CN210079376U - Reagent mixing mechanism, reagent storage device and chemiluminescence immunoassay appearance - Google Patents
Reagent mixing mechanism, reagent storage device and chemiluminescence immunoassay appearance Download PDFInfo
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- CN210079376U CN210079376U CN201920600625.XU CN201920600625U CN210079376U CN 210079376 U CN210079376 U CN 210079376U CN 201920600625 U CN201920600625 U CN 201920600625U CN 210079376 U CN210079376 U CN 210079376U
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Abstract
The utility model provides a reagent mixing mechanism for carry out the mixing to the reagent in the holding bottle, includes: the bottle blending device comprises a turntable and a blending assembly, wherein the blending assembly comprises a supporting unit and a blending unit, the supporting unit is rotatably arranged on the turntable, one end of the supporting unit is used for fixing a containing bottle, and the other end of the supporting unit is connected with the blending unit; and the driving assembly comprises a rotating shaft and a driving unit, the rotating shaft is fixedly connected with the turntable, and the driving unit is used for driving the rotating shaft to drive the turntable to rotate. The reagent mixing device has the beneficial effects of reducing the volume of a reagent mixing mechanism and finally realizing the requirements of simplicity, compactness and high efficiency.
Description
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a reagent mixing mechanism, reagent storage device and chemiluminescence immunoassay appearance.
Background
The full-automatic chemiluminescence immunoassay analyzer is equipment for analyzing by directly marking antigen and antibody with chemiluminescence reagent, can automatically complete a series of processes such as sampling, sample adding, reaction and detection, and the like, and reduces the manual operation error while improving the detection efficiency. The reagent storage device for storing and conveying the reagent is arranged on the full-automatic chemiluminescence immunoassay analyzer, and in order to ensure the accuracy of a test result, the reagent containing magnetic beads is generally required to be uniformly mixed so as to prevent the precipitation of the magnetic bead reagent from influencing the measurement result, and generally, the structure of the traditional reagent storage device is complex.
SUMMERY OF THE UTILITY MODEL
The utility model provides a technical problem how to ensure reagent mixing mechanism simple structure.
The utility model provides a reagent mixing mechanism for carry out the mixing to the reagent in the holding bottle, includes:
a rotating disk, a rotating disk and a rotating disk,
the blending assembly comprises a supporting unit and a blending unit, the supporting unit is rotatably arranged on the turntable, one end of the supporting unit is used for fixing a containing bottle, and the other end of the supporting unit is connected with the blending unit; and
the driving assembly comprises a rotating shaft and a driving unit, the rotating shaft is fixedly connected with the turntable, and the driving unit is used for driving the rotating shaft to drive the turntable to rotate;
when the rotary table rotates, the supporting unit and the containing bottle revolve around the rotary table, and meanwhile, the blending unit drives the supporting unit and the containing bottle to rotate to achieve reagent blending.
In one embodiment, the supporting unit comprises a connecting arm and a support, the turntable is provided with a through hole communicated with two opposite sides of the turntable, the connecting arm is rotatably arranged in the through hole, the support is arranged on the connecting arm and extends out of one side of the turntable to fixedly contain a bottle, and the blending unit is connected with the connecting arm and is positioned on the other side of the turntable.
In one embodiment, the blending unit comprises a first gear and a second gear, the first gear is sleeved on the rotating shaft and is in a static state, and the second gear is fixed on the supporting unit and can be meshed with the first gear; when the turntable rotates, the second gear rotates relative to the first gear to drive the supporting unit to rotate.
In one embodiment, the diameter of the first gear is smaller than the diameter of the turntable, and the first gear and the second gear are externally meshed.
In one embodiment, the driving unit includes a motor, a belt wheel and a transmission belt, the belt wheel is mounted on the rotating shaft, and the transmission belt is sleeved on the belt wheel and an output shaft of the motor.
In one embodiment, the rotary table further comprises a sleeve, the sleeve is enclosed into a containing cavity, and the rotary table is located in the containing cavity.
In one embodiment, the driving assembly further comprises a fixing plate, the sleeve is mounted on the fixing plate, and the driving unit is connected with the fixing plate.
In one embodiment, any one of the following is further included:
the rotary disc is provided with a plurality of wedge positions for matching with the reagent kit, and the wedge positions are arranged at intervals along the circumferential direction of the rotary disc;
a clamping groove is formed in the rotary disc and used for being matched with a buckle on the kit;
the rotating shaft is sleeved with a bearing, and the bearing is connected with the rotating disc.
A reagent storage device comprises a reagent kit, a containing bottle and any one of the reagent blending mechanisms, wherein the containing bottle is rotatably arranged in the reagent kit and is connected with a supporting unit.
A chemiluminescence immunoassay analyzer comprises a mechanical arm, a reagent needle and the reagent storage device, wherein the reagent needle is arranged on the mechanical arm and can suck a reagent in a containing bottle.
The utility model discloses a technical effect of an embodiment is: because the reagent mixing mechanism only comprises the turntable, the mixing component and the driving component, the rotating shaft of the driving component is connected with the turntable, and in the process that the rotating shaft drives the turntable to rotate, the containing bottle revolves around the rotating shaft, and meanwhile, the mixing component drives the containing bottle to rotate, so that the reagent in the containing bottle is mixed uniformly. Therefore, the reagent can be smoothly mixed without arranging other additional structures, the structure of the whole reagent mixing mechanism is simplified, the volume of the reagent mixing mechanism is reduced, and the requirements of simplicity, compactness and high efficiency are finally met.
Drawings
FIG. 1 is a schematic diagram of an overall assembly structure of a reagent mixing mechanism according to an embodiment;
FIG. 2 is a schematic partial perspective cross-sectional view of FIG. 1;
FIG. 3 is a schematic plan view in full section of FIG. 1;
fig. 4 is a schematic structural diagram of a chemiluminescence immunoassay analyzer provided in one embodiment.
Detailed Description
In order to facilitate understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. The preferred embodiments of the present invention are shown in the drawings. The invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "inner", "outer", "left", "right" and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Referring to fig. 1 to 4, the reagent storage device 20 provided by an embodiment of the present invention includes a reagent blending mechanism 10, a reagent kit 500 and a containing bottle 600, the containing bottle 600 is used for containing a suspension reagent with magnetic beads, a through hole 510 is provided on the reagent kit 500, and the containing bottle 600 is rotatably disposed in the through hole 510. Generally, in order to prevent the magnetic beads in the holding bottle 600 from depositing to the bottom of the holding bottle 600 and affecting the test result during the transportation of the suspension reagent, the suspension reagent in the holding bottle 600 must be continuously mixed by the reagent mixing mechanism 10.
In some embodiments, the reagent blending mechanism 10 includes a turntable 100, a blending assembly 200, and a drive assembly 300. The driving assembly 300 includes a rotating shaft 310 and a driving unit 320, the rotating shaft 310 is fixedly connected to the center of the turntable 100, and the driving unit 320 is configured to drive the rotating shaft 310 to rotate, so that the rotating shaft 310 rotates the turntable 100.
The turntable 100 may be a disk shape, the edge of the turntable 100 is provided with a plurality of wedges 110 and slots 120, the plurality of wedges 110 are arranged at intervals along the circumferential direction of the turntable 100, and the wedges 110 are formed by a part of the surface of the turntable 100 with a concave set depth; a card slot 120 may be disposed proximate the wedge 110. The reagent kit 500 is further provided with a buckle, when the reagent kit 500 is matched with the wedge 110, the buckle is matched with the clamping groove 120, the wedge 110 provides a good limiting effect for the reagent kit 500, so that the reagent kit 500 is orderly arranged on the turntable 100, and the reagent kit 500 is in a buckle connection relation with the turntable 100 through the matching of the buckle and the clamping groove 120, so that the reagent kit 500 is stably and reliably fixed on the turntable 100.
The blending assembly 200 includes a support unit 210 and a blending unit 220. The supporting unit 210 is rotatably disposed on the turntable 100, one end of the supporting unit 210 is used for fixing the containing bottle 600, and the other end of the supporting unit 210 is connected with the blending unit 220. In some embodiments, the supporting unit 210 includes a connecting arm 212 and a support 211, the wedge portion 110 of the turntable 100 is opened with a through hole communicating with opposite sides (i.e., upper and lower sides) of the turntable 100, the connecting arm 212 is rotatably disposed in the through hole, and the support 211 is connected to an upper end of the connecting arm 212 and protrudes from an upper side of the turntable 100 to fixedly receive the bottle 600. In fact, when the reagent cartridge 500 is positioned in the wedge 110, the seat 211 cooperates with a groove in the bottom of the receiving bottle 600 to fix the receiving bottle 600. The kneading unit 220 is coupled to the lower end of the coupling arm 212 such that the kneading unit 220 is located at the lower side of the turntable 100.
The blending unit 220 further includes a first gear 221 and a second gear 222, both the first gear 221 and the second gear 222 may be external gears, the first gear 221 is sleeved on the rotating shaft 310 and is in a stationary state, that is, the first gear 221 is a fixed gear, the first gear 221 is always stationary regardless of the movement of the turntable 100, and the diameter of the first gear 221 is smaller than that of the turntable 100. The second gear 222 is fixed to the lower end of the connecting arm 212, and the first gear 221 and the second gear 222 are in an external meshing relationship. In other embodiments, the first gear 221 is an internal gear, and the diameter of the first gear 221 may be larger than the diameter of the turntable 100, and the first gear 221 and the second gear 222 are in an internal meshing relationship.
When the turntable 100 rotates, the containing bottle 600 revolves around the rotation shaft 310 along with the reagent cartridge 500, and when the containing bottle 600 revolves, because the second gear 222 is engaged with the first gear 221, under the action of the first gear 221, the second gear 222 rotates and drives the connecting arm 212 to rotate in the through hole, and then the containing bottle 600 is driven by the support 211 to rotate in the through hole 510 of the reagent cartridge 500. Therefore, under the combined action of the rotation of the turntable 100 and the blending assembly 200, the containing bottle 600 revolves and rotates simultaneously, so that the magnetic bead suspension reagent in the containing bottle 600 forms turbulent flow to generate strong vortex, the vortex enables the magnetic bead suspension reagent to be automatically blended, and the magnetic beads are always in a suspension state without precipitation.
The driving unit 320 includes a motor 321, a pulley 323, and a transmission belt 322, the pulley 323 is installed at the lower end of the rotating shaft 310, and the transmission belt 322 is sleeved on the pulley 323 and the output shaft of the motor 321. When the motor 321 is started, the motor 321 drives the pulley 323 to rotate through the transmission belt 322, and finally the pulley 323 drives the turntable 100 to rotate through the rotating shaft 310. Of course, the driving unit 320 may be replaced by a gear mechanism or a link mechanism as long as the rotating shaft 310 can be driven to rotate.
In some embodiments, the reagent mixing mechanism 10 further includes a sleeve 400, the sleeve 400 is enclosed into a housing 410, and the turntable 100 is located in the housing 410. The sleeve 400 may further include a protective cover, which can cover the entire turntable 100 in the receiving cavity 410, and the protective cover can provide a good sealing protection for the turntable 100. The sleeve 400 can be further provided with an air exhaust element, for example, the air exhaust element can be a dehumidifying fan or the like, the dehumidifying fan is arranged on the inner wall of the sleeve 400, the dehumidifying fan can effectively remove the humid air in the accommodating cavity 410, and a good drying environment can be always kept in the accommodating cavity 410. The diameter of the turntable 100 is smaller than the inner diameter of the sleeve 400. In other embodiments, for example, the inner wall of the sleeve 400 may be provided with an annular groove, which is engaged with the edge of the rotating disc 100, so that the rotating disc 100 can rotate in the receiving cavity 410 more smoothly. For another example, one or more pulleys and sliding grooves are disposed between the turntable 100 and the sleeve 400, which can also improve the smoothness of the movement of the turntable 100.
The driving assembly 300 further includes a fixing plate 700, the fixing plate 700 is fixed at the bottom of the sleeve 400, and both the motor 321 and the pulley 323 can be mounted on the fixing plate 700. The fixing plate 700 may further include a mounting hole communicating with the receiving cavity 410, and an end of the rotation shaft 310 connected to the pulley 323 may be fixedly connected to the turntable 100 through the mounting hole and the receiving cavity 410. The rotating shaft 310 may be sleeved with a bearing 311, the bearing 311 may be connected between the fixing plate 700 and the turntable 100, and by providing the bearing 311, the frictional resistance during the rotation of the rotating shaft 310 may be reduced.
Through setting up carousel 100, blending subassembly 200 and drive assembly 300, drive assembly 300's pivot 310 is connected with carousel 100, drive carousel 100 pivoted in-process at pivot 310, holding bottle 600 revolves around pivot 310, and simultaneously, blending subassembly 200 drive holding bottle 600 rotation, thereby carry out the mixing to holding bottle 600's reagent, consequently, need not to set up other extra structures and can realize the smooth mixing of reagent, the structure of whole reagent mixing mechanism 10 has been simplified like this, the volume of reagent mixing mechanism 10 has been reduced, finally realize simple, compact and efficient requirement.
The utility model also provides a chemiluminescence immunoassay appearance 30, this chemiluminescence immunoassay appearance 30 includes arm 800, reagent needle 900 and foretell reagent storage device 20, and reagent needle 900 sets up on arm 800, and reagent needle 900 can absorb the suspension reagent that has the magnetic bead in the holding bottle 600. The chemiluminescent immunoassay analyzer 30 also meets the requirements of being simple, compact and efficient.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.
Claims (10)
1. The utility model provides a reagent mixing mechanism for carry out the mixing to the reagent in the holding bottle, its characterized in that includes:
a rotating disk, a rotating disk and a rotating disk,
the blending assembly comprises a supporting unit and a blending unit, the supporting unit is rotatably arranged on the turntable, one end of the supporting unit is used for fixing a containing bottle, and the other end of the supporting unit is connected with the blending unit; and
the driving assembly comprises a rotating shaft and a driving unit, the rotating shaft is fixedly connected with the turntable, and the driving unit is used for driving the rotating shaft to drive the turntable to rotate;
when the rotary table rotates, the supporting unit and the containing bottle revolve around the rotary table, and meanwhile, the blending unit drives the supporting unit and the containing bottle to rotate to achieve reagent blending.
2. The reagent blending mechanism of claim 1, wherein the supporting unit comprises a connecting arm and a support, the turntable is provided with a through hole communicated with two opposite sides of the turntable, the connecting arm is rotatably arranged in the through hole, the support is arranged on the connecting arm and extends out of one side of the turntable to fix the containing bottle, and the blending unit is connected with the connecting arm and is positioned on the other side of the turntable.
3. The reagent blending mechanism of claim 1, wherein the blending unit comprises a first gear and a second gear, the first gear is sleeved on the rotating shaft and is in a static state, and the second gear is fixed on the supporting unit and can be meshed with the first gear; when the turntable rotates, the second gear rotates relative to the first gear to drive the supporting unit to rotate.
4. The reagent mixing mechanism of claim 3, wherein the diameter of the first gear is smaller than the diameter of the turntable, and the first gear and the second gear are externally engaged.
5. The reagent mixing mechanism according to claim 1, wherein the driving unit comprises a motor, a belt wheel and a conveying belt, the belt wheel is installed on the rotating shaft, and the conveying belt is sleeved on the belt wheel and an output shaft of the motor.
6. The reagent mixing mechanism of claim 1, further comprising a sleeve, wherein the sleeve encloses a containing cavity, and the turntable is located in the containing cavity.
7. The reagent mixing mechanism of claim 6, wherein the driving assembly further comprises a fixing plate, the sleeve is mounted on the fixing plate, and the driving unit is connected with the fixing plate.
8. The reagent mixing mechanism of claim 1, further comprising any one of:
the rotary disc is provided with a plurality of wedge positions for matching with the reagent kit, and the wedge positions are arranged at intervals along the circumferential direction of the rotary disc;
a clamping groove is formed in the rotary disc and used for being matched with a buckle on the kit;
the rotating shaft is sleeved with a bearing, and the bearing is connected with the rotating disc.
9. A reagent storage device, which is characterized by comprising a reagent box, a containing bottle and the reagent blending mechanism of any one of claims 1 to 8, wherein the containing bottle is rotatably arranged in the reagent box and is connected with the supporting unit.
10. A chemiluminescent immunoassay analyzer comprising a mechanical arm, a reagent needle disposed on the mechanical arm and capable of aspirating a reagent in a containment vial, and the reagent storage device of claim 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920600625.XU CN210079376U (en) | 2019-04-29 | 2019-04-29 | Reagent mixing mechanism, reagent storage device and chemiluminescence immunoassay appearance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920600625.XU CN210079376U (en) | 2019-04-29 | 2019-04-29 | Reagent mixing mechanism, reagent storage device and chemiluminescence immunoassay appearance |
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| Publication Number | Publication Date |
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| CN210079376U true CN210079376U (en) | 2020-02-18 |
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| CN201920600625.XU Active CN210079376U (en) | 2019-04-29 | 2019-04-29 | Reagent mixing mechanism, reagent storage device and chemiluminescence immunoassay appearance |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114931879A (en) * | 2022-06-23 | 2022-08-23 | 珠海丽珠试剂股份有限公司 | Reagent blending device and reagent storage equipment and automatic analysis system applying same |
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2019
- 2019-04-29 CN CN201920600625.XU patent/CN210079376U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114931879A (en) * | 2022-06-23 | 2022-08-23 | 珠海丽珠试剂股份有限公司 | Reagent blending device and reagent storage equipment and automatic analysis system applying same |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP02 | Change in the address of a patent holder |
Address after: 518000 412, plant 2, No. 6352, Pingshan Avenue, Shatian community, Kengzi street, Pingshan District, Shenzhen City, Guangdong Province Patentee after: Aite Biotechnology (Shenzhen) Co.,Ltd. Address before: 518051 615-2, floor 6, middle section, building 25, West Science Park, Yuehai street, Nanshan District, Shenzhen, Guangdong Patentee before: Aite Biotechnology (Shenzhen) Co.,Ltd. |
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| CP02 | Change in the address of a patent holder |