓、枸杞子、沙棘以及9倍质量的水进行加热煎煮5h,浓缩成相对密度为2.8的粘稠液;
(7)将阿胶、地龙蛋白进行粉碎处理,过200目筛制成混合粉;
(8)将步骤(6)得到的粘稠液、步骤(7)中的阿胶、地龙蛋白混合粉以及蜂蜜混合,搅拌均匀成膏状。
实施例4:效果实验
采用自愿原则,选取具有肾虚贫血、气弱血虚、心悸不安、失眠多梦以及皮肤干燥、毛发枯黄、体质虚弱等亚健康现象的志愿者120例,每组20例,实验组每天早晚服用实施例1-3所制得的补肾益气养血安神滋补膏,对照组每天服用中药汤剂,所述中药汤剂为与实施例1-3中具有相同份数比的配方,不同之处在于对照组中的中药汤剂仅仅通过3小时的煎煮熬制而成。志愿者服用1个月后,对其补肾益气效果进行统计,结果如表1所示。
表1:
组别 | 人数 | 效果显著 | 效果一般 | 无效 | 有效率 |
实施例1 | 20人 | 18人 | 1人 | 1人 | 95% |
对照组1 | 20人 | 7人 | 9人 | 4人 | 80% |
实施例2 | 20人 | 19人 | 1人 | 0人 | 100% |
对照组2 | 20人 | 5人 | 12人 | 3人 | 85% |
实施例3 | 20人 | 17人 | 2人 | 1人 | 95% |
对照组3 | 20人 | 8人 | 7人 | 5人 | 75% |
由表1可以看出,服用实施例1-3制得的补肾益气养血安神滋补膏的志愿者,其亚健康状态的改善效果与采用相同份数比熬制成汤药的相应的对照组志愿者相比,有效率明显较高;同时,实施例1-3中志愿者的亚健康状态的改善效果中“效果显著”的占绝大部分,而对照组对志愿者亚健康状态改善效果中“效果一般”的占绝大部分。由此可见,本发明对人体的补肾益气效果显著。
Claims (4)
1.一种补肾益气养血安神滋补膏,其特征在于,原材料按照如下份数比组成:甘草8-12份、人参3-5份、枣仁4-7份、红枣6-10份、莲米2-5份、百合0.5-2份、龙眼肉7-10份、牡蛎3-5份、雪莲1-3份、山药1-3份、生姜2-3份、蜂蜜3-4份、黄秋葵4-6份、杜仲雄花1-4份、诺丽果3-5份、黑豆4-7份、蛹虫草3-5份、阿胶13-17份、蓝莓4-5份、枸杞子2-4份、地龙蛋白2-4份、沙棘2-3份。
2.如权利要求1所述的补肾益气养血安神滋补膏的制备工艺,其特征在于:制备方法如下:
(1)取甘草、人参、龙眼肉进行灭菌处理;
(2)将雪莲、百合、莲米、牡蛎用红外线烘烤,360W焙烤6min;
(3)将蛹虫草进行干燥处理,干燥后蛹虫草含水量为(5±1)%,干燥完成后粉碎过160目筛制成蛹虫草粉;
(4)将甘草、人参、龙眼肉、雪莲、百合、莲米、牡蛎与8倍质量的水进行加热煎煮,煎煮时间为2-3h,取上清液备用;
(5)将步骤(3)中的蛹虫草粉与步骤(4)中煎煮得到的上清液在69-75℃条件下搅拌,混合均匀,得到初配液;
(6)将步骤(5)中的初配液与处理干净的山药、生姜、黄秋葵、杜仲雄花、诺丽果、黑豆、蓝莓、枸杞子、沙棘以及9倍质量的水进行加热煎煮4-5h,浓缩成相对密度为2.6-2.8的粘稠液;
(7)将阿胶、地龙蛋白进行粉碎处理,过200目筛制成混合粉;
(8)将步骤(6)得到的粘稠液、步骤(7)中的阿胶、地龙蛋白混合粉以及蜂蜜混合,搅拌均匀成膏状。
3.如权利要求2所述的补肾益气养血安神滋补膏的制备工艺,其特征在于:所述步骤(3)蛹虫草进行干燥处理的温度为60-85℃。
4.如权利要求2所述的补肾益气养血安神滋补膏的制备工艺,其特征在于:所述步骤(4)中将加热煎煮温度为120-125℃。
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110679935A (zh) * | 2019-10-29 | 2020-01-14 | 天益食品(徐州)有限公司 | 一种牛蒡人参精华膏及其制备方法 |
CN110710678A (zh) * | 2019-11-20 | 2020-01-21 | 颐海产业控股有限公司 | 一种滋补肝肾、养血安神海洋多肽阿胶膏及其制备方法 |
CN112006192A (zh) * | 2020-08-18 | 2020-12-01 | 厦门真宴坊生物科技有限公司 | 一种人参饮品及其制备方法 |
CN114847480A (zh) * | 2022-05-11 | 2022-08-05 | 上海云梯医药科技有限公司 | 一种补肾壮阳组合物、制备方法及应用 |
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6372261B1 (en) * | 2000-07-07 | 2002-04-16 | Pharmaceutical Industry Technology And Development Center | Process for producing Guilu ErXiangao |
CN101537120A (zh) * | 2009-04-29 | 2009-09-23 | 田均 | 一种养颜益寿保健品 |
CN102846846A (zh) * | 2012-09-14 | 2013-01-02 | 山东福胶集团有限公司 | 一种阿胶膏及其制备方法 |
CN104856009A (zh) * | 2015-04-23 | 2015-08-26 | 贵州广济堂药业有限公司 | 一种杜仲雄花保健品 |
CN104856035A (zh) * | 2015-06-03 | 2015-08-26 | 贵州广济堂药业有限公司 | 调理特禀体质的保健品 |
CN105748824A (zh) * | 2016-04-01 | 2016-07-13 | 王琰 | 一种保元补血膏及其制作工艺 |
CN106901351A (zh) * | 2015-12-22 | 2017-06-30 | 焦秀英 | 益气补血膏 |
-
2017
- 2017-09-30 CN CN201710949548.4A patent/CN109601993A/zh active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6372261B1 (en) * | 2000-07-07 | 2002-04-16 | Pharmaceutical Industry Technology And Development Center | Process for producing Guilu ErXiangao |
CN101537120A (zh) * | 2009-04-29 | 2009-09-23 | 田均 | 一种养颜益寿保健品 |
CN102846846A (zh) * | 2012-09-14 | 2013-01-02 | 山东福胶集团有限公司 | 一种阿胶膏及其制备方法 |
CN104856009A (zh) * | 2015-04-23 | 2015-08-26 | 贵州广济堂药业有限公司 | 一种杜仲雄花保健品 |
CN104856035A (zh) * | 2015-06-03 | 2015-08-26 | 贵州广济堂药业有限公司 | 调理特禀体质的保健品 |
CN106901351A (zh) * | 2015-12-22 | 2017-06-30 | 焦秀英 | 益气补血膏 |
CN105748824A (zh) * | 2016-04-01 | 2016-07-13 | 王琰 | 一种保元补血膏及其制作工艺 |
Non-Patent Citations (2)
Title |
---|
光音等编: "《远红外加热干燥技术专辑》", 30 April 1979, 上海科学技术出版社 * |
蒋正国等: "《中华枸杞应用宝典》", 31 May 2016, 阳光出版社 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110679935A (zh) * | 2019-10-29 | 2020-01-14 | 天益食品(徐州)有限公司 | 一种牛蒡人参精华膏及其制备方法 |
CN110710678A (zh) * | 2019-11-20 | 2020-01-21 | 颐海产业控股有限公司 | 一种滋补肝肾、养血安神海洋多肽阿胶膏及其制备方法 |
CN112006192A (zh) * | 2020-08-18 | 2020-12-01 | 厦门真宴坊生物科技有限公司 | 一种人参饮品及其制备方法 |
CN114847480A (zh) * | 2022-05-11 | 2022-08-05 | 上海云梯医药科技有限公司 | 一种补肾壮阳组合物、制备方法及应用 |
CN116649516A (zh) * | 2023-06-21 | 2023-08-29 | 上海中药创新成果转化中心有限公司 | 一种补肾养血、抗衰老的植物饮料 |
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