CN109316419A - A kind of the plant composition fermentation magma and preparation and application of balance skin Tiny ecosystem - Google Patents
A kind of the plant composition fermentation magma and preparation and application of balance skin Tiny ecosystem Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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Abstract
The invention discloses a kind of plant composition of balance skin Tiny ecosystem fermentation magma and preparation and application.Plant composition fermentation magma is rationally compounded according to the Chinese medicine side of the sending principle of " monarch ", choose semen coicis, radix polygonati officinalis, centella, schizonepeta, cactus best prescription on the basis of, then through optimize repeatedly fermentation extract test obtain best preparation method made from；Plant composition fermentation magma promotes skin health for can effectively maintain skin microecological balance in cosmetics；Manufactured cosmetics energy balance skin Tiny ecosystem promotes the growth of skin beneficial bacterium, inhibits the activity of harmful bacteria, adjust the fat secretion of skin, inhibits the generation of acne, reduces skin susceptibility.
Description
Technical field
The present invention relates to cosmetic field, relate generally to a kind of balance skin Tiny ecosystem plant composition fermentation magma and
Preparation and application.
Background technique
Skin is the natural barrier of mankind's body surface, and there is many microorganisms, skin microecological balance remains skin ring
The stabilization in border plays an important role to the health of body.
Under the conditions of normal colony balance, a large amount of beneficial bacteriums of skin surface play the effect for protecting skin health.
Probiotics is had the advantage, and change ring by own metabolism after the privileged site growth of skin surface in nutrient competition
The pH value or release antibiotic in border generate Ant agonism to other floras to inhibit the growth of harmful bacteria and foreign bacteria.
The skins excreta such as inorganic salts, uric acid and urea can also be absorbed and utilized in probiotics, and heavy metal ion pair is resisted on balance skin surface
The infringement of cell, water conservation moisturizing etc..When skin is invaded and harassed, the quantity of skin resident bacteria and/or tabernacle bacterium will increase severely, and lead
Cause skin flora disorder, thus will appear the vigorous, scytitis of skin oil and fat secretion, comedo and acne, dandruff head itch etc. it is a series of
Skin problem.
If a kind of nutritional ingredient can be provided for skin, promotes the growth of skin beneficiating bacterium and inhibit skin harmful bacteria
Breeding can maintain skin pH value, maintain the balance of moisture of skin and nutrient, eliminate sensitive and inflammation, enhance the barrier of skin.
Currently, the active matter for balance skin Tiny ecosystem has become the hot spot of cosmetic field research.
Chinese invention patent CN201710604164.9 discloses a kind of with maintenance and recovery skin Tiny ecosystem work
Composition and preparation method thereof, it is characterised in that including following components trunk natural sap, fresh squeezing fruit syrup, special carbohydrate
With different malt, the composition has the effect of generation that is anti-inflammatory, promoting antibacterial peptide, can safeguard and restore the strong of skin Tiny ecosystem
Health.
Chinese invention patent CN201310469004.X disclose a kind of composition that can promote skin microecological balance and
Preparation method, the composition are mentioned with skin prebiotics alpha-glucans oligosaccharides, fructooligosaccharide, beta glucan, plant extracts, yeast
Take object and the bright string coccus of natural antibacterial agent/radish root tunning filtrate as the main component, the composition fundamentally adjusts skin
Microecological balance, the Maintenance Of Skin Health, overcome Traditional makeup/skin care item it is palliative and be also easy to produce side effect lack
It falls into.
The present invention is exactly to comply with the trend of cosmetics development, provides one kind safely, effectively from skin microecological balance angle
Plant composition used for cosmetic ferment magma, have broad application prospects and huge market value.
Summary of the invention
The present invention provides a kind of plant composition of balance skin Tiny ecosystem fermentation magma and preparation method, the proferments
Slurry has effects that maintain skin Tiny ecosystem.
In order to reach this purpose, following technical solution is used
A kind of plant composition magma of balance skin Tiny ecosystem is made of the component of following parts by weight, 5-50 parts of semen coicis,
5-40 parts of radix polygonati officinalis, 5-30 parts of centella, 5-30 parts of schizonepeta, 5-30 parts of cactus.
Preferably, the plant composition magma (I) of a kind of balance skin Tiny ecosystem, by the component including following parts by weight
It is made, 20-40 parts of semen coicis, 20-25 parts of radix polygonati officinalis, 15-20 parts of centella, 10-20 parts of schizonepeta, 10-20 parts of cactus.
Preferably, a kind of plant composition magma of balance skin Tiny ecosystem is made of the component of following parts by weight, the heart of a lotus seed
35 parts of the seed of jog's tears, 25 parts of radix polygonati officinalis, 15 parts of centella, 15 parts of schizonepeta, 10 parts of cactus.
Preferably, the plant composition magma (II) of a kind of balance skin Tiny ecosystem, by the group including following parts by weight
Divide and is made, 40 parts of semen coicis, 20 parts of radix polygonati officinalis, 15 parts of centella, 10 parts of schizonepeta, 15 parts of cactus.
Preferably, the plant composition magma (III) of a kind of balance skin Tiny ecosystem, by the group including following parts by weight
Divide and is made, 30 parts of semen coicis, 20 parts of radix polygonati officinalis, 15 parts of centella, 15 parts of schizonepeta, 20 parts of cactus.
Preferably, the plant composition magma (IV) of a kind of balance skin Tiny ecosystem, by the group including following parts by weight
Divide and is made, 20 parts of semen coicis, 20 parts of radix polygonati officinalis, 20 parts of centella, 20 parts of schizonepeta, 20 parts of cactus.
The preparation method of the plant composition fermentation magma uses fermentation extraction method, i.e., carries out plant composition
After fermentation process, ferment using filter, the plant composition for sterilizing and centrifugal separation, decolourizing, balance skin Tiny ecosystem being obtained by filtration
Magma.Specifically comprise the following steps:
1. bacterium used in the fermentation is Lactococcus lactis, fermentation bacteria used thereby is added in the form of bacterium solution, and bacterial concentration is
105-108cfu/mL；
2. stock: by the removal of impurities of each plant material, cleaning, being crushed to 20-200 mesh, mix, obtain plant composition；Compound concentration
It is 105-108 The bacterium solution of cfu/mL, pH value are adjusted to 6.5-7.5；
3. fermentation: according to the ratio mixing bacterium solution, plant composition and water, ferment 40- in 28-45 DEG C, 50-300r/min condition
72 hours, obtain fermentation liquid；
4. purification: by gained filtering fermentation liquor, at a temperature of high pressure sterilization 20-40min of the filtrate at 105-125 DEG C；After sterilizing
Ferment filtrate be centrifuged 10-35min under conditions of 3000-8000r/min, centrifugation radius are 5-20cm, precipitating is abandoned, in collection
Clear liquid, with active carbon decoloring, filtrate, as the plant composition fermentation magma of balance skin Tiny ecosystem are collected in filtering.
Preferably, step 2. in, be crushed to 60 mesh.
Preferably, step 3. in, ferment 60 hours in 30-40 DEG C, 50r/min condition, obtain fermentation liquid；
The amount ratio of the bacterium solution, plant composition and water is 5mL-30mL:15g-60g:200-600g.
Preferably, the amount ratio of the bacterium solution, plant composition and water is 8mL-20mL:25g-50g:300-500g.
Preferably, the plant composition of the balance skin Tiny ecosystem ferments magma (I), bacterium solution, plant composition and water
Amount ratio be 10mL:20g:300g.
Preferably, the plant composition of the balance skin Tiny ecosystem ferments magma (II), bacterium solution, plant composition and water
Amount ratio be 15mL:30g:420g.
Preferably, the plant composition of the balance skin Tiny ecosystem ferments magma (III), bacterium solution, plant composition and water
Amount ratio be 12mL:25g:400g.
Preferably, the plant composition of the balance skin Tiny ecosystem ferments magma (IV), bacterium solution, plant composition and water
Amount ratio be 12mL:24g:380g.
Preferably, step 4. in, at a temperature of high pressure sterilization 30min of the filtrate at 110-115 DEG C；By the fermentation filter after sterilizing
Liquid is centrifuged 20-40min under conditions of 3000-5000r/min, centrifugation radius are 8-12cm, abandons precipitating, collects supernatant.
Second object of the present invention is that the plant composition fermentation magma is applied in cosmetics, provides one kind
The cosmetics of balance skin Tiny ecosystem.
In order to reach this purpose of the invention, this invention takes following technical solutions:
The described plant composition fermentation magma is being made up preparing the application in cosmetics, the plant composition fermentation magma
Additive amount in product is 0.1-100% based on mass fraction.
The present invention also provides a kind of cosmetics of balance skin Tiny ecosystem effect, which contains above-mentioned plant composition
Fermentation magma.
The cosmetics contain the above-mentioned plant composition fermentation magma for 0.1~100% based on mass fraction.
The cosmetics are as follows: aqua, type of latex type, cream kind, mask class, gel class, powder class, spray-like, essence class,
Wash shield class.
Mechanism of the invention is:
A kind of plant composition fermentation magma of balance skin Tiny ecosystem of the invention is theoretical with the traditional Chinese medical science prescription of monarch
For guidance, obtained through a large amount of experimental study of inventor.In the present invention, inventor is deep in long-term production research process
Enter to excavate in traditional plant have maintenance releive, antiallergic anti-inflammatory, red antipruritic effective type of dispelling, with " monarch " in Chinese medicine
The side's of sending principle rationally compounds, on the basis of the best prescription for choosing radix polygonati officinalis, aloe, Radix Ophiopogonis, the bletilla striata, cactus, then through repeatedly excellent
The fermentation of change is extracted made from the best preparation method that test obtains.
In plant prescription of the invention, using semen coicis as monarch drug in a prescription, semen coicis slightly sweet flavor is slightly cold, there is inducing diuresis for removing edema, invigorating the spleen
It dries, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus and other effects, is rich in amino acid, Coixol, Coixenolide, triterpenoid, protein, carbon water
Compound, vitamin B1 etc. have the effects that dispel acne, nti-freckle and improvement chapped skin, pachylosis.Using centella as minister
Medicine, centella have effects that removing toxicity for detumescence, antibacterial anti-inflammatory, are rich in asiaticosid, have treatment skin ulcer, promote skin raw
Long effect.Using radix polygonati officinalis and schizonepeta as adjutant, radix polygonati officinalis has yin-nourishing, moisturizes, heat-clearing, promotes the production of body fluid, cough-relieving and other effects, rich in
Fragrant solomonseal rhizome polyoses, moistening effect are significant；Schizonepeta has inducing sweat and dispelling exogenous evils, declares malicious promoting eruption and blood anastalsis, is used for rubeola pruigo, rash
Impermeable out, sore etc. can promote skin blood circulation to reinforce and promote the healing of skin infection disease and the suction of disease damage tissue
Adduction.It is to make medicine with cactus, cactus nature and flavor slight bitter, slightly cold, energy expelling wind and removing dampness, scattered stasis pain, with stronger antibacterial
And antiviral efficacy, moreover it is possible to promote skin wound healing acceleration, cactus flavones also inhibits tyrosinase activity, removes oxygen certainly
It the effect of by base, can skin whitening face nourishing antidebilitation.The above all medicines share, drug effect is mutually coordinated, can reach moisturizing and nutrition flesh
The effect of skin promotes skin wound healing, kills pathogenic bacteria and fungi, maintain skin health, while also there is certain beauty
Hold beauty treatment effect.
Compared with prior art, the present invention has the advantage that
(1) each plant rationally compounds according to " monarch " side of sending principle, can be synergistic, and maximum plays the beauty treatment function of raw material
Effect, more comprehensively than single plant effect.
(2) preparation process recovery rate provided by the invention is high, and the advantage using fermentation extraction method is effectively to simplify production
Technique carries out reaction process under mild conditions.Meanwhile ferment extraction method can with feed change component molecules structure,
Raw material effect is promoted, reduces toxicity and irritation, the advantages such as optimization color, taste, are a kind of new works of comparatively ideal plant extract
Skill is conducive to promote and apply.
(3) it is used in cosmetics plant composition fermentation magma of the invention that can effectively maintain skin microecological balance,
Promote skin health；Skin water and oil balance is adjusted in product, keeps skin slip delicate；It releives sensitivity, enhances skin barrier；It is also right
The generation and recurrence of acne have certain inhibiting effect.
Specific embodiment
Further to illustrate technological means and its effect adopted by the present invention, below in conjunction with preferred implementation of the invention
Example to further illustrate the technical scheme of the present invention, but the present invention is not limited in scope of embodiments.
A kind of plant composition magma (I) and preparation method thereof of the balance skin Tiny ecosystem of embodiment 1
A kind of plant composition magma of balance skin Tiny ecosystem is made: semen coicis 35 of the component for including following parts by weight
Part, 25 parts of radix polygonati officinalis, 15 parts of centella, 15 parts of schizonepeta, 10 parts of cactus.
The preparation method is as follows:
1. compound concentration is 105-108 The bacterium solution of cfu/mL, pH value are adjusted to 6.5-7.5；
2. stock: by the removal of impurities of each plant material, cleaning, being crushed to 60 mesh, mix, obtain plant composition；
3. fermentation: by bacterium solution, plant composition and water, 10mL:20g:300g is mixed according to the ratio, in 30-40 DEG C, 100r/min item
It ferments 48 hours in part, obtains fermentation liquid；
4. purification: by gained filtering fermentation liquor, at a temperature of high pressure sterilization 30min of the filtrate at 115 DEG C；By the fermentation filter after sterilizing
Liquid is centrifuged 25min under conditions of 4000r/min, centrifugation radius are 10cm, abandons precipitating, collects supernatant, with active carbon decoloring,
Filtrate is collected in filtering, and the as plant composition ferments magma (I).
A kind of plant composition magma (II) of the balance skin Tiny ecosystem of embodiment 2
A kind of plant composition magma of balance skin Tiny ecosystem is made: semen coicis of the plant component for including following parts by weight
40 parts, 20 parts of radix polygonati officinalis, 15 parts of centella, 10 parts of schizonepeta, 15 parts of cactus.
Preparation method is other than " bacterium solution, plant composition and water according to the ratio 15mL:30g:420g mix ", remaining and implementation
Example 1 is consistent, and plant composition fermentation magma (II) of balance skin Tiny ecosystem provided by the invention is made.
A kind of plant composition magma (III) of the balance skin Tiny ecosystem of embodiment 3
A kind of plant composition magma of balance skin Tiny ecosystem is made: semen coicis of the plant component for including following parts by weight
30 parts, 20 parts of radix polygonati officinalis, 15 parts of centella, 15 parts of schizonepeta, 20 parts of cactus.
Preparation method is other than " bacterium solution, plant composition and water according to the ratio 12mL:25g:400g mix ", remaining and implementation
Example 1 is consistent, and plant composition fermentation magma (III) of balance skin Tiny ecosystem provided by the invention is made.
A kind of plant composition magma (IV) of the balance skin Tiny ecosystem of embodiment 4
A kind of plant composition magma of balance skin Tiny ecosystem is made: semen coicis of the plant component for including following parts by weight
20 parts, 20 parts of radix polygonati officinalis, 20 parts of centella, 20 parts of schizonepeta, 20 parts of cactus.
Preparation method is other than " bacterium solution, plant composition and water according to the ratio 12mL:24g:380g mix ", remaining and implementation
Example 1 is consistent, and plant composition fermentation magma (IV) of balance skin Tiny ecosystem provided by the invention is made.
The single plant fermented liquid of comparative example 1-5
100 parts of plant semen coicis, 100 parts of radix polygonati officinalis, 100 parts of centella, 100 parts of schizonepeta, 100 parts of cactus are weighed respectively.According to
Preparation method described in embodiment 1 carries out fermentation extraction, and single plant fermented liquid is successively made respectively.
6 plant composition extracting solution of comparative example
According to the consistent plant composition dosage of embodiment 1, i.e., plant composition is by the plant material component including following weight
It is made: radix polygonati officinalis 30%, aloe 20%, Radix Ophiopogonis 20%, the bletilla striata 15%, cactus 15%.
Preparation method: by each plant material removal of impurities, cleaning, be crushed to 60 mesh, by liquid material mass ratio be 15:1 addition go from
Sub- water carries out room temperature extraction with high pressure homogenization method machine, after extracting solution is centrifuged, takes supernatant, with work after impregnating 2.5h
Property carbon decoloring, filtering, collect filtrate, be made plant composition extracting solution.
The test of 1 skin microecological balance of test example
The preparation of 1.1 samples
The test medium of embodiment 1, comparative example 1-6 and 0.5% commercial glucose that compound concentration is 0.5% respectively compare and are situated between
Matter.
1.2 experimental principle
Experiment will compare test to absorption rate of the skin flora to specific sample and common glucose sugar, to study
Specific probiotics nutrient is by the consumption process of skin flora.
1.3 experimental method
A part of flora of skin surface is taken to be transplanted in following embodiment, comparative example and contrast medium respectively, test 48 is small
Shi Hou calculates remaining glucose/Phytoplasm nutritional ingredient amount.
Measurement standard is as shown in table 1 below.
1 consumption measurement standard of table
| Consumption level | Consumption state |
| 0-20% | No consumption |
| 20-40% | Consumption degree is poor |
| 40-60% | Medium consumption degree |
| 60-100% | Up to all consumption |
1.4 experimental result
Experimental result is shown in Table shown in 2.
The comparison of 2 actual consumption amount of table
Common glucose is to all same absorption rate with higher of either pathogen or probiotics, and plant society
Object fermentation magma, single plant fermentation product, plant composition extracting solution can with biological selectivity be protected and by skin surface
Probiotics utilize, without being significantly metabolized by pathogen, opposite pathogen is as existing for biostatic agent, wherein
The biological selectivity of plant composition fermentation magma is stronger, confirms that other embodiments also have similar effect through experimental test.
The competitive growth test of test example 2
The preparation of 2.1 samples
The test medium (tryptone USP) of compound concentration is 0.5% respectively embodiment 1, comparative example 1-6.
2.2 experimental principle
Specified plant composition fermentation magma, single plant fermentation magma, plant composition extracting solution are tested in probiotics and disease
Influence and effect when opportunistic pathogen exists simultaneously to the flora condition of production.
2.3 experimental method
By flora the embodiment 1 containing 0.5%, comparative example 1-6 test medium (tryptose arteries and veins USP) in cultivate, 24
Number of bacteria is calculated after hour.
Blending agent: kirschner library micrococcus luteus and staphylococcus aureus.
2.4 experimental result
Experimental result is shown in Table shown in 3.
The competitive test result of table 3
Experimental data shows, plant composition ferments magma, single plant fermentation magma, the nutrition in plant composition extracting solution
Element can promote the growth of probiotics, will not then promote its growth to pathogen, pathogen can be made due to a lack of food and battalion instead
It supports and quantity gradually decreases, play the role of selectivity is utilized by probiotics, and inhibits pathogen；Wherein, the plant of embodiment
Composition fermentation promotion of the magma to probiotics and the inhibitory effect to pathogen are better than single plant fermentation magma, plant society
Object extracting solution confirms that other embodiments also have similar effect through experimental test.
3 irritation evaluation experimental of test example
Fermentation liquid irritation is evaluated using rabbit erythrocyte hemolytic experiment.Concrete operations are as follows: Example 1 and comparative example 1- respectively
The 500 μ L of sample of 6 preparations is placed in 2mL centrifuge tube, then is separately added into 2% rabbit erythrocyte (commercially available) suspension, 500 μ L, and jog mixes,
It is placed in 37 DEG C of constant incubators after incubating 3h, 2000r/min is centrifuged 3min, and Aspirate supernatant is negative right with physiological saline
According to using distilled water as positive control, measurement light absorption value, is calculated by formula haemolysis degree at wavelength 414nm.The results are shown in Table 4.
4 haemolysis degree result of table
Experimental result comparison shows that plant composition fermentation magma haemolysis ratio of the invention is more single than made from comparative example 1-5
The fermentation liquid of plant is much lower, significantly reduces by the irritation of prescription post-fermentation liquid.Also lower than comparative example 6 simultaneously, illustrate to pass through
Plant composition moderate stimulation ingredient decreases after everfermentation processing.
1 plant composition of Application Example fermentation magma lotion
A kind of lotion of the balance skin Tiny ecosystem containing plant composition fermentation magma, the specific formula of the lotion such as 5 institute of table
Show.
Table 5
Above-mentioned emulsion, preparation method are as follows:
1, addition phase raw material parahydroxyacet-ophenone is dissolved by heating in 1,2- hexylene glycol to clear in advance, it is spare；
2, water phase is put into emulsion pot, is stirred evenly, heating stirring is to 75-85 DEG C；
3, oil is mutually put into oil mutually to prepare in pot, is stirred evenly, heating stirring is to 75-85 DEG C；
4, material in oily phase pot is pumped into emulsion pot, is stirred evenly, then will vacuumized in emulsion pot, emulsifying 10 divides
Clock；
5,15 minutes are kept the temperature, then opens cooling and be water-cooled to 40 DEG C, aminomethyl propanol and plant society described in embodiment 1 is added
Object ferments magma (I), stirs evenly；
6,35 DEG C are cooled to, qualified discharging is examined.
2 balance skin Tiny ecosystem mask of Application Example
A kind of balance skin Tiny ecosystem mask containing plant composition of the present invention fermentation magma, formula are shown in Table 6.
Table 6
| Component | Mass fraction/% |
| Deionized water | To 100 |
| Glycerol | 10.00 |
| 1,3- propylene glycol | 7.00 |
| Sodium Hyaluronate | 0.10 |
| Xanthan gum | 0.10 |
| Hydroxyethyl cellulose | 0.10 |
| Allantoin | 0.50 |
| Panthenol | 1.00 |
| 1,2- hexylene glycol | 0.60 |
| Parahydroxyacet-ophenone | 0.50 |
| Plant composition described in embodiment 1 ferments magma (I) | 30.00 |
The preparation method is as follows:
(1) xanthan gum and Sodium Hyaluronate are dispersed in advance in glycerol, then with allantoin, panthenol, hydroxyethyl cellulose one
It rises and puts into deionized water, be heated to 80 DEG C, stirring and dissolving to homogeneous transparent cools down；
(2) parahydroxyacet-ophenone is dissolved by heating in advance to transparent in 1,3-PD and 1,2- hexylene glycol, is cooled down in system
Investment stirring and dissolving is to transparent when to 55 DEG C；
(3) when being cooled to 40 DEG C, plant composition described in embodiment 1 fermentation magma (I) investment is evenly stirred until completely molten
Solution；
(4) color, pH, fragrance, the physical and chemical indexes such as appearance, after the assay was approved 200 mesh filtering and discharging are examined.
3 balance skin Tiny ecosystem Essence of Application Example
A kind of balance skin Tiny ecosystem Essence containing plant composition of the present invention fermentation magma, the specific formula of the Essence
As shown in table 7.
Table 7
Above-mentioned Essence, preparation method are as follows:
1, addition phase raw material parahydroxyacet-ophenone is dissolved by heating in 1,2- hexylene glycol to clear in advance, it is spare；
2, water phase is put into deionized water, is stirred evenly, heating stirring is to 75 ~ 85 DEG C；
3,10 minutes are kept the temperature, then opens cooling water temperature to 60 DEG C, be slowly added to while stirring in advance in 1,2- hexylene glycol
The parahydroxyacet-ophenone dissolved, stirring is to being uniformly dissolved；
4,40 DEG C are cooled to, plant composition fermentation magma of the present invention is added；
5, it stirs evenly, is cooled to 35 DEG C, 300 mesh discharge after surveying pH qualification.
4 balance skin Tiny ecosystem toner of Application Example
A kind of balance skin Tiny ecosystem toner containing plant composition of the present invention fermentation magma, the specific formula of the toner
As shown in table 8.
Table 8
| Ingredient | Mass fraction/% |
| EDTA-2Na | 0.02 |
| Glycerol | 5 |
| Panthenol | 0.2 |
| 1,3 butylene glycol | 5 |
| Sodium Hyaluronate | 0.08 |
| Parahydroxyacet-ophenone | 0.4 |
| Phenoxyethanol | 0.3 |
| Essence | 0.1 |
| Plant composition fermentation magma of the present invention | Surplus |
The preparation method is as follows:
(1) EDTA-2Na, glycerol, panthenol are mixed and are heated to 80 DEG C, stirring is complete to transparent dissolution；
(2) it after being mixed and stirred for raw material 1,3-BDO, Sodium Hyaluronate uniformly at normal temperature, is added to obtained by step (1)
Solution in, 80 DEG C keep the temperature 10 minutes, be stirred until homogeneous；
(3) stirring is cooled to 45 DEG C, and surplus stock is added, stirs evenly；
(4) vacuum defoamation, 38 DEG C with bottom discharge, Material is aqueous solution.
The lotion of 1 extracting solution containing plant composition of Comparison study example
Compared with Application Example 1, in addition to by plant composition fermentation magma (I) be changed to comparative example 6 other than, other conditions with answer
It is identical with embodiment 1.
The mask of 2 extracting solution containing plant composition of Comparison study example
Compared with Application Example 2, in addition to by plant composition fermentation magma (I) be changed to comparative example 6 other than, other conditions with answer
It is identical with embodiment 1.
The common mask of Comparison study example 3
Compared with Application Example 2, in addition to by plant composition fermentation magma (I) be changed to deionized water other than, other conditions with
Application Example 1 is identical.
Application effect example 1 inhibits acne and moisture-keeping efficacy test evaluation
1, the preparation of sample
It is that sample carries out following inhibition acne efficacy test with Application Example 1 and Comparison study example 1.
2, experimental method
Choosing bilateral face has obvious acne, is in newborn or inflammatory phase, and facial area skin belongs to easy long acne type will
Hope person 30, the age, men and women was fifty-fifty at 20~35 years old, carried out half face test.Volunteer need as required once in the morning and once at night into
The product of half face of row is smeared, continuous 28 days on probation.
Inhibit acne evaluation content: the acne of 2 Whiteheads of volunteer's left and right face, blackhead ranks being carried out a
Several labels and number statistical.According to the inhibitory effect to acne, collects half face and test evaluation table on probation.
Moistening effect evaluation content: the left and right nasolabial groove part for choosing volunteer carries out skin moisture content and water loss
(TEWL) it tests, takes the average value of 3 values as left and right nasolabial groove moisture content data (d0) and nasolabial groove skin water loss
(TEWL) data (d0).After test, volunteer need to use as required, and a side face smears embodiment product, another side face
Comparative example product is smeared, re-test moisture content data (d28) after 28 days and nasolabial groove skin water loss (TEWL) are used
Data (d28).
3, experimental result
Inhibit acne evaluation result as shown in table 9.
Table 9
The results show that the effect of Application Example 5 and Comparison study example 1, there are notable difference, illustrates wherein containing plant of the present invention
The product of composition fermentation magma has good inhibitory effect to acne, and plant composition inhibits acne after fermentation process
Ability is obviously improved.
Moistening effect evaluation result is as shown in table 10.
10 moisture content of table tests change rate (%)
As seen from the results in Table 10, the lotion of the lotion and Comparison study example 1 that prepared by Application Example 1 of the present invention all has good guarantor
Wet effect, but Application Example 1 has better moistening effect than Comparison study example 1, illustrates that plant composition of the present invention passes through
Play the role of moisturizing synergy after fermentation process.
The 2 normal individual trial evaluation test of application effect example
1, test population: 60 people of personnel for selecting face skin drying, red swelling of the skin, convulsion to itch, the age, men and women was each at 18-28 years old
Half, 2 groups are randomly divided into, every group of 15 males, 15 women.It is required that subject's health, can by Normalization rule cosmetics,
To cosmetics hyperesthesia, can accurately be judged after use.
2, test sample: mask prepared by Application Example 2, Comparison study example 2-3.
3, test method: before subject tries out sample, first voluntarily face cleaning, after drying, fixed point is used primary daily.First group
The mask that the left face of user is prepared using Application Example 2, the mask that right face uses Comparison study example 2 to prepare；Second group
The mask that the left face of user is prepared using Application Example 2, the mask that right face uses Comparison study example 3 to prepare.Persistently make
Skin condition with one month, behind observation use front and back.Subject during test cannot use other any cosmetics or its
His drug, avoids staying up late, smokes and keep bland diet.To sample moisturizing degree, degree of highlighting, mildness, exquisiteness in use process
Degree, elasticity are evaluated, and wherein highest is divided into 5 points, minimum to be divided into 1 point.
4, test result
The practical effect of sample is tracked and recorded, the feedback opinion and finishing analysis of collecting test person, statistical result
It is shown in Table 11.
11 normal individual trial result average value of table
| Evaluation result | Application Example 2 | Comparison study example 2 | Comparison study example 3 |
| Moisturizing degree | 4.4 | 3.5 | 2.7 |
| Degree of highlighting | 3.6 | 3.1 | 2.2 |
| Mildness | 4.7 | 4.3 | 4.7 |
| Sophistication | 4.1 | 3.4 | 2.9 |
| Elastic effect | 4.1 | 3.2 | 2.3 |
By 11 result of table as it can be seen that Application Example of the present invention 2 has good using effect, and Application Example of the present invention 2
It is better than Comparison study example 3 with the using effect of the mask of the preparation of Comparison study example 2, illustrate magma of fermenting using plant composition
The effect of improving skin is all had with plant composition extract；On the other hand, mask prepared by Application Example 2 of the present invention
Than Comparison study example 2 prepare mask using effect more preferably, illustrate that plant composition effect after fermentation process is more preferable.
Specific embodiments of the present invention are described in detail above, but it is merely an example, the present invention is simultaneously unlimited
It is formed on particular embodiments described above.To those skilled in the art, any couple of present invention carries out equivalent modifications and
Substitution is also all among scope of the invention.Therefore, without departing from the spirit and scope of the invention made by equal transformation and
Modification, all should be contained within the scope of the invention.
Claims (7)
- The magma 1. a kind of plant composition of balance skin Tiny ecosystem ferments, which is characterized in that the plant composition proferment Slurry is made of the component of following parts by weight: 5-50 parts of semen coicis, 5-40 parts of radix polygonati officinalis, 5-30 parts of centella, 5-30 parts of schizonepeta, celestial being People slaps 5-30 parts.
- The magma 2. a kind of plant composition of balance skin Tiny ecosystem ferments, which is characterized in that the plant composition proferment Slurry is made of the component of following parts by weight: 20-40 parts of semen coicis, 20-25 parts of radix polygonati officinalis, 15-20 parts of centella, schizonepeta 10-20 Part, 10-20 parts of cactus.
- 3. the described in any item plant composition fermentation magma of claim 1-2 use following preparation method: being mentioned using fermentation It follows the example of, i.e., after plant composition being carried out fermentation process, using filter, sterilizing and centrifugal separation, decolourizes, balance skin is obtained by filtration The plant composition fermentation magma of skin Tiny ecosystem；Specifically comprise the following steps: that bacterium used in the 1. described fermentation is Lactococcus lactis Bacterium, fermentation bacteria used thereby are added in the form of bacterium solution, bacterial concentration 105-108cfu/mL；2. stock: each plant material is removed Miscellaneous, cleaning, is crushed to 20-200 mesh, mixes, obtains plant composition；Compound concentration is 105-108 The bacterium solution of cfu/mL, pH value It is adjusted to 6.5-7.5；3. fermentation: according to the ratio mixing bacterium solution, plant composition and water, in 28-45 DEG C, 50-300r/min item It ferments 40-72 hours in part, obtains fermentation liquid；4. purification: by gained filtering fermentation liquor, at a temperature of height of the filtrate at 105-125 DEG C Pressure sterilizing 20-40min；By the ferment filtrate after sterilizing 3000-8000r/min, centrifugation radius be 5-20cm under conditions of from Heart 10-35min abandons precipitating, collects supernatant, with active carbon decoloring, filtrate is collected in filtering, as balance skin Tiny ecosystem Plant composition fermentation magma.
- 4. the plant composition fermentation magma of the described in any item balance skin Tiny ecosystems of claim 1~2 is preparing cosmetics In application.
- 5. application according to claim 4, it is characterised in that: the plant composition of the balance skin Tiny ecosystem ferments Additive amount of the magma in cosmetics is 0.1~100% based on mass fraction.
- 6. a kind of cosmetics, it is characterised in that: the plant containing the described in any item balance skin Tiny ecosystems of claim 1~2 Composition fermentation magma.
- 7. cosmetics according to claim 6, it is characterised in that: the cosmetics contain based on mass fraction for 0.1~ The plant composition fermentation magma of 100% balance skin Tiny ecosystem；The cosmetics are as follows: aqua, type of latex type, cream kind, face Pad pasting class, powder class, spray-like, essence class, washes shield class at gel class.
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| CN112716850A (en) * | 2021-01-15 | 2021-04-30 | 曾万祥 | Composition capable of regulating skin microecological balance and application thereof |
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