CN1094629A - Children's's QI invigorating detoxifcation electuary and preparation method - Google Patents
Children's's QI invigorating detoxifcation electuary and preparation method Download PDFInfo
- Publication number
- CN1094629A CN1094629A CN 93105425 CN93105425A CN1094629A CN 1094629 A CN1094629 A CN 1094629A CN 93105425 CN93105425 CN 93105425 CN 93105425 A CN93105425 A CN 93105425A CN 1094629 A CN1094629 A CN 1094629A
- Authority
- CN
- China
- Prior art keywords
- radix
- semen
- children
- herba
- electuary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to medicinal preparation and preparation method thereof.Chinese medicine of the present invention is grouped into by following one-tenth: the Radix Astragali 400-600g, Herba Ephedrae 205-305g, Rhizoma Dioscoreae 205-305g, Radix Seselis mairei 400-600g, Radix Platycodonis 200-350g, Semen Armeniacae Amarum 200-350g, Semen Sinapis Albae 200-350g, Semen Lepidii (Semen Descurainiae) 200-350g, Fructus Crataegi 400-600g, Radix Scutellariae 400-600g, Herba Kalimeridis 400-500g, Radix Glycyrrhizae 200-350g.Cure mainly diseases such as children's's anemofrigid cold, cough in the above-mentioned Chinese medicine, total effective rate reaches 93.7%.
Description
The present invention relates to the medicinal preparation of the material preparation that derives from plant and the preparation method of this medicinal preparation.
Chinese patent application CN1060122A(application number 91105015.9) discloses a kind of " prescription of child, old people's bronchitis medicine and manufacture method ", it is characterized in that the prescription of this Chinese medicine and each pharmaceutical quantities ratio are: Herba Ephedrae 14-20%, Semen Armeniacae Amarum 25-30%, Radix Glycyrrhizae 5-10%, Radix Platycodonis 14-20%, Semen Ginkgo (shelling) 14-20%, Gypsum Fibrosum 28-35%.Its method for making for earlier with Herba Ephedrae, Semen Armeniacae Amarum, Radix Glycyrrhizae, Radix Platycodonis, that Semen Ginkgo (shelling) is pressed the formula proportion infusion is qualified, grind into the medicine end through drying, through 100 mesh sieves, as above certain proportion be crushed into powder, through the Gypsum Fibrosum of 100 mesh sieves, uniform mixing, get account for the Mel of the 60-100% of said medicine amount of the mixture or white sugar be placed on refine in iron pan or the steel pot for goldenrod liquid for spending, get this goldenrod liquid uniform mixing medicinal mixture, stir, make various pills or tablet, with slow fire oven dry (30-60 ℃), package encapsulation.
The objective of the invention is body constitution and characteristics at children's, provide a kind of medicinal preparation that is exclusively used in common disease in children with and preparation method thereof.
Children's's QI invigorating detoxifcation electuary of the present invention is tender and lovely at children's's internal organs, and shape gas does not fill, the equal immaturity of each organ physiological function of body, space between skin and muscles is dredged thin, weakened defensive QI, resistance against diseases is poor, the immunologic function deficiency, cold in addition temperature can not self-regulated, the breast food can not be from joint, and easy ill characteristics are according to theory of Chinese medical science, on the middle older generation's of medical circles proved recipe basis, be developed into through clinical verification.
Children's's QI invigorating detoxifcation electuary of the present invention is made up of following composition: Radix Astragali 400-600g, Herba Ephedrae 205-305g, Rhizoma Dioscoreae 205-305g, Radix Seselis mairei 400-600g, Radix Platycodonis 200-350g, Semen Armeniacae Amarum 200-350, Semen Sinapis Albae 200-350g, Semen Lepidii (Semen Descurainiae) 200-350g, Fructus Crataegi 400-600g, Radix Scutellariae 400-600g, Herba Kalimeridis 400-500g, Radix Glycyrrhizae 200-350g.
The Radix Astragali is leguminous plant Radix Astragali Astraqalus membranaceus(Fisch) Bge. Radix Astagali Astragalus membranaceus Bge, Var, mongholicus(Bge), the dry root of Hsiao records in one one of Chinese Pharmacopoeia version in 1985.
Radix Seselis mairei is the dry root of samphire Radix Seselis mairei seseli ma irei woiff. and Folium Pini Radix Saposhnikoviae Seseli Yunnanese Franch., records in Yunnan Province's provincial standard version in 1974.
Herba Ephedrae is Ephedraceae plant crawl an ephedra likiangensis Florin Ephedra Likiangensis Florin f, mairei(Florin) the dry herb stem of C.Y.Cheng or ephedra likiangensis Florin Ephedra Likiangensis Florin.Record in Yunnan Province's provincial standard version in 1974.
Radix Platycodonis is campanulaceae Platycodon grandiflouorum Platycodon qrandiflorum(Jacq) dry root of A.dc..Record in one one of Chinese Pharmacopoeia version in 1985.
Radix Scutellariae is the dry root of labiate southwest Radix Scutellariae Scutellaria amoena C, H, Wright.Record in Yunnan Province's provincial standard version in 1974.
Semen Sinapis Albae is crucifer Caulis et Folium Sinapis albee sinapis apba or mustard Brassica juncea(1) Czern, the dry mature seed of et cosa.Record in one one of Chinese Pharmacopoeia version in 1985.
Fructus Crataegi is the dry mature fruit of rosaceous plant Fructus Pyri Pashiae Crataegus pinnatifida Bge Var major.N.E.Br. Fructus Crataegi Crataegus pinnatifida Bge or Crataegi cuneatae Crategus cuneat a Sieset Zucc.Record in 1985 editions one one of Chinese Pharmacopoeia.
Semen Armeniacae Amarum: be rosaceous plant Prunus armeniaca L.var.ansu Maxim. Prunus armeniace L Var ansu Maxim Siberia Fructus Pruni Prunus Sibirica L prunus mandshuricaKoehne Prunus mandshurica(Maxim) dry mature seed of Konehne or Fructus Pruni Prunus armeniaca bitter in the mouth.Record in one one of Chinese Pharmacopoeia version in 1985.
Semen Lepidii (Semen Descurainiae) is crucifer Lepidium sativum L. Lepidium apetalum willd or descurainia sophia (l.) webb ex prantl Descurainia Sophia(L) dry mature seed of Well ex Prantl.Record in one one of Chinese Pharmacopoeia version in 1985.
Herba Kalimeridis is acanthaceous plant Herba Kalimeridis Strobilanths Cusia(Ness) the dry root and rhizome of O.Kuntze.Record in version Yunnan Province provincial standard in 1974.
Rhizoma Dioscoreae is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae Dioscorea oPPosita Thunr, records in one one of Chinese Pharmacopoeia version in 1985.
Radix Glycyrrhizae is the dry rhizome of glycyrrhizic legume Glycyrrhiza Uralensis Fisch Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat or Glycyrrhiza glabra L. Glycyrrhiza gla ra L.Record in one one of Chinese Pharmacopoeia version in 1985.
Radix Astragali benefiting QI for strengthening the superficies in this prescription, the hot warm diffusing lung, relieving exterior syndrome of Herba Ephedrae, playing supplementing QI for expelling the pathogenic factors from the body surface altogether is monarch drug.Rhizoma Dioscoreae helps Radix Astragali QI invigorating, and it is ministerial drug altogether that Radix Saposhnikoviae helps Herba Ephedrae to induce sweat.Children's's lungs are tender and lovely, and the spleen tending to insufficiency usually is pure-yang constituent, behind the exopathogen that is affected by the cold, the disease of coughing is often maximum and heavy, and exopathogen invading the interior is easily from transconversion into heat, and inhibited pulmonary QI easily causes loss of appetite, so with Radix Platycodonis, Semen Armeniacae Amarum, Semen Sinapis Albae, Semen Lepidii (Semen Descurainiae) dispersing lung-QI and dissipating phlegm, relieving cough and asthma, hawthorn digesting is good for the stomach; The dry adjuvant drug that is is altogether crossed in Radix Scutellariae, the detoxifcation of Herba Kalimeridis clearing up internal heat by using drugs of bitter in taste and cold in nature, all using warming therapy of using corrigent.The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription is for making.All medicines close to be executed, and plays the supplementing QI for expelling the pathogenic factors from the body surface relieving cough and resolving phlegm altogether, the merit that detoxifcation helps digestion.
The preparation method of children's's QI invigorating detoxifcation electuary of the present invention is made up of following steps:
(1), get Herba Ephedrae and pulverize, extract repeatedly with the widely different stream of ethanol, merge alcohol extract;
(2), all the other ten Herba indigoferae Pseudotinctoriae are pulverized, decoct with water repeatedly, decoction liquor is filtered, merging filtrate, being concentrated into relative density is 1.00-1.10(85-95 ℃), be chilled to room temperature, adding equivalent ethanol stirs, leave standstill, get supernatant and reclaim ethanol, continuing to be concentrated into relative density is 1.10-1.30(50-70 ℃) extractum;
(3), get step (two) gained extractum, in 1: 1.5-3: the ratio of 1.5-3 adds sucrose, dextrin, with step () gained Herba Ephedrae alcohol extract mixing, drying, molding, packing.
Used concentration of ethanol is 70% in preparation technology of the present invention, and the dosage form of institute's molding is pharmaceutically acceptable dosage form, as electuary, tablet, capsule etc.
Children's's QI invigorating detoxifcation electuary of the present invention is through acute toxicity test, and long term toxicity test proves, has no side effect, and have analgesic, eliminate the phlegm, suppress the effect of virus, take this electuary after 3 hours by the rabbit of " triple vaccine " pyrogenicity, cooling extent reaches 0.7-1.4 ℃; External dull and stereotyped antibacterial tests, this electuary concentration 33% and 16% o'clock, to staphylococcus aureus, Bacillus proteus is extremely responsive, to bacillus subtilis, the dysentery bacterium sensitivity; In vitro tests, this electuary on the blood-coagulation-board after dilution in 1: 2,1: 4, anti-86-1 in influenza virus A/ capital and the anti-86-37 in B/ capital are had inhibition, effect except that last two kinds of viruses suppress to have slightly the enhancing, also showed the expensive anti-86-30 of A3/ and suppresses after 2 hours in refrigerator.This electuary also has Accommodation to diarrhea due to hypofunction of the spleen, and certain immunologic function is arranged.Cure mainly children's's anemofrigid cold, diseases such as cough.Through clinical 300 example experiments, 191 examples of fully recovering account for 63.7%, produce effects 50 examples, account for 16.7%, and effective 40 examples account for 13.3%, and invalid 19 examples account for 6.3%, and total effective rate is 93.7%.
Be embodiments of the invention below:
Get Herba Ephedrae 450g and pulverize, add the widely different stream of 70% ethanol and extract secondary, it is standby to merge alcohol extract.Get Radix Astragali 470g, Rhizoma Dioscoreae 215g, Radix Seselis mairei 420g, Radix Platycodonis 210g, Semen Armeniacae Amarum 220g, Semen Sinapis Albae 230g, Semen Lepidii (Semen Descurainiae) 225g, Fructus Crataegi 500g, Radix Scutellariae 480g, Herba Kalimeridis 410g, Radix Glycyrrhizae 220g, pulverize, decoct with water secondary, each 1.5 hours, decoction liquor is filtered, merging filtrate, being concentrated into relative density is 1.08(90-95 ℃), room temperature to be chilled to adds equivalent ethanol and stirs, left standstill 12 hours, make its precipitation, get supernatant and reclaim ethanol, continuing to be concentrated into equal densities of both is 1.20(60-65 ℃) extractum, get the extractum portion, with sucrose two minutes,, make granule with above-mentioned Herba Ephedrae alcohol extract mixing, drying is made 1000g promptly, packs every bag heavy 8g.
Assay: measure the content of Herba Ephedrae epheday intermedia alkali with ephedrine hydrochloride (C with gas chromatography
10H
15NOHCl) every bag is calculated as 11.4-17.2mg.
Claims (3)
1, a kind of children's's QI invigorating detoxifcation electuary is characterized in that being made up of following composition: Radix Astragali 400-600g, Herba Ephedrae 205-305g, Rhizoma Dioscoreae 205-305g, Radix Seselis mairei 400-600g, Radix Platycodonis 200-350g, Semen Armeniacae Amarum 200-350, Semen Sinapis Albae 200-350g, Semen Lepidii (Semen Descurainiae) 200-350g, Fructus Crataegi 400-600g, Radix Scutellariae 400-600g, Herba Kalimeridis 400-500g, Radix Glycyrrhizae 200-350g.
2, according to the preparation method of the described children's's QI invigorating detoxifcation of claim 1 electuary, it is characterized in that forming by following steps:
(1), get Herba Ephedrae and pulverize, extract repeatedly with the widely different stream of ethanol, merge alcohol extract;
(2), all the other ten Herba indigoferae Pseudotinctoriae are pulverized, decoct with water repeatedly, decoction liquor is filtered, merging filtrate, being concentrated into relative density is 1.00-1.10(85-95 ℃), be chilled to room temperature, adding equivalent ethanol stirs, leave standstill, get supernatant and reclaim ethanol, continuing to be concentrated into relative density is 1.10-1.30(50-70 ℃) extractum;
(3), get step (two) gained extractum, in 1: 1.5-3: the ratio of 1.5-3 adds sucrose, dextrin, with step () gained Herba Ephedrae alcohol extract mixing, drying, molding, packing.
3,, it is characterized in that used concentration of ethanol is 70% according to the described preparation method of claim 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93105425A CN1050754C (en) | 1993-05-05 | 1993-05-05 | Supplementing qi detoxicating granule or powder preparation to be taken after being infused in boiling water for children and preparing process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93105425A CN1050754C (en) | 1993-05-05 | 1993-05-05 | Supplementing qi detoxicating granule or powder preparation to be taken after being infused in boiling water for children and preparing process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1094629A true CN1094629A (en) | 1994-11-09 |
| CN1050754C CN1050754C (en) | 2000-03-29 |
Family
ID=4985717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93105425A Expired - Lifetime CN1050754C (en) | 1993-05-05 | 1993-05-05 | Supplementing qi detoxicating granule or powder preparation to be taken after being infused in boiling water for children and preparing process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1050754C (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1069053C (en) * | 1999-01-15 | 2001-08-01 | 漳州市药物研究所 | Oral medicine for treating phlegm-heat cough |
| CN1094055C (en) * | 1998-07-30 | 2002-11-13 | 王建平 | Medicine for curing common cold and cough and its preparing process |
| CN102188591A (en) * | 2011-05-09 | 2011-09-21 | 武汉健民集团随州药业有限公司 | Traditional Chinese medicine for treating colds and preparation method thereof |
| CN102284021A (en) * | 2011-07-25 | 2011-12-21 | 王疆宏 | Lung-releasing and cough-relieving grain composite for children and preparation method and quality control method thereof |
| CN102302647A (en) * | 2011-09-05 | 2012-01-04 | 王疆宏 | Chinese medicinal composition for freeing lung and relieving exterior syndrome and clearing heat and eliminating phlegm for children and preparation method thereof |
| CN105963452A (en) * | 2016-06-24 | 2016-09-28 | 南阳医学高等专科学校第附属医院 | Traditional Chinese medicine patch for treating infantile cold cough and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1060212A (en) * | 1991-07-20 | 1992-04-15 | 肖水源 | The prescription of child, old people's bronchitis medicine and manufacture method |
-
1993
- 1993-05-05 CN CN93105425A patent/CN1050754C/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1094055C (en) * | 1998-07-30 | 2002-11-13 | 王建平 | Medicine for curing common cold and cough and its preparing process |
| CN1069053C (en) * | 1999-01-15 | 2001-08-01 | 漳州市药物研究所 | Oral medicine for treating phlegm-heat cough |
| CN102188591A (en) * | 2011-05-09 | 2011-09-21 | 武汉健民集团随州药业有限公司 | Traditional Chinese medicine for treating colds and preparation method thereof |
| CN102188591B (en) * | 2011-05-09 | 2013-02-13 | 武汉健民集团随州药业有限公司 | Traditional Chinese medicine for treating colds and preparation method thereof |
| CN102284021A (en) * | 2011-07-25 | 2011-12-21 | 王疆宏 | Lung-releasing and cough-relieving grain composite for children and preparation method and quality control method thereof |
| CN102284021B (en) * | 2011-07-25 | 2012-07-18 | 王疆宏 | Lung-releasing and cough-relieving grain composition for children and preparation method and quality control method thereof |
| CN102302647A (en) * | 2011-09-05 | 2012-01-04 | 王疆宏 | Chinese medicinal composition for freeing lung and relieving exterior syndrome and clearing heat and eliminating phlegm for children and preparation method thereof |
| CN105963452A (en) * | 2016-06-24 | 2016-09-28 | 南阳医学高等专科学校第附属医院 | Traditional Chinese medicine patch for treating infantile cold cough and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1050754C (en) | 2000-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101147788B (en) | Medicine for treating cold and upper respiratory tract infection and its lung inflammation | |
| CN101940658B (en) | Chinese medicinal composition for treating toothache and preparation method thereof | |
| WO2021169026A1 (en) | Traditional chinese medicine composition for preventing epidemics, and preparation method therefor and use thereof | |
| CN111658752A (en) | Medicine for treating diseases caused by novel coronavirus | |
| CN1222298C (en) | Medicine for treating cardiovascular disease | |
| CN104189602A (en) | Pharmaceutical composition for treating hand-foot-and-mouth disease | |
| CN1050754C (en) | Supplementing qi detoxicating granule or powder preparation to be taken after being infused in boiling water for children and preparing process thereof | |
| CN101670089A (en) | Traditional Chinese medicine for treating acute gastroenteritis | |
| CN105918946A (en) | Red date and Chinese wolfberry fruit liver tonifying composition, granules and preparation method thereof | |
| CN100569263C (en) | A kind of pharmaceutical composition for the treatment of stomachache and preparation method thereof | |
| CN111729045A (en) | A Chinese medicinal composition with qi invigorating, superficial resistance consolidating and epidemic preventing effects, and its application in preventing and treating common cold or new coronary pneumonia | |
| CN1055223C (en) | Chinese medicine preparation for treatment of gastric ulcer, duodenal ulcer and gastritis | |
| CN111097021A (en) | Traditional Chinese medicine composition for treating mild and suspected new coronary pneumonia and acute respiratory infection | |
| CN101455821A (en) | Traditional Chinese medicine composition for treating colitis | |
| CN103705578B (en) | There is blood fat reducing and Chinese medicine preparation suppressing blood glucose rising effect and preparation method thereof | |
| CN1418693A (en) | Oral liquid medicine for treating stomach-pain, and its prepn. method | |
| CN113144108A (en) | A Chinese medicinal composition for treating coronavirus and preparation method thereof | |
| CN111407808A (en) | Epidemic-resistant traditional Chinese medicine composition, preparation method and pharmaceutical application thereof | |
| CN1242800C (en) | Chinese medicine prepn for treating deficiency of spleen and stomach Yin type atrophic gastritis | |
| CN1394629A (en) | Chinese patent medicine for curing gastropathy | |
| CN112843162B (en) | Traditional Chinese medicine composition for harmonizing stomach, lowering adverse qi, clearing heat and removing dampness, preparation method and application | |
| CN106578201A (en) | Compound tea with functions of clearing lung-heat and moistening dryness | |
| CN101829312A (en) | Medicament for treating rheumatoid arthritis and preparation method thereof | |
| CN101822812A (en) | Medicament for treating pneumonia and preparation method thereof | |
| CN104399045A (en) | Medicament for treating hyperlipidemia |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C53 | Correction of patent of invention or patent application | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: WANG DENGKE TO: SUIZHOU PHARMACEUTIC PLANT |
|
| CP02 | Change in the address of a patent holder |
Address after: 441300 No. 269, Jiefang Road, Hubei, Suizhou Applicant after: Suizhou Pharmaceutic Plant Address before: 650011 No. 22, Heping Village, No. 303, Kunming Applicant before: Wang Dengke |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: WUHAN JIANMIN GROUP SUIZHOU PHARMACEUTICAL CO., LT Free format text: FORMER NAME OR ADDRESS: SUIZHOU PHARMACEUTICAL CO., LTD., WUHAN JIANMIN GROUP Owner name: SUIZHOU PHARMACEUTICAL CO., LTD., WUHAN JIANMIN GR Free format text: FORMER NAME OR ADDRESS: WUHAN JIANMIN PHARMACEUTICAL GROUP SUIZHOU PHARMACEUTICAL COMPANY Owner name: WUHAN JIANMIN PHARMACEUTICAL GROUP SUIZHOU PHARMAC Free format text: FORMER NAME OR ADDRESS: SUIZHOU PHARMACEUTIC PLANT |
|
| CP03 | Change of name, title or address |
Address after: 441300 Suizhou economic and Technological Development Zone, Hubei Patentee after: Wuhan Jianmin Group Suizhou Pharmaceutical Co.,Ltd. Address before: 441300 No. 269, Jiefang Road, Hubei, Suizhou Patentee before: Wuhan Jianmin Group Suizhou Pharmaceutical Co.,Ltd. Address after: 441300 No. 269, Jiefang Road, Hubei, Suizhou Patentee after: Wuhan Jianmin Group Suizhou Pharmaceutical Co.,Ltd. Address before: 441300 No. 269, Jiefang Road, Hubei, Suizhou Patentee before: Suizhou Pharmaceutical Company of Wuhan Jianmin Group Address after: 441300 No. 269, Jiefang Road, Hubei, Suizhou Patentee after: Suizhou Pharmaceutical Company of Wuhan Jianmin Group Address before: 441300 No. 269, Jiefang Road, Hubei, Suizhou Patentee before: Suizhou Pharmaceutic Plant |
|
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20130505 Granted publication date: 20000329 |