CN104399045A

CN104399045A - Medicament for treating hyperlipidemia

Info

Publication number: CN104399045A
Application number: CN201410729770.XA
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-03-18
Filing date: 2014-03-18
Publication date: 2015-03-11

Abstract

The invention relates to a medicament for treating hyperlipidemia. The medicament is prepared from the following raw medicaments in parts by weight: downy ground cherry fruits or herbs, date palm, changnienia amoena, Chinese pholidota herbs, rudbeckia laciniata, sanicula chinensis, schisandra propinqua, white mustard seeds, lilies, licorice, atractylodes lancea, common coltsfoot flowers, grass ferns, clematis roots, Japanese honeysuckle stems, capsicum annuum, roasted rhizoma atractylodis macrocephalae, folium artemisiae agryi, schisandra chinensis, radix paeoniae alba, American ginseng, dried gingers, papayas, angelica, centella aslatlca urban roots, cassia twigs, common club moss herbs, whorlleaf loosestrife herbs, peach seeds, Asiatic moonseed rhizome, camellia, ephedra and scorpions. The medicament for treating hyperlipidemia is reasonable in formula, and has the characteristics of definite curative effects, safety, convenience, no toxic or side effects and low cost.

Description

A kind of medicament for the treatment of hyperlipemia

The divisional application that the present invention is the applying date is on March 18th, 2014, application number is 2014100994252, denomination of invention is the invention of " a kind of medicament for the treatment of hyperlipemia ".

Technical field

The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of hyperlipemia.

Background technology

Hyperlipemia refers to that blood lipid level is too high, directly can cause the disease of some serious harm healths, as atherosclerosis, coronary heart disease, pancreatitis etc.In recent years, along with the raising day by day of people's living standard, the crowd suffering from hyperlipemia gets more and more, and even starts the trend of becoming younger.Therefore, the medicament finding treatment hyperlipemia is efficiently imperative.

Summary of the invention

The object of this invention is to provide a kind of medicament for the treatment of hyperlipemia.

In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of hyperlipemia, it is made up by weight of following bulk drugs: triangle bubble 10-20 part, Fructus Phoenicis Dactyliferae 10-20 part, Changuienia amoena Chien 10-20 part, Pseudobulbus Pholidotae Chinensis 10-20 part, Folium Rudbeckiae Laciniatae 10-20 part, sanicle 10-20 part, fragrant Caulis seu Radix Schisandrae Henryi 10-20 part, Semen Sinapis Albae 10-20 part, Bulbus Lilii 10-20 part, Radix Glycyrrhizae 10-20 part, Rhizoma Atractylodis 10-20 part, Flos Farfarae 10-20 part, Vittaria fudzinoi Mak. 10-20 part, Radix Clematidis 1-10 part, Caulis Lonicerae 1-10 part, Fructus Zanthoxyli 1-10 part, Rhizoma Atractylodis Macrocephalae (parched) 1-10 part, Folium Artemisiae Argyi 1-10 part, Fructus Schisandrae Chinensis 1-10 part, Radix Paeoniae Alba 1-10 part, Radix Panacis Quinquefolii 1-10 part, Rhizoma Zingiberis 1-5 part, Fructus Chaenomelis 1-5 part, Radix Angelicae Sinensis 1-5 part, Angiopteris magna Ching (Angiopteris majuscula Ching) 1-5 part, Ramulus Cinnamomi 1-5 part, Herba Lycopodii 1-5 part, Herba Lysimachiae Klattianae 1-5 part, Semen Persicae 1-5 part, Rhizoma Menispermi 1-5 part, Flos Camelliae Japonicae 1-5 part, Herba Ephedrae 1-5 part and Scorpio 1-5 part.

Preferably, the medicament for the treatment of hyperlipemia of the present invention is made up by weight of following bulk drugs: triangle steeps 12 parts, Fructus Phoenicis Dactyliferae 12 parts, Changuienia amoena Chien 15 parts, Pseudobulbus Pholidotae Chinensis 16 parts, Folium Rudbeckiae Laciniatae 12 parts, sanicle 10 parts, fragrant Caulis seu Radix Schisandrae Henryi 10 parts, Semen Sinapis Albae 10 parts, Bulbus Lilii 11 parts, 11 parts, Radix Glycyrrhizae, Rhizoma Atractylodis 11 parts, Flos Farfarae 10 parts, Vittaria fudzinoi Mak. 10 parts, Radix Clematidis 8 parts, Caulis Lonicerae 8 parts, Fructus Zanthoxyli 9 parts, Rhizoma Atractylodis Macrocephalae (parched) 9 parts, Folium Artemisiae Argyi 8 parts, Fructus Schisandrae Chinensis 8 parts, the Radix Paeoniae Alba 8 parts, Radix Panacis Quinquefolii 7 parts, Rhizoma Zingiberis 5 parts, Fructus Chaenomelis 2 parts, Radix Angelicae Sinensis 3 parts, Angiopteris magna Ching (Angiopteris majuscula Ching) 2 parts, Ramulus Cinnamomi 1 part, Herba Lycopodii 2 parts, Herba Lysimachiae Klattianae 1 part, 3 parts, Semen Persicae, Rhizoma Menispermi 1 part, Flos Camelliae Japonicae 2 parts, 1 part, Herba Ephedrae and Scorpio 1 part.

More preferably, described medicament can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, oral liquid or decoction.

Generally acknowledged that " organic conception ", " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs ", " compound recipe use ", " compound compatibility medication is as used military forces " are the traditional Chinese medical science the most effective most scientific several large advantages at present, wherein " compound compatibility medication is as used military forces " is the original theory of Chinese medicine of very science.The tight compatibility that in traditional Chinese medical science prescription, each medicine is all linked with one another as arrayed troops for battle is that it is better than the effective means of Western medicine formula.Tcm prescription theory is thought, each prescription, not only need to select the appropriate compatibility of suitable medicament according to etiology and pathogenesis, also should meet the basic structure of prescription simultaneously, the i.e. prescription compatibility theory of " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make " is exactly that it is based upon the scientific matching on the comprehensive judgement basis of disease pathogenesis.In medical side by too many levels, Mutiple Targets Integrate adjustment biological mechanism, can to obtain than Western medicine more lastingly, the more therapeutic effect that has no side effect of green natural, and this curative effect be based upon the above-mentioned traditional Chinese medical science tradition original theory accurate instruction on, the present invention just have followed this principle.

In compositions of the present invention:

Triangle bubble (Classification system Cardiospermum halicacabumL. [C.halicacabumL.var.microcarpum (Kumth) Bl.; C.microcaspumKunth]): nature and flavor are bitter; Pungent; Cold, there is the effect such as clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Fructus Phoenicis Dactyliferae (Classification system Phoenix dactylifera L.) nature and flavor sweet in the mouth; Warm in nature, return spleen, lung meridian, there is QI invigorating tonify deficiency, help digestion the effects such as expectorant.Changuienia amoena Chien (Classification system Changnieniaamoena Chien) nature and flavor bitter in the mouth; Cold in nature, there is the effects such as heat clearing away, removing heat from blood, removing toxic substances.Pseudobulbus Pholidotae Chinensis (Classification system var.Pectinatum) is sweet, bitter, light, cool, enters lung, liver two warp, for pulmonary tuberculosis cough, cough with asthma QI rising in reverse order etc.Folium Rudbeckiae Laciniatae (Classification system Rudbeckia laciniata L.) nature and flavor are bitter, cool, have the effects such as heat-clearing and toxic substances removing.Sanicle (Classification system Saniculachinensis) acrid in the mouth; Micro-sweet; Cool in nature, there is the effects such as removing toxic substances, hemostasis.Fragrant Caulis seu Radix Schisandrae Henryi (Classification system Schisandra rubriflora (Franch.) Rehd.etWils.) is pungent; Warm in nature, have invigorate blood circulation, the effect such as antiinflammatory.Semen Sinapis Albae: hot in nature, acrid in the mouth.Return lung meridian.Be good at warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral pain relieving.Bulbus Lilii: sweet, micro-hardship, is slightly cold, GUIXIN, lung meridian.Nourishing YIN to relieve dryness, clearing away heart-fire for tranquillization.Cure mainly deficiency of YIN chronic cough or the unsuccessful caused fidgets due to deficiency palpitation with fear of feelings will, insomnia and dreamful sleep.Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.For severe palpitation, the irregularly intermittent and regularly intermittent pulse of deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature.Return spleen, stomach warp.Have drying damp and strengthening spleen, effect of expelling wind and removing dampness.Flos Farfarae: warm in nature, acrid in the mouth.Return lung meridian.Be good at preventing phlegm from forming and stopping coughing.Have the antitussive therapeutic method to keep the adverse QI flowing downwards, lung moistening is eliminated the phlegm.Vittaria fudzinoi Mak. (Classification system Vittaria fudzinoiMakino [V.suberosa Christ]) [nature and flavor] tepor; Micro-hardship; Nontoxic; [return through] liver; Stomach warp; [function cures mainly] regulates the flow of vital energy; Invigorate blood circulation; Pain relieving etc.Radix Clematidis: acrid in the mouth, salty, warm.Return urinary bladder channel.Have but rheumatism, removing obstruction in the collateral to relieve pain, disappear a fishbone or other bone caught in the throat effect.Caulis Lonicerae: sweet in the mouth, cold in nature.GUIXIN, lung, stomach, large intestine channel.There is effect of heat-clearing and toxic substances removing.Fructus Zanthoxyli: acrid in the mouth, temperature.Return spleen, stomach, kidney channel.There is warming middle-JIAO, pain relieving, disinsection efficiency.Rhizoma Atractylodis Macrocephalae (parched), bitter, sweet, warm.Return spleen, stomach warp.There is air making-up and spleen enlivening, dampness diuretic, the effects such as strengthening superficial resistance to stop perspiration.Folium Artemisiae Argyi: acrid in the mouth, bitter, temperature.Return liver,spleen,kidney warp.There is warming the meridian for stopping bleeding, cold expelling regulating menstruation effect.Fructus Schisandrae Chinensis: warm in nature, sour in the mouth, sweet.Return lung, the heart, kidney channel.Be good at convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.The Radix Paeoniae Alba: cool in nature, bitter in the mouth, acid.Enter liver, spleen channel.Be good at nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Radix Panacis Quinquefolii is bitter, micro-sweet, cold.GUIXIN, lung, stomach warp.There is the effect such as tonifying QI to produce body fluid, lung benefiting gas.Rhizoma Zingiberis: hot in nature, acrid in the mouth.Return spleen, stomach, the heart, lung meridian.Be good at warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.Fructus Chaenomelis: sour in the mouth, warm in nature.Return liver, spleen channel.There is collaterals activating, effect of stomach function regulating removing dampness.Radix Saposhnikoviae, pungent, sweet, tepor.Return bladder, liver, spleen channel.There is the effect of expelling pathogenic wind from the body surface.Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.There is warming the meridian for stopping bleeding, cold expelling regulating menstruation effect.([source] is the root stock of the large lotus throne Herba pteridii latiusculi of Angiopteridaceae plant (Angiopteris magna Ching) to Angiopteris magna Ching (Angiopteris majuscula Ching).): nature and flavor are pained, and cold, GUIXIN, lung, large intestine channel, have the effect such as heat-clearing and toxic substances removing, diuresis damp eliminating.Ramulus Cinnamomi: warm in nature, acrid in the mouth, sweet.GUIXIN, lung, urinary bladder channel.Be good at expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian; Activating YANG and prormoting functioning of QI.Herba Lycopodii: bitter in the mouth, pungent, temperature.Return Liver Channel.There is expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral effect.Herba Lysimachiae Klattianae ([source] this product is the dry herb of Ofthe Primulaceae wheel blade Lysimachia christinae Hance Lysimachia klattiana Hance) micro-acid, puckery, cool, there is the effects such as hemostasis, blood pressure lowering.Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Be good at blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Rhizoma Menispermi: bitter, cold.Return lung, stomach, large intestine channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, dampness removing.For laryngopharynx swelling and pain, cough due to lung-heat, mumps, dysentery, jaundice, rheumatic arthralgia, swelling and pain of hemorrhoid, snake bite and insect sting etc.Flos Camelliae Japonicae (Classification system Camelliajaponica L.): nature and flavor are bitter, temperature, returns liver, lung meridian, has effect such as convergence removing heat from blood, hemostasis etc.Herba Ephedrae: warm in nature, acrid in the mouth, micro-hardship.Return lung, urinary bladder channel.Be good at relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema.Scorpio: salty, pungent, flat, returns Liver Channel.Relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.

For compositions of the present invention, according to the prescription compatibility theory of " monarch, minister, help, make ", triangle bubble, Fructus Phoenicis Dactyliferae, Changuienia amoena Chien, Pseudobulbus Pholidotae Chinensis, Folium Rudbeckiae Laciniatae are monarch drug; Sanicle, fragrant Caulis seu Radix Schisandrae Henryi, Semen Sinapis Albae, Bulbus Lilii, Radix Glycyrrhizae, Rhizoma Atractylodis, Flos Farfarae, Vittaria fudzinoi Mak. are ministerial drug; Radix Clematidis, Caulis Lonicerae, Fructus Zanthoxyli, Rhizoma Atractylodis Macrocephalae (parched), Folium Artemisiae Argyi, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Radix Panacis Quinquefolii are adjuvant drug; Rhizoma Zingiberis, Fructus Chaenomelis, Radix Angelicae Sinensis, Angiopteris magna Ching (Angiopteris majuscula Ching), Ramulus Cinnamomi, Herba Lycopodii, Herba Lysimachiae Klattianae, Semen Persicae, Rhizoma Menispermi, Flos Camelliae Japonicae, Herba Ephedrae and Scorpio are for making medicine.All medicines are harmonious in the present invention, reasonable recipe, have determined curative effect, safe ready, have no side effect, cheap feature.

Detailed description of the invention

The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.

Embodiment decoction of the present invention

Take triangle and steep 12 grams, Fructus Phoenicis Dactyliferae 12 grams, Changuienia amoena Chien 15 grams, Pseudobulbus Pholidotae Chinensis 16 grams, Folium Rudbeckiae Laciniatae 12 grams, sanicle 10 grams, fragrant Caulis seu Radix Schisandrae Henryi 10 grams, Semen Sinapis Albae 10 grams, Bulbus Lilii 11 grams, 11 grams, Radix Glycyrrhizae, Rhizoma Atractylodis 11 grams, Flos Farfarae 10 grams, Vittaria fudzinoi Mak. 10 grams, Radix Clematidis 8 grams, Caulis Lonicerae 8 grams, Fructus Zanthoxyli 9 grams, Rhizoma Atractylodis Macrocephalae (parched) 9 grams, Folium Artemisiae Argyi 8 grams, Fructus Schisandrae Chinensis 8 grams, the Radix Paeoniae Alba 8 grams, Radix Panacis Quinquefolii 7 grams, Rhizoma Zingiberis 5 grams, Fructus Chaenomelis 2 grams, Radix Angelicae Sinensis 3 grams, Angiopteris magna Ching (Angiopteris majuscula Ching) 2 grams, Ramulus Cinnamomi 1 gram, Herba Lycopodii 2 grams, Herba Lysimachiae Klattianae 1 gram, 3 grams, Semen Persicae, Rhizoma Menispermi 1 gram, Flos Camelliae Japonicae 2 grams, 1 gram, Herba Ephedrae and Scorpio 1 gram, add 5000 milliliters, water, heating 5 hours under the condition of 90 DEG C of backflows.Filter, filtrate is decoction of the present invention.

Experimental example

Diagnostic criteria:

On the impact of hyperlipidemic mice blood blood fat

Laboratory animal: Kunming mouse, male, body weight 18-22g, purchased from Shanghai Slac Experimental Animal Co., Ltd..

Experimental agents

Take triangle and steep 12 grams, Fructus Phoenicis Dactyliferae 12 grams, Changuienia amoena Chien 15 grams, Pseudobulbus Pholidotae Chinensis 16 grams, Folium Rudbeckiae Laciniatae 12 grams, sanicle 10 grams, fragrant Caulis seu Radix Schisandrae Henryi 10 grams, Semen Sinapis Albae 10 grams, Bulbus Lilii 11 grams, 11 grams, Radix Glycyrrhizae, Rhizoma Atractylodis 11 grams, Flos Farfarae 10 grams, Vittaria fudzinoi Mak. 10 grams, Radix Clematidis 8 grams, Caulis Lonicerae 8 grams, Fructus Zanthoxyli 9 grams, Rhizoma Atractylodis Macrocephalae (parched) 9 grams, Folium Artemisiae Argyi 8 grams, Fructus Schisandrae Chinensis 8 grams, the Radix Paeoniae Alba 8 grams, Radix Panacis Quinquefolii 7 grams, Rhizoma Zingiberis 5 grams, Fructus Chaenomelis 2 grams, Radix Angelicae Sinensis 3 grams, Angiopteris magna Ching (Angiopteris majuscula Ching) 2 grams, Ramulus Cinnamomi 1 gram, Herba Lycopodii 2 grams, Herba Lysimachiae Klattianae 1 gram, 3 grams, Semen Persicae, Rhizoma Menispermi 1 gram, Flos Camelliae Japonicae 2 grams, 1 gram, Herba Ephedrae and Scorpio 1 gram, add 5000 milliliters, water, heating 5 hours under the condition of 90 DEG C of backflows, filter, filtrate is adjusted to concentration and is equivalent to 1.6g crude drug/ml.

Zhibituo, by Chengdu buchu nine, great pharmaceutical factory produces, specification: every dress 0.24g.High lipid food is purchased from Jiangsu Mei Disen biological medicine company limited.

Dosage: the consumption of every mice is: low dose of gavage 0.1ml medicinal liquid, namely dosage and high dose gavage 0.2ml and 0.4ml respectively in, every day every, the medicinal liquid of 20g mouse stomach was respectively 0.16g (low dose group) containing crude drug amount, 0.32g (middle dosage group), 0.64g (high dose group).

Main agents: T-CHOL (TC), triglyceride (TG), highly dense low lipoprotein cholesterol (HDL-C) and low density lipoprotein, LDL (LDL-C) measure test kit, Beijing Zhong Sheng bio-engineering corporation product.

Experimentation: select healthy mice 60, separates 10 as normal group, and all the other 50 mices, raise with high lipid food, normal water, modeling 14d, obtains model group.After model causes, be divided into 5 groups: model group, high dose group, middle dosage group, low dose group, positive drug zhibituo group (340mg/kg), wherein 3 dosage groups, zhibituo groups press above-mentioned dosage gastric infusion, Normal group and model group are to the water of same volume, every morning 1 time, continuous 30d, gets hematometry each Mus TC, TG, HDL-C, LDL-C, each group of data represent with means standard deviation, carry out t test between group.The results are shown in Table 1.

Group

Normal group

Model group

High dose group

Middle dosage group

Low dose group

Zhibituo group

TG(mmol/L)

0.73±0.18

2.76±0.32

1.15±0.21*

1.36±0.13*

1.53±0.16*

1.65±0.27

TC(mmol/L)

1.86±0.25

3.62±0.21

2.13±0.16*

2.42±0.23*

2.71±0.35*

2.89±0.26

HDL-C(mmol/L)

0.81±0.18

1.62±0.27

0.87±0.24*

0.89±0.33*

0.93±0.21*

0.97±0.29

LDL-C(mmol/L)

0.71±0.32

1.25±0.36

0.85±0.27*

0.87±0.31*

0.89±0.28*

0.89±0.16

Note: compare with model group, * p<0.05, indicates significant difference

Conclusion: each dosage of medicament of the present invention all can reduce the blood lipid level of hyperlipidemic mice

Anxious poison experiment

Laboratory animal: Kunming mouse, female 12, male 12, body weight 18 ~ 22g, purchased from Shanghai Slac Experimental Animal Co., Ltd..

Experimental agents:

Experimental procedure:

1. mice adaptability is fed 3 ~ 4 days, and body weight control is within 22g

2. before mice administration, water 12h is can't help in fasting;

3. divide into groups, with random digits table, mice is assigned in blank group and administration group, often organizes 12, male and female half and half.

4. administration, blank group gives normal saline, and administration group gives the medicinal liquid prepared in embodiment, gavage amount 0.25ml/10g.One day twice.

Experimental result: after gavage, mice activity reduces, and loss of appetite, after 24 hours, recovers gradually.After 48 hours, completely normally.Continuous nursing 1 week, abnormal appearance.There is not the phenomenon of dead mouse, general mortality rate 0.According to the experience of Chinese medicine studies on acute toxicity, can think that medicament of the present invention is safe.

Claims

1. the purposes of compositions in the medicament of preparation treatment hyperlipemia, it is characterized in that, described compositions is made up by weight of following bulk drugs: triangle bubble 10-20 part, Fructus Phoenicis Dactyliferae 10-20 part, Changuienia amoena Chien 10-20 part, Pseudobulbus Pholidotae Chinensis 10-20 part, Folium Rudbeckiae Laciniatae 10-20 part, sanicle 10-20 part, fragrant Caulis seu Radix Schisandrae Henryi 10-20 part, Semen Sinapis Albae 10-20 part, Bulbus Lilii 10-20 part, Radix Glycyrrhizae 10-20 part, Rhizoma Atractylodis 10-20 part, Flos Farfarae 10-20 part, Vittaria fudzinoi Mak. 10-20 part, Radix Clematidis 1-10 part, Caulis Lonicerae 1-10 part, Fructus Zanthoxyli 1-10 part, Rhizoma Atractylodis Macrocephalae (parched) 1-10 part, Folium Artemisiae Argyi 1-10 part, Fructus Schisandrae Chinensis 1-10 part, Radix Paeoniae Alba 1-10 part, Radix Panacis Quinquefolii 1-10 part, Rhizoma Zingiberis 1-5 part, Fructus Chaenomelis 1-5 part, Radix Angelicae Sinensis 1-5 part, Angiopteris magna Ching (Angiopteris majuscula Ching) 1-5 part, Ramulus Cinnamomi 1-5 part, Herba Lycopodii 1-5 part, Herba Lysimachiae Klattianae 1-5 part, Semen Persicae 1-5 part, Rhizoma Menispermi 1-5 part, Flos Camelliae Japonicae 1-5 part, Herba Ephedrae 1-5 part and Scorpio 1-5 part.

2. purposes according to claim 1, it is characterized in that, described compositions is made up by weight of following bulk drugs: triangle steeps 12 parts, Fructus Phoenicis Dactyliferae 12 parts, Changuienia amoena Chien 15 parts, Pseudobulbus Pholidotae Chinensis 16 parts, Folium Rudbeckiae Laciniatae 12 parts, sanicle 10 parts, fragrant Caulis seu Radix Schisandrae Henryi 10 parts, Semen Sinapis Albae 10 parts, Bulbus Lilii 11 parts, 11 parts, Radix Glycyrrhizae, Rhizoma Atractylodis 11 parts, Flos Farfarae 10 parts, Vittaria fudzinoi Mak. 10 parts, Radix Clematidis 8 parts, Caulis Lonicerae 8 parts, Fructus Zanthoxyli 9 parts, Rhizoma Atractylodis Macrocephalae (parched) 9 parts, Folium Artemisiae Argyi 8 parts, Fructus Schisandrae Chinensis 8 parts, the Radix Paeoniae Alba 8 parts, Radix Panacis Quinquefolii 7 parts, Rhizoma Zingiberis 5 parts, Fructus Chaenomelis 2 parts, Radix Angelicae Sinensis 3 parts, Angiopteris magna Ching (Angiopteris majuscula Ching) 2 parts, Ramulus Cinnamomi 1 part, Herba Lycopodii 2 parts, Herba Lysimachiae Klattianae 1 part, 3 parts, Semen Persicae, Rhizoma Menispermi 1 part, Flos Camelliae Japonicae 2 parts, 1 part, Herba Ephedrae and Scorpio 1 part.

3. purposes according to claim 1 and 2, is characterized in that, described medicament can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, oral liquid or decoction.