CN109568203B - Cosmetic composition with whitening and skin brightening effects - Google Patents
Cosmetic composition with whitening and skin brightening effects Download PDFInfo
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- CN109568203B CN109568203B CN201811550501.1A CN201811550501A CN109568203B CN 109568203 B CN109568203 B CN 109568203B CN 201811550501 A CN201811550501 A CN 201811550501A CN 109568203 B CN109568203 B CN 109568203B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
A cosmetic composition with skin whitening and brightening effects comprises effective amounts of nicotinamide, ascorbyl glucoside, hydrolyzed glycosaminoglycan, kakakadu plum extract, and yeast extract. The weight percentages of the components are as follows: 1-4% of nicotinamide, 0.1-1% of ascorbyl glucoside, 0.01-0.5% of hydrolyzed glycosaminoglycan, 0.1-2% of kakadu plum extract, 0.1-10% of yeast extract and 82.5-98.69% of cosmetic matrix. The yeast extract used in the cosmetic composition contains amino acids, peptides, nucleotides, vitamins, etc., the amino acids are beneficial to collagen synthesis, and the nucleotides can promote metabolism, increase protein synthesis speed, improve skin anti-free radical ability, etc.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a cosmetic composition with whitening and skin brightening effects.
Background
With the improvement of living standard, modern consumers are more and more pursuing the natural, healthy, tender, white and bright skin state. However, in the present situation, many people suffer from skin problems such as color spots, dull yellow, and dull luster.
The causes of pigmentation and color spots are complicated, such as genetic factors, endocrine disorders, environmental pollution, ultraviolet irradiation, etc., and the pigmentation or color spots caused by any cause are primarily caused by melanin pigmentation. Melanocytes, which are capable of producing melanin, are present in the basal layer of the epidermis of humans. Melanin is the largest factor determining the color of human skin. Normally, melanin can absorb excessive ultraviolet rays to protect the body, but when melanin cells are not metabolized in time and accumulate and deposit on the epidermis, the skin becomes inhomogeneous, and color spots, freckles and the like appear.
With the improvement of scientific level, research on whitening and freckle removing mechanisms, whitening and freckle removing raw materials and scientific evaluation of whitening and freckle removing effects is more and more intensive. Vitamin C, also called ascorbic acid, can effectively reduce the activity of tyrosinase, thereby preventing the generation of melanocytes. Vitamin C is one of the most representative additives that have been used in whitening products for the first time, and is also one of the most representative and safest whitening ingredients. Vitamin C is highly active, but is extremely unstable, is easily destroyed by light, heat, and oxygen to reduce its activity, and is easily dehydrated in an acidic solution to change its structure. The vitamin C glucoside is a vitamin C derivative with good stability, and has remarkable effects of promoting collagen generation, accelerating metabolism, whitening and resisting aging.
Disclosure of Invention
The purpose of the invention is: provided is a cosmetic composition having skin whitening and brightening effects, which is highly safe and stable, and has skin whitening and skin dullness and wrinkle improving effects.
In order to achieve the purpose, the invention adopts the technical scheme that: the cosmetic composition with the effects of whitening and brightening the skin is characterized by comprising the following components in percentage by mass:
1 to 4 percent of nicotinamide, 0.1 to 1 percent of ascorbyl glucoside,
0.01-0.5% of hydrolyzed aminodextran, 0.1-2% of kakadu plum extract,
0.1-10% of yeast extract and 82.5-98.69% of cosmetic matrix.
The composition has the following effects:
the cosmetic composition uses nicotinamide with nicotinic acid content less than 100 PPM. It has been found that prolonged topical application of niacinamide reduces pigmented spots in the facial skin of caucasians and asians by inhibiting the transport of melanosomes from melanocytes to keratinocytes. With the inhibition of the delivery pathway, melanocytes stop producing melanin. Topical niacinamide is also effective in preventing sallowness by a mechanism that may prevent protein glycation, the end product of which is a cross-linked yellowish brown protein that accumulates in the skin. The final usage amount is 1-4% according to the literature data of effectiveness and safety.
The ascorbyl glucoside adopted by the cosmetic composition is one of the derivatives of the vitamin C, and retains all the biological activity of the vitamin C; in addition, it has a glycosidic bond in its molecular structure, is not easily decomposed and is very stable, and is considered to be the most stable derivative of vitamin C. The ascorbyl glucoside is identified as one of the whitening additives by the ministry of health, and the action mechanism of the ascorbyl glucoside is to inhibit the activity of tyrosinase, reduce the formation of melanin, accelerate the formed melanin to be reduced to the original state and reduce pigmentation. The ascorbyl glucoside also has the effects of promoting collagen synthesis, and improving skin wrinkle and rough and dry skin.
The hydrolyzed glycosaminoglycan used in the cosmetic composition is one of viscous polysaccharides, and has effects of regulating skin moisture content, nourishing skin, and increasing skin elasticity. Raw materials producers tested emulsions in vitro containing 0.5% hydrolyzed aminodextran and vitamin C: transdermal vitamin C levels were tested on a three-dimensional skin model and trans-epithelial active ingredient transport was assessed by high performance liquid chromatography.
The results show that after 2 hours, the bioavailability of vitamin C increases by about 21%, and it is believed that hydrolyzing the aminodextran is advantageous to improve the bioavailability of vitamin C. This material was purchased from ResPharma. The kakadu plum extract selected by the cosmetic composition is extracted from Kakaduplum (kakadu plum) which is a plant with the highest vitamin C content in the world, and also contains tannic acid, ellagic acid polyphenol components, vitamin A and vitamin E, so that the cosmetic composition can effectively reduce wrinkle generation and improve skin glossiness through clinical verification. This material was purchased from Southern Cross botanicals.
The yeast extract used in the cosmetic composition contains amino acids, peptides, nucleotides, vitamins, etc., the amino acids are beneficial to collagen synthesis, and the nucleotides can promote metabolism, increase protein synthesis speed, improve skin anti-free radical ability, etc. The yeast extract used in the present invention includes, but is not limited to, one or more of yeast extract, tectorial yeast fermentation product filtrate, yeast fermentation product, yeast lysate extract, and yeast extract. Based on the comprehensive consideration of the safety mass fraction and the efficacy of the medicine on cytotoxicity, the dosage is 0.1-10%. Can be purchased from various yeast manufacturers all over the world.
The solvent for the cosmetic base of the cosmetic composition of the present invention is deionized water and the humectant in the cosmetic base of the cosmetic composition of the present invention includes, but is not limited to, one or more of glycerin, propylene glycol, dipropylene glycol, butylene glycol, 1, 2-hexanediol, 1, 2-pentanediol, corn gluten amino acids, caprylyl glycol, ethylhexylglycerin, sorbitol, β -glucan, saccharide isomers, diglycerol, polyethylene glycol-32, biosaccharide-1, betaine, trehalose, sodium polyglutamate, and sodium hyaluronate.
The thickener in the cosmetic base of the cosmetic composition of the present invention includes, but is not limited to, at least one of xanthan gum, acacia, carbomer, polyacrylate crosspolymer-6, ammonium acryloyldimethyltaurate/VP copolymer, acrylic acid/C10-30 alkanol acrylate crosspolymer, sodium polyacrylate, ammonium acryloyldimethyltaurate/behenyl polyether-25 methacrylate crosspolymer, gellan gum, sodium acrylate copolymer, ammonium acryloyldimethyltaurate/behenyl polyether-25 methacrylate crosspolymer, sodium polyacrylyldimethyltaurate, polyvinylpyrrolidone, tara gum, and sclerotium rolfsii gum.
The emollient in the cosmetic matrix of the cosmetic composition is one or more of vegetable oil, synthetic oil and mineral oil.
The emulsifier in the cosmetic base of the cosmetic composition of the present invention includes, but is not limited to, one or more of PEG-20 methyl glucose sesquistearate, methyl glucoside sesquistearate, lecithin derivatives, glyceryl stearate, polyoxyethylene fatty acid esters, polyglyceryl fatty acid esters, polysorbate, sucrose fatty acid esters, sorbitan fatty acid esters, and alkyl glucosides.
The skin conditioning agent in the cosmetic matrix of the cosmetic composition of the present invention includes but is not limited to dipotassium glycyrrhizinate, allantoin, bisabolol and one or more of anti-allergic antipruritic agents, soothing anti-inflammatory agents of some plant origin.
The chelating agent in the cosmetic matrix of the cosmetic composition is one of EDTA-2Na and EDTA-4 Na.
The preservatives in the cosmetic base of the cosmetic compositions of the present invention include, but are not limited to, one or more of parabens, phenoxyethanol, chlorphenesin, sodium benzoate, potassium sorbate, phenylethyl alcohol, and p-hydroxyacetophenone.
The cosmetic composition of the present invention further comprises one or more of conventional photoprotective, antioxidant and pH adjusting agents in a cosmetic base.
Drawings
FIG. 1 is a graph showing the variation result of the L value of the full-face luminance according to the present invention.
Fig. 2 is a graph showing the change of local wrinkles in the present invention.
FIG. 3 is a graph of a quantitative analysis of topical skin spots of the present invention.
Fig. 4 is a full face luminance analysis of the present invention, with the left side before use and the right side after 7 consecutive days of use.
Fig. 5 is a diagram illustrating the wrinkle area and effect of the present invention.
FIG. 6 is a graph of the regions before and after the quantitative analysis of the present invention.
FIG. 7 is a visual representation of the comparative effect of the inventive plaques.
Detailed Description
The present invention will be further described with reference to the following specific examples. These examples are provided only for the purpose of further illustrating the present invention and are not intended to limit the present invention and do not represent a limitation on the scope of the present invention.
The invention can inhibit the activity of tyrosinase and reduce partial melanin, thereby realizing the effects of removing yellow spots, whitening and brightening the skin. In addition, the collagen production can be promoted, the wrinkle production can be effectively reduced, and the skin fineness and glossiness can be improved.
Example 1
A cosmetic composition with whitening and skin brightening effects is prepared into a mask essence, and comprises the following raw material components in percentage by weight:
84.51% of deionized water, 0.1% of EDTA-2Na, 0.2% of allantoin,
0.1 percent of dipotassium glycyrrhizinate, 3 percent of glycerol, 5 percent of dipropylene glycol,
Glycerol polyether-262%, trehalose 1%, xanthan gum 0.2%,
0.3 percent of sodium acrylate copolymer,
0.3 percent of acryloyl dimethyl ammonium taurate/VP copolymer, 0.03 percent of citric acid,
0.12 percent of sodium citrate, 0.1 percent of sodium sulfite, 0.07 percent of arginine,
Nicotinamide 1%, ascorbyl glucoside 0.1%, hydrolyzed glycosaminoglycans 0.01%, kakadu plum
0.1 percent of extract, 0.1 percent of yeast extract,
0.1 percent of filtrate of fermentation product of tectorial membrane yeast, 0.1 percent of lecithin,
0.2 percent of phenoxyethanol, 0.15 percent of chlorphenesin, 0.5 percent of 1, 2-hexanediol,
0.5 percent of 1, 2-pentanediol, 0.1 percent of PEG-40 hydrogenated castor oil and 0.01 percent of essence.
The preparation process of the facial mask essence prepared from the cosmetic composition comprises the following steps:
adding deionized water, EDTA-2Na and allantoin into a water phase pot, heating and stirring to 75-80 ℃. As phase A;
adding xanthan gum, acrylic acid (ester) copolymer sodium, acryloyl dimethyl ammonium taurate/VP copolymer and lecithin into glycerol, dipropylene glycol, glyceryl polyether-26, 1, 2-hexanediol and 1, 2-pentanediol, and uniformly mixing and stirring. As phase B;
and thirdly, pumping the A, B phase into an emulsifying cylinder for homogenizing for 3-8 minutes, and stirring and dispersing uniformly. Preserving the heat for 10 minutes and beginning to cool;
dissolving citric acid, sodium citrate, sodium sulfite, ascorbyl glucoside, nicotinamide, arginine and dipotassium glycyrrhizinate in deionized water, and dispersing; as phase C;
and (V) when the temperature is reduced to 35-40 ℃, sequentially adding the prepared C phase, trehalose, yeast extract, the membrane-covered yeast fermentation product filtrate, essence, PEG-40 hydrogenated castor oil, phenoxyethanol and chlorphenesin. Stirring and dispersing uniformly to obtain the product.
Example 2
A cosmetic composition with whitening and skin brightening effects is prepared into a mask essence, and comprises the following raw material components in percentage by weight:
82.47% of deionized water, 0.1% of EDTA-2Na, 0.2% of allantoin,
0.1 percent of dipotassium glycyrrhizinate, 3 percent of glycerol, 5 percent of dipropylene glycol,
Glycerol polyether-262%, trehalose 1%, xanthan gum 0.2%,
0.3 percent of sodium acrylate copolymer,
0.3 percent of acryloyl dimethyl ammonium taurate/VP copolymer, 0.03 percent of citric acid,
0.12 percent of sodium citrate, 0.1 percent of sodium sulfite, 0.07 percent of arginine,
Nicotinamide 2%, ascorbyl glucoside 0.3%, hydrolyzed glycosaminoglycan 0.05%, kakadu plum extract 0.5%, yeast extract 0.3%,
0.3 percent of filtrate of fermentation product of tectorial membrane yeast, 0.1 percent of lecithin,
0.2 percent of phenoxyethanol, 0.15 percent of chlorphenesin, 0.5 percent of 1, 2-hexanediol,
0.5 percent of 1, 2-pentanediol, 0.1 percent of PEG-40 hydrogenated castor oil and 0.01 percent of essence.
The preparation process of the facial mask essence prepared from the cosmetic composition comprises the following steps:
adding deionized water, EDTA-2Na and allantoin into a water phase pot, heating and stirring to 75-80 ℃.
As phase A;
adding xanthan gum, acrylic acid (ester) copolymer sodium, acryloyl dimethyl ammonium taurate/VP copolymer and lecithin into glycerol, dipropylene glycol, glyceryl polyether-26, 1, 2-hexanediol and 1, 2-pentanediol, and uniformly mixing and stirring. As phase B;
and thirdly, pumping the A, B phase into an emulsifying cylinder for homogenizing for 3-8 minutes, and stirring and dispersing uniformly. Preserving the heat for 10 minutes and beginning to cool;
dissolving citric acid, sodium citrate, sodium sulfite, ascorbyl glucoside, nicotinamide, arginine and dipotassium glycyrrhizinate in deionized water, and dispersing; as phase C;
and (V) when the temperature is reduced to 35-40 ℃, sequentially adding the prepared C phase, trehalose, yeast extract, the membrane-covered yeast fermentation product filtrate, essence, PEG-40 hydrogenated castor oil, phenoxyethanol and chlorphenesin. Stirring and dispersing uniformly to obtain the product.
Example 3
A cosmetic composition with whitening and skin brightening effects is prepared into a mask essence, and comprises the following raw material components in percentage by weight:
76.32 percent of deionized water, 0.1 percent of EDTA-2Na, 0.2 percent of allantoin,
0.1 percent of dipotassium glycyrrhizinate, 3 percent of glycerol, 5 percent of dipropylene glycol,
Glycerol polyether-262%, trehalose 1%, xanthan gum 0.2%,
0.3 percent of sodium acrylate copolymer,
0.3 percent of acryloyl dimethyl ammonium taurate/VP copolymer, 0.03 percent of citric acid,
0.12 percent of sodium citrate, 0.1 percent of sodium sulfite, 0.07 percent of arginine,
3% of nicotinamide, 0.5% of ascorbyl glucoside, 0.1% of hydrolyzed glycosaminoglycan, 2% of kakadu plum extract, 2% of yeast extract,
2 percent of filtrate of fermentation product of the coated saccharomycetes, 0.1 percent of lecithin,
0.2 percent of phenoxyethanol, 0.15 percent of chlorphenesin, 0.5 percent of 1, 2-hexanediol,
0.5 percent of 1, 2-pentanediol, 0.1 percent of PEG-40 hydrogenated castor oil and 0.01 percent of essence.
The preparation process of the facial mask essence prepared from the cosmetic composition comprises the following steps:
adding deionized water, EDTA-2Na and allantoin into a water phase pot, heating and stirring to 75-80 ℃. As phase A;
adding xanthan gum, acrylic acid (ester) copolymer sodium, acryloyl dimethyl ammonium taurate/VP copolymer and lecithin into glycerol, dipropylene glycol, glyceryl polyether-26, 1, 2-hexanediol and 1, 2-pentanediol, and uniformly mixing and stirring. As phase B;
and thirdly, pumping the A, B phase into an emulsifying cylinder for homogenizing for 3-8 minutes, and stirring and dispersing uniformly. Preserving the heat for 10 minutes and beginning to cool;
dissolving citric acid, sodium citrate, sodium sulfite, ascorbyl glucoside, nicotinamide, arginine and dipotassium glycyrrhizinate in deionized water, and dispersing; as phase C;
and (V) when the temperature is reduced to 35-40 ℃, sequentially adding the prepared C phase, trehalose, yeast extract, the membrane-covered yeast fermentation product filtrate, essence, PEG-40 hydrogenated castor oil, phenoxyethanol and chlorphenesin. Stirring and dispersing uniformly to obtain the product.
Example 4
A cosmetic composition with whitening and skin brightening effects is prepared into a mask essence, and comprises the following raw material components in percentage by weight:
72.12 percent of deionized water, 0.1 percent of EDTA-2Na, 0.2 percent of allantoin,
0.1 percent of dipotassium glycyrrhizinate, 3 percent of glycerol, 5 percent of dipropylene glycol,
Glycerol polyether-262%, trehalose 1%, xanthan gum 0.2%,
0.3 percent of sodium acrylate copolymer,
0.3 percent of acryloyl dimethyl ammonium taurate/VP copolymer, 0.03 percent of citric acid,
0.12 percent of sodium citrate, 0.1 percent of sodium sulfite, 0.07 percent of arginine,
Nicotinamide 4%, ascorbyl glucoside 0.5%, hydrolyzed glycosaminoglycan 0.3%, kakakadu plum extract 1%, yeast extract 5%,
3 percent of filtrate of fermentation product of the coated saccharomycetes, 0.1 percent of lecithin,
0.2 percent of phenoxyethanol, 0.15 percent of chlorphenesin, 0.5 percent of 1, 2-hexanediol,
0.5 percent of 1, 2-pentanediol, 0.1 percent of PEG-40 hydrogenated castor oil and 0.01 percent of essence.
The preparation process of the facial mask essence prepared from the cosmetic composition comprises the following steps:
adding deionized water, EDTA-2Na and allantoin into a water phase pot, heating and stirring to 75-80 ℃. As phase A;
adding xanthan gum, acrylic acid (ester) copolymer sodium, acryloyl dimethyl ammonium taurate/VP copolymer and lecithin into glycerol, dipropylene glycol, glyceryl polyether-26, 1, 2-hexanediol and 1, 2-pentanediol, and uniformly mixing and stirring. As phase B;
and thirdly, pumping the A, B phase into an emulsifying cylinder for homogenizing for 3-8 minutes, and stirring and dispersing uniformly. Preserving the heat for 10 minutes and beginning to cool;
dissolving citric acid, sodium citrate, sodium sulfite, ascorbyl glucoside, nicotinamide, arginine and dipotassium glycyrrhizinate in deionized water, and dispersing; as phase C;
and (V) when the temperature is reduced to 35-40 ℃, sequentially adding the prepared C phase, trehalose, yeast extract, the membrane-covered yeast fermentation product filtrate, essence, PEG-40 hydrogenated castor oil, phenoxyethanol and chlorphenesin. Stirring and dispersing uniformly to obtain the product.
Example 5
A cosmetic composition with whitening and skin brightening effects is prepared into a mask essence, and comprises the following raw material components in percentage by weight:
70.62% of deionized water, 0.1% of EDTA-2Na, 0.2% of allantoin,
0.1 percent of dipotassium glycyrrhizinate, 3 percent of glycerol, 5 percent of dipropylene glycol,
Glycerol polyether-262%, trehalose 1%, xanthan gum 0.2%,
0.3 percent of sodium acrylate copolymer,
0.3 percent of acryloyl dimethyl ammonium taurate/VP copolymer, 0.03 percent of citric acid,
0.12 percent of sodium citrate, 0.1 percent of sodium sulfite, 0.07 percent of arginine,
4% of nicotinamide, 0.8% of ascorbyl glucoside, 0.5% of hydrolyzed glycosaminoglycan, 2% of kakadu plum extract, 3% of yeast extract,
5 percent of filtrate of fermentation product of the coated saccharomycetes, 0.1 percent of lecithin,
0.2 percent of phenoxyethanol, 0.15 percent of chlorphenesin, 0.5 percent of 1, 2-hexanediol,
0.5 percent of 1, 2-pentanediol, 0.1 percent of PEG-40 hydrogenated castor oil and 0.01 percent of essence.
The preparation process of the facial mask essence prepared from the cosmetic composition comprises the following steps:
adding deionized water, EDTA-2Na and allantoin into a water phase pot, heating and stirring to 75-80 ℃. As phase A;
adding xanthan gum, acrylic acid (ester) copolymer sodium, acryloyl dimethyl ammonium taurate/VP copolymer and lecithin into glycerol, dipropylene glycol, glyceryl polyether-26, 1, 2-hexanediol and 1, 2-pentanediol, and uniformly mixing and stirring. As phase B;
and thirdly, pumping the A, B phase into an emulsifying cylinder for homogenizing for 3-8 minutes, and stirring and dispersing uniformly. Preserving the heat for 10 minutes and beginning to cool;
dissolving citric acid, sodium citrate, sodium sulfite, ascorbyl glucoside, nicotinamide, arginine and dipotassium glycyrrhizinate in deionized water, and dispersing; as phase C;
and (V) when the temperature is reduced to 35-40 ℃, sequentially adding the prepared C phase, trehalose, yeast extract, the membrane-covered yeast fermentation product filtrate, essence, PEG-40 hydrogenated castor oil, phenoxyethanol and chlorphenesin. Stirring and dispersing uniformly to obtain the product.
The application test of the invention is as follows:
the tester: a plurality of healthy volunteers with age of 18-50 years and no history of skin diseases and allergy are selected.
Testing an instrument: facial Image analysis System VISIA-CR (Canfield corporation, USA) and Image processing enhancement analysis System Image-
Plus。
And (3) testing conditions are as follows: washing face with clear water at room temperature of 22 + -2 deg.C for 1 h, and shooting with VISIA.
The using method comprises the following steps: after bathing for 7 days continuously in the evening, the mask is applied for 15 minutes, and the skin is washed and cleaned in the morning of the next day. During the daytime, the sunshade umbrella is supported when going out on sunny days.
The test method comprises the following steps: the subjects were photographed with VISIA in front of and behind example 1 for 7 consecutive days. The effect indexes are as follows: comparative analysis Using the photographs before and after the use, the skin brightness (change in L value of the whole face) and the change in local wrinkles were measured, and the local skin spots were quantitatively analyzed.
One example of the data of the testers is extracted to analyze the skin brightness (change of the L value of the whole face brightness) and the change of local wrinkles, and the quantitative analysis of local skin spots is carried out. The change result of the full-face brightness L value is shown in FIG. 1, and the effect is shown in a visual chart, as shown in FIG. 4.
The change of local wrinkles is shown in fig. 2, and the wrinkle area and effect are visualized as shown in fig. 5.
Quantitative analysis of local skin spots, as shown in figure 3,
regions before and after quantitative analysis. As shown in figure 6, the contrast effect of the brown spots is visualized as shown in figure 7.
The results of full-face brightness analysis and comparison analysis of local wrinkles and local color spots show that the whitening and skin-brightening composition has the effects of lightening spots, removing yellow, improving skin brightness and reducing wrinkles; in addition, the visual image shot by VISIA is observed, so that the whitening and skin-brightening composition also has the function of improving the fineness and glossiness of the skin.
The above-mentioned embodiments are only for illustrating the technical solutions of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (14)
1. A cosmetic composition with skin whitening and brightening effects comprises effective amounts of nicotinamide, ascorbyl glucoside, hydrolyzed glycosaminoglycan, kakakadu plum extract, and yeast extract;
the weight percentages of the components are as follows:
1 to 4 percent of nicotinamide, 0.1 to 1 percent of ascorbyl glucoside,
0.01-0.5% of hydrolyzed aminodextran, 0.1-2% of kakadu plum extract,
yeast extract 0.1-10%, and cosmetic matrix 82.5-98.69%;
the sum of the weight percentages of all the components is 100 percent;
the cosmetic base consists of the following components:
50-90% of deionized water, 5-20% of humectant,
0.05 to 5 percent of thickening agent, 0.1 to 20 percent of emollient,
0.5 to 5 percent of emulsifier, 0.01 to 10 percent of skin conditioner,
0.01 to 0.5 percent of chelating agent, 0.001 to 1 percent of essence,
0.01 to 1 percent of preservative;
the skin conditioning agent in the cosmetic matrix is dipotassium glycyrrhizinate and allantoin.
2. The cosmetic composition with skin whitening and brightening effects of claim 1, wherein the yeast extract comprises one or more of yeast fermentation product filtrate, yeast lysate.
3. The cosmetic composition with whitening and skin-brightening effects according to claim 1, wherein the yeast extract comprises one or more of yeast fermentation product, yeast lysate extract.
4. The cosmetic composition with whitening and skin-brightening effects according to claim 1, wherein the yeast extract comprises a filtrate of fermentation product of tectorial yeast.
5. The cosmetic composition with the effects of whitening and brightening the skin as claimed in claim 1, wherein the moisturizing agent in the cosmetic matrix selected by the composition comprises one or more of glycerin, propylene glycol, dipropylene glycol, butylene glycol, 1, 2-hexanediol, 1, 2-pentanediol, corn gluten amino acids, caprylyl glycol, ethylhexylglycerin, sorbitol, β -glucan, saccharide isomers, diglycerol, polyethylene glycol-32, biogel-1, betaine, trehalose, sodium polyglutamate and sodium hyaluronate.
6. The cosmetic composition with skin whitening and brightening effects of claim 1, wherein the thickening agent in the cosmetic base selected for the composition comprises at least one of xanthan gum, arabic gum, carbomer, polyacrylate crosspolymer-6, ammonium acryloyldimethyltaurate/VP copolymer, acrylic acid/C10-30 alkanol acrylate crosspolymer, sodium polyacrylate, ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer, gellan gum, sodium acrylate copolymer, sodium polyacryl dimethyltaurate, polyvinylpyrrolidone, tara gum, and sclerotium rolfsii gum.
7. The cosmetic composition with whitening and skin-brightening effects according to claim 1, wherein the emollient in the cosmetic matrix selected from the composition comprises one or more of vegetable oil, synthetic oil, and mineral oil.
8. The cosmetic composition with the effects of whitening and brightening the skin as claimed in claim 1, wherein the emulsifier in the cosmetic base selected by the composition comprises one or more of PEG-20 methyl glucose sesquistearate, lecithin derivatives, glycerol stearate, polyoxyethylene fatty acid ester, polyglycerol fatty acid ester, polysorbate, sucrose fatty acid ester, sorbitan fatty acid ester and alkyl glucoside.
9. The cosmetic composition with the effects of whitening and brightening the skin as claimed in claim 1, wherein the emulsifier in the cosmetic base selected by the composition comprises one or more of PEG-20 methyl glucose sesquistearate, methyl glucoside sesquistearate, lecithin derivatives, glyceryl stearate, polyoxyethylene fatty acid ester, polyglycerol fatty acid ester, polysorbate, sucrose fatty acid ester and sorbitan fatty acid ester.
10. The cosmetic composition with whitening and skin-brightening effects of claim 1, wherein the chelating agent in the cosmetic base selected for the composition is one of EDTA-2Na and EDTA-4 Na.
11. The cosmetic composition with skin whitening and brightening effects of claim 1, wherein the preservative in the cosmetic base selected for the composition comprises one or more of parabens, phenoxyethanol, chlorphenesin, sodium benzoate, potassium sorbate, phenethyl alcohol and p-hydroxyacetophenone.
12. The cosmetic composition with skin whitening and brightening effects of claim 1, wherein the composition further comprises one or more of a photo-protecting agent, an antioxidant and a pH adjusting agent in a cosmetic base.
13. A cosmetic for whitening and brightening skin, comprising the cosmetic composition having whitening and brightening effects according to any one of claims 1 to 12.
14. The cosmetic according to claim 13, wherein the cosmetic is a cream, lotion, essence, skin-care gel, lotion or pack.
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| CN110115704B (en) * | 2019-05-29 | 2021-11-02 | 湖南美媛本草生物工程有限公司 | Enzyme composition and application thereof in cosmetics with whitening function |
| CN110101586B (en) * | 2019-05-29 | 2020-11-13 | 湖南美媛本草生物工程有限公司 | Nourishing, tightening and whitening mask paste and preparation method thereof |
| CN110522700A (en) * | 2019-10-16 | 2019-12-03 | 广州优敏泉生物科技有限公司 | The whitening cosmetic compound of anti-saccharification and anti-saccharification skin-lightening cosmetic containing it |
| CN110787086A (en) * | 2019-11-26 | 2020-02-14 | 广州市胜梅化妆品有限公司 | Composition for whitening skin and removing freckles and preparation method thereof |
| CN115337226B (en) * | 2022-08-22 | 2024-02-23 | 广州雅纯化妆品制造有限公司 | Whitening composition, cosmetic and preparation method thereof |
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