CN109432339A - It is a kind of to treat phthisical Chinese medicine composition - Google Patents
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
Phthisical Chinese medicine composition is treated the present invention provides a kind of, belong to technical field of traditional Chinese medicines, including following raw material composition by weight: spinach fruit 20-60, bletilla striata 12-18, raw tuber of stemona 5-15, oyster plant inflorescence 18-22, phoenix clothing 10-20, foochow perisimmon root 15-35, common nepenthes 10-20；Chinese medicine composition of the invention passes through with lung-heat clearing and detoxification, the drug for the effect of moistening lung to arrest cough is stopped blooding is combined, so that Chinese medicine composition has the generation of interference pulmonary tuberculosis lesion, and has the function of clearing lung-heat moistening lung, reach the phthisical purpose for the treatment of, Chinese medicine composition of the invention, its therapeutic effect is significant, pulmonary tuberculosis can be thoroughly cured, while being avoided using operative treatment bring pain, it is without side-effects after treatment, it is uneasy to recur, and Chinese medicine material easy to operate while selected is easy to get, and cheap.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, especially a kind of to treat phthisical Chinese medicine composition.
Background technique
Tuberculosis is the chronic infectious disease as caused by mycobacterium tuberculosis, can invade many internal organs, be infected with pulmonary Mycobacterium
It is most commonly seen.Excreter is its important infection sources.It not necessarily falls ill after human infection tulase, when resistance reduction or cell
When the allergy of mediation increases, it is likely to cause clinical onset.If can diagnose in time, and rational therapy is given, can obtain and face mostly
Bed recovery from illness, currently used to have drug therapy, operative treatment: the main function of drug therapy is to shorten infective stage, reduce extremely
Die rate, infection rate and illness rate.For each specific patient, then to reach clinical and biology healing major measure, rationally
Change treatment, which refers to, adheres to early stage, combination, appropriate, the regular and whole principle for using sensitive medicaments to active tuberculosis；Surgery
It performs the operation less applied to tuberculosis treatment.To greater than 3 centimetres tuberculoma and lung cancer be difficult to identify when, the unilateral fiber controlled again
Thick wall cavity, long-term medical treatment fail to make the sputum bacteria person of turning out cloudy, or unilateral Alkaline SCGE companion bronchiectasis, loss of function are simultaneously
There are hemoptysis or secondary infection person repeatedly, the lobe of the lung or full pneumonectomy can be made.Tuberculous empyema and (or) bronchopleural fistula are through internal medicine
Treatment it is invalid and accompany side active tuberculosis when, preferably make the lobe of the lung-decortication of the lung.Operative treatment contraindication has: bronchus is glutinous
Film active tuberculosis lesion, and not within excision extension, person's systemic conditions are poor or have the obvious heart, lung, Liver and kidney function incomplete.
Operation is just considered when only drug therapy failure is invalid.Perioperatively patient is without exception will also apply anti-tubercular drug.
The country has research to treat phthisical Chinese medicine preparation at present, and achieves certain effect, such as application number CN
201710094174.2 invention " a kind of for treating the Chinese medicine of pulmonary tuberculosis " discloses 10 parts of the tuber of stemona, 5 parts of bletilla, the root of purple-flowered peucedanum 10
Part, 15 parts of humulus grass, 6 parts of gentianae macrophyllae, 10 parts of the root bark of Chinese wolf-berry.Clinical experiments have proved that the present invention can safely and effectively treat pulmonary tuberculosis.Such as
The invention " a kind of to treat phthisical Chinese medicine composition " of application number CN 201711172394.9 discloses 10-20 parts of Radix Salviae Miltiorrhizae, Huang
Even 10-20 parts, 10-20 parts of rhizoma imperatae, 10-20 parts of rose hip, 5-15 parts of lily, 10-20 parts of bracketplant, 10-20 parts of radices trichosanthis, side
5-15 parts of CedarLeaves, 5-15 parts of antelope's horn, 10-20 parts of the tuber of stemona, 10-20 parts of asparagus fern, 5-15 parts of Radix Notoginseng, 10-20 parts of oxhide gelatin, gentianae macrophyllae
5-15 parts, 5-15 parts of madder, 10-20 parts of Prunella vulgaris, 10-20 parts of honeysuckle, 5-15 parts of dried orange peel, 10-20 parts of ginseng, Radix Glycyrrhizae 5-15
Part.The traditional chinese medicine composition of the invention has effects that consolidate eliminating evil, kidney tonifying benefit lung, and treatment pulmonary tuberculosis is significant in efficacy, reliable effect.
Meanwhile tcm therapy has Small side effects, anti-recurrence rate effect is good, can stablize the state of an illness, indiffusible feature, so that it is in lung knot
Core field has obtained quick application and popularization, and still, since Chinese medicine in the prior art formula is unreasonable, material composition is not proper
When, cause Chinese traditional treatment to be difficult to thoroughly cure pulmonary tuberculosis, and so far not yet discovery can thoroughly cure lung knot in a short time
The Chinese materia medica preparation of core occurs.
Summary of the invention
In order to solve the above technical problems existing in the prior art, the present invention provides that a kind of formula is reasonable, nontoxic secondary makees
With, curative effect it is fast, it is at low cost, can thoroughly cure phthisical Chinese medicine composition.
In order to achieve the above object, the present invention is implemented as follows:
It is a kind of to treat phthisical Chinese medicine composition, including following raw material composition by weight: spinach fruit 20-60,
Bletilla striata 12-18, raw tuber of stemona 5-15, oyster plant inflorescence 18-22, phoenix clothing 10-20, foochow perisimmon root 15-35, common nepenthes 10-20.
Including following raw material composition by weight: spinach fruit 40, the bletilla striata 15, the raw tuber of stemona 10, oyster plant inflorescence 20, phoenix clothing
15, foochow perisimmon root 25, common nepenthes 15.
A kind of preparation method for treating pulmonary tuberculosis Chinese medicine composition, comprising the following steps:
(1) it impregnates: being mixed after raw material is weighed by component, smashing to pieces overflows juice, and ethyl alcohol is added and did not had mixture,
Water bath with thermostatic control is handled, and after recycling ethyl alcohol after 0.8-1.2h, obtains dipping object；
(2) it digests: dipping object being mixed with complex enzyme by the mass ratio of 1:0.3-0.5%, shading room temperature stands 30-
40min obtains zymolyte after raising the temperature to 50 DEG C of progress enzyme deactivations；
(3) acidolysis: zymolyte is mixed with compound acid by the mass ratio of 1:0.2-0.6%, is stirred evenly after standing 1h, and pH is adjusted
It is 6.5-7.5 up to acidolysis object；
(4) dry: after acidolysis object hermetically drying is pulverized, according to different environmental demands be fabricated to tablet, pill,
Capsule, granule, traditional Chinese herbal decoction.
The water bath with thermostatic control, temperature are 38-42 DEG C.
The complex enzyme is to mix amylase, cellulase by the mass ratio of 0.2-0.6:1.
The compound acid, is to be mixed to prepare citric acid, tartaric acid by the mass ratio of 1:1.
A kind of application for treating pulmonary tuberculosis Chinese medicine composition in pulmonary tuberculosis, the composition are applied in pulmonary tuberculosis, phlegm
Middle band blood, haematemesis, afternoon fever, cough.
A kind of application method of Chinese medicine composition in tuberculosis treatment, the Chinese medicine composition, be it is oral, in the morning, afternoon and evening
It respectively takes primary.
In conclusion the beneficial effects of the present invention are: Chinese medicine composition of the invention passes through with lung-heat clearing and detoxification, moistening lung
The drug for the effect of cough-relieving is stopped blooding is combined, so that Chinese medicine composition has the generation of interference pulmonary tuberculosis lesion, and is had
The effect of clearing lung-heat moistening lung reaches the phthisical purpose for the treatment of, and Chinese medicine composition of the invention, therapeutic effect is significant, can be thoroughly
Pulmonary tuberculosis is cured, while being avoided using operative treatment bring pain, it is without side-effects after treatment, it is uneasy to recur, and operate letter
Just, while selected Chinese medicine material is easy to get, and cheap.
Specific embodiment
Specific embodiments of the present invention will be described in further detail below, but the invention is not limited to these realities
Mode is applied, it is claimed to still fall within the claims in the present invention for any improvement or replacement on the present embodiment essence spirit
Range.
Embodiment 1: traditional Chinese herbal decoction
A kind of to treat phthisical Chinese medicine composition, the raw material including following weight proportion is made: spinach fruit 35kg, the bletilla striata
18kg, raw tuber of stemona 12kg, oyster plant inflorescence 22kg, phoenix clothing 10kg, foochow perisimmon root 25kg, common nepenthes 18kg.
(1) it impregnates: being mixed after raw material is weighed by component, smashing to pieces overflows juice, and ethyl alcohol is added and did not had mixture,
Water bath with thermostatic control is handled, and after recycling ethyl alcohol after 0.8h, obtains dipping object；
(2) it digesting: dipping object is mixed with complex enzyme by the mass ratio of 1:0.3%, shading room temperature stands 30min,
Zymolyte is obtained after raising the temperature to 50 DEG C of progress enzyme deactivations；
(3) acidolysis: zymolyte is mixed with compound acid by the mass ratio of 1:0.2%, is stirred evenly after standing 1h, is adjusted pH and is
6.5 up to acidolysis object；
(4) dry: it after acidolysis object hermetically drying is pulverized, is mixed, is decocted twice with after clean filtered through gauze, the
Primary 2 times of the water that raw material weight is added, at a simmer before very hot oven decoct, kept for slight boiling condition 30 minutes after boiling with small fire, with clean
Filtered through gauze obtains medical fluid, spare, and 1.5 times of water of second of addition raw material gross weight in the dregs of a decoction, at a simmer preceding very hot oven decocts, and uses after boiling
Small fire keep slight boiling condition 10 minutes, obtain medical fluid with clean filtered through gauze, will twice medical fluid merge, both Chinese traditional medicine composition of the present invention
Object；It saves, saved in refrigerator cold closet plastic or places at shady and cool ventilation.
Instructions of taking: three times a day, 80 milliliters every time.
Embodiment 2: pill
A kind of to treat phthisical Chinese medicine composition, the raw material including following weight proportion is made: spinach fruit 60kg, the bletilla striata
12kg, raw tuber of stemona 15kg, oyster plant inflorescence 18kg, phoenix clothing 20kg, foochow perisimmon root 15kg, common nepenthes 20kg.
(1) it impregnates: being mixed after raw material is weighed by component, smashing to pieces overflows juice, and ethyl alcohol is added and did not had mixture,
Water bath with thermostatic control is handled, and after recycling ethyl alcohol after 1.2h, obtains dipping object；
(2) it digesting: dipping object is mixed with complex enzyme by the mass ratio of 1:0.5%, shading room temperature stands 40min,
Zymolyte is obtained after raising the temperature to 50 DEG C of progress enzyme deactivations；
(3) acidolysis: zymolyte is mixed with compound acid by the mass ratio of 1:0.6%, is stirred evenly after standing 1h, is adjusted pH and is
7.5 up to acidolysis object；
(4) dry: after acidolysis object hermetically drying is pulverized, honey being put into copper according to the proportional quantities with medicinal powder 1:1
In pot plus boiling is boiled, it is made to dissolve and suitably dilute, and by the sieve of 50 or 65 mesh to filter out impurity, filtrate returns to copper pot relaying
Continuous heating, stirs continuous skimming, occurs when there is the light yellow glossiness uniform thin bubble seethed, twists toughness with hand, when
When two fingers occur when separating without white silk, about 3/4ths medicinal powder is added, ceaselessly stir-frying squeezes, and temperature is high at this time,
Cannot be touched with hand, it is to be mixed at dough after, can try with hand squeeze dough, if feeling to touch with one's hand, just with back up medicinal powder spread
On a bit, continue squeeze beat until tack-free；While hot, it cooks honeyed bolus: dough being twisted into strip, then the use of segment segment
Hand or pocket knife, which are cut down, to be come, with pill plate by 1000 pills are made.
Instructions of taking are as follows: it is oral, it is three times per day, 2-3 each, it is bfore meals.
Embodiment 3: capsule
A kind of to treat phthisical Chinese medicine composition, the raw material including following weight proportion is made: spinach fruit 60kg, the bletilla striata
18kg, raw tuber of stemona 15kg, oyster plant inflorescence 22kg, phoenix clothing 20kg, foochow perisimmon root 35kg, common nepenthes 20kg.
(1) it impregnates: being mixed after raw material is weighed by component, smashing to pieces overflows juice, and ethyl alcohol is added and did not had mixture,
Water bath with thermostatic control is handled, and after recycling ethyl alcohol after 0.8-1.2h, obtains dipping object；
(2) it digesting: dipping object is mixed with complex enzyme by the mass ratio of 1:0.4%, shading room temperature stands 35min,
Zymolyte is obtained after raising the temperature to 50 DEG C of progress enzyme deactivations；
(3) acidolysis: zymolyte is mixed with compound acid by the mass ratio of 1:0.4%, is stirred evenly after standing 1h, and adjusting pH is 7
Up to acidolysis object；
(4) dry: after acidolysis object hermetically drying is pulverized, the auxiliary material medically used is added and is uniformly mixed, sieving,
It is fabricated to capsule 1000.
Instructions of taking are as follows: warm water is swallowed, three times per day, 2-3 each.
Embodiment 4: tablet
A kind of to treat phthisical Chinese medicine composition, the raw material including following weight proportion is made: spinach fruit 20kg, the bletilla striata
12kg, raw tuber of stemona 5kg, oyster plant inflorescence 18kg, phoenix clothing 10kg, foochow perisimmon root 15kg, common nepenthes 10kg.
(1) it impregnates: being mixed after raw material is weighed by component, smashing to pieces overflows juice, and ethyl alcohol is added and did not had mixture,
Water bath with thermostatic control is handled, and after recycling ethyl alcohol after 0.8h, obtains dipping object；
(2) it digesting: dipping object is mixed with complex enzyme by the mass ratio of 1:0.5%, shading room temperature stands 40min,
Zymolyte is obtained after raising the temperature to 50 DEG C of progress enzyme deactivations；
(3) acidolysis: zymolyte is mixed with compound acid by the mass ratio of 1:0.2%, is stirred evenly after standing 1h, is adjusted pH and is
7.5 up to acidolysis object；
(4) dry: after acidolysis object hermetically drying is pulverized, the auxiliary material medically used is added and is uniformly mixed, sieving,
It is in blocks by tablet press machine direct pressing, suppress 1000.
Instructions of taking are as follows: warm water is swallowed, three times per day, each 2-3 piece.
The present invention is nontoxic, takes safety, shows design experiment example to verify the toxicity for treating phthisical Chinese medicine preparation
And effect.
1, toxicity test example:
1.1, material
1.1.1, drug: embodiment 1, the Chinese medicine Chinese medicine composition of embodiment 5 are used.
1.1.2, subjects: small white mouse 50 for choosing physical condition health, half male and half female, weight 10-15g, in people
Work illuminates 12h, breeding observing 3d under ventilation condition good situations, is randomly divided into 5 groups, and 10/group, wherein one group is blank control
Examination group forbids feeding, but can't help water for 4 hours before being administered after 12h and administration.
1.2, method: after 3d, in addition to blank group respectively to other 4 groups of small white mouses gavage dosage be respectively 100ml/kg,
The Chinese medicine composition of the embodiment one of 300ml/kg, 500ml/kg, 700ml/kg observes 7d.
1.3, result: being observed continuously 7d, and the spirit of the strong living and whole small white mouses of whole small white mouses, secretion, is exhaled at appetite
Exception is not observed in suction, eye etc., and by experiment mice and control group mice after analysing, each histoorgan is without obvious sense
Difference, coring, liver, spleen, lung, kidney and intestines make pathological section also without significantly different, increased dosage amount, and same method gavages embodiment
Three Chinese medicine composition, whole mouse are still strong to live, and without exception compared with the control group, illustrates the Chinese medicine Chinese medicine composition to small
Mouse is safe and non-toxic.
2, efficacy test example: the present invention takes safety, easy to operate, significant in efficacy, is that can thoroughly cure phthisical to have
Drug is imitated, and is proved by clinical data, the related clinical data of the present invention is as follows:
2.1 typical cases:
2.1.1, gold so-and-so: 39 years old, male, in March in 2015 5 Nikkei hospital diagnosis suffer from pulmonary tuberculosis, with cough spit blood
Symptom take top 10 pairs after cough, pain symptom disappear, after take after two months pulmonary tuberculosis healing.
2.1.2, Zhang: 45 years old, female, October because pulmonary tuberculosis is hospitalized, with the symptom for fever of spitting blood, opened December
Beginning takes top, checks after 2 months, pulmonary tuberculosis has been cured.
So far, patient body is healthy always for the present inventor's follow-up, and no rebound phenomenon is without exception.
Claims (8)
1. a kind of treat phthisical Chinese medicine composition, which is characterized in that including following raw material composition by weight: spinach
Sub- 20-60, bletilla striata 12-18, raw tuber of stemona 5-15, oyster plant inflorescence 18-22, phoenix clothing 10-20, foochow perisimmon root 15-35, common nepenthes 10-
20。
A kind of treat phthisical Chinese medicine composition 2. as described in claim 1, which is characterized in that including it is following by weight
The raw material of meter forms: spinach fruit 40, the bletilla striata 15, the raw tuber of stemona 10, oyster plant inflorescence 20, phoenix clothing 15, foochow perisimmon root 25, common nepenthes 15.
3. a kind of preparation method for treating pulmonary tuberculosis Chinese medicine composition, which comprises the following steps:
(1) it impregnates: being mixed after raw material is weighed by component, smashing to pieces overflows juice, and ethyl alcohol is added and did not had mixture, constant temperature
Water bath processing obtains dipping object after recycling ethyl alcohol after 0.8-1.2h；
(2) it digests: dipping object being mixed with complex enzyme by the mass ratio of 1:0.3-0.5%, shading room temperature stands 30-40min and is
Can, zymolyte is obtained after raising the temperature to 50 DEG C of progress enzyme deactivations；
(3) acidolysis: zymolyte is mixed with compound acid by the mass ratio of 1:0.2-0.6%, is stirred evenly after standing 1h, is adjusted pH and is
6.5-7.5 up to acidolysis object；
(4) dry: after acidolysis object hermetically drying is pulverized, tablet, pill, capsule being fabricated to according to different environmental demands
Agent, granule, traditional Chinese herbal decoction.
4. a kind of preparation method for treating pulmonary tuberculosis Chinese medicine composition as claimed in claim 3, which is characterized in that the perseverance
Tepidarium, temperature are 38-42 DEG C.
5. a kind of preparation method for treating pulmonary tuberculosis Chinese medicine composition as claimed in claim 3, which is characterized in that described answers
Synthase is to mix amylase, cellulase by the mass ratio of 0.2-0.6:1.
6. a kind of preparation method for treating pulmonary tuberculosis Chinese medicine composition as claimed in claim 3, which is characterized in that described answers
Nitration mixture is to be mixed to prepare citric acid, tartaric acid by the mass ratio of 1:1.
7. a kind of application for treating pulmonary tuberculosis Chinese medicine composition in pulmonary tuberculosis, which is characterized in that the composition is applied
Pulmonary tuberculosis, blood-stained sputum, haematemesis, afternoon fever, cough.
8. a kind of application method of Chinese medicine composition in tuberculosis treatment, which is characterized in that the Chinese medicine composition is mouth
Clothes are respectively taken primary in the morning, afternoon and evening.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811360457.8A CN109432339A (en) | 2018-11-15 | 2018-11-15 | It is a kind of to treat phthisical Chinese medicine composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811360457.8A CN109432339A (en) | 2018-11-15 | 2018-11-15 | It is a kind of to treat phthisical Chinese medicine composition |
Publications (1)
| Publication Number | Publication Date |
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| CN109432339A true CN109432339A (en) | 2019-03-08 |
Family
ID=65552911
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811360457.8A Withdrawn CN109432339A (en) | 2018-11-15 | 2018-11-15 | It is a kind of to treat phthisical Chinese medicine composition |
Country Status (1)
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260207A (en) * | 1999-11-30 | 2000-07-19 | 王占武 | Medicinal powder for pulmonary tuberculosis |
-
2018
- 2018-11-15 CN CN201811360457.8A patent/CN109432339A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260207A (en) * | 1999-11-30 | 2000-07-19 | 王占武 | Medicinal powder for pulmonary tuberculosis |
Non-Patent Citations (1)
| Title |
|---|
| 金贵善: "《3000个家庭自诊自疗方》", 31 January 2008, 延边大学出版社 * |
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Application publication date: 20190308 |
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