CN110882207A - Preparation process and method of essence for skin repair - Google Patents

Preparation process and method of essence for skin repair Download PDF

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CN110882207A
CN110882207A CN201911344126.XA CN201911344126A CN110882207A CN 110882207 A CN110882207 A CN 110882207A CN 201911344126 A CN201911344126 A CN 201911344126A CN 110882207 A CN110882207 A CN 110882207A
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skin
oligopeptide
essence
leaf
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CN110882207B (en
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于进勇
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Guangzhou Man Shan Biotechnology Co ltd
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Beijing Mimu Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14Liposomes; Vesicles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
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  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to the field of animal and plant application research (combination), in particular to a preparation process and a method of essence for skin repair, which comprises the following raw materials of propolis extract, honey extract, royal jelly extract, β -glucan, acetyl hexatitanium-8, myotitanium, oligopeptide-32, oligopeptide-1, peony flower/leaf/root extract, aloe vera extract, carbomer, xanthan gum, mung bean extract, centella asiatica extract, plantain extract, hypericum perforatum extract, rosemary leaf water, imidazolidinyl urea, xylitol, caprylyl hydroximic acid, glycerol, sodium hyaluronate, butanediol and water.

Description

Preparation process and method of essence for skin repair
Technical Field
The invention relates to the field of animal and plant application research (combination), in particular to a preparation process and a method of essence for skin repair.
Background
In real life, a plurality of factors can cause damage to skin cells and tissues of a human body, and the human body has a certain regeneration and self-repair capacity, namely healthy cells which survive after injury are continuously divided and proliferated to replace dead cells and repair damaged tissues. Regeneration and self-repair are one of the self-defense mechanisms obtained by the biological world in the long-term evolution process, and the purpose is to protect self and prolong the existing time of self, but for more serious damage, self-repair cannot be restored to the original state anyway, so that external medicines or cosmetics are needed to assist repair.
In the prior art, skin repair cosmetics are widely applied, which mainly supplement nutrition from cell roots, improve cell activity, further promote skin metabolism, promote skin microvascular circulation, maintain the integrity of red blood cells, white blood cells and epithelial cells, prevent drying and cracking, further recover and maintain the natural elasticity of skin, and promote the regeneration of epidermal cells.
During a particular use, some users are not satisfied with the existing skin repair results and further research is needed.
Disclosure of Invention
In order to solve the problems, the invention aims to provide a preparation process and a preparation method of essence for skin repair, wherein animal extracts such as propolis extract, honey extract and royal jelly extract are matched with plant extracts such as peony flower/leaf/root extract, aloe vera extract, mung bean extract, centella asiatica extract and plantain extract to prepare the essence which has the effects of repairing skin injury, supplementing skin nutrition, improving skin blood circulation, renewing skin cell regeneration, improving skin elasticity and softness, improving skin quality, removing skin melanin and whitening and brightening skin.
In order to achieve the above object, the present invention adopts the following aspects
An essence for skin repair is composed of the following raw materials:
propolis extract, honey extract, royal jelly extract, β -glucan, acetyl hexatitanium-8, myotitanium, oligopeptide-32, oligopeptide-1, peony/leaf/root extract, aloe vera extract, carbomer, xanthan gum, mung bean extract, centella asiatica extract, plantain extract, hypericum perforatum extract, rosemary leaf water, imidazolidinyl urea, xylitol, caprylyl hydroxamic acid, glycerol, sodium hyaluronate, butylene glycol, water.
Preferably, the essence for skin repair comprises, by mass, 0.2-1.0% of propolis extract, 0.2-0.8% of honey extract, 0.1-0.5% of royal jelly extract, 0.2-0.5% of β -glucan, 0.1-0.3% of acetyl hexatitanium, 0.2-0.5% of myotitanium, 0.1-0.3% of oligopeptide-320, 10.1-0.3% of oligopeptide-10.1, 1.0-5.0% of peony flower/leaf/root extract, 1.0-5.0% of aloe vera extract, 0.1-0.5% of carbomer, 0.1-0.5% of xanthan gum, 1.0-5.0% of mung bean extract, 1.0-5.0% of centella asiatica extract, 1.0-5.0% of plantain extract, 1.0-5.0% of hypericum perforatum extract, 1.0-3.0% of rosemary leaf water, 0.1-0.1.1.0% of imidazolidinyl urea, 0.1-0.1.0% of xylitol, 0.5-0.0% of caprylyl sodium hyaluronate, and the balance of sodium caprylate.
Preferably, the essence for skin repair comprises, by mass, 0.6% of propolis extract, 0.5% of honey extract, 0.3% of royal jelly extract, β -glucan 0.3%, acetyl hexatitanium-80.2%, myotitanium 0.4%, oligopeptide-320.2%, oligopeptide-10.2%, 3.0% of peony flower/leaf/root extract, 3.0% of aloe vera extract, 0.3% of carbomer, 0.3% of xanthan gum, 3.0% of mung bean extract, 3.0% of centella asiatica extract, 3.0% of plantain herb extract, 3.0% of hypericum perforatum extract, 2.0% of rosemary leaf water, 0.3% of imidazolidinyl urea, 2.0% of xylitol, 0.08% of caprylyl hydroximic acid, 1.0% of glycerin, 0.4% of sodium hyaluronate, 2.5% of butylene glycol, and the balance of water.
A preparation process and a method of essence for skin repair comprise the following steps:
s1 performing mixed fermentation of lactobacillus on the peony/leaf/root extract, the aloe barbadensis extract, the mung bean extract, the centella asiatica extract and the plantain extract to obtain a mixture A;
s2, adding butanediol into the mixture A, and uniformly stirring to obtain a mixture B;
s3 mixing propolis extract, Mel extract, Lac Regis Apis extract, β -dextran, acetyl hexatitanium-8, Mytilis, oligopeptide-32, oligopeptide-1, carbomer, xanthan gum, herba Hyperici perforati extract, herba Rosmarini officinalis leaf water, xylitol, glycerol, sodium hyaluronate and water, and stirring;
s4, adding the mixture B, the caprylyl hydroximic acid and the imidazolidinyl urea, and uniformly stirring;
s5 cooling to room temperature to obtain the essence for skin repair.
Preferably, in step S1, the fermentation conditions: the temperature is 10-15 deg.C, and the time is 90-150 min.
Preferably, in step S2, the butanediol is added at a constant rate during the stirring process.
Preferably, in step S3, stirring is carried out at 60-70 ℃ for 30-40min at a speed of 200-300 rpm.
Preferably, in step S4, the temperature is reduced to 45-50 ℃, the mixture B, the octanoyl hydroxamic acid and the imidazolidinyl urea are added, and the mixture is stirred for 20-30min at the speed of 200-300 rpm.
In the invention
Propolis extract: the natural protective agent is rich in various nutrient substances, has a famous healing effect, and can promote wound healing, relieve pain, resist inflammation, resist oxidation and the like.
And (3) honey extract: the humectant effectively regulates the water balance in the skin, softens the horny layer and enables the horny layer to recover elasticity and softness; the honey has effects of astringing, nourishing and promoting wound healing.
Royal jelly extract: it is rich in protein, amino acids, vitamins, especially vitamin B in Lac Regis Apis, and has nourishing and skin caring effects. The large amount of active substance contained in the extract activates the enzyme system, excretes lipofuscin and reduces its content; it also has antibacterial, antiinflammatory, and radioprotective effects, and can be used for preventing skin infection, inflammation and radiation injury, preventing skin melanin formation, preventing and eliminating wrinkle, caring skin, keeping skin clean and white, and keeping skin tender, beautiful and healthy.
Peony/leaf/root extract; has the antifungal effects: bacteria of tinea, candida, acne and the like; and (3) antivirus: foot and mouth disease virus, avian influenza, etc.; and (3) antiallergic: inhibiting various anaphylactic reactions; antioxidant efficacy: is superior to green tea extract at the same concentration.
Aloe vera extract; it has effects of relieving sclerosis and keratinization, improving scar, preventing small wrinkle, eye pouch, and cutis laxa, keeping skin moist and delicate, treating skin inflammation, and treating acne, freckle, and acne.
Mung bean extract; the mung bean has the antibacterial and bacteriostatic effects, certain components in the mung bean have the antibacterial effect directly, and the antibacterial effect is indirectly exerted by improving the immune function; the oyster alkali and the iso-oyster alkali in the mung bean extract have excellent cleaning and moisturizing effects, the sebum removing function is obvious, unclean substances in the skin can be effectively removed, deep waste of the skin can be thoroughly removed, and the skin is bright, clean and transparent; the mung bean moisture-keeping agent improves the moisture-keeping components and mineral substances of dry skin, supplies sufficient moisture to the skin, effectively strengthens the moisture-keeping capacity of the skin, and the natural polysaccharide forms a transparent and elastic moisture-keeping film on the surface layer of the skin to make the skin moist and elastic.
Centella asiatica extract; has effects in supplementing skin collagen, removing acne and acne marks, relieving inflammation, repairing, and resisting oxidation.
Plantain herb extract: the plantain polysaccharide has antibacterial, bactericidal and antioxidant effects, and can relieve free radical damage in cells by improving activity of antioxidant enzyme in vivo.
The invention has the beneficial effects that: the invention is prepared by combining animal extracts such as propolis extract, honey extract, royal jelly extract and the like with plant extracts such as peony flower/leaf/root extract, aloe barbadensis extract, mung bean extract, centella extract, plantain extract and the like, and has the effects of repairing skin injury, supplementing skin nutrition, improving skin blood circulation, renewing skin cell regeneration, enhancing skin elasticity and softness, improving skin quality, removing skin yellow melanin and whitening and brightening skin; the plant extracts are mixed and fermented firstly, so that the absorption efficiency of the plant extracts is improved, and the butanediol is added into the fermented product to form a grease film inclusion body, so that the content is prevented from being further fermented, and meanwhile, the content is prevented from being invaded by bacteria in the subsequent process.
Detailed Description
In order to make those skilled in the art better understand the technical solutions in the present application, the following will clearly and completely describe the technical solutions in the present application with reference to the embodiments, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and all other embodiments obtained by a person of ordinary skill in the art without making creative efforts based on the embodiments in the present application shall fall within the protection scope of the present application.
Example 1
An essence for skin repair comprises, by mass, 0.6% of a propolis extract, 0.5% of a honey extract, 0.3% of a royal jelly extract, β -glucan 0.3%, acetyl hexatitanium-80.2%, myotitanium 0.4%, oligopeptide-320.2%, oligopeptide-10.2%, 3.0% of a peony flower/leaf/root extract, 3.0% of an aloe vera extract, 0.3% of carbomer, 0.3% of xanthan gum, 3.0% of a mung bean extract, 3.0% of an centella asiatica extract, 3.0% of a plantain herb extract, 3.0% of a hypericum perforatum extract, 2.0% of rosemary leaf water, 0.3% of imidazolidinyl urea, 2.0% of xylitol, 0.08% of caprylyl hydroxamic acid, 1.0% of glycerin, 0.4% of sodium hyaluronate, 2.5% of butylene glycol, and the balance water.
Example 2
An essence for skin repair comprises, by mass, 0.2% of a propolis extract, 0.8% of a honey extract, 0.1% of a royal jelly extract, β -glucan 0.5%, acetyl hexatitanium-80.3%, myotitanium 0.2%, oligopeptide-320.3%, oligopeptide-10.1%, 5.0% of a peony flower/leaf/root extract, 1.0% of an aloe vera extract, 0.5% of carbomer, 0.1% of xanthan gum, 5.0% of a mung bean extract, 1.0% of an centella asiatica extract, 5.0% of a plantain herb extract, 1.0% of a hypericum perforatum extract, 3.0% of rosemary leaf water, 0.1% of imidazolidinyl urea, 3.0% of xylitol, 0.05% of caprylyl hydroxamic acid, 1.5% of glycerin, 0.2% of sodium hyaluronate, 4.0% of butylene glycol, and the balance water.
Example 3
An essence for skin repair comprises, by mass, 1.0% of a propolis extract, 0.2% of a honey extract, 0.5% of a royal jelly extract, β -glucan 0.2%, 80.3% of acetyl hexatitanium, 0.2% of myotitanium, 320.1% of oligopeptide, 10.3% of oligopeptide, 1.0% of a peony flower/leaf/root extract, 5.0% of an aloe vera extract, 0.1% of carbomer, 0.5% of xanthan gum, 1.0% of a mung bean extract, 5.0% of a centella asiatica extract, 1.0% of a plantain herb extract, 1.0% of a hypericum perforatum extract, 1.0% of rosemary leaf water, 0.4% of imidazolidinyl urea, 1.0% of xylitol, 0.1% of caprylyl hydroxamic acid, 0.5% of glycerin, 0.6% of sodium hyaluronate, 1.0% of butylene glycol, and the balance of water.
The preparation process and method of essence for skin repair as described in any one of embodiments 1 to 3, comprising the steps of:
s1 performing mixed fermentation of lactobacillus on the peony/leaf/root extract, the aloe barbadensis extract, the mung bean extract, the centella asiatica extract and the plantain extract to obtain a mixture A, wherein the fermentation conditions are as follows: the temperature is 12 ℃, and the time is 120 min;
s2, adding butanediol into the mixture A, uniformly stirring to obtain a mixture B, and adding the butanediol at a constant speed in the stirring process;
s3 mixing propolis extract, Mel extract, Lac Regis Apis extract, β -dextran, acetyl hexatitanium-8, Mytilis, oligopeptide-32, oligopeptide-1, carbomer, xanthan gum, herba Hyperici perforati extract, herba Rosmarini officinalis leaf water, xylitol, glycerol, sodium hyaluronate and water, stirring at 65 deg.C for 35min at 250 rpm;
s4 cooling to 50 ℃, adding the mixture B, the octanoyl hydroximic acid and the imidazolidinyl urea, and stirring for 25min at the speed of 260 rpm;
s5 cooling to room temperature to obtain the essence for skin repair.
Experimental example 1 post-sunburn restoration Effect experiment
In comparative example 1, the plant extracts were not mixed and fermented first, and the other preparation processes were the same.
Comparative example 2, plant extracts were mixed and fermented without treatment with butylene glycol, and the other preparation procedures were the same.
The same amount of the essence for skin repair prepared in examples 1 to 3 was taken and compared with the comparative examples 1 and 2, respectively, for clinical experiment under the following conditions: 100 volunteers aged 20-40 years are randomly divided into 5 groups, 20 volunteers in each group are all people with skin sunburn sequelae, affected parts have symptoms of redness, itching, burning, stabbing pain or red blood streak, other skin care products are not smeared on the tested parts in the testing period, the skin care products are respectively smeared in the morning and at the evening every day for four weeks, the number of people with improved skin conditions is counted once a week, and the experimental results are shown in a table I.
Figure BDA0002332144470000061
Figure BDA0002332144470000071
Watch 1
The data show that the traditional Chinese medicine composition has a good repairing effect and takes effect more quickly in the process of repairing the skin after sunburn, and is suitable for more people.
Experimental example 2 anti-aging Effect experiment
Comparative example 1, a conventional repair cream of the same price was purchased.
In comparative example 2, the plant extracts were not mixed and fermented first, and the other preparation processes were the same.
Comparative example 3, plant extracts were mixed and fermented without treatment with butylene glycol, and the other preparation procedures were the same.
The same amount of the essence for skin repair prepared in examples 1 to 3 and the same amount of the essence for skin repair prepared in comparative examples 1 to 3 were taken, respectively, and clinical experimental comparisons were performed under the following clinical experimental conditions: 600 volunteers aged 45-60 years were randomly divided into 6 groups of 100 persons each, tried for 45 days continuously, applied to the face and neck skin every day, and any other skin care product was not applied to the test site during the test period, and comparative analysis was conducted to evaluate the anti-aging effect of the cosmetics prepared in each of the above examples and comparative examples. Wherein, the anti-aging effect is the improvement condition of fine and smooth face and neck complexion, white skin, wrinkle reduction, skin elasticity and the like, and the experimental result is shown in the table two.
Figure BDA0002332144470000072
Figure BDA0002332144470000081
Watch two
The data show that the anti-aging health-care tea has good overall effect on the comparison of anti-aging effects of people after age 45, and is suitable for more people.
Finally, the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting, and other modifications or equivalent substitutions made by the technical solutions of the present invention by those of ordinary skill in the art should be covered within the scope of the claims of the present invention as long as they do not depart from the spirit and scope of the technical solutions of the present invention.

Claims (8)

1. The essence for repairing the skin is characterized by comprising the following raw materials:
propolis extract, honey extract, royal jelly extract, β -glucan, acetyl hexatitanium-8, myotitanium, oligopeptide-32, oligopeptide-1, peony/leaf/root extract, aloe vera extract, carbomer, xanthan gum, mung bean extract, centella asiatica extract, plantain seed extract, hypericum perforatum extract, rosemary leaf water, imidazolidinyl urea, xylitol, caprylhydroxamic acid, glycerol, sodium hyaluronate, butylene glycol, water.
2. The essence for skin rejuvenation according to claim 1, wherein the constituents by mass percentage are propolis extract 0.2-1.0%, honey extract 0.2-0.8%, royal jelly extract 0.1-0.5%, β -dextran 0.2-0.5%, acetyl hexatitanium-80.1-0.3%, myotitanium 0.2-0.5%, oligopeptide-320.1-0.3%, oligopeptide-10.1-0.3%, peony flower/leaf/root extract 1.0-5.0%, aloe vera extract 1.0-5.0%, carbomer 0.1-0.5%, xanthan gum 0.1-0.5%, mung bean extract 1.0-5.0%, centella asiatica extract 1.0-5.0%, plantago extract 1.0-5.0%, hyperforin perforatum extract 1.0-5.0%, rosemary leaf water 1.0-3.0%, imidazolidinyl urea 0.1-5.0%, xylitol 4.1.0-0%, and sodium caprylate 0.5%, and the balance of glycerin.
3. The essence for skin rejuvenation according to claim 2 comprising, by mass, 0.6% of propolis extract, 0.5% of honey extract, 0.3% of royal jelly extract, 0.3% of β -dextran, 80.2% of acetylhexatitanium, 0.4% of myotitanium, 320.2% of oligopeptide, 10.2% of oligopeptide, 3.0% of peony flower/leaf/root extract, 3.0% of aloe vera extract, 0.3% of carbomer, 0.3% of xanthan gum, 3.0% of mung bean extract, 3.0% of centella asiatica extract, 3.0% of plantain extract, 3.0% of hypericum perforatum extract, 2.0% of rosemary leaf water, 0.3% of imidazolidinyl urea, 2.0% of xylitol, 0.08% of caprylyl hydroximic acid, 1.0% of glycerin, 0.4% of sodium hyaluronate, 2.5% of butylene glycol, and the balance of water.
4. The preparation process and method of essence for skin repair according to claim 1, comprising the steps of:
s1 performing mixed fermentation of lactobacillus on the peony/leaf/root extract, the aloe barbadensis extract, the mung bean extract, the centella asiatica extract and the plantain extract to obtain a mixture A;
s2, adding butanediol into the mixture A, and uniformly stirring to obtain a mixture B;
s3 mixing propolis extract, Mel extract, Lac Regis Apis extract, β -dextran, acetyl hexatitanium-8, Mytilis, oligopeptide-32, oligopeptide-1, carbomer, xanthan gum, herba Hyperici perforati extract, herba Rosmarini officinalis leaf water, xylitol, glycerol, sodium hyaluronate and water, and stirring;
s4, adding the mixture B, the caprylyl hydroximic acid and the imidazolidinyl urea, and uniformly stirring;
s5 cooling to room temperature to obtain the essence for skin repair.
5. The process and method for preparing essence for skin repair according to claim 4, wherein in step S1, the fermentation conditions are: the temperature is 10-15 deg.C, and the time is 90-150 min.
6. The process for preparing essence for skin repair and the method thereof according to claim 4, wherein in step S2, butanediol is added at a constant speed during the stirring process.
7. The process and method for preparing essence for skin repair according to claim 4, wherein in step S3, stirring is performed at 60-70 ℃ for 30-40min at 200-300 rpm.
8. The process for preparing essence for skin repair according to claim 4, wherein in step S4, the temperature is reduced to 45-50 ℃, the mixture B, the caprylyl hydroxamic acid and the imidazolidinyl urea are added, and the mixture is stirred for 20-30min at the speed of 200-300 rpm.
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CN111358704A (en) * 2020-05-18 2020-07-03 中研(上海)化妆品销售有限公司 Deep-repairing anti-aging composition and preparation method and application thereof
CN111991319A (en) * 2020-10-11 2020-11-27 广州莱约生物科技有限公司 Repair composition, preparation method and application thereof
CN113456517A (en) * 2021-07-02 2021-10-01 上海美莲妮生物科技有限公司 Moisture-preserving and repairing pure liquid and preparation method thereof
CN113925805A (en) * 2021-09-14 2022-01-14 上海植纳生物科技有限公司 Peony cell fermentation liquor and preparation method and application thereof
CN114099364A (en) * 2021-12-09 2022-03-01 北京中蜜科技发展有限公司 Emulsion containing royal jelly enzymolysis polypeptide and preparation method thereof
CN115154398A (en) * 2022-08-26 2022-10-11 妙托日用品科技(广州)有限公司 Moisturizing and skin-care composition for pregnant women and application of moisturizing and skin-care composition in mask
CN115969739A (en) * 2023-01-05 2023-04-18 广州科堡化妆品有限公司 Shampoo beneficial to improving hair luster

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CN111358704A (en) * 2020-05-18 2020-07-03 中研(上海)化妆品销售有限公司 Deep-repairing anti-aging composition and preparation method and application thereof
CN111991319A (en) * 2020-10-11 2020-11-27 广州莱约生物科技有限公司 Repair composition, preparation method and application thereof
CN113456517A (en) * 2021-07-02 2021-10-01 上海美莲妮生物科技有限公司 Moisture-preserving and repairing pure liquid and preparation method thereof
CN113925805A (en) * 2021-09-14 2022-01-14 上海植纳生物科技有限公司 Peony cell fermentation liquor and preparation method and application thereof
CN113925805B (en) * 2021-09-14 2023-05-23 上海植纳生物科技有限公司 Peony cell fermentation broth and preparation method and application thereof
CN114099364A (en) * 2021-12-09 2022-03-01 北京中蜜科技发展有限公司 Emulsion containing royal jelly enzymolysis polypeptide and preparation method thereof
CN114099364B (en) * 2021-12-09 2023-11-10 北京中蜜科技发展有限公司 Emulsion containing royal jelly enzymolysis polypeptide and preparation method thereof
CN115154398A (en) * 2022-08-26 2022-10-11 妙托日用品科技(广州)有限公司 Moisturizing and skin-care composition for pregnant women and application of moisturizing and skin-care composition in mask
CN115969739A (en) * 2023-01-05 2023-04-18 广州科堡化妆品有限公司 Shampoo beneficial to improving hair luster
CN115969739B (en) * 2023-01-05 2023-08-29 广州科堡化妆品有限公司 Shampoo beneficial to improving hair luster

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