CN109394565B - Moisturizing and repairing composition and application thereof - Google Patents

Abstract

The invention discloses a moisturizing repair composition and application thereof, wherein the moisturizing repair composition comprises the following components: artocarpus heterophyllus stem cell extract, hyaluronic acid and ceramide. The invention creatively applies the millettia stem cell extract to cosmetics, and prepares the moisturizing repair composition by compounding the millettia stem cell extract, hyaluronic acid and ceramide. Experiments prove that the moisturizing and repairing composition has the effects of moisturizing, locking water and preserving moisture for a long time, is fresh, cool, not sticky, high in safety, free of stimulation and quick to absorb, and is suitable for various skins. The extract of the Artocarpus heterophyllus stem cells, the hyaluronic acid and the ceramide can interact with each other to generate a synergistic effect, so that the moisturizing repair composition has a better moisturizing repair effect.

Description

Moisturizing and repairing composition and application thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a moisturizing and repairing composition and application thereof.

Background

Nowadays, with the aggravation of environmental pollution, the increase of working pressure of people, irregular work and rest and other factors, skin disorders such as dry skin and pruritus are puzzling people increasingly, and moisturizing cosmetics are receiving more and more attention of consumers. Moisturizing cosmetics mainly achieve a moisturizing effect through a moisturizing agent, and the moisturizing agent is an important part of daily skin care products of people and is used for keeping moisture of stratum corneum, maintaining skin elasticity and promoting repair of skin barrier function.

Although most of the traditional cosmetic moisturizing agents have good moisturizing effect and stability, the traditional cosmetic moisturizing agents generally have sticky feeling, the skin feeling after use is not fresh enough, and the moisturizing time is not long enough. Even some moisturizers can absorb moisture in the inner layer of the skin under certain conditions, so that the skin is drier; or the closure is too strong, which causes unsmooth skin excretion and certain obstruction to the metabolism function of the skin.

Many natural plants have strong water retention capacity, and some natural plants can survive in desert areas with dry and high temperature. The plants are utilized to extract the functional components and are applied to cosmetics, so that the good long-acting water retention effect can be achieved, and the purposes of safety and environmental protection can be achieved. Cosmetics containing natural plant moisturizing active ingredients are gaining increasing favor of consumers due to good efficacy, small side effects and higher safety. Therefore, research and development of natural plant moisture-retaining active ingredients applied to cosmetics become an important link for sustainable development of the cosmetic industry.

Disclosure of Invention

The invention aims to solve the defects in the prior art and provide a moisturizing repair composition. The moisturizing and repairing composition has the effects of moisturizing, locking water and long-acting moisturizing, is fresh, cool, not sticky, high in safety, free of stimulation and quick to absorb, and is suitable for various skins.

In order to realize the purpose, the invention adopts the technical scheme that:

a moisturizing repair composition, comprising the following components: artocarpus heterophyllus stem cell extract, hyaluronic acid and ceramide.

Artocarpus heterophyllus (Myrothamnus FLABELLIFOLIA), also known as Phoenix officinalis in south Africa, also known as "regenerated grass" or "revived grass", grows in arid regions in the south of Africa under extreme climatic conditions of no water, high salt and strong sunlight. The growth mechanism of the Artocarpus heterophyllus is as follows: plants accumulate low molecular weight compounds, glycerol glucoside, which maintain the activity of the plant structure, protect the plant from being completely desiccated, protect the cell membrane and specific proteins, and reduce water loss to the external environment by increasing the intracellular osmotic pressure. When raining, glycerol glucoside activates cellular plant function, causing the cells to turn green rapidly. The extract of Michelia Artocarpa stem cells contains high concentration of glycerol glucoside, and has excellent effects in keeping moisture, promoting cell activity, protecting stratum corneum and resisting inflammation. At present, no report of the application of the millettia speciosa stem cell extract to cosmetics appears, and for this reason, the invention creatively applies the millettia speciosa stem cell extract to cosmetics. Experiments prove that the millettia speciosa stem cell extract, the hyaluronic acid and the ceramide interact with each other to achieve a synergistic effect, so that the moisturizing repair effect of the moisturizing repair composition is better.

Preferably, the extract of the millettia speciosa stem cells: hyaluronic acid: the ceramide is 90-120: 20-40: 15-35. Experiments show that when the millettia speciosa stem cell extract, the hyaluronic acid and the ceramide are compounded according to the mass ratio, the moisturizing repair effect and the skin feeling of the moisturizing repair composition are good.

More preferably, the extract of the millettia speciosa stem cells: hyaluronic acid: the ceramide is 100-110: 25-35: 20-30. Experiments show that when the millettia speciosa stem cell extract, the hyaluronic acid and the ceramide are compounded according to the mass ratio, the moisturizing repair effect and the skin feeling of the moisturizing repair composition are better.

Most preferably, the extract of the millettia speciosa stem cells: hyaluronic acid: ceramide 105:30: 25. Experiments show that when the millettia speciosa stem cell extract, the hyaluronic acid and the ceramide are compounded according to the mass ratio, the moisturizing and repairing composition has the best moisturizing and repairing effect and skin feel.

Preferably, the preparation method of the extract of the millettia speciosa stem cells comprises the following steps: taking young and tender parts of the Artocarpus heterophyllus, disinfecting the young and tender parts, culturing by using a solid culture medium to obtain a meristem primordium, performing subculture on the meristem primordium by using a liquid culture medium to obtain Artocarpus heterophyllus stem cells, and finally freezing, drying and crushing the obtained Artocarpus heterophyllus stem cells to obtain the Artocarpus heterophyllus stem cell extract.

Preferably, the preparation method of the extract of the millettia speciosa stem cells comprises the following steps:

(1) pre-treatment: taking young bud tips or stem tips of the Artocarpus heterophyllus, soaking the young bud tips or stem tips of the Artocarpus heterophyllus in 70-75% alcohol for 10-120 s, repeatedly cleaning the young bud tips or stem tips with 5% NaClO solution for three times, and finally, completely washing the young bud tips or stem tips with sterile water.

(2) Inoculating, proliferating and culturing: inoculating the sterilized bud tips or stem tips on a solid culture medium, culturing in a dark box at 25 ℃, subculturing once every two weeks for 2 months to obtain a meristem primordium; the solid culture medium is an MS solid culture medium containing naphthylacetic acid and 6-benzylaminopurine; preferably, the concentration of naphthylacetic acid in the MS solid culture medium is 1.5umol/L, and the concentration of 6-benzylaminopurine is 8 umol/L.

(3) Subculturing: cutting out a fine and separate bud primordium, inoculating the fine and separate bud primordium into a liquid culture medium, then placing the liquid culture medium on a rotary shaking table for shaking culture, replacing the culture medium once every 10 days, and filtering out enlarged and unshaped explants with blackened appearance after 9-10 weeks to obtain small cell clusters; continuously carrying out subculture on the small cell mass by using a liquid culture medium, continuously expanding a culture system, and replacing the culture medium every 2 weeks to obtain Artocarpus heterophyllus stem cells; the liquid culture medium is 1/2MS liquid culture medium containing 2,4-D and ZT; preferably, in the 1/2MS liquid culture medium, the concentration of 2,4-D is 5umol/L, and the concentration of ZT is 1 umol/L.

(4) Prefreezing the Artocarpus millettii stem cells obtained in the step (3) at-25 to-75 ℃ for 2-8 h, then quickly freezing in liquid nitrogen for 2-8 h, and then thawing for 5-90 min; repeating the operation for 2-8 times, standing at room temperature for 5-45 min, and finally crushing to 150-200 meshes to obtain the Artocarpus millettii stem cell extract.

The invention also provides application of the moisturizing and repairing composition in cosmetics.

The invention also provides a cosmetic containing the moisturizing and repairing composition. The cosmetic may be in the form of cream, lotion, pack, essence, etc., but is not limited thereto.

Preferably, the moisture-keeping repair composition accounts for 0.1-10% of the weight of the cosmetic. Experiments show that when the moisturizing and repairing composition is applied to cosmetics in the amount, the moisturizing and repairing effect of the cosmetics can be effectively improved, and the cost can be controlled within a reasonable range.

The invention also provides a moisturizing repair emulsion which comprises the following components in percentage by weight: 0.1-10% of the moisturizing and repairing composition, 2-15% of a humectant, 0.01-1% of an emollient, 0.1-5% of a surfactant, 0.01-2% of a preservative, 0.01-2% of a thickening agent and the balance of deionized water. The moisturizing repair emulsion disclosed by the invention is mild and non-irritant to skin, safe to use, fresh and non-sticky, has excellent quick moisturizing and long-acting moisturizing effects, and is suitable for various skins.

Preferably, the humectant is at least one of glycerin, butylene glycol and dipropylene glycol. When the humectant is at least two of glycerin, butanediol and dipropylene glycol, the components can be mixed in any proportion.

Preferably, the emollient is at least one of avocado oil, jojoba oil. When the emollient is composed of avocado oil and jojoba oil, the avocado oil and jojoba oil can be mixed at any ratio.

Preferably, the surfactant is at least one of sodium lauroyl glutamate, myristic acid, PPG-2 hydroxyethyl cocamide. When the surfactant is at least two of sodium lauroyl glutamate, myristic acid and PPG-2 hydroxyethyl cocoamide, the components can be mixed in any proportion.

Preferably, the preservative is a mixture of a zanthoxylum bungeanum fruit extract, a artemisia leaf extract, a lophatherum gracile extract, a crinkle fruit extract and 1, 2-pentanediol, and the preservative is prepared from the following components in parts by weight: NQ-2016-A, available from the institute of Biochemical technology, Beijing.

Preferably, the thickener is at least one of carbomer and xanthan gum. When the thickening agent consists of carbomer and xanthan gum, the carbomer and the xanthan gum can be mixed in any proportion.

Preferably, the moisturizing repair emulsion comprises the following components in percentage by weight: the moisturizing and repairing composition comprises 5% of a moisturizing agent, 10% of a moisturizing agent, 0.5% of an emollient, 2% of a surfactant, 1% of a preservative, 0.1% of a thickening agent and the balance of deionized water. The moisturizing repair emulsion prepared by the formula has good moisturizing and long-acting moisturizing effects, has the best use skin feeling, is easier to absorb by skin, and is fresh and not sticky.

Preferably, the preparation method of the moisturizing repair emulsion comprises the following steps:

(1) adding the humectant, the thickener and the emollient into an emulsifying pot, adding deionized water, stirring at 75-85 ℃ until the mixture is uniformly mixed, and carrying out heat preservation and sterilization to obtain a mixed solution A;

(2) and when the temperature of the mixed solution A is reduced to 50 ℃, sequentially adding the surfactant and the preservative, continuously stirring until the mixed solution A is uniform, when the temperature is reduced to room temperature, adding the moisturizing repair composition, and continuously stirring until the mixed solution A is uniform to prepare the moisturizing repair emulsion.

Compared with the prior art, the invention has the beneficial effects that: the invention creatively applies the millettia stem cell extract to cosmetics, and prepares the moisturizing repair composition by compounding the millettia stem cell extract, hyaluronic acid and ceramide. Experiments prove that the moisturizing and repairing composition has the effects of moisturizing, locking water and preserving moisture for a long time, is fresh, cool, not sticky, high in safety, free of stimulation and quick to absorb, and is suitable for various skins. The extract of the Artocarpus heterophyllus stem cells, the hyaluronic acid and the ceramide can interact with each other to generate a synergistic effect, so that the moisturizing repair composition has a better moisturizing repair effect. The invention also provides a formula for enabling the moisturizing and repairing composition to achieve better effects in the aspects of moisturizing and using skin feel, and also provides a preferable formula for applying the moisturizing and repairing composition to emulsion.

Detailed Description

To better illustrate the objects, aspects and advantages of the present invention, the present invention is further illustrated by the following examples. It should be understood that the embodiments of the present invention are only for illustrating the technical effects of the present invention, and are not intended to limit the scope of the present invention. In the examples, the methods used were all conventional methods unless otherwise specified.

Example 1

This example 1 provides a moisturizing and repairing composition, which is composed of the following components in parts by weight: 105 parts of Artocarpus heterophyllus stem cell extract, 30 parts of hyaluronic acid and 25 parts of ceramide.

Example 2

This example 2 provides a moisturizing and repairing composition, which is composed of the following components in parts by weight: 110 parts of Artocarpus heterophyllus stem cell extract, 25 parts of hyaluronic acid and 20 parts of ceramide.

Example 3

The embodiment 3 provides a moisturizing and repairing composition, which is composed of the following components in parts by weight: 100 parts of Artocarpus heterophyllus stem cell extract, 35 parts of hyaluronic acid and 30 parts of ceramide.

Example 4

The embodiment 4 provides a moisturizing and repairing composition, which is composed of the following components in parts by weight: 90 parts of Artocarpus heterophyllus stem cell extract, 40 parts of hyaluronic acid and 35 parts of ceramide.

Example 5

This example 5 provides a moisturizing repair composition, which is composed of the following components in parts by weight: 120 parts of Artocarpus heterophyllus stem cell extract, 20 parts of hyaluronic acid and 15 parts of ceramide.

Example 6

The embodiment 6 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 1, 5% butylene glycol, 10% jojoba oil, 0.5% PPG-2 hydroxyethyl cocamide, 2% NQ-2016-a preservative, 1% carbomer, 0.1%, and the balance deionized water.

Example 7

This example 7 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 2, 5% butylene glycol, 10% jojoba oil, 0.5% PPG-2 hydroxyethyl cocamide, 2% NQ-2016-a preservative, 1% carbomer, 0.1%, and the balance deionized water.

Example 8

This example 8 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 3, 5% butylene glycol, 10% jojoba oil, 0.5% PPG-2 hydroxyethyl cocamide, 2% NQ-2016-a preservative, 1% carbomer, 0.1%, and the balance deionized water.

Example 9

This example 9 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 4, 10% glycerin, 1% dipropylene glycol, 0.01% avocado oil, 0.1% sodium lauroyl glutamate, 2% NQ-2016-a preservative, 0.01% xanthan gum, and the balance deionized water.

Example 10

The embodiment 10 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 5, 8% butylene glycol, 3% glycerin, 2% avocado oil, 0.1% myristic acid, 0.5% sodium lauroyl glutamate, 1.5% NQ-2016-a preservative, 0.05% xanthan gum, and the balance deionized water.

Example 11

This example 11 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 3%, glycerin 3%, butylene glycol 6%, dipropylene glycol 3%, avocado oil 0.4%, jojoba oil 0.4%, sodium lauroyl glutamate 0.5%, myristic acid 0.5%, PPG-2 hydroxyethyl cocamide 2%, NQ-2016-a preservative 0.5%, carbomer 0.5%, and the balance deionized water.

Example 12

This example 12 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 2 1%, butylene glycol 10%, glycerin 5%, jojoba oil 1%, PPG-2 hydroxyethyl cocamide 4%, NQ-2016-a preservative 0.2%, carbomer 1%, xanthan gum 0.5%, and the balance deionized water.

Example 13

This example 13 provides a moisturizing repair emulsion, which is composed of the following components in percentage by weight: the moisturizing repair composition of example 1, 0.1%, butylene glycol 10%, dipropylene glycol 5%, avocado oil 1%, sodium lauroyl glutamate 5%, NQ-2016-a preservative 0.01%, carbomer 2%, and the balance deionized water.

Example 14

The embodiment provides a preparation method of the moisturizing repair emulsion of embodiments 6 to 13, which includes the following steps:

(1) adding a humectant, a thickening agent and an emollient into an emulsifying pot, adding deionized water, stirring at the rotation speed of 1000-1500 r/min at the temperature of 75-85 ℃ until the materials are uniformly mixed, and preserving heat for 30min for sterilization to obtain a mixed solution A;

(2) and when the temperature of the mixed solution A is reduced to 50 ℃, sequentially adding a surfactant and a preservative, continuously stirring at the rotating speed of 1000-1500 r/min for 20min to uniformly mix the materials, continuously reducing the temperature to room temperature, adding the moisturizing and repairing composition, and continuously stirring until the materials are uniform.

Example 15

This example provides a method for preparing an extract from the stem cells of Artocarpus heterophyllus used in the above examples, which comprises the following steps:

(1) pre-treatment: soaking tender stem tips of Artocarpus mollis in 70% ethanol for 60s, repeatedly cleaning with 5% NaClO solution for three times, and washing with sterile water.

(2) Inoculating, proliferating and culturing: inoculating the sterilized stem tip on a solid culture medium, culturing in a dark box at 25 ℃, subculturing once every two weeks for 2 months to obtain a meristem primordium; the solid culture medium is an MS solid culture medium containing naphthylacetic acid and 6-benzylaminopurine; in the MS solid culture medium, the concentration of the naphthylacetic acid is 1.5umol/L, and the concentration of the 6-benzylaminopurine is 8 umol/L.

(3) Subculturing: cutting fine and separate bud primordium, inoculating into liquid culture medium, placing on rotary shaking table, shaking and culturing, changing culture medium every 10 days, and filtering out large and unshaped explant with blackened appearance after 10 weeks to obtain small cell mass; continuously carrying out subculture on the small cell mass by using a liquid culture medium, continuously expanding a culture system, and replacing the culture medium every 2 weeks to obtain Artocarpus heterophyllus stem cells; the liquid culture medium is 1/2MS liquid culture medium containing 2,4-D and ZT; preferably, in the 1/2MS liquid culture medium, the concentration of 2,4-D is 5umol/L, and the concentration of ZT is 1 umol/L.

(4) Prefreezing the Artocarpus millettii stem cells obtained in the step (3) at-50 ℃ for 5h, then quickly freezing in liquid nitrogen for 4.5h, and then thawing for 40 min; repeating the above operations for 5 times, standing at room temperature for 30min, and pulverizing to 200 mesh to obtain the Michelia Arboriana stem cell extract.

Comparative example 1

The moisturizing repair emulsion comprises the following components in percentage by weight: 10.5% of butanediol, 0.5% of jojoba oil, 2.1% of PPG-2 hydroxyethyl cocamide, 1.1% of NQ-2016-A preservative, 0.1% of carbomer and the balance of deionized water.

Comparative example 2

The moisturizing repair emulsion comprises the following components in percentage by weight: 5% of moisturizing and repairing composition, 10% of butanediol, 0.5% of jojoba oil, 2% of PPG-2 hydroxyethyl cocamide, 1% of NQ-2016-A preservative, 0.1% of carbomer and the balance of deionized water.

The moisturizing and repairing composition comprises the following components in parts by weight: 30 parts of hyaluronic acid and 25 parts of ceramide.

Comparative example 3

The moisturizing repair emulsion comprises the following components in percentage by weight: 5% of moisturizing and repairing composition, 10% of butanediol, 0.5% of jojoba oil, 2% of PPG-2 hydroxyethyl cocamide, 1% of NQ-2016-A preservative, 0.1% of carbomer and the balance of deionized water.

The moisturizing and repairing composition comprises the following components in parts by weight: 105 parts of Artocarpus heterophyllus stem cell extract and 25 parts of ceramide.

Comparative example 4

The moisturizing repair emulsion comprises the following components in percentage by weight: 5% of moisturizing and repairing composition, 10% of butanediol, 0.5% of jojoba oil, 2% of PPG-2 hydroxyethyl cocamide, 1% of NQ-2016-A preservative, 0.1% of carbomer and the balance of deionized water.

The moisturizing and repairing composition comprises the following components in parts by weight: 105 parts of Artocarpus heterophyllus stem cell extract and 30 parts of hyaluronic acid.

Comparative examples 1-4 methods of making moisturizing repair emulsions reference example 14.

Firstly, safety test

The moisturizing repair compositions of examples 1 to 5, the moisturizing repair emulsions of examples 6 to 13, and the moisturizing repair emulsions of proportions 1 to 4 were evaluated for cosmetic irritation using "technical standards for cosmetic safety" in 2015 as a reference standard, and the test method was a skin patch test in which 85 persons aged 16 to 65 years were randomly distributed.

The test method comprises the following steps: putting the tested object into a spot tester with the dosage of about 0.020-0.025 g, sticking the spot tester with the tested object on the back or the bent side of the forearm of the tested object by using a non-irritating adhesive tape, and lightly pressing with the palm to uniformly stick the spot tester on the skin for 24 hours. And (5) removing the tested spot tester for 30min, and observing skin reaction after the indentation disappears. If the result is negative, the test is observed once more at 24h and 48h after the patch test.

Evaluation criteria: level 0: negative reaction; level 1: suspicious reactions, only faint erythema; and 2, stage: weak positive reaction, erythema, infiltration, edema, and possibly pimple; and 3, level: strong positive reaction, erythema, infiltration, edema, pimple and reaction beyond the tested area; 4, level: very strong positive reaction, obvious erythema, severe infiltration, edema, herpes fusiformis and reaction beyond the tested area.

And (3) testing results: skin reactions were negative in all subjects.

The test results show that the moisturizing repair composition and the moisturizing repair emulsion provided by the invention are mild and non-irritant to skin and are safe to use.

Second, testing the moisturizing effect

Skin stratum corneum hydration test: the working principle is that the capacitor is used as an instrument probe, and as water is a substance with the largest dielectric constant on the skin, when the moisture content of the skin changes, the capacitance value of the skin also changes, so that the moisture content on the surface of the skin can be analyzed by measuring the capacitance value of the skin. A commonly used instrument is Corneometer CM 825. The moisture-retaining efficacy of the cosmetic was evaluated by measuring the change in the water content of the stratum corneum by measuring the change in the capacitance of the stratum corneum before and after application of the product. The method quantifies the moisture content of the horny layer of the skin, can sensitively reflect the change of the moisture content of the skin, has good reproducibility, and is one of the common methods for evaluating the efficacy of the current moisturizing cosmetics.

The experimental method comprises the following steps: marking out 3X 3cm on the bent side of the left and right forearms of the person to be tested²And (3) in a square experiment area with the size, taking the left arm as a test area of the moisturizing product, taking a corresponding symmetrical area of the right arm as a blank control, testing and detecting the moisture content of each test part by using a Corneometer CM825, and repeating for 5 times respectively to obtain an average value. The hydration rate was calculated by the formula (1).

Moisturizing effect tests were performed on the moisturizing repair emulsions of examples 6 to 13 and the moisturizing repair emulsions of comparative examples 1 to 4, and the results are shown in table 1.

TABLE 1 moisturizing effect

And (4) analyzing results:

1. from the results of examples 6 to 13, it can be seen that the moisturizing repair emulsion provided by the embodiment of the invention has a good moisturizing effect, and particularly, the effect of examples 6 to 8 is good, which indicates that different amounts of the components in the emulsion formula may affect the moisturizing effect of the emulsion to a certain extent. In examples 6 to 8, the best effect of example 6 is shown, and when the mass ratio of the millettia speciosa stem cell extract, hyaluronic acid and ceramide is 105:30:25, the moisturizing efficacy of the moisturizing repair composition is the best.

2. The results of comparing examples 6-13 with comparative example 1 show that the moisturizing repair composition provided by the invention can effectively improve the moisturizing effect of the emulsion.

3. The results of the comparison of the example 6 and the comparative examples 2 to 4 show that the composition of the millettia speciosa stem cell extract, the hyaluronic acid and the ceramide has a synergistic effect, and the moisturizing effect of the moisturizing repair emulsion is remarkably improved.

Skin feel evaluation

Skin feel evaluation was performed on the emulsions of examples 6 to 13 and comparative examples 1 to 4.

The method comprises the following steps: the samples of each example and comparative example were each comparative scored by 10 skin-feel panelists using a double-blind, random comparative test. The test method was to evaluate the product on the back of the hand (circle of about 5cm diameter is the evaluation area) with 50. mu.L each of the left and right backs of the hand. And (4) scoring the skin feel of each stage by referring to the scale of the standard substance, removing the maximum value and the minimum value of the score, and taking a mean value. The sensory evaluation parameters and the scoring criteria are referred to table 2, and the evaluation results are shown in table 3.

TABLE 2 sensory evaluation parameters and Scoring standards

Table 3 evaluation results

And (4) analyzing results: as can be seen from the evaluation results in Table 3, the emulsions of the examples of the present invention were evaluated in all the evaluation items, and among them, the emulsions of examples 6 to 10 had desirable skin feel, good moisturizing effect, refreshing feeling after use, no stickiness, and quick absorption.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (12)

1. A moisturizing repair composition, comprising the following components: artocarpus heterophyllus stem cell extract, hyaluronic acid and ceramide; the extract of the Artocarpus heterophyllus stem cells comprises the following components in percentage by mass: hyaluronic acid: ceramide =105:30: 25; the preparation method of the Artocarpus heterophyllus stem cell extract comprises the following steps: sterilizing tender parts of the Artocarpus heterophyllus, culturing by using a solid culture medium to obtain a meristem primordium, performing subculture on the meristem primordium by using a liquid culture medium to obtain Artocarpus heterophyllus stem cells, and freeze-drying and crushing the obtained Artocarpus heterophyllus stem cells to obtain the Artocarpus heterophyllus stem cell extract; the solid culture medium is an MS solid culture medium containing naphthylacetic acid and 6-benzylaminopurine; in the MS solid culture medium, the concentration of naphthylacetic acid is 1.5 mu mol/L, and the concentration of 6-benzylaminopurine is 8 mu mol/L; the liquid culture medium is 1/2MS liquid culture medium containing 2,4-D and ZT; in the 1/2MS liquid culture medium, the concentration of 2,4-D is 5 mu mol/L, and the concentration of ZT is 1 mu mol/L.

2. Use of the moisturizing repair composition of claim 1 in the preparation of a cosmetic.

3. A cosmetic comprising the moisturizing repair composition of claim 1.

4. The cosmetic of claim 3, wherein the moisturizing repair composition is present in the cosmetic in an amount of 0.1% to 10% by weight.

5. The moisturizing repair emulsion is characterized by comprising the following components in percentage by weight: the moisturizing and repairing composition as claimed in claim 1, wherein the moisturizing and repairing composition comprises 0.1% -10%, 2% -15% of a humectant, 0.01% -1% of an emollient, 0.1% -5% of a surfactant, 0.01% -2% of a preservative, 0.01% -2% of a thickener and the balance of deionized water.

6. The moisturizing repair emulsion of claim 5 wherein the humectant is at least one of glycerin, butylene glycol, dipropylene glycol.

7. The moisturizing repair emulsion of claim 5 wherein the emollient is at least one of avocado oil and jojoba oil.

8. The moisturizing repair emulsion of claim 5 wherein the surfactant is at least one of sodium lauroyl glutamate, myristic acid, PPG-2 hydroxyethyl cocamide.

9. The moisturizing repair emulsion of claim 5, wherein the preservative is a mixture of a zanthoxylum bungeanum fruit extract, a artemisia argyi leaf extract, a lophatherum gracile extract, a crinkle fruit extract, and 1, 2-pentanediol.

10. The moisturizing repair emulsion of claim 5 wherein the thickener is at least one of carbomer, xanthan gum.

11. The moisturizing repair emulsion of claim 5, comprising the following components in weight percent: the moisturizing repair composition of claim 1, 5% of a moisturizer 10%, 0.5% of an emollient, 2% of a surfactant, 1% of a preservative, 0.1% of a thickener, and the balance deionized water.

12. The method of preparing a moisturizing repair emulsion of claim 5 comprising the steps of:

(1) adding the humectant, the thickener and the emollient into an emulsifying pot, adding deionized water, stirring at 75-85 ℃ until the mixture is uniformly mixed, and carrying out heat preservation and sterilization to obtain a mixed solution A;

(2) and when the temperature of the mixed solution A is reduced to 50 ℃, sequentially adding the surfactant and the preservative, continuously stirring until the mixed solution A is uniform, when the temperature is reduced to room temperature, adding the moisturizing repair composition, and continuously stirring until the mixed solution A is uniform to prepare the moisturizing repair emulsion.