CN109507438A - A kind of linear incubation slot and its automatic clinical chemistry analyzer - Google Patents

A kind of linear incubation slot and its automatic clinical chemistry analyzer Download PDF

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Publication number
CN109507438A
CN109507438A CN201811326054.1A CN201811326054A CN109507438A CN 109507438 A CN109507438 A CN 109507438A CN 201811326054 A CN201811326054 A CN 201811326054A CN 109507438 A CN109507438 A CN 109507438A
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China
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cup holder
probe
groove body
incubated
sample
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Granted
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CN201811326054.1A
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CN109507438B (en
Inventor
秦正贵
王心悦
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Dirui Medical Technology Co Ltd
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Dirui Medical Technology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a kind of linear incubation slot and its automatic clinical chemistry analyzers, including the cup holder driving assembly for being incubated for groove body, the intracorporal reaction cup holder of incubation slot being arranged in and translates for drive response cup holder, are provided with filler port on the incubation groove body;The two sides for being incubated for groove body are respectively arranged with loophole, the optical detection unit for being detected to sample in reaction vessel is provided on the outside of the loophole, achieve the purpose that removal tradition is incubated for disk disc type mechanism and for the mixing mechanism to liquid blending in reaction cup, reduce instrument size, reduce the structural complexity of instrument, while improving instrument global reliability, reduce costs.

Description

A kind of linear incubation slot and its automatic clinical chemistry analyzer
Technical field
The present invention relates to a kind of Medical Instruments, more specifically, it relates to a kind of linear incubation slot and its full-automatic life Change analyzer.
Background technique
With social economy and science and technology be constantly progressive, automatic clinical chemistry analyzer technology has obtained unprecedented hair Exhibition.Automatic clinical chemistry analyzer is also constantly general to small towns, community hospital at this stage not only in various medium-and-large-sized medical institutions And.
In the market, most of small towns, community hospital due to daily test sample amount it is less, mostly use semiautomatic biochemistry Analyzer, although such analyzer price is lower, test position there is usually one, and need add manually into test container It is loaded this and reagent, and is shaken up manually.It thus causes, adds the time point of sample and reagent into reaction cup every time It is mostly inconsistent, and the effect deviation mixed every time is also very big, has seriously affected the accuracy and consistency of test, thus A possibility that causing result to judge by accident is very big.This causes very big puzzlement, serious or even meeting for doctor's clinical judgment state of an illness Influence the sound life security of patient.
Under such environment, a kind of at low cost, high reliablity is researched and developed for small towns, the particularity of community hospital, innovation And automatic clinical chemistry analyzer small in size.
Therefore, the prior art could be improved and develop.
Summary of the invention
The object of the present invention is to provide a kind of linear incubation slot and its automatic clinical chemistry analyzers, reach removal tradition and incubate Yu Pan disc type mechanism and for the purpose to the mixing mechanism of liquid blending in reaction cup, reduces instrument size, reduces The structural complexity of instrument reduces costs while improving instrument global reliability.
Above-mentioned technical purpose of the invention has the technical scheme that
A kind of linear incubation slot, wherein including being incubated for groove body, being arranged in the intracorporal reaction cup holder of incubation slot and for driving The cup holder driving assembly of cup holder translation is reacted, is provided with filler port on the incubation groove body;The two sides difference for being incubated for groove body It is provided with loophole, the optical detection list for being detected to sample in reaction vessel is provided on the outside of the loophole Member.
The linear incubation slot, wherein the reaction cup holder is offered along its length for placing response container Reacting hole, it is described reaction cup holder two sides position corresponding with the reacting hole at be respectively arranged with light hole, the light passing The height and width in hole are adapted to the loophole of corresponding side, and loophole described in two sides is parallel and is arranged concentrically.
The linear incubation slot, wherein the cup holder driving assembly includes the cup for reacting cup holder described in support Frame fixing seat, the fixing seat lead screw for driving the cup holder fixing seat and it is parallel to lead screw setting and what is play the guiding role lead To bar;The both ends of the cup holder fixing seat are respectively arranged with spring column pin, and the both ends of the reaction cup holder bottom are respectively arranged with The positioning fixation hole being adapted to the spring column pin is provided with the guide groove for reaction cup holder insertion in the cup holder fixing seat.
The linear incubation slot, wherein the fixing seat lead screw is set in the incubation slot body, the fixing seat Lead screw is provided with the feed screw nut being adapted to fixing seat lead screw in the length direction setting for being incubated for groove body, the cup holder fixing seat And the linear bearing being adapted to guide rod.
The linear incubation slot, wherein the two sides for being incubated for groove body are respectively arranged with shaft fixinig plate, and described turn Straight pin is provided on axis fixinig plate, the incubation groove body front end is provided with insulation cover, and the insulation cover is rotationally connected with cylinder It sells, the baffle for limiting insulation cover rotational angle is provided on the shaft fixinig plate;Annular is offered on the insulation cover Slot, has been filled with sealing strip in the annular groove, the insulation cover and is incubated on groove body and is respectively arranged with compatible magnet.
A kind of as above described in any item automatic clinical chemistry analyzers, wherein including for carrying sample container and examination The sample reagent disk and probe mechanism of agent container;The probe mechanism is for rotating to sample container required in sample reagent disk Or the station of reagent container, it draws sample or reagent and fills into corresponding reaction vessel in incubation slot body, and reaction is held Liquid in device carries out compressing and mixing movement.
The automatic clinical chemistry analyzer, wherein optical detection unit is set to the bottom for being incubated for groove body, the optics Detection unit includes being set to be incubated for the frame body of groove body bottom, the lamp holder of frame body one end is arranged in and is arranged in the frame body other end Selective filter, the upper end of the selective filter is provided with photocell box, heat dissipation is provided with below the lamp holder Piece and the radiator fan for being connected to cooling fin.
The automatic clinical chemistry analyzer, wherein the probe mechanism includes that the rack for being incubated for groove body side is arranged in, It is provided with swing arm above the rack, splined shaft is provided between the rack and swing arm, the splined shaft is set to described One end of swing arm, the other end of the swing arm are provided with probe, are provided in the rack for driving the splined shaft to move Probe actuation component;The side of the probe mechanism is provided with the service sink for cleaning probe inside and outside wall.
The automatic clinical chemistry analyzer, wherein the probe actuation component includes the lifting electricity being set in rack Machine, the lifting guide pillar being adapted to the splined shaft are driven as the lifting motor and drive splined shaft described in by synchronous belt Sample or reagent are drawn in the mobile lifting driving pulley of lifting guide pillar, the lifting motor operation driving probe decline.
The automatic clinical chemistry analyzer, wherein the probe mechanism further include be set to frame upper end rotation it is fixed Position optocoupler, the rotational positioning optocoupler with corresponded to the position of compressing sample or reagent and for judging that the splined shaft revolves Indexing is set.
In conclusion passing through with the application of the invention, reaching removal tradition is incubated for disk disc type mechanism and for in reaction cup The purpose of the mixing mechanism of liquid blending, reduces instrument size, reduces the structural complexity of instrument, whole improving instrument While reliability, reduce costs.
Detailed description of the invention
Fig. 1 is the overall structure diagram of automatic clinical chemistry analyzer in the present embodiment.
Fig. 2 is the external structure schematic diagram of the present embodiment linear incubation slot.
Fig. 3 is the schematic diagram of internal structure of the present embodiment linear incubation slot.
Fig. 4 is the attachment structure schematic diagram that groove body and insulation cover are incubated in the present embodiment.
Fig. 5 is the structural schematic diagram of the present embodiment middle probe mechanism.
Fig. 6 is the structural schematic diagram of optical detection unit in the present embodiment.
In figure: 1, linear incubation slot;101, it is incubated for groove body;102, cup holder is reacted;103, cup holder fixing seat;104, fixed Seat lead screw;105, feed screw nut;106, lead screw driven pulley;107, lead screw driving pulley;108, driving motor;109, it is oriented to Bar;110, linear bearing;111, straight line positions optocoupler;112, code-disc;113, insulation cover;114, sealing strip;115, shaft is fixed Piece;116, filler port;117, reacting hole;118, light hole;119, loophole;2, optical detection unit;201, lamp holder;202, light Battery case;203, selective filter;204, cooling fin;205, radiator fan;3, probe mechanism;301, probe;302, spline Axis;303, active rotation belt wheel;304, rotating electric machine;305, rotational positioning optocoupler;306, lifting motor;307, main belt is gone up and down Wheel;308, lifting guide pillar;4, service sink.
Specific embodiment
Below in conjunction with attached drawing, invention is further described in detail.
This specific embodiment is only explanation of the invention, is not limitation of the present invention, those skilled in the art Member can according to need the modification that not creative contribution is made to the present embodiment after reading this specification, but as long as at this All by the protection of Patent Law in the scope of the claims of invention.
Embodiment: the embodiment of the present invention provides a kind of linear incubation slot, as shown in Figure 1 to Figure 3, including is incubated for groove body 101, the reaction cup holder 102 being incubated in groove body 101 and the cup holder driving group mobile for drive response cup holder 102 are set Part, is provided with filler port 116 on the incubation groove body 101, the filler port 116 be set to 301 rotation round of probe with react The intersection of container straight-line trajectory or points of tangency.The two sides for being incubated for groove body 101 are respectively arranged with loophole 119, and two sides are saturating Unthreaded hole 119 is parallel and is arranged concentrically, and the outside of two loopholes 119 respectively corresponds optical detection unit 2 and perspective mirror assembly.
The reaction cup holder 102 linearly offers the reacting hole 117 for placing response container.The reaction cup 102 two sides of frame and 117 corresponding position of reacting hole are provided with light hole 118, the height of the light hole 118 and width with it is corresponding The loophole 119 of side is adapted to, to measure liquid absorbance in container when reaction vessel passes through optical detection unit.Specifically , the reaction vessel is reaction cup.
The cup holder driving assembly includes for reacting the cup holder fixing seat 103 of cup holder 102 described in support, for driving The guide rod 109 for stating the fixing seat lead screw 104 of cup holder fixing seat 103 and being parallel to lead screw setting and playing the guiding role.
The front end for being incubated for groove body 101 is provided with insulation cover 113, and the outer wall attaching for being incubated for groove body 101 is provided with The periphery of heating tape, the heating tape is pasted with heat-preservation cotton.
Specifically, the incubation groove body 101 is aluminum alloy material, there is good thermal conductivity, the incubation groove body 101 Outer wall is pasted with heating tape, and the periphery of the heating tape is pasted with heat-preservation cotton.
The both ends of the cup holder fixing seat 103 are respectively arranged with spring column pin, the both ends point of reaction 102 bottom of cup holder It is not provided with the positioning fixation hole being adapted to the spring column pin, is provided in the cup holder fixing seat 103 for reacting cup holder 102 The guide groove of insertion.
Specifically, the reaction cup holder 102 is fixed in the cup holder fixing seat 103, the both ends point of cup holder fixing seat 103 It is not provided with spring column pin, the both ends of reaction 102 bottom of cup holder are respectively arranged with the positioning being adapted to spring column pin and fix Hole, reaction cup holder 102 are inserted into cup holder fixing seat 103 by guide groove.It is fixed when reaction cup holder 102 is inserted into cup holder by guide groove When on seat 103, spring column pin is sunk to inside cup holder fixing seat 103, and after reacting cup holder 102 in place, spring column pin pop-up will be anti- It answers cup holder 102 and cup holder fixing seat 103 fixed, closes insulation cover 113 at this time.
Fixing seat lead screw 104 is provided in the incubation groove body 101, the fixing seat lead screw 104 is along incubation groove body 101 Length direction setting, be provided in the cup holder fixing seat 103 feed screw nut 105 being adapted to fixing seat lead screw 104 and with The linear bearing 110 that guide rod 109 is adapted to;The bottom of the cup holder fixing seat 103 is provided with code-disc 112 and straight line positioning light Coupling 111, the positioning for reaction vessel.
As shown in figure 4, the two sides for being incubated for groove body 101 are respectively arranged with shaft fixinig plate 115, the shaft fixinig plate Straight pin is provided on 115, the insulation cover 113 is rotationally connected with straight pin, is provided with and is used on the shaft fixinig plate 115 Limit the baffle of 113 rotational angle of insulation cover;Annular groove is offered on the insulation cover 113, is filled in the annular groove There is sealing strip 114;Compatible magnet is respectively arranged on the insulation cover 113 and incubation groove body 101.
Specifically, feed screw nut 105 and linear bearing 110 are provided in the cup holder fixing seat 103, the lead screw spiral shell Mother 105 is mobile to drive the synchronizing moving on guide rod 109 of linear bearing 110 on fixing seat lead screw 104.Fixing seat lead screw 104 one end is provided with lead screw driven pulley 106, and lead screw driven pulley 106 is connected to lead screw driving pulley by synchronous belt 107, lead screw driving pulley 107 is fixed on the output shaft of driving motor 108.The bottom of cup holder fixing seat 103 is provided with code-disc 112 And straight line positions optocoupler 111, the positioning for reaction vessel position.
Annular groove is offered on insulation cover 113, is filled with sealing strip 114 in annular groove, the upper end of insulation cover 113 is provided with Magnet is also equipped with magnet on the incubation groove body 101.When insulation cover 113 is closed, magnet is attracted, compression seal item 114, So that being incubated for groove body 101 keeps sealing, to guarantee the isoperibol being incubated in groove body 101.
The two sides for being incubated for groove body 101 are respectively arranged with shaft fixinig plate 115, fixinig plate 115 around the shaft of insulation cover 113 On straight pin rotation.When opening insulation cover 113 and going to horizontal position, the baffle on shaft fixinig plate 115 prevents heat preservation Lid 113 continues to rotate so that the maximum folding of insulation cover 113 is to horizontal position, thus the other elements that will not be collided on instrument.
The present invention also provides a kind of automatic clinical chemistry analyzers as described above, as shown in Figure 1, automatic clinical chemistry analyzer Include:
Linear incubation slot 1 drives the reaction vessel to carry out tandem movement, and mention for it for carrying reaction vessel For being incubated for environment;
Sample reagent disk, for carrying sample container and reagent container;
Optical detection unit 2, for carrying out photooptical data measurement to liquid in reaction vessel;
Specifically, the optical detection unit 2 is used to measure the absorbance of liquid in reaction vessel;
Probe mechanism 3 draws quantitative sample for rotating the position to sample container required in sample reagent disk or reagent container Or reagent and fill into reaction vessel corresponding in incubation slot, and in reaction vessel liquid carry out compressing mixing movement;
Service sink 4, for cleaning 301 inside and outside wall of probe;
The linear incubation slot 1, track and probe 301 where reaction vessel central line movement thereon are swung where circular arc Intersection of locus is tangent;Reaction vessel where intersection or points of tangency can be used as probe 301 and fill position.
As shown in figure 5, the probe mechanism 3 includes that the rack for being incubated for 101 side of groove body is arranged in, the top of the rack It is provided with swing arm, splined shaft 302 is provided between the rack and swing arm, the splined shaft 302 is set to the one of the swing arm End, the other end of the swing arm are provided with probe 301, are provided in the rack for driving the splined shaft 302 to move Probe actuation component;The side of the probe mechanism 3 is provided with the service sink 4 for cleaning 301 inside and outside wall of probe.
The probe mechanism 3 is set to the side of linear incubation slot 1, and its 301 rotation round of probe and reaction vessel Straight-line trajectory is tangent or intersects.
The liter that the probe actuation component includes the lifting motor 306 being set in rack, is adapted to the splined shaft 302 Drop guide rod 308 is driven by the lifting motor 306 and drives splined shaft 302 to move along the lifting guide pillar 308 by synchronous belt Lifting driving pulley 307, the lifting motor 306 operation driving decline of probe 301 draws sample or reagent.
The probe mechanism 3 further includes the rotational positioning optocoupler 305 for being set to frame upper end, the rotational positioning optocoupler 305 with corresponded to the position of compressing sample or reagent and for judging 302 rotation position of splined shaft.
Specifically, the probe 301 is fixed on the top of splined shaft 302, the driving of rotating electric machine 304 master by swing arm Dynamic rotation belt wheel 303 drives splined shaft 302 to rotate by synchronous belt, and rotational positioning optocoupler 305 judges that the splined shaft 302 rotates The position of position, rotational positioning optocoupler 305 and required absorption sample or reagent corresponds, so that probe 301 is by rotating to Above up to the container of required absorption sample or reagent.
The working principle of middle probe of embodiment of the present invention mechanism 3 is as follows:
Lifting motor driving lifting driving pulley drives splined shaft to move along lifting guide pillar by synchronous belt, and band probe swing arm rotates When above to the container of required absorption sample or reagent, sample or reagent are drawn in lifting motor operation driving probe decline.Probe After the completion of drawing sample or reagent, lifting motor operation, driving probe, which rises to, is detached from sample tube or reagent container mouth position, this When, rotating electric machine operation drives probe to be rocked to the filling hole site for being incubated for and opening up at the top of groove body, lifting motor operation, driving It pricks under probe into reaction vessel, sample or reagent is filled in reaction vessel.At this point, lifting motor drives probe to be detached from liquid Face, probe draw the air of predetermined amount, penetrate liquid level down again hereinafter, executing compressing mixing movement repeatedly, preferably twice.It is mixed After even, probe is detached from good fortune in groove body under the drive of lifting motor, drives backspin to go to service sink station in rotating electric machine, The cleaning for carrying out inside and outside wall, completes an action cycle of probe.
As shown in fig. 6, the optical detection unit 2 is set to the bottom for being incubated for groove body 101, the optical detection unit 2 It is incubated for the frame body of 101 bottom of groove body, the lamp holder 201 of frame body one end is set and the frame body other end is set including being set to Selective filter 203, the upper end of the selective filter 203 are provided with photocell box 202, the lower section of the lamp holder 201 It is provided with cooling fin 204 and is connected to the radiator fan 205 of cooling fin 204.
Specifically, optical detection unit 2 is used to carry out optical data measurement to reaction vessel, such as 8 tunnels selectivity is provided Optical filter 203 is parallel and is arranged side by side, while carrying out the detection of 8 wavelength.Linear motion is carried out in reaction vessel and from optics When Measurement channel passes through, optical detection unit 2 completes the photooptical data measurement of a reaction vessel specific wavelength.
The workflow of automatic clinical chemistry analyzer in the embodiment of the present invention are as follows:
Cup holder driving motor drives reaction cup holder to move to filling position, at this point, the reaction vessel of sample or reagent to be filled Positioned at the underface for being incubated for filler port on groove body.
Sample or reagent are drawn in the reaction vessel position that probe is rocked to sample or reagent to be drawn, and then return to incubation slot The underface of filler port on body, lifting motor operation drive and prick under probe into reaction vessel, sample or reagent are filled into anti- It answers in container.
At this point, probe is detached from liquid level under the drive of lifting motor, after drawing the air of predetermined amount, liquid level is penetrated down again Hereinafter, executing compressing mixing movement repeatedly, preferably twice.
After mixing, probe is detached under the drive of lifting motor is incubated for groove body, under the drive of rotating electric machine, rotation To washing station, i.e. service sink position, the cleaning of inside and outside wall is carried out.
Meanwhile cup holder driving motor drives reaction cup holder movement, and passes through from optical measurement channels, optical detection unit is complete It is measured at the optical data of each reaction vessel specific wavelength, then cup holder driving motor drives reaction cup holder to move to next anti- It answers container to fill station, continues the movement for filling sample or reagent and mixing, until reaction terminates.
Biochemical Analyzer of the embodiment of the present invention is by taking single reagent reacts as an example, and in each reaction duty cycle, probe has needed Filling, mixing and the cleaning of Cheng Yici sample and the filling of a reagent, mixing and cleaning.Meanwhile linear incubation slot Have and moves twice and carry out photooptical data measurement.
Existing Biochemical Analyzer by including at least probe, reaction cup and agitating paddle in the inner, filling and mixing every time After the completion, it requires to clean reaction cup, probe and agitating paddle, to prevent cross contamination, water consumption is very big, therefore right Be a kind of puzzlement for the area of part water shortage.Meanwhile semi-automatic biochemical analyzer is taken and manually adds sample and reagent Mode, there are biggish artificial bias factors, cause the sample size being added every time and amount of reagent to be all not necessarily the same, seriously The precision for reducing measured value affects the accuracy of test, very big puzzlement is caused to doctor's clinical judgment state of an illness, when serious It even will affect the life security of patient.
It is rotary-disk type structure that disk is incubated in conventional biochemical analyzer, and reaction cup is to be distributed in be incubated on disk periphery, is incubated It educates and contains rotate driving in disk, reaction cup is driven to do regular rotation, cooperate probe and the regular rotation of sample reagent disk, To complete the filling of sample and reagent, and the mixing by the rotation completion of mixing mechanism to liquid in reaction cup.
In the embodiment of the present invention, replaces conventional biochemical analyzer rotating disc type to be incubated for disk by using linear incubation slot, pass System is incubated among disk in addition to rotating mechanism, remaining region can not be utilized, and the size of thermostat is compared in tradition incubation disk Fixed incubation slot is bigger.While overall compact utilization space of the invention, overall structure is simplified, is reduced costs.
And the invention proposes probe compressing blending manners, are not necessarily to mixing mechanism, after probe has filled sample every time, immediately Compressing mixing movement is executed to liquid in current reaction vessel.After the completion of mixing, it is rocked to service sink and is cleaned, saved The water used to agitating paddle cleaning, saves cost needed for mixing mechanism in traditional analysis instrument each duty cycle.
In contrast, traditional agitating paddle is generally flat paddle agitating paddle, when being stirred to react liquid in container, reaction vessel Interior liquid condition forms laminar flow, from it is microcosmic liquid in reaction cup is divided into countless lamellas from the point of view of, each layer of liquid is all enclosing It is rotated around agitating paddle center, in the case where rotating speed of agitator is not high, the liquid on upper layer is difficult to diffuse into lower liquid, such as Fruit is wanted to reach ideal mixed effect, needs to put forward higher requirements the revolving speed of agitating paddle.
On the contrary, probe compressing blending manner, when liquid is when passing through the probe internal diameter of very small diameter in reaction cup, in probe Diameter is usually no more than 0.5mm, and liquid falls over each other to be squeezed into probe interior, and when liquid passes through probe tips aperture, liquid occurs Turbulent flow mixes it tentatively in probe.During liquid is spued from probe interior and enters reaction vessel, due to impact Power effect, when liquid enters in reaction vessel, is random motion, further mixes to liquid, fill to reach Divide the purpose mixed.
To sum up, in order to increase instrument reliability, cost is reduced, the size of instrument is reduced, the present invention proposes: including square groove type Incubation disk, the incubation disk of square groove type need to only be moved forward and backward without rotation.Reaction cup in the circular arc and incubation slot that probe is swung The intersection or tangent of central line motion profile.Reaction cup where intersection or points of tangency can be used as probe filling position;It is not necessarily to Mixing mechanism after probe has filled sample every time, executes compressing to liquid in current reaction cup immediately and mixes.It is completed wait mix Afterwards, it is rocked to service sink to be cleaned, saves water used to agitating paddle cleaning in traditional analysis instrument each duty cycle, section Cost needed for mixing mechanism is saved, and the ruler that conventional biochemical analyzer rotating disc type is incubated for disk is greatly reduced in linear incubation slot It is very little, reduce manufacturing cost.
By with the application of the invention, eliminating tradition is incubated for disk disc type mechanism and for mixing to liquid blending in reaction cup Even mechanism saves conventional biochemical instrument agitating paddle institute water consumption.Can great reduced equipment sizes, reduce the structure of analyzer Complexity while improving global reliability, reduces costs, also has the advantages that water-saving.
It should be understood that the application of the present invention is not limited to the above for those of ordinary skills can With improvement or transformation based on the above description, all these modifications and variations all should belong to the guarantor of appended claims of the present invention Protect range.

Claims (10)

1. a kind of linear incubation slot, it is characterized in that: including being incubated for groove body, being arranged in the intracorporal reaction cup holder of incubation slot and use Filler port is provided in the cup holder driving assembly of drive response cup holder translation, on the incubation groove body;It is described to be incubated for the two of groove body Side is respectively arranged with loophole, and the optics inspection for being detected to sample in reaction vessel is provided on the outside of the loophole Survey unit.
2. linear incubation slot according to claim 1, it is characterized in that: the reaction cup holder open up along its length it is useful It is respectively arranged at the reacting hole of placing response container, the two sides position corresponding with the reacting hole of the reaction cup holder logical Unthreaded hole, the height and width of the light hole are adapted to the loophole of corresponding side, and loophole described in two sides is parallel and same Heart setting.
3. linear incubation slot according to claim 1, it is characterized in that: the cup holder driving assembly includes being used for support institute State the reaction cup holder fixing seat of cup holder, the fixing seat lead screw for driving the cup holder fixing seat and be parallel to lead screw setting and The guide rod playing the guiding role;The both ends of the cup holder fixing seat are respectively arranged with spring column pin, the reaction cup holder bottom Both ends are respectively arranged with the positioning fixation hole being adapted to the spring column pin, are provided in the cup holder fixing seat for reacting cup holder The guide groove of insertion.
4. linear incubation slot according to claim 3, it is characterized in that: the fixing seat lead screw is set to the incubation slot In vivo, the fixing seat lead screw is provided with and fixing seat silk in the length direction setting for being incubated for groove body, the cup holder fixing seat The feed screw nut of thick stick adaptation and the linear bearing being adapted to guide rod.
5. linear incubation slot according to claim 1, it is characterized in that: the two sides for being incubated for groove body are respectively arranged with and turn Axis fixinig plate is provided with straight pin on the shaft fixinig plate, and the incubation groove body front end is provided with insulation cover, the insulation cover It is rotationally connected with straight pin, the baffle for limiting insulation cover rotational angle is provided on the shaft fixinig plate;The heat preservation It covers and offers annular groove, sealing strip has been filled in the annular groove, has been respectively set on the insulation cover and incubation groove body There is compatible magnet.
6. a kind of automatic clinical chemistry analyzer according to claim 1-5, it is characterized in that: including for carrying sample The sample reagent disk and probe mechanism of this container and reagent container;The probe mechanism is for rotating to sample reagent disk The station of required sample container or reagent container is drawn sample or reagent and is filled to corresponding reaction vessel in incubation slot body In, and compressing and mixing movement are carried out to the liquid in reaction vessel.
7. automatic clinical chemistry analyzer according to claim 6, it is characterized in that: optical detection unit is set to incubation groove body Bottom, the optical detection unit include be set to be incubated for groove body bottom frame body, be arranged in frame body one end lamp holder and The selective filter of the frame body other end is set, and the upper end of the selective filter is provided with photocell box, the lamp holder Lower section be provided with cooling fin and be connected to the radiator fan of cooling fin.
8. automatic clinical chemistry analyzer according to claim 6, it is characterized in that: the probe mechanism includes that setting is being incubated for The rack of groove body side is provided with swing arm above the rack, splined shaft, the flower is provided between the rack and swing arm Key axis is set to one end of the swing arm, and the other end of the swing arm is provided with probe, is provided in the rack for driving The probe actuation component of the splined shaft movement;The side of the probe mechanism is provided with the cleaning for cleaning probe inside and outside wall Pond.
9. automatic clinical chemistry analyzer according to claim 8, it is characterized in that: the probe actuation component includes being set to Lifting motor in rack, the lifting guide pillar being adapted to the splined shaft are driven by the lifting motor and by synchronous belt band Sample is drawn in the lifting driving pulley that dynamic splined shaft is moved along the lifting guide pillar, the lifting motor operation driving probe decline Or reagent.
10. automatic clinical chemistry analyzer according to claim 6, it is characterized in that: the probe mechanism further includes being set to The rotational positioning optocoupler of frame upper end, the rotational positioning optocoupler are corresponded and are used for the position to compressing sample or reagent Judge the splined shaft rotation position.
CN201811326054.1A 2018-11-08 2018-11-08 Linear incubation groove and full-automatic biochemical analyzer thereof Active CN109507438B (en)

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CN109507438B CN109507438B (en) 2022-06-14

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