CN109420156A - A kind of drug of thrombolysis lipid-lowering row bolt - Google Patents
A kind of drug of thrombolysis lipid-lowering row bolt Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K38/011—Hydrolysed proteins; Derivatives thereof from plants
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Abstract
The invention discloses a kind of drugs of thrombolysis lipid-lowering row's bolt, and drug is formulated by the herbal raw material of following weight: 1-6 parts of ginseng, 1-8 parts of hawthorn, 1-9 parts of Chinese yam, seven 2-6 parts of mountain, 2-7 parts of donkey-hide gelatin, 1-7 parts of linseed oil, 5-11 parts of soybean oligopeptide, 8-15 parts of maize oligopeptide.Choice of drug natural plant of the invention is raw material, and each component meets pharmaceutical control and administration law regulation, treats cardiovascular and cerebrovascular diseases using the comprehensive function of each taste medicine, and no chemicals is non-toxic to humans, without side-effects, securely and reliably.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, more specifically to a kind of drug of thrombolysis lipid-lowering row's bolt.
Background technique
In recent years, with the change of China's economic development and dietary structure, high-fat, high protein intake increase is led
Three high disease incidences are caused to be on the rise, disease incidence is high in crowd, and healing difficulty is big, has seriously affected the life of patient
Quality.
So-called three height refers to hypertension, hyperlipidemia and hyperglycemia, mostly by people undesirable life style and Fei Ke for a long time
Eating habit causes, such as overfeeding is greasy, smoking and drinking, overworked.On the surface, three height have respectively different hairs
Anttdisease Mechanism and pathological change.From essential analysis, this 4 kinds of diseases of diabetes, hypertension, coronary heart disease and hyperlipidemia are actually one
Matter, with one of disease, the risk for suffering from other diseases just will increase many times.
Hypertension will lead to cerebrovascular ischemia or denaturation, so as to cause cerebral hemorrhage or cerebral thrombosis, that is, usually
Described apoplexy.Long-term continuous hypertension will lead to nephridial tissue ischemic, cause renal failure.Make eye ground parteriole that convulsion occur
Contraction, hardening, blood pressure sharply increase and also result in retinal hemorrhage etc..Therefore, it is more to damage the heart, brain, kidney, eye etc. for long-term hypertension
A organ.Hyperlipidemia is the main factor of heart coronary artery atherosclerotic heart disease, can jeopardize each organ, hyperlipidemia
Early stage and it is slight when almost without any feeling, the pathogenic of it is a slowly process, be frequently in it is between twenty and fifty very
It is begun in period to child.Because of the feeling without significant discomfort, tend not to find in time, but long-term do not treat can cause the heart
The diseases such as colic pain, myocardial infarction, sudden death, headstroke, while hyperlipidemia also can be with the phases interaction such as fatty liver, hypertension, diabetes
With promoting the progressive deterioration of the state of an illness, consequence is very serious.Hyperglycemia can seriously affect big blood vessel, tiny blood vessels, the nerve of human body
Deng leading to cardiovascular and cerebrovascular disease such as hypertension, apoplexy, coronary heart disease, cause renal failure, cataract etc., can also cause some nerveous systems
The symptom of system, such as numb in every limb, shouting pain, severe pain, serious person can also cause diabetic foot, lead to foot infection, gangrene.Three is high
Can be with individualism, also tight association from each other.
Treating the rough drug of the disease both at home and abroad is mainly Western medicine, but above-mentioned drug all has serious adverse reaction, for a long time
Using or the excessive other histoorgans of human body that will lead to of dosage be abnormal.Treatment of the Chinese medicine to such illness, though weight sample is simultaneous
It controls, but also mostly anxious for success, lacks longer term systematic therapeutic scheme, and according to the principle of diagnosis and treatment based on an overall analysis of the illness and the patient's condition, prescription
Without end, I is unequal to, and its is numerous for adjustment, finally often ends up with nothing definite, cured person is very few.There are many synthesis prescription occurred in recent years, but its
Curative effect is irregular to be differed, and general effect is not satisfactory.
Summary of the invention
In view of the deficiencies of the prior art, the present invention intends to provide a kind of drug of thrombolysis lipid-lowering row bolt,
Obvious to cardiovascular and cerebrovascular curative effect, selection natural plant is raw material, and each component meets pharmaceutical control and administration law regulation, utilizes the synthesis of each taste medicine
URIN Treatment cardiovascular and cerebrovascular diseases keep its performance heart Maitong smooth, the effect of normal circulation of qi and blood, and without chemicals, nontoxic to the human body
It is harmless, it is without side-effects, it securely and reliably, while efficiently being extracted after present invention crushing, effective component is scattered and disappeared less, and curative effect is high, and price is low
It is honest and clean, convenient to take, the appearance of no any discomfort symptom.
To achieve the above object, the present invention provides the following technical scheme that
A kind of drug of thrombolysis lipid-lowering row bolt, it is characterised in that: drug is by the herbal raw material of following weight
It is formulated: 1-6 parts of ginseng, 1-8 parts of hawthorn, 1-9 parts of Chinese yam, seven 2-6 parts of mountain, 2-7 parts of donkey-hide gelatin, 1-7 parts of linseed oil, greatly
5-11 parts of beans oligopeptide, 8-15 parts of maize oligopeptide.
As a kind of technical solution of optimization, drug is formulated by the herbal raw material of following weight: people
1-5 parts of ginseng, 1-5 parts of hawthorn, 2-9 parts of Chinese yam, seven 2-4 parts of mountain, 2-6 parts of donkey-hide gelatin, 2-6 parts of linseed oil, soybean oligopeptide 6-11
Part, 10-15 parts of maize oligopeptide.
As a kind of technical solution of optimization, the drug be by following weight herbal raw material prepare and
At: 2 parts of ginseng, 3 parts of hawthorn, 3 parts of Chinese yam, 73 parts of mountain, 2 parts of donkey-hide gelatin, 4 parts of linseed oil, 8 parts of soybean oligopeptide, corn is low
10 parts of poly- peptide.
As a kind of technical solution of optimization, the drug be by following weight herbal raw material prepare and
At: 3 parts of ginseng, 3 parts of hawthorn, 2 parts of Chinese yam, 73 parts of mountain, 3 parts of donkey-hide gelatin, 2 parts of linseed oil, 8 parts of soybean oligopeptide, corn is low
10 parts of poly- peptide.
As a kind of technical solution of optimization, the drug be by following weight herbal raw material prepare and
At: 3 parts of ginseng, 4 parts of hawthorn, 4 parts of Chinese yam, 75 parts of mountain, 2 parts of donkey-hide gelatin, 4 parts of linseed oil, 8 parts of soybean oligopeptide, corn is low
10 parts of poly- peptide.
The preparation method of the Chinese herbal medicine is: each component herbal raw material being picked up net impurity elimination, cleans and dries, and press
The weight is crushed, and crosses 150-240 mesh and powder is made, drug of the invention is made in uniform mixing.It takes
It is to take orally once a day with method, 30 grams every time, warm water delivery service.
The function difference of this drug each component is as follows:
Ginseng: reinforcing vital energy, prevent prolapse and engender liquid, calms the nerves.It is deficient to control internal lesion caused by overexertion, deficiency of food, burnout, regurgitation and emesis, stool slide-let out,
Cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, amnesia, dizziness and headache, sun-impotence, frequent micturition are quenched one's thirst, woman uterine bleeding, infantile chronic fright, Ji Jiuxu
It is not multiple, the card of all qi-blood-body fluid deficiencies.
Hawthorn: having effects that antibacterial, aid digestion, reducing blood lipid, antiatherosclerosis, the effect to cardiovascular system.
Chinese yam: it is sweet in flavor, mild-natured, enter lung, spleen, kidney channel；It is not dry oiliness.With strengthening the spleen and tonifying the lung, beneficial stomach kidney tonifying, reinforce the kidney beneficial essence,
Hearing-improing and eyesight improving helps the five internal organs, strengthening the bones and muscles, long will to calm the nerves, the effect of promoting longevity.Cure mainly weakness of the spleen and the stomach, lassitude, appetite not
Vibration, chronic diarrhea and dysentery, Lung Qi deficiency is dry, phlegm asthma cough, kidney qi loss, soreness and weakness of waist and knees, lower limb impotence is weak, frequent micturition of quenching one's thirst, premature ejaculation of passing out semen, band
The illnesss such as the red swollen, obesity of lower gonorrhoea, skin
Mountain seven has effects that " ripe benefit is beaten in life ".Raw sangqi ginseng takes raw sangqi ginseng for disease and healthcare function in terms of blood,
Can activating microcirculation and removing stasis medicinal, swelling and pain relieving, it is effective that ginseng controls bruise internal lesion caused by overexertion, cure mainly hemoptysis, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest
Ventral spine pain falls servant's swelling and pain.Compendium of Material Medica cloud: " pseudo-ginseng hemostatic dissipates blood, analgesic therapy." " jade seizes medicine solution " cloud: " Radix Notoginseng and battalion's hemostasis,
Promote blood circulation the row stasis of blood, row hemostasis and hold back new blood.Take ripe Radix Notoginseng energy blood nourishing body building.Radix Notoginseng contains tetracyclic triterpene etc. as ginseng takes a tonic or nourishing food to build up one's health into
Part, and it is also higher than people's content containing ginseng, ketone compounds contained by Radix Notoginseng can promote blood circulation, coronary artery dilator, reduce
Heart oxygen demand mitigates myocardium work load
The good medicine of Colla Corii Asini nourishing blood hemostasis, nourishing Yin and moistening dryness, clinical application is in blood deficiency chlorosis, dizziness palpitaition, impotence weakness, vexed
Insomnia, endogenous deficient wind, xeropulmonary cough, phthisical cough hemoptysis, haematemesis, uterine bleeding of having blood in stool etc. have significant curative effect.Donkey-hide gelatin has green blood
Effect, can be used for blood loss anaemia, iron deficiency anaemia, aplastic anemia and old and frail, children, women nourishings, and to children,
Teen-age growth and development has improvement result
Linseed oil has effects that 11 kinds: 1, reducing blood lipid, blood pressure lowering prevent cardiovascular and cerebrovascular disease；2, gout and wind are adjusted
Wet rheumatoid；3, anticancer function；4, inhibit thrombotic diseases, prevent myocardial infarction and cerebral infarction；5, highly protective eyesight；6, high
Degree increases intelligence；7, inhibit allergic reaction；8, anti-inflammatory efficacy；9, inhibit the generation and transfer of cancer；10, inhibit aging；11,
Insulin secretion accelerating extends hypoglycemic effect.
Soybean oligopeptide contains Several Active Peptides, has a variety of physiological activity, including anti-oxidant, blood pressure lowering, reduction
Cholesterol, reducing blood lipid, antifatigue, enhancing is immune etc..
Maize oligopeptide is sized mixing, protease hydrolyzed, separation, filtering, the works such as spray drying using corn protein powder as raw material
What skill produced.It is a kind of new resources product, can be applied to blood pressure lowering, Soboring-up liver-protecting, enhances immune and enhancing locomitivity.
By adopting the above-described technical solution, compared with prior art, the beneficial effects of the present invention are:
1, choice of drug natural plant of the invention is raw material, and each component meets pharmaceutical control and administration law regulation, utilizes each taste medicine
Cardiovascular and cerebrovascular diseases are treated in comprehensive function, and no chemicals is non-toxic to humans, without side-effects, securely and reliably.
2, drug of the invention efficiently extracts after crushing, and effective component is scattered and disappeared less, and curative effect is high, cheap, convenient to take,
Without any discomfort disease.
3, drug of the invention is obvious to cardiovascular and cerebrovascular curative effect, may replace the drug of other treatment cardiovascular and cerebrovascular.
Specific embodiment
The present invention is the pathogenetic understanding and its principle of reatment according to traditional Chinese medicine to thrombus, with reference to modern medicine
Reason research, is screened out from it tonifying qi and reducing fat, prevent prolapse of promoting blood circulation, thrombolysis of enriching blood arranges the natural Chinese medicinal herb of bolt, by traditional Chinese medical theory group
Side keeps its performance heart Maitong smooth, the effect of normal circulation of qi and blood.
The present invention is the drug that a kind of thrombolysis lipid-lowering arranges bolt, and drug is prepared by the herbal raw material of following weight
It forms: 1-6 parts of ginseng, 1-8 parts of hawthorn, 1-9 parts of Chinese yam, seven 2-6 parts of mountain, 2-7 parts of donkey-hide gelatin, 1-7 parts of linseed oil, soy oligosaccharides
5-11 parts of peptide, 8-15 parts of maize oligopeptide.
Embodiment 1
Case treatment be with thrombolysis as the main purpose, the drug of a kind of thrombolysis lipid-lowering row's bolt, by following weight
Herbal raw material is formulated: 2 parts of ginseng, 3 parts of hawthorn, 3 parts of Chinese yam, 73 parts of mountain, 2 parts of donkey-hide gelatin, 4 parts of linseed oil, soybean is low
8 parts of poly- peptide, 10 parts of maize oligopeptide.
The preparation method of drug is: each component herbal raw material being picked up net impurity elimination, cleans and dries, and presses the weight
Part proportion is crushed, and crosses 150-240 mesh and powder is made, drug of the invention is made in uniform mixing.Its instructions of taking is
It takes orally once a day, 30 grams every time, warm water delivery service.
Embodiment 2
Case treatment be with lipid-loweringing as the main purpose, the drug of a kind of thrombolysis lipid-lowering row's bolt, by following weight
Herbal raw material is formulated: 3 parts of ginseng, 3 parts of hawthorn, 2 parts of Chinese yam, 73 parts of mountain, 3 parts of donkey-hide gelatin, 2 parts of linseed oil, soybean is low
8 parts of poly- peptide, 10 parts of maize oligopeptide.
The preparation method of drug is: each component herbal raw material being picked up net impurity elimination, cleans and dries, and presses the weight
Part proportion is crushed, and crosses 150-240 mesh and powder is made, drug of the invention is made in uniform mixing.Its instructions of taking is
It takes orally once a day, 30 grams every time, warm water delivery service.
Embodiment 3
Case treatment be with lipid-loweringing as the main purpose, the drug of a kind of thrombolysis lipid-lowering row's bolt, by following weight
Herbal raw material is formulated: 3 parts of ginseng, 4 parts of hawthorn, 4 parts of Chinese yam, 75 parts of mountain, 2 parts of donkey-hide gelatin, 4 parts of linseed oil, soybean is low
8 parts of poly- peptide, 10 parts of maize oligopeptide.
The preparation method of drug is: each component herbal raw material being picked up net impurity elimination, cleans and dries, and presses the weight
Part proportion is crushed, and crosses 150-240 mesh and powder is made, drug of the invention is made in uniform mixing.Its instructions of taking is
It takes orally once a day, 30 grams every time, warm water delivery service.
In summary patient, according to the principle voluntarily selected, takes medium-height grass of the present invention by taking 500 nearest patients as an example
Medicine curer 500, significant effect person 239, effective person 261, total effective rate is up to 100%, and follow-up in cured person
Whether there is or not recidivists.
Following table is the statistical form of 500 patients:
| Group | Case load | Significant effect person | Effective person | Nonresponder | Total effective rate |
| Voluntary group | 500 | 239 | 261 | 0 | 100 |
| Control group | 100 | 0 | 78 | 22 | 78.0 |
| T | 2.50 | 5.68 | 2.30 | 3.89 | |
| P | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 |
The efficacy assessment standard of above-mentioned treatment is: significant effect: blood lipid laboratory indexes are normal, and embolism all disappears, function
It is movable all normal.Effective: pain symptom is eliminated, and function of joint returns to normal, and can participate in slight work or manual labor；
Invalid: after using Chinese herbal medicine of the present invention, symptom and sign is not improved.
Protection scope of the present invention is not limited merely to above-described embodiment, and all technical solutions belonged under thinking of the present invention are equal
It belongs to the scope of protection of the present invention.It should be pointed out that for those skilled in the art, not departing from the present invention
Several improvements and modifications under the premise of principle, these modifications and embellishments should also be considered as the scope of protection of the present invention.
Claims (5)
1. a kind of drug of thrombolysis lipid-lowering row bolt, it is characterised in that: drug is matched by the herbal raw material of following weight
Make: 1-6 parts of ginseng, 1-8 parts of hawthorn, 1-9 parts of Chinese yam, seven 2-6 parts of mountain, 2-7 parts of donkey-hide gelatin, 1-7 parts of linseed oil, soybean is low
Poly- peptide 5-11 parts, 8-15 parts of maize oligopeptide.
2. a kind of drug of thrombolysis lipid-lowering row bolt according to claim 1, it is characterised in that: drug is by following parts by weight
The herbal raw material of proportion is formulated: 1-5 parts of ginseng, 1-5 parts of hawthorn, 2-9 parts of Chinese yam, seven 2-4 parts of mountain is 2-6 parts of donkey-hide gelatin, sub-
2-6 parts of flaxseed oil, 6-11 parts of soybean oligopeptide, 10-15 parts of maize oligopeptide.
3. a kind of drug of thrombolysis lipid-lowering row bolt according to claim 1 or 2, it is characterised in that: the drug be by
The herbal raw material of following weight is formulated: 2 parts of ginseng, 3 parts of hawthorn, 3 parts of Chinese yam, 73 parts of mountain is 2 parts of donkey-hide gelatin, sub-
4 parts of flaxseed oil, 8 parts of soybean oligopeptide, 10 parts of maize oligopeptide.
4. a kind of drug of thrombolysis lipid-lowering row bolt described in claims 1 or 2, it is characterised in that: the drug is by following
The herbal raw material of weight is formulated: 3 parts of ginseng, 3 parts of hawthorn, and 2 parts of Chinese yam, 73 parts of mountain, 3 parts of donkey-hide gelatin, linseed
2 parts, 8 parts of soybean oligopeptide, 10 parts of maize oligopeptide of oil.
5. a kind of drug of thrombolysis lipid-lowering row bolt described in claims 1 or 2, it is characterised in that: the drug is by following
The herbal raw material of weight is formulated: 3 parts of ginseng, 4 parts of hawthorn, and 4 parts of Chinese yam, 75 parts of mountain, 2 parts of donkey-hide gelatin, linseed
4 parts, 8 parts of soybean oligopeptide, 10 parts of maize oligopeptide of oil.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710746364.8A CN109420156A (en) | 2017-08-26 | 2017-08-26 | A kind of drug of thrombolysis lipid-lowering row bolt |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710746364.8A CN109420156A (en) | 2017-08-26 | 2017-08-26 | A kind of drug of thrombolysis lipid-lowering row bolt |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1279073A (en) * | 2000-04-17 | 2001-01-10 | 李熙德 | Antisenility Chinese medicine |
| CN102940801A (en) * | 2012-11-08 | 2013-02-27 | 西安福安创意咨询有限责任公司 | Traditional Chinese medicine composition for treating hypertension |
| CN103417753A (en) * | 2013-08-06 | 2013-12-04 | 南京弘典医药科技有限公司 | Vegetable oil composition with heart and cerebral vessel protecting function, as well as preparation method and application of vegetable oil composition |
| CN106938048A (en) * | 2017-04-11 | 2017-07-11 | 王敬顺 | A kind of Chinese medicine preparation for treating cardiovascular and cerebrovascular disease |
-
2017
- 2017-08-26 CN CN201710746364.8A patent/CN109420156A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1279073A (en) * | 2000-04-17 | 2001-01-10 | 李熙德 | Antisenility Chinese medicine |
| CN102940801A (en) * | 2012-11-08 | 2013-02-27 | 西安福安创意咨询有限责任公司 | Traditional Chinese medicine composition for treating hypertension |
| CN103417753A (en) * | 2013-08-06 | 2013-12-04 | 南京弘典医药科技有限公司 | Vegetable oil composition with heart and cerebral vessel protecting function, as well as preparation method and application of vegetable oil composition |
| CN106938048A (en) * | 2017-04-11 | 2017-07-11 | 王敬顺 | A kind of Chinese medicine preparation for treating cardiovascular and cerebrovascular disease |
Non-Patent Citations (1)
| Title |
|---|
| 马文领等: "《心脑血管疾病预警与干预CWPAS健康管理系统概论》", 31 January 2014, 军事医学科学出版社 * |
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Application publication date: 20190305 |