CN107582831A - It is a kind of effectively to alleviate gaseous distention and the Chinese medicine composition of hiccup - Google Patents
It is a kind of effectively to alleviate gaseous distention and the Chinese medicine composition of hiccup Download PDFInfo
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- CN107582831A CN107582831A CN201710756364.6A CN201710756364A CN107582831A CN 107582831 A CN107582831 A CN 107582831A CN 201710756364 A CN201710756364 A CN 201710756364A CN 107582831 A CN107582831 A CN 107582831A
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Abstract
The present invention discloses a kind of effectively alleviation gaseous distention and the Chinese medicine composition of hiccup, and the Chinese medicine composition according to the traditional Chinese medicine of lower parts by weight by forming：15 20 parts of Radix Codonopsis, 15 20 parts of the bighead atractylodes rhizome, 10 20 parts of rhizoma zingiberis, 10 20 parts of rhizoma cyperi, 35 parts of root tuber of aromatic turmeric, 5 15 parts of fennel seeds, 8 15 parts of excrementum pteropi, 3 10 parts of rough gentian, 15 20 parts of ergcibe obtusifolia.The present invention is based on the understanding and principle of reatment to gasteremphraxis symptom mechanism, using the treatment gasteremphraxis Chinese medicine composition of above-mentioned formula, using directly oral method, altogether the effect of long memorial liver and qi, strengthening the spleen and stomach, warming spleen and stomach for dispelling cold, promoting the circulation of qi dissipate-swelling, the treatment to gasteremphraxis, which reaches, treats both principal and secondary aspect of disease；Prescription of the present invention prepares simplicity, medicine source is wide, cost is low.
Description
Technical field
The invention belongs to tcm field, in particular to a kind of effectively alleviation gaseous distention and the Chinese medicine composition of hiccup.
Background technology
The reason for gasteremphraxis, mainly includes：1st, diet is unhygienic；2nd, amount of drinking water is very little or roughage input is made very little
Into constipation flatulence；3rd, daily life system is abnormal.It is also possible at regular time and quantity, cause enteron aisle excessively hungry or be excessively satiated with food, cause
Enteron aisle remarkable action, can making stomach and intestine for a long time, over-burden；That the 4th, eats is too greasy, causes enteron aisle nondigestible；5th, eat too
It hurry up.Chewing can be made not in place, cause digestive juice and food to be thoroughly mixed, thus sufficiently digestion point can not be carried out
Solution, is damaged to enteron aisle；6th, the excessive physiological function that directly affects of pressure is exactly function of intestinal canal exception.Such as hyperhydrochloria, slow down
Wriggling accelerates wriggling etc..Hyperhydrochloria can damage gastric mucosa, and accelerating wriggling can cause to suffer from diarrhoea again and again, and slowing down wriggling can cause
Abdominal distension；7th, disease causes：Clinically superficial gastritis, duodenal ulcer, acute gastritis etc., all based on gasteremphraxis.
The traditional Chinese medical science thinks stomach receiving food and drink, the diastole of stomach and spasm, completes the digestion of food.Conversely, gastric diastole is lacked of proper care with spasm,
Expansion is more than spasm, and gasteremphraxis is into.Why dilatation of the stomach is without spasm, and internal organs hurt is basis.
The method for the treatment of gasteremphraxis includes at present：Ease off the pressure, keep sufficient sleep, frequent defaecation etc., but these methods exist
It can not be taken effect in short time, it is necessary to which long-term adjustment could eliminate gasteremphraxis, and can not effect a radical cure.Although the Western medicine sold on the market takes effect
It hurry up, but be unable to reach the function of regulation stomach, be equally unable to reach the purpose of radical cure gasteremphraxis.
The content of the invention
The purpose of the present invention is the defects of overcoming conventional medicament, there is provided a kind of evident in efficacy, quality is easily controlled, stability
The good Chinese medicine composition for being used to treat gasteremphraxis.
The present invention is achieved through the following technical solutions：A kind of effectively alleviation gaseous distention and the Chinese medicine composition of hiccup, it is described
Chinese medicine composition according to the traditional Chinese medicine of lower parts by weight by forming：Inula britannica chinensis 10-20 parts, excrementum pteropi 10-30 parts, tuber of dwarf lilyturf 35-50
Part, Chinese Fevervine Herb 40-60 parts, radix bupleuri 40-60 parts, dried immature fruit of citron orange 35-50 parts, rough gentian 5-8 parts, lycopodium calvatum 35-50 parts；
A kind of bulk drug pharmacology for effectively alleviating gaseous distention and the Chinese medicine composition of hiccup of the present invention：
Inula britannica chinensis：Slightly warm in nature is bitter, pungent, salty.Return lung warp, stomach.Sending down abnormally ascending, dissolving phlegm, water-filling, preventing or arresting vomiting.Belong to expectorants, antitussives and anti-asthmatics medicine
The medicine for warming and resolving cold-phlegm of lower classification.
Excrementum pteropi：Warm-natured, taste is salty, sweet.Return liver warp.
Cure mainly：Promoting blood circulation and stopping pain, removing blood stasis and hemostasis, disperse accumulations removing toxic substances.Belong to the blood-activating analgesic of drug for invigorating blood circulation and eliminating stasis subordinate classification.
The dried immature fruit of citron orange：Cold nature is bitter, pungent, sour.Returns spleen warp, stomach.Relieving stagnant Qi disperse accumulations, resolving sputum dissipate ruffian.Belong to qi-regulating drug.
The tuber of dwarf lilyturf：Cold nature, sweet, slight bitter.Thoughts of returning home warp, lung channel, stomach.Nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire.Belong to lower point of qi-restoratives medicine
The yin tonics of class.
Radix bupleuri：Cold nature, bitter.Return liver warp, gallbladder channel, lung channel.With in inducing diaphoresis, soothing the liver, rising Yang.Belong to diaphoretic medicine subordinate classification
Cold-pungent and diaphoretic drugs.
Rough gentian：It is cold in nature, bitter.Return liver warp, gallbladder channel.Clearing away the liver-fire, except damp and hot, stomach invigorating.The heat-clearing classified under category antipyretic is rushed down
Gunpowder.
Lycopodium calvatum：It is warm-natured, it is mildly bitter flavor, pungent.Return liver warp, the spleen channel, kidney channel.Cold-dispelling, dehumidification swelling, relaxing tendons and activating collaterals.Category is dispelled
The wind-damp dispelling strengthening the bones and muscles medicine classified under medicine for rheumatism.
To optimize the effect of drugs of medicine, further determine that, 16 parts of Inula britannica chinensis, 20 parts of excrementum pteropi, 50 parts of the tuber of dwarf lilyturf, Chinese Fevervine Herb
40 parts, 40 parts of radix bupleuri, 35 parts of the dried immature fruit of citron orange, 5 parts of rough gentian, 40 parts of lycopodium calvatum.
To optimize the effect of drugs of medicine, further determine that, 10 parts of Inula britannica chinensis, 15 parts of excrementum pteropi, 45 parts of the tuber of dwarf lilyturf, Chinese Fevervine Herb
40 parts, 50 parts of radix bupleuri, 35 parts of the dried immature fruit of citron orange, 6 parts of rough gentian, 40 parts of lycopodium calvatum.
To optimize the effect of drugs of medicine, further determine that, the Chinese medicine composition can be prepared into pharmaceutically acceptable
Formulation.
For optimize medicine effect of drugs, further determine that, pharmaceutically acceptable formulation be selected from decoction, pill, pulvis,
Capsule, tablet or electuary.
The present invention compared with prior art, has the advantage that and had the beneficial effect that：
The present invention is based on the understanding and principle of reatment to gasteremphraxis symptom mechanism, obtained by being prepared using above-mentioned formula and method
Treatment gasteremphraxis Chinese medicine composition, mutual assistant is being used through dialectical compatibility using directly oral method, its drug component
Help, altogether the effect of long memorial liver and qi, strengthening the spleen and stomach, warming spleen and stomach for dispelling cold, promoting the circulation of qi dissipate-swelling, the treatment to gasteremphraxis, which reaches, treats both principal and secondary aspect of disease；This
Invention prescription prepares simplicity, medicine source is wide, cost is low.
Embodiment
The present invention is described in further detail with reference to embodiment, but the implementation of the present invention is not limited to this,
Without departing from the idea case in the present invention described above, according to ordinary skill knowledge and customary means, various replace is made
Change and change, all should be included within the scope of the invention.
Embodiment 1：
It is used for the Chinese medicine composition for treating gasteremphraxis described in the present embodiment, the Chinese medicine composition according to the Chinese medicine of lower parts by weight by matching somebody with somebody
System forms：Inula britannica chinensis 10-20 parts, excrementum pteropi 10-30 parts, tuber of dwarf lilyturf 35-50 part, Chinese Fevervine Herb 40-60 parts, radix bupleuri 40-60 parts, the dried immature fruit of citron orange
35-50 parts, rough gentian 5-8 parts, lycopodium calvatum 35-50 parts；
The preparation method of medicine of the present invention, comprises the following steps：
（1）By above-mentioned whole Chinese medicine material medicines, to be soaked 30 minutes with clear water or pure water in advance, water consumption for immersion is 0.8 ~
1.0L；
（2）Chinese medicine material medicine after immersion and its liquid medicine of immersion are added in decocting container, capping decocts jointly；
（3）Decocting container herb liquid is seethed with excitement with high heat, reuse slow fire and boil 10-15 minutes, 2 ~ 3 need to be stirred when boiling medicine
It is secondary；
（4）After the completion of decoction, add proper amount of clear water or pure water not to have medicine, carry out second and decoct, decoct duration and degree of heating method and be same as above,
Decocting time 5-10 minutes；
（5）Decoction is filtered out, it is endo-medicine to obtain decoction.
Above-mentioned decocting container is marmite, enamel ware or stainless steel, avoids and uses ironware.
The application method of medicine of the present invention：It is directly for oral administration.
Embodiment 2：
The medicine of gasteremphraxis is treated described in the present embodiment, is represented with parts by weight, the Chinese medicine composition is by according in lower parts by weight
Medicine is formulated：16 parts of Inula britannica chinensis, 20 parts of excrementum pteropi, 50 parts of the tuber of dwarf lilyturf, 40 parts of Chinese Fevervine Herb, 40 parts of radix bupleuri, 35 parts of the dried immature fruit of citron orange, rough gentian 5
Part, 40 parts of lycopodium calvatum.
Embodiment 3：
The medicine of gasteremphraxis is treated described in the present embodiment, is represented with parts by weight, the Chinese medicine composition is by according in lower parts by weight
Medicine is formulated：10 parts of Inula britannica chinensis, 15 parts of excrementum pteropi, 45 parts of the tuber of dwarf lilyturf, 40 parts of Chinese Fevervine Herb, 50 parts of radix bupleuri, 35 parts of the dried immature fruit of citron orange, rough gentian 6
Part, 40 parts of lycopodium calvatum.
Embodiment 4：
The medicine of gasteremphraxis is treated described in the present embodiment, the Chinese medicine composition can be prepared into pharmaceutically acceptable formulation；Pharmacy
Acceptable formulation is selected from decoction, pill, pulvis, capsule, tablet or electuary.
Toxicology test：
Acute toxicity test：
Experimental observation, because LD50 can not be measured, therefore the measure of maximum dosage-feeding is carried out.Chinese medicine compound prescription prepared by embodiment 1
Mixture is dissolved in sterile saline, is configured to solution gavage mouse, is as a result shown, is given birth to medicine maximum administration concentration 9.65
Medicine/ml, for maximum administered volume 50ml/kg in being administered twice in 24 hours to mouse stomach, mouse maximum dosage-feeding is 763.25g
Crude drug/kg, animal do not occur adverse reaction and death, each internal organs no abnormality seen of anatomic observation.
Long term toxicity test
SD rats 80 are applied in this experiment, and Chinese medicine compound prescription mixture prepared by embodiment 1 is dissolved in sterile saline, configuration
Into solution gavage, if control group and 24g, 35g, 49g crude drug/kg dosage groups, continuous gavage is administered 12 weeks, observes in the present invention
Influence of the drug composition to animal indices.Result of the test shows that successive administration 12 weeks, Chinese medicine composition of the invention is to big
The body weight of mouse, food ration, peripheral hemogram, clotting time, electrocardiogram, organ index etc. have no significant effect；Blood biochemical 12
Item index determining result, 12 weeks low dose group BiLi values of administration are higher than control group（P<0.05)；Low dose group, middle dose group TP values
Higher than control group（P<0.05), but within normal physiologic range, other indexs no significant difference compared with control group.Recover
Phase each administration group indices measured value and the more equal no significant difference of control group.Each internal organs gross examination of skeletal muscle no abnormality seen of each group.
The clinical statisticses data of various gasteremphraxis patients is directed to using medicine of the present invention：
By the Clinical practice of 200 patients, wherein male patient 127, female patient 73, medication age object 20 ~ 70 years old.Wherein
It is minimum 21 years old, it is maximum 68 years old；Slight gasteremphraxis disease 42, moderate gasteremphraxis disease 72, severe gasteremphraxis disease 36.
Model case：
Case 1, Lee, female, 21 years old, Tianjin people from Hedong District.Patient suffers from aerogastria, takes a variety of drug therapies, has no any
Take a turn for the better, introduced through friend, it is to our hospital, Chinese medicine preparation treatment of the present invention is given, after taking 1 course for the treatment of, symptom has been alleviated,
Continue after taking 2 courses for the treatment of, symptom is disappeared, and recovery from illness, follow-up is not recurred so far.
Case 2, Chen, man, 35 years old, Shanghai people from Yangpu District.Patient's gastral cavilty ruffian, nausea and vomiting, lassitude, abdominal distension, big loose stool,
Urine is yellow, and with heating, red tongue with yellowish fur, deeptensepulse number, has stomach trouble history in the past 2 years, used multi-medicament treatment, poor effect,
It is invalid to cure, rear to our hospital, takes Chinese medicine preparation treatment of the present invention, and after taking 1 course for the treatment of, symptom has taken a turn for the better, and continues
After taking 2 courses for the treatment of, symptom is disappeared, and recovery from illness, follow-up is not recurred so far.
Case 3, poplar, female, 44 years old, Chongqing people from Wansheng District.Patient is cold, fatiguability, often has a dizzy spell, and appetite is not
Good, gynecological ailments is rear to our hospital, is diagnosed as aerogastria, after take Chinese medicine preparation treatment of the present invention, after taking 2 courses for the treatment of,
Quan Yu, follow-up, do not recur so far.
Case 4, Lin, man, 51 years old, Heilungkiang grand celebration people.Patient has a stomach-ache gasteremphraxis, and nausea, belch gas, appetite is poor, powerless, disappear
It is thin.Used many medicines, have only served temporary analgesic, will recur after a time, it is impossible to fully recover.Take Chinese medicine system of the present invention
Agent, after taking 2 courses for the treatment of, the gasteremphraxis that has a stomach-ache symptom disappears substantially, after taking the 3rd course for the treatment of, recovery from illness, after 1 year follow-up do not recur.
Case 5, Guo, female, 65 years old, Anshan, liaoning Province people.Contract heat under patient's chest, the support back of the body, gas of belching, there is nausea and vomiting, mouth
Bitter, dry.Hospital admission is removed, does gastrocopy, is diagnosed as atrophic gastritis, peristole is powerless, used many drug therapies, no
See improvement.Chinese medicine preparation of the present invention is taken, after taking 1 course for the treatment of, nausea and vomiting, bitter taste dry mouth symptom disappear substantially, continue to take
After a course for the treatment of, nausea and vomiting, bitter taste dry mouth symptom are wholly absent, and follow-up is not recurred so far.
Case 6, what certain, man, 57 years old, Sichuan people from Chengdu.Patient suffers from aerogastria, and all day is in great pain, took several drugses and controls
Treat, have no any improvement, after taking 1 course for the treatment of, symptom has been alleviated, and continues after taking 2 courses for the treatment of, and symptom disappears, recovery from illness, and 1
Follow-up is not recurred after year.
It is described above, be only presently preferred embodiments of the present invention, any formal limitation not done to the present invention, it is every according to
Any simply modification, the equivalent variations made according to the technical spirit of the present invention to above example, each fall within the protection of the present invention
Within the scope of.
Claims (5)
1. a kind of effectively alleviate gaseous distention and the Chinese medicine composition of hiccup, it is characterised in that the Chinese medicine composition is by under
The traditional Chinese medicine of parts by weight forms：Inula britannica chinensis 10-20 parts, excrementum pteropi 10-30 parts, tuber of dwarf lilyturf 35-50 part, Chinese Fevervine Herb 40-60 parts, bavin
Hu 40-60 parts, dried immature fruit of citron orange 35-50 parts, rough gentian 5-8 parts, lycopodium calvatum 35-50 parts.
2. a kind of effectively alleviation gaseous distention according to claim 1 and the Chinese medicine composition of hiccup, it is characterised in that described
Chinese medicine composition according to the traditional Chinese medicine of lower parts by weight by forming：16 parts of Inula britannica chinensis, 20 parts of excrementum pteropi, 50 parts of the tuber of dwarf lilyturf, Chinese Fevervine Herb
40 parts, 40 parts of radix bupleuri, 35 parts of the dried immature fruit of citron orange, 5 parts of rough gentian, 40 parts of lycopodium calvatum.
3. a kind of effectively alleviation gaseous distention according to claim 1 and the Chinese medicine composition of hiccup, it is characterised in that described
Chinese medicine composition according to the traditional Chinese medicine of lower parts by weight by forming：10 parts of Inula britannica chinensis, 15 parts of excrementum pteropi, 45 parts of the tuber of dwarf lilyturf, Chinese Fevervine Herb
40 parts, 50 parts of radix bupleuri, 35 parts of the dried immature fruit of citron orange, 6 parts of rough gentian, 40 parts of lycopodium calvatum.
4. a kind of effectively alleviation gaseous distention and the Chinese medicine composition of hiccup according to claim any one of 1-3, its feature
It is, the Chinese medicine composition can be prepared into pharmaceutically acceptable formulation.
5. a kind of effectively alleviation gaseous distention according to claim 4 and the Chinese medicine composition of hiccup, it is characterised in that pharmacy
Acceptable formulation is selected from decoction, pill, pulvis, capsule, tablet or electuary.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653659A (en) * | 2018-07-30 | 2018-10-16 | 佛山科学技术学院 | A kind of Chinese medicine composition and preparation method thereof that gaseous distention and hiccup is effectively relieved |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104208362A (en) * | 2014-09-22 | 2014-12-17 | 李华 | Traditional Chinese medicine preparation for treating gaseous distention and preparation method thereof |
| CN106075269A (en) * | 2016-07-27 | 2016-11-09 | 张志杰 | A kind of Chinese medicine composition treating flatulence |
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2017
- 2017-08-29 CN CN201710756364.6A patent/CN107582831A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104208362A (en) * | 2014-09-22 | 2014-12-17 | 李华 | Traditional Chinese medicine preparation for treating gaseous distention and preparation method thereof |
| CN106075269A (en) * | 2016-07-27 | 2016-11-09 | 张志杰 | A kind of Chinese medicine composition treating flatulence |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653659A (en) * | 2018-07-30 | 2018-10-16 | 佛山科学技术学院 | A kind of Chinese medicine composition and preparation method thereof that gaseous distention and hiccup is effectively relieved |
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Application publication date: 20180116 |