CN109700966A - A kind of drug that treating hepatitis B, preparation method and applications - Google Patents
A kind of drug that treating hepatitis B, preparation method and applications Download PDFInfo
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Abstract
The invention belongs to treating hepatitis B technical field of pharmaceuticals, a kind of drug for treating hepatitis B, preparation method and applications are disclosed, the part monarch drug in a prescription of the drug of the treatment hepatitis B and the parts by weight of ministerial drug are as follows: seven 140-160 parts of bamboo root, 80-120 parts of polygonum cill, seven 40-60 parts of cattle heart, 140-160 parts of the coptis, 180-220 parts of Prunella vulgaris, 180-220 parts of polygonum cuspidate, 180-220 parts of the root bark of Chinese wolf-berry, 280-320 parts of cape jasmine, 280-320 parts of radix paeoniae rubra, 280-320 parts of radix scutellariae, seven 380-420 parts of conch and 180-220 parts of folium isatidis.It is an advantage of the current invention that the drug of the treatment hepatitis B is fast to hepatitis B big and small three Yang patient's negative conversion rate but not damaged to liver cell and kidney, it is unchanged to liver function normal value, wholistic therapy expense is low, good effect, is a kind of green medicine, alleviates medical burden for most of hepatitis B patients.
Description
Technical field
The invention belongs to treating hepatitis B technical field of pharmaceuticals, and in particular to a kind of drug for treating hepatitis B, preparation method and
It is applied.
Background technique
Liver is an organ in body based on metabolic function, manufactures the bile in digestive system, and in body
Face plays the effects of deoxidation, storage glycogen and synthesis secreted protein.Liver is to ex vivo and external many non-battalion
For example various drugs of substance of nourishing one's nature, poisonous substance and internal certain metabolites, have biotransformation.By metabolism by it
Thoroughly decompose or excreted with original shape.This effect is also referred to as " function of detoxification ", and certain poisonous substances pass through bioconversion, can
It is smaller to be changed into nontoxic or toxicity, it is easy to the substance drained.Under normal circumstances, liver synthesis and secretion bile, and then synthesize
A variety of coagulation factors, and when liver is damaged, will cause multiple functions obstacle, body can also occur therewith jaundice, bleeding,
Infection, renal dysfunction even hepatic encephalopathy.
Hepatitis B is the B-mode class of virus hepatitis, belongs to Hepadnaviridae, is caused by hepatitis B (HBV).The morning of hepatitis B
Phase symptom has: the symptoms such as out of strength, tired, anorexia, Nausea and vomiting, skin yellowing, grade fever, insomnia, dreaminess.These are all
Hepatitis B virus infection liver cell causes Symptoms caused by hepatocellular injury.It there will be severe dysfunction of liver, hepatopathy
Face, show as complexion it is dim it is black, it is yellowish-brown it is simple and unadorned, coarse, lip color is dark violet etc.；Face telangiectasis, spider angioma can also be caused
And the important feature of the initial stages hepatopathy such as liver palms.There are three kinds of forms, such as hepatitis B surface antigen in human serum for hepatitis B
HBsAg, hepatitis B core antibody HBc and hepatitis B virus e antigen (HBeAg), wherein detecting three positives, as common great three positive.e
Antibody (anti-HBe) is positive, and positive core antigen (HBcAg) is "small three positive".It is indicated with simple surface antigen and the surface antibody positive
Patient is in hepatitis B convalescence, indicates that patient is in hepatitis B acute stage and chronic phase hepatitis with core antigen and core antibody positive
Acute attack, e antigen and e antibody positive indicate that Chronic height infects the phase, but infectiousness is low.After hepatitis B invades human body,
It is mainly replicated in liver cell, damage liver cell causes liver cell hardening to be then converted into liver cancer.Hepatitis B chronic infection is divided into four
Stage: i.e. immune tolerance, immune clearance phase, nonmobile phase and active period.Hepatitis B pathological manifestations are with the denaturation of liver cell diffusivity
Necrosis, while the inflammatory cell infiltration different with degree, interstitial proliferation and liver cell regeneration.The circulation way of hepatitis B has
Heredity, blood and shared injection needle.
It is costly, effect is poor and can not much cure currently, the common western modern medicine for the treatment of hepatitis B, Long-term taking medicine is needed,
Biggish economic pressures and stress are brought to patient.Due to the features described above of hepatitis B, many patients are normal in daily life
Because face have it is different by certain discrimination, if after making a definite diagnosis, can also be to the work of patient since it cures difficult, infectivity characteristic
Make, life even marriage causes large effect.
Therefore, it is badly in need of developing a kind of new therapeutic agent, to overcome drawbacks described above.
Summary of the invention
In order to solve the above problems existing in the present technology, it is low, eutherapeutic that it is an object of that present invention to provide a kind of expenses
The drug of hepatitis B is treated, while additionally providing the preparation method and applications of the drug.
The technical scheme adopted by the invention is as follows:
For inventor as Chinese medicine worker, it is more to encounter hepatitis B patient in clinic, deeply understands that many hepatitis B patients exist
Because of inconvenience and pain caused by hepatitis B in life and work, inventor utilizes the tcm knowledge of oneself and facing for many years
Bed working experience has developed the drug of the treatment hepatitis B for the Chinese medicine onset theory of hepatitis B.
Raw material used in the drug for the treatment of hepatitis B provided by the invention is as follows:
The effect of Rhizoma Trillii Tschonoskii: for the meat taproot of Araliaceae Panax major, having tonifying middle-Jiao and Qi, and myogenic is put on flesh.Property
It is sweet in flavor acrid in flavour and warm in nature.Can wind-dispelling, relax liver, invigorate blood circulation, hemostasis.For hypertension, giddy is had a headache, injury and bone fracture, lumbocrural pain, and wound goes out
Blood.
Bamboo root seven: kidney fire is rushed down in the evergreen bamboo root seven of alias Song Shoulan, leaflet or ophiruid seven, moistening lung to arrest cough, wind-dispelling, enriching yin.
Radix scrophulariae: alias radix scrophulariae, Zhejiang radix scrophulariae, black ginseng, weight platform, ghost hiding or positive horse, clearing heat and cooling blood, nourishing yin and lessening fire, detoxicating and resolving a mass,
It rushes down to swim and reach.
Radix Ophiopogonis: for the dried root of liliaceous plant Radix Ophiopogonis, nature and flavor are sweet, slight bitter, slightly cold.Return heart, lung, stomach meridian.It can yin-nourishing
It promotes the production of body fluid, moistening lung and clearing away the heart-fire.For dryness of the lung dry cough, consumptive disease is coughed, larynx numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, and intestinal dryness is just
It is secret.
Fructus lycii: for the dry mature fruit of Lycium barbarum L. of solanaceae, nature and flavor sweet and neutral.Return liver and kidney channel.It can nourish
Liver kidney, benefiting shrewd head.For consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, impotence and seminal emission, Heat Diabetes, blood deficiency chlorosis, blurred vision
It is unknown.
Polygonum cill: alias airpotato yam, buckwheat steamed bun or Ciliatenerve Knotweed Root.Bitter, cool in nature, mild toxicity.Promoting blood circulation and hemostasis, regulating qi-flowing for relieving pain, clearly
Thermal detoxification.
Cattle heart seven: belonging to one of seven medicine class of Shaanxi, is Shaanxi one with herbal medicine known to people.Also known as Oreas martiana(Hopp. Et Hornsch.) Brid.
The coptis: the dry rhizome of the Mao Moke plant coptis, the triangle leaf coptis or cloud even, it is bitter in taste, it trembles with fear.Return heart, spleen, stomach,
Liver, gallbladder, large intestine channel.Can heat-clearing and damp-drying drug, purging fire for removing toxin.For damp and hot feeling of fullness, acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, the heart are vomitted
Fiery Kang Sheng, dysphoria and insomnia, palpitation and uneasiness, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells furunculosis；Eczema, wet sore, ear canal are controlled outside
It suppurates.
Radix Rehmanniae: alias radix rehmanniae recen, wild country Huang or mountain cigarette root etc..With heat-clearing, promotes the production of body fluid, moisturizes, is laxation, broken stasis of blood, raw new, only
Bitterly, menstruation regulating, the effect of the metal-inflicted wound stasis of blood, cool blood and hemostasis.
The shell of seaear: for the shell of Bao Ke animal Haliotis diversicolor, haliotis discus hannai Ino, sheep Bao, haliotis ruber, Er Bao or white Bao, nature and flavor are salty,
It is cold.Return liver warp.Can be calming the liver, it clears liver and improve vision.For headache and dizziness, cataract, blurring of vision, optic atrophy night blindness.
Cortex Phellodendri: also known as bark of a cork tree wood or cork tree wood etc., bitter is cold in nature.It is clearing heat and detoxicating, purging intense heat eliminating dampness.Cure mainly acute bacterial dysentery
The inflammation such as disease, chordapsus, acute icteric hepatitis, urinary system infection contamination.Burning hot wound, tympanitis, acute conjunctivitis are controlled in external application
Deng.
Rhizoma anemarrhenae: herbaceos perennial, Bie Cheng Ant-eggs it is female, even female, wild knotweed, ground ginseng, bitter trembles with fear, and enters lung, stomach, kidney channel.Enriching yin
Fall fire, moisturizing dryness and lubricating intestine.It controls dysphoria with smothery sensation to quench one's thirst, hectic fever due to yin labor heat, cough with lung heat, dry feces, difficult urination.
Prunella vulgaris: for the drying fruit ear of Lamiaceae plant Prunella vulgaris.Nature and flavor are pungent, bitter, tremble with fear.Return liver, gallbladder channel.It can clear liver and rush down
Fire, improving eyesight, mass dissipating and swelling eliminating.For red eye, swell pain, eyeball night pain, headache and dizziness, scrofula, goiter, acute mastitis, breast illness, swollen breasts.
Chinese mahonia: the drying stem of Berberidaceae plant mahonia bealei or mahonia fortuneiFedde.It is bitter in taste, it trembles with fear.Return liver,
Stomach, large intestine channel.The hot eliminating dampness of Ke Cheongju, purging fire for removing toxin.For damp-heat dysentery, yellow subcutaneous ulcer urinates red, red eye, swell pain, gastropyretic toothache, sore cloth carbuncle
It is swollen.
Radix Curcumae: for zingiberaceous plant RADIX CURCUMAE, turmeric, Guangxi justice art or zedoary dried root.Nature and flavor are pungent, bitter, tremble with fear.Return
Liver, the heart, lung channel.Can promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood, normalizing gallbladder to cure jaundice.For pricking pain in the chest, chest impediment and cardialgia, menostasis pain
Through, swollen breasts, pyreticosis coma, epilepsy is gone mad, blood-head tells nosebleed, jaundice and reddish urine.
Polygonum cuspidate: for the dry rhizome and root of few section's plant polygonum cuspidatum.Nature and flavor slight bitter, it is slightly cold.Return liver, gallbladder, lung channel.Can dampness removing move back
Huang, clearing heat and detoxicating, removing blood stasis and acesodyne is relieving cough and reducing sputum.For jaundice with damp-heat pathogen, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, extreme misery scalds
Wound, menostasis , Disorder lump in the abdomen, traumatic injury, cough with lung heat.
The root bark of Chinese wolf-berry: alias Chinese wolfberry skin is Solanaceae, Lycium, is the root skin of fructus lycii.It can be used as medicine, have and bring down a fever except steaming
The benefits of, cool blood rushes down the fire in gas except steaming, clearing lung-heat fall fire and other effects.
Cape jasmine: for the dry mature fruit of Juncao section plant cape jasmine.It is bitter in taste, it trembles with fear.Return heart, lung, tri-jiao channel.Can purging intense heat remove
It is tired, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body；Externally used detumescence analgesic.For Vexed, jaundice with damp-heat pathogen, the puckery pain of stranguria, blood-head tells nosebleed, mesh
Red swelling and pain, pathogenic fire,toxin and furuncles；Bruise pain is controlled outside.
Radix paeoniae rubra: for ranunculaceae plant Chinese herbaceous peony or the dry root of river radix paeoniae rubra.It is bitter in taste, it is slightly cold.Return liver warp.Can clearing heat and cooling blood,
Removing blood stasis and acesodyne.For thermal man's ying blood, febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, amenorrhea and algomenorrhea , abdominal mass and abdominal pain,
Injury from falling down, carbuncle swells sore.
Radix scutellariae: alias Radix Scutellariae, tsuchikane tea root are lamiaceae labiatae scutellaria herbaceos perennials.Root is used as medicine, bitter, property
It is cold, there are heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention and other effects.
Fingered citron: for the dry fruit of rutaceae fingered citron.Nature and flavor are pungent, bitter, sour, temperature.Liver, spleen, stomach, lung is returned to unravel silk.It can dredge
Liver and qi and Helmet analgesic, it is eliminating dampness and eliminating phlegm.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting, coughing with a lot of sputum.
Conch seven: alias paris polyphylla, paris polyphylla, Chi stop, weight platform root, it is whole stop, careless river vehicle, weight platform grass, Bai Gansui, gold thread
Paris polyphylla, worm beach wormwood, nine hoops, mandarin duck worm or branch fresh idea swell and ache for furunculosis, abscess of throat, snakebite and bugbite, the pain of injury caused by falling and tumbling, infantile convulsion
Twitch.
Bittersweet: for Solanaceae herbaceous species.Board wind rattan.It is sweet, bitter, it trembles with fear.It is clearing heat and detoxicating, expelling wind and removing dampness, stagnation resolvation.For damp and hot Huang
Subcutaneous ulcer, rheumatic arthritis, vaginal discharge diseases, oedema, stranguria, erysipelas, furunculosis, carcinoma.
Folium isatidis: for the dried leaf of cruciferae isatis.It is bitter in taste, it trembles with fear.Return heart, stomach meridian.Can be clearing heat and detoxicating, cool blood
Ecchymose removing.For warm disease high fever, coma, spot dermexanthesis makees the cheek, sore throat, erysipelas, carbuncle swells.
Honeysuckle: clearing heat and detoxicating.
Fructus Forsythiae: heat-clearing, removing toxic substances, dissipating bind, detumescence.Control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.
Oriental wormwood: for the dry aerial parts that compositae plant shore is high or oriental wormwood is high.It is bitter in taste, pungent, it is slightly cold.Returns spleen, stomach, liver,
Gallbladder channel.Can eliminating dampness and heat, normalizing gallbladder to cure jaundice.For jaundice oliguria, damp-warm syndrome summer-heat and damp, wet sore.
Radices trichosanthis: for cucurbitaceous plant snakegourd or the bilateral dry root for including building.Nature and flavor are sweet, bitter, slightly cold.It attaches to the lung and stomach meridians.It can
Clearing heat-fire promotes the production of body fluid to quench thirst, detumescence and apocenosis.For pyreticosis and polydipsia, lung-heat type cough, Heat Diabetes, sore swollen toxin.
Dandelion: for compositae plant dandelion, dandelion or the drying herbs of several plants is belonged to alkali.It is bitter in taste, sweet,
It is cold.Return liver, stomach meridian.Can be clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung
Carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
Cockchafer lotus: also known as: white taste lotus, She Lian.Hardship is trembled with fear, slightly poisonous.
Pulp of dogwood fruit: for the drying and ripening pulp of mountain Lai Yingke plant mountain Lay English.Nature and flavor acid, puckery, tepor.Return liver, kidney.It can mend
Liver and kidney benefiting, arresting collape syndrome by astringents.For dizziness and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, metrorrhagia and metrostaxis leukorrhagia, profuse sweating is collapsed, interior
Heat is quenched one's thirst.
Ground gallbladder: also known as Du Long, green rainbow.It is pungent, it trembles with fear, it is toxic.Poison is attacked, by the stasis of blood.Malignant sore, nasal polyp are controlled in external application；Internal treatment of scrofula.
Rhizoma Chuanxiong: also known as poor, rhizome of chuanxiong Qiong, fragrant fruit, Hu Qiong and rhizome of chuanxiong Qiong etc. are brought up in mountain, have effects that blood-activating and qi-promoting and wind-expelling pain-stopping.
It can be used for pacifying nerve, treat cold and headache, abdominal mass abdominal pain, pricking pain in the chest, tumbling and swelling, headache, rheumatic arthralgia.
Radix Isatidis: for the dry root of crucifer Song indigo plant.It is bitter in taste, it trembles with fear.Return heart, stomach meridian.Can be clearing heat and detoxicating, cool blood
Relieving sore-throat.It is malicious when for warm epidemic disease, pharyngalgia of generating heat, febrile virulent maculae, mumps, scarlet fever, major part pestilence, erysipelas, carbuncle swells.
Field pennycress: alias Chinese ixeris herb, Chinese Ixeris, Jie Tuolian, small bitter wheat dish.Nature and flavor: acrid flavour, hardship, it is slightly cold.Return liver, stomach, large intestine
Through.It is clearing heat and detoxicating, cool blood, the carbuncle that disappears apocenosis, stasis-dispelling and pain-killing.
Radix gentianae: for the dry aerial parts of compositae plant Artemisia santonica.It is bitter in taste, it trembles with fear.Return lung, Liver Channel.Can clearing heat and eliminating phlegm, only
Cloperastine asthma, detoxification and promoting urination, cooling blood and hemostasis.For cough with lung heat, abundant expectoration is panted, pharyngalgia, aphtha, jaundice with damp-heat pathogen, bleeding from five sense organs or subcutaneous tissue, hematochezia,
Metrorrhagia and metrostaxis, traumatic hemorrhage.
The seed of feather cockscomb: for the dry mature seed of amaranthaceous plant feather cockscomb.It is bitter in taste, it is slightly cold.Return liver warp.Can clearing liver-fire, it is bright
Mesh moves back screen.For the hot hot eyes of liver, raw screen film of mesh, blurring of vision, hepatopyretic vertigo.
Radix ampelopsis: for the dried root of vitaceae radix ampelopsis.It is bitter in taste, it is slightly cold.Return heart, helmet warp.Can be clearing heat and detoxicating, disappear carbuncle
Dissipating bind, expelling pus and promoting granulation.For ulcer carbuncle on the back, furunculosis, scrofula, burn and scald.
Radix Angelicae Sinensis: taste sweet, warm.Return liver, the heart and the spleen channel.It can enrich blood, invigorate blood circulation, menstruction regulating and pain relieving and moisturizing dryness and lubricating intestine.It is all to cure mainly the deficiency of blood
Card, irregular menstruation, menostasis, dysmenorrhea, abdominal mass knot are poly-, metrorrhagia and metrostaxis, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness, intestines are dry and shit is difficult, weight after dysentery with bloody stool,
Ulcer sores and injury from falling down.
Rhizoma Atractylodis Macrocephalae: for the dry rhizome of compositae plant Rhizoma Atractylodis Macrocephalae.Bitter in taste, sweet, warm.Returns spleen, stomach meridian.Can Jian spleen QI invigorating, eliminating dampness
Li Shui, hidroschesis, miscarriage prevention.For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema spontaneous perspiration, threatened abortion.
Cortex moutan: for the dry root skin of ranunculaceae peony.It is bitter in taste, pungent, it is slightly cold.Return heart, liver and kidney channel.It can heat-clearing
Cool blood, activating microcirculation and removing stasis medicinal.For thermal man's ying blood, febrile virulent maculae, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to yin, amenorrhea and algomenorrhea falls and flutters
The pain of injury, carbuncle sore tumefacting virus.
Radix bupleuri: for the dry root of umbelliferae bupleurum or radix bupleuri scorzoneraefolii.Nature and flavor are pungent, bitter, slightly cold.Return liver, gallbladder, lung channel.
It can evacuate and bring down a fever, soothing liver-qi stagnation, lifting disease.For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, uterus takes off
It hangs down, rectal prolapse.
Green peel: for the pericarp of the drying young fruit or immature fruit of rutaceae bridge and its variety.Property hide it is bitter,
It is acrid in flavour and warm in nature, return liver, gallbladder, stomach meridian.Can soothing the liver relieving stagnant Qi, disperse accumulationization is stagnant.For distending pain in the chest and hypochondrium, hernia pain, breast illness, acute mastitis, dyspepsia gas
It is stagnant, abdominal distention.
Chinese yam: splenasthenic diarrhea, frequent urination, the diseases such as indigestion are used for.It also can help to the digestion and absorption of stomach and intestine.To slow
Property esophagitis, gastritis, gastric and duodenal ulcer, chronic pancreatitis and the bad equal diseases person of Small Intestinal have auxiliary well
Help therapeutic effect.
Radix Salviae Miltiorrhizae: for the dry root and rhizome of Lamiaceae plant Radix Salviae Miltiorrhizae.Containing tanshinone, it is robustness emmenagogue, there is dissolving stasis, life
Newly, the effectiveness such as promoting blood circulation and menstruation regulating are gynaecology's key medicine, cure mainly uterine hemorrhage, irregular menstruation, blood stasis, abdominal pain, dysmenorrhoea, menostasis, mausoleum
Bitterly.There is good result to treatment coronary heart disease.Furthermore the weak insomnia of nerve, arthralgia, anaemia, mazoitis, lymph gland can also be controlled
Inflammation, arthritis, boil pain is swollen, erysipelas, acute, chronic hepatitis, nephropyelitis, traumatic injury.External application can wash dermatitis rhus again.
Asian puccoon: for the dry root of comfrey lithospermum euchromum Royle or arnebia guttata Bunge.Nature and flavor are sweet, salty, tremble with fear.Converge to heart and liver channels.It can
Clearing heat and cooling blood, promoting blood circulation and detoxication, promoting eruption ecchymose removing.For blood-heat and toxin exuberance, atropurpureus macula, measles without adequate eruption, sore, eczema, scald.
Ginseng: being the root with meat, medicinal.It can be used for restoring more afterwards, enhance physical strength, adjust hormone, reduce blood glucose
With control blood pressure, control liver index and liver function health care etc..
Radix Astragali: alias silk floss stilbene, astragalus, only mulberry have the effect of invigorating qi, consolidating exterior, promoting urination and detoxification, apocenosis, expelling pus and promoting granulation.
Based on this, technical solution of the present invention is announced as follows:
A kind of drug for treating hepatitis B, is mainly prepared by the raw material of following parts by weight: 140-160 parts of Rhizoma Trillii Tschonoskii, bamboo
Seven 140-160 parts of root, 140-160 parts of radix scrophulariae, Radix Ophiopogonis 140-160 part, 180-220 parts of fructus lycii, 80-120 parts of polygonum cill, cattle heart
Seven 40-60 parts, 140-160 parts of the coptis, 380-420 parts of Radix Rehmanniae, 280-320 parts of the shell of seaear, 280-320 parts of Cortex Phellodendri, rhizoma anemarrhenae 280-
320 parts, 180-220 parts of Prunella vulgaris, 280-320 parts of Chinese mahonia, 80-120 parts of Radix Curcumae, 180-220 parts of polygonum cuspidate, root bark of Chinese wolf-berry 180-
220 parts, 280-320 parts of cape jasmine, 280-320 parts of radix paeoniae rubra, 280-320 parts of radix scutellariae, 80-120 parts of fingered citron, seven 380-420 parts of conch,
80-120 parts of bittersweet, 180-220 parts of folium isatidis, 380-420 parts of honeysuckle, 380-420 parts of Fructus Forsythiae, 180-220 parts of oriental wormwood, smallpox
140-160 parts of powder, 280-320 parts of dandelion, 80-120 parts of cockchafer lotus, 280-320 parts of pulp of dogwood fruit, 80-120 parts of gallbladder, Rhizoma Chuanxiong
180-220 parts, it is 280-320 parts of Radix Isatidis, 180-220 parts of field pennycress, 280-320 parts of radix gentianae, 280-320 parts of the seed of feather cockscomb, white
180-220 parts of liana, 280-320 parts of Radix Angelicae Sinensis, 140-160 parts of Rhizoma Atractylodis Macrocephalae, 280-320 parts of cortex moutan, 280-320 parts of radix bupleuri, green peel 80-
120 parts, 80-120 parts fragrant logical, 180-220 parts of Chinese yam, 280-320 parts of Radix Salviae Miltiorrhizae, 280-320 parts of Asian puccoon, 380-420 parts of ginseng and
380-420 parts of Radix Astragali.
Preferably, the drug of above-mentioned treatment hepatitis B, is mainly prepared by the raw material of following parts by weight: 150 parts of Rhizoma Trillii Tschonoskii,
7 150 parts of bamboo root, 150 parts of radix scrophulariae, 150 parts of Radix Ophiopogonis, 200 parts of fructus lycii, 100 parts of polygonum cill, 7 50 parts of cattle heart, 150 parts of the coptis,
400 parts of Radix Rehmanniae, 300 parts of the shell of seaear, 300 parts of Cortex Phellodendri, 300 parts of rhizoma anemarrhenae, 200 parts of Prunella vulgaris, 300 parts of Chinese mahonia, Radix Curcumae 100
Part, 200 parts of polygonum cuspidate, 200 parts of the root bark of Chinese wolf-berry, 300 parts of cape jasmine, 300 parts of radix paeoniae rubra, 300 parts of radix scutellariae, 100 parts of fingered citron, 7 400 parts of conch,
100 parts of bittersweet, 200 parts of folium isatidis, 400 parts of honeysuckle, 400 parts of Fructus Forsythiae, 200 parts of oriental wormwood, 150 parts of radices trichosanthis, dandelion 300
Part, 100 parts of cockchafer lotus, 300 parts of pulp of dogwood fruit, 100 parts of gallbladder, 200 parts of Rhizoma Chuanxiong, 300 parts of Radix Isatidis, 200 parts of field pennycress, radix gentianae
300 parts, 300 parts of the seed of feather cockscomb, 200 parts of radix ampelopsis, 300 parts of Radix Angelicae Sinensis, 150 parts of Rhizoma Atractylodis Macrocephalae, 300 parts of cortex moutan, 300 parts of radix bupleuri, green peel 100
Part, fragrant 100 parts logical, 200 parts of Chinese yam, 300 parts of Radix Salviae Miltiorrhizae, 300 parts of Asian puccoon, 400 parts of ginseng and 400 parts of Radix Astragali.
Preferably, the drug of above-mentioned treatment hepatitis B, it is described treatment treatment hepatitis B drug dosage form be tablet, capsule or
Pill.
A kind of preparation method of drug that treating hepatitis B, includes the following steps: each raw material for weighing drug above-mentioned according to quantity,
Impurity is removed, each raw material after removal impurity is crushed, is mixed to get the drug of the treatment hepatitis B is arrived.
It is a kind of it is above-mentioned treatment hepatitis B drug preparation treatment hepatopathy drug in application.
Specifically, the hepatopathy is hepatitis B.
Specifically, the hepatopathy is positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B.
Specifically, the hepatopathy is hepatitis B "small three positive".
The invention has the benefit that
The drug for the treatment of hepatitis B provided by the invention is fast but lossless to liver cell to hepatitis B big and small three Yang patient's negative conversion rate
Wound, unchanged to liver function normal value and do not damage renal function, it is a kind of green medicine that wholistic therapy expense is low, good effect
Product alleviate medical burden for most of hepatitis B patients.
Specific embodiment
Further explaination is done to the present invention combined with specific embodiments below.
Embodiment 1:
The purpose of the present embodiment is that providing a kind of drug for treating hepatitis B, preparation method is as follows:
It is as follows that each raw material is weighed according to quantity: Rhizoma Trillii Tschonoskii 140g, seven 140g of bamboo root, radix scrophulariae 140g, Radix Ophiopogonis 140g, fructus lycii
180g, polygonum cill 80g, seven 40g of cattle heart, coptis 140g, Radix Rehmanniae 380g, shell of seaear 280g, Cortex Phellodendri 280g, rhizoma anemarrhenae 280g, summer are withered
Careless 180g, Chinese mahonia 280g, Radix Curcumae 80g, polygonum cuspidate 180g, root bark of Chinese wolf-berry 180g, cape jasmine 280g, radix paeoniae rubra 280g, radix scutellariae 280g, Buddhist
Hand 80g, seven 380g of conch, bittersweet 120g, folium isatidis 220g, honeysuckle 380g, Fructus Forsythiae 380g, oriental wormwood 180g, radices trichosanthis 140g,
Dandelion 280g, cockchafer lotus 80g, pulp of dogwood fruit 280g, gallbladder 80g, Rhizoma Chuanxiong 180g, Radix Isatidis 280g, field pennycress 180g, radix gentianae
280g, seed of feather cockscomb 280g, radix ampelopsis 220g, Radix Angelicae Sinensis 280g, Rhizoma Atractylodis Macrocephalae 160g, cortex moutan 280g, radix bupleuri 280g, green peel 80g, perfume are logical
80g, Chinese yam 180g, Radix Salviae Miltiorrhizae 280g, Asian puccoon 280g, ginseng 380g and Radix Astragali 420g remove impurity, by each original after removal impurity
Feed powder is broken, mixes to get the drug of the treatment hepatitis B is arrived.
Embodiment 2:
The purpose of the present embodiment is that providing a kind of drug for treating hepatitis B, preparation method is as follows:
It is as follows that each raw material is weighed according to quantity: Rhizoma Trillii Tschonoskii 150g, seven 150g of bamboo root, radix scrophulariae 150g, Radix Ophiopogonis 150g, fructus lycii
200g, polygonum cill 100g, seven 50g of cattle heart, coptis 150g, Radix Rehmanniae 400g, shell of seaear 300g, Cortex Phellodendri 300g, rhizoma anemarrhenae 300g, summer are withered
Careless 200g, Chinese mahonia 300g, Radix Curcumae 100g, polygonum cuspidate 200g, root bark of Chinese wolf-berry 200g, cape jasmine 300g, radix paeoniae rubra 300g, radix scutellariae 300g,
Fingered citron 100g, seven 400g of conch, bittersweet 100g, folium isatidis 200g, honeysuckle 400g, Fructus Forsythiae 400g, oriental wormwood 200g, radices trichosanthis
150g, dandelion 300g, cockchafer lotus 100g, pulp of dogwood fruit 300g, gallbladder 100g, Rhizoma Chuanxiong 200g, Radix Isatidis 300g, field pennycress
200g, radix gentianae 300g, seed of feather cockscomb 300g, radix ampelopsis 200g, Radix Angelicae Sinensis 300g, Rhizoma Atractylodis Macrocephalae 150g, cortex moutan 300g, radix bupleuri 300g, blueness
Skin 100g, fragrant logical 100g, Chinese yam 200g, Radix Salviae Miltiorrhizae 300g, Asian puccoon 300g, ginseng 400g and Radix Astragali 400g, remove impurity, will remove
Each raw material after impurity crushes, and mixes to get the drug of the treatment hepatitis B is arrived.
Embodiment 3:
The purpose of the present embodiment is that providing a kind of drug for treating hepatitis B, preparation method is as follows:
It is as follows that each raw material is weighed according to quantity: Rhizoma Trillii Tschonoskii 160g, seven 160g of bamboo root, radix scrophulariae 160g, Radix Ophiopogonis 160g, fructus lycii
220g, polygonum cill 120g, seven 60g of cattle heart, coptis 160g, Radix Rehmanniae 420g, shell of seaear 320g, Cortex Phellodendri 320g, rhizoma anemarrhenae 320g, summer are withered
Careless 220g, Chinese mahonia 320g, Radix Curcumae 120g, polygonum cuspidate 220g, root bark of Chinese wolf-berry 220g, cape jasmine 320g, radix paeoniae rubra 320g, radix scutellariae 320g,
Fingered citron 120g, seven 420g of conch, bittersweet 80g, folium isatidis 180g, honeysuckle 420g, Fructus Forsythiae 420g, oriental wormwood 220g, radices trichosanthis
160g, dandelion 320g, cockchafer lotus 120g, pulp of dogwood fruit 320g, gallbladder 120g, Rhizoma Chuanxiong 220g, Radix Isatidis 320g, field pennycress
220g, radix gentianae 320g, seed of feather cockscomb 320g, radix ampelopsis 180g, Radix Angelicae Sinensis 320g, Rhizoma Atractylodis Macrocephalae 140g, cortex moutan 320g, radix bupleuri 320g, blueness
Skin 120g, fragrant logical 120g, Chinese yam 220g, Radix Salviae Miltiorrhizae 320g, Asian puccoon 320g, ginseng 420g and Radix Astragali 380g, remove impurity, will remove
Each raw material after impurity crushes, and mixes to get the drug of the treatment hepatitis B is arrived.
Side's solution, drug taste and edible taboo of the drug for the treatment of hepatitis B provided by the invention etc. are specifically shown in down:
Fang Xie:
Each sample selects quality raw materials, and percentage of admixture is controlled in 0-5%.It is clearing heat and detoxicating by embodiment is controlled by differential diagnosis in tcm,
Phencyclidine, liver-smoothing, qi-regulating, righting of invigorating blood circulation, the combination medicine monarch drug in a prescription have bamboo root seven, polygonum cill, cattle heart seven, the coptis, Prunella vulgaris, tiger
Cane, radix scutellariae, conch seven, folium isatidis, honeysuckle, Fructus Forsythiae, oriental wormwood, dandelion, cockchafer lotus, ground gallbladder, Radix Isatidis, ministerial drug have radix scrophulariae,
Radix rehmanniae recen, Cortex Phellodendri, Chinese mahonia, the root bark of Chinese wolf-berry, cape jasmine, radix paeoniae rubra, radices trichosanthis, field pennycress, radix gentianae, the seed of feather cockscomb, radix ampelopsis, tree peony
Skin, radix bupleuri.Adjutant has Rhizoma Trillii Tschonoskii, and green peel, perfume is logical, Radix Salviae Miltiorrhizae, Asian puccoon, Radix Ophiopogonis, the shell of seaear, rhizoma anemarrhenae, Radix Curcumae, fingered citron, bittersweet, river
Rhizome of chuanxiong.Medicine is set to have ginseng, Radix Astragali, Chinese yam, fructus lycii, Fructus Corni, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae.It is specific as follows:
(1) solution 16 monarchs drug in a prescription in side's embody clearing heat and detoxicating, and wherein bamboo root seven has enriching yin to support lung, promoting blood circulation effect；Polygonum cill
Energy antibacterial antitumor efficacy, has inhibiting effect to staphylococcus aureus, large intestine, green pus, shigella dysenteriae class；The coptis has heat-clearing dry
Wet, purging fire for removing toxin effect, energy antiviral, fungi, effect of lowering blood sugar act on by force, to large intestine and wound staphylococcus and streptococcus
Cold bacillus effect is weak.Prunella vulgaris has clearing heat-fire, and improving eyesight, mass dissipating and swelling eliminating effect, this product decoction is in vitro to shigella dysenteriae, typhoid fever
Bacillus, comma bacillus, Escherichia coli, proteus, staphylococcus and Bacillus tuberculosis have certain inhibiting effect；Polygonum cuspidate
Return liver and gallbladder lung channel, there is removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, removing blood stasis and acesodyne, relieving cough and reducing sputum effect；Radix scutellariae return heart lung gallbladder large intestine channel, has and rushes down
Excess fire, except damp and hot, hemostasis, miscarriage prevention effect, can liver protection, cholagogue, anti-oxidant, have inhibiting effect to hepatitis B；Seven return heart of conch,
Liver, lung channel have clearing heat and detoxicating, swelling and pain relieving, and effect of reducing swelling of relievining asthma, to carbuncle swells scrofula, irregular menstruation is effective.Folium isatidis return heart liver
Stomach meridian, has clearing heat and detoxicating, and blood cooling and ecchymoses removing, antibacterial is antipyretic, protect liver antitumaous effect；Honeysuckle return heart lung stomach meridian, have it is clearing heat and detoxicating,
Anti-inflammatory, qi-restoratives treats the effect of wind, and experiment in vitro shows colored and rattan to various pathogens such as staphylococcus aureus, hemolytic chain
Coccus, Escherichia coli, shigella dysenteriae, comma bacillus, typhoid bacillus, paratyphosum Bacterium are pneumococcus, diplococcus meningitidis, green
Purulence bacillus, tubercle bacillus have certain inhibiting effect；Fructus Forsythiae enters the heart, liver, gallbladder, brothers' shaoyang channel, and energy heat-clearing is detoxified, and dissipating bind disappears
It is swollen, warm is controlled, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes act on, sensitive to typhoid fever, large intestine, dysentery, corynebacterium diphtheriae；
Oriental wormwood returns spleen, stomach, liver, gallbladder channel have clearing heat and promoting diuresis, removing jaundice effect, and pharmaceutical research has cholagogue, and liver function protecting is antipyretic, resist
The effects of inflammation, reducing blood lipid, decompression, coronary dilatation, in vitro test proves, oriental wormwood decoction is to staphylococcus aureus, corynebacterium diphtheriae, anthrax
Bacillus, typhoid bacillus, paratyphoid bacillus A, Pseudomonas aeruginosa, Escherichia coli, bacterium flexneri, Shigella shigae, brain
Film inflammation diplococcus, hay bacillus etc. have different degrees of inhibiting effect；Dandelion enters liver, stomach meridian, there is clearing heat and detoxicating, diuresis dissipating bind
Effect, antibacterial action to Diplococcus pneumopniae, meningococcus, corynebacterium diphtheriae, Pseudomonas aeruginosa, shigella dysenteriae, campylobacter pylori,
Tubercle bacillus, typhoid bacillus etc. and micrococcus catarrhalis also have certain bactericidal effect；Cockchafer lotus return lung stomach meridian has clearing heat and detoxicating, dampness removing
Analgesia, detumescence, benefiting stomach and stopping pain effect；Ground gallbladder returns liver, lung channel, attacks poison, by the stasis of blood, eliminating mass effect.Cure mainly scrofula, malignant sore, breath
Meat, abdominal mass lump in the abdomen；Radix Isatidis return heart, stomach meridian have clearing heat and detoxicating, cool blood, relieving sore-throat effect, antibacterial detumescence, anti-allergic effects, to withered
Grass, large intestine, typhoid fever, shigella dysenteriae have inhibiting effect.
(2) 14 ministerial drugs, which embody phencyclidine, has clearing heat and cooling blood such as radix scrophulariae returns spleen, stomach, kidney channel；Nourishing yin and lessening fire；Removing toxic substances dissipates
Mass-dissipating efficacy；Radix rehmanniae recen return heart, liver, kidney channel, energy clearing heat and cooling blood, yin-nourishing are promoted the production of body fluid, and glutinous rehmannia flooding agent is small to trichophyton mentagrophytes, gypsum sample
The growth of a variety of fungies such as brood cell's tinea bacterium, ulotrichy microsporum and microsporum audouini has inhibiting effect, there is confrontation
Dexamethasone can promote the synthesis of cortex hormone of aadrenaline to the inhibiting effect of Pituitary Adrenalcortical system；Cortex Phellodendri enters
Kidney, bladder meridian, there is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, have the inhibition effect of turning out cloudy to the hepatitis B antigen positive, also
There is inhibiting effect to staphylococcus, pneumococcus, streptococcus, dysentery, cholera, bacillus anthracis；Chinese mahonia energy is clearing heat and detoxicating, disappears
It is swollen not empty, it is sensitive to staphylococcus, large intestine, Pseudomonas aeruginosa, enter lung liver large intestine channel, to sore, hepatitis is effective；The root bark of Chinese wolf-berry returns liver kidney
It is resistant to fungi degradation heat, to typhoid fever, tuberculosis, shigella dysenteriae have inhibiting effect；Cape jasmine enters lung meridian, there is heat-clearing, and purging intense heat is cool
Blood, protect liver cholagogue, decompression detumescence effect, cape jasmine decoction have inhibition to make corynebacterium diphtheriae, staphylococcus aureus, typhoid bacillus
With；Radix paeoniae rubra return liver warp energy clearing heat and cooling blood, removing blood stasis and acesodyne；Radices trichosanthis return lung stomach meridian, has clearing heat-fire, promotes the production of body fluid to quench thirst, detumescence, apocenosis
Effect has antibacterial apocenosis effect；Field pennycress enters stomach, large intestine, Liver Channel, clearing heat and detoxicating, and removing blood stasis and expelling pus, cool blood, Patrinia scaniosaefolia preserved material is in body
Have a slight inhibiting effect to staphylococcus aureus, staphylococcus albus, diphtheroid outside, field pennycress have hepatitis virus resisting,
So that liver cell inflammatory resolution and bile capillaries dredging are acted on, are had promotion liver cell regeneration, prevent degeneration of liver cells, improves liver function
Effect；Radix gentianae returns liver, gallbladder channel, heat-clearing and damp-drying drug, and purging the liver of pathogenic fire is calmed the frightened has inhibition to large intestine, withered grass, green pus, deformation, shigella dysenteriae class
Effect；Seed of feather cockscomb return heart Liver Channel, clearing away the liver-fire effect is strong, and to red eye, swell pain, pruitus, ringworm sore is effective, to Pseudomonas aeruginosa antibacterial
Effect is strong；Radix ampelopsis return heart lung liver and spleen stomach meridian, clearing heat and detoxicating, eliminating stagnation to stop pain, myogenic sore can antimycotic, carcinoma；Cortex moutan enters liver
Kidney channel has clearing heat and cooling blood, promoting blood circulation to remove blood stasis effect, to withered grass, large intestine, typhoid fever, deformation Pseudomonas aeruginosa class, staphylococcus, streptococcus
There is stronger antibacterial action with pneumococcus；Radix bupleuri return liver warp has soothing the liver inducing diaphoresis, purge the green, menstruation regulating effect of bringing down a fever.
(3) adjutant 12 have liver-smoothing, qi-regulating effect, and the tonifying middle-Jiao and Qi of Rhizoma Trillii Tschonoskii energy, myogenic are put on flesh, and returns spleen stomach meridian has decompression to dispel
Wind, relax liver hemostasia effect；Green peel enters liver and gallbladder stomach meridian, there is soothing the liver relieving stagnant Qi, and disperse accumulationization is stagnant, boosting of relievining asthma, Antishock function；Perfume is logical
(Radix Cinnamomi Camphorae) return liver warp, vital energy regualting and blood circulation-promoting, curing rheumatism numbness pain；Radix Salviae Miltiorrhizae enter conscience warp, have promoting blood circulation, it is inducing meastruation to relieve menalgia, clear away heart-fire and remove
Tired, cool blood to disappear carbuncle effect, can hypoglycemic, antibacterial, menstruation regulating；Asian puccoon enters pericardium Liver Channel, there is clearing heat and detoxicating, promoting blood circulation and cooling blood effect, right
Staphylococcus aureus, Bacterium prodigiosum, Escherichia coli have inhibiting effect, effective in cure to chorioadenoma；Radix Ophiopogonis return heart stomach meridian contains ammonia
Base acid, the vitamin antitumor, anti-arrhythmia of energy and myocardial ischemia, there is syngignoscism；The shell of seaear enters liver kidney channel, there is heat-clearing, town
Quiet, hypotensive activity, effect have it is calming the liver, clear liver and improve vision, can antibacterial decompression, protect liver cell, it is green to staphylococcus, large intestine
The inhibitory effect of purulence bacillus is strong；Rhizoma anemarrhenae has nourishing yin and lessening fire moisturizing dryness and lubricating intestine function, to staphylococcus, typhoid bacillus, dysentery, large intestine,
Withered grass, deformation, diphtheria, V.cholerae, Diplococcus pneumopniae, streptococcus, candida albicans have inhibiting effect, enter lung stomach kidney channel；Radix Curcumae function
Effect has promoting blood circulation to stop carbuncle, and promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood, normalizing gallbladder to cure jaundice, and return heart lung Liver Channel can reduce transaminase function；Fingered citron enters liver
Taste warp, there is regulating qi-flowing for eliminating phlegm, preventing or arresting vomiting dissipate-swelling, liver soothing and speen fortifying, stomach function regulating effect；Bittersweet enters liver and gallbladder warp, has clearing heat and promoting diuresis, removing toxic substances disappears
It is swollen, antitumaous effect；Rhizoma Chuanxiong enters conscience gallbladder spleen tri-jiao channel, and brothers faint negative shaoyang channel, has promote breath and open depression, dispels pathogenic wind and remove dampness, promoting blood circulation and stopping pain
Function has inhibiting effect to large intestine, dysentery, deformation, green pus, typhoid bacillus.
(4) medicine is made there are 7, the ginseng return heart lung the spleen channel in side has invigorating qi for relieving desertion, reinforces the spleen to benefit the lung, promoting production of body fluid and inducing sedation of the mind effect, energy
The enzymatic activity for increasing each substance of liver metabolism, enhances the detoxification ability of liver, also there is anti-liver injury；Radix Astragali return lung spleen
Liver kidney channel, there is enhancing body's immunity, and liver protection diuresis resisting stress is depressured antibacterial action；Chinese yam return lung spleen kidney channel controls void hundred
Damage, kidney-nourishing gas, strengthening the spleen and stomach, antidiarrheal dysentery moisten hair, invigorating heart；Fructus lycii returns liver lung kidney channel, there is a nourishing the liver, nourshing kidney, moistening lung, qi-restoratives strengthening the essence,
Heat-clearing improving eyesight function.Fructus Corni, name fructus corni contain 16 kinds of amino acid, and vitamin A C has nourishing liver and kidney QI invigorating stomach invigorating diuresis effect to enter
Liver stomach meridian；When being included into conscience lung channel, enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine, Radix Angelicae Sinensis to external dysentery, typhoid fever, paratyphoid,
Escherichia coli, corynebacterium diphtheriae, comma bacillus and a, B hemolytic streptococcus etc. have antibacterial action, and there are also antithrombotics, improve micro- follow
Ring, liver protection gallbladder kidney, the anti-arrhythmia cordis of feeding lung of enriching blood and artery sclerosis effect；Rhizoma Atractylodis Macrocephalae returns spleen, stomach meridian, strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect,
Hidroschesis, miscarriage prevention, there are also hypoglycemic, anticoagulation, tumour, green blood, synthetic proteins effect, antibacterial actions.
The monarch drug in a prescription group of full side embody it is clearing heat and detoxicating based on drug have polygonum cill, the coptis, polygonum cuspidate, folium isatidis, honeysuckle, Pu
The drugs major part return liver warp such as public English, cockchafer lotus, oriental wormwood, belong to Great Cold class medicine, dose weight, antibacterial action is strong, then be equipped with bamboo root seven,
Conch seven, Fructus Forsythiae, the effect of Radix Isatidis clearing heat and cooling blood, playing i.e. antibacterial has liver protection to promote the production of body fluid effect, and there are also ground gallbladders to enter liver and attack to poison
The stasis of blood, allows the rotten of hepatitis B lesion liver cell, exudation, necrosis, by giving clearing heat and detoxicating cool blood class Chinese medicine, can be obviously improved, allow
The cytoplasm moisture depigmentation concentration that liver cell spherical shape swells, entering after liver there are also clearing heat and cooling blood class Chinese medicine has prevention liver cell interstitial
Reactivity reduces, and reduces cell paraplasm.Ministerial drug embodies based on phencyclidine, it is subject to again on the basis of monarch drug in a prescription is clearing heat and detoxicating
Waste heat is removed, after releasing remaining poison gas, and the liver cell of damage is repaired with phencyclidine drug, to hepatomegaly, quilt
Film anxiety is relieved, and also regenerates new liver cell, this group of medicine is mostly attributed to conscience warp, there is primary and secondary relationship interpromoting relation in five elements effect, than
If field pennycress has hepatitis virus resisting, acts on liver cell inflammatory resolution and bile capillaries dredging, there is promotion liver cell regeneration, prevent
Degeneration of liver cells improves liver function effect.Adjutant embodies liver-smoothing, qi-regulating, and return heart liver stomach meridian mainly has and alleviates the sluggish liver of stomach Qi
Airsetting, blood clotting phenomenon caused by gas catharsis is unsmooth have lobuli hepatis endolymph cell and the sluggish phenomenon of monocyte infiltration bright
It is aobvious to alleviate, also there is transport to gallbladder bolt small in bile capillaries, dredging effect makes medicine body show righting nourshing blood and promoting blood circulation, return heart liver and spleen lung kidney
With righting the five internal organs, is led to and adjust six internal organs, if ginseng, Radix Astragali reinforce vital energy, pulp of dogwood fruit leads to brain mends marrow, and there are also invigorating the spleen to help the white of transporting
Art, the medicines such as Radix Angelicae Sinensis, to hepatitis B invade liver cell after, make stomach upset caused by liver cell dysfunction of the spleen in transportation and transformation, flatus, abdominal distension, easily
Anger etc. is eased.
Drug taste, adverse reaction: because patient is long medication time, can be made into long-acting medicament piece, easy to carry, save, and prevent
Tide, by 112 methods try take, i.e., one week, January, 2 years even served after check follow-up.
Instructions of taking: three times, 15 grams every time, by six months courses for the treatment of, and a course for the treatment of checked Hepatitis B virus to clothes daily,
Understand blood big and small three Yang situation.
Medicinal material requirement: it is required that every medicine is equipped with harmful medicine in growth period less, harvests and is preferred during mature.
The case of the drug for the treatment of hepatitis B provided by the invention is as follows:
One patient, Chen, male make Hepatitis B virus in hospital, Shantou City on April 4th, 2008 age 42 years old when inspection
It checks, hepatitis B surface antigen, e antibody and core antibody are positive (in detection Shantou City, hospital Jinping District second as the result is shown
Detection time: number 3382 detects on April 4th, 2018 in hospital), the results are shown in Table 1, and clinical symptoms are that whole body is aching and limp, liver
Area's expansion is uncomfortable, and dry is bitter, and spirit is poor.It is treated several years in Shantou through multiple hospitals, it is ineffective, on April 21st, 2013
The Chaoyang District commune hospital Gu Rao make Hepatitis B virus reinspection be hepatitis B surface antigen, e antigen and core antigen be the positive, because
It works outside, have to be in ground medical institutions treatment of working, going home on October 9th, 2015, it is right to make hepatitis B two in Pingchang county people's hospital
Half reinspection and liver function test, display hepatitis B surface antigen, e antigen, core antibody are positive, and liver function is respectively worth normal (detection
Pingchang county people's hospital, Sichuan Province, hospital: 151009001155) detection bar code number is that the results are shown in Table 2.
Table 1
| Project name | As a result (PN value) | Term of reference |
| Hepatitis B surface antigen (HBsAg) | 538 | ≦2.1 |
| Hepatitis B surface antibody (HBsAb) | 0.15 | ≦2.1 |
| Hepatitis B virus e antigen (HBeAg) | 0.23 | ≦2.1 |
| Hepatitis B e antibody (HBeAb) | 397 | ≤ 50% |
| Hepatitis B core antibody (HBcAb) | 441 | ≤ 50% |
Table 2
Come at inventor to go to a doctor upon somebody's introduction, receive the treatment of the drug of above-mentioned treatment hepatitis B, amounts to treatment 2 years or more,
Hepatitis B virus, in addition to e antibody positive, original surface antigen, core were rechecked in Pingchang County Zhong De hospital on October 8th, 2016
Antibody switchs to feminine gender, and the results are shown in Table 3.
Table 3
| Project name | As a result | Term of reference | Unit |
| Total bilirubin | 30.77 | 0-10.0 | mmol/L |
| Bilirubin direct | 5.78 | 0.00-6.84 | umol/L |
| Total protein | 56 | 60-85 | g/L |
| Globulin | 13 | 20-30 | g/L |
| Indirect bilirubin | 24.99 | 0.00-7.00 | umol/L |
| Hepatitis B surface antigen (HBsAg) | It is negative | It is negative | |
| Hepatitis B surface antibody (HBsAb) | It is negative | It is negative | |
| Hepatitis B virus e antigen (HBeAg) | It is negative | It is negative | |
| Hepatitis B e antibody (HBeAb) | It is positive | It is negative | |
| Hepatitis B core antibody (HBcAb) | It is negative | It is negative |
Inventor suggests continuing to the drug therapy one-year age for the treatment of hepatitis B provided by the invention, June 11 in 2017
It is feminine gender that day, which is five indexes of hepatitis b in Pingchang Xinhua Hospital reinspection Hepatitis B virus result, and display hepatitis B kills healing, doctor
Institute's review result is as shown in table 4:
Table 4
One patient, Chen, female 24 years old (daughter of above-mentioned patient), also make on July 5th, 2017 in Pingchang Xinhua Hospital
Hepatitis B virus initial survey is hepatitis B surface antigen, e antigen, core antigen are the positives, and liver function value is normal, examining report table 5
It is described, because youth is without any abnormal symptom, abides by father and suggest going to a doctor at inventor, inventor is set to heredity B-type hepatitis,
Or it is given and is treated with top combination medicine.At present also in the treatment.
Table 5
| Project name | As a result | Term of reference | Unit |
| Alkaline phosphatase (ALP) | 36 | 40-150 | U/L |
| Glutamic acid transferase (GGT) | 6 | 7-50 | U/L |
| Hepatitis B surface antigen (HBsAg) | It is positive | It is negative | |
| Hepatitis B surface antibody (HBsAb) | It is negative | It is negative | |
| Hepatitis B virus e antigen (HBeAg) | It is negative | It is negative | |
| Hepatitis B e antibody (HBeAb) | It is positive | It is negative | |
| Hepatitis B core antibody (HBcAb) | It is positive | It is negative |
One patient, Lee, male, 47 years old, because of clinical manifestation: out of strength, sitophobia, nausea, abdominal distension, uncomfortable liver area manifest symptom,
Make Hepatitis B virus in Pingchang county people's hospital on May 29th, 2017 and liver function test is hepatitis B surface antigen e antibody, core
Heart antibody, Anti-HBc Serum -- IgM are that (detection Pingchang county people's hospital, Sichuan Province, hospital: detect bar code number is the positive
170529000044) 6, be the results are shown in Table, liver function test transaminase is high, high (detection Sichuan Province, hospital people from Pingchang County of total bile acid
People hospital: detection bar code number is that 170529000042), the results are shown in Table 7 (abnormal data is only shown in following table):
Table 6
Table 7
| Project name | As a result | Term of reference | Unit |
| Hepatitis B surface antigen (HBsAg) | >165.00 | 0-0.50 | ng/mL |
| Hepatitis B surface antibody (HBsAb) | 0.03 | 0-10.00 | mIU/mL |
| Hepatitis B virus e antigen (HBeAg) | <0.01 | 0-0.40 | PEIU/L |
| Hepatitis B e antibody (HBeAb) | >26.40 | 0-5.00 | PEIU/L |
| Hepatitis B core antibody (HBcAb) | >13.20 | 0-1.50 | PEIU/L |
| Anti- HBc IgM 1:1000 examines (HBc-IgM) | It is positive | It is negative |
Liver function is rechecked in Pingchang county people's hospital because suspecting mistaken diagnosis, and on June 5th, 2017, as a result or exception (is examined
Survey Pingchang county people's hospital, Sichuan Province, hospital: detection bar code number is that 170605000080), the results are shown in Table 8 and (only show in following table
Abnormal data):
Table 8
| Project name | As a result | Term of reference | Unit |
| Total bile acid (TBA) | 29.8 | 0-10.0 | umol/L |
| Glutamic-pyruvic transaminase (ALT) | 125 | 5-40 | U/L |
| Glutamic-oxalacetic transaminease (AsT) | 126 | 0-40 | U/L |
| Γ-glutamic acid transferase (GGT) | 121 | 0-50 | U/L |
| Adenosine deaminase (ADA) | 38 | 0-25 | U/L |
| Phosphorus (P) | 0.78 | 0.8-1.6 | umol/L |
| Potassium (K) | 3.12 | 3.5-6.5 | umol/L |
In June, 2018 goes to a doctor at inventor, judges through inventor, and patient's dysfunction of liver is serious, if not treating, appoints
By the state of an illness continue development may then be converted into liver cancer, patient accepts the suggestion of inventor, using above-mentioned treatment hepatitis B drug into
Row treatment, the symptoms such as patient is out of strength, sitophobia, nausea, abdominal distension, uncomfortable liver area are relieved, at present still in the treatment.
By the practice of inventor's many years, in general, the therapeutic effect of the drug for the treatment of hepatitis B provided by the invention is remote
Be much better than existing Western medicine (such as Lamivudine, uh for card Wei, transfer factor, hepatitis B detoxifying capsule, vitamin E and A Defu it is big
One of rouge etc. is a variety of), therapeutic effect statistics is as follows:
Table 9
The present invention is not limited to above-mentioned optional embodiment, anyone can show that other are each under the inspiration of the present invention
The product of kind form.Above-mentioned specific embodiment should not be understood the limitation of pairs of protection scope of the present invention, protection of the invention
Range should be subject to be defined in claims, and specification can be used for interpreting the claims.
Claims (8)
1. a kind of drug for treating hepatitis B, which is characterized in that be mainly prepared by the raw material of following parts by weight: Rhizoma Trillii Tschonoskii 140-
160 parts, seven 140-160 parts of bamboo root, 140-160 parts of radix scrophulariae, Radix Ophiopogonis 140-160 part, 180-220 parts of fructus lycii, polygonum cill 80-
120 parts, seven 40-60 parts of cattle heart, 140-160 parts of the coptis, 380-420 parts of Radix Rehmanniae, 280-320 parts of the shell of seaear, Cortex Phellodendri 280-320
Part, 280-320 parts of rhizoma anemarrhenae, 180-220 parts of Prunella vulgaris, 280-320 parts of Chinese mahonia, 80-120 parts of Radix Curcumae, polygonum cuspidate 180-220
Part, 180-220 parts of the root bark of Chinese wolf-berry, 280-320 parts of cape jasmine, 280-320 parts of radix paeoniae rubra, 280-320 parts of radix scutellariae, 80-120 parts of fingered citron, sea
Seven 380-420 parts of spiral shell, 80-120 parts of bittersweet, 180-220 parts of folium isatidis, 380-420 parts of honeysuckle, 380-420 parts of Fructus Forsythiae, oriental wormwood
180-220 parts, 140-160 parts of radices trichosanthis, 280-320 parts of dandelion, 80-120 parts of cockchafer lotus, 280-320 parts of pulp of dogwood fruit, gallbladder
80-120 parts, 180-220 parts of Rhizoma Chuanxiong, 280-320 parts of Radix Isatidis, 180-220 parts of field pennycress, 280-320 parts of radix gentianae, the seed of feather cockscomb
280-320 parts, 180-220 parts of radix ampelopsis, 280-320 parts of Radix Angelicae Sinensis, 140-160 parts of Rhizoma Atractylodis Macrocephalae, 280-320 parts of cortex moutan, radix bupleuri 280-
320 parts, 80-120 parts of green peel, fragrant logical 80-120 parts, 180-220 parts of Chinese yam, 280-320 parts of Radix Salviae Miltiorrhizae, 280-320 parts of Asian puccoon, people
380-420 parts and Radix Astragali 380-420 parts of ginseng.
2. the drug for the treatment of hepatitis B according to claim 1, which is characterized in that mainly prepared by the raw material of following parts by weight
It forms: 150 parts of Rhizoma Trillii Tschonoskii, 7 150 parts of bamboo root, 150 parts of radix scrophulariae, 150 parts of Radix Ophiopogonis, 200 parts of fructus lycii, 100 parts of polygonum cill, cattle heart
7 50 parts, 150 parts of the coptis, 400 parts of Radix Rehmanniae, 300 parts of the shell of seaear, 300 parts of Cortex Phellodendri, 300 parts of rhizoma anemarrhenae, 200 parts of Prunella vulgaris, ten big function
300 parts of labor, 100 parts of Radix Curcumae, 200 parts of polygonum cuspidate, 200 parts of the root bark of Chinese wolf-berry, 300 parts of cape jasmine, 300 parts of radix paeoniae rubra, 300 parts of radix scutellariae, fingered citron 100
Part, 7 400 parts of conch, 100 parts of bittersweet, 200 parts of folium isatidis, 400 parts of honeysuckle, 400 parts of Fructus Forsythiae, 200 parts of oriental wormwood, radices trichosanthis
150 parts, 300 parts of dandelion, 100 parts of cockchafer lotus, 300 parts of pulp of dogwood fruit, 100 parts of gallbladder, 200 parts of Rhizoma Chuanxiong, 300 parts of Radix Isatidis, lose
Sauce grass 200 parts, 300 parts of radix gentianae, 300 parts of the seed of feather cockscomb, 200 parts of radix ampelopsis, 300 parts of Radix Angelicae Sinensis, 150 parts of Rhizoma Atractylodis Macrocephalae, 300 parts of cortex moutan,
300 parts of radix bupleuri, 100 parts of green peel, fragrant 100 parts logical, 200 parts of Chinese yam, 300 parts of Radix Salviae Miltiorrhizae, 300 parts of Asian puccoon, 400 parts of ginseng and Radix Astragali
400 parts.
3. the drug for the treatment of hepatitis B according to claim 1 or 2, it is characterised in that: the drug of the treatment treatment hepatitis B
Dosage form be tablet, capsule or pill.
4. a kind of preparation method for the drug for treating hepatitis B, which comprises the steps of: weigh claim 1 according to quantity
Or each raw material of drug described in 2, impurity is removed, each raw material after removal impurity is crushed, is mixed to get the treatment second is arrived
The drug of liver.
5. a kind of application of drug for the treatment of hepatitis B of any of claims 1 or 2 in the drug of preparation treatment hepatopathy.
6. application according to claim 5, it is characterised in that: the hepatopathy is hepatitis B.
7. application according to claim 5, it is characterised in that: the hepatopathy is positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B.
8. application according to claim 5, it is characterised in that: the hepatopathy is hepatitis B "small three positive".
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2018
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106474422A (en) * | 2016-11-07 | 2017-03-08 | 陈中元 | A kind of medicine treating hepatitis B |
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| Title |
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| 江伟: "益气化瘀解毒汤治疗慢性乙型肝炎70例 ", 《实用中医内科杂志》 * |
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Application publication date: 20190503 |