CN107823522A - A kind of pill medicine for treating epigastric pain and preparation method thereof - Google Patents

A kind of pill medicine for treating epigastric pain and preparation method thereof Download PDF

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Publication number
CN107823522A
CN107823522A CN201711037361.3A CN201711037361A CN107823522A CN 107823522 A CN107823522 A CN 107823522A CN 201711037361 A CN201711037361 A CN 201711037361A CN 107823522 A CN107823522 A CN 107823522A
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medicine
epigastric pain
pain
mass parts
galangal
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夏瑜
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Sichuan Jintang Haina Biomedical Technology Institute
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Sichuan Jintang Haina Biomedical Technology Institute
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/235—Foeniculum (fennel)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739—Sanguisorba (burnet)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of pill medicine for treating epigastric pain according to the understanding mechanism of Chinese traditional treatment epigastric pain, each component and its mass parts ratio of the medicine are as follows：30~80g of the coptis, 100~160g of sealwort, 30~120g of radix bupleuri, 30~120g of the banksia rose, 50~150g of the root of herbaceous peony, 30~120g of Buddha's hand, 30~70g of galangal, 30~70g of fennel seeds, 60~160g of garden burnet, 60~160g of bletilla, 30~120g of radix glycyrrhizae, 30~120g of the membrane of a chicken's gizzard, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of pill medicine for treating epigastric pain and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating epigastric pain, particularly for gastral cavilty The field of the pill medicine that pain patient uses and preparation method thereof.
Background technology
Doctor thinks：Stomachache category Chinese medical disease name.More by diseases caused by external factors cold-evil, injury due to diet, feelings will is not smooth and emptiness of spleen and stomach etc. The cause of disease and trigger.Stomach is major lesions internal organs, often with liver and spleen etc. is dirty substantial connection.Stagnation of stomach-QI, lose in drop be stomachache Main pathogenesis.Treatment, according to different syndromes, takes corresponding therapy using regulating qi-flowing for harmonizing stomach as big method.
So, just how to find a kind of Chinese medicine composition that can effectively treat epigastric pain, be those skilled in the art urgently Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment epigastric pain, people gradually appreciate Chinese traditional treatment The advantages of epigastric pain, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment stomach The present situation of gastral cavity pain, the purpose of the present invention are to be to provide a kind of pill medicine for treating epigastric pain, to solve epigastric pain patient morning The problem of day gets well.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can be had Effect treats above-mentioned epigastric pain.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of ball for treating epigastric pain is provided Agent medicine and preparation method thereof, it is characterised in that each component and mass parts of the medicine are than as follows：
30~80g of the coptis, 100~160g of sealwort, 30~120g of radix bupleuri, 30~120g of the banksia rose, 50~150g of the root of herbaceous peony, Buddha's hand 30~ 120g, 30~70g of galangal, 30~70g of fennel seeds, 60~160g of garden burnet, 60~160g of bletilla, 30~120g of radix glycyrrhizae, in chicken 30~120g of gold, auxiliary material：Appropriate starch.
A kind of pill medicine for treating epigastric pain and preparation method thereof, it is characterised in that each component of the medicine and Mass parts are than as follows：
38~70g of the coptis, 115~140g of sealwort, 38~105g of radix bupleuri, 38~105g of the banksia rose, 58~130g of the root of herbaceous peony, Buddha's hand 38~ 105g, 38~60g of galangal, 38~60g of fennel seeds, 70~140g of garden burnet, 70~140g of bletilla, 38~105g of radix glycyrrhizae, in chicken 38~105g of gold, auxiliary material：Appropriate starch.
A kind of pill medicine for treating epigastric pain and preparation method thereof, it is characterised in that each component of the medicine and Mass parts are than as follows：
Coptis 60g, sealwort 120g, radix bupleuri 95g, banksia rose 95g, root of herbaceous peony 115g, Buddha's hand 95g, galangal 52g, fennel seeds 52g, Elm 120g, bletilla 120g, radix glycyrrhizae 95g, the membrane of a chicken's gizzard 95g, auxiliary material：Appropriate starch.
A kind of pill medicine for treating epigastric pain and preparation method thereof, it is characterised in that each component of the medicine and Mass parts are than as follows：
A, in addition to auxiliary material, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With；
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, is then prepared into the water-bindered pill（The granularity of its water-bindered pill is：3.8mm~4.0mm）, and then dry, sealed packaging.
A kind of pill medicine for treating epigastric pain and preparation method thereof, it is characterised in that the instructions of taking is：It will prepare Good water pill medicine is twice a day to take, and once a dose sooner or later, dosage 6g/ times, warm water delivery service, and 7 days are a treatment Journey, 1~3 course for the treatment of of taking medicine, symptom disappear, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has in detail in Chinese Pharmacopoeia, Chinese medicine voluminous dictionary and China's book on Chinese herbal medicine Thin record.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：
The coptis, nature and flavor：Cold in nature, bitter, there is the effect of purging intense heat, eliminating dampness, removing toxic substances, desinsection, row heat toxin during for treating, typhoid fever, Inverse, bacillary dysentery that excess heat is vexed, feeling of fullness is vomitted, heat rush down stomachache, lung knot by, tell, be defeated in battle, lower blood, quench one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, roundworm disease, pertussis, pharynx Larynx swelling and pain, pinkeye, aphtha, skin sore, eczema, the burning hot wound of soup；
Sealwort, nature and flavor：It is sweet, flat, have Yin nourishing and lung moistening, invigorate the spleen and benefit qi, Zishen fill fine the effect of, for treating deficiency of Yin overstrain cough, lung Cough caused by dryness is coughed, insufficiency of the spleen weak, few dry of food, quench one's thirst, deficiency of the kidney soreness and weakness of waist and knees, impotence and seminal emission, tinnitus mesh are dark, poliosis, physically weak win Thin, wind favus disease；
Radix bupleuri, nature and flavor：It is bitter, be slightly cold, have and inducing diaphoresis in, soothing the liver, rising Yang the effect of, for treat cold, fever, fevers and chills alternate, The diseases such as distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, prolapse of the anus；
The banksia rose, nature and flavor：It is pungent acrid flavour, hardship, warm-natured, there is promoting qi circulation and relieving pain, adjust in lead the effect of stagnant, for treat born of the same parents coerce turgor foot, Weight after abdominal distention, vomiting and having loose bowel, dysentery；
The root of herbaceous peony, nature and flavor：Bitter, acid, it is slightly cold, there is blood-nourishing and battalion, relieving spasm to stop pain, hold back the effect of high and level tone liver, for treating menstruation not The diseases such as tune, dysmenorrhea, uterine bleeding, spontaneous perspiration, night sweat, side of body rib epigastric pain, four limbs contraction pain, headache, dizziness；
Buddha's hand, nature and flavor：It is acrid flavour, hardship, acid, warm-natured, there is the effect of dispersing stagnated hepatoqi and helmet analgesic, eliminating dampness and eliminating phlegm, for treating liver Stomach Qi is stagnant, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food are vomitted, coughing with a lot of sputum；
Galangal, nature and flavor：It is pungent, warm, there is the effect of warm stomach, wind-dispelling, cold dispelling, promoting the circulation of qi, analgesic, for treating taste syncope due to pathogenic cold, gastral cavity The diseases such as abdomen crymodynia, vomiting and diarrhea, the gastric disorder causing nausea of choke dried meat, food stagnation, malignant malaria, cold addiction；
Fennel seeds, nature and flavor：It is acrid flavour, warm-natured, there is the effect of warm kidney warms up liver, promoting qi circulation and relieving pain and stomach, for treat cold hernia stomachache, The diseases such as the testis swelling and hanging down of either of the testes, coldness and pain in the epigastrium, deficiency of food vomiting and diarrhoea, hypochondriac pain, lumbago due to the kidney deficiency, dysmenorrhoea；
Garden burnet, nature and flavor：It is picric acid, cold, it is nontoxic, there is the effect of cooling blood and hemostasis, clearing heat and detoxicating, healing up sore and subduing swelling, for treat spit blood, Spitting of blood, bleeding from five sense organs or subcutaneous tissue, hematuria, have blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, leukorrhea with reddish discharge, sore, carbuncle and painful swelling, eczema, pruritus vulvae, scald, snakeworm Bite；
Bletilla, nature and flavor：It is bitter, sweet, puckery, be slightly cold, have astringing to arrest bleeding, detumescence and promoting granulation the effect of, for treat hemoptysis spit blood, wound Bleeding, sore swollen toxin, chapped skin, pulmonary tuberculosis hemoptysis, ulcer haemorrhage；
Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning；
The membrane of a chicken's gizzard, nature and flavor：It is sweet, flat, have stomach strengthening and digestion promoting, arresting seminal emission the effect of, for treat dyspepsia, vomiting dysentery, The diseases such as infantile malnutrition, the enuresis, seminal emission.
Medicine of the present invention is the principle based on Chinese traditional treatment epigastric pain, from the pathomechanism according to epigastric pain and pharmacological action Think：With regard to epigastric pain, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good effect to above-mentioned disease Fruit.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned epigastric pain, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific reality of the present invention The mode of applying is described in further detail：
Embodiment 1：
A kind of pill medicine for treating epigastric pain, it is characterised in that each component and mass parts of the medicine are than as follows：
Coptis 60g, sealwort 120g, radix bupleuri 95g, banksia rose 95g, root of herbaceous peony 115g, Buddha's hand 95g, galangal 52g, fennel seeds 52g, Elm 120g, bletilla 120g, radix glycyrrhizae 95g, the membrane of a chicken's gizzard 95g, auxiliary material：Appropriate starch.
Embodiment 2：
A kind of pill medicine for treating epigastric pain, it is characterised in that each component and mass parts of the medicine are than as follows：
Coptis 70g, sealwort 140g, radix bupleuri 105g, banksia rose 105g, root of herbaceous peony 130g, Buddha's hand 105g, galangal 60g, fennel seeds 60g, Garden burnet 140g, bletilla 140g, radix glycyrrhizae 105g, the membrane of a chicken's gizzard 105g, auxiliary material：Appropriate starch.
Embodiment 3：
A kind of pill medicine for treating epigastric pain, it is characterised in that each component and mass parts of the medicine are than as follows：
Coptis 80g, sealwort 160g, radix bupleuri 120g, banksia rose 120g, root of herbaceous peony 150g, Buddha's hand 120g, galangal 70g, fennel seeds 70g, Garden burnet 160g, bletilla 160g, radix glycyrrhizae 120g, the membrane of a chicken's gizzard 120g, auxiliary material：Appropriate starch.
Model case
Through clinical conditions epigastric pain patient totally 1530, the age is 865 of more than 49 years old, only 665 for 49 years old with Under.875 to be fully recovered in 1530 patients, effective 533, invalid 122.Total effective rate is up to 92%.

Claims (3)

1. a kind of pill medicine for treating epigastric pain, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：
30~80g of the coptis, 100~160g of sealwort, 30~120g of radix bupleuri, 30~120g of the banksia rose, 50~150g of the root of herbaceous peony, Buddha's hand 30~ 120g, 30~70g of galangal, 30~70g of fennel seeds, 60~160g of garden burnet, 60~160g of bletilla, 30~120g of radix glycyrrhizae, in chicken 30~120g of gold, auxiliary material：Appropriate starch.
2. it is according to claim 1 treatment epigastric pain pill medicine, it is characterised in that each component of the medicine and Its mass parts is than as follows：
38~70g of the coptis, 115~140g of sealwort, 38~105g of radix bupleuri, 38~105g of the banksia rose, 58~130g of the root of herbaceous peony, Buddha's hand 38~ 105g, 38~60g of galangal, 38~60g of fennel seeds, 70~140g of garden burnet, 70~140g of bletilla, 38~105g of radix glycyrrhizae, in chicken 38~105g of gold, auxiliary material：Appropriate starch.
3. the pill medicine of the treatment epigastric pain according to claim 1 to 2, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：
Coptis 60g, sealwort 120g, radix bupleuri 95g, banksia rose 95g, root of herbaceous peony 115g, Buddha's hand 95g, galangal 52g, fennel seeds 52g, Elm 120g, bletilla 120g, radix glycyrrhizae 95g, the membrane of a chicken's gizzard 95g, auxiliary material：Appropriate starch.
CN201711037361.3A 2017-10-30 2017-10-30 A kind of pill medicine for treating epigastric pain and preparation method thereof Withdrawn CN107823522A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111840489A (en) * 2020-07-06 2020-10-30 青先永 A Chinese medicinal composition for treating gastric erosion, polyp, ulcer, and proctitis, and its preparation method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111840489A (en) * 2020-07-06 2020-10-30 青先永 A Chinese medicinal composition for treating gastric erosion, polyp, ulcer, and proctitis, and its preparation method

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Application publication date: 20180323