CN109568528A - A kind of Chinese medicine composition that treating gastrointestinal disease and its application - Google Patents

A kind of Chinese medicine composition that treating gastrointestinal disease and its application Download PDF

Info

Publication number
CN109568528A
CN109568528A CN201910058420.8A CN201910058420A CN109568528A CN 109568528 A CN109568528 A CN 109568528A CN 201910058420 A CN201910058420 A CN 201910058420A CN 109568528 A CN109568528 A CN 109568528A
Authority
CN
China
Prior art keywords
parts
gastrointestinal disease
chinese medicine
medicine composition
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910058420.8A
Other languages
Chinese (zh)
Inventor
张书翔
王东艳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Pengye Shengshi Biotechnology Co Ltd
Original Assignee
Beijing Pengye Shengshi Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Pengye Shengshi Biotechnology Co Ltd filed Critical Beijing Pengye Shengshi Biotechnology Co Ltd
Priority to CN201910058420.8A priority Critical patent/CN109568528A/en
Publication of CN109568528A publication Critical patent/CN109568528A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Anesthesiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine composition for treating gastrointestinal disease and its applications, belong to technical field of traditional Chinese medicine preparation.The Chinese medicine composition of the treatment gastrointestinal disease, is made: 100-200 parts of cuttle bone, 10-20 parts of fructus alpiniae oxyphyllae, 50-100 parts of hawthorn, 30-60 parts of dalbergia wood, 40-80 parts of Chinese yam and 3-5 parts of medicinal fungus of the raw material of following parts by weight.The invention also discloses the applications of the Chinese medicine composition of above-mentioned treatment gastrointestinal disease.The Chinese medicine composition for the treatment of gastrointestinal disease of the invention, there is strengthening spleen, tonifying kidney, in tune the effect of clearing damp, clearing away heat and promoting diuresis, relieving QI stagnancy in the stomach analgesic, to various gastrointestinal diseases, such as the mental symptoms such as the several functions such as gastritis, gastric ulcer, duodenitis, duodenal ulcer gastrointestinal disease and adjoint insomnia, agitation, have a better effect.

Description

A kind of Chinese medicine composition that treating gastrointestinal disease and its application
Technical field
The present invention relates to a kind of Chinese medicine composition for treating gastrointestinal disease and its applications, belong to technical field of traditional Chinese medicine preparation.
Background technique
Gastrointestinal disease is the common disease of digestive system, frequently-occurring disease, and type is more, such as acute and chronic gastritis, enteritis, duodenum Ulcer etc..Stomach and intestine are the chief components of digestive system, are the major organs for digesting food, absorbing nutrition, once occur different Will often seriously affect the health of people, and gastrointestinal disease generally all has that the course of disease is long, it is slow, costly to respond well to treatment, more after The features such as easy to recur.Mostly use western medicine both at home and abroad at present, but western medicine is there are expenses for medicine height, side effect is big, treats the symptoms and does not control Originally, it is also easy to the defect of recurrence more afterwards, Chinese medicine then has the unconspicuous defect of curative effect mostly.
To sum up, need to develop a kind of Chinese medicine composition of new treatment gastrointestinal disease, to make up drawbacks described above.
Summary of the invention
An object of the present invention is to provide a kind of Chinese medicine composition for treating gastrointestinal disease.Treatment gastrointestinal disease of the invention Chinese medicine composition, there is strengthening spleen, tonifying kidney, in tune the effect of clearing damp, clearing away heat and promoting diuresis, relieving QI stagnancy in the stomach analgesic, to various gastrointestinal diseases, Such as the several functions such as gastritis, gastric ulcer, duodenitis, duodenal ulcer gastrointestinal disease and with insomnia, agitation Etc. mental symptoms, have a better effect.
The technical scheme to solve the above technical problems is that a kind of Chinese medicine composition for treating gastrointestinal disease, by such as The raw material of lower parts by weight is made: 100-200 parts of cuttle bone, 10-20 parts of fructus alpiniae oxyphyllae, 50-100 parts of hawthorn, 30-60 parts of dalbergia wood, 40-80 parts and medicinal fungus 3-5 parts of Chinese yam rhizome.
The raw material introduction that the present invention chooses:
Cuttle bone, be Sepiidae animal sepiella maindroni de Rochebrune or golden cuttlefish, prosperous cuttlefish, Sepia andreana, hickie cuttlefish, brave class cuttlefish, The inner casing of a variety of cuttlefishes such as quasi- mesh cuttlefish.Taste is salty, puckery, and slightly warm in nature returns liver and kidney channel, has astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving haperacidity to hold back Sore and other effects.
Fructus alpiniae oxyphyllae is the fruit of zingiberaceous plant intelligence development Alpinia oxyphyllaMiq..Saliva is taken the photograph with warming spleen and stopping diarrha, is warmed up The effect of kidney reducing urination controlling nocturnal emission with astringent drugs.Acrid flavour, warm-natured, returns spleen, kidney channel are usually used in deficiency-cold in spleen and stomach, vomiting, diarrhea, crymodynia, the more salivas of mouth in abdomen The illnesss such as saliva, enuresis with renal asthenia, frequent micturition, spermatorrhea, gonorrhoea.
Hawthorn also known as hawthorn, large-fruited Chinese hawthorn, rosaceae hawthorn, sweet in flavor, slightly warm in nature, acid enter spleen, stomach, Liver Channel, have and disappear The effect of eating stomach invigorating, activating microcirculation and removing stasis medicinal, expelling parasite, cures mainly meat stagnation, pediatric milk food stagnation, gastral cavilty abdominal pain, blood stasis closed, the postpartum stasis of blood The illnesss such as resistance, confidant sting, hernia pain, hyperlipemia.
Dalbergia wood, is used as medicine with the dry duramen of trunk and root, and acrid flavour is warm-natured, have promoting blood circulation to remove blood stasis, hemostasis analgesic therapy, sending down abnormally ascending, ward off it is dirty The effect of, cure mainly epigastric pain, liver depression costalgia, thoracic obstruction shouting pain, traumatic injury, traumatic hemorrhage and cold hernia pain or foul interior The illnesss such as the vomiting abdominal pain of resistance.
Chinese yam rhizome, sweet in flavor, mild-natured, returns spleen, lung, kidney channel, have tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission, it is clearing heat and detoxicating it Effect cures mainly the illnesss such as spleen eating less, endless diarrhea, the deficiency syndrome of the lung are breathed with cough, emission due to the kidney deficiency, leukorrhagia, frequent micturition, abnormal heat are quenched one's thirst.
Prescription solution:
Cuttle bone, taste is salty, puckery, and slightly warm in nature returns liver and kidney channel, has astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving haperacidity sore and other effects, is Monarch drug in a prescription.Chinese yam rhizome, hawthorn have food digesting stomach fortifying, activating microcirculation and removing stasis medicinal, expelling parasite, meat stagnation, the stagnation of cream food, gastral cavilty abdominal pain, hemostasis warp Close, postpartum stasis, confidant sting, hernia pain, tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission, it is clearing heat and detoxicating the effect of, be minister Medicine.Dalbergia wood has promoting blood circulation to remove blood stasis, hemostasis analgesic therapy, sending down abnormally ascending, wards off the effect of dirty, is adjutant.Fructus alpiniae oxyphyllae is taken the photograph saliva with warming spleen and stopping diarrha, is warmed up Kidney reducing urination controlling nocturnal emission with astringent drugs, deficiency-cold in spleen and stomach, vomiting, diarrhea, in abdomen the effect of crymodynia, to make medicine.The above bulk pharmaceutical chemicals synergistic effect, reaches jointly Into strengthening spleen, tonifying kidney, tune the effect of clearing damp, clearing away heat and promoting diuresis, relieving QI stagnancy in the stomach analgesic, to various gastrointestinal diseases, such as gastritis, gastric ulcer, The several functions such as duodenitis, duodenal ulcer gastrointestinal disease and with the mental symptoms such as insomnia, agitation, have compared with Good curative effect.
Method of administration: taking the Chinese materia medica preparation of above-mentioned treatment gastrointestinal disease, be added in thin rice gruel, takes orally.Three times a day, before meals With each 3.5g-7g.15 days as one therapeutic course, general two to three courses for the treatment of recovery from illness.Duration of medication avoids tobacco and wine, raw meat, cold, peppery, oily Greasy food, the good work and rest habit of holding, learns rationally decompression, actively participates in outdoor sports, pay attention to keeping warm, loosen mood, to the greatest extent Amount avoids staying up late.
Based on the above technical solution, the present invention can also be improved as follows.
Further, it is made of the raw material of following parts by weight: 100 parts of cuttle bone, 20 parts of fructus alpiniae oxyphyllae, 60 parts of hawthorn, dalbergia wood 50 parts, 70 parts of Chinese yam rhizome, 3.5 parts of medicinal fungus.
Further, it is made of the raw material of following parts by weight: 150 parts of cuttle bone, 15 parts of fructus alpiniae oxyphyllae, 75 parts of hawthorn, dalbergia wood 40 parts, 50 parts of Chinese yam rhizome and 4 parts of medicinal fungus.
Further, it is made of the raw material of following parts by weight: 200 parts of cuttle bone, 10 parts of fructus alpiniae oxyphyllae, 100 parts of hawthorn, dalbergia wood 40 parts, 60 parts of Chinese yam rhizome and 5 parts of medicinal fungus.
Further, the cuttle bone, the fructus alpiniae oxyphyllae, the hawthorn, the dalbergia wood and the Chinese yam rhizome are to be added After medicinal fungus fermentation, it is crushed to obtained by 200 mesh.
The second object of the present invention is to provide the application of the Chinese medicine composition of above-mentioned treatment gastrointestinal disease.Above-mentioned treatment stomach and intestine The Chinese medicine composition of disease can be used to prepare the drug for the treatment of gastrointestinal disease individually or as active component.
The technical scheme to solve the above technical problems is that the Chinese medicine composition of above-mentioned treatment gastrointestinal disease is independent Or the application in the drug for treating gastrointestinal disease is prepared as active component.
The third object of the present invention is to provide a kind of Chinese materia medica preparation for treating gastrointestinal disease.The Chinese medicine of above-mentioned treatment gastrointestinal disease One or more pharmaceutically acceptable auxiliary materials can be added in composition, be used to prepare the medicine of the treatment gastrointestinal disease of various dosage forms Object.
The technical scheme to solve the above technical problems is that a kind of Chinese materia medica preparation for treating gastrointestinal disease, takes above-mentioned Treatment gastrointestinal disease Chinese medicine composition, be added starch, oligofructose, sodium carboxymethyl starch, microcrystalline cellulose, in potassium sorbate One or more pharmaceutically acceptable auxiliary materials, routinely technique be made pill, sublimed preparation, electuary, oral solutions, capsule, Powder, paste, granule or tablet.
The fourth object of the present invention is to provide the preparation method of the Chinese materia medica preparation of above-mentioned treatment gastrointestinal disease.Of the invention controls The preparation method for treating the Chinese materia medica preparation of gastrointestinal disease is simple, low in cost, and Chinese medicine is after hot fermentation, can generate beneficial bacterium, Multichain enzyme, enteron aisle are easier to absorb, and the drug effect of Chinese medicine can increase 5 times or more, and wide market is suitble to large-scale production.
The technical scheme to solve the above technical problems is that a kind of preparation side for the Chinese materia medica preparation for treating gastrointestinal disease Method includes the following steps:
Take the raw material of following parts by weight: 100-200 parts of cuttle bone, 10-20 parts of fructus alpiniae oxyphyllae, 50-100 parts of hawthorn, dalbergia wood 30-60 parts and Chinese yam rhizome 40-80 part, clean up, and are added medicinal fungus 3-5 part, ferment, dry, pulverize, addition starch, oligomeric One of fructose, sodium carboxymethyl starch, microcrystalline cellulose, potassium sorbate or a variety of pharmaceutically acceptable auxiliary materials, routinely Pill, sublimed preparation, electuary, oral solutions, capsule, powder, paste, granule or tablet is made to get the treatment stomach in technique The Chinese materia medica preparation of enteropathy.
Based on the above technical solution, the present invention can also be improved as follows.
Further, the medicinal fungus is golden cicada pollen;The temperature of the fermentation is 28 DEG C -35 DEG C, and the time of fermentation is 12h-24h;The temperature of the drying is 50 DEG C -60 DEG C, and the dry time is 8h-12h;The partial size of the crushing is 200 mesh.
Beneficial effects of the present invention:
(1) Chinese medicine composition for the treatment of gastrointestinal disease of the invention, with clearing damp, clearing away heat and promoting diuresis, promoting the circulation of qi in strengthening spleen, tonifying kidney, tune The effect of protecting the stomach and relieve the pain, to multiple functions such as various gastrointestinal diseases, such as gastritis, gastric ulcer, duodenitis, duodenal ulcer Property gastrointestinal disease and with the mental symptoms such as insomnia, agitation, have a better effect.
(2) Chinese medicine composition for the treatment of gastrointestinal disease of the invention is applied widely, treating both manifestation and root cause of disease, quick, curative effect is stable, Non-relapse after healing has no toxic side effect.
(3) Chinese medicine composition for the treatment of gastrointestinal disease of the invention can be used to prepare treatment individually or as active component The drug of gastrointestinal disease.
(4) Chinese medicine composition for the treatment of gastrointestinal disease of the invention can be added one or more pharmaceutically acceptable auxiliary Material, is used to prepare the drug of the treatment gastrointestinal disease of various dosage forms.
(5) preparation method of the Chinese materia medica preparation for the treatment of gastrointestinal disease of the invention is simple, low in cost, and Chinese medicine passes through high temperature After fermentation, beneficial bacterium, multichain enzyme can be generated, enteron aisle is easier to absorb, and the drug effect of Chinese medicine can increase 5 times or more, and market prospects are wide It is wealthy, it is suitble to large-scale production.
Specific embodiment
Principles and features of the present invention are described below in conjunction with specific embodiment, example is served only for explaining this hair It is bright, it is not intended to limit the scope of the present invention.
Embodiment 1
The Chinese medicine composition of the treatment gastrointestinal disease of the present embodiment, is made of the raw material of following weight: cuttle bone 100kg, benefit Intelligence benevolence 20kg, hawthorn 60kg, dalbergia wood 50kg, Chinese yam rhizome 70kg and golden cicada pollen 3.5kg.
Application of the Chinese medicine composition of above-mentioned treatment gastrointestinal disease in the drug that treatment gastrointestinal disease is prepared separately.
The Chinese materia medica preparation of the treatment gastrointestinal disease of the present embodiment, takes Chinese medicine composition as described above, routinely technique is made Pill.
The preparation method of the Chinese materia medica preparation of above-mentioned treatment gastrointestinal disease, includes the following steps:
Take the raw material of following weight: cuttle bone 100kg, fructus alpiniae oxyphyllae 20kg, hawthorn 60kg, dalbergia wood 50kg and Chinese yam rhizome 70kg It cleans up, golden cicada pollen 3.5kg is added, the temperature of fermentation is 30 DEG C, time 20h, and dry temperature is 50 DEG C, and the time is 12h is crushed to 200 mesh, and starch 100kg, oligofructose 60kg and potassium sorbate 1.5kg is added, and routinely pill is made in technique, Every 0.3g is to get the Chinese materia medica preparation for treating gastrointestinal disease.
Embodiment 2
The Chinese medicine composition of the treatment gastrointestinal disease of the present embodiment, is made of the raw material of following weight: cuttle bone 150kg, benefit Intelligence benevolence 15kg, hawthorn 75kg, dalbergia wood 40kg, Chinese yam rhizome 50kg and golden cicada pollen 4kg.
Application of the Chinese medicine composition of above-mentioned treatment gastrointestinal disease in the drug for preparing treatment gastrointestinal disease as active component.
The Chinese materia medica preparation of the treatment gastrointestinal disease of the present embodiment takes Chinese medicine composition as described above, and it is fine that starch, crystallite is added Dimension element and potassium sorbate, routinely electuary is made in technique.
The preparation method of the Chinese materia medica preparation of above-mentioned treatment gastrointestinal disease, includes the following steps:
Take the raw material of following weight: cuttle bone 150kg, fructus alpiniae oxyphyllae 15kg, hawthorn 75kg, dalbergia wood 40kg and Chinese yam rhizome 50kg is cleaned up, and golden cicada pollen 4kg is added, and the temperature of heating fermentation is 32 DEG C, time 15h, and drying temperature is 60 DEG C, Time is 8h, is crushed to 200 mesh, oligofructose 90kg, microcrystalline cellulose 120kg and potassium sorbate 2kg is added, routinely technique Electuary is made, packs, every bag of 3.5g.Up to the Chinese materia medica preparation of the treatment gastrointestinal disease.
Embodiment 3
The Chinese medicine composition of the treatment gastrointestinal disease of the present embodiment, is made of the raw material of following weight: cuttle bone 200kg, benefit Intelligence benevolence 10kg, hawthorn 100kg, dalbergia wood 40kg, Chinese yam rhizome 60kg and golden cicada pollen 5kg.
Application of the Chinese medicine composition of above-mentioned treatment gastrointestinal disease in the drug for preparing treatment gastrointestinal disease as active component.
The Chinese materia medica preparation of the treatment gastrointestinal disease of the present embodiment takes Chinese medicine composition as described above, and oligofructose is added 100kg, sodium carboxymethyl starch 150kg and potassium sorbate 3kg, routinely granule is made in technique.
The preparation method of the Chinese materia medica preparation of above-mentioned treatment gastrointestinal disease, includes the following steps:
Take the raw material of following weight: cuttle bone 200kg, fructus alpiniae oxyphyllae 10kg, hawthorn 100kg, dalbergia wood 40kg and Chinese yam rhizome 60kg is cleaned up, and golden cicada pollen 5kg is added, and the temperature of fermentation is 30 DEG C, time 18h, and dry temperature is 55 DEG C, when Between be 10h, be crushed to 200 mesh, oligofructose 100kg, sodium carboxymethyl starch 150kg and potassium sorbate 3kg be added, routinely work Granule is made in skill, pack, every bag of 4g.Up to the Chinese materia medica preparation of the treatment gastrointestinal disease.
Clinical example
Present inventor carries out clinical observation to 166 stomach and intestine patients and controls in July, 2014 in October, 2017 It treats, the age -75 years old 25 years old, differs within the course of disease -15 years 1 year.
<diagnostic criteria>: judged with clinical symptoms.Wherein, gastritis: indigestion, loss of appetite, gasteremphraxis, stomachache, belch Sour regurgitation, bitter taste is tasteless, lean and haggard etc..
Gastric ulcer: in addition to gastritis symptom, clinical manifestation is the frequent pain of stomach, even severe pain, nausea and vomiting, Stool often with black, occasionally there is haematemesis etc..
Duodenitis: indigestion, the frequent pain of stomach lower abdomen, when with diarrhea etc..
Duodenal ulcer: clinical manifestation is that the pain increased, frequent diarrhea, often band black etc. of defecating.
In short, gastrointestinal disease is mostly chronic disease, from the pathology course of disease, causes a disease because improper diet, often opened with mucosa irritation Begin, is gradually developed to mucosal erosion, bleeding, or even perforation.From symptom, using indigestion and pain as main feature;Sternly Severe one is such as spitted blood, hematochezia symptom, or even causes anaemia, syntexis etc. with bleeding.
<treatment method>: the Chinese materia medica preparation for the treatment gastrointestinal disease that Example 2 obtains is added in thin rice gruel, is taken orally.Daily Three times, bfore meals, each 3.5g-7g.15 days as one therapeutic course.
<efficacy assessment standard>:
" healing ": Rehabilitation.
" effective ": patient symptom is substantially reduced.
Engineering noise: after taking 1 course for the treatment of, patient symptom has no to change or change unobvious.
<therapeutic effect>:
Clinical cure 166, account for 100%, wherein gastritis 77, gastric ulcer 23, duodenitis 45,12 refer to Enterelcosis 21.
Typical clinical example 1
Mr. Lin, male, 49 years old, Guiyang Qingzhen City forensic work.First visit in March, 2012.Private prosecution is with stomachache, gasteremphraxis, oh More than ten years, exacerbation in nearly 2 months have been unable to normal diet, daily using congee as staple food, have done through Kweiyang the People's Hospital inverse, gastric acid Gastrocopy: stomach hook, intestinal metaplasia, stomach lining oedema are diagnosed as chronic superficial gastritis.March 11 took the embodiment of the present invention The Chinese materia medica preparation of 2 obtained treatment gastrointestinal diseases, is added in thin rice gruel, takes orally.Three times a day, bfore meals, 1 bag every time.15 days It is as a treatment course.
26 days two March in 2012 examines.Private prosecution stomachache, gasteremphraxis, heating are obviously taken a favourable turn, can be normal after medication 10 days Diet.Medicine is taken to take again 15 days.
10 days three April in 2012 examines.Private prosecution stomachache, gasteremphraxis, the symptom of gastric acid have substantially eliminated, and appetite is good, have rosy cheeks, Weight gain 2kg, it is contemplated that patient has more than ten years, then takes 15 days and consolidate effect.Follow-up 2 years, no relapse.
Typical clinical example 2
Qiao Jian, male, 35 years old, people from Hunan, crane maintenance work.The first visit of in September, 2013.Private prosecution stomachache, gasteremphraxis, gastric acid are More than 2 years, because working principle diet is irregular, various stomach medicines were eaten, again and again.It aggravates within the next few days, the gasteremphraxis that has a stomach-ache is severe, often It is food with gruel, and through In Qiannan, gastrocopy is done by institute of traditional Chinese medicine: being diagnosed as atrophic gastritis, erosive gastritis.It takes within September 20 days The Chinese materia medica preparation for the treatment gastrointestinal disease that the embodiment of the present invention 3 obtains, 3 times a day, 1 bag every time.15 days as one therapeutic course.
6 days two October in 2013 examines.Private prosecution stomachache, gasteremphraxis are obviously taken a favourable turn, can normal diet after medication 7 days.Again Medicine is taken to take 15 days.
21 days three October in 2013 examines.Private prosecution stomachache, gasteremphraxis symptom substantially eliminated, appetite is especially good, has rosy cheeks. Follow-up 2 years, no relapse.
Typical clinical example 3
Mr. Wang, female, 61 years old, retired professor.First visit in May, 2015.Private prosecution was had a stomachache before 3 years without obvious inducement, warp Often breaking-out, cut-like pain, then pain more very, checks there is chronic gastritis, gastric ulcer through certain hospital to food, with Western medicine symptomatic treatment, When light when the state of an illness again, it seeks medical advice then.It is existing symptoms include: body is partially thin, lustreless complexion, spiritlessness and sparing of words, gastral cavilty cut-like pain, then aches after food Pain is more very, dizzy with acid regurgitation, limb cold, nearly 3 days stool black.That took that the embodiment of the present invention 2 obtains on May 20 controls Treat the Chinese materia medica preparation of gastrointestinal disease, 3 times a day, 2 bags every time.15 days as one therapeutic course.
6 days two June in 2015 examines.Private prosecution stomachache mitigates, and melena has stopped.Due to have a stomachache with the passing of time, transporting it is powerless.Gastric acid is bright Obvious light, after medication 10 days, diet improves than original.Medicine is taken to take again 15 days.
21 days three June in 2015 examines.Private prosecution stomachache, gastric acid symptom substantially eliminated, appetite is normal, glowing with health, suffers from Person is very satisfied.Follow-up 2 years, no relapse.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (9)

1. a kind of Chinese medicine composition for treating gastrointestinal disease, which is characterized in that be made of the raw material of following parts by weight: cuttle bone 100-200 parts, 10-20 parts of fructus alpiniae oxyphyllae, 50-100 parts of hawthorn, 30-60 parts of dalbergia wood, 40-80 parts of Chinese yam rhizome and 3-5 parts of medicinal fungus.
2. the Chinese medicine composition for the treatment of gastrointestinal disease according to claim 1, which is characterized in that by the original of following parts by weight Material is made: 100 parts of cuttle bone, 20 parts of fructus alpiniae oxyphyllae, 60 parts of hawthorn, 50 parts of dalbergia wood, 70 parts of Chinese yam rhizome and 3.5 parts of medicinal fungus.
3. the Chinese medicine composition for the treatment of gastrointestinal disease according to claim 1, which is characterized in that by the original of following parts by weight Material is made: 150 parts of cuttle bone, 15 parts of fructus alpiniae oxyphyllae, 75 parts of hawthorn, 50 parts of dalbergia wood, 50 parts of Chinese yam rhizome and 4 parts of medicinal fungus.
4. the Chinese medicine composition for the treatment of gastrointestinal disease according to claim 1, which is characterized in that by the original of following parts by weight Material is made: 200 parts of cuttle bone, 10 parts of fructus alpiniae oxyphyllae, 100 parts of hawthorn, 40 parts of dalbergia wood, 60 parts of Chinese yam rhizome and 5 parts of medicinal fungus.
5. the Chinese medicine composition for the treatment of gastrointestinal disease according to claim 1-4, which is characterized in that the cuttlefish After bone, the fructus alpiniae oxyphyllae, the hawthorn, the dalbergia wood and the Chinese yam rhizome are heating fermentation, it is crushed to obtained by 200 mesh.
6. a kind of Chinese medicine composition for the treatment of gastrointestinal disease according to any one of claims 1-4 is individually or as active component Application in the drug of preparation treatment gastrointestinal disease.
7. a kind of Chinese materia medica preparation for treating gastrointestinal disease, which is characterized in that take the described in any item treatment gastrointestinal diseases of claim 1-4 Chinese medicine composition, starch, oligofructose, sodium carboxymethyl starch, microcrystalline cellulose, one of potassium sorbate or a variety of is added Pharmaceutically acceptable auxiliary material, routinely technique be made pill, sublimed preparation, electuary, oral solutions, capsule, powder, paste, Granula or tablet.
8. a kind of preparation method for the Chinese materia medica preparation for treating gastrointestinal disease, which comprises the steps of:
Take the raw material of following parts by weight: 100-200 parts of cuttle bone, 10-20 parts of fructus alpiniae oxyphyllae, 50-100 parts of hawthorn, dalbergia wood 30-60 Part and Chinese yam rhizome 40-80 part, clean up, be added medicinal fungus 3-5 part, ferment, dry, pulverize, addition starch, oligofructose, One of sodium carboxymethyl starch, microcrystalline cellulose, potassium sorbate or a variety of pharmaceutically acceptable auxiliary materials, routinely technique system At pill, sublimed preparation, electuary, oral solutions, capsule, powder, paste, granule or tablet to get the treatment gastrointestinal disease Chinese materia medica preparation.
9. the preparation method of the Chinese materia medica preparation for the treatment of gastrointestinal disease according to claim 8, which is characterized in that the medicinal fungus For golden cicada pollen;The temperature of the fermentation is 28 DEG C -35 DEG C, and the time of fermentation is 12h-24h;The temperature of the drying is 50 DEG C -60 DEG C, the dry time is 8h-12h;The partial size of the crushing is 200 mesh.
CN201910058420.8A 2019-01-22 2019-01-22 A kind of Chinese medicine composition that treating gastrointestinal disease and its application Pending CN109568528A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910058420.8A CN109568528A (en) 2019-01-22 2019-01-22 A kind of Chinese medicine composition that treating gastrointestinal disease and its application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910058420.8A CN109568528A (en) 2019-01-22 2019-01-22 A kind of Chinese medicine composition that treating gastrointestinal disease and its application

Publications (1)

Publication Number Publication Date
CN109568528A true CN109568528A (en) 2019-04-05

Family

ID=65917635

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910058420.8A Pending CN109568528A (en) 2019-01-22 2019-01-22 A kind of Chinese medicine composition that treating gastrointestinal disease and its application

Country Status (1)

Country Link
CN (1) CN109568528A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1413681A (en) * 2002-11-05 2003-04-30 常健 Medicine for treating stomach trouble
CN1528446A (en) * 2003-10-20 2004-09-15 青先伦 Oral medicine for treating gastro intestinal diseases and preparing method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1413681A (en) * 2002-11-05 2003-04-30 常健 Medicine for treating stomach trouble
CN1528446A (en) * 2003-10-20 2004-09-15 青先伦 Oral medicine for treating gastro intestinal diseases and preparing method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
郝丽艳 等: "慢性胃炎诊治心得", 《长春中医药大学学报》 *

Similar Documents

Publication Publication Date Title
CN101791388B (en) Traditional Chinese medicine preparation for treating peptic ulcer
CN105663750A (en) Traditional Chinese medicinal composition for treating stomachache and preparation method of traditional Chinese medicinal composition
CN105169212A (en) Traditional Chinese medicine composition for treating chronic gastritis
CN101721667A (en) Traditional Chinese medicine for treating indigestion
CN105796712B (en) Traditional Chinese medicine composition for treatment of superficial gastritis
CN109771602A (en) For treating external application type Traditional Chinese medicine composition patch, preparation and its application of diarrhea
CN103055111B (en) Traditional Chinese medicine composition for treating children&#39;s infantile malnutrition and preparation method thereof
CN104667188A (en) Traditional Chinese medicine preparation for treating sphagitis
CN109568528A (en) A kind of Chinese medicine composition that treating gastrointestinal disease and its application
CN105998551A (en) Traditional Chinese medicine composition for treating stomachache and preparation method thereof
CN105168522A (en) Medicament for treating abdominal distension and preparation method thereof
CN107854662A (en) A kind of Chinese medicine preparation for treating cirrhotic ascites and preparation method thereof
CN103520652A (en) Traditional Chinese medicine composition for treating liver cancer
CN103100049A (en) Traditional Chinese medicine preparation for treating gall-stone and cholecystitis, and preparation method thereof
CN107582831A (en) It is a kind of effectively to alleviate gaseous distention and the Chinese medicine composition of hiccup
CN114053378A (en) Ginseng and coptis chinensis stomach-clearing traditional Chinese medicine composition as well as preparation method and application thereof
CN103751240B (en) A kind of pharmaceutical composition for the treatment of gastritis and enteritis
CN107596261A (en) A kind of Chinese medicine composition for treating taste-blindness rate and preparation method thereof
CN107551043A (en) A kind of endo-medicine for treating children&#39;s exogenous fever and preparation method thereof
CN107468805A (en) A kind of endo-medicine for treating children&#39;s exogenous fever and preparation method thereof
CN101095876A (en) Chinese medicine preparation for treating diabetes respiratory tract infection
CN107184925A (en) Treat the Chinese medicine composition of chronic pharyngitis
CN108704062A (en) A kind of Chinese medicine composition and preparation method thereof for treating coronary heart disease
CN108042725A (en) A kind of Chinese medicine preparation for treating stone in urinary system and preparation method thereof
CN1425453A (en) Medicine for curing diseases of gastrointestinal system

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190405