CN107823468A - A kind of capsule medicine and preparation method for treating the early stage of lung cancer - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of capsule medicine for treating the early stage of lung cancer according to the understanding mechanism of the Chinese traditional treatment early stage of lung cancer, each component and its mass parts ratio of the medicine are as follows：150~350g of dayflower, 100~160g of sub- clarinet bacterium, 150~280g of cordate houttuynia, 150~350g of Japanese Cayratia Herb, 50~120g of Chinese olive, 30~120g of tendril-leaved fritillary bulb, 150~350g of Ku Zhi, 10~40g of Oroxylum indicum, 250~550g of Chinese alpine rush, 150~300g of the root bark of Chinese wolf-berry, 60~150g of pyrrosia lingua, 30~120g of citron, 60~160g of Schizaea digitata (L.) Sw, 80~160g of bryozoatum, 150~350g of wide muscle rattan, 50~120g of caulis bambusae in taenian, 25~160g of aster, 80~160g of Hedge Prinsepia Nut, 80~160g of Included-in-the-Appendices cream, 30~150g of radix glycyrrhizae；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of capsule medicine and preparation method for treating the early stage of lung cancer

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating the early stage of lung cancer, particularly supply The capsule medicine and the field of preparation method that early stage of lung cancer patient uses.

Background technology

Doctor thinks：Lung cancer is that morbidity and mortality growth is most fast, and maximum to population health and life threat is pernicious One of tumour.Many countries all report that the morbidity and mortality of lung cancer substantially increase in the past 50 years, the male lung cancer incidence of disease First of all malignant tumours is accounted for the death rate, the women incidence of disease accounts for second, and the death rate accounts for second.The cause of disease of lung cancer So far not completely clearly, great mass of data shows, long-term a large amount of smokings and lung cancer have very close relationship.It is existing Research has shown that：The probability that long-term a large amount of smokers suffer from lung cancer is 10~20 times of non-smoker, and it is smaller to start the age of smoking, suffers from The probability of lung cancer is higher.In addition, smoking not only directly affects my health, the also health generation to surrounding population is bad Influence, cause involuntary smoker's lung cancer illness rate substantially to increase.The incidence of disease of city dweller's lung cancer is higher than rural area, and this may be with city City's atmosphere pollution with flue dust contain carcinogen it is relevant.

So, just how to find a kind of Chinese medicine composition that can effectively treat the early stage of lung cancer, be those skilled in the art urgently The problem of to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in the treatment early stage of lung cancer, people gradually appreciate middle treatment The advantages for the treatment of the early stage of lung cancer, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, control for existing doctor trained in Western medicine The present situation of the early stage of lung cancer is treated, the purpose of the present invention is to be to provide a kind of capsule medicine for treating the early stage of lung cancer, to solve morning The problem of phase patients with lung cancer is got well and extends life cycle early.The medicine is using common Chinese medicine as raw material, passes through selection Rational medicine and mass parts ratio, can effectively treat the above-mentioned early stage of lung cancer.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of early stage of lung cancer for the treatment of is provided Capsule medicine and preparation method, it is characterised in that each component and mass parts of the medicine are than as follows：

150~350g of dayflower, 100~160g of sub- clarinet bacterium, 150~280g of cordate houttuynia, 150~350g of Japanese Cayratia Herb, Chinese olive 50 ~120g, 150~350g of tendril-leaved fritillary bulb 30~120g, Ku Zhi, 10~40g of Oroxylum indicum, 250~550g of Chinese alpine rush, the root bark of Chinese wolf-berry 150~ 300g, 60~150g of pyrrosia lingua, 30~120g of citron, 60~160g of Schizaea digitata (L.) Sw, 80~160g of bryozoatum, 150~350g of wide muscle rattan, 50~120g of caulis bambusae in taenian, 25~160g of aster, 80~160g of Hedge Prinsepia Nut, 80~160g of Included-in-the-Appendices cream, 30~150g of radix glycyrrhizae, auxiliary material：Starch is fitted Amount.

A kind of capsule medicine and preparation method for treating the early stage of lung cancer, it is characterised in that each component of the medicine And mass parts are than as follows：

180~310g of dayflower, 115~140g of sub- clarinet bacterium, 180~250g of cordate houttuynia, 180~310g of Japanese Cayratia Herb, Chinese olive 58 ~105g, 180~310g of tendril-leaved fritillary bulb 38~105g, Ku Zhi, 12~35g of Oroxylum indicum, 280~480g of Chinese alpine rush, the root bark of Chinese wolf-berry 180~ 260g, 70~130g of pyrrosia lingua, 36~105g of citron, 70~140g of Schizaea digitata (L.) Sw, 90~140g of bryozoatum, 180~310g of wide muscle rattan, 58~105g of caulis bambusae in taenian, 28~140g of aster, 90~140g of Hedge Prinsepia Nut, 90~140g of Included-in-the-Appendices cream, 38~130g of radix glycyrrhizae, auxiliary material：Starch is fitted Amount.

A kind of capsule medicine and preparation method for treating the early stage of lung cancer, it is characterised in that each component of the medicine And mass parts are than as follows：

Dayflower 280g, sub- clarinet bacterium 120g, cordate houttuynia 220g, Japanese Cayratia Herb 280g, Chinese olive 95g, tendril-leaved fritillary bulb 95g, Ku Zhi 280g, wood Butterfly 31g, Chinese alpine rush 420g, root bark of Chinese wolf-berry 230g, pyrrosia lingua 118g, citron 95g, Schizaea digitata (L.) Sw 120g, bryozoatum 120g, wide muscle rattan 280g, caulis bambusae in taenian 95g, aster 120g, Hedge Prinsepia Nut 120g, Included-in-the-Appendices cream 120g, radix glycyrrhizae 118g, auxiliary material：Appropriate starch.

A kind of Chinese medicine composition and preparation method for being used to treat lung cancer, it is characterised in that methods described includes following step Suddenly it is prepared：

A, after above-mentioned all raw material Chinese medicines being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, the raw material Chinese medicine wrapped is put into after soaking 40min in cold boiling water, then soaked medicine is put into marmite and decocted Three times：1. amount of water is 9~10 times of medicinal material total amount, high heat decoction is first carried out, when 15min is arrived in decoction, turns slow fire and boils 115 Min, leaching decoction；2. amount of water is 8~9 times of dry dregs of a decoction total amount, high heat decoction is first carried out, when 10min is arrived in decoction, is turned Slow fire boils 105 min, leaching decoction；3. amount of water is 7~8 times of dry dregs of a decoction total amount, high heat decoction is first carried out, waits to decoct During to 8min, turn slow fire and boil 90 min, leaching decoction；4. merging decoction three times, and it is concentrated under reduced pressure into every milliliter contained 3g Standard after, that is, obtain drug extract.

C, by the extract dry prepared in above-mentioned B, sterilization, and it is standby according to mass parts ratio to be ground into superfine end；

D, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, by superfine myrrh thing mistake ground in C After sieve, and auxiliary material is put into medicine device and is well mixed in the lump, is then prepared into capsule（Total length after its capsule is sealed is 23.3mm, medicinal powder capacity 0.4~0.5g/ grains）, then polish, sterilize, sealed packaging produces.

A kind of capsule medicine and preparation method for treating the early stage of lung cancer, it is characterised in that the instructions of taking is：Will system The capsule medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 2g（4）/ time, half an hour temperature is opened after meal Water delivery service.60 days are a course for the treatment of, and 2 courses for the treatment of of taking medicine, symptom fades away, and life cycle was up to more than 10 months.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Dayflower, nature and flavor：It is sweet, light, cold, there is the effect of clearing heat-fire, removing toxic substances, inducing diuresis for removing edema, for treating cold, fever, heat The diseases such as sick polydipsia, abscess of throat, oedema oliguria, puckery pain of heat gonorrhea, carbuncle swells serious case of furuncle；

Sub- clarinet bacterium, nature and flavor：It is taste micro-puckery, mild-natured, there is the effect of anticancer, for treating uterine cancer；

Cordate houttuynia, nature and flavor：It is pungent, be slightly cold, have the clearing heat and detoxicating, carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia the effect of, told for treating lung carbuncle Purulence, phlegm heat panting cough, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus；

Japanese Cayratia Herb, nature and flavor：It is bitter, acid, cold in nature, there is the effect of clearing heat and promoting diuresis, removing toxicity for detumescence, for treating heat toxin carbuncle swells, malignant boil The diseases such as sore, erysipelas, abscess of throat, snake bite and insect sting, scald, arthralgia pain due to rheumatism, jaundice, rush down dysentery, gonorrhoea, hematuria；

Chinese olive, nature and flavor：It is sweet, sour, flat, there is the effect of clearing heat and detoxicating, relieving sore-throat, promote the production of body fluid, for treating abscess of throat, cough phlegm Glutinous, dysphoria and thirsty, fish and crab poisoning；

Tendril-leaved fritillary bulb, nature and flavor：Bitter, sweet, cold nature, have clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, dissipating bind disappear carbuncle the effect of, for treating lung The diseases such as hot cough caused by dryness, dry cough few phlegm, deficiency of Yin overstrain cough, blood-stained sputum, scrofula, acute mastitis, lung carbuncle；

Ku Zhi, nature and flavor：It is bitter, acid, cold in nature, there is the effect of heat-clearing, diuresis, removing toxic substances, detumescence, for treating flu, lung heat cough Cough, the disease such as abscess of throat, swelling and aching of gum, jaundice with damp-heat pathogen, dysentery, oedema, heat gonorrhea, pemphigus, furunculosis；

Oroxylum indicum, nature and flavor：It is bitter, sweet, cool, there is the effect of removing heat from the lung and relieving sorethroat, soothing liver and harmonizing stomach, for treating cough with lung heat, larynx numbness, sound Mute, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach；

Chinese alpine rush, nature and flavor：It is sweet, light, flat, there is the effect of heat clearing and inflammation relieving, flat liver improving eyesight, hemostasis, for treating flu, hepatitis, small Youngster's pneumonia, mastitis, urticaria, puerperal fever, stomachache, traumatism and bleeding；

The root bark of Chinese wolf-berry, nature and flavor：It is sweet, cold, have heat-clearing, cool blood the effect of, for treat consumptive disease hectic fever night sweat, lung heat cough and asthma, haematemesis, Bleeding from five sense organs or subcutaneous tissue, blood strangury, quench one's thirst, the disease such as hypertension, carbuncle swells, malignant sore；

Pyrrosia lingua, nature and flavor：Sweet, bitter, cold nature, there is the effect of inducing diuresis for treating strangurtia, removing heat from the lung to relieve cough, cooling blood and hemostasis, for treating heat Leaching, blood strangury, urolithiasis, urinary obstruction, leaching drip the diseases such as puckery pain, dyspnea and cough due to lung-heat, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, uterine bleeding；

Citron, nature and flavor：It is pungent, bitter, sour, warm, have in dispersing stagnated hepatoqi, width, clears phlegm, for treating stagnation of liver-QI and stomach-QI, chest side of body The diseases such as distending pain, epigastric abdominal fullness, vomits gas, many coughs of phlegm；

Schizaea digitata (L.) Sw, nature and flavor：It is mildly bitter flavor, cool in nature, there is the effect of clearing heat and detoxicating, for treating cold, fever, abscess of throat；

Bryozoatum, nature and flavor：Taste is salty, cold in nature, nontoxic, has the effect of softening hard masses, treating stranguria, diuresis, clearing lung-heat fire, change old phlegm, for controlling The diseases such as treatment phlegm heat panting is coughed, old phlegm product block, goiter and tumor, scrofula, gonorrhoea, hernia, sore swells, mesh screen；

Wide muscle rattan, nature and flavor：It is bitter, cool in nature, there is the effect of relaxing tendons and activating collaterals, wind-expelling pain-stopping, for treating arthralgia pain due to rheumatism, ischium god The diseases such as dysmenorrhoea, lumbar muscle strain, traumatic injury；

Caulis bambusae in taenian, nature and flavor：Sweet, cold nature, there is the effect of clearing heat and eliminating phlegm, relieving restlessness, preventing or arresting vomiting, for treating phlegm-heat cough, courage fire Hold phlegm under the arm, palpitate with fear not peaceful, vexed insomnia, middle wind phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pernicious vomiting, fetal irritability；

Aster, nature and flavor：Bitter, temperature, has the effect of warm lung, lower gas, dissolving phlegm, cough-relieving, for treating cough due to wind-cold evil's asthma, consumptive disease cough The diseases such as vomiting of pus and blood, larynx numbness, difficult urination；

Hedge Prinsepia Nut, nature and flavor：It is sweet, cold, there is the effect of wind-dispelling, radiating, nourishing the liver, improving eyesight, for treat red eye, swell pain, it is dim it is shy it is cloudy, The rotten more tears of the corner of the eyes, nosebleed epistaxis, also control the diseases such as trusted subordinate's heat symptoms caused by an exopathgen, knot dry phlegm-syndrome ruffian；

Included-in-the-Appendices cream, nature and flavor：It is sweet, mild-natured, there is the effect of moistening the lung and relieve the cough, removing dampness and detoxicating, for treating consumptive lung disease, cough with dyspnea, bald The diseases such as sore, stubborn dermatitis, hemorrhoid, ulcer on the shank；

Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning.

Medicine of the present invention is the principle based on the Chinese traditional treatment early stage of lung cancer, from the pathomechanism and pharmacology according to the early stage of lung cancer Effect is thought：With regard to the early stage of lung cancer, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had very well to above-mentioned disease Therapeutic effect.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of the above-mentioned early stage of lung cancer, prepared using the formula Medicine effect is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific of the present invention Embodiment is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating the early stage of lung cancer, it is characterised in that each component and mass parts ratio of the medicine are as follows It is shown：

Dayflower 280g, sub- clarinet bacterium 120g, cordate houttuynia 220g, Japanese Cayratia Herb 280g, Chinese olive 95g, tendril-leaved fritillary bulb 95g, Ku Zhi 280g, wood Butterfly 31g, Chinese alpine rush 420g, root bark of Chinese wolf-berry 230g, pyrrosia lingua 118g, citron 95g, Schizaea digitata (L.) Sw 120g, bryozoatum 120g, wide muscle rattan 280g, caulis bambusae in taenian 95g, aster 120g, Hedge Prinsepia Nut 120g, Included-in-the-Appendices cream 120g, radix glycyrrhizae 118g, auxiliary material：Appropriate starch.

Embodiment 2：

A kind of capsule medicine for treating the early stage of lung cancer, it is characterised in that each component and mass parts ratio of the medicine are as follows It is shown：

Dayflower 310g, sub- clarinet bacterium 140g, cordate houttuynia 250g, Japanese Cayratia Herb 310g, Chinese olive 105g, tendril-leaved fritillary bulb 105g, Ku Zhi 310g, Oroxylum indicum 35g, Chinese alpine rush 480g, root bark of Chinese wolf-berry 260g, pyrrosia lingua 130g, citron 105g, Schizaea digitata (L.) Sw 140g, bryozoatum 140g, wide muscle rattan 310g, caulis bambusae in taenian 105g, aster 140g, Hedge Prinsepia Nut 140g, Included-in-the-Appendices cream 140g, radix glycyrrhizae 130g, auxiliary material：Appropriate starch.

Embodiment 3：

A kind of capsule medicine for treating the early stage of lung cancer, it is characterised in that each component and mass parts ratio of the medicine are as follows It is shown：

Dayflower 350g, sub- clarinet bacterium 160g, cordate houttuynia 280g, Japanese Cayratia Herb 350g, Chinese olive 120g, tendril-leaved fritillary bulb 120g, Ku Zhi 350g, Oroxylum indicum 40g, Chinese alpine rush 550g, root bark of Chinese wolf-berry 300g, pyrrosia lingua 150g, citron 120g, Schizaea digitata (L.) Sw 160g, bryozoatum 160g, wide muscle rattan 350g, caulis bambusae in taenian 120g, aster 160g, Hedge Prinsepia Nut 160g, Included-in-the-Appendices cream 160g, radix glycyrrhizae 150g, auxiliary material：Appropriate starch.

Model case：

Through clinical conditions early stage of lung cancer patient totally 1260, the age is 730 of more than 68 years old, and only 530 are 68 years old Below.Being fully recovered in 1260 patients and extending life cycle has 280, effective 526, invalid 454.Total effective rate reaches 64%。

Claims (3)

1. A kind of 1. capsule medicine for treating the early stage of lung cancer, it is characterised in that each component and its mass parts ratio of the medicine It is as follows：

   150~350g of dayflower, 100~160g of sub- clarinet bacterium, 150~280g of cordate houttuynia, 150~350g of Japanese Cayratia Herb, Chinese olive 50 ~120g, 150~350g of tendril-leaved fritillary bulb 30~120g, Ku Zhi, 10~40g of Oroxylum indicum, 250~550g of Chinese alpine rush, the root bark of Chinese wolf-berry 150~ 300g, 60~150g of pyrrosia lingua, 30~120g of citron, 60~160g of Schizaea digitata (L.) Sw, 80~160g of bryozoatum, 150~350g of wide muscle rattan, 50~120g of caulis bambusae in taenian, 25~160g of aster, 80~160g of Hedge Prinsepia Nut, 80~160g of Included-in-the-Appendices cream, 30~150g of radix glycyrrhizae, auxiliary material：Starch is fitted Amount.
2. 2. the capsule medicine of the treatment early stage of lung cancer according to claim 1, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：

   180~310g of dayflower, 115~140g of sub- clarinet bacterium, 180~250g of cordate houttuynia, 180~310g of Japanese Cayratia Herb, Chinese olive 58 ~105g, 180~310g of tendril-leaved fritillary bulb 38~105g, Ku Zhi, 12~35g of Oroxylum indicum, 280~480g of Chinese alpine rush, the root bark of Chinese wolf-berry 180~ 260g, 70~130g of pyrrosia lingua, 36~105g of citron, 70~140g of Schizaea digitata (L.) Sw, 90~140g of bryozoatum, 180~310g of wide muscle rattan, 58~105g of caulis bambusae in taenian, 28~140g of aster, 90~140g of Hedge Prinsepia Nut, 90~140g of Included-in-the-Appendices cream, 38~130g of radix glycyrrhizae, auxiliary material：Starch is fitted Amount.
3. 3. the capsule medicine of the treatment early stage of lung cancer according to claim 1 to 2, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

   Dayflower 280g, sub- clarinet bacterium 120g, cordate houttuynia 220g, Japanese Cayratia Herb 280g, Chinese olive 95g, tendril-leaved fritillary bulb 95g, Ku Zhi 280g, wood Butterfly 31g, Chinese alpine rush 420g, root bark of Chinese wolf-berry 230g, pyrrosia lingua 118g, citron 95g, Schizaea digitata (L.) Sw 120g, bryozoatum 120g, wide muscle rattan 280g, caulis bambusae in taenian 95g, aster 120g, Hedge Prinsepia Nut 120g, Included-in-the-Appendices cream 120g, radix glycyrrhizae 118g, auxiliary material：Appropriate starch.