CN109568245A - A kind of compound polyphenol anti-acne essence cream - Google Patents
A kind of compound polyphenol anti-acne essence cream Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The present invention relates to technical field of skin care, more particularly to a kind of compound polyphenol anti-acne essence cream, including compound polyphenol, weight percentage of the compound polyphenol in the anti-acne essence cream is 3~8%, the compound polyphenol comprises the following components in parts by weight: 5 parts of Fructus Forsythiae berry extract, 6 parts of Leonurus extract, 8 parts of Salvia root P.E, 5 parts of the grey extract of thatch, 20 parts of propolis extract, 3 parts of rhizome of chuanxiong root extract, 2 parts of common cnidium fruit P.E, also contains moisturizer, emollient, emulsifier, carbomer in the anti-acne essence cream.The present invention is added the anti-acne essence that compound polyphenol is prepared and can repair damaged tissues and accelerate wound healing, can not stay or reduce the formation of acne scar, and the pigment deposition that desalination azoles sore is left rapidly.
Description
Technical field
The present invention relates to technical field of skin care more particularly to a kind of compound polyphenol anti-acne essence creams.
Background technique
Whelk is also known as azoles sore, is a kind of infective inflammation of pilosebaceous follicle.Acne mainly by hormone metabolic effect, is led to
It is often hyperfunction related with 3male hormone secretion.Hebetic young boys and girls and skin quality are that Oily person is easier to occur, in addition, just
Secret, irregular menstruation, excessively edible seafood may also induce with spicy food.Acne has a progressive process: being excited
Element influence sebum secretion increase (fat granule) → abnormal keratinization of hair follicle cause sebaceous glands row rouge be obstructed (whelk) → by acne bar
The microorganism infections such as bacterium (acne) → formation acne scars and pigmentation (acne scars).As it can be seen that the initial stage of acne is the youth
Acne, sequelae are then scar and pigmentation.
It is influenced since modern people's rhythm of life is fast, and by various environment, or often stays up late excessive internal heat, the long acne of skin,
It leaves acne print after small pox elimination to be difficult to eliminate, the intensely dark pool so that skin seems.The essence of current skin care item in the market
Liquid or essence cream are most of containing preservative, fungicide, fragrance, synthetic dyestuff, ethyl alcohol etc., and consumer is such in long-time service
After product, skin will appear allergic reaction or pigment deposition, and even more serious even can induce Other diseases, and anti-acne effect is not shown
It writes.It causes great trouble for consumer, while making the consumer of most skin sensitivity dare not be using the skin care of anti-acne
Product.
Therefore, for small pox crowd, in order to completely remove small pox acne print, in addition to paying attention to diet, living habit
Deng a safely and effectively product for resolving poxes is essential.
Summary of the invention
In view of this, being added multiple the object of the present invention is to provide a kind of compound polyphenol anti-acne essence cream and preparation method thereof
Damaged tissues can be repaired and accelerate wound healing by closing the anti-acne essence that polyphenol is prepared, and can not stay or reduce the shape of acne scar
At, and the pigment deposition that desalination azoles sore is left rapidly.
The present invention solves above-mentioned technical problem by following technological means:
A kind of compound polyphenol anti-acne essence cream, including compound polyphenol, the compound polyphenol is in the anti-acne essence cream
Weight percentage is 3~8%, and the compound polyphenol includes Fructus Forsythiae berry extract, Leonurus extract, Salvia root P.E, thatch
Grey extract, propolis extract, rhizome of chuanxiong root extract, common cnidium fruit P.E.
Anti-acne essence cream by adopting the above technical scheme is extracted with Radix Salviae Miltiorrhizae, Fructus Forsythiae fruit, motherwort, Mao Cangsu, frutus cnidii
The herbal polyphenol of fat eliminating removing toxic substances is compounded with the rhizome of chuanxiong extract of activating microcirculation and removing stasis medicinal, is capable of the pore of effectively shrinkage expansion, is reduced seborrhagia
Out to skin surface, pore can also be obviously reduced；The fat eliminating solution that Radix Salviae Miltiorrhizae, Fructus Forsythiae fruit, motherwort, Mao Cangsu, frutus cnidii extract
Malicious book on Chinese herbal medicine polyphenol is compounded with the propolis extract of eliminating inflammation and expelling toxin, can effectively prevent whelk, azoles sore, additionally it is possible to effectively reparation azoles
Scar trace mitigates and eliminates azoles sore pigment deposition, the triple role for playing anti-acne, going acne print, going acne scar；In addition, Radix Salviae Miltiorrhizae, Fructus Forsythiae
Fruit, motherwort, Mao Cangsu, rhizome of chuanxiong root, the extract of frutus cnidii and propolis extract synergistic effect, can largely press down
Corneocyte processed synthesizes 5α-reductase, to prevent seborrhea and acne.
Further, the compound polyphenol comprises the following components in parts by weight: 3~7 parts of Fructus Forsythiae berry extract, motherwort are extracted
6~8 parts of object, 5~10 parts of Salvia root P.E, 4~8 parts of the grey extract of thatch, 15~25 parts of propolis extract, rhizome of chuanxiong root extract
2~5 parts, 1~3 part of common cnidium fruit P.E.
Further, the compound polyphenol comprises the following components in parts by weight: 5 parts of Fructus Forsythiae berry extract, Leonurus extract 6
Part, 8 parts of Salvia root P.E, 5 parts of the grey extract of thatch, 20 parts of propolis extract, 3 parts of rhizome of chuanxiong root extract, common cnidium fruit P.E 2
Part.
Further, in anti-acne essence cream also containing 1.8~2.2% skin-active ingredient, the skin-active ingredient is nicotinoyl
Amine.
Niacinamide can promote skin to the various extracted form natural plants in compound polyphenol with Cucumber Extract, infiltration cuticula
The absorption of object improves hair follicle keratinization, being capable of more effectively antibacterial, anti-inflammatory and oil-control.
Further, also contain moisturizer, emollient, emulsifier, carbomer in the anti-acne essence cream.
Further, the moisturizer includes glycerol, Natrulon H-10, trehalose.
Further, the emollient includes cetostearyl alcohol, dimethyl silicone polymer and nutmeg isopropyl ester.
Further, the emulsifier includes stearine, PEG-100 stearate and PEG-20 stearate.
Further, the anti-acne essence cream includes following components in percentage by weight: compound polyphenol 3~8%, niacinamide
2.0~2.2%, glycerol 4.0~4.5%, Natrulon H-10 1.8~2.2%, trehalose 0.8~1.2%, cetostearyl alcohol 1.2
~2.2%, dimethyl silicone polymer 1.0~1.5%, nutmeg isopropyl ester 3.6~5%, stearine 0.4~0.6%,
PEG-100 stearate 0.4~0.6%, PEG-20 stearate 0.15~0.25%, carbomer 0.08~0.12%, it is remaining
For distilled water.
Further, the anti-acne essence cream comprises the following components in parts by weight: compound polyphenol 5%, niacinamide 2.1%, sweet
Oily 4.3%, Natrulon H-10 2.0%, trehalose 1.0%, cetostearyl alcohol 1.5%, dimethyl silicone polymer 1.3%, Pork and beans
Cool isopropyl ester 4.0%, stearine 0.5%, PEG-100 stearate 0.5%, PEG-20 stearate 0.2%, card wave
Nurse 0.1%, remainder are distilled water.
Essence in anti-acne essence cream of the invention is pure Chinese medicinal preparation, is free of antibiotics, has bactericidal,
The effect of anti-inflammatory skin care, can control fat secretion, prevents grease excessive secretion to block hair follicle, has and repair damaged tissues
And the effect of accelerating wound healing, the formation of acne scar can not be stayed or reduce, and the pigment deposition that desalination azoles sore is left rapidly.
Specific embodiment
Below with reference to specific embodiment, the present invention is described in detail:
A kind of compound polyphenol anti-acne essence cream of the invention, including compound polyphenol, skin-active ingredient, moisturizer, emollient, cream
Agent, carbomer, wherein compound polyphenol comprises the following components in parts by weight: 3~7 parts of Fructus Forsythiae berry extract, Leonurus extract
6~8 parts, 5~10 parts of Salvia root P.E, 4~8 parts of the grey extract of thatch, 15~25 parts of propolis extract, rhizome of chuanxiong root extract 2
~5 parts, 1~3 part of common cnidium fruit P.E；Skin-active ingredient is niacinamide；Moisturizer includes glycerol, Natrulon H-10, trehalose；Profit
Skin agent includes cetostearyl alcohol, dimethyl silicone polymer and nutmeg isopropyl ester；Emulsifier includes stearine, PEG-
100 stearates and PEG-20 stearate.
Specifically, anti-acne essence cream of the invention includes following components in percentage by weight: compound polyphenol 3~8%, nicotinoyl
Amine 2.0~2.2%, glycerol 4.0~4.5%, Natrulon H-10 1.8~2.2%, trehalose 0.8~1.2%, cetostearyl alcohol
1.2~2.2%, dimethyl silicone polymer 1.0~1.5%, nutmeg isopropyl ester 3.6~5%, stearine 0.4~
0.6%, PEG-100 stearate 0.4~0.6%, PEG-20 stearate 0.15~0.25%, carbomer 0.08~
0.12%, remainder is distilled water.
Above-mentioned anti-acne essence cream the preparation method is as follows:
It takes carbomer and distilled water with homogenizer homogeneous to no particle that is uniformly dispersed, water, glycerol, polyglycereol-is then added
10, trehalose mixes, and is transferred in main phase pot, is heated with stirring to 85 DEG C, keeps the temperature 30min, obtains main phase material, take cetearyl alcohol
Alcohol, dimethyl silicone polymer, nutmeg isopropyl ester, stearine, PEG-100 stearate, PEG-20 stearate add
Enter in oily phase pot, be heated to 80 DEG C, stir to complete liquefied, then mixed with main phase material, under conditions of vacuum, 80 DEG C
Matter 5min, and 10min is kept the temperature, 48 DEG C are then cooled to, niacinamide and compound polyphenol is added, stirs and evenly mixs, is cooled to room temperature, go out
Bacterium obtains anti-acne essence cream.According to above-mentioned preparation method and formula as below preparation anti-acne essence cream.
Embodiment one
Compound polyphenol in the anti-acne essence cream of the present embodiment include 3 parts of Fructus Forsythiae berry extract, 8 parts of Leonurus extract,
8 parts of the grey extract of 5 parts of Salvia root P.E, thatch, 25 parts of propolis extract, 5 parts of rhizome of chuanxiong root extract, 1 part of common cnidium fruit P.E.
The anti-acne essence cream of the present embodiment includes following components in percentage by weight: compound polyphenol 3%, niacinamide 1.8, sweet
Oily 4.5%, Natrulon H-10 1.8%, trehalose 0.8%, cetostearyl alcohol 2.2%, dimethyl silicone polymer 1.5%, Pork and beans
Cool isopropyl ester 5%, stearine 0.6%, PEG-100 stearate 0.6%, PEG-20 stearate 0.15%, card wave
Nurse 0.08%, remainder are distilled water.
Embodiment two
Compound polyphenol in the anti-acne essence cream of the present embodiment include 5 parts of Fructus Forsythiae berry extract, 6 parts of Leonurus extract,
5 parts of the grey extract of 8 parts of Salvia root P.E, thatch, 20 parts of propolis extract, 3 parts of rhizome of chuanxiong root extract, 2 parts of common cnidium fruit P.E.
The anti-acne essence cream of the present embodiment includes following components in percentage by weight: compound polyphenol 5%, niacinamide 2.0%,
Glycerol 4.3%, Natrulon H-10 2.0%, trehalose 1.0%, cetostearyl alcohol 1.5%, dimethyl silicone polymer 1.3%, meat
Cardamom isopropyl ester 4.0%, stearine 0.5%, PEG-100 stearate 0.5%, PEG-20 stearate 0.2%, card
Wave nurse 0.1%, remainder are distilled water.
Embodiment three
Compound polyphenol in the anti-acne essence cream of the present embodiment includes 4 parts of Fructus Forsythiae berry extract, Leonurus extract 6.5
Part, 6 parts of Salvia root P.E, 6 parts of the grey extract of thatch, 15 parts of propolis extract, 2.5 parts of rhizome of chuanxiong root extract, frutus cnidii extract
1.5 parts of object.
The anti-acne essence cream of the present embodiment includes following components in percentage by weight: compound polyphenol 3~8%, niacinamide
2.0%, glycerol 4.3%, Natrulon H-10 2.0%, trehalose 1.0%, cetostearyl alcohol 1.5%, dimethyl silicone polymer
1.3%, nutmeg isopropyl ester 4.0%, stearine 0.5%, PEG-100 stearate 0.5%, PEG-20 stearate
0.2%, carbomer 0.1%, remainder are distilled water.
Example IV
Compound polyphenol in the anti-acne essence cream of the present embodiment include 6 parts of Fructus Forsythiae berry extract, 7 parts of Leonurus extract,
7 parts of the grey extract of 7 parts of Salvia root P.E, thatch, 22 parts of propolis extract, 2 parts of rhizome of chuanxiong root extract, common cnidium fruit P.E 2.5
Part.
The anti-acne essence cream of the present embodiment includes following components in percentage by weight: compound polyphenol 3~8%, niacinamide
2.0%, glycerol 4.3%, Natrulon H-10 2.0%, trehalose 1.0%, cetostearyl alcohol 1.5%, dimethyl silicone polymer
1.3%, nutmeg isopropyl ester 4.0%, stearine 0.5%, PEG-100 stearate 0.5%, PEG-20 stearate
0.2%, carbomer 0.1%, remainder are distilled water.
Embodiment five
Compound polyphenol in the anti-acne essence cream of the present embodiment includes 7 parts of Fructus Forsythiae berry extract, Leonurus extract 7.5
Part, 10 parts of Salvia root P.E, 6.5 parts of the grey extract of thatch, 23 parts of propolis extract, 4 parts of rhizome of chuanxiong root extract, frutus cnidii extract
3 parts of object.
The anti-acne essence cream of the present embodiment includes following components in percentage by weight: compound polyphenol 8%, niacinamide 2.2%,
Glycerol 4.0%, Natrulon H-10 2.2%, trehalose 1.2%, cetostearyl alcohol 1.2%, dimethyl silicone polymer 1.0%, meat
Cardamom isopropyl ester 3.6%, stearine 0.4%, PEG-100 stearate 0.4%, PEG-20 stearate 0.25%,
Carbomer 0.12%, remainder are distilled water.
Detection test: the anti-acne essence cream is measured by the quantity of 5α-reductase to 5α-reductase in human keratinized cell
Active inhibitory effect, the quantity that the compound polyphenol of measurement result discovery 0.075% can reduce 5α-reductase reach 16%,
The quantity that 0.10% compound polyphenol can reduce 5α-reductase reaches 43%, and 0.15% compound polyphenol can reduce 5 α-also
The quantity of protoenzyme reaches 64%.
It is compared with anti-acne essence cream prepared by embodiment two with blank, compound polyphenol is free of in blank emulsion herein,
Anti-acne essence cream prepared by other compositions and embodiment two, pore dia, knot are observed and measured using Vis scan instrument
Fruit discovery, the anti-acne essence cream of embodiment two reduce pore dia.
The above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to preferred embodiment to this hair
It is bright to be described in detail, those skilled in the art should understand that, it can modify to technical solution of the present invention
Or equivalent replacement should all cover without departing from the objective and range of technical solution of the present invention in claim of the invention
In range.Technology not described in detail in the present invention, shape, construction portion are well-known technique.
Claims (10)
1. a kind of compound polyphenol anti-acne essence cream, which is characterized in that including compound polyphenol, the compound polyphenol is in the anti-acne essence
Weight percentage in magnificent cream is 3~8%, and the compound polyphenol includes that Fructus Forsythiae berry extract, Leonurus extract, Radix Salviae Miltiorrhizae mention
Take the grey extract of object, thatch, propolis extract, rhizome of chuanxiong root extract, common cnidium fruit P.E.
2. a kind of compound polyphenol anti-acne essence cream according to claim 1, which is characterized in that the compound polyphenol include with
The component of lower parts by weight: 3~7 parts of Fructus Forsythiae berry extract, 6~8 parts of Leonurus extract, 5~10 parts of Salvia root P.E, Mao Cangsu
4~8 parts of extract, 15~25 parts of propolis extract, 2~5 parts of rhizome of chuanxiong root extract, 1~3 part of common cnidium fruit P.E.
3. a kind of compound polyphenol anti-acne essence cream according to claim 2, which is characterized in that the compound polyphenol include with
The component of lower parts by weight: 5 parts of Fructus Forsythiae berry extract, 6 parts of Leonurus extract, 8 parts of Salvia root P.E, 5 parts of the grey extract of thatch,
20 parts of propolis extract, 3 parts of rhizome of chuanxiong root extract, 2 parts of common cnidium fruit P.E.
4. a kind of compound polyphenol anti-acne essence cream according to claim 3, which is characterized in that in the anti-acne essence cream also
Containing 1.8~2.2% skin-active ingredient, the skin-active ingredient is niacinamide.
5. a kind of compound polyphenol anti-acne essence cream according to claim 4, which is characterized in that in the anti-acne essence cream also
Contain moisturizer, emollient, emulsifier, carbomer.
6. a kind of compound polyphenol anti-acne essence cream according to claim 5, which is characterized in that the moisturizer includes sweet
Oil, Natrulon H-10, trehalose.
7. a kind of compound polyphenol anti-acne essence cream according to claim 6, which is characterized in that the emollient includes spermaceti
Stearyl alcohol, dimethyl silicone polymer and nutmeg isopropyl ester.
8. a kind of compound polyphenol anti-acne essence cream according to claim 7, which is characterized in that the emulsifier includes glycerol
Stearate, PEG-100 stearate and PEG-20 stearate.
9. a kind of compound polyphenol anti-acne essence cream according to claim 8, which is characterized in that the anti-acne essence cream includes
Following components in percentage by weight: compound polyphenol 3~8%, niacinamide 2.0~2.2%, glycerol 4.0~4.5%, Natrulon H-10
1.8~2.2%, trehalose 0.8~1.2%, cetostearyl alcohol 1.2~2.2%, dimethyl silicone polymer 1.0~1.5%, meat
Cardamom isopropyl ester 3.6~5%, stearine 0.4~0.6%, PEG-100 stearate 0.4~0.6%, PEG-20 are hard
Resin acid ester 0.15~0.25%, carbomer 0.08~0.12%, remainder are distilled water.
10. a kind of compound polyphenol anti-acne essence cream according to claim 9, which is characterized in that the anti-acne essence cream packet
Include the component of following parts by weight: compound polyphenol 5%, niacinamide 2.1%, glycerol 4.3%, Natrulon H-10 2.0%, trehalose
1.0%, cetostearyl alcohol 1.5%, dimethyl silicone polymer 1.3%, nutmeg isopropyl ester 4.0%, stearine
0.5%, PEG-100 stearate 0.5%, PEG-20 stearate 0.2%, carbomer 0.1%, remainder are distilled water.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112121000A (en) * | 2020-10-12 | 2020-12-25 | 北京蜜慕科技有限公司 | Propolis acne-removing balancing base solution and preparation method thereof |
| CN114504537A (en) * | 2020-12-25 | 2022-05-17 | 邱天英 | Acne removing formula for stubborn acne |
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