CN107468805A - A kind of endo-medicine for treating children's exogenous fever and preparation method thereof - Google Patents
A kind of endo-medicine for treating children's exogenous fever and preparation method thereof Download PDFInfo
- Publication number
- CN107468805A CN107468805A CN201710879872.3A CN201710879872A CN107468805A CN 107468805 A CN107468805 A CN 107468805A CN 201710879872 A CN201710879872 A CN 201710879872A CN 107468805 A CN107468805 A CN 107468805A
- Authority
- CN
- China
- Prior art keywords
- medicine
- fever
- schizonepeta
- endo
- children
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 title claims abstract description 48
- 206010037660 Pyrexia Diseases 0.000 title claims abstract description 46
- 238000002360 preparation method Methods 0.000 title description 9
- 241000951473 Schizonepeta Species 0.000 claims abstract description 20
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 12
- 206010004542 Bezoar Diseases 0.000 claims abstract description 12
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229940041616 menthol Drugs 0.000 claims abstract description 12
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 11
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 11
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 11
- 244000111489 Gardenia augusta Species 0.000 claims abstract description 11
- 235000018958 Gardenia augusta Nutrition 0.000 claims abstract description 11
- 235000004347 Perilla Nutrition 0.000 claims abstract description 11
- 244000124853 Perilla frutescens Species 0.000 claims abstract 4
- 230000000694 effects Effects 0.000 description 14
- 239000000796 flavoring agent Substances 0.000 description 14
- 235000019634 flavors Nutrition 0.000 description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 201000010099 disease Diseases 0.000 description 9
- 208000032843 Hemorrhage Diseases 0.000 description 7
- 241000229722 Perilla <angiosperm> Species 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 230000000740 bleeding effect Effects 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 206010007247 Carbuncle Diseases 0.000 description 5
- 206010019233 Headaches Diseases 0.000 description 5
- 231100000869 headache Toxicity 0.000 description 5
- 206010033675 panniculitis Diseases 0.000 description 5
- 210000000697 sensory organ Anatomy 0.000 description 5
- 210000004304 subcutaneous tissue Anatomy 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 208000035861 hematochezia Diseases 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 239000002574 poison Substances 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 206010008190 Cerebrovascular accident Diseases 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 208000034507 Haematemesis Diseases 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 208000015817 Infant Nutrition disease Diseases 0.000 description 3
- 208000006011 Stroke Diseases 0.000 description 3
- 206010046788 Uterine haemorrhage Diseases 0.000 description 3
- 208000034158 bleeding Diseases 0.000 description 3
- 230000036760 body temperature Effects 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 208000021760 high fever Diseases 0.000 description 3
- 238000002386 leaching Methods 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- 244000056139 Brassica cretica Species 0.000 description 2
- 235000003351 Brassica cretica Nutrition 0.000 description 2
- 235000003343 Brassica rupestris Nutrition 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- 208000037093 Menstruation Disturbances Diseases 0.000 description 2
- 206010027339 Menstruation irregular Diseases 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- 206010044684 Trismus Diseases 0.000 description 2
- 235000001667 Vitex agnus castus Nutrition 0.000 description 2
- 244000063464 Vitex agnus-castus Species 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 206010000269 abscess Diseases 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 208000002399 aphthous stomatitis Diseases 0.000 description 2
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000001079 digestive effect Effects 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 208000014617 hemorrhoid Diseases 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 244000000053 intestinal parasite Species 0.000 description 2
- 201000007227 lymph node tuberculosis Diseases 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 235000010460 mustard Nutrition 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 230000035935 pregnancy Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 208000005687 scabies Diseases 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 206010042772 syncope Diseases 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010016326 Feeling cold Diseases 0.000 description 1
- 241000881853 Galaxias maculatus Species 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010034568 Peripheral coldness Diseases 0.000 description 1
- 206010034829 Pharyngeal oedema Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000012287 Prolapse Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 241000593989 Scardinius erythrophthalmus Species 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 208000030208 low-grade fever Diseases 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 201000002266 mite infestation Diseases 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000023409 throat pain Diseases 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 235000020985 whole grains Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Physiology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of endo-medicine for treating children's exogenous fever according to the understanding mechanism of Chinese traditional treatment children's exogenous fever, each component and its mass parts ratio of the medicine are as follows:15~35g of cow-bezoar, 15~70g of cassia twig, 35~120g of radix bupleuri, 50~150g of perilla leaf, 150~300g of honeysuckle, 30~120g of folium artemisiae argyi, 80~160g of schizonepeta, 80~160g of cape jasmine 50~120g schizonepeta, 60~150g of Radix picrorrhizae, 0.25~1.5g of menthol, medicine provided by the invention are a good Chinese prescriptions.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of endo-medicine for treating children's exogenous fever, particularly
The field of the endo-medicine used for children's exogenous fever patient and preparation method thereof.
Background technology
Doctor thinks:Fever caused by exogenous pathogens refers to the heresy for experiencing the six external factors which cause diseases or warms the gas of epidemic disease poison, causes battalion to defend and becomes estranged, internal organs negative and positive
Imbalance, there is the rise of pathologic body temperature, with a kind of exterior syndrome that aversion to cold, flushing, agitation, rapid pulse etc. are main clinical manifestation
Card.Fever caused by exogenous pathogens, ancient times normal name is " heating ", " fever and chills ", " high fever " etc..
Clinical manifestation:The form of expression of fever caused by exogenous pathogens is more, but body temperature rise, body is warm, flushing, tongue is red, rapid pulse etc. is it
Basic Clinical symptoms.Fever caused by exogenous pathogens onset is hurried, has moderate heating or the high fever of 2 weeks or so, it is low-grade fever also to have a few diseases more
Person.Heat type have fever with chilliness, fever without chill, hectic fever, body high fever, hiding fever, fevers and chills alternate, hectic fever etc..Fever time,
Short person moves back for several days, and elder continued for more than 10 days or longer time calorific potential is not understood.Most often with seeing dry polydipsia, oliguria constipation, on tongue
The disease of the heat consuming body fluids such as few Tianjin.In addition to heating, the symptom of lesion correlation visceral dysfunction, such as cough, pectoralgia, the side of body must be accompanied by
Rib turgor, constipation, diarrhea, urine are frequently anxious etc..
So, it is people in the art with regard to how to find a kind of Chinese medicine composition that can effectively treat children's exogenous fever
The problem of member is urgently to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, on treatment children's exogenous fever, during people gradually appreciate
Cure the advantages for the treatment of children's exogenous fever, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing
There is a present situation of western medical treatment children's exogenous fever, the purpose of the present invention is to be to provide a kind of to treat for oral administration of children's exogenous fever
Medicine, to solve the problems, such as that children's exogenous fever patient gets well early.The medicine is using common Chinese medicine as raw material, is passed through
Rational medicine and its mass parts ratio are selected, can effectively be controlled
Treat above-mentioned children's exogenous fever.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:One kind is provided and treats children's exogenous hair
Endo-medicine of heat and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows:
15~35g of cow-bezoar, 15~70g of cassia twig, 35~120g of radix bupleuri, 50~150g of perilla leaf, 150~300g of honeysuckle, folium artemisiae argyi 30
~120g, 80~160g of schizonepeta, 80~160g of cape jasmine 50~120g schizonepeta, 60~150g of Radix picrorrhizae, 0.25~1.5g of menthol.
A kind of endo-medicine for treating children's exogenous fever and preparation method thereof, it is characterised in that the medicine it is each
Component and its mass parts are than as follows:
18~32g of cow-bezoar, 18~60g of cassia twig, 32~105g of radix bupleuri, 58~130g of perilla leaf, 180~260g of honeysuckle, folium artemisiae argyi 38
~105g, 90~130g of schizonepeta, 90~130g of cape jasmine 58~105g schizonepeta, 70~130g of Radix picrorrhizae, 0.28~1.2g of menthol.
A kind of endo-medicine for treating children's exogenous fever and preparation method thereof, it is characterised in that the medicine it is each
Component and its mass parts are than as follows:
Cow-bezoar 26g, cassia twig 50g, radix bupleuri 95g, perilla leaf 115g, honeysuckle 230g, folium artemisiae argyi 95g, schizonepeta 115g, cape jasmine 95g schizonepeta
115g, Radix picrorrhizae 115g, menthol 1g.
A kind of endo-medicine for treating children's exogenous fever and preparation method thereof, it is characterised in that methods described is included such as
Lower step is prepared:
A, except cow-bezoar and menthol(Grind as superfine end)Outside, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, according to mass parts
Decocted a drug wrapped than being respectively crushed into coarse;
B, the raw material Chinese medicine wrapped is put into after soaking 30min in cold boiling water, then soaked medicine is put into marmite and decocted
Three times:1. first time amount of water is 9~10 times of medicinal material total amount, first high heat decoction, when 15min is arrived in decoction, turns slow fire and boil
120 min, leaching decoction;2. second of amount of water is 8~9 times of dry dregs of a decoction total amount, first high heat decoction, waits to decoct and arrive 10min
When, turn slow fire and boil 110 min, leaching decoction;3. third time amount of water is 7~8 times of dry dregs of a decoction total amount, first high heat decoction,
When 8min is arrived in decoction, turn slow fire and boil 100 min, leaching decoction;4. above-mentioned filtrate three times is mixed with the superfine end in " A "
Mix the clear cream for, being concentrated under reduced pressure into that relative density is 1.10~1.3 (80 DEG C).
C, by the clear cream prepared in above-mentioned " B " drying, sterilization, and superfine end is ground into according to mass parts ratio, this is made
The active component of invention medicine;
D, according to tradition prepare Chinese herbal granules method, added into above-mentioned well mixed active component appropriate dextrin,
Sucrose and water, are well mixed again, and then granulation, drying, whole grain, quality examination, divided dose, produce granules medicine.
A kind of endo-medicine for treating children's exogenous fever and preparation method thereof, it is characterised in that the instructions of taking is:
The granules medicine prepared is taken with daily 1~2 time, once a dose sooner or later, dosage 5g/ times, warm water delivery service.3 days
For a course for the treatment of, 1~2 course for the treatment of of taking medicine, on inspection:Body temperature is normal, physical recovery health.
Each raw material Chinese medicine in prescription of the present invention has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine
Record.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Cow-bezoar, nature and flavor:It is bitter, sweet, cool in nature, there is the effect of cool liver that clears away heart-fire, eliminate phlegm for resuscitation, be clearing heat and detoxicating, for treating pyreticosis
Coma, apoplexy key close, twitch, acute infantile convulsion, throat swell rotten, aphthae, ulcer serious case of furuncle;
Cassia twig, nature and flavor:It is pungent, sweet, warm-natured, there is the effect of expelling cold and relieving exterior syndrome, warming meridian, activating YANG and prormoting functioning of QI, for treating chill table
Card, numbness and ache of cold dampness, peripheral coldness, closed dysmenorrhea, abdominal mass caking, the obstruction of qi in the chest, palpitaition, phlegm and retained fluid, difficult urination;
Radix bupleuri, nature and flavor:It is bitter, cool, have and inducing diaphoresis in, soothing the liver, rising Yang the effect of, for treating fevers and chills alternate, fullness in the chest and hypochondriac pain, mouth
Bitter deafness, headache and dizziness, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis;
Perilla leaf, nature and flavor:It is acrid flavour, warm-natured, have expelling cold and relieving exterior syndrome, ventilating the lung and resolving phlegm, promoting the circulation of qi and in, antiabortive, cowfish crab poison the effect of, use
Disliked in treatment exterior syndrome due to wind-cold, coughing with a lot of sputum, crisp turgor, nausea and vomiting, stomachache vomiting and diarrhoea, nausea discord, gestation in cloudy, ichthyophagy crab
Poison;
Honeysuckle, nature and flavor:It is sweet, cold, have it is clearing heat and detoxicating the effect of, for treat warm disease heating, toxic-heat and blood stasis, carbuncle swells furunculosis,
Larynx numbness and multi-infection disease;
Folium artemisiae argyi, nature and flavor:It is acrid flavour, hardship, warm-natured, there is the effect of warming channel for arresting bleeding, eliminating cold to stop pain, removing dampness to stop itchin, for treat spit blood,
Bleeding from five sense organs or subcutaneous tissue, painstaking blood, have blood in stool, have blood in stool, uterine bleeding, gestation hemorrhage, irregular menstruation, dysmenorrhoea, fetal irritability, trusted subordinate's crymodynia, diarrhea protracted dysentery,
Under choleraic myospasm, band, the disease such as eczema, mange, hemorrhoid, large carbuncle;
Schizonepeta, nature and flavor:It is pungent, warm, have deliver, wind-dispelling, regulating blood condition, fries charcoal hemostasis the effect of, for treat cold, fever, headache,
Abscess of throat, apoplexy lockjaw, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, postpartum anemic fainting, carbuncle swells, sore scabies, the disease such as scrofula;
Cape jasmine, nature and flavor:It is bitter, cold, there is the effect of purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body, for treating Vexed, liver
Fiery hot eyes, headache, damp and hot yellow infantile malnutrition due to digestive disturbances or intestinalparasites, stranguria, leaf blood bleeding from five sense organs or subcutaneous tissue, bloody flux hematuria, aphthae, sore swollen toxin, strain swelling and pain;
Schizonepeta, nature and flavor:It is pungent, warm, have deliver, wind-dispelling, regulating blood condition, fries charcoal hemostasis the effect of, for treat cold, fever, headache,
Abscess of throat, apoplexy lockjaw, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, postpartum anemic fainting, carbuncle swells, sore scabies, the disease such as scrofula;
Radix picrorrhizae, nature and flavor:It is bitter, cold in nature, there is the effect of reducing the asthenic fever, the infantile malnutrition due to digestive disturbances or intestinalparasites that disappears heat, heat-clearing and damp-drying drug, purging intense heat and detonicating, for treating
Deficiency of Yin hectic fever due to yin, hectic fever night sweat, infant malnutrition, damp-heat dysentery, jaundice, haematemesis, bleeding from five sense organs or subcutaneous tissue, red eye, swell pain, carbuncle swells sore, hemorrhoid swell
Poison;
Menthol, nature and flavor:It is acrid flavour, cool in nature, there is dispelling wind, heat-clearing to imitate, for treating anemopyretic cold, headache, hot eyes, throat
Swelling and pain, dentalgia, pruitus.
Medicine of the present invention is the principle based on Chinese traditional treatment children's exogenous fever, from the pathology machine according to children's exogenous fever
System and pharmacological action are thought:With regard to children's exogenous fever, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, to upper
Stating disease has good effect.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned children's exogenous fever, using the formula system
Standby medicine effect is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the present invention's
Embodiment is described in further detail:
Embodiment 1:
A kind of endo-medicine for treating children's exogenous fever, it is characterised in that each component and its mass parts ratio of the medicine
It is as follows:
Cow-bezoar 26g, cassia twig 50g, radix bupleuri 95g, perilla leaf 115g, honeysuckle 230g, folium artemisiae argyi 95g, schizonepeta 115g, cape jasmine 95g schizonepeta
115g, Radix picrorrhizae 115g, menthol 1g.
Embodiment 2:
A kind of endo-medicine for treating children's exogenous fever, it is characterised in that each component and its mass parts ratio of the medicine
It is as follows:
Cow-bezoar 32g, cassia twig 60g, radix bupleuri 105g, perilla leaf 130g, honeysuckle 260g, folium artemisiae argyi 105g, schizonepeta 130g, cape jasmine 105g chaste trees
Mustard 130g, Radix picrorrhizae 130g, menthol 1.2g.
Embodiment 3:
A kind of endo-medicine for treating children's exogenous fever, it is characterised in that each component and its mass parts ratio of the medicine
It is as follows:
Cow-bezoar 35g, cassia twig 70g, radix bupleuri 120g, perilla leaf 150g, honeysuckle 300g, folium artemisiae argyi 120g, schizonepeta 160g, cape jasmine 120g chaste trees
Mustard 160g, Radix picrorrhizae 150g, 0.25~1.5g of menthol.
Model case
Through clinical conditions children's exogenous fever patient totally 1120, the age is 610 of more than 3 years old, and only 510 are 3
Year is following.850 to be fully recovered in 1120 patients, effective 270.Total effective rate is up to 98%.
Claims (3)
1. a kind of endo-medicine for treating children's exogenous fever, it is characterised in that each component and its mass parts of the medicine
Than as follows:
15~35g of cow-bezoar, 15~70g of cassia twig, 35~120g of radix bupleuri, 50~150g of perilla leaf, 150~300g of honeysuckle, folium artemisiae argyi 30
~120g, 80~160g of schizonepeta, 80~160g of cape jasmine 50~120g schizonepeta, 60~150g of Radix picrorrhizae, 0.25~1.5g of menthol.
2. it is according to claim 1 treatment children's exogenous fever endo-medicine, it is characterised in that the medicine it is each
Component and its mass parts are than as follows:
18~32g of cow-bezoar, 18~60g of cassia twig, 32~105g of radix bupleuri, 58~130g of perilla leaf, 180~260g of honeysuckle, folium artemisiae argyi 38
~105g, 90~130g of schizonepeta, 90~130g of cape jasmine 58~105g schizonepeta, 70~130g of Radix picrorrhizae, 0.28~1.2g of menthol.
3. the endo-medicine of the treatment children's exogenous fever according to claim 1 to 2, it is characterised in that the medicine
Each component and its mass parts are than as follows:
Cow-bezoar 26g, cassia twig 50g, radix bupleuri 95g, perilla leaf 115g, honeysuckle 230g, folium artemisiae argyi 95g, schizonepeta 115g, cape jasmine 95g schizonepeta
115g, Radix picrorrhizae 115g, menthol 1g.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710879872.3A CN107468805A (en) | 2017-09-26 | 2017-09-26 | A kind of endo-medicine for treating children's exogenous fever and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710879872.3A CN107468805A (en) | 2017-09-26 | 2017-09-26 | A kind of endo-medicine for treating children's exogenous fever and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107468805A true CN107468805A (en) | 2017-12-15 |
Family
ID=60586435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710879872.3A Withdrawn CN107468805A (en) | 2017-09-26 | 2017-09-26 | A kind of endo-medicine for treating children's exogenous fever and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107468805A (en) |
-
2017
- 2017-09-26 CN CN201710879872.3A patent/CN107468805A/en not_active Withdrawn
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105412749A (en) | Medicine for treating infantile pneumonia with dyspnea and cough and preparation method and application method thereof | |
CN104001045A (en) | Drug for treating dog pneumonia and preparation method thereof | |
CN103830657A (en) | Medicine for treating chronic cholecystitis | |
CN107854613A (en) | A kind of pill medicine and preparation method that can effectively treat epigastric pain | |
CN105535730A (en) | Novel traditional Chinese medicine composition for treating coughs and preparation method thereof | |
CN105233002A (en) | Traditional Chinese medicine composition for treating subacute thyroiditis | |
CN107551043A (en) | A kind of endo-medicine for treating children's exogenous fever and preparation method thereof | |
CN107468805A (en) | A kind of endo-medicine for treating children's exogenous fever and preparation method thereof | |
CN107823522A (en) | A kind of pill medicine for treating epigastric pain and preparation method thereof | |
CN107854662A (en) | A kind of Chinese medicine preparation for treating cirrhotic ascites and preparation method thereof | |
CN107233505A (en) | It is a kind of to be used to treat pill medicine of constipation and preparation method thereof | |
CN104771620A (en) | Drug for postoperative nursing after acute appendicitis surgery and preparation method thereof | |
CN104491537A (en) | Traditional Chinese medicine composition for treating rheumatic heart disease | |
CN104274627A (en) | Special traditional Chinese medicine anesthetic for surgery and preparation method thereof | |
CN107753909A (en) | A kind of endo-medicine and preparation method for treating infantile cough | |
CN107596261A (en) | A kind of Chinese medicine composition for treating taste-blindness rate and preparation method thereof | |
CN108452279A (en) | A kind of Chinese medicine composition and the preparation method and application thereof for treating flu | |
CN107496794A (en) | A kind of pill medicine for treating bronchial astehma and preparation method thereof | |
CN107789447A (en) | A kind of Chinese medicine composition and preparation method for being used to treat bronchial astehma | |
CN107243065A (en) | It is a kind of to treat Chinese medicine composition of acute bronchitis in children and preparation method thereof | |
CN101095876A (en) | Chinese medicine preparation for treating diabetes respiratory tract infection | |
CN107802805A (en) | A kind of endo-medicine and preparation method that can effectively treat infantile cough | |
CN107582826A (en) | A kind of endo-medicine for treating cough and preparation method thereof | |
CN107823468A (en) | A kind of capsule medicine and preparation method for treating the early stage of lung cancer | |
CN107596265A (en) | A kind of decoction medicine for treating dreaming often and waking easily and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20171215 |
|
WW01 | Invention patent application withdrawn after publication |