CN109528582A - A kind of skin care compositions containing black extract of willow bark - Google Patents
A kind of skin care compositions containing black extract of willow bark Download PDFInfo
- Publication number
- CN109528582A CN109528582A CN201811504380.7A CN201811504380A CN109528582A CN 109528582 A CN109528582 A CN 109528582A CN 201811504380 A CN201811504380 A CN 201811504380A CN 109528582 A CN109528582 A CN 109528582A
- Authority
- CN
- China
- Prior art keywords
- willow bark
- skin
- care compositions
- skin care
- containing black
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to cosmetic fields, and disclose a kind of skin care compositions containing black extract of willow bark, including following mass percent component: black willow bark shifts to an earlier date object 0.1-30%；Moisturizer 0.1-20%；Thickener 0.01-3%；Grease 0.1-20%；Emulsifier 0.1-5%；Functional additive 0.01-10%；Surplus is pure water.Can effectively cutin-softening, help falling off for aging cutin, clean skin effectively helps the coarse pore of skin repair, and skin is allowed to become more water profit, young, health.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of skin care compositions containing black extract of willow bark.
Background technique
With the development of society, the quickening of urban life rhythm, the busy and diet that human habitat is deteriorated, works
The unbalanced, influence factors such as daily life system is irregular, often can make body metabolism speed slow down, and abnormal metabolism
So that horn cell is not fallen off naturally, be thickly deposited in surface, pachylosis, obscure, serious person is caused to there is also skin
The symptoms such as inflammation, long acne.The skin aging problem occurred as soon as in face of young people so that it is natural mild, can effectively exfoliating be simultaneously
It repairs skin barrier, restore the favor that the young honorable cosmetics of skin increasingly obtain consumer, mild exfoliating skin care item
Market is also more and more fiery.
The main component of black willow bark is salicylic acid, and salicylic acid can help to remove the hair follicle of blocking, prevents pore from blocking, in advance
Anti-acne, salicylic acid can also penetrate into pore deep layer along sebaceous glands, and the cutin of dissolution pore accumulation promotes cutin to peel off same
When promote cell turnover, restore skin youth form.This natural plants extract of willow bark, while being also a kind of natural disappear
Scorching medicine, skin that is coarse for pore, being easy fuel-displaced long acne have good anti-inflammatory, cleaning action.
In the prior art, common exfoliating product is broadly divided into two major classes, and one kind is to utilize natural or synthetic mill
Sand particle reaches exfoliating effect by massage rubbing, it is this by material-flow method remove the extra cutin of skin have it is certain
Effect, but due to rubbing action, it is easy to lead to excessive exfoliating, be that cuticula is thinning, skin is made to become sensitive.It is another
Major class is tartaric acid exfoliating, and this kind of product pH is relatively low, often has stronger irritation.The present invention passes through microwave extract method
It extracts black willow bark essence to be added in skin-protection product, is acted on, connect by the effective substance salicylic acid that black willow bark skims the cream off milk
Under the conditions of nearly human skin pH, can effective cutin-softening, help falling off for aging cutin, penetrating skin adjusts water and oil balance, solution
A series of certainly skin problems such as dim heavy and color spot of the colour of skin, help skin active defense confrontation outside contamination and stimulation, and skin is evolved
Soft and smooth health, the perfect beautiful state of health is presented.
Summary of the invention
The present invention is added in conditioning essence cream by the black extract of willow bark that Microwave Extraction technique is extracted, and is really achieved
Mild exfoliating, the workable exfoliating product of sensitive skin person.Mild bigcatkin willow sour component in black extract of willow bark,
Can effectively cutin-softening, help falling off for aging cutin, clean skin effectively helps the coarse pore of skin repair, allows skin
Become more water profit, young, health.
Technical scheme is as follows:
A kind of skin care compositions containing black extract of willow bark, including following mass percent component:
Black willow bark shifts to an earlier date object 0.1-30%；
Moisturizer 0.1-20%；
Thickener 0.01-3%；
Grease 0.1-20%；
Emulsifier 0.1-5%；
Functional additive 0.01-10%；
Surplus is pure water.
Further, moisturizer include 1,3 butanediols, it is 1,3 propylene glycol, glycerol, glycine betaine, xylitol moisturizer, transparent
At least one of matter acid sodium, honey natural moisturizing factor.It is preferred that natural glycerol and 1,3 butanediols, xylitol moisturizing
The reasonably combined use of the factor.Xylitol moisturizer is the 100% natural compound compound of carbohydrate, and the moisture absorption of hydroxyl is rich in containing 2 kinds
Property molecule, can lock and capture hydrone, cuticula can be made to restore complete, protect the function of skin barrier.Meanwhile xylose
Alcohol moisturizer can make corium maintain optimal moisturizing degree (moisture content: 70%), and promoting the synthesis of corium hyaluronic acid, from
And increase the moisture deposit of corium.Xylitol moisturizer is compounded with glycerol, splendid moistening effect can be obtained, improves glycerol band
The not persistence of the sticky sense and moisturizing power that come.
Further, thickener includes carbomer, hydroxyethyl cellulose, xanthan gum, hydroxy ethyl methacrylate/acryloyl two
In N-methyltaurine sodium copolymer, polyacrylamide/C13-14 isoparaffin/polyoxyethylene lauryl ether, Sodium Polyacrylate
It is at least one.It is preferred that xanthan gum and hydroxy ethyl methacrylate/sodium acryloyldimethyl taurate copolymers.
Further, grease includes that dimethicone, dimethyl silicone polymer, dimethiconol, palmitinic acid are different
Propyl ester, jojoba oil, synthesis saualane, the different nonyl rouge of isononanoic acid, cetanol ethylhexoate, vaseline, in shea butter at least
It is a kind of.It is preferred that cetanol ethylhexoate, jojoba oil and dimethyl silicone polymer and the reasonable of dimethiconol are taken
Match.He Heba is a kind of desert plant, the oil in seed that this shrub plant for having a people Duo Gao is tied, and has good infiltration
Permeability also has speciality resistant to high temperature.The chemical molecular arrangement of Jojoba Oil is very similar with the sebum of the mankind, is easy in quilt
Skin and absorption.Jojoba Oil also contains abundant vitamin D and protein, is good moist and moisturizing oil, can safeguard
Moisture of skin, pre- anti-wrinkle and softening skin are suitble to mature and aging skin, are usually used in face, body massage and hair
Maintenance.
Further, emulsifier includes tristerin, PEG-100 stearate, olive oil spermaceti alcohol ester and sorb
Smooth olive oleate, hydrogenation lecithin, cetyl glucoside, ceteareth -20, in cetyl phosphate potassium extremely
Few one kind.It is preferred that hydrogenation lecithin.Hydrolecithin is extracted from soybean, includes the phosphatidyl choline of 25%-30%,
It is a kind of naturally occurring emulsifying agent with anti-inflammatory effect.It can effectively reduce stimulation, reduce the potential of other surfaces activating agent
Irritation, and the antiphlogistic effects of enhancing oil-soluble active object.Phosphatide is widely distributed in animals and plants, is the important of biological cell
Component part, it is to metabolism, and film infiltration plays very important effect, thus moisture-keeping function is splendid, can improve stemness skin
Skin strengthens the protection function of skin, promotes absorption of the skin to effective component, emulsifies simultaneously, solubilized, the tune of plasmalogen
System.
Further, functional additive includes that Co-Q10, tocopherol acetate, rose hip oil, phytosterol, β-Portugal are poly-
At least one of sugar, dipotassium glycyrrhizinate, collagen peptide, Argireline, vitamin V B3, bisabolol.It is preferred that dimension life
Plain VB3, dipotassium glycyrrhizinate and collagen peptide.The molecular weight of collagen peptide is 1000 or so, and can penetrate to the skin epidermis depth
Layer improves skin to moisturizing and elasticity to improve by promoting hyaluronic acid and collagen to synthesis.
A kind of preparation method of black extract of willow bark, includes the following steps:
A. black willow bark is cleaned up, is dried, by high energy shear milling at powdered；
B. powder obtained by a step is placed in reaction unit, 80% volume fraction ethyl alcohol of addition, 50 DEG C, ultrasonic extraction 30-50
Min takes filter residue after filtering, filter residue is placed in reaction unit, 80% volume fraction ethyl alcohol of addition, and 50 DEG C, ultrasonic extraction 30-50
Min merges the filtrate obtained twice after filtering；
C. the resulting filtrate of b step is flow to through external circulating device through decoloration device, active carbon built in decoloration device, circulation decoloration
20-30min obtains preliminary extracting solution；
D. the preliminary extracting solution that step c obtains is carried out that the 5-8% for arriving original volume is concentrated under reduced pressure, 10-12h is stood, in 4000r/
30min is centrifuged under the conditions of min；
E. it collects and is centrifuged gained sediment, vacuum drying obtains solids extraction object finished product.
1, the present invention extracts the effective substance of black willow bark by Microwave Extraction technique, by mild microwave extract method,
Avoid because extracting method it is improper due to destroy effective active composition in black willow bark, can effectively save extract
Effective active, environmental protection and energy saving, and higher recovery rate can be obtained.
2, the main component of black willow bark is salicylic acid, and salicylic acid can help to remove the hair follicle of blocking, prevents pore from blocking,
Pre- anti-acne, salicylic acid can also penetrate into pore deep layer along sebaceous glands, and the cutin of dissolution pore accumulation blocks acne to form contracting
Small pore, cutin-softening promote cutin to peel off while promoting cell turnover, restore skin youth form.
3, black extract of willow bark is applied in skin-protection product, by reasonably combined with other components, reaches a kind of
The exfoliating product for being applicable to sensitive skin and using as mild as a dove.Black extract of willow bark because of its main component salicylic acid,
The effect of itself can playing cutin-softening in the product, cutin is promoted to peel off.And the present invention is also excellent through a large number of experiments
The extremely excellent matched combined of effect is selected, product can be made in the condition close to human skin pH, be not required to the feelings of addition frosted particle
There is good exfoliation under condition.Simultaneously under the optimum organization of moisturizer, moisturizing grease, emulsifier and functional additive,
So that product not only has the effect of exfoliating, while there is moisturizing, repair skin, the barrier function for keeping skin and other effects.
Specific embodiment
Below in conjunction with specific embodiment, present invention is further described in detail.
Embodiment 1-4 and comparative example 1-3 composition such as following table, comparative example 4 is conventional commercial product, unlisted.
The preparation method of the black extract of willow bark of embodiment 1-4 and comparative example 1-3, includes the following steps:
A. black willow bark is cleaned up, is dried, by high energy shear milling at powdered；
B. powder obtained by a step is placed in reaction unit, 80% volume fraction ethyl alcohol of addition, 50 DEG C, ultrasonic extraction 30-50
Min takes filter residue after filtering, filter residue is placed in reaction unit, 80% volume fraction ethyl alcohol of addition, and 50 DEG C, ultrasonic extraction 30-50
Min merges the filtrate obtained twice after filtering；
C. the resulting filtrate of b step is flow to through external circulating device through decoloration device, active carbon built in decoloration device, circulation decoloration
20-30min obtains preliminary extracting solution；
D. the preliminary extracting solution that step c obtains is carried out that the 5-8% for arriving original volume is concentrated under reduced pressure, 10-12h is stood, in 4000r/
30min is centrifuged under the conditions of min；
E. it collects and is centrifuged gained sediment, vacuum drying obtains solids extraction object finished product.
Table 1: the formula of embodiment and comparative example
The effect of to above-mentioned 9 compositions, carries out instrument efficacy assessment, two methods of human body evaluation carry out efficacy assessment,
360 volunteers arbitrarily are selected, after entering group, every group is 40 volunteers, finally obtains and averagely ties as shown in table 2
Fruit.
Table 2: the effect of embodiment and comparative example, assesses test result
50 volunteers are convened, points 5 groups, every group of 10 people carry out patch test to above 8 compositions, (10 in spot tester
Slot), 5 slots are not added sample and do blank area, and in addition 5 dropwise addition samples, are attached to volunteer's inner forearm.Spot tester is removed after 7 h,
Test position dermoreaction is observed after 30min, is judged skin irritatin grade, is averaged.
Table 3: the patch test result of embodiment and comparative example
By the above test data, it is found that embodiment 1-4 is used, present composition raw material are formed and configuration proportion is prepared into
The exfoliating composition arrived has synergistic function between raw material, compared to for comparative example, has better exfoliating function
Effect, while moisturizing, enhancing skin elasticity can be obtained, improve skin shine and other effects.Comparative example 1 is used with comparative example 3
Lower dosage or the black extract of willow bark not added, and selected tartaric acid as exfoliating component, subject's shows as
Skin smoothness is lower, that is to say, that exfoliating effect is good, but its patch test effect is undesirable, and discovery has test
Be positive case.Although comparative example 2 is added to a certain amount of black extract of willow bark, the collocation of other compositions facilitates reduction
Moisturizing is with functional component, thus show as exfoliating effect general, moisturizing, skin elasticity and the skin shine of subject
It is poor.Comparative example 4 is the preferable exfoliating product of sales volume bought on the market, and it is general to show as exfoliation, angle
Be averaged gaining rate, skin elasticity and skin shine of matter layer moisture content gaining rate, water loss is undesirable.
Although description of this invention combination embodiments above carries out, those skilled in the art
Member can carry out many replacements based on the above contents, modifications and variations, be obvious.Therefore, all such substitutions,
Improvements and changes are included in the spirit and scope of appended claims.
Claims (7)
1. a kind of skin care compositions containing black extract of willow bark, which is characterized in that including following mass percent component:
Black willow bark shifts to an earlier date object 0.1-30%；
Moisturizer 0.1-20%；
Thickener 0.01-3%；
Grease 0.1-20%；
Emulsifier 0.1-5%；
Functional additive 0.01-10%；
Surplus is pure water.
2. the skin care compositions according to claim 1 containing black extract of willow bark, which is characterized in that the moisturizer
Including 1,3 butanediol, 1,3 propylene glycol, glycerol, glycine betaine, xylitol moisturizer, Sodium Hyaluronate, honey natural moisturizing factor
At least one of.
3. the skin care compositions according to claim 1 containing black extract of willow bark, which is characterized in that the thickener
Including carbomer, hydroxyethyl cellulose, xanthan gum, hydroxy ethyl methacrylate/sodium acryloyldimethyl taurate copolymers, poly- third
At least one of acrylamide/C13-14 isoparaffin/polyoxyethylene lauryl ether, Sodium Polyacrylate.
4. the skin care compositions according to claim 1 containing black extract of willow bark, which is characterized in that the grease packet
Include dimethicone, dimethyl silicone polymer, dimethiconol, isopropyl palmitate, jojoba oil, synthesis spiny dogfish
The different nonyl rouge of alkane, isononanoic acid, cetanol ethylhexoate, vaseline, at least one of shea butter.
5. the skin care compositions according to claim 1 containing black extract of willow bark, which is characterized in that the emulsifier
Including tristerin, PEG-100 stearate, olive oil spermaceti alcohol ester and the smooth olive oleate of sorb, hydrogenation lecithin,
At least one of cetyl glucoside, ceteareth -20, cetyl phosphate potassium.
6. the skin care compositions according to claim 1 containing black extract of willow bark, which is characterized in that described effect adds
Adding agent includes Co-Q10, tocopherol acetate, rose hip oil, phytosterol, beta glucan, dipotassium glycyrrhizinate, collagen
At least one of peptide, Argireline, vitamin V B3, bisabolol.
7. a kind of preparation method of black extract of willow bark as claimed in any one of claims 1 to 6, which is characterized in that including such as
Lower step:
A. black willow bark is cleaned up, is dried, by high energy shear milling at powdered；
B. powder obtained by a step is placed in reaction unit, 80% volume fraction ethyl alcohol of addition, 50 DEG C, ultrasonic extraction 30-50
Min takes filter residue after filtering, filter residue is placed in reaction unit, 80% volume fraction ethyl alcohol of addition, and 50 DEG C, ultrasonic extraction 30-50
Min merges the filtrate obtained twice after filtering；
C. the resulting filtrate of b step is flow to through external circulating device through decoloration device, active carbon built in decoloration device, circulation decoloration
20-30min obtains preliminary extracting solution；
D. the preliminary extracting solution that step c obtains is carried out that the 5-8% for arriving original volume is concentrated under reduced pressure, 10-12h is stood, in 4000r/
30min is centrifuged under the conditions of min；
E. it collects and is centrifuged gained sediment, vacuum drying obtains solids extraction object finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811504380.7A CN109528582A (en) | 2018-12-10 | 2018-12-10 | A kind of skin care compositions containing black extract of willow bark |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811504380.7A CN109528582A (en) | 2018-12-10 | 2018-12-10 | A kind of skin care compositions containing black extract of willow bark |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109528582A true CN109528582A (en) | 2019-03-29 |
Family
ID=65853349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811504380.7A Pending CN109528582A (en) | 2018-12-10 | 2018-12-10 | A kind of skin care compositions containing black extract of willow bark |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109528582A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110090182A (en) * | 2019-04-18 | 2019-08-06 | 保利沃利科技(武汉)有限公司 | A kind of mild bath oil and preparation method thereof |
| CN110169935A (en) * | 2019-05-29 | 2019-08-27 | 广东科盈科技有限公司 | A kind of compound for pore refining and preparation method thereof, application |
| CN112315883A (en) * | 2020-11-24 | 2021-02-05 | 哈尔滨敷尔佳科技发展有限公司 | Skin care composition for controlling oil and removing acne and preparation and application thereof |
| CN115177565A (en) * | 2022-07-27 | 2022-10-14 | 广州环亚化妆品科技股份有限公司 | Whitening and skin-brightening composition and application thereof in cosmetics |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003335657A (en) * | 2002-05-16 | 2003-11-25 | Noevir Co Ltd | Skin care preparation for external use |
-
2018
- 2018-12-10 CN CN201811504380.7A patent/CN109528582A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003335657A (en) * | 2002-05-16 | 2003-11-25 | Noevir Co Ltd | Skin care preparation for external use |
Non-Patent Citations (4)
| Title |
|---|
| D. SCHOLZ ET AL: "Comparison of Spectrum of Activity between Salicylic Acid and Naturally occurring Salicylates from Salix nigra.", 《JOURNAL OF INVESTIGATIVE DERMATOLOGY》 * |
| Y: "Atom美---艾多美去角质凝胶 Atomy Peeling Gel", 《COSDNA》 * |
| 张雷红等: "《天然药物化学》", 31 January 2017, 中国医药科技出版社 * |
| 熊方武等: "《中国临床药物大辞典 化学药卷》", 31 August 2018, 中国医药科技出版社 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110090182A (en) * | 2019-04-18 | 2019-08-06 | 保利沃利科技(武汉)有限公司 | A kind of mild bath oil and preparation method thereof |
| CN110169935A (en) * | 2019-05-29 | 2019-08-27 | 广东科盈科技有限公司 | A kind of compound for pore refining and preparation method thereof, application |
| CN112315883A (en) * | 2020-11-24 | 2021-02-05 | 哈尔滨敷尔佳科技发展有限公司 | Skin care composition for controlling oil and removing acne and preparation and application thereof |
| CN112315883B (en) * | 2020-11-24 | 2023-01-06 | 哈尔滨敷尔佳科技股份有限公司 | Skin care composition for controlling oil and removing acne and preparation and application thereof |
| CN115177565A (en) * | 2022-07-27 | 2022-10-14 | 广州环亚化妆品科技股份有限公司 | Whitening and skin-brightening composition and application thereof in cosmetics |
| CN115177565B (en) * | 2022-07-27 | 2023-09-26 | 广州环亚化妆品科技股份有限公司 | Whitening and skin brightening composition and application thereof in cosmetics |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109528582A (en) | A kind of skin care compositions containing black extract of willow bark | |
| JP3053368B2 (en) | Cosmetic and method for producing the same | |
| US20100323040A1 (en) | Cosmetic composition for topical use comprising wasabi | |
| CN105342943B (en) | A kind of condensation and preparation method thereof containing Chinese herbal medicine extract | |
| CN109172452B (en) | Compound extract of white paeony root and sophora flower and application of compound extract as cosmetic additive | |
| JP2004346045A (en) | Cosmetic additive, bathing agent and health food containing sake lees extract obtained in brewing of sake using deep seawater | |
| CN113842342A (en) | Plant dandruff-removing and itching-relieving agent as well as preparation method and application thereof | |
| CN108451818A (en) | A kind of elm bark extracting solution and its preparation method and application | |
| KR20210040522A (en) | Cosmetic composition, cosmetic mask pack comprisint the same and preperation method of the cosmetic composition | |
| WO1994002118A1 (en) | Skin regenerating cosmetic composition | |
| JP2004189644A (en) | Cosmetic | |
| CN106727255B (en) | Shampoo containing natural surfactant and preparation method thereof | |
| KR102247589B1 (en) | Cosmetic composition for improving skin comprising the moluccella laevis extraction and the hololeion maximowiczii Kitam. extraction as an effective ingredient | |
| US20190201320A1 (en) | Method for increasing lipolysis using a composition comprising bioactive nelumbo nucifera (lotus) extract | |
| JPH09291013A (en) | Skin cosmetic material | |
| KR102162377B1 (en) | Extracts derived from natural products and cosmetic composition containing the same, and process for producing the same | |
| KR102196414B1 (en) | A cometic composition comprising a mineral derived from lichens and galactomyces complex fermentation product | |
| KR102229259B1 (en) | Cosmetic Composition Containing Plumcot Extract | |
| JP4716497B2 (en) | External preparation for skin and hyaluronidase inhibitor | |
| CN109091440B (en) | Preparation method of compound plant extract and application of compound plant extract as SOD cosmetic additive | |
| JPS5913709A (en) | Moisturizer | |
| JP6723979B2 (en) | Wrinkle improver | |
| JP2004149424A (en) | Cosmetic and method for improving humectant function of cosmetic | |
| KR102481125B1 (en) | A composition for skin anti-pollution containing a daughter-in-law navel extract | |
| KR20050066331A (en) | Cosmetic composition comprising plant extract having moisturizing and anti-irritating activity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190329 |