CN103520652A

CN103520652A - Traditional Chinese medicine composition for treating liver cancer

Info

Publication number: CN103520652A
Application number: CN201310508364.6A
Authority: CN
Inventors: 马荣康
Original assignee: Individual
Current assignee: Chen Jingjing
Priority date: 2013-10-25
Filing date: 2013-10-25
Publication date: 2014-01-22
Anticipated expiration: 2033-10-25
Also published as: CN103520652B

Abstract

The invention discloses a traditional Chinese medicine composition for treating liver cancer. The traditional Chinese medicine composition for treating the liver cancer is prepared from the following medicinal raw materials by weight: 3-8g of rhizoma sparganii, 15-25g of curcuma zedoary, 10-20g of Chinese polyphaga, 10-25g of oldenlandia diffusa, 17-28g of sculellaria barbata, 5-10g of semen vaccariae, 5-15g of fructus polygoni orientalis and 6-15g of perfoliote knotweed herb. The traditional Chinese medicine composition for treating the liver cancer has the beneficial effects that the traditional Chinese medicine composition is specially used for treating the liver cancer, multiple medicines are appropriately combined, the curative effect of the traditional Chinese medicine composition is improved by using the mutual synergistic effect or resistance effect among the medicines so as to adapt to the treatment requirements of complex illness states, adverse reactions are reduced, and the traditional Chinese medicine composition has an obvious curative effect, good absorption effect without side effects and a better treatment effect on the liver lung and is safe, reliable, simple to prepare and take and beneficial to the timely alleviation of symptoms of diseases of patients.

Description

A kind of Chinese medicine composition of Hepatoma therapy

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition of Hepatoma therapy.

Background technology

Hepatocarcinoma (liver cancer) is the third-largest common cancer that mortality rate is only second to gastric cancer, esophageal carcinoma, initial stage symptom not obvious, late period main manifestations be liver pain, weak, become thin, the symptom such as jaundice, ascites.The pathomechanism of hepatocarcinoma comprises in the evil malicious invasion of six climate exopathogens, exogenous pathogen, evil solidifying poison is tied, with the passing of time become long-pending, and internal organs Qi and blood deficiency, stagnation of dampness due to deficiency of the spleen, and qi depression to blood stasis, illustrates hepatocarcinoma except outside the Pass having with hepatitis and extraneous poisonous factor, also declines relevant with autoimmunity.Generally take clinically operation, chemicotherapy and the Chinese Medicine and Clavicular therapy of doctor trained in Western medicine, but patients with terminal because of cancerous cell diffusion cure rate lower, therefore to accomplish early discovery, early diagnosis, the early treatment of hepatocarcinoma.Carry out the prevention work of hepatocarcinoma, adhere to the prevention of hcc seven word policies of " Guan Shui, pipe grain, anti-hepatitis ".China mainly depends on operation, radiotherapy and chemotherapy aspect Hepatoma therapy, but said method is when killing cancerous cell, and human normal cell comes to harm too, and has the Western medicine of antitumaous effect, and side effect is large, and curative effect is not obvious, and somewhat expensive.At present, Chinese medicine in most cases can only play control action to anticancer, for cancer, although can mitigate the disease and pain, curative effect is not good enough.

In prior art, the herbal species of Hepatoma therapy is a lot, for example application number is 201110399307.X, name is called a kind of Chinese medicine of Hepatoma therapy, and its raw material is comprised of 12 taste medical materials such as Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hyperici Japonici, Radix Scutellariae, Herba Lobeliae Chinensis, Rhizoma Polygoni Cuspidati, Semen Persicae, Fructus Crataegi, Testa arachidis hypogaeae, Cortex Dictamni, Herba Hedyotidis Diffusae, Flos Carthami, Cortex Phellodendris; Application number is 201210208240.1, and name is called the Chinese medicine that is used for the treatment of hepatocarcinoma, and raw material is comprised of Chinese crude drugs such as Cutis Bufonis, Carapax Trionycis, Herb Gynostemmae Pentaphylli, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Herba Scutellariae Barbatae, Rhizoma Polygoni Cuspidati, the Radixs Astragali; From upper example, can find out, the medicine of existing Hepatoma therapy, raw material variety is various mostly, and preparation technology is comparatively complicated, adds that some raw material is rare valuable medicinal, and to cause the price of medicine higher, patient is difficult to bear.In addition, because some crude drug itself just has very large toxicity, to cause medicine with certain toxicity, often patient is produced to certain side effect.At present, there is no the medicine with same materials compatibility of the present invention.

Summary of the invention

Object of the present invention is exactly, in order to address the above problem, to provide a kind of Chinese medicine composition of Hepatoma therapy, and it has, and good effect, expense are low, the advantage such as have no side effect.

To achieve these goals, the present invention adopts following technical scheme:

A Chinese medicine composition for Hepatoma therapy, is comprised of the crude drug of following weight: Rhizoma Sparganii 3-8 gram, Rhizoma Curcumae 15-25 gram, Eupolyphaga Seu Steleophaga 10-20 gram, Herba Hedyotidis Diffusae 10-25 gram, Herba Scutellariae Barbatae 17-28 gram, Semen Vaccariae 5-10 gram, Fructus Polygoni Orientalis 5-15 gram, Herba Polygoni cymosi 6-15 gram.

Preferably, a kind of Chinese medicine composition of Hepatoma therapy, is comprised of the crude drug of following weight: Rhizoma Sparganii 6-8 gram, Rhizoma Curcumae 20-25 gram, Eupolyphaga Seu Steleophaga 15-20 gram, Herba Hedyotidis Diffusae 15-25 gram, Herba Scutellariae Barbatae 20-25 gram, Semen Vaccariae 6-8 gram, Fructus Polygoni Orientalis 10-15 gram, Herba Polygoni cymosi 6-12 gram.

More preferred, a kind of Chinese medicine composition of Hepatoma therapy, is comprised of the crude drug of following weight: 8 grams of Rhizoma Sparganii, 22 grams of Rhizoma Curcumae, 20 grams of Eupolyphaga Seu Steleophagas, 22 grams of Herba Hedyotidis Diffusaes, 22 grams of Herba Scutellariae Barbataes, 6 grams of Semen Vaccariae, 13 grams of Fructus Polygoni Orientaliss, 10 grams of Herba Polygoni cymosis.

The pharmacological action of each component is as follows:

Rhizoma Sparganii: acrid in the mouth; Puckery; Cool.Enter liver.Spleen channel.Chinese medicine is controlled lump in the abdomen, gathers distending pain over the hypochondrium, food stagnation distending pain, dysmenorrhea, amenorrhea, postnatal blood stasis stomachache, traumatic injury.Mongolian medicine is controlled cough due to lung-heat, asthma abundant expectoration, liver-heat, arteries and veins heat, the hot hectic fever due to YIN-deficiency of consumptive disease, " precious day " disease, fracture.

Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.1) removing blood stasis promoting the circulation of QI to relieve pain: this product effect is similar to Rhizoma Sparganii, but warm concerted effort is larger, can treat amenorrhea due to stagnation of blood stomachache, abdominal mass, gather.2) long-pending eliminating stagnation: the pain relieving of this product energy circulation of qi promoting removing food stagnancy, for eating accumulation, breast abdominal distention is vexed has a pain.3) removing blood stasis, women's amenorrhea, or the phlegm-damp congestion lump in the abdomen addiction piece that condenses and form.4) promoting the circulation of QI to relieve pain: be suitable for drinking and eating irregularly, the card of gastral cavity abdomen overflow pain.Suitable compatibility, deficient syndrome, the case of a physically strong patient running a high fever all can.Many raw using.

Eupolyphaga Seu Steleophaga: salty, cold; Slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.

Herba Hedyotidis Diffusae: bitter sweet, cold.Nontoxic.Enter heart channel, Liver Channel, spleen channel.Dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Be good at the multiple cancerous protuberance for the treatment of.

Herba Scutellariae Barbatae: cool in nature, mildly bitter flavor.Return lung, liver, kidney channel.Tool heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.

Semen Vaccariae: hardship, flat.Return liver, stomach warp.Promoting the circulation of blood regulating menstruation, reducing swelling and alleviating pain, the lactogenesis of invigorating blood circulation, expedite the emergence of the thymus dredging of stimulating milk secretion, puerperal.

Fructus Polygoni Orientalis: have eliminating mass and relieving fullness eliminating stagnation, clearing away heat to alleviate pain function.For mass in the abdomen abdominal distention, hepatosplenomegaly, the tuberculosis of cervical lymph nodes, quenches one's thirst, stomachache.Consumption 4.5～9g, heavy dose can be to 30g.Suitable amount used externally endure cream or smash long-pending, invigorating spleen to remove dampness.Control flank disease long-pending, dropsy, has a stomach-ache, lack of appetite abdominal distention, and acute catarrhal conjunctivitis, skin ulcer is swollen, scrofula.

Herba Polygoni cymosi: bitter in the mouth cool in nature, acid.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.

In technique scheme, Rhizoma Sparganii, Rhizoma Curcumae, Eupolyphaga Seu Steleophaga mainly play function of promoting blood circulation to disperse blood clots, can suppress neoplasm metastasis; Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Semen Vaccariae, Fructus Polygoni Orientalis, Herba Polygoni cymosi mainly play the effect of heat-clearing and toxic substances removing, control and eliminate tumor inflammation and infection around.

Beneficial effect of the present invention: Chinese medicine of the present invention is specifically designed to Hepatoma therapy, and multi-medicament is suitably coordinated, utilizes its mutual collaborative or resistant function, improve curative effect, to adapt to the treatment requirement of the complicated state of an illness, reduce untoward reaction, evident in efficacy, safe and reliable, preparation is simple, takes simple, good absorbing effect, have no side effect, be conducive to patient and alleviate in time condition of illness, hepatocarcinoma is had to good therapeutic effect.

Below in conjunction with embodiment, the invention will be further described; but be not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various modifications that creative work can make or distortion still in protection scope of the present invention.

Embodiment 1:

A Chinese medicine composition for Hepatoma therapy, is comprised of the crude drug of following weight: 3 grams of Rhizoma Sparganii, 15 grams of Rhizoma Curcumae, 10 grams of Eupolyphaga Seu Steleophagas, 10 grams of Herba Hedyotidis Diffusaes, 17 grams of Herba Scutellariae Barbataes, 5 grams of Semen Vaccariae, 5 grams of Fructus Polygoni Orientaliss, 6 grams of Herba Polygoni cymosis.

Above-mentioned raw materials is cleaned up, and dry disinfection, beats powder and mixes, and makes according to a conventional method tablet, quantitatively takes.

Embodiment 2:

A Chinese medicine composition for Hepatoma therapy, is comprised of the crude drug of following weight: 8 grams of Rhizoma Sparganii, 25 grams of Rhizoma Curcumae, 20 grams of Eupolyphaga Seu Steleophagas, 25 grams of Herba Hedyotidis Diffusaes, 28 grams of Herba Scutellariae Barbataes, 10 grams of Semen Vaccariae, 15 grams of Fructus Polygoni Orientaliss, 15 grams of Herba Polygoni cymosis.

Embodiment 3:

A Chinese medicine composition for Hepatoma therapy, is comprised of the crude drug of following weight: 8 grams of Rhizoma Sparganii, 22 grams of Rhizoma Curcumae, 20 grams of Eupolyphaga Seu Steleophagas, 22 grams of Herba Hedyotidis Diffusaes, 22 grams of Herba Scutellariae Barbataes, 6 grams of Semen Vaccariae, 13 grams of Fructus Polygoni Orientaliss, 10 grams of Herba Polygoni cymosis.

Clinical data:

(1) clinical data

The inventor carries out clinical observation treatment to 100 routine liver cancer patients, total effective rate 87%.By cytodiagnosis, blood routine examination, hepatic and renal function checks, regularly carrying out the imaging examinations such as rabat, CT, B ultrasonic, three months is a course for the treatment of, takes medicine one more than the course for the treatment of, patient's lump of 74% reduces more than 50%, wherein patient's lump of 42% is eliminated completely, patient is had good QI invigorating, enriches blood, regulates the functions such as immunity simultaneously, weak, the alopecia that patient after Prophylactic chemotherapy is occurred, feels sick and the General Symptoms such as leukopenia has good prevention and alleviates effect.

(2) Therapeutic Method

Warm water is taken after mixing it with water, and one day twice, the tablet of each 3 embodiment of the present invention, 3 developments.According to conditions of patients weight, calculate treatment time, patients with mild was taken about 3 months, and severe case serve on 12 months and can fully recover.

(3) curative effect determinate standard

" alleviate completely ": tumor disappears completely, more than maintaining surrounding;

" partial rcsponse ": tumor is dwindled more than 50%, maintains surrounding;

" stablize ": tumor is dwindled not as good as 50%, increases and is no more than 25%;

" deterioration ": tumor increases more than 25%.

(4) therapeutic effect:

Clinical complete remission 45 examples, account for 45%; Partial rcsponse 25 examples, account for 25%; Stablize 17 examples, account for 17%; Worsen 13 examples, total effective rate 87%.

The present invention prepares simply, and good absorbing effect is evident in efficacy, has no side effect, safe, is conducive to patient and alleviates in time condition of illness.

Model case:

1, Wang, 51 years old is the hepatocarcinoma initial stage by hospital diagnosis, takes the made tablet of the embodiment of the present invention 3, warm water is taken after mixing it with water, and one day twice, each 4 tablets, basic recovery normally, continues to take inspection after four months after two months, recovers normal.

2, Lee, 58 years old is hepatocarcinoma mid-term by hospital diagnosis, takes the made tablet of the embodiment of the present invention 3, warm water is taken after mixing it with water, and one day twice, each 4 tablets, stable disease after three months, continues to take four months, basic recovery normally.

3, grandson, 55 years old is later period of hepatocarcinoma by hospital diagnosis, takes the made tablet of the embodiment of the present invention 3, and warm water is taken after mixing it with water, and one day twice, each 4 tablets, checked after 5 months, stable disease, continues to take 5 months, and lump dwindles, and cancerous cell has no diffusion.

Claims

1. a Chinese medicine composition for Hepatoma therapy, is characterized in that, consists of: Rhizoma Sparganii 3-8 gram, Rhizoma Curcumae 15-25 gram the crude drug of following weight, Eupolyphaga Seu Steleophaga 10-20 gram, Herba Hedyotidis Diffusae 10-25 gram, Herba Scutellariae Barbatae 17-28 gram, Semen Vaccariae 5-10 gram, Fructus Polygoni Orientalis 5-15 gram, Herba Polygoni cymosi 6-15 gram.

2. a kind of Chinese medicine composition of Hepatoma therapy as claimed in claim 1, is comprised of the crude drug of following weight: Rhizoma Sparganii 6-8 gram, Rhizoma Curcumae 20-25 gram, Eupolyphaga Seu Steleophaga 15-20 gram, Herba Hedyotidis Diffusae 15-25 gram, Herba Scutellariae Barbatae 20-25 gram, Semen Vaccariae 6-8 gram, Fructus Polygoni Orientalis 10-15 gram, Herba Polygoni cymosi 6-12 gram.

3. a kind of Chinese medicine composition of Hepatoma therapy as claimed in claim 1, is characterized in that, consists of: 8 grams of Rhizoma Sparganii, 22 grams of Rhizoma Curcumae the crude drug of following weight, 20 grams of Eupolyphaga Seu Steleophagas, 22 grams of Herba Hedyotidis Diffusaes, 22 grams of Herba Scutellariae Barbataes, 6 grams of Semen Vaccariae, 13 grams of Fructus Polygoni Orientaliss, 10 grams of Herba Polygoni cymosis.