CN105012672A - Traditional Chinese medicine composition for treating gastrointestinal dysfunction and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating gastrointestinal dysfunction and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating gastrointestinal dysfunction and a preparation method of the traditional Chinese medicine composition, belonging to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 9-30 parts of radix codonopsis, 6-15 parts of astragalus, 15-30 parts of Chinese yams, 3-9 parts of pinellia ternata, 1-4 parts of intermediate luculia flowers or fruits, 3-6 parts of fennel, 9-15 parts of white hyacinth beans, 4-9 parts of radix glehniae, 10-15 parts of radix ophiopogonis, 4-9 parts of semen raphani, 4-9 parts of pericarpium arecae, 6-15 parts of Chinese dates and 1-10 parts of liquorice. The traditional Chinese medicine composition has the effects of promoting digestion and eliminating distension, invigorating the spleen for eliminating dampness as well as regulating qi and harmonizing the stomach and also has the advantages of good curative effect, low side effect and the like.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine composition and method of making the same for the treatment of gastrointestinal dysfunction.
Background technology
Functional gastrointestinal disorder, also known as gastrointestinal neurosis, is the general name of one group of gastrointestinal syndrome.How slow gastrointestinal dysfunction onset is, clinical manifestation is based on gastrointestinal symptom, the patient of stomach neurosis shows as more: glutted after burning sensation under acid regurgitation, belch, anorexia, Nausea and vomiting, xiphoid-process, food, epigastric discomfort or pain, whenever emotion changes then exacerbation of symptoms.Intestinal neurosis, also known as irritable bowel syndrome, is the modal functional disease of gastrointestinal tract.Based on bowel symptoms, can lay one's hand on and streak swollen thing when patient often has stomachache, abdominal distention, borborygmus, diarrhoea and constipation, lower-left to suffer from abdominal pain, stomachache often increases the weight of because of feed or cold drink, alleviates after defecation, aerofluxus, coloclysis.Stomachache often with abdominal distention, defecation not freely sense or defecation frequency increase, feces such as rarely can to do at the symptom.This is claimed to be colon dysfunction, spastic colon, adaptive colitis, spastic colitis, mucus colitis, emotional diarrhea etc. in the past.The course of disease is often for years, in persistence or there is recurrent exerbation.
The cause of disease of functional gastrointestinal disorder mainly contains several aspect: 1, diet is irregular, causes the wriggling function of stomach disorderly, promotes the secretion of gastric juice, cause gastritis or gastric ulcer in the course of time.2, pathologic reason, as dyspepsia, gastritis, Peptic Ulcers, acute gastroenteritis etc.3, Nervous and Mental Factors, as the difficulty in nervous, anxiety, life and work, worry, accident misfortune etc., all can disturb the normal activity of higher nerve, and then cause gastrointestinal dysfunction.Theory of Chinese medical science is thought, The spleen and stomach provide the material basis of the acquired, source of generating QI and blood.Eating and drinking without temperance, cold-damp is lacked of proper care, and preference is pungent, tobacco and wine, surfeit delicious food savoury, abuse chemical drugs, or work strain, work and rest irregular, and chronic anxiety is melancholy, mood is smooth, emotional maladjustment etc., all can impairing the spleen and stomach, causes mechanism of qi block and occur above malaise symptoms.
The medicine of current treatment gastrointestinal dysfunction is divided into a few class: the first kind is relieving spasm to stop pain medicine, as belladonna, atropine; Equations of The Second Kind is tranquilizer, as chlordiazepoxide, stable, chlorpromazine, phenobarbital; 3rd class is nervous vomiting medicine, as vitamin B6, if vomiting is acutely taken the circumstances into consideration to give promethazine, motilium etc.But these Western medicine can stimulate the intestines and stomach of patient to a certain extent, patient is likely caused to produce untoward reaction.
Chinese patent 201010174370.9 discloses a kind of Chinese medicine composition for the treatment of gastrointestinal dysfunction, this Chinese medicine composition is prepared from by the raw material of following weight portion: Rhizoma Atractylodis Macrocephalae extract 1-6 part, Radix Paeoniae Alba extract 1-4 part, Pericarpium Citri Reticulatae extract 1-3 part, Radix Saposhnikoviae extract 1-3 part, this Chinese medicine composition has the effect regulating gastrointestinal function.
Summary of the invention
The present invention overcomes the deficiencies in the prior art, provide a kind of Chinese medicine composition for the treatment of gastrointestinal dysfunction, this Chinese medicine composition has effect of the de-swelling that helps digestion, invigorating the spleen for eliminating dampness, regulating qi-flowing for harmonizing stomach, also there is the advantages such as good effect, side effect be little, in addition, the present invention also provides corresponding manufacturing process to be made and facilitate easy-to-use preparation under the prerequisite ensureing curative effect by this Chinese medicine composition.
Chinese medicine composition of the present invention is prepared from by the raw material of following parts by weight: Radix Codonopsis 9-30 part, Radix Astragali 6-15 part, Rhizoma Dioscoreae 15-30 part, Rhizoma Pinelliae 3-9 part, Flos syringae persicae 1-4 part, Fructus Foeniculi 3-6 part, Semen Lablab Album 9-15 part, Radix Glehniae 4-9 part, Radix Ophiopogonis 10-15 part, Semen Raphani 4-9 part, Pericarpium Arecae 4-9 part, Fructus Jujubae 6-15 part and Radix Glycyrrhizae 1-10 part.
Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 9 parts, the Radix Astragali 6 parts, Rhizoma Dioscoreae 15 parts, the Rhizoma Pinelliae 3 parts, Flos syringae persicae 1 part, Fructus Foeniculi 3 parts, Semen Lablab Album 9 parts, Radix Glehniae 4 parts, Radix Ophiopogonis 10 parts, Semen Raphani 4 parts, Pericarpium Arecae 4 parts, 6 parts, Fructus Jujubae and 1 part, Radix Glycyrrhizae.
Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 30 parts, the Radix Astragali 15 parts, Rhizoma Dioscoreae 30 parts, the Rhizoma Pinelliae 9 parts, Flos syringae persicae 4 parts, Fructus Foeniculi 6 parts, Semen Lablab Album 15 parts, Radix Glehniae 9 parts, Radix Ophiopogonis 15 parts, Semen Raphani 9 parts, Pericarpium Arecae 9 parts, 15 parts, Fructus Jujubae and 10 parts, Radix Glycyrrhizae.
Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 20 parts, the Radix Astragali 10 parts, Rhizoma Dioscoreae 22 parts, the Rhizoma Pinelliae 6 parts, Flos syringae persicae 3 parts, Fructus Foeniculi 4 parts, Semen Lablab Album 12 parts, Radix Glehniae 7 parts, Radix Ophiopogonis 13 parts, Semen Raphani 7 parts, Pericarpium Arecae 7 parts, 10 parts, Fructus Jujubae and 5 parts, Radix Glycyrrhizae.
Further, described Chinese medicine composition is made into tablet, powder, capsule, granule or pill.
Accordingly, the preparation method of described Chinese medicine composition comprises following step:
Take Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, the Rhizoma Pinelliae, Flos syringae persicae, Fructus Foeniculi, Semen Lablab Album, Radix Glehniae, Radix Ophiopogonis, Semen Raphani, Pericarpium Arecae, Fructus Jujubae and Radix Glycyrrhizae, medical material is mixed, decoct with water twice, add medical material weight 8-15 water doubly at every turn, each decoction 1-3 hour, merge decocting liquid, adsorbed by D101 macroporous adsorbent resin, after decocting liquid is all by resin column, continue to rinse resin to water lotion is closely colourless with water, and then with 6-8 times of resin volume and concentration is 60-80% ethanol-eluting resin column, collect ethanol elution, decompression and solvent recovery is to dry, be ground into coarse powder, namely Chinese medicine composition of the present invention is obtained.
Source, the nature and flavor of the present invention's component used, return through and effect:
Radix Codonopsis: this product is the dry root of Campanulaceae Radix Codonopsis; Sweet in the mouth, property is put down; Return spleen, lung meridian; Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.
The Radix Astragali: this product is the root of leguminous plant Radix Hedysari multijugi; Sweet in the mouth, warm in nature; GUIXIN, lung, spleen, kidney channel; Invigorating QI to consolidate the body surface resistance, diuresis, expelling pus and toxin by strengthening QI, promoting tissue regeneration and ulcer healing.
Rhizoma Dioscoreae: this product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae; Sweet in the mouth, property is put down; Return spleen, lung, kidney channel; Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.
The Rhizoma Pinelliae: this product is the dry tuber of the aroid Rhizoma Pinelliae; Acrid in the mouth, warm in nature; Return spleen, stomach, lung meridian; Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
Flos syringae persicae: this product is the alabastrum of Oleaceae plants Persian lilac; Warm in nature, acrid in the mouth; Return stomach warp; Warming stomach for dispelling cold, stopping nausea and vomiting by lowering the adverse flow of QI.
Fructus Foeniculi: this product is the dry mature fruit of samphire Fructus Foeniculi; Acrid in the mouth, warm in nature; Return liver,kidney,spleen, stomach warp; Dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach.
Semen Lablab Album: this product is the dry mature seed of pulse family Dolichos plant Seem Lablab Album; Sweet in the mouth, slightly warm in nature; Return spleen, stomach warp; Invigorating the spleen for eliminating dampness, and in relieve summer heat.
Radix Glehniae: this product is the dry root of samphire glehnia littoralis; Sweet in the mouth, micro-hardship, cold nature; Attach to the lung and stomach meridians; Nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.
Radix Ophiopogonis: this product is the tuber of liliaceous plant Radix Liriopes, Radix Ophiopogonis seu Liriopis; Sweet in the mouth, micro-hardship, cold nature; Return lung, stomach, heart channel; YIN nourishing and the production of body fluid promoting.
Semen Raphani: this product is the dry mature seed of crucifer Radix Raphani; Acrid in the mouth, sweet, property is put down; Return lung, spleen, stomach warp; Help digestion de-swelling, lowering the adverse-rising QI to resolve phlegm.
Pericarpium Arecae: this product is the dry peel of babassu Semen Arecae; Acrid in the mouth, slightly warm in nature; Return spleen, stomach, large intestine, small intestine meridian; Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, line water detumescence.
Fructus Jujubae: this product is the dry mature fruit of Rhamnaceae jujube Fructus Jujubae; Sweet in the mouth, warm in nature; Return spleen, stomach warp; Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume; Sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Compared with prior art, the present invention has following technical advantage:
1, Chinese medicine composition of the present invention can significantly improve motilin in plasma value and the jejunum homogenate MTL value of rat, has good regulating action to the functional gastrointestinal disorder of rat, shows to have significant curative effect in treatment gastrointestinal dysfunction.
2, compared with the chemotherapeutic agent of Current therapeutic gastrointestinal dysfunction, Chinese medicine composition of the present invention is natural pure Chinese medicinal preparation, the untoward reaction that minimizing stimulating intestine and stomach causes and side effect, and Chinese medicine composition effect of the present invention is comprehensive, and medication effect is better.
The advantages such as 3, Chinese medicine composition of the present invention also has that compatibility science, preparation technology are simple, good effect, side effect are low.
Detailed description of the invention
It will be understood by those skilled in the art that technology disclosed in following examples represents the technology playing good action in the practice of the invention of the present inventor's discovery.But, many changes can be made in disclosed specific embodiments, and still obtain same or analogous result, and not depart from the spirit and scope of the present invention.
embodiment 1:the Chinese medicine granules of preparation treatment gastrointestinal dysfunction
Embodiment 1 Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 9 parts, the Radix Astragali 6 parts, Rhizoma Dioscoreae 15 parts, the Rhizoma Pinelliae 3 parts, Flos syringae persicae 1 part, Fructus Foeniculi 3 parts, Semen Lablab Album 9 parts, Radix Glehniae 4 parts, Radix Ophiopogonis 10 parts, Semen Raphani 4 parts, Pericarpium Arecae 4 parts, 6 parts, Fructus Jujubae and 1 part, Radix Glycyrrhizae.
Preparation method is as follows:
Take Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, the Rhizoma Pinelliae, Flos syringae persicae, Fructus Foeniculi, Semen Lablab Album, Radix Glehniae, Radix Ophiopogonis, Semen Raphani, Pericarpium Arecae, Fructus Jujubae and Radix Glycyrrhizae, medical material is mixed, decoct with water twice, add the water of medical material weight 8 times, each decoction 1 hour, merges decocting liquid at every turn, adsorbed by D101 macroporous adsorbent resin, after decocting liquid is all by resin column, continue to rinse resin to water lotion is closely colourless with water, and then with 6 times of resin volumes and concentration is 60% ethanol-eluting resin column, collect ethanol elution, decompression and solvent recovery, to dry, is ground into coarse powder, crosses No. five sieves, remove thick fine powder, add adjuvant, adjuvant is filler Icing Sugar and wetting agent distilled water, fine powder and filler, the amount ratio of wetting agent is 1:1:1, obtains soft material processed, and the standard of this soft material processed should be that hands is pinched agglomerating, namely light pressure falls apart, and soft material processed is put into rotary extrusion type granulator, obtains wet granular, dry under 80 DEG C of conditions, obtain dry granule, cross No. one and screen out big particle, make uniform particles, carry out quality inspection, through after the assay was approved, pack, obtain the granule of the embodiment of the present invention 1 Chinese medicine composition.
embodiment 2:the Chinese medicine granules of preparation treatment gastrointestinal dysfunction
Embodiment 2 Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 30 parts, the Radix Astragali 15 parts, Rhizoma Dioscoreae 30 parts, the Rhizoma Pinelliae 9 parts, Flos syringae persicae 4 parts, Fructus Foeniculi 6 parts, Semen Lablab Album 15 parts, Radix Glehniae 9 parts, Radix Ophiopogonis 15 parts, Semen Raphani 9 parts, Pericarpium Arecae 9 parts, 15 parts, Fructus Jujubae and 10 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 1.
embodiment 3:the Chinese powder medicine of preparation treatment gastrointestinal dysfunction
Embodiment 3 Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 20 parts, the Radix Astragali 10 parts, Rhizoma Dioscoreae 22 parts, the Rhizoma Pinelliae 6 parts, Flos syringae persicae 3 parts, Fructus Foeniculi 4 parts, Semen Lablab Album 12 parts, Radix Glehniae 7 parts, Radix Ophiopogonis 13 parts, Semen Raphani 7 parts, Pericarpium Arecae 7 parts, 10 parts, Fructus Jujubae and 5 parts, Radix Glycyrrhizae.
Preparation method is as follows:
Take Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, the Rhizoma Pinelliae, Flos syringae persicae, Fructus Foeniculi, Semen Lablab Album, Radix Glehniae, Radix Ophiopogonis, Semen Raphani, Pericarpium Arecae, Fructus Jujubae and Radix Glycyrrhizae, medical material is mixed, decoct with water twice, add the water of medical material weight 10 times at every turn, each decoction 2 hours, merge decocting liquid, adsorbed by D101 macroporous adsorbent resin, after decocting liquid is all by resin column, continue to rinse resin to water lotion is closely colourless with water, and then with 7 times of resin volumes and concentration is 70% ethanol-eluting resin column, collect ethanol elution, decompression and solvent recovery is to dry, be ground into coarse powder, cross No. five sieves, remove thick fine powder, diluent lactose is added by the equivalent method of progressively increasing, the amount ratio of fine powder and diluent is 1:100, obtain 100 times to fall apart, cross No. six sieves, obtain loose powder, carry out quality inspection, after quality inspection is qualified, packaging, obtain the powder of the embodiment of the present invention 3 Chinese medicine composition.
embodiment 4:the Chinese powder medicine of preparation treatment gastrointestinal dysfunction
Embodiment 4 Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 25 parts, the Radix Astragali 12 parts, Rhizoma Dioscoreae 28 parts, the Rhizoma Pinelliae 8 parts, Flos syringae persicae 4 parts, Fructus Foeniculi 5 parts, Semen Lablab Album 14 parts, Radix Glehniae 8 parts, Radix Ophiopogonis 12 parts, Semen Raphani 8 parts, Pericarpium Arecae 7 parts, 14 parts, Fructus Jujubae and 8 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 3.
embodiment 5:the Chinese powder medicine of preparation treatment gastrointestinal dysfunction
Embodiment 5 Chinese medicine composition is prepared from by the raw material of following parts by weight: Radix Codonopsis 12 parts, the Radix Astragali 7 parts, Rhizoma Dioscoreae 16 parts, the Rhizoma Pinelliae 4 parts, Flos syringae persicae 2 parts, Fructus Foeniculi 4 parts, Semen Lablab Album 5 parts, Radix Glehniae 6 parts, Radix Ophiopogonis 12 parts, Semen Raphani 5 parts, Pericarpium Arecae 5 parts, 7 parts, Fructus Jujubae and 3 parts, Radix Glycyrrhizae.
Preparation method is as follows with embodiment 3.
chinese medicine composition of the present invention is to the regulating action of the rat gastrointestinal tract dysfunction caused by Moxifloxacin
One, testing data
1, experimental animal: Healthy female SD rat, body weight 0.22kg-0.3kg, is provided by Zhongshan University's animal experimental center; Rat freely absorbs conventional feed and tap water, and raising room temperature is 18 DEG C-25 DEG C.
2, trial drug: the Chinese medicine composition that the embodiment of the present invention 1,3,5 prepares, trimebutine maleate table (Tianjin Tanabe Seiyaku Co., Ltd. produces, the accurate word H20030290 of traditional Chinese medicines).
Two, test method
Get SD rat 120 and be divided into 12 groups at random, 10/group, i.e. blank group, model group, positive controls, A group, B group and C group, A group is the granule that the embodiment of the present invention 1 prepares, and grinds, the high, medium and low dosage group of the furnishing that adds water, the powder that the B group embodiment of the present invention 3 prepares, the high, medium and low dosage group of the furnishing that adds water, C group is the powder that the embodiment of the present invention 5 prepares, the high, medium and low dosage group of the furnishing that adds water, concrete dosage is as shown in table 1.To blank group rats by intraperitoneal injection normal saline 0.5mg.kg/L, all the other respectively organize rat injection Moxifloxacin 0.5mg.kg/L, simultaneously to blank group and model group gavage distilled water, respectively organize the corresponding medicine of gavage to all the other.Each group of successive administration 14 days.Observe feces and the sign change of rat, and weigh body weight, the food ration of rat every day.Rat 12h fasting before test, collects following specimen by MTL radioimmunoassay kits: blood plasma, jejunal tissue store standby survey, the results are shown in Table 1.
Three, result of the test
1, general status is observed: model group rats occurs that feces is shapeless in 24h after injection Moxifloxacin, and appearance diarrhoea in various degree, crissum are filthy, occur that appetite declines thereupon, when the 7th day, loose stool more so, when the 10th day, loose stool stops gradually, feces viscous is not well, even occurs constipation, anorexia, becomes thin and day by day increases the weight of.The rat 24h major part after injection Moxifloxacin taking Chinese medicine of the present invention is all right; appetite is without obvious minimizing; wherein high dose group rat is without appearance diarrhoea; in middle dosage group and small dose group there is laxativeness in a small amount of rat; without obvious peculiar situation when the 7th day, rat normal activity when the 10th day.The rat that the gastrointestinal disorder situation of positive controls rat comparatively takes Chinese medicine of the present invention is serious.
2, MTL index:
Motilin (MTL) is one of intestinal hormone, and one of its effect promotes and affects gastrointestinal motility.Judge whether medicine has regulating action to the rat gastrointestinal tract dysfunction caused by Moxifloxacin, mainly be the degree size comparing the decline of MTL index, MTL index calibration constant value decline degree is little, prove that the functional gastrointestinal disorder of medicine to rat plays good regulating action, MTL index calibration constant value decline degree is large, proves that the regulating action of medicine to the functional gastrointestinal disorder of rat is little.
Table 1 Chinese medicine composition of the present invention is to the regulating action of rat gastrointestinal tract dysfunction
Note: compare with model group, *
p< 0.05, * *
p< 0.01.
Result show, compare with model group, Chinese medicine composition of the present invention can significantly improve rat motilin in plasma value (
p< 0.05 or
p< 0.01) and jejunum homogenate MTL value (
p< 0.01), obvious effect is all produced for the dysfunction of adjustment rat gastrointestinal tract, especially best with the effect of high dose group, show that Chinese medicine composition of the present invention has good regulating action to the rat gastrointestinal tract dysfunction caused by Moxifloxacin.Under same experiment condition, positive control drug group also can significantly improve rat motilin in plasma value (
p< 0.01) and jejunum homogenate MTL value (
p< 0.01), but effect is not so good as the effective of Chinese medicine composition high dose group of the present invention.Visible, Chinese medicine composition of the present invention has significant curative effect in treatment gastrointestinal dysfunction.
clinical observation on the therapeutic effect
1, case selection: in 120 routine gastrointestinal dysfunction clinical volunteers patients, man 60 example, female 60 example, at minimum 12 years old of age, maximum 69 years old, all patients all met gastrointestinal dysfunction symptom.
2, exclusion standard:
(1) Complicated with Severe internal medicine disease patient;
(2) drug allergy body constitution patient;
(3) gestation, women breast-feeding their children.
3, criterion of therapeutical effect:
(1) cure: appetite returns to normal level, and symptom all disappears;
(2) effective: appetite returns to normal level (normal more than 90%) substantially, and symptom disappears substantially;
(3) effective: appetite obviously increases (normal more than 30%) on the original basis, and symptom is obviously improved;
(4) invalid: appetite is without increase, and symptom is not improved;
(5) total effective rate=(curing number+effective number+efficiently individual quantity)/total number of persons * 100%.
4, instructions of taking: 120 patients are divided into 2 groups at random, often organize 60 people, be respectively treatment group and matched group, treatment group takes the powder that the embodiment of the present invention 3 prepares, every day 3 times, each 5g, continuous use one week; Matched group takes trimebutine maleate table (Tianjin Tanabe Seiyaku Co., Ltd. produces, the accurate word H20030290 of traditional Chinese medicines), every day 3 times, each 1-2 sheet, continuous use 2 weeks.
5, therapeutic outcome:
The cure rate of traditional Chinese medicine composition for treating group of the present invention is 78%, and total effective rate is 93%, higher than the cure rate of matched group 60% and the total effective rate of 71%.Visible, Chinese medicine composition of the present invention particularly the embodiment of the present invention 3 prepare curative effect of medication good, cure rate is high, can as treatment gastrointestinal dysfunction drug use.
Claims (6)
1. treat a Chinese medicine composition for gastrointestinal dysfunction, it is characterized in that being made up of the raw material of following weight portion: Radix Codonopsis 9-30 part, Radix Astragali 6-15 part, Rhizoma Dioscoreae 15-30 part, Rhizoma Pinelliae 3-9 part, Flos syringae persicae 1-4 part, Fructus Foeniculi 3-6 part, Semen Lablab Album 9-15 part, Radix Glehniae 4-9 part, Radix Ophiopogonis 10-15 part, Semen Raphani 4-9 part, Pericarpium Arecae 4-9 part, Fructus Jujubae 6-15 part and Radix Glycyrrhizae 1-10 part.
2. the Chinese medicine composition for the treatment of gastrointestinal dysfunction as claimed in claim 1, is characterized in that being made up of the raw material of following weight portion: Radix Codonopsis 9 parts, the Radix Astragali 6 parts, Rhizoma Dioscoreae 15 parts, the Rhizoma Pinelliae 3 parts, Flos syringae persicae 1 part, Fructus Foeniculi 3 parts, Semen Lablab Album 9 parts, Radix Glehniae 4 parts, Radix Ophiopogonis 10 parts, Semen Raphani 4 parts, Pericarpium Arecae 4 parts, 6 parts, Fructus Jujubae and 1 part, Radix Glycyrrhizae.
3. the Chinese medicine composition for the treatment of gastrointestinal dysfunction as claimed in claim 1, is characterized in that being made up of the raw material of following weight portion: Radix Codonopsis 30 parts, the Radix Astragali 15 parts, Rhizoma Dioscoreae 30 parts, the Rhizoma Pinelliae 9 parts, Flos syringae persicae 4 parts, Fructus Foeniculi 6 parts, Semen Lablab Album 15 parts, Radix Glehniae 9 parts, Radix Ophiopogonis 15 parts, Semen Raphani 9 parts, Pericarpium Arecae 9 parts, 15 parts, Fructus Jujubae and 10 parts, Radix Glycyrrhizae.
4. the Chinese medicine composition for the treatment of gastrointestinal dysfunction as claimed in claim 1, is characterized in that being made up of the raw material of following weight portion: Radix Codonopsis 20 parts, the Radix Astragali 10 parts, Rhizoma Dioscoreae 22 parts, the Rhizoma Pinelliae 6 parts, Flos syringae persicae 3 parts, Fructus Foeniculi 4 parts, Semen Lablab Album 12 parts, Radix Glehniae 7 parts, Radix Ophiopogonis 13 parts, Semen Raphani 7 parts, Pericarpium Arecae 7 parts, 10 parts, Fructus Jujubae and 5 parts, Radix Glycyrrhizae.
5. the Chinese medicine composition for the treatment of gastrointestinal dysfunction as claimed in claim 1, is characterized in that: described Chinese medicine composition is tablet, powder, capsule, granule or pill.
6. one kind prepare as arbitrary in claim 1-5 as described in the method for Chinese medicine composition for the treatment of gastrointestinal dysfunction, it is characterized in that comprising the steps: to take Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, the Rhizoma Pinelliae, Flos syringae persicae, Fructus Foeniculi, Semen Lablab Album, Radix Glehniae, Radix Ophiopogonis, Semen Raphani, Pericarpium Arecae, Fructus Jujubae and Radix Glycyrrhizae, medical material is mixed, decoct with water twice, add medical material weight 8-15 water doubly at every turn, each decoction 1-3 hour, merge decocting liquid, adsorbed by D101 macroporous adsorbent resin, after decocting liquid is all by resin column, continue to rinse resin to water lotion is closely colourless with water, and then with 6-8 times of resin volume and concentration is 60-80% ethanol-eluting resin column, collect ethanol elution, decompression and solvent recovery is to dry, be ground into coarse powder, namely described Chinese medicine composition is obtained.
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| CN1413681A (en) * | 2002-11-05 | 2003-04-30 | 常健 | Medicine for treating stomach trouble |
| CN1785419A (en) * | 2005-07-28 | 2006-06-14 | 江西汇仁药业有限公司 | Agastachel patchouli qi-righting fast dispersion solid preparation and its preparation method |
| CN101391088A (en) * | 2008-10-22 | 2009-03-25 | 付道成 | Enterogastritis oral medicine |
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