CN107875345A - A kind of Chinese medicine preparation for treating lung cancer and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of Chinese medicine preparation for treating lung cancer according to the understanding mechanism of Chinese traditional treatment lung cancer, each component and its mass parts ratio of the Chinese medicine preparation are as follows：30~45g of the seed of garden balsam, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 30~150g, 30~120g of curcuma zedoary, 15~35g of leech, 30~70g of scorpio, 60~160g of oriental wormwood, 40~80g of centipede, 30~90g of pangolin, 10~40g of asarum, 50~160g of the red sage root, 150~350g of oyster, 90~160g of Snakegourd Fruit, 30~120g of root tuber of aromatic turmeric, 30~120g of ginseng, 60~160g of psoralea corylifolia, 30~45g of Bungarus Parvus, 150~350g of Sculellaria barbata；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of Chinese medicine preparation for treating lung cancer and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine preparation for treating lung cancer, particularly suffer from for lung cancer The field of the Chinese medicine preparation that person uses and preparation method thereof.

Background technology

Doctor thinks：Lung cancer is that morbidity and mortality growth is most fast, and maximum to population health and life threat is pernicious One of tumour.Many countries all report that the morbidity and mortality of lung cancer substantially increase in the past 50 years, the male lung cancer incidence of disease First of all malignant tumours is accounted for the death rate, the women incidence of disease accounts for second, and the death rate accounts for second.The cause of disease of lung cancer So far not completely clearly, great mass of data shows, long-term a large amount of smokings and lung cancer have very close relationship.It is existing Research has shown that：The probability that long-term a large amount of smokers suffer from lung cancer is 10~20 times of non-smoker, and it is smaller to start the age of smoking, suffers from The probability of lung cancer is higher.In addition, smoking not only directly affects my health, the also health generation to surrounding population is bad Influence, cause involuntary smoker's lung cancer illness rate substantially to increase.The incidence of disease of city dweller's lung cancer is higher than rural area, and this may be with city City's atmosphere pollution with flue dust contain carcinogen it is relevant.

So, a kind of Chinese medicine composition that can effectively treat lung cancer how is just found, is that those skilled in the art urgently will Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment lung cancer, people gradually appreciate Chinese traditional treatment lung The advantages of cancer, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment lung cancer Present situation, the purpose of the present invention are to be to provide a kind of Chinese medicine preparation for treating lung cancer, are got well early with solving patients with lung cancer The problem of with life cycle is extended.The medicine be using common Chinese medicine as raw material, can by selecting rational medicine and mass parts ratio Above-mentioned lung cancer one is effectively treated to demonstrate,prove.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of Chinese medicine for treating lung cancer is provided Preparation and preparation method thereof, it is characterised in that each component and mass parts of the Chinese medicine preparation are than as follows：

30~45g of the seed of garden balsam, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 30~150g, 30~120g of curcuma zedoary, 15~35g of leech, scorpio 30~ 70g, 60~160g of oriental wormwood, 40~80g of centipede, 30~90g of pangolin, 10~40g of asarum, 50~160g of the red sage root, oyster 150~ 350g, 90~160g of Snakegourd Fruit, 30~120g of root tuber of aromatic turmeric, 30~120g of ginseng, 60~160g of psoralea corylifolia, 30~45g of Bungarus Parvus, 150~350g of Sculellaria barbata.

A kind of Chinese medicine preparation for treating lung cancer and preparation method thereof, it is characterised in that each component of the Chinese medicine preparation And mass parts are than as follows：

35~42g of the seed of garden balsam, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 38~130g, 38~105g of curcuma zedoary, 18~31g of leech, scorpio 35~ 60g, 70~140g of oriental wormwood, 46~70g of centipede, 38~80g of pangolin, 11~35g of asarum, 58~140g of the red sage root, oyster 180~ 310g, 100~140g of Snakegourd Fruit, 38~105g of root tuber of aromatic turmeric, 38~105g of ginseng, 70~140g of psoralea corylifolia, Bungarus Parvus 38~ 42g, 180~310g of Sculellaria barbata, auxiliary material：Appropriate starch.

A kind of Chinese medicine preparation for treating lung cancer and preparation method thereof, it is characterised in that each component of the Chinese medicine preparation And mass parts are than as follows：

Impetuous 38g, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 118g, curcuma zedoary 95g, leech 26g, scorpio 52g, oriental wormwood 120g, centipede 60g, wear Naze 70g, asarum 32g, red sage root 120g, oyster 280g, Snakegourd Fruit 120g, root tuber of aromatic turmeric 95g, ginseng 95g, psoralea corylifolia 120g, money are white Flower snake 36g, Sculellaria barbata 280g, auxiliary material：Appropriate starch.

A kind of Chinese medicine preparation for treating lung cancer and preparation method thereof, it is characterised in that methods described comprises the following steps to make It is standby to form：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, the raw material Chinese medicine wrapped is put into after soaking 35min in cold boiling water, then soaked medicine is put into marmite and decocted Three times：1. amount of water is 9~10 times of medicinal material total amount, high heat decoction is first carried out, when 15min is arrived in decoction, turns slow fire and boils 115 Min, leaching decoction；2. amount of water is 8~9 times of dry dregs of a decoction total amount, high heat decoction is first carried out, when 10min is arrived in decoction, is turned Slow fire boils 105 min, leaching decoction；3. amount of water is 7~8 times of dry dregs of a decoction total amount, high heat decoction is first carried out, waits to decoct During to 8min, turn slow fire and boil 90 min, leaching decoction；4. merging decoction three times, and it is concentrated under reduced pressure into every milliliter contained 3g Standard after, that is, obtain drug extract.

C, by the extract dry prepared in above-mentioned B, sterilization, and it is standby according to mass parts ratio to be ground into superfine end；

D, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, by superfine myrrh ground in A and C After thing sieving, and auxiliary material is put into medicine device and is well mixed in the lump, is then prepared into capsule（Total length after its capsule is sealed is 23.3mm, medicinal powder capacity 0.4~0.5g/ grains）, then polish, sterilize, sealed packaging produces.

A kind of Chinese medicine preparation for treating lung cancer and preparation method thereof, it is characterised in that the instructions of taking is：It will prepare Capsule medicine three times a day to take, once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, half an hour warm water is sent after meal Clothes.28 days are a course for the treatment of, and 5 courses for the treatment of of taking medicine, symptom gradually mitigates, and extends the life cycle of patient.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

The seed of garden balsam, nature and flavor：It is slight bitter, pungent, warm, it is slightly poisonous, there is the effect of blood-breaking softening hard masses, disperse accumulations, Yong is in Zhi Liao abdominal lump of mass in abdomen, warp The disease such as close, be dysphagic；

Prepared RADIX ET RHIZOMA RHEI (wine stir-fry), nature and flavor：It is bitter, cold in nature, there is the effect of attacking stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis, removing toxic substances, use In treatment real heat constipation, the thermojunction feeling of stuffiness in chest, damp-heat dysentery, jaundice, gonorrhoea, oedema abdomen be full, difficult urination, hot eyes, abscess of throat, Aphthae, gastropyretic vomiting, haematemesis, spitting of blood, bleeding from five sense organs or subcutaneous tissue, have blood in stool, hematuria, store blood, Amenorrhea, postpartum stasis of blood, lumps in the chest and abdomen, fall Beat the diseases such as damage, heat toxin large carbuncle, erysipelas, scald；

Curcuma zedoary, nature and flavor：It is acrid flavour, hardship, warm-natured, there is the effect of promoting the circulation of qi blood-breaking, Xiao Ji Zhi Tong, vim and vigour are pained, diet for treating Stagnant, abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury；

Leech, nature and flavor：It is salty, bitter, flat, have blood-breaking stimulate the menstrual flow, by stagnation resolvation disease the effect of, for treat blood stasis, addiction lump in the abdomen lump in the abdomen, Hemiplegia, injury from falling down；

Scorpio, nature and flavor：It is pungent, flat, have ceases wind antispastic, remove obstruction in channels to relieve pain, dispersing pathogen accumulation the effect of, for treating liver wind agitation, convulsion The diseases such as contraction twitch, child convulsion, middle air port, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula；

Oriental wormwood, nature and flavor：Bitter, pungent, cold nature, there are eliminating dampness and heat, normalizing gallbladder to cure jaundice, for treating jaundice urine Less, the disease such as damp-warm syndrome summer-heat and damp, wet sore itch；

Centipede, nature and flavor：It is pungent, warm, it is poisonous, have ceases wind antispastic, remove obstruction in channels to relieve pain, dispersing pathogen accumulation the effect of, for treating in liver wind Dynamic, spasm twitch, child convulsion, middle air port fish sticking its mouth out of the water, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula, snake Insect bite；

Pangolin, nature and flavor：It is salty, cool, big poison, there is blood circulation promoting and dispersing pathogen accumulation, stimulate the menstrual flow lower breast, anti-stain in solid the effect of, for treating blood stasis Amenorrhea, abdominal mass, arthralgia pain due to rheumatism, agalactia, carbuncle swells, scrofula, for Jing Bi wei lump in the abdomen, alactation, carbuncle sore tumefacting virus, joint numbness Bitterly, the disease such as numbness contracture；

Asarum, nature and flavor：It is pungent, warm, there is the effect of expelling wind and clearing away cold, sensible analgesic, Wenfei of drink, for treating anemofrigid cold, head Bitterly, have a toothache, have a stuffy nose nasosinusitis, arthralgia pain due to rheumatism, sputum cough；

The red sage root, nature and flavor：Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Oyster, nature and flavor：Taste is salty, cold nature, has the effect of calming the liver, transquilization with heavy material, softening and resolving hard mass, convergence is astringent or styptic treatment for spontaneous sweating, is used for Treat dizziness and tinnitus, insomnia of palpitating with fear, scrofula goiter and tumor, abdominal mass lump in the abdomen, spontaneous sweating, seminal emission, uterine bleeding, with inferior disease；

Snakegourd Fruit, nature and flavor：It is sweet, bitter, cold, there is the effect of clearing lung-heat, resolving sputum, relieving stuffiness of the chest by dispersing aggregation of pathogens, ease constipation, for treating the hot cough and asthma of phlegm, lung The diseases such as carbuncle, the obstruction of qi in the chest, accumulation of pathogens in chest, acute mastitis swell and ache, quenched one's thirst, jaundice, constipation；

Root tuber of aromatic turmeric, nature and flavor：It is pungent, bitter, cold, there is the effect of promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, normalizing gallbladder to cure jaundice, for treating For chest side of body shouting pain, chest impediment and cardialgia, closed dysmenorrhea, swollen breasts, pyreticosis coma, epilepsy go mad, blood-head tells nosebleed, jaundice；

Ginseng, nature and flavor：Mild-natured, sweet, slight bitter, have and reinforce vital energy, veins takes off admittedly, reinforce the spleen to benefit the lung, promote the production of body fluid to quench thirst, tranquilize the mind and promote the intelligence The effect of, for treat deficient internal lesion caused by overexertion, deficiency of food, burnout, regurgitation and emesis, stool lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, be good for Forget, dizziness and headache, impotence, frequent micturition, quench one's thirst, woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, the card of all qi-blood-body fluid deficiencies；

Psoralea corylifolia, nature and flavor：It is acrid flavour, hardship, warm-natured, there is the effect of tonifying the kidney and support yang, gas of receiving is relievingd asthma, is warming spleen and stopping diarrha, for treating kidney It is long that YANG deficiency, below element deficiency and cold, waist and knee crymodynia, impotence essence, frequent micturition, the enuresis, the failure of the kidney in receiving air, void breathe heavily more than, speen-kidney dificiency, stool Rush down, the disease such as leucoderma, alopecia areata, psoriasis；

Bungarus Parvus, nature and flavor：It is sweet, salty, warm-natured, it is poisonous, there is the effect of dispelling wind and removing obstruction in the meridians, arresting convulsion stop convulsion, for treating wind The disease such as arthritis with fixed pain caused by dampness pain, spasm of muscles and vessels, middle air port eye, oblique, hemiplegia, child convulsion, lockjaw, leprosy, mange, syphilis, malignant sore；

Sculellaria barbata, nature and flavor：It is acrid flavour, hardship, cold in nature, there is the effect of clearing heat and detoxicating, stagnation resolvation diuresis, for treating furuncle swelling toxin, pharynx The diseases such as larynx swelling and pain, the pain of injury caused by falling and tumbling, oedema, jaundice, snake bite and insect sting.

Medicine of the present invention is the principle based on Chinese traditional treatment lung cancer, is recognized from the pathomechanism according to lung cancer and pharmacological action For：With regard to lung cancer, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned lung cancer, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of Chinese medicine preparation for treating lung cancer, it is characterised in that each component and mass parts of the Chinese medicine preparation are than following institute Show：

Impetuous 38g, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 118g, curcuma zedoary 95g, leech 26g, scorpio 52g, oriental wormwood 120g, centipede 60g, wear Naze 70g, asarum 32g, red sage root 120g, oyster 280g, Snakegourd Fruit 120g, root tuber of aromatic turmeric 95g, ginseng 95g, psoralea corylifolia 120g, money are white Flower snake 36g, Sculellaria barbata 280g, auxiliary material：Appropriate starch.

Embodiment 2：

A kind of Chinese medicine preparation for treating lung cancer, it is characterised in that each component and mass parts of the Chinese medicine preparation are than following institute Show：

Impetuous 42g, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 130g, curcuma zedoary 105g, leech 31g, scorpio 60g, oriental wormwood 140g, centipede 70g, wear Naze 80g, asarum 35g, red sage root 140g, oyster 310g, Snakegourd Fruit 140g, root tuber of aromatic turmeric 105g, ginseng 105g, psoralea corylifolia 140g, money Long-noded pit viper 42g, Sculellaria barbata 310g, auxiliary material：Appropriate starch.

Embodiment 3：

A kind of Chinese medicine preparation for treating lung cancer, it is characterised in that each component and mass parts of the Chinese medicine preparation are than following institute Show：

Impetuous 45g, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 150g, curcuma zedoary 120g, leech 35g, scorpio 70g, oriental wormwood 160g, centipede 80g, wear Naze 90g, asarum 40g, red sage root 160g, oyster 350g, Snakegourd Fruit 160g, root tuber of aromatic turmeric 120g, ginseng 120g, psoralea corylifolia 160g, money Long-noded pit viper 45g, Sculellaria barbata 350g.

Model case：

Through clinical conditions patients with lung cancer totally 1298, the age is 746 of more than 66 years old, and only 552 are less than 66 years old. Extend life cycle in 1298 patients has 380, effective 736, invalid 182.Total effective rate is up to 86%.

Claims (3)

1. a kind of Chinese medicine preparation for treating lung cancer, it is characterised in that each component and its mass parts of the Chinese medicine preparation are such as Shown in lower：

30~45g of the seed of garden balsam, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 30~150g, 30~120g of curcuma zedoary, 15~35g of leech, scorpio 30~ 70g, 60~160g of oriental wormwood, 40~80g of centipede, 30~90g of pangolin, 10~40g of asarum, 50~160g of the red sage root, oyster 150~ 350g, 90~160g of Snakegourd Fruit, 30~120g of root tuber of aromatic turmeric, 30~120g of ginseng, 60~160g of psoralea corylifolia, 30~45g of Bungarus Parvus, 150~350g of Sculellaria barbata.

2. the Chinese medicine preparation for the treatment of lung cancer according to claim 1, it is characterised in that each component of the Chinese medicine preparation And its mass parts are than as follows：

35~42g of the seed of garden balsam, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 38~130g, 38~105g of curcuma zedoary, 18~31g of leech, scorpio 35~ 60g, 70~140g of oriental wormwood, 46~70g of centipede, 38~80g of pangolin, 11~35g of asarum, 58~140g of the red sage root, oyster 180~ 310g, 100~140g of Snakegourd Fruit, 38~105g of root tuber of aromatic turmeric, 38~105g of ginseng, 70~140g of psoralea corylifolia, Bungarus Parvus 38~ 42g, 180~310g of Sculellaria barbata, auxiliary material：Appropriate starch.

3. the Chinese medicine preparation of the treatment lung cancer according to claim 1 to 2, it is characterised in that the Chinese medicine preparation it is each Component and its mass parts are than as follows：

Impetuous 38g, prepared RADIX ET RHIZOMA RHEI (wine stir-fry) 118g, curcuma zedoary 95g, leech 26g, scorpio 52g, oriental wormwood 120g, centipede 60g, wear Naze 70g, asarum 32g, red sage root 120g, oyster 280g, Snakegourd Fruit 120g, root tuber of aromatic turmeric 95g, ginseng 95g, psoralea corylifolia 120g, money are white Flower snake 36g, Sculellaria barbata 280g, auxiliary material：Appropriate starch.