CN109430884A - 小分子肽多种生物营养剂及其制备方法 - Google Patents
小分子肽多种生物营养剂及其制备方法 Download PDFInfo
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Abstract
本发明公开了小分子肽多种生物营养剂及其制备方法，该生物营养剂由小分子肽、橄榄油、维生素、微量元素、竹荪、人参、核桃、乳清粉、牛磺酸、全脂乳粉、氨基酸、干姜、乳酸菌组成；该生物营养剂，营养全面，易于人体吸收；该小分子肽多种生物营养剂的制备方法步骤简单，容易操作。
Description
技术领域
本发明涉及多种生物营养剂，特别是涉及小分子肽多种生物营养剂及其制备方法。
背景技术
近年来，随着科技高速发展，以胶原蛋白肽、海洋低聚肽、玉米低聚肽、大豆蛋白肽等为代表的生物小分子多肽产品以其卓越的生物营养保健功能逐渐被广大群众认可，被广泛应用于医药、保健、食品、化妆品领域；近年来的研究发现，小分子肽在人体内不需消化，即可直接吸收，利用度较高，现有市场上的营养剂、营养食品含有小分子肽的组方单一，例如豌豆小分子肽、蓝莓小分子肽、鹿参小分子肽、牡蛎蛋白小分子肽，营养成分较为单一，综合营养保健功能不能充分发挥，不易于人体吸收。
发明内容
为了解决上述技术问题，本发明提供了一种小分子肽多种生物营养剂，该生物营养剂，营养全面，易于人体吸收；该小分子肽多种生物营养剂的制备方法步骤简单，容易操作。
本发明的目的是通过下述技术方案实现的：
小分子肽多种生物营养剂，由以下质量份数的各组份组成：小分子肽30-55份、橄榄油10-20份、维生素2-10份、微量元素1-5份、竹荪1-4份、人参3-9份、核桃5-15份、乳清粉4-8份、牛磺酸1-2份、全脂乳粉1-5份、氨基酸2-6份、干姜1-6份、乳酸菌5-10份。
进一步的，所述小分子肽为分子量小于1000道尔顿的小分子胶原蛋白肽或 酪蛋白磷酸肽。
进一步的，所述维生素由以下质量份数的各组份组成：维生素A 1-5份、维生素B1-4份、维生素C 2-8份、维生素D 1-5份、维生素E 1-4份。
进一步的，所述微量元素由以下质量份数的各组份组成：铁1-2份、铜1-2份、锌1份、锰1份、铬1-2份、硒1.5份。
小分子肽多种生物营养剂的制备方法，制备步骤如下：
（1）将竹荪、人参、核桃、干姜混合，加入6-12倍的去离子水，进行沸水冷凝回流浸提，沸水冷凝回流浸提次数为2-3次，煎煮时间为2－4 小时，水体温度控制在100－120℃，将每次的沸水冷凝回流浸提法制得滤液合并，制得过滤液A；
（2）将配方量的小分子肽、橄榄油、维生素、微量元素、乳清粉、牛磺酸、全脂乳粉、氨基酸混合均匀，加热至45-75℃，保温持续搅拌20-50分钟，制得过滤液B；
（3）将制得的过滤液A和过滤液B混合均匀，再加入乳酸菌，于20℃的厌氧环境中，培育40h，制得小分子肽多种生物营养剂。
有益效果
本发明由小分子肽、橄榄油、维生素、微量元素、乳酸菌等组成，其中小分子肽易于人体吸收；而橄榄油富含丰富的单不饱和脂肪酸—油酸，还有维生素A、维生素B、维生素D、维生素E、维生素K及抗氧化物等。橄榄油被认为是迄今所发现的油脂中最适合人体营养的油，能调整人体血浆中高、低密度脂蛋白胆固醇的比例，能增加人体内的高密度脂蛋白HDL(好胆固醇)的水平和降低低密度脂蛋白LDL(坏胆固醇)水平，从而能防止人体内胆同醇过量；该生物营养剂还辅以维生素、微量元素、乳清粉、牛磺酸、氨基酸，其营养全面补充，再加以乳酸菌调理更好的激发各组分的作用，该营养剂制备方法简单易行。
具体实施例
下面通过具体的实施方案叙述本发明，除非特别说明，本发明中所用的技术手段均为本领域技术人员所公知的方法。另外，实施方案应理解为说明性的，而非限制本发明的范围，本发明的实质和范围仅由权利要求书所 限定。对于本领域技术人员而言，在不背离本发明实质和范围的前提下，对这些实施方案中的物料成分和用量进行的各种改变或改动也属于本发明的保护范围。
实施例1
小分子肽多种生物营养剂，由以下质量份数的各组份组成：小分子肽30份、橄榄油10份、维生素2份、微量元素1份、竹荪1份、人参3份、核桃5份、乳清粉4份、牛磺酸1份、全脂乳粉1份、氨基酸2份、干姜1份、乳酸菌5份；所述小分子肽为分子量小于1000道尔顿的小分子胶原蛋白肽；所述维生素由以下质量份数的各组份组成：维生素A 1份、维生素B 1份、维生素C2份、维生素D 1份、维生素E 1份；所述微量元素由以下质量份数的各组份组成：铁1份、铜1份、锌1份、锰1份、铬1份、硒1.5份。
小分子肽多种生物营养剂的制备方法，制备步骤如下：
（1）将竹荪、人参、核桃、干姜混合，加入6倍的去离子水，进行沸水冷凝回流浸提，沸水冷凝回流浸提次数为2次，煎煮时间为2小时，水体温度控制在100℃，将每次的沸水冷凝回流浸提法制得滤液合并，制得过滤液A；
（2）将配方量的小分子肽、橄榄油、维生素、微量元素、乳清粉、牛磺酸、全脂乳粉、氨基酸混合均匀，加热至45℃，保温持续搅拌20分钟，制得过滤液B；
（3）将制得的过滤液A和过滤液B混合均匀，再加入乳酸菌，于20℃的厌氧环境中，培育40h，制得小分子肽多种生物营养剂。
实施例2
小分子肽多种生物营养剂，由以下质量份数的各组份组成：小分子肽55份、橄榄油20份、维生素10份、微量元素5份、竹荪4份、人参9份、核桃15份、乳清粉8份、牛磺酸2份、全脂乳粉5份、氨基酸6份、干姜6份、乳酸菌10份；所述小分子肽为分子量小于1000道尔顿的酪蛋白磷酸肽；所述维生素由以下质量份数的各组份组成：维生素A 5份、维生素B 4份、维生素C 8份、维生素D 5份、维生素E 4份；所述微量元素由以下质量份数的各组份组成：铁2份、铜2份、锌1份、锰1份、铬2份、硒1.5份。
小分子肽多种生物营养剂的制备方法，制备步骤如下：
（1）将竹荪、人参、核桃、干姜混合，加入12倍的去离子水，进行沸水冷凝回流浸提，沸水冷凝回流浸提次数为3次，煎煮时间为4 小时，水体温度控制在120℃，将每次的沸水冷凝回流浸提法制得滤液合并，制得过滤液A；
（2）将配方量的小分子肽、橄榄油、维生素、微量元素、乳清粉、牛磺酸、全脂乳粉、氨基酸混合均匀，加热至75℃，保温持续搅拌50分钟，制得过滤液B；
（3）将制得的过滤液A和过滤液B混合均匀，再加入乳酸菌，于20℃的厌氧环境中，培育40h，制得小分子肽多种生物营养剂。
实施例3
小分子肽多种生物营养剂，由以下质量份数的各组份组成：小分子肽45份、橄榄油15份、维生素6份、微量元素3份、竹荪2.5份、人参4份、核桃10份、乳清粉6份、牛磺酸1.5份、全脂乳粉3份、氨基酸4份、干姜3份、乳酸菌8份；所述小分子肽为分子量小于1000道尔顿的小分子胶原蛋白肽；所述维生素由以下质量份数的各组份组成：维生素A3份、维生素B 3份、维生素C 5份、维生素D 3份、维生素E 3份；所述微量元素由以下质量份数的各组份组成：铁1.5份、铜2份、锌1份、锰1份、铬2份、硒1.5份。
小分子肽多种生物营养剂的制备方法，制备步骤如下：
（1）将竹荪、人参、核桃、干姜混合，加入10倍的去离子水，进行沸水冷凝回流浸提，沸水冷凝回流浸提次数为3次，煎煮时间为2.5 小时，水体温度控制在120℃，将每次的沸水冷凝回流浸提法制得滤液合并，制得过滤液A；
（2）将配方量的小分子肽、橄榄油、维生素、微量元素、乳清粉、牛磺酸、全脂乳粉、氨基酸混合均匀，加热至60℃，保温持续搅拌40分钟，制得过滤液B；
（3）将制得的过滤液A和过滤液B混合均匀，再加入乳酸菌，于20℃的厌氧环境中，培育40h，制得小分子肽多种生物营养剂。
实施例4
小分子肽多种生物营养剂，由以下质量份数的各组份组成：小分子肽45份、橄榄油15份、维生素10份、微量元素1份、竹荪4份、人参3份、核桃15份、乳清粉4份、牛磺酸2份、全脂乳粉4份、氨基酸6份、干姜6份、乳酸菌5份、葡萄子提取物9份、生育酚8份；所述小分子肽为分子量小于1000道尔顿的酪蛋白磷酸肽；所述维生素由以下质量份数的各组份组成：维生素A1份、维生素B 1份、维生素C 2份、维生素D 1份、维生素E 1份；所述微量元素由以下质量份数的各组份组成：铁2份、铜2份、锌1份、锰1份、铬2份、硒1.5份。
小分子肽多种生物营养剂的制备方法，制备步骤如下：
（1）将竹荪、人参、核桃、干姜混合，加入11倍的去离子水，进行沸水冷凝回流浸提，沸水冷凝回流浸提次数为3次，煎煮时间为3 小时，水体温度控制在100℃，将每次的沸水冷凝回流浸提法制得滤液合并，制得过滤液A；
（2）将配方量的小分子肽、橄榄油、维生素、微量元素、乳清粉、牛磺酸、全脂乳粉、氨基酸、葡萄子提取物、生育酚混合均匀，加热至60℃，保温持续搅拌40分钟，制得过滤液B；
（3）将制得的过滤液A和过滤液B混合均匀，再加入乳酸菌，于20℃的厌氧环境中，培育40h，制得小分子肽多种生物营养剂。
实验方法
下面通过具体试验，进一步说明本发明产品对有效改进肠内微生物菌落状态，同时能有效增强肠胃动力的影响，以证明本发明的易于吸收，营养全面的优异性。
试验动物为雌性小鼠，体重18-22g。对照组每日早上8-9点之间灌喂10ml蒸馏水，对照组1灌喂10mg/L的本发明实施例1的产品10ml；对照组2灌喂10mg/L的本发明实施例2的产品10ml；对照组3灌喂10mg/L的本发明实施例3的产品10m；对照组4灌喂10mg/L的本发明实施例4的产品10ml，持续15天。
肠道菌群的计数
无菌采取小鼠粪便，放入已灭菌的装有3ml稀释液的试管中，称重，振荡混匀。采取10倍系列稀释至10-8或10-9，选择合适的稀释度分别接种在培养基上。培养48小时后，以菌落形态，革兰氏染色镜检计数菌落，计算出每克湿便中的菌数，取对数后进行统计处理。
结果与分析 小鼠肠道菌群分析如下表：
从上表，可以确定的是，肠道有益菌群的增加将有利于身体免疫能力的提升，促 进肠道吸收能力。
该生物营养剂，营养全面，易于人体吸收，口感好；制备方法步骤简单，容易操作。
以上所述仅为本发明的较佳实施例，并不用以限制本发明，凡在本发明的精神和原则之内所作的任何修改、同等替换和改进等，均应落在本发明的保护范围之内。
Claims (5)
1.小分子肽多种生物营养剂，其特征在于，由以下质量份数的各组份组成：小分子肽30-55份、橄榄油10-20份、维生素2-10份、微量元素1-5份、竹荪1-4份、人参3-9份、核桃5-15份、乳清粉4-8份、牛磺酸1-2份、全脂乳粉1-5份、氨基酸2-6份、干姜1-6份、乳酸菌5-10份。
2.根据权利要求1所述的小分子肽多种生物营养剂，其特征在于，所述小分子肽为分子量小于1000道尔顿的小分子胶原蛋白肽或 酪蛋白磷酸肽。
3.根据权利要求1所述的小分子肽多种生物营养剂，其特征在于，所述维生素由以下质量份数的各组份组成：维生素A 1-5份、维生素B 1-4份、维生素C 2-8份、维生素D 1-5份、维生素E 1-4份。
4.根据权利要求1所述的小分子肽多种生物营养剂，其特征在于，所述微量元素由以下质量份数的各组份组成：铁1-2份、铜1-2份、锌1份、锰1份、铬1-2份、硒1.5份。
5.根据权利要求1所述的小分子肽多种生物营养剂的制备方法，其特征在于，制备步骤如下：（1）将竹荪、人参、核桃、干姜混合，加入6-12倍的去离子水，进行沸水冷凝回流浸提，沸水冷凝回流浸提次数为2-3次，煎煮时间为2－4 小时，水体温度控制在100－120℃，将每次的沸水冷凝回流浸提法制得滤液合并，制得过滤液A；（2）将配方量的小分子肽、橄榄油、维生素、微量元素、乳清粉、牛磺酸、全脂乳粉、氨基酸混合均匀，加热至45-75℃，保温持续搅拌20-50分钟，制得过滤液B；（3）将制得的过滤液A和过滤液B混合均匀，再加入乳酸菌，于20℃的厌氧环境中，培育40h，制得小分子肽多种生物营养剂。
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