CN1413681A - Medicine for treating stomach trouble - Google Patents

Medicine for treating stomach trouble Download PDF

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Publication number
CN1413681A
CN1413681A CN 02134010 CN02134010A CN1413681A CN 1413681 A CN1413681 A CN 1413681A CN 02134010 CN02134010 CN 02134010 CN 02134010 A CN02134010 A CN 02134010A CN 1413681 A CN1413681 A CN 1413681A
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China
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finished product
fructus
medicine
extractum
semi
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CN 02134010
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Chinese (zh)
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CN100333781C (en
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常健
赵品莉
常昊
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Individual
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Publication of CN1413681A publication Critical patent/CN1413681A/en
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Abstract

A Chinese medicine in the form of capsule, instant particle, or liquid for treating enterogastropathy, such as gastritis, gastric ulcer, enterogastric function disorder, enteritis, etc. is prepared from 7 Chinese-medicinal materials including yam, radish seed, amomum fruit, tangerine peel, etc. It has high curative effect.

Description

The medicine of treatment gastroenteropathy
Technical field:
The present invention is relevant with the Chinese medicine medicine of treatment nerve gastroenteropathy, enteritis, gastritis, gastric ulcer, gastrointestinal dysfunction disorder.
Technical background:
The Chinese medicine medicine of existing treatment nerve gastroenteropathy, gastritis, gastric ulcer, gastrointestinal dysfunction disorder, function is more single, and curative effect is remarkable inadequately, and takes and store inconvenience.
Summary of the invention:
It is simple to the purpose of this invention is to provide a kind of prescription, is convenient to store and take the medicine of the treatment gastroenteropathy that reciprocity multiple gastroenteropathy is powerful.
The present invention is achieved in that
The present invention is the medicine of treatment gastroenteropathy, and the weight ratio of its raw material is as follows:
Rhizoma Dioscoreae 15-45
Semen Raphani 20-50
Fructus Alpiniae Oxyphyllae 15-25
Fructus Amomi 15-30
Pericarpium Citri Reticulatae 10-35
Fructus Crataegi 15-30
Seem Lablab Album 10-35
Rhizoma Dioscoreae, Semen Raphani, Fructus Amomi, Seem Lablab Album, Fructus Alpiniae Oxyphyllae, Fructus Crataegi are processed into fine powder, Pericarpium Citri Reticulatae are soaked produce supernatant, fine powder, supernatant are mixed, add the ethanol lixiviate, make the extractum semi-finished product and make capsule or tablet or electuary or water preparation again.
Raw material fine powder of the present invention is the 80-200 order, mixes the back with supernatant that Pericarpium Citri Reticulatae is produced and adds with 1: 2 proportion and contain 80% alcoholic solution lixiviate, and refine is condensed into the extractum semi-finished product.
The present invention makes extractum semi-finished product tabletting tablet or the dry powder process of extractum semi-finished product is packed into electuary.
The present invention adds distilled water after with the powder process of extractum semi-finished product and makes water preparation.
The present invention with extractum semi-finished product vacuum drying after powder process, add adjuvant and make capsule.
The present invention is principal agent (monarch drug) with the Rhizoma Dioscoreae, and Rhizoma Dioscoreae contains the active active substance of flavonoid, and necessary trace element and the several amino acids of human body such as ferrum, zinc, calcium, magnesium have the effect of the multiple gastroenteropathy of treatment.With Semen Raphani, Fructus Crataegi, Pericarpium Citri Reticulatae and Semen Lablab Album is ministerial drug.Semen Raphani contains significant quantities of fat oil, and polysaccharide flavonoid glycoside etc. can be treated retention of food and drink, abdominal distention, stomachache; Fructus Crataegi contains multiple flavone and organic acid, have help digestion, the effect of intestinal stasis relieving, circulation of qi promoting dissipating blood stasis; Pericarpium Citri Reticulatae contains the multiple aminoacid useful to stomach, can spleen reinforcing be good for the stomach.Seem Lablab Album contains rich in protein, carotene, vitamin B complex, can wet by strengthening the spleen and stomach.We are adjuvant drug with the Pericarpium Citri Reticulatae that the Fructus Alpiniae Oxyphyllae and the energy circulation of qi promoting of energy " strengthening the spleen stomach, reason vigour " are good for the stomach also.Because Fructus Amomi has the effect of " drawing public region, all medicines home to return to ", " with closing the five internal organs towards the gas that closes ", is messenger drug so we are equipped with Fructus Amomi.By cooperatively interacting of " monarch, minister, help, make " various kinds of drug, this has just improved the synergism of formulation of drug, has transferred efficiency of drugs, has strengthened the effect of this prescription protection the intestines and stomach, treatment gastroenteropathy.
By the detection certificate of analysis, the active effective ingredient 〉=26.0mg/100g of flavonoid of the present invention, amino acid content 〉=7000.0mg/100g, they are effective ingredient of treatment and protection the intestines and stomach.
Contain important biomolecule reactive compounds such as adjusting gastrointestinal function, antitumor in the flavone compound.
Aminoacid supplements the nutrients for each routine patients with gastric disease, supports that the stomach functional rehabilitation is significant.In the gastrotherapy process, must strengthen the reparation of gastrointestinal function damage on one side, will cooperate supporting treatment on one side, wherein aminoacid is to safeguarding patient's nutritional status, it is significant to improve the stomach function.
Protein contents such as the Seem Lablab Album among the present invention, Pericarpium Citri Reticulatae, Fructus Alpiniae Oxyphyllae, Fructus Amomi are all abundanter, and the gastrointestinal function impairer is supplemented the nutrients, and support the stomach functional rehabilitation to have certain meaning.The functional experiment that carries out in West China medical university shows that the present invention has remarkable efficacy to gastritis, gastric ulcer, gastric mucosa abscission, gastrointestinal dysfunction disorder, enteritis, nerve gastroenteropathy, inappetence, dyspepsia, flatulence, stomachache etc.
We have carried out clinical experiment to various gastroenteropathy patients, formulated clinical prerun scheme according to " the gastroenteropathy clinical research guideline of new Chinese medicine treatment ", close each 4 these capsules of gastritis sufferer of symbol condition, 3 times on the one, show that by 100 routine gastritis sufferers being treated observe the medication effect of preparing by this prescription is good.75 examples of wherein recovering, remarkable 14 examples, effective 9 examples, total obvious effective rate 89%, total effective rate 98%.
Equally, flatulence, stomachache person 80 people are carried out clinical prerun, give qualified patient each 5 these capsules, 3 times on the one, 70 examples of wherein recovering, produce effects 5 examples, effective 4 examples, total obvious effective rate 93.75%, total effective rate 98.7%.
Medicine gastric mucosa abscission patient 60 people are carried out clinical prerun, give qualified patient each 4 these capsules, 3 times on the one, 48 examples of wherein recovering, produce effects 8 examples, effective 3 examples, total obvious effective rate 97.3%, total effective rate 98.3%.
Nerve gastroenteropathy patient 120 people are carried out clinical prerun, give qualified patient each 5 these capsules, 3 times on the one, 105 examples of wherein recovering, produce effects 10 examples, effective 3 examples, total obvious effective rate 95.8%, total effective rate 98.3%.
Enteritis patient 60 people are carried out clinical prerun, give qualified patient each 4 these capsules, 3 times on the one, 46 examples of wherein recovering, produce effects 10 examples, effective 3 examples, total obvious effective rate 93.3%, total effective rate 98.3%.
This medicine is to patient's curative effect unanimity of all ages and classes, the different courses of disease, and is respond well, specializes, and curative effect is determined, do not found obvious adverse reaction in the experiment.
In sum as can be known, the present invention has remarkable efficacy to gastritis, gastric ulcer, gastric mucosa abscission, gastrointestinal dysfunction disorder, enteritis, nerve gastroenteropathy and by the caused inappetence of above disease, dyspepsia, flatulence, stomachache etc.
The specific embodiment:
Fill a prescription as following table:
????1 ????2 ????3 ????4 ????5
Rhizoma Dioscoreae ????15 ????45 ????30 ????35 ????40
Semen Raphani ????20 ????30 ????40 ????50 ????25
Fructus Alpiniae Oxyphyllae ????25 ????5 ????15 ????10 ????18
Fructus Amomi ????15 ????30 ????20 ????18 ????25
Pericarpium Citri Reticulatae ????35 ????10 ????20 ????15 ????25
Fructus Crataegi ????15 ????30 ????20 ????25 ????18
Seem Lablab Album ????10 ????35 ????25 ????20 ????15
Preparation technology:
To remove the peel Fructus Amomi, Semen Raphani, Fructus Alpiniae Oxyphyllae, Seem Lablab Album, Fructus Crataegi selected, clean, filter, the oven dry post-treatment is 80-200 order fine powder.
Rhizoma Dioscoreae is cleaned, is broken for 1cm * 1cm fragment behind the thin slice, drying, and crude fibre is removed in processing, sifts out 80-200 order fine powder.
Pericarpium Citri Reticulatae is selected, clean, filter, add water purification 3 times, concentrate, filtering residue, taking-up supernatant mix with said components raw material fine powder, contains 80% alcoholic solution with proportion adding in 1: 2.Homogenizing, stirred evenly, leave standstill 15 hours.
Deployed liquid is transported between the clean area vehicle of sterilization puts it in the concentrator, temper being bordering under 95 ℃ of the boiling points, concentrate, add an amount of demineralized water, constantly stir, allow it fully dissolve mixing, when forming the solid paste gradually, take out mastic and put into stainless steel disc and leave standstill 15 minutes (add film-making agent then can with the mastic direct compression).
With the mastic chopping, send in the Minton dryer, carry out dry concentration.Because raw material contains multiple bioactive ingredients and volatilization wet goods, can only under 90 ℃ condition, toast 3.5 hours, when moisture during in 9% left and right sides, take out stainless steel disc, take rapidly into full closed aseptic workshop (dry back powder process packs into the electuary product, adding distil water, sterilization, bottle into aqua product).
To dry after granule makes powder in sterile workshop, enter another full closed aseptic chamber,, go into capsule with automatic capsule machine powder filler with one of percentage Libra weighing metering.

Claims (5)

1, the medicine of treatment gastroenteropathy is characterized in that the weight ratio of its raw material is as follows:
Rhizoma Dioscoreae 15-45
Semen Raphani 20-50
Fructus Alpiniae Oxyphyllae 15-25
Fructus Amomi 15-30
Pericarpium Citri Reticulatae 10-35
Fructus Crataegi 15-30
Seem Lablab Album 10-35
Rhizoma Dioscoreae, Semen Raphani, Fructus Amomi, Seem Lablab Album, Fructus Alpiniae Oxyphyllae, Fructus Crataegi are processed into fine powder, Pericarpium Citri Reticulatae are soaked produce supernatant, fine powder, supernatant are mixed, add the ethanol lixiviate, make the extractum semi-finished product and make capsule or tablet or electuary or water preparation again.
2, medicine according to claim 1 is characterized in that the raw material fine powder is the 80-200 order, mixes the back with supernatant that Pericarpium Citri Reticulatae is produced and adds with 1: 2 proportion and contain 80% alcoholic solution lixiviate, and refine is condensed into the extractum semi-finished product.
3, medicine according to claim 1 is characterized in that extractum semi-finished product tabletting is made tablet or the dry powder process of extractum semi-finished product is packed into electuary.
4, medicine according to claim 3 is characterized in that making water preparation with adding distilled water after the powder process of extractum semi-finished product.
5, medicine according to claim 3 is characterized in that powder process behind the extractum semi-finished product vacuum drying, adds adjuvant and makes capsule.
CNB021340102A 2002-11-05 2002-11-05 Medicine for treating stomach trouble Expired - Fee Related CN100333781C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB021340102A CN100333781C (en) 2002-11-05 2002-11-05 Medicine for treating stomach trouble

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Application Number Priority Date Filing Date Title
CNB021340102A CN100333781C (en) 2002-11-05 2002-11-05 Medicine for treating stomach trouble

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CN100333781C CN100333781C (en) 2007-08-29

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103005264A (en) * 2012-12-28 2013-04-03 深圳市深博泰生物科技有限公司 Chitosan oligosaccharide-containing healthcare food and preparation method thereof
CN103416671A (en) * 2013-08-05 2013-12-04 赵杏珍 Medicinal and edible noodle capable of regulating stomach and intestine
CN104140905A (en) * 2013-05-11 2014-11-12 陈洪波 Digestion helping and stomach strengthening beer
CN104623478A (en) * 2015-01-23 2015-05-20 广州中医药大学 Medicine for regulating spleen-deficiency syndrome type intestinal bacilli illness and preparation method thereof
CN105012672A (en) * 2015-07-29 2015-11-04 青岛蓝盛洋医药生物科技有限责任公司 Traditional Chinese medicine composition for treating gastrointestinal dysfunction and preparation method of traditional Chinese medicine composition
CN106344863A (en) * 2016-08-30 2017-01-25 广州领康科技有限公司 Fructus amomi and hericium erinaceus tablet candy for targeted repairing of stomach
CN107661434A (en) * 2017-08-17 2018-02-06 福建省招宝生态农庄有限公司 A kind of medicine for eliminating pig abdominal distension grave illness and application
CN109287921A (en) * 2018-09-29 2019-02-01 首益特殊医学用途配方食品科技研究(北京)有限公司 Diet therapy nutritional element solid beverage and preparation method thereof for inflammatory bowel disease
CN109568528A (en) * 2019-01-22 2019-04-05 北京朋烨盛世生物科技有限公司 A kind of Chinese medicine composition that treating gastrointestinal disease and its application
CN110236034A (en) * 2019-06-26 2019-09-17 佛山市绿康宝保健食品有限公司 A kind of herbal composite for coordinating intestines and stomach

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1114433C (en) * 2000-12-22 2003-07-16 张志祥 Medical capsule for invigorating function of spleen and its preparing process

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103005264A (en) * 2012-12-28 2013-04-03 深圳市深博泰生物科技有限公司 Chitosan oligosaccharide-containing healthcare food and preparation method thereof
CN104140905A (en) * 2013-05-11 2014-11-12 陈洪波 Digestion helping and stomach strengthening beer
CN103416671A (en) * 2013-08-05 2013-12-04 赵杏珍 Medicinal and edible noodle capable of regulating stomach and intestine
CN104623478A (en) * 2015-01-23 2015-05-20 广州中医药大学 Medicine for regulating spleen-deficiency syndrome type intestinal bacilli illness and preparation method thereof
CN104623478B (en) * 2015-01-23 2017-11-10 广州中医药大学 A kind of medicine for adjusting syndrome of spleen deficiency intestinal bacilli illness and preparation method thereof
CN105012672A (en) * 2015-07-29 2015-11-04 青岛蓝盛洋医药生物科技有限责任公司 Traditional Chinese medicine composition for treating gastrointestinal dysfunction and preparation method of traditional Chinese medicine composition
CN106344863A (en) * 2016-08-30 2017-01-25 广州领康科技有限公司 Fructus amomi and hericium erinaceus tablet candy for targeted repairing of stomach
CN107661434A (en) * 2017-08-17 2018-02-06 福建省招宝生态农庄有限公司 A kind of medicine for eliminating pig abdominal distension grave illness and application
CN109287921A (en) * 2018-09-29 2019-02-01 首益特殊医学用途配方食品科技研究(北京)有限公司 Diet therapy nutritional element solid beverage and preparation method thereof for inflammatory bowel disease
CN109568528A (en) * 2019-01-22 2019-04-05 北京朋烨盛世生物科技有限公司 A kind of Chinese medicine composition that treating gastrointestinal disease and its application
CN110236034A (en) * 2019-06-26 2019-09-17 佛山市绿康宝保健食品有限公司 A kind of herbal composite for coordinating intestines and stomach

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Granted publication date: 20070829

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