CN109498491A - A kind of hydrogel Chinese herb medicine eye paste and its preparation process - Google Patents

A kind of hydrogel Chinese herb medicine eye paste and its preparation process Download PDF

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CN109498491A
CN109498491A CN201811607049.8A CN201811607049A CN109498491A CN 109498491 A CN109498491 A CN 109498491A CN 201811607049 A CN201811607049 A CN 201811607049A CN 109498491 A CN109498491 A CN 109498491A
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extract
root extract
water
hydrogel
chinese herb
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宁鑫
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Guangzhou Sike International Biotech Co Ltd
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Guangzhou Sike International Biotech Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin

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Abstract

The invention discloses a kind of hydrogel Chinese herb medicine eye paste and its preparation processes, formula includes: glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, Bacillus acidi lactici, butanediol, 1,2- pentanediol, kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed extract, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract, methyl hydroxybenzoate, Sensiva SC50, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin, peppermint alcohol and water;Preparation process, including step 1, raw material are chosen;Step 2, water-bath reflux;Step 3 collects cooling;Drug is added in step 4;Step 5, deaeration molding;Step 6 collects weighing;The invention solves the disadvantage that common water borne eye sticker, and lipid Chinese medicine herbal ingredients can be added and achieve the purpose that aqueous traditional Chinese medicine ingredients are added by modified, make more functional component volumes and be deep into eye skin, improve eye problems.

Description

A kind of hydrogel Chinese herb medicine eye paste and its preparation process
Technical field
The present invention relates to eye sticker technical field, specially a kind of hydrogel Chinese herb medicine eye paste and its preparation process.
Background technique
Now, product in the market is essentially all aqueous eye sticker, and many eye sticker products are in use because of functional component It absorbs by thick thinning, is vapor evaporation in fact, and many nutritional ingredients are all lipids, do not dissolve in aqueous eye sticker In, therefore, the drawbacks of content of effective component is very little in aqueous eye sticker, these are all aqueous eye stickers.
Summary of the invention
The purpose of the present invention is to provide a kind of hydrogel Chinese herb medicine eye paste and its preparation processes, to solve above-mentioned background technique The problem of middle proposition.
In order to solve the above technical problem, the present invention provides following technical solutions: a kind of hydrogel Chinese herb medicine eye paste, formula packet Include: glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, Bacillus acidi lactici, butanediol, 1,2- pentanediol, kuh-seng root extract, Swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed extract, fructus lycii root extract, honeysuckle extract, Radix Polygalae mention Take object, dandelion extract, methyl hydroxybenzoate, Sensiva SC50, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, chlorobenzene sweet Ether, peppermint alcohol and water;The mass fraction of each component are as follows: the glycerol of 10-20%, the Sodium Polyacrylate of 1-6%, 1-7% orange peel Glycosides methyl chalcone, the Bacillus acidi lactici of 2-5%, the butanediol of 1-6%, 1, the 2- pentanediol of 1-7%, 2-8% radix sophorae mention Take blunt leaf Cassia seed extract, the 2- of object, the swollen fruit Radix root extract of 2-8%, the radix scutellariae root extract of 2-8%, 2-8% 8% fructus lycii root extract, the honeysuckle extract of 2-8%, the milkwort extract of 2-8%, 2-8% dandelion extract, 2- 8% methyl hydroxybenzoate, the Sensiva SC50 of 2-8%, the Sodium Hyaluronate of 5-10%, the Phenoxyethanol of 1-8%, 1-8% 1,2- hexylene glycol, the Chlorphenesin of 1-5%, the menthol of 1-8% and 8-20% water.
A kind of preparation process of hydrogel Chinese herb medicine eye paste, including step 1, raw material are chosen;Step 2, water-bath reflux;Step Three, collect cooling;Drug is added in step 4;Step 5, deaeration molding;Step 6 collects weighing;
Wherein in the above step 1, it is respectively according to the mass percentage of each component: glycerol, the 1-6% of 10-20% Sodium Polyacrylate, the aurantiamarin methyl chalcone of 1-7%, the Bacillus acidi lactici of 2-5%, the butanediol of 1-6%, 1-7% 1, 2- pentanediol, the kuh-seng root extract of 2-8%, the swollen fruit Radix root extract of 2-8%, 2-8% radix scutellariae root extract, 2- The Radix Polygalae extraction of 8% blunt leaf Cassia seed extract, the fructus lycii root extract of 2-8%, the honeysuckle extract of 2-8%, 2-8% Object, the dandelion extract of 2-8%, the methyl hydroxybenzoate of 2-8%, the Sensiva SC50 of 2-8%, 5-10% hyaluronic acid Sodium, the Phenoxyethanol of 1-8%, 1, the 2- hexylene glycol of 1-8%, the Chlorphenesin of 1-5%, the menthol of 1-8% and 8-20% Water is chosen, and is weighed according to the sum of weight percent for 1;
Wherein in above-mentioned steps two, by glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, Bacillus acidi lactici, fourth two Alcohol, 1,2- pentanediol, methyl hydroxybenzoate, Sensiva SC50, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin and Menthol is added in water-bath, its water-bath is made to flow back to form homogeneous solution;
Wherein in above-mentioned steps three, after acquired solution stirring completely in above-mentioned steps two, collection is cooled to room temperature;
Wherein in above-mentioned steps four, by kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed extract, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract and water are added to above-mentioned step In rapid three in acquired solution, it is made sufficiently to dissolve and be slowly stirred;
Wherein in above-mentioned steps five, deaeration molding the following steps are included:
1) by above-mentioned mixed solution, under the conditions of vacuum degree is not less than -0.06MPa, stirring avoids gas up to being uniformly mixed The generation of bubble;
2) above-mentioned mixed solution is poured into molding die, is cooled into hydrogel semi-finished product;
Wherein in above-mentioned steps six, after hydrogel semi-finished product obtained in step 5 are collected and are weighed, selection Qualified finished product.
According to the above technical scheme, the Bacillus acidi lactici also can be replaced soya-bean milk tunning filtrate.
According to the above technical scheme, in the step 2, bath temperature is 70-85 DEG C, water bath time 1-1.5h.
According to the above technical scheme, in the step 3, mixing speed 50-60rpm, mixing time 5-10min.
According to the above technical scheme, in the step 4, mixing speed 40-55rpm, mixing time 10-15min.
According to the above technical scheme, the step 5 1) in, mixing speed 65-80rpm, mixing time 5-30min.
Compared with prior art, the beneficial effects obtained by the present invention are as follows being: the hydrogel Chinese herb medicine eye paste and its preparation process, It is a kind of novel bionical material of cutaneous penetration high-molecular biologic of certain moduli personification body skin texture using import medical material Material, has the lipophilicity network structure closely similar with eye part skin, and the lipid eye patch of formation can adhere to cutin table by stream rapidly In place of the convex-concave in face, the area contacted with eye part skin is expanded significantly, increases the adherency to eye part skin and transdermal effect;In The transdermal characteristic of the slow controlled release of medicine and preferable water lock;The effect of common eye sticker decades of times, overturned the water of traditional eye sticker with Cloth has good applicating property and absorption function, moisture and nutrient needed for supplementing eye skin, and eye circumference skin of moistening improves eye Portion's skin problem takees good care of eye skin, keeps skin flexible, smooth careful.
Detailed description of the invention
Attached drawing is used to provide further understanding of the present invention, and constitutes part of specification, with reality of the invention It applies example to be used to explain the present invention together, not be construed as limiting the invention.In the accompanying drawings:
Fig. 1 is that technique of the invention founds flow chart.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, the present invention provides a kind of technical solution:
Embodiment 1:
A kind of hydrogel Chinese herb medicine eye paste, formula include: glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, lactic acid bar Bacterium, butanediol, 1,2- pentanediol, kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed mention Take object, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract, methyl hydroxybenzoate, Sensiva SC50, thoroughly Bright matter acid sodium, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin, peppermint alcohol and water;The mass fraction of each component are as follows: 10% it is sweet Oil, 3% Sodium Polyacrylate, 3% aurantiamarin methyl chalcone, 2% Bacillus acidi lactici, 3% butanediol, 3% 1,2- Pentanediol, 4% kuh-seng root extract, 4% swollen fruit Radix root extract, 4% radix scutellariae root extract, 4% blunt leaf are determined Bright seed extract, 4% fructus lycii root extract, 4% honeysuckle extract, 4% milkwort extract, 4% dandelion extract Object, 4% methyl hydroxybenzoate, 4% Sensiva SC50,5% Sodium Hyaluronate, 3% Phenoxyethanol, 3% 1,2- oneself Glycol, 3% Chlorphenesin, 3% menthol and 19% water.
A kind of preparation process of hydrogel Chinese herb medicine eye paste, including step 1, raw material are chosen;Step 2, water-bath reflux;Step Three, collect cooling;Drug is added in step 4;Step 5, deaeration molding;Step 6 collects weighing;
Wherein in the above step 1, be respectively according to the mass percentage of each component: 10% glycerol, 3% it is poly- Sodium acrylate, 3% aurantiamarin methyl chalcone, 2% Bacillus acidi lactici, 3% butanediol, 3% 1,2- pentanediol, 4% Kuh-seng root extract, 4% swollen fruit Radix root extract, 4% radix scutellariae root extract, 4% blunt leaf Cassia seed extract, 4% fructus lycii root extract, 4% honeysuckle extract, 4% milkwort extract, 4% dandelion extract, 4% oxybenzene Methyl esters, 4% Sensiva SC50,5% Sodium Hyaluronate, 3% Phenoxyethanol, 3% 1,2- hexylene glycol, 3% chlorine The sweet ether of benzene, 3% menthol and 19% water are chosen, and are weighed according to the sum of weight percent for 1;
Wherein in above-mentioned steps two, by glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, Bacillus acidi lactici, fourth two Alcohol, 1,2- pentanediol, methyl hydroxybenzoate, Sensiva SC50, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin and Menthol is added in water-bath, its water-bath is made to flow back to form homogeneous solution, and bath temperature is 70-85 DEG C, water bath time 1- 1.5h;
Wherein in above-mentioned steps three, after acquired solution stirring completely in above-mentioned steps two, collection is cooled to room temperature, and is stirred Mixing speed is 50-60rpm, mixing time 5-10min;
Wherein in above-mentioned steps four, by kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed extract, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract and water are added to above-mentioned step In rapid three in acquired solution, it is made sufficiently to dissolve and be slowly stirred, mixing speed 40-55rpm, mixing time 10- 15min;
Wherein in above-mentioned steps five, deaeration molding the following steps are included:
1) by above-mentioned mixed solution, under the conditions of vacuum degree is not less than -0.06MPa, stirring avoids gas up to being uniformly mixed The generation of bubble, mixing speed 65-80rpm, mixing time 5-30min;
2) above-mentioned mixed solution is poured into molding die, is cooled into hydrogel semi-finished product;
Wherein in above-mentioned steps six, after hydrogel semi-finished product obtained in step 5 are collected and are weighed, selection Qualified finished product.
Wherein, Bacillus acidi lactici also can be replaced soya-bean milk tunning filtrate.
Embodiment 2:
A kind of hydrogel Chinese herb medicine eye paste, formula include: glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, lactic acid bar Bacterium, butanediol, 1,2- pentanediol, kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed mention Take object, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract, methyl hydroxybenzoate, Sensiva SC50, thoroughly Bright matter acid sodium, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin, peppermint alcohol and water;The mass fraction of each component are as follows: 15% it is sweet Oil, 3% Sodium Polyacrylate, 3% aurantiamarin methyl chalcone, 2% Bacillus acidi lactici, 3% butanediol, 3% 1,2- Pentanediol, 4% kuh-seng root extract, 4% swollen fruit Radix root extract, 4% radix scutellariae root extract, 4% blunt leaf are determined Bright seed extract, 4% fructus lycii root extract, 4% honeysuckle extract, 4% milkwort extract, 4% dandelion extract Object, 4% methyl hydroxybenzoate, 4% Sensiva SC50,5% Sodium Hyaluronate, 3% Phenoxyethanol, 3% 1,2- oneself Glycol, 3% Chlorphenesin, 3% menthol and 14% water.
A kind of preparation process of hydrogel Chinese herb medicine eye paste, including step 1, raw material are chosen;Step 2, water-bath reflux;Step Three, collect cooling;Drug is added in step 4;Step 5, deaeration molding;Step 6 collects weighing;
Wherein in the above step 1, be respectively according to the mass percentage of each component: 15% glycerol, 3% it is poly- Sodium acrylate, 3% aurantiamarin methyl chalcone, 2% Bacillus acidi lactici, 3% butanediol, 3% 1,2- pentanediol, 4% Kuh-seng root extract, 4% swollen fruit Radix root extract, 4% radix scutellariae root extract, 4% blunt leaf Cassia seed extract, 4% fructus lycii root extract, 4% honeysuckle extract, 4% milkwort extract, 4% dandelion extract, 4% oxybenzene Methyl esters, 4% Sensiva SC50,5% Sodium Hyaluronate, 3% Phenoxyethanol, 3% 1,2- hexylene glycol, 3% chlorine The sweet ether of benzene, 3% menthol and 14% water are chosen, and are weighed according to the sum of weight percent for 1;
Wherein in above-mentioned steps two, by glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, Bacillus acidi lactici, fourth two Alcohol, 1,2- pentanediol, methyl hydroxybenzoate, Sensiva SC50, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin and Menthol is added in water-bath, its water-bath is made to flow back to form homogeneous solution, and bath temperature is 70-85 DEG C, water bath time 1- 1.5h;
Wherein in above-mentioned steps three, after acquired solution stirring completely in above-mentioned steps two, collection is cooled to room temperature, and is stirred Mixing speed is 50-60rpm, mixing time 5-10min;
Wherein in above-mentioned steps four, by kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed extract, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract and water are added to above-mentioned step In rapid three in acquired solution, it is made sufficiently to dissolve and be slowly stirred, mixing speed 40-55rpm, mixing time 10- 15min;
Wherein in above-mentioned steps five, deaeration molding the following steps are included:
1) by above-mentioned mixed solution, under the conditions of vacuum degree is not less than -0.06MPa, stirring avoids gas up to being uniformly mixed The generation of bubble, mixing speed 65-80rpm, mixing time 5-30min;
2) above-mentioned mixed solution is poured into molding die, is cooled into hydrogel semi-finished product;
Wherein in above-mentioned steps six, after hydrogel semi-finished product obtained in step 5 are collected and are weighed, selection Qualified finished product.
Wherein, Bacillus acidi lactici also can be replaced soya-bean milk tunning filtrate.
Embodiment 3:
A kind of hydrogel Chinese herb medicine eye paste, formula include: glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, lactic acid bar Bacterium, butanediol, 1,2- pentanediol, kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed mention Take object, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract, methyl hydroxybenzoate, Sensiva SC50, thoroughly Bright matter acid sodium, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin, peppermint alcohol and water;The mass fraction of each component are as follows: 20% it is sweet Oil, 3% Sodium Polyacrylate, 3% aurantiamarin methyl chalcone, 2% Bacillus acidi lactici, 3% butanediol, 3% 1,2- Pentanediol, 4% kuh-seng root extract, 4% swollen fruit Radix root extract, 4% radix scutellariae root extract, 4% blunt leaf are determined Bright seed extract, 4% fructus lycii root extract, 4% honeysuckle extract, 4% milkwort extract, 4% dandelion extract Object, 4% methyl hydroxybenzoate, 4% Sensiva SC50,5% Sodium Hyaluronate, 3% Phenoxyethanol, 3% 1,2- oneself Glycol, 3% Chlorphenesin, 3% menthol and 8% water.
A kind of preparation process of hydrogel Chinese herb medicine eye paste, including step 1, raw material are chosen;Step 2, water-bath reflux;Step Three, collect cooling;Drug is added in step 4;Step 5, deaeration molding;Step 6 collects weighing;
Wherein in the above step 1, be respectively according to the mass percentage of each component: 20% glycerol, 3% it is poly- Sodium acrylate, 3% aurantiamarin methyl chalcone, 2% Bacillus acidi lactici, 3% butanediol, 3% 1,2- pentanediol, 4% Kuh-seng root extract, 4% swollen fruit Radix root extract, 4% radix scutellariae root extract, 4% blunt leaf Cassia seed extract, 4% fructus lycii root extract, 4% honeysuckle extract, 4% milkwort extract, 4% dandelion extract, 4% oxybenzene Methyl esters, 4% Sensiva SC50,5% Sodium Hyaluronate, 3% Phenoxyethanol, 3% 1,2- hexylene glycol, 3% chlorine The sweet ether of benzene, 3% menthol and 8% water are chosen, and are weighed according to the sum of weight percent for 1;
Wherein in above-mentioned steps two, by glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, Bacillus acidi lactici, fourth two Alcohol, 1,2- pentanediol, methyl hydroxybenzoate, Sensiva SC50, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin and Menthol is added in water-bath, its water-bath is made to flow back to form homogeneous solution, and bath temperature is 70-85 DEG C, water bath time 1- 1.5h;
Wherein in above-mentioned steps three, after acquired solution stirring completely in above-mentioned steps two, collection is cooled to room temperature, and is stirred Mixing speed is 50-60rpm, mixing time 5-10min;
Wherein in above-mentioned steps four, by kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed extract, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract and water are added to above-mentioned step In rapid three in acquired solution, it is made sufficiently to dissolve and be slowly stirred, mixing speed 40-55rpm, mixing time 10- 15min;
Wherein in above-mentioned steps five, deaeration molding the following steps are included:
1) by above-mentioned mixed solution, under the conditions of vacuum degree is not less than -0.06MPa, stirring avoids gas up to being uniformly mixed The generation of bubble, mixing speed 65-80rpm, mixing time 5-30min;
2) above-mentioned mixed solution is poured into molding die, is cooled into hydrogel semi-finished product;
Wherein in above-mentioned steps six, after hydrogel semi-finished product obtained in step 5 are collected and are weighed, selection Qualified finished product.
Wherein, Bacillus acidi lactici also can be replaced soya-bean milk tunning filtrate.
The end product properties of above-described embodiment are as follows:
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment Intrinsic element.
Finally, it should be noted that the foregoing is only a preferred embodiment of the present invention, it is not intended to restrict the invention, Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features. All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention Within protection scope.

Claims (7)

1. a kind of hydrogel Chinese herb medicine eye paste, it is characterised in that: formula includes: glycerol, Sodium Polyacrylate, aurantiamarin methyl Cha Er Ketone, Bacillus acidi lactici, butanediol, 1,2- pentanediol, kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia seed extract, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract, methyl hydroxybenzoate, ethyl hexyl Base glycerol, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin, peppermint alcohol and water;The mass fraction of each component are as follows: The glycerol of 10-20%, the Sodium Polyacrylate of 1-6%, 1-7% aurantiamarin methyl chalcone, the Bacillus acidi lactici of 2-5%, 1-6% Butanediol, 1, the 2- pentanediol of 1-7%, the kuh-seng root extract of 2-8%, 2-8% swollen fruit Radix root extract, 2-8% Radix scutellariae root extract, the blunt leaf Cassia seed extract of 2-8%, the fructus lycii root extract of 2-8%, 2-8% honeysuckle extract, The milkwort extract of 2-8%, the dandelion extract of 2-8%, the methyl hydroxybenzoate of 2-8%, the Sensiva SC50 of 2-8%, 5- 10% Sodium Hyaluronate, the Phenoxyethanol of 1-8%, 1, the 2- hexylene glycol of 1-8%, the Chlorphenesin of 1-5%, 1-8% it is thin The water of the pure and mild 8-20% of lotus.
2. a kind of preparation process of hydrogel Chinese herb medicine eye paste, including step 1, raw material is chosen;Step 2, water-bath reflux;Step Three, collect cooling;Drug is added in step 4;Step 5, deaeration molding;Step 6 collects weighing;It is characterized by:
Wherein in the above step 1, be respectively according to the mass percentage of each component: the glycerol of 10-20%, 1-6% it is poly- Sodium acrylate, the aurantiamarin methyl chalcone of 1-7%, the Bacillus acidi lactici of 2-5%, the butanediol of 1-6%, 1-7% 1,2- penta Glycol, the kuh-seng root extract of 2-8%, the swollen fruit Radix root extract of 2-8%, the radix scutellariae root extract of 2-8%, 2-8% Blunt leaf Cassia seed extract, the fructus lycii root extract of 2-8%, the honeysuckle extract of 2-8%, the milkwort extract of 2-8%, 2- 8% dandelion extract, the methyl hydroxybenzoate of 2-8%, the Sensiva SC50 of 2-8%, 5-10% Sodium Hyaluronate, 1- The water progress of 8% Phenoxyethanol, 1, the 2- hexylene glycol of 1-8%, the Chlorphenesin of 1-5%, the menthol of 1-8% and 8-20% It chooses, and is weighed according to the sum of weight percent for 1;
Wherein in above-mentioned steps two, by glycerol, Sodium Polyacrylate, aurantiamarin methyl chalcone, Bacillus acidi lactici, butanediol, 1, 2- pentanediol, methyl hydroxybenzoate, Sensiva SC50, Sodium Hyaluronate, Phenoxyethanol, 1,2- hexylene glycol, Chlorphenesin and peppermint Alcohol is added in water-bath, its water-bath is made to flow back to form homogeneous solution;
Wherein in above-mentioned steps three, after acquired solution stirring completely in above-mentioned steps two, collection is cooled to room temperature;
Wherein in above-mentioned steps four, by kuh-seng root extract, swollen fruit Radix root extract, radix scutellariae root extract, blunt leaf Cassia Seed extract, fructus lycii root extract, honeysuckle extract, milkwort extract, dandelion extract and water are added to above-mentioned step 3 In middle acquired solution, it is made sufficiently to dissolve and be slowly stirred;
Wherein in above-mentioned steps five, deaeration molding the following steps are included:
1) by above-mentioned mixed solution, under the conditions of vacuum degree is not less than -0.06MPa, stirring avoids bubble up to being uniformly mixed It generates;
2) above-mentioned mixed solution is poured into molding die, is cooled into hydrogel semi-finished product;
Wherein in above-mentioned steps six, after hydrogel semi-finished product obtained in step 5 are collected and are weighed, selection is qualified Finished product.
3. a kind of hydrogel Chinese herb medicine eye paste according to claim 1, it is characterised in that: the Bacillus acidi lactici also can be replaced Soya-bean milk tunning filtrate.
4. a kind of preparation process of hydrogel Chinese herb medicine eye paste according to claim 2, it is characterised in that: the step 2 In, bath temperature is 70-85 DEG C, water bath time 1-1.5h.
5. a kind of preparation process of hydrogel Chinese herb medicine eye paste according to claim 2, it is characterised in that: the step 3 In, mixing speed 50-60rpm, mixing time 5-10min.
6. a kind of preparation process of hydrogel Chinese herb medicine eye paste according to claim 2, it is characterised in that: the step 4 In, mixing speed 40-55rpm, mixing time 10-15min.
7. a kind of preparation process of hydrogel Chinese herb medicine eye paste according to claim 2, it is characterised in that: the step 5 1) In, mixing speed 65-80rpm, mixing time 5-30min.
CN201811607049.8A 2018-12-27 2018-12-27 A kind of hydrogel Chinese herb medicine eye paste and its preparation process Pending CN109498491A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643722A (en) * 2020-06-29 2020-09-11 华仁药业股份有限公司 Sodium hyaluronate application containing icodextrin
CN113230236A (en) * 2021-04-29 2021-08-10 山东优杰生物科技有限公司 Plaster for removing onychomycosis and preparation method thereof
CN115363964A (en) * 2021-05-18 2022-11-22 华南理工大学 Borneol-based temperature-sensitive hydrogel eye mask for relieving eye problems and preparation method thereof
CN115487103A (en) * 2021-11-02 2022-12-20 上海丽舒丹医药科技有限公司 Plant-derived sunscreen synergist composition and application thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643722A (en) * 2020-06-29 2020-09-11 华仁药业股份有限公司 Sodium hyaluronate application containing icodextrin
CN113230236A (en) * 2021-04-29 2021-08-10 山东优杰生物科技有限公司 Plaster for removing onychomycosis and preparation method thereof
CN115363964A (en) * 2021-05-18 2022-11-22 华南理工大学 Borneol-based temperature-sensitive hydrogel eye mask for relieving eye problems and preparation method thereof
CN115487103A (en) * 2021-11-02 2022-12-20 上海丽舒丹医药科技有限公司 Plant-derived sunscreen synergist composition and application thereof
CN115487103B (en) * 2021-11-02 2024-02-23 上海丽舒丹医药科技有限公司 Plant-derived sun-screening synergistic agent composition and application thereof

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Application publication date: 20190322